34 ANNUAL MEETING of the HISTIOCYTE SOCIETY

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34 ANNUAL MEETING of the HISTIOCYTE SOCIETY 34TH ANNUAL MEETING of the HISTIOCYTE SOCIETY MEETING PROGRAM AND ABSTRACTS EPIC SANA LISBOA LISBON, PORTUGAL OCTOBER 22 - 23, 2018 WWW.HISTIOCYTESOCIETY.ORG 2 HISTIOCYTE SOCIETY ANNUAL MEETING 2018 TABLE OF CONTENTS WELCOME TO LISBON ......................................................................................................................................................................... 5 ABOUT THE HISTIOCYTE SOCIETY .................................................................................................................................................... 6 2018 ANNUAL MEETING MOBILE APP ............................................................................................................................................... 6 ANNUAL MEETING PROGRAM ............................................................................................................................................................ 6 HISTIOCYTOSIS ASSOCIATION AND HISTIOCYTE SOCIETY .......................................................................................................... 7 ACKNOWLEDGEMENTS AND RECOGNITIONS ................................................................................................................................. 8 EPIC SANA LISBOA HOTEL FLOOR PLAN ...................................................................................................................................... 10 AT-A-GLANCE MEETING AGENDA ................................................................................................................................................... 11 IN MEMORIAM: DR. GUILIO D’ANGIO ............................................................................................................................................... 13 GUEST SPEAKER HIGHLIGHTS ........................................................................................................................................................ 14 MEET THE EXPERTS PRESENTER HIGHLIGHTS ........................................................................................................................... 16 EDUCATION SESSIONS PRESENTER HIGHLIGHTS ....................................................................................................................... 17 MEETING AGENDA ............................................................................................................................................................................. 19 POSTER LOCATION MAP ................................................................................................................................................................... 31 GUEST SPEAKER PRESENTATIONS ................................................................................................................................................ 34 SCIENTIFIC SESSION I ABSTRACTS ................................................................................................................................................ 36 SCIENTIFIC SESSION II: PRESIDENTIAL SYMPOSIUM ABSTRACTS ........................................................................................... 39 POSTER PRESENTATION SESSION ABSTRACTS .......................................................................................................................... 42 SCIENTIFIC SESSION III ABSTRACTS .............................................................................................................................................. 77 NESBIT PRIZE IN CLINICAL SCIENCE .............................................................................................................................................. 80 NEZELOF PRIZE IN BASIC SCIENCE ................................................................................................................................................ 80 ROBERT J. ARCECI PRIZE FOR BEST POSTER .............................................................................................................................. 81 HISTIOCYTE SOCIETY GOVERNING BY-LAWS ............................................................................................................................... 82 HISTIOCYTE SOCIETY CONSTITUTION ............................................................................................................................................ 85 PRESENTING AUTHOR INDEX .......................................................................................................................................................... 86 2019 ANNUAL MEETING ANNOUNCEMENT ..................................................................................................................................... 96 MEETING SPONSORS WWW.HISTIOCYTESOCIETY.ORG 3 4 HISTIOCYTE SOCIETY ANNUAL MEETING 2018 WELCOME TO LISBON Dear Colleagues, The Histiocyte Society cordially welcomes you to the 34th Annual Meeting, which is being held in Lisbon, Portugal on October 22-23, 2018. Lisbon, one of the oldest European capitals, is Portugal’s economic and cultural center. It has a worldwide reputation for neoclassical architecture, great food, nostalgic music and romantic places. Its geographic location and pleasant climate make it an attractive location for both business and tourism. Pursuing collaboration with other professional societies is one of the priorities of the Histiocyte Society. Having a back-to- back Meeting with the European Society for Immunodeficiencies Deficiencies (ESID) was another important reason for choosing Lisbon as a venue for our Annual Meeting this year. We would like to strengthen our relationship and promote collaboration in the field of hemophagocytic lymphohistiocytosis. For this reason, we have offered a reduced registration fee to ESID members interested in attending our meeting, will provide a lecture on HLH and primary immune deficiencies followed by a thematic HLH symposium, and will host a working meeting of the leaderships of the two Societies. Our Program Committee put a lot of work into preparing an attractive agenda for this year´s meeting. On the Pre-Meeting day (October 21st) we invite newcomers and young physicians to educational state-of-the-art lectures on diagnosis and treatment of LCH, HLH and rare histiocytoses. This year’s plenary speaker is Prof. Frederic Geissmann, a renowned expert on macrophage biology, who will share new findings on uncovering the pathobiology of CNS-LCH. The traditional Jon Pritchard Lecture on the Nikolas Symposium is dedicated to epigenetics and myeloid differentiation and their implications in histiocytic disorders. The backbone of the meeting program is built by the scientific sessions, the thematic symposia on LCH and HLH, as well as by the Meet the Expert sessions. I hope for a productive scientific exchange and lively discussions in a friendly atmosphere with familial spirit. The social highlight of our meetings is, as always, the Annual Banquet. This year it will take place at Kais Restaurant and Skones Club. After the dinner, the dance floor will be yours till 0100. As you know, a meeting of this format requires a lot of time, energy and resources to be properly organized. I would like to especially appreciate our symbiotic partner and key sponsor, the Histiocytosis Association, without whose generous support, this meeting would not be possible. I look forward to seeing you in Lisbon! Milen Minkov President Histiocyte Society WWW.HISTIOCYTESOCIETY.ORG 5 ABOUT THE HISTIOCYTE SOCIETY The Histiocyte Society is a professional medical association comprised of more than 200 physicians and scientists from around the world. Members of the organization are considered to be the leaders in understanding and treating histiocytic disorders. The Society is committed to advancing knowledge about histiocytic disorders and improving outcomes for patients through the planning, development, sponsorship and oversight of clinical research. Building Knowledge The Histiocyte Society hosts an annual scientific meeting in different locations around the world. Attendance is open to members of the Society as well as other professionals working in the field of histiocytic disorders and related studies. Meetings feature presentations of individual and collective research efforts as well as keynote lectures from guest speakers; special-interest groups convene to discuss and develop new and innovative treatment regimes. This interactive forum allows the best and brightest minds in the histiocytosis community to share the most progressive information and to shape the future of research. Beyond the prolific exchanges that occur during the meeting, presenters work collectively to extend their reach by publishing subsequent articles and manuscripts in scientific journals worldwide. Advancing Treatment Through extensive research and collaboration, the Histiocyte Society has made numerous, significant strides in the fight against histiocytic disorders. The Society has established scientific standards for histiocytic disorders that are accepted worldwide; they include: 1) A common language of uniform disease classification, 2) Standardized diagnostic criteria, and 3) Guidelines for patient evaluation and follow-up. The Society remains dedicated to facilitating essential and innovative clinical research – developing critical knowledge and increasingly effective treatments in the pursuit of a cure. 2018 ANNUAL MEETING MOBILE APP - INVITATION IN YOUR EMAIL The 2018 Histiocyte Society Annual Meeting has a free mobile event app! The best
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