Since discovered as the first First Von Behring-Röntgen enormous progress in the research Symposium on basic mechanisms of neurotransmission and its clinical significance has been achieved. Distinguished neuroscientists address key issues of today’s concepts of neurotransmission and present their visions for the future in the light of the rising challenge of neurologi- Neurotransmission cal disease. then, now and tomorrow

- The lessons of Loewi - Scientific Organizers: L. Eiden, W. Kummer and E. Weihe

Marburg is located 100 km north of Frankfurt (Main), train connection from the airport: 1 hour, 15 min.

Do you have any questions?

Professor Eberhard Weihe, MD Otto Loewi Vice-Dean of the Faculty of Medicine (1873-1961) of the Philipps-University Marburg Baldinger Straße th th D-35032 Marburg (Germany) November 18 / 19 , 2009

Phone: (+49 6421) 28-66247 (Office) Aula der Alten Universität Marburg or (+49 6421) 28-66248 (Secretary) (Germany) Fax: (+49 6421) 28-68965 Lahntor 3 E-Mail: [email protected]

Professor Eberhard Weihe, MD Vice-Dean of the Faculty of Medicine Marburg of the Philipps-University Baldingerstrasse D-35032 Marburg Further information: Sponsored by:

www.br-stiftung.de/aktuelles

November 18th, 2009 November 19th, 2009 Name: 10:00-11.00 a.m. Opening 09:00 a.m.- 01:00 p.m. Morning session with coffee break

Welcome: Lectures by the international scientific speakers (talks will be abou t 45 min. including questions) Prof. Dr. Joachim- Felix Leo nhard Street: President of the Von Behring-Röntgen-Foundation Reinhard Jahn (Max-Planck-Institute Göttingen) The composition and function of the secretory vesicle Prof. Dr. Volker Nienhaus President of the Philipps-University Marburg Jürgen Wess (National Institute for Mental Health, Bethesda) Postal Code and City: Sensing the “vagusstoff” : muscarinic receptors Prof. Dr. Matthias Rothmund Dean of the Faculty of Medicine, Philipps-University Marburg Jeffrey Erickson (Louisiana State University, New Orleans) Prof. Dr. Trinad Chakraborty Vesicular transporter regulation-- a means Dean of the Faculty of Medicine, Justus-Liebig-University Giessen to control quantal content at Phone: Egon Vaupel Mary Kennedy (California Institute of Technolog y, Pasadena) Mayor of the City of Marburg The function of the postsynaptic density in synaptic plastici ty seen through a computational microscope

Address to the Conference: Lee Eiden (National Institute for Mental Health, Bethesda) E-Mail: A representative of the State of Hesse Cholinergic-peptidergic co-transmission

in the peripheral nervous system 12:00 noon Refreshments and Reception of Participants

Jeffrey Lichtman (Harvard University, Cambridge) 01:00-06:30 p.m. Scientific Lectures with coffee break Imaging synaptic connectivity and dynamics

Introduction to the Scientific Lectures: 01:00-2:00 p.m. Light lunch Eberhard Weihe and Wolfgang Kummer O I will attend the symposium with ______persons th 02:00-06:00 Afternoon session with coffee break (no fees, registration latest October 31 , 2009) Lectures by the international scientific speakers

(talks will be about 45 min. including questions) Lectures by the international scientific speakers Floyd Bloom (Scripps Research Institut e, La Jolla) (talks will be about 45 min. including questions) O I will not attend the symposium

The neurotransmitter concept and its evolution Wolfram Schultz (University of Cambridge, Cambridge) Wolfgang Kummer (Justus-Liebig-University, Giessen) O I will attend the castle dinner (50 €) Reward and movement - two distinct behavioural functions How it began: Pre-neuronal acetylcholine for (Early registration recommended because of limited space)

Eberhard Weihe (Philipps University, Marburg) Bai Lu (GlaxoSmithKline, R&D, Shanghai) Traveling in Loewi’s footsteps - from the heart to the brain BDNF, synaptic plasticity and cognitive function O I will not attend the castle dinner Geoffrey Burnstock (Autonomic Neuroscience Center, London) and dysfunction: role of p75NTR and cholinergic transmission

How ATP became a neurotransmitter Hermona Soreq (Hebrew University, Jerusalem) Tomas Hökfelt (Karolinska Institutet, Stockholm) The cholinergic nervous system and stress

Neuropeptides, companions of classical transmitters Peter Seeburg (Max-Planck-Institute Heidelberg) Julian Thayer (Ohio State University, Columbus) Dissecting memory and its mechanisms at the glutamate receptor

Transmission to the heart reveals the state of the mind Thomas C. Südhof (Stanford University, San Francisco)

Neurotransmission-what do we know, what do we want to know, 07:30-09:00 p.m. Public Celebration where do we go now? Greetings by Prof. Dr. Joachim-Felix Leonhard President of the von Behring-Röntgen-Foundation 07:30 p.m. Reception and Gala Dinner, Fürstensaal of Marburg Castle Presentation of Von Behring-Röntgen Young Investigators Research Awards, preceded and followed by musical selections Dinner speech will be given by Prof. Dr. Joachim-Felix Leonhard, ^ President of the Von Behring-Röntgen-Foundation Otto Loewi Honorary Lecture by Prof. Dr. Konrad Löffelholz (Johannes-Gutenber g-University Mainz)