OPCML Antibody (R30300)

Catalog No. Formulation Size

R30300 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug Bulk quote request

Availability 1-3 business days

Species Reactivity Human, Mouse, Rat

Format Antigen affinity purified

Clonality Polyclonal (rabbit origin)

Isotype Rabbit IgG

Purity Antigen affinity

Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal

UniProt Q14982

Applications Western blot : 0.5-1ug/ml IHC (FFPE) : 0.5-1ug/ml

Limitations This OPCML antibody is available for research use only.

Western blot testing of OPCML antibody and rat brain tissue lysate IHC-P: OPCML antibody testing of human breast cancer tissue

Description Opioid-binding protein/cell adhesion molecule-like(OPCML),(also called opioid-binding cell adhesion molecule(OBCAM). OPCML is a member of the IgLON family of immunoglobulin(Ig) domain-containing glycosylphosphatidylinositol(GPI)-anchored cell adhesion molecules, as an excellent candidate for the 11q25 ovarian cancer TSG in EOC. The OPCML gene comprises 7 exons, spans approximately 600 kb, and is transcribed from telomere to centromere . And due to the lack of transmembrane domains necessary for signal transduction, it is improbable that OBCAM acts independently as an opioid receptor; more likely, it plays an important accessory role in opioid receptor function.

Application Notes The stated application concentrations are suggested starting amounts. Titration of the OPCML antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen An amino acid sequence from the C-terminus of human OPCML (YTCVATNKLGNTNASITLY) was used as the immunogen for this OPCML antibody (100% homologous in human, mouse and rat).

Storage After reconstitution, the OPCML antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.