Thymus Hyperplasia After Resolution
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Gonadotrophin-Releasing Hormone Agonist-Induced Pituitary Adenoma Apoplexy and Casual Finding of a Parathyroid Carcinoma: a Case Report and Review of Literature
World Journal of W J C C Clinical Cases Submit a Manuscript: https://www.f6publishing.com World J Clin Cases 2019 October 26; 7(20): 3259-3265 DOI: 10.12998/wjcc.v7.i20.3259 ISSN 2307-8960 (online) CASE REPORT Gonadotrophin-releasing hormone agonist-induced pituitary adenoma apoplexy and casual finding of a parathyroid carcinoma: A case report and review of literature Vanessa Triviño, Olga Fidalgo, Antía Juane, Jorge Pombo, Fernando Cordido ORCID number: Vanessa Triviño Vanessa Triviño, Olga Fidalgo, Antía Juane, Fernando Cordido, Department of Endocrinology, (0000-0001-5649-1310); Olga Fidalgo Complejo Hospitalario Universitario A Coruña, A Coruña 15006, Spain (0000-0002-8559-9416); Antia Juane (0000-0001-8090-2802); Jorge Pombo Jorge Pombo, Department of pathological anatomy, Complejo Hospitalario Universitario A (0000-0002-9624-7053); Fernando Coruña, A Coruña 15006, Spain Cordido (0000-0003-3528-8174). Corresponding author: Fernando Cordido, MD, PhD, Professor, Department of Endocrinology, Author contributions: Triviño V Complejo Hospitalario Universitario A Coruña, University of A Coruña, As xubias 84, A and Fidalgo O were the patient’s Coruña 15006, Spain. [email protected] endocrinologists, reviewed the Telephone: +34-981-176442 literature and contributed to manuscript drafting; Juane A reviewed the literature and contributed to manuscript drafting; Pombo J performed the microscope Abstract study of the tissue and BACKGROUND immunohistochemistry, took the Pituitary apoplexy represents one of the most serious, life threatening endocrine photographs and contributed to emergencies that requires immediate management. Gonadotropin-releasing manuscript drafting; Cordido F was responsible for revision of the hormone agonist (GnRHa) can induce pituitary apoplexy in those patients who manuscript for relevant intellectual have insidious pituitary adenoma coincidentally. -
Fluorescence-Guided Cancer Surgery
a Fluorescence-guided cancer surgery Quirijn Tummers surgeryFluorescence-guided cancer Quirijn Fluorescence-guided cancer surgery using clinical available and innovative tumor-specifc contrast agents Quirijn Tummers 46151 Tummers cover.indd 1 09-08-17 11:17 Fluorescence-guided cancer surgery using clinical available and innovative tumor-specifc contrast agents Quirijn Tummers 46151 Quirijn Tummers.indd 1 16-08-17 13:01 © Q.R.J.G. Tummers 2017 ISBN: 978-94-6332-197-6 Lay-out: Ferdinand van Nispen, Citroenvlinder DTP & Vormgeving, my-thesis.nl Printing: GVO Drukkers & Vormgevers All rights reserved. No parts of this thesis may be reproduced, distributed, stored in a retrieval system or transmitted in any form or by any means, without prior written permission of the author. The research described in this thesis was fnancially supported by the Center for Translational Molecular Imaging (MUSIS project), Dutch Cancer Society and National Institutes of Health. Financial support by Raad van Bestuur HMC Den Haag, Quest Medical Imaging, On Target Laboratories, Centre for Human Drug Research, Curadel, LUMC, Nederlandse Vereniging voor Gastroenterologie, Karl Storz Endoscopie Nederland B.V., ABN-AMRO and Chipsoft for the printing of this thesis is gratefully acknowledged. 46151 Quirijn Tummers.indd 2 16-08-17 13:01 Fluorescence-guided cancer surgery using clinical available and innovative tumor-specifc contrast agents Proefschrift ter verkrijging van de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magnifcus prof. mr. C.J.J.M. Stolker, volgens besluit van het College voor Promoties te verdedigen op woensdag 11 oktober 2017 klokke 15:00 uur door Quirijn Robert Johannes Guillaume Tummers geboren te Leiden in 1986 46151 Quirijn Tummers.indd 3 16-08-17 13:01 Promotor Prof. -
Pseudoischemic Electrocardiogram in Myasthenia Gravis with Thymoma Published Online in Wiley Interscience
Address for correspondence: Nicola Mumoli, MD CaseShort Communication Livorno Hospital Department of Internal Medicine Viale Alfieri 36 Pseudoischemic Electrocardiogram in 57100 Livorno, Italy Myasthenia Gravis with Thymoma: [email protected] Reversibility After Thymectomy Patrizio Chiavistelli, MD, Marco Cei, MD, Giovanni Carmignani, MD, Carlo Bartolomei, MD Nicola Mumoli, MD Department of Internal Medicine, Livorno Hospital, Livorno, Italy Abnormal ST T-wave changes can be found at presentation in various noncoronary disorders; misinterpretation of these patterns as ischemic heart disease can lead to erroneous diagnosis and treatment. Here we present a case of myasthenia gravis (MG) with thymoma, in which the resting electrocardiogram (ECG) led to a misleading diagnosis of myocardial ischemia. After thymectomy, the ECG resumed a normal pattern. Myasthenia gravis is not usually considered in the differential diagnosis of conditions associated with an abnormal ECG. The combination of dysphagia, dyspnoea, ECG changes, and creatine kinase (CK) elevations may easily bring to mind an erroneous and possibly deleterious diagnosis of myocardial ischemia. Introduction did not seek medical attention. At the beginning of the The resting 12-lead electrocardiogram (ECG) remains at current year, he reported a flu-like illness, with spontaneous the center of the diagnostic pathways of acute coronary recovery, but shortly afterward he experienced dyspnea, syndromes (ACSs), either with1 or without ST segment dysphagia, and weight loss (37 kg). One month before elevation,2 because it serves as an invaluable tool for admission, he underwent fiberoptic endoscopy of the nose, both diagnosis and risk stratification. Nevertheless, as is pharynx, and larynx because of dysphonia, without any universally accepted, the predictive value of any diagnostic evidence of an active disease. -
Studies of Thymic Function with Emphasis on the Role of the Thymus in Oncogenesist
[CANCER RESEARCH 26 Part I, 551-574, April 1966] Studies of Thymic Function with Emphasis on the Role of the Thymus in Oncogenesist LLOYDW. LAW National Cancer Institute, Bethesda, Maryland This presentation will be concerned with 2 general topics: organ to other sites occurs with a selective seeding in spleen (a) our present knowledge of thymic structure and function, lymph nodes, and other lymphoid organs. but particularly the latter, as revealed by the results of recent For a more detailed discussion of the ontogeny of the thymus experiments in several species of animals following early thymic and its microscopic anatomy, the reader is referred to the studies ablation, and (b) consideration of the precise role of the thymus in of Smith (97) and of Ruth et al. (92). the initiation and suppression of neoplastic growths. Pertaining to Thymic Structure and Function Origin and Early Structure of the Thymus In most species the thymus is located in the upper anterior The thymus is a compound organ consisting of 3 quite different part of the chest. Exceptions are the chicken and guinea pig. cell systems: (a) lymphoid cells, (b) reticulum cells, and (c) The absolute size varies from species to species but the absolute e[)ithehal cells. The latter 2 may be referred to as the epithelial size of thymic lobules appears to be remarkably uniform in the reticulum cell complex. The thymus in mammals arises as various species, suggesting that there may be a critical limit for paired structures from the endoderm of the 3rd and 4th branchial the size of a thymic lobule. -
Analysis of the Role of Thyroidectomy and Thymectomy in the Surgical Treatment of Secondary Hyperparathyroidism
Am J Otolaryngol 40 (2019) 67–69 Contents lists available at ScienceDirect Am J Otolaryngol journal homepage: www.elsevier.com/locate/amjoto Analysis of the role of thyroidectomy and thymectomy in the surgical ☆ treatment of secondary hyperparathyroidism T Mateus R. Soares, Graziela V. Cavalcanti, Ricardo Iwakura, Leandro J. Lucca, Elen A. Romão, ⁎ Luiz C. Conti de Freitas Division of Head and Neck Surgery, Department of Ophthalmology, Otolaryngology, Head and Neck Surgery, Ribeirao Preto Medical School, University of Sao Paulo, Brazil ARTICLE INFO ABSTRACT Keywords: Purpose: Parathyroidectomy can be subtotal or total with an autograft for the treatment of renal hyperpar- Parathyroidectomy athyroidism. In both cases, it may be extended with bilateral thymectomy and total or partial thyroidectomy. Hyperparathyroidism Thymectomy may be recommended in combination with parathyroidectomy in order to prevent mediastinal Thymectomy recurrence. Also, the occurrence of thyroid disease observed in patients with hyperparathyroidism is poorly Thyroidectomy understood and the incidence of cancer is controversial. The aim of the present study was to report the ex- perience of a single center in the surgical treatment of renal hyperparathyroidism and to analyse the role of thyroid and thymus surgery in association with parathyroidectomy. Materials and methods: We analysed parathyroid surgery data, considering patient demographics, such as age and gender, and surgical procedure data, such as type of hyperparathyroidism, associated thyroid or thymus surgery, surgical duration and mediastinal recurrence. Histopathological results of thyroid and thymus samples were also analysed. Results: Medical records of 109 patients who underwent parathyroidectomy for secondary hyperparathyroidism were reviewed. On average, thymectomy did not have impact on time of parathyroidectomy (p = 0.62) even when thyroidectomy was included (p = 0.91). -
Cellular and Humoral Immune Alterations in Thymectomized Patients for Thymoma
Cellular and humoral immune alterations in thymectomized patients for thymoma Maurizio Lalle, Mauro Minellli, Paola Tarantini, Mirella Marino, Virna Cerasoli, Francesco Facciolo, Cesare Iani, Mauro Antimi To cite this version: Maurizio Lalle, Mauro Minellli, Paola Tarantini, Mirella Marino, Virna Cerasoli, et al.. Cellular and humoral immune alterations in thymectomized patients for thymoma. Annals of Hematology, Springer Verlag, 2009, 88 (9), pp.847-853. 10.1007/s00277-008-0693-3. hal-00535026 HAL Id: hal-00535026 https://hal.archives-ouvertes.fr/hal-00535026 Submitted on 11 Nov 2010 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. Ann Hematol (2009) 88:847–853 DOI 10.1007/s00277-008-0693-3 ORIGINAL ARTICLE Cellular and humoral immune alterations in thymectomized patients for thymoma Maurizio Lalle & Mauro Minellli & Paola Tarantini & Mirella Marino & Virna Cerasoli & Francesco Facciolo & Cesare Iani & Mauro Antimi Received: 1 September 2008 /Accepted: 23 December 2008 /Published online: 23 January 2009 # Springer-Verlag 2009 Abstract The aim of this study was to analyze the impact studies, a longer surveillance and a cooperative approach, of thymectomy on kinetics of the immune reconstitution in due to the rarity of the disease, are necessary to define thymoma patients. -
NCCN Neuroendocrine Tumors Guidelines Are Divided Into 6 Endocrine Systems, Which Produce and Secrete Regulatory Hormones
NCCN Clinical Practice Guidelines in Oncology™ Neuroendocrine Tumors V.1.2007 Continue www.nccn.org Guidelines Index ® Practice Guidelines Neuroendocrine TOC NCCN in Oncology – v.1.2007 Neuroendocrine Tumors MS, References NCCN Neuroendocrine Tumors Panel Members * Orlo H. Clark, MD/Chair ¶ John F. Gibbs, MD ¶ Thomas W. Ratliff, MD † UCSF Comprehensive Cancer Center Roswell Park Cancer Institute St. Jude Children's Research Hospital/University of Tennessee Jaffer Ajani, MD †¤ Martin J. Heslin, MD ¶ Cancer Institute The University of Texas M. D. University of Alabama at Anderson Cancer Center Birmingham Comprehensive Leonard Saltz, MD † Cancer Center Memorial Sloan-Kettering Cancer Al B. Benson, III, MD † Center Robert H. Lurie Comprehensive Fouad Kandeel, MD Cancer Center of Northwestern City of Hope Cancer Center David E. Schteingart, MD ð University University of Michigan Anne Kessinger, MD † Comprehensive Cancer Center David Byrd, MD ¶ UNMC Eppley Cancer Center at The Fred Hutchinson Cancer Research Nebraska Medical Center Manisha H. Shah, MD † Center/Seattle Cancer Care Alliance Arthur G. James Cancer Hospital & Matthew H. Kulke, MD † Richard J. Solove Research Gerard M. Doherty, MD ¶ Dana-Farber/Partners CancerCare Institute at The Ohio State University of Michigan Comprehensive University Cancer Center Larry Kvols, MD † H. Lee Moffitt Cancer Center & Stephen Shibata, MD † Paul F. Engstrom, MD † Research Institute at the University City of Hope Cancer Center Fox Chase Cancer Center of South Florida David S. Ettinger, MD † John A. Olson, Jr., MD, PhD ¶ The Sidney Kimmel Comprehensive Duke Comprehensive Cancer Cancer Center at Johns Hopkins Center * Writing Committee Member ¶ Surgery/Surgical oncology † Medical oncology ¤ Gastroenterology ð Endocrinology Continue Version 1.2007, 03/14/07 © 2007 National Comprehensive Cancer Network, Inc. -
Psi Technical Specs V31.Pdf
AHRQ Quality Indicators Patient Safety Indicators: Technical Specifications Department of Health and Human Services Agency for Healthcare Research and Quality http://www.qualityindicators.ahrq.gov March 2003 Version 3.1 (March 12, 2007) AHRQ Quality Indicators Web Site: http://www.qualityindicators.ahrq.gov Table of Contents About the Patient Safety Indicators ............................................................................................................... 1 Patient Safety Indicators – Detailed Definitions ............................................................................................ 3 Complications of Anesthesia (PSI 1) ............................................................................................................ 3 Death in Low-Mortality DRGs (PSI 2) ........................................................................................................... 5 Decubitus Ulcer (PSI 3) ................................................................................................................................. 7 Failure to Rescue (PSI 4) .............................................................................................................................. 9 Foreign Body Left during Procedure, Secondary Diagnosis Field (PSI 5 and 21)...................................... 17 Iatrogenic Pneumothorax, Secondary Diagnosis Field (PSI 6 and 22)....................................................... 18 Selected Infections Due to Medical Care, Secondary Diagnosis Field (PSI 7 and 23) ............................. -
Pituitary Apoplexy After Subtotal Thyroidectomy In
CASE REPORT Pituitary Apoplexy after Subtotal Thyroidectomy in an Acromegalic Patient with a Large Goiter Kazunobu Kato, Masakazu Nobori*, Yoshihiro Miyauchi, Motoki Ohnisi, Shyoji Yoshida, Shigeru Oya**, Shin Tomita** and Tomoshige Kino*** A case of pituitary apoplexy occurring after subtotal thyroidectomy in an acromegalic woman with a large adenomatous goiter is described. The patient had severe apnea because the large goiter was causing airway compression. Prior to the planned hypophysectomy, a subtotal thyroidectomy was performed to relieve tracheal stenosis. Shortly after the operation, the patient developed a headache that lasted for several days. The serum levels of growth hormoneand somatomedin-C spontaneously normalized seventeen days after this episode and have remained normal for two years. Pituitary apoplexy was thought to have caused the observed results without deterioration of the pituitary function. (Internal Medicine 35: 472-477, 1996) Key words: acromegaly, thyroid goiter, airway obstruction, diabetes mellitus Introduction and noticed enlargement of her hands. In February 1991, thirst and general fatigue developed and she consulted a local physi- Pituitary apoplexy is an uncommonevent, sometimes fatal, cian and was found to have diabetes mellitus and an abnormal but sometimes it induces complete reversal of acromegaly. It mass adjacent to the right side of the trachea, according to chest occurs in various situations, such as during the course of drug X-ray films. The patient, an unmarried desk clerk, was referred therapy for pituitary adenoma,during pregnancy, or after to us, with the complaint ofdyspnea that was moresevere lying cholecystectomy. However,there are no reports documenting down than in the sitting position. She had excessive nocturnal pituitary apoplexy after thyroidectomy. -
Prediction of Readmission and Complications After Pituitary Adenoma Resection Via the National Surgical Quality Improvement Program (NSQIP) Database
Open Access Original Article DOI: 10.7759/cureus.14809 Prediction of Readmission and Complications After Pituitary Adenoma Resection via the National Surgical Quality Improvement Program (NSQIP) Database Joshua Hunsaker 1 , Majid Khan 2 , Serge Makarenko 1 , James Evans 3 , William Couldwell 1 , Michael Karsy 1 1. Neurological Surgery, University of Utah, Salt Lake City, USA 2. Medicine, Reno School of Medicine, University of Nevada, Reno, USA 3. Neurosurgery, Thomas Jefferson Medical College, Philadelphia, USA Corresponding author: Michael Karsy, [email protected] Abstract Introduction Pituitary adenomas are common intracranial tumors (incidence 4:100,000 people) with good surgical outcomes; however, a subset of patients show higher rates of perioperative morbidity. Our goal was to identify risk factors for postoperative complications or readmission after pituitary adenoma resection. Methods We undertook a retrospective cohort study of patients who underwent surgery for pituitary adenoma in 2006-2018 by using the National Surgical Quality Improvement Program database. The main outcome measures were patient complications and the 30-day readmission rate. Results Among the 2,292 patients (mean age 53.3±15.9 years), there were 491 complications in 188 patients (8.2%). Complications and 30-day readmission have remained stable over time rather than declined. Unplanned readmission was seen in 141 patients (6.2%). Multivariable analysis demonstrated that hypertension (OR=1.6; 95% CI= 1.1, 2.1; p=0.005) and high white blood cell count (OR=1.08; 95% CI=1.03, 1.1; p=0.0001) were independent predictors of complications. Return to the operating room (OR=5.9, 95% CI=1.7, 20.2, p=0.0005); complications (OR=4.1, 95% CI=1.6, 10.6, p=0.004); and blood urea nitrogen (OR=1.08, 95% CI=1.02, 1.2, p=0.02) were independent predictors of 30-day readmission. -
Complete Thesis
University of Groningen Hydrocortisone dose in adrenal insufficiency Werumeus Buning, Jorien IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below. Document Version Publisher's PDF, also known as Version of record Publication date: 2017 Link to publication in University of Groningen/UMCG research database Citation for published version (APA): Werumeus Buning, J. (2017). Hydrocortisone dose in adrenal insufficiency: Balancing harms and benefits. Rijksuniversiteit Groningen. Copyright Other than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons). Take-down policy If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim. Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons the number of authors shown on this cover page is limited to 10 maximum. Download date: 26-09-2021 HYDROCORTISONE DOSE IN ADRENAL INSUFFICIENCY Balancing harms and benefits Jorien Werumeus Buning Hydrocortisone dose in adrenal insufficiency Balancing harms and benefits Thesis, University of Groningen, the Netherlands Cover-design: Machteld Hardick – www.mhardick.nl Lay-out: Ridderprint BV – www.ridderprint.nl Printing: Ridderprint BV – www.ridderprint.nl ISBN: 978-90-367-9699-6 (printed) 978-90-367-9698-9 (eBook) Copyright © 2017 Jorien Werumeus Buning All rights reserved. -
Icd-9-Cm (2010)
ICD-9-CM (2010) PROCEDURE CODE LONG DESCRIPTION SHORT DESCRIPTION 0001 Therapeutic ultrasound of vessels of head and neck Ther ult head & neck ves 0002 Therapeutic ultrasound of heart Ther ultrasound of heart 0003 Therapeutic ultrasound of peripheral vascular vessels Ther ult peripheral ves 0009 Other therapeutic ultrasound Other therapeutic ultsnd 0010 Implantation of chemotherapeutic agent Implant chemothera agent 0011 Infusion of drotrecogin alfa (activated) Infus drotrecogin alfa 0012 Administration of inhaled nitric oxide Adm inhal nitric oxide 0013 Injection or infusion of nesiritide Inject/infus nesiritide 0014 Injection or infusion of oxazolidinone class of antibiotics Injection oxazolidinone 0015 High-dose infusion interleukin-2 [IL-2] High-dose infusion IL-2 0016 Pressurized treatment of venous bypass graft [conduit] with pharmaceutical substance Pressurized treat graft 0017 Infusion of vasopressor agent Infusion of vasopressor 0018 Infusion of immunosuppressive antibody therapy Infus immunosup antibody 0019 Disruption of blood brain barrier via infusion [BBBD] BBBD via infusion 0021 Intravascular imaging of extracranial cerebral vessels IVUS extracran cereb ves 0022 Intravascular imaging of intrathoracic vessels IVUS intrathoracic ves 0023 Intravascular imaging of peripheral vessels IVUS peripheral vessels 0024 Intravascular imaging of coronary vessels IVUS coronary vessels 0025 Intravascular imaging of renal vessels IVUS renal vessels 0028 Intravascular imaging, other specified vessel(s) Intravascul imaging NEC 0029 Intravascular