PLATFORM SESSIONS 25 Program number is in bold above the title. The first author is the presenter. Abstracts begin on page 79.

Thursday, March 30: 4:30 pm–6:30 pm 7 - 6:00 Ballroom of the Americas A-C An essential meiotic function for the INCENP chromosome passenger protein in sister-chromatid cohesion. Tamar 1 2 3 Cell Division and Growth Control Resnick , David Satinover , Fiona MacIsaac , Todd Stukenberg2, William Earnshaw3, Terry Orr-Weaver1, Mar Moderator: Thomas Neufeld, University of Minnesota, Carmena3. 1) Whitehead Institute and Dept Biology, MIT, Minneapolis Cambridge, MA; 2) University of Virginia, Dept Biochemistry and Molecular Genetics, Charlottesville, VA; 3) Wellcome Trust Centre for Cell Biology, School of Biology, University of 1 - 4:30 Edinburgh, Edinburgh, UK. Drosophila TCTP Regulates Cell Growth and Proliferation by Acting as a Guanine Nucleotide Exchange Factor for the Rheb 8 - 6:15 GTPase. Ya-Chieh Hsu1, Joshua Chern2, Yi Cai3, Mingyao Mutation of corona reveals an SC-independent role for C(3)G Liu3, Kwang-Wook Choi1,2,4. 1) Program in Developmental in maintaining meiotic chromosome pairing. Scott L. Page, R. Biology, Baylor College of Medicine; 2) Department of Scott Hawley. Stowers Institute for Medical Research, Kansas Molecular and Cellular Biology, Baylor College of Medicine; City, MO. 3) Department of Medical Biochemistry and Genetics, Alkek Institute of Biosciences and Technology, Texas A&M University System Health Science Center; 4) Department of Ophthalmology, Baylor College of Medicine Houston, TX.

2 - 4:45 The tumor suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis. Fisun Hamaratoglu1,2, Maria Willecke1, Madhuri Kango-Singh1, Riitta Nolo1, Georg Halder1,3. 1) Dept Biochem & Molec Biol, MD Anderson Cancer Ctr, Houston, TX; 2) Prog in Developmental Biology, Baylor College of Medicine, Houston, TX; 3) Prog in Genes and Development, University of Texas M. D. Anderson Cancer Ctr, Houston, TX.

3 - 5:00 Phosphorylation and activity of the tumor suppressor Merlin and the ERM protein Moesin are co-ordinately regulated by the SLIK kinase. Sarah C. Hughes, Richard G. Fehon. Depart. Mol. Gen. and Cell Bio., University of Chicago, Chicago, IL.

4 - 5:15 The growth regulator dMyc functions in part independently of dMax. Dominik D. Steiger1, Sarah Pierce2, Robert N. Eisenman2, Peter Gallant1. 1) Zoological Institute, University of Zurich, Zurich, Switzerland; 2) Fred Hutchinson Cancer Research Center, Division of Basic Sciences, Seattle, WA.

5 - 5:30 Identification of genes required for Myc-induced cell growth. Julie Secombe, Leni Carlos, Robert Eisenman. Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA.

6 - 5:45 The Drosophila condensin subunit CapH2 ensures faithful separation of male meiotic chromosomes. Tom Hartl, Sarah Sweeney, Paula Campbell, Giovanni Bosco. Dept Molec & Cellular Biol, Univ Arizona, Tucson, AZ. 26 PLATFORM SESSIONS Program number is in bold above the title. The first author is the presenter. Abstracts begin on page 79.

Thursday, March 30: 4:30 pm–6:30 pm Thursday, March 30: 4:30 pm–6:30 pm Ballroom of the Americas D-F Lanier Grand Ballroom A-B

Evolution and Quantitative Genetics Neurogenetics and Neural Development Moderator: Greg Gibson, North Carolina State University, Moderator: Kwang-Wook Choi, Baylor College of Raleigh Medicine, Houston, Texas

9 - 4:30 17 - 4:30 Joint estimates of the effects and frequencies of QTL using Non-Canonical signaling of BMP ligands through an Activin- synthetic recombinant populations of Drosophila. Stuart J. type pathway regulates brain lobe development and 1 Macdonald, Anthony D. Long. Dept. Ecology & Evolution, photoreceptor axon targeting in Drosophila. Changqi C. Zhu , 1,2 1,2 University of California, Irvine, CA. Osamu Shimmi , Michael B. O’Connor . 1) Dept of Genetics, Cell Biology and Development, University of Minnesota, 6-160 Jackson Hall, Minneapolis, MN 55455; 2) 10 - 4:45 Howard Hughes Medical Institute, University of Minnesota, 6- Population genetic analyses of a thermal QTL in experimental 160 Jackson Hall, Minneapolis, MN 55455. and natural populations of D. melanogaster. David Rand1, Colin Meiklejohn1, Donna Folk2, Reid Hopkins1, Daniel 18 - 4:45 Solomon1, Daniel Weinreich1, George Gilchrist2. 1) Ecology The novel secreted glial factor Tangled interacts with the Robo & Evolutionary Biol, Brown Univ, Providence, RI; 2) Department receptors to position longitudinal axon tracts in the embryonic of Biology, William and Mary, Williamsbug, VA. nervous system. Tirtha K. Das, Dan Leaman, Ulrike Gaul. Developmental Neurogenetics, Rockefeller University, New 11 - 5:00 York, NY. Tales from the X files: chromosomal context, dosage compensation, and gene expression. Marta Wayne1, Marina 19 - 5:00 Telonis-Scott1, Lisa Bono2, Lawrence Harshman3, Artyom Dendrite Morphogenesis: Role of cytoskeletal molecule, Diaphanous. Madhuri Shivalkar, Gaia Tavosanis. Molecular Kopp4, Sergey Nuzhdin4, Lauren McIntyre2. 1) Zoology, Neurobiology, Max Planck Institute of Neurobiology, Munich, University of Florida, Gainesville, FL; 2) Agronomy, Purdue Germany. University, W. Lafayette, IN; 3) School of Biological Sciences, U. Nebraska, Lincoln, NE; 4) Evolution and Ecology, UC Davis, 20 - 5:15 Davis, CA. A novel POU gene acts in odor receptor gene choice. Andrea L. Tichy, Anandasankar Ray, John R. Carlson. MCDB, Yale 12 - 5:15 University, New Haven, CT. Role of Natural Selection in the Evolution of Gene Expression. Alisha K. Holloway1, Jason G. Mezey2, Corbin D. Jones3. 1) 21 - 5:30 Evolution & Ecology, Univ California-Davis, Davis, CA; 2) Rumi, a protein with homology to bacterial polysaccharide Biological Statistics, Cornell University, NY; 3) Department of modifiers, is a general regulator of Notch signaling in 1,5 2,5 Biology, University of North Carolina-Chapel Hill, Chapel Hill, Drosophila. Hamed Jafar-Nejad , Melih Acar , Akhila Rajan1, Vafa Bayat3, Dafina Ibrani1, Hongling Pan1, Hugo NC. Bellen1,2,3,4. 1) Department of Molecular & Human Genetics; 2) Program in Developmental Biology; 3) Medical Scientist 13 - 5:30 Training Program; 4) Howard Hughes Medical Institute, Baylor Evolutionary modification of Hox-free dorsal appendages in College of Medicine, Houston, TX 77030; 5) equal contribution. a beetle Tribolium castaneum. Yoshinori Tomoyasu, Robin E. Denell. Div Biol, Kansas State Univ, Manhattan, KS. 22 - 5:45 Numb regulates R3/R4 specification and the establishment 14 - 5:45 of planar cell polarity in the Drosophila eye. Pedro Domingos, The genetic architecture of hybrid male sterility. Laura Reed, Hermann Steller, Bertrand Mollereau. Steller Laboratory, Brooke LaFlamme, Therese Markow. Dept EEB, Univ Arizona, Rockefeller Univ, New York, NY. Tucson, AZ. 23 - 6:00 15 - 6:00 Roles for the Tumor Suppressor Genes Adenomatous Polyposis Coli 1 and 2 in Cell Adhesion and Axon Outgrowth An HP1 interacting protein causes hybrid lethality between D. in the Developing Larval Brain. Melissa Hayden, Kathryn melanogaster and D. simulans. Daniel A. Barbash, Nicholas Akong, Mark Peifer. Curriculum in Genetics, University of J. Brideau, Jun Wang, Heather A. Flores, Adam G. Diehl, North Carolina, Chapel Hill, NC. Shamoni Maheshwari. Dept Molecular Biol & Genetics, Cornell Univ, Ithaca, NY.

16 - 6:15 Molecular population genetics of incipient speciation. Anthony Greenberg, Joshua Shapiro, Hurng-Yi Wang, Chung-I Wu. Dept Ecology & Evolution, The University of Chicago, Chicago, IL. PLATFORM SESSIONS 27 Program number is in bold above the title. The first author is the presenter. Abstracts begin on page 79.

24 - 6:15 Friday, March 31: 8:30 am–10:15 am Discovery and Characterization of Genes involved in de novo Lanier Grand Ballroom A-B formation of Drosophila NMJs. Ghulam M. Lone1, Zoltan Asztalos2, Richard Auburn2, Wolfgang Bottenberg1, Richard Kammerer1, Cahir O’Kane2, João Rocha2, Sean T. Sweeney3, Cytoskeleton and Cellular Biology Mingyao Yang4, Andreas Prokop1. 1) Faculty of Lifesciences, Univ. Manchester; 2) Department of Genetics, Univ. Cambridge, Moderator: David Bilder, University of California-Berkeley UK; 3) University of York, York, UK; 4) MRC Dunn Human Nutrition Unit, Wellcome Trust/MRC Building, Cambridge, UK. 25 - 8:30 The lipid droplet proteome: droplets as a storage depot. Michael Welte1, Silvia Cermelli2, Yi Guo1, Steven Gross2. 1) Brandeis Univ, Waltham, MA; 2) University of California, Irvine, CA.

26 - 8:45 Fragile X mental retardation protein 1 (FMR1) is required for Drosophila cellularization. O. Papoulas, K. Monzo, Y. Wang, J. C. Sisson. The Section of MCD Biology and The Insitute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX.

27 - 9:00 Identification of genes involved in integrin-mediated cell spreading. Klodiana Jani, Frieder Schöck. Stewart Biology Building, McGill University, Montreal, Quebec, Canada.

28 - 9:15 The Role of Canoe in Morphogenesis. Jessica K. Sawyer1, Ulrike Gaul2, Mark Peifer1. 1) Dept Biol, Univ North Carolina, Chapel Hill, NC; 2) Laboratory of Developmental Neurogenetics, Rockefeller Univ, NY.

29 - 9:30 A screen for epithelial defects in the Drosophila ovary reveals a role for cytoplasmic Dynein in the targeting of apical proteins. Sally Horne-Badovinac, David Bilder. Department of Molecular & Cell Biology, University of California, Berkeley, Berkeley, CA.

30 - 9:45 Kelch Functions with Cullin3 to Remodel F-Actin in Ovarian Ring Canals. Andrew Hudson, Lynn Cooley. Yale Univ School of Medicine, New Haven, CT.

31 - 10:00 Function of DExo84 in maintenance of adherens junctions and apical identity in epithelial cell polarity. James Blankenship1, Margaret Fuller2, Jennifer Zallen1. 1) Dept Developmental Biol, Sloan-Kettering Institute, New York, NY; 2) Dept Developmental Biol, Stanford University, Stanford, CA. 28 PLATFORM SESSIONS Program number is in bold above the title. The first author is the presenter. Abstracts begin on page 79.

Friday, March 31: 8:30 am–12:45 pm 38 - 10:00 Ballroom of the Americas D-F gfA is a nicotinic acetylcholine receptor required for an escape behavior in Drosophila. Amir Fayyazuddin1, Mahira Neural Physiology and Behavior A. Zaheer1, P. Robin Hiesinger1, 2, Hugo J. Bellen1, 2. 1) Molecular and Human Genetics, Baylor College of Medicine, Moderator: J. Troy Littleton, Massachusetts Institute of Houston, TX; 2) HHMI. Technology, Cambridge 10:15 - Break 32 - 8:30 Memory trace in Drosophila DPM neurons. Dinghui Yu1, Alex 39 - 10:45 C. Keene2, Anjana Srivatsan3, Scott Waddell2, Ronald L. Multimodal Sensory Integration in the Control of Rapid Flight Davis1,4. 1) Department of Molecular and Cellular Biology, Maneuvers. John A. Bender, Michael H. Dickinson. Division Baylor College of Medicine, Houston, TX ; 2) Department of of Biology, California Institute of Technology, Pasadena, CA Neurobiology, University of Massachusetts, Worcester, MA 91125. 01605; 3) Department of Human and Molecular Genetics; 4) Department of Psychiatry and Behavioral Sciences, Baylor 40 - 11:00 College of Medicine, Houston, TX 77030. BiP expression levels affect recovery sleep in Drosophila. Nirinjini Naidoo, Vincent Casiano, John Zimmerman, Allan 33 - 8:45 Pack. Center for Sleep, University of Pennsylvania, Activity of the neurogenic protein NEURALIZED is required Philadelphia, PA. for Learning and Long-Term Memory formation. Efthimios Skoulakis, Elias Pavlopoulos. Institute of Molecular Biology 41 - 11:15 & Genetics, BSRC Alexander Fleming, Vari, Greece. Crossmodal integration of olfaction and taste. Takashi Shiraiwa, Wynand Van der Goes van Naters, John Carlson. 34 - 9:00 Department of Molecular, Cellular and Developmental Biology, Discrimination learning changes the perception of odor Yale Univ., New Haven, CT. intensity but not odor identity in Drosophila. Shouzhen Xia, Tim Tully. Cold Spring Harbor Laboratory, 1 Bungtown Road, 42 - 11:30 Cold Spring Harbor, NY 11724. Drosophila Homer Is Required in Neurons of the Ellipsoid Body and Pars Intercerebralis for Normal Ethanol Sensitivity 35 - 9:15 and Tolerance. Nancy Urizar1, Zhiyong Yang1, Howard Neurofibromatosis type 1 is involved in both learning and Edenberg2, Ronald Davis1,3. 1) Department of Molecular & memory processes. Ivan S. Ho1, Frances Hannan2, Inessa Cellular Biology, Baylor College of Medicine, Houston, TX; 2) Hakkar1, Yi Zhong1. 1) Zhong Lab, Cold Spring Harbor Center for Medical Genomics, Indiana University School of Laboratory, Cold Spring Har, NY; 2) Department of Cell Medicine, Indianapolis, Indiana, 46202; 3) Department of Biology, New York Medical College, Valhalla, NY 10595. Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX. 36 - 9:30 A Command Chemical Triggers an Innate Behavior by 43 - 11:45 Sequential Activation of Multiple Peptidergic Ensembles in Homeostatic transcriptional regulation of the slowpoke the CNS. Young-Joon Kim1, Dusan Zitnan2, C. Giovanni channel gene during drug tolerance modulates neural Galizia1, Kook-Ho Cho1, Michael Adams1. 1) Depts of excitability. Alfredo Ghezzi, Jascha Pohl, Yazan Al-Hasan, Entomology and Cell Biology & Neuroscience, University of Nigel Atkinson. Sect Neurobiology, Univ Texas, Austin, Austin, California, Riverside, CA; 2) Institute of Zoology, Slovak TX. Academy of Sciences, Bratislava, Slovakia. 44 - 12:00 37 - 9:45 fruitless is necessary for masculine patterns of aggressive Reactive oxygen species-sensitive class IV multiple dendritic behavior and masculine territorial behavior. Steven Nilsen, neurons coordinate larval growth and developmental timing Edward Kravitz. Dept Neurobiology, Harvard Medical School, of neuroendocrine signaling. Joshua A. Ainsley1, Myung- Boston, MA. Jun Kim2, Lauren J. Wegman1, Janette M. Pettus1, Wayne A. Johnson1,2. 1) Dept Physiology/Biophysics, Univ Iowa, 45 - 12:15 The Drosophila Bruchpilot protein is required for presynaptic Iowa City, IA; 2) Neuroscience PhD Program. active zone assembly and calcium-channel clustering to ensure high vesicle release probability. Stephan Sigrist1, Erich Buchner2, Carolin Wichmann1, Manuela Schmidt1, Robert Kittel1. 1) European Neuroscience Institute Goettingen, Goettingen, Germany; 2) Lehrstuhl für Genetik und Neurobiologie, Am Hubland, Würzburg, Germany. PLATFORM SESSIONS 29 Program number is in bold above the title. The first author is the presenter. Abstracts begin on page 79.

Friday, March 31: 8:30 am–10:15 am Friday, March 31: 10:45 am–12:45 pm Ballroom of the Americas A-C Ballroom of the Americas A-C

Signal Transduction Genome and Chromosome Structure Moderator: Xinhua Lin, Children’s Hospital Medical Moderator: Pamela Geyer, University of Iowa, Iowa City Center, Cincinnati, OH 53 - 10:45 46 - 8:30 ARGONAUTE-1 accumulates locus specific long siRNA Properties and components of the Drosophila BMP-signaling required for building histone code of condensed chromatin. pathway. George Pyrowolakis1, Ute Nussbaumer1, Alex Utpal Bhadra1, S. N. C. V. Lakshmi Pushpavalli1, Weiss1, Kerstin Bartscherer2, Michael Boutros2, Markus Krishnamohan Parsi2, Maheshwar Reddy1, Manika Pal Affolter1. 1) Dept of Cell Biology, Biozentrum, University Basel, Bhadra2. 1) Functional Genomics & Gene Silencing Group, Basel, Switzerland; 2) Signaling and Functional Genomics, Centre for Cellular & Molecular Biology, Hyderabad 500007, German Cancer Research Center, Heidelberg, Germany. India; 2) Department of Chemical Biology, Indian Institute of Chemical Technology, Uppal Road, Hyderabad 500007, India. 47 - 8:45 Regulation of Wingless secretion and signaling by sprinter. 54 - 11:00 Erica M. Selva1, Robyn Goodman1, Shreya Thombre1, Dione Regulation of transcription and chromatin structure by Gray1, Zeynep Firtina1, Eric Spana2, Jamie Roebuck2, Poly(ADP-ribose) Polymerase. Alexei Tulin, Ammini Menon, Norbert Perrimon3. 1) Biological Sciences, University of Natalia Naumova. Basic Science, Fox Chase Cancer Center, Delaware, Newark, DE; 2) Model System Genomics, Duke Philadelphia, PA. University, Durham, NC; 3) Department of Genetics, Harvard Medical School, Boston MA. 55 - 11:15 Boundary swapping between Fab-8 and Fab-7 within the 48 - 9:00 bithorax complex. Carole Iampietro, François Karch. Zoology Wnt and Hh Signaling and Polarity in the Drosophila Embryo. and Animal Biology, University of Geneva , Geneva, GE, Nicholas Tolwinski, Jennifer Zallen. Developmental Biology, Switzerland. Sloan-Kettering Institute, New York, NY. 56 - 11:30 49 - 9:15 Polycomb regulation in Drosophila: a genomewide view. Yuri Internalization is required for proper Wingless signaling in B. Schwartz, Tatyana G. Kahn, Vincenzo Pirrotta. Mol. Biol. Drosophila. Elaine S. Seto1, Hugo J. Bellen1,2. 1) Program in and Biochem., Rutgers University, Piscataway, NJ. Developmental Biology, Baylor College of Medicine, Houston, TX; 2) HHMI, Dept. of Molecular and Human Genetics, Baylor 57 - 11:45 College of Medicine, Houston, TX. The JIL-1 histone H3S10 kinase regulates heterochromatic spreading and gene silencing in Drosophila. Huai Deng, 50 - 9:30 Xiaomin Bao, Weiguo Zhang, Stephanie Lerach, Jack Girton, The role of Patched C terminal domain in Hedgehog signaling. Jorgen Johansen, Kristen Johansen. Biochem, Biophys & Xingwu Lu, Thomas Kornberg. Dept Biochemistry, Univ Mol Biology, Iowa State University, Ames, IA. California, San Francisco, San Francisco, CA. 58 - 12:00 51 - 9:45 The putative Drosophila transcription factor Woc is required The novel SAM domain protein Aveugle is required for Raf to prevent telomeric fusions. Giovanni Cenci1, Grazia D. Raffa2, activation in the Drosophila EGF receptor signaling pathway. 4, Giorgia Siriaco2, 5, Michael L. Goldberg3, Maurizio Gatti2. 1) Jean-Yves Roignant1, Sophie Hamel2, Florence Janody3, DISTeBA, Univ Lecce-Ecotekne, Lecce, Italy; 2) Dipartimento Jessica Treisman1. 1) Skirball Institute of Biomolecular di Genetica e Biologia Molecolare and Istituto di Biologia e Medicine and Department of Cell Biology, New York University Patologia Molecolari del CNR, Universitá “La Sapienza”, School of Medicine; 2) Ecole Normale Supérieure, CNRS 00185 Rome, Italy; 3) Department of Molecular Biology and UMR8542, Paris, France; 3) Institut de Biologie du Genetics, Cornell University, Ithaca, NY 14853-2703; 4) The Développement de Marseille, Campus de Luminy, Marseille, Scripps Research Institute 10550 North Torrey Pines Road France. La Jolla, CA 92037; 5) Molecular Cell and Developmental Biology 309 Sinsheimer Labs University of California, Santa 52 - 10:00 Cruz Santa Cruz, CA 95064. A Basolateral Junction Signaling Pathway Suppresses Normal and Tumor Invasion. Scott Goode1,2,4, Min Zhao1,4, Pshemek 59 - 12:15 Szafranski1,4, Matthew Anderson1,3,4, Chad Hall1,4. 1) Dept. Integration of different histone modification compartments in Pathology; 2) Dept. of Molecular and Human Genetics, the heterochromatic genes. Jiro C. Yasuhara, Kirk N. Okada, Molecular and Cellular Biology, and Program in Barbara T. Wakimoto. Dept Biol, Univ Washington, Seattle, Developmental Biology; 3) Dept. of Obstetrics and Gynecology; WA. 4) Baylor Col Medicine, Houston, TX. 30 PLATFORM SESSIONS Program number is in bold above the title. The first author is the presenter. Abstracts begin on page 79.

Friday, March 31: 10:45 am–12:45 pm 66 - 12:15 Lanier Grand Ballroom A-B Dissecting muscular dystropy in Drosophila. Halyna Shcherbata1, Andriy Yatsenko1,2, Karin Fischer1, Mariya 2 3 1 Drosophila Models of Human Diseases Kucherenko , Uri Nudel , David Baker , Hannele Ruohola- Baker1. 1) Dept Biochemistry, Univ Washington, Seattle, WA; Moderator: Mark Fortini, National Cancer Institute, 2) Ivan Franko Lviv National University, Lviv, Ukraine; 3) The Frederick, Maryland Weizmann Institute of Science, Rehovolt, Izrael. 67 - 12:30 60 - 10:45 Drosophila homologs of FANCD2 and FANCL function in DNA Dramatic CAG repeat instability in a Drosophila polyQ disease repair. Lorri R. Marek, Allen E. Bale. Dept Genetics, Yale Univ, model. Joonil Jung2, Nancy Bonini1, 2. 1) Howard Hughes New Haven, CT. Medical Institute; 2) Department of Biology, University of Pennsylvania, Philadelphia, PA.

61 - 11:00 Light-dependent Retinal Degeneration in trafficking mutants of Drosophila. Yashodhan Chinchore, Patrick Dolph. Biological Sciences, Dartmouth College, Hanover, NH.

62 - 11:15 Genetic Modifiers in Drosophila Reveal Common and Distinct Mechanisms of Pathogenesis among Polyglutamine Diseases. Joana Branco1,2, Ismael Al-Ramahi1, Lubna Ukani1, Alma Pérez1, Pedro Fernandez-Funez1, Diego Rincón-Limas1, Juan Botas1. 1) Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030, USA; 2) Graduate Program in Basic and Applied Biology, Abel Salazar Institute of Biomedical Sciences, University of Porto, 4099-003 Porto, Portugal.

63 - 11:30 Drosophila NMNAT is required to maintain neuronal integrity and its overexpression protects from activity- and Ataxin-1- induced neurodegeneration. Rong Grace Zhai1, 2, Yu Cao2, Peter Robin Hiesinger1, 2, Yi Zhou1, 2, Sunil Q. Mehta3, Karen L. Schulze1, 2, Patrik Verstreken1, 2, 3, Hugo J. Bellen1, 2, 3, 4. 1) Howard Hughes Medical Institute, Baylor College of Medicine, Houston, TX; 2) Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030; 3) Program in Developmental Biology, Baylor College of Medicine, Houston, TX 77030; 4) Department of Neuroscience, Baylor College of Medicine, Houston, TX 77030.

64 - 11:45 xbp1 splicing and Unfolded Protein Response is activated as a protective mechanism in the Drosophila model for the Autosomal Dominant Retinitis Pigmentosa. Hyung Don Ryoo1,2, Pedro Domingos2, Hermann Steller2. 1) Cell Biology, NYU School of Medicine, New York, NY; 2) Steller Laboratory, The Rockefeller University, New York, NY.

65 - 12:00 Pharmacological rescue of a Drosophila model for Fragile X Syndrome. Tom A. Jongens1, Sean M. J. McBride2, Catherine H. Choi3, Yan Wang1, David Liebelt2, Evan Braustein2, David Ferreiro2, Amita Sehgal1, Kathleen K. Siwicki4, Thomas C. Dockendorff5, Hahn T. Nguyen2, Thomas V. McDonald2. 1) Genetics, 7096 Stellar-Chance, Univ Pennsylvania Sch Medicine, Philadelphia, PA; 2) Albert Einstein College of Medicine, Bronx, NY; 3) Drexel University College of Medicine, Philadelphia, PA; 4) Swarthmore College, Swarthmore, PA; 5) Miami University of Ohio, Oxford, OH. PLATFORM SESSIONS 31 Program number is in bold above the title. The first author is the presenter. Abstracts begin on page 79.

Friday, March 31: 4:30 pm–6:30 pm Friday, March 31: 4:30 pm–6:30 pm Ballroom of the Americas A-C Ballroom of the Americas D-F

Physiology and Aging Organogenesis Moderator: Scott Pletcher, Baylor College of Medicine, Moderator: Deborah Jean Andrew, John Hopkins Houston, Texas University School of Medicine, Baltimore, Maryland

68 - 4:30 76 - 4:30 Unraveling how diet restriction extends lifespan: stable isotope The MARVEL domain protein, SINGLES BAR, is required for analysis of nutrient acquisition and allocation. Marc Tatar1, progression past the pre-fusion complex stage of myoblast Kyung-Jin Min1, Diane O’Brien2. 1) Ecology and Evolutionary fusion. Beatriz Estrada1, Anne D. Maeland2, Stephen Biol., Brown University, Providence, RI; 2) Institute of Arctic Gisselbrecht1, Nicholas H. Brown2, Alan M. Michelson1. 1) Biology, University of Alaska, Fairbanks, AK. Division of Genetics, Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA 69 - 4:45 02115; 2) Gurdon Institute and Department of Anatomy, Olfaction and food derived odorants regulate lifespan and University of Cambridge, Cambridge, UK CB2 1QN. metabolism in D. melanogaster. Sergiy Libert1, Scott Pletcher1,2,3. 1) CMB, Baylor College of Medicine, Houston, 77 - 4:45 TX; 2) Huffington Center on Aging, Houston, TX; 3) Molecular Actin remodeling is critical for myoblast fusion. Brian E. and Human Genetics, BCM, Houston, TX. Richardson1, Karen L. Beckett1, Mary K. Baylies1,2. 1) Allied Program in Biochemistry, Molecular and Cell Biology, Weill 70 - 5:00 Graduate School of Medical Sciences of Cornell University, Fatty acid auxotrophy in Drosophila larvae lacking SREBP. New York, NY; 2) Developmental Biology Program, Sloan- Amit Kunte, Krista Matthews, Robert Rawson. Dept of Kettering Institute, New York, NY. Molecular Genetics, University of Texas Southwestern Medical Ctr, Dallas, TX. 78 - 5:00 WNT5 signaling acts through the atypical receptor, DERAILED, 71 - 5:15 to guide salivary gland migration. Katherine E. Harris, Steven Effects of aging on the maintenance of germline stem cells K. Beckendorf. Dept Molecular & Cell Biol, Univ California, and the stem cell niche. Chihunt Wong1, 2, Monica Boyle1, Berkeley, CA. Michael Rocha1, D. Leanne Jones1. 1) Laboratory of Genetics, Salk Institute for Biological Studies, La Jolla, CA; 2) Department 79 - 5:15 of Biological Sciences, University of California - San Diego, The adult Drosophila posterior midgut is maintained by La Jolla, CA. pluripotent stem cells. Benjamin Ohlstein, Allan Spradling. Howard Hughes Medical Institute Research Laboratories, 72 - 5:30 Department of Embryology, Carnegie Institution of The DHR96 nuclear receptor regulates xenobiotic responses Washington, 3520 San Martin Drive, Baltimore, Maryland in Drosophila. Kirst King-Jones, Michael A. Horner, Geanette 21218 USA. Lam, Carl S. Thummel. Howard Hughes Medical Institute, Department of Human Genetics, University of Utah, School of 80 - 5:30 Medicine, 15 N 2030 E Room 5100, Salt Lake City, UT 84112- Genetic dissection of epithelial maturation in trachea by live 5331, USA. imaging. Vasilios Tsarouhas, Kirsten-André Senti, Satish A. Jayaram, Johanna Hemphäla, Christos Samakovlis. 73 - 5:45 Developmental Biology, Stockholm University, Stockholm, Ras activity in the prothoracic gland regulates body size and Sweden. developmental rate via ecdysone release. Philip Caldwell, Magdalena Walkiewicz, Michael Stern. Department of 81 - 5:45 Biochemistry and Cell Biology, Rice University, Houston, TX. Wurst, a novel Hsp70 interactor protein, is essential for tracheal morphogenesis. Matthias Behr1, Christian Wingen1, Birgit 74 - 6:00 Stümpges1, Verena Arndt1, Lara Kutschenko1, Christian The regulation of lifespan by Falafel, a homolog to Suppressor Wolf2, Reinhard Schuh2, Michael Hoch1. 1) Molecular of Map Kinase. Brian T. Sage1, Heinrich Jasper2, Li Qian3, Developmental Biology, University Bonn; 2) Molecular Rolf Bodmer3, Andrew Dillin4, Marc Tatar1. 1) Dept Ecol & Developmental Biology, Max-Planck-Institute Göttingen. Evol Biol, Brown University, Providence, RI; 2) Dept of Biology, University of Rochester, Rochester, NY; 3) Burnham Institute, (continued, next page) La Jolla, CA; 4) Salk Institute, La Jolla, CA.

75 - 6:15 BMP signaling influences nutrient sensing and storage during growth and development. Shannon Ballard, Kristi Wharton. Dept MCB, Brown Univ, Providence, RI. 32 PLATFORM SESSIONS Program number is in bold above the title. The first author is the presenter. Abstracts begin on page 79.

82 - 6:00 Friday, March 31: 4:30 pm–6:30 pm Gliotactin and Dlg form a unique complex at the tricellular Lanier Grand Ballroom A-B junction. Vanessa Auld, Kristi Charish, Jaimmie Que, Sarah Ravn, Joost Schulte. Dept Zoology, Univ British Columbia, Gametogenesis and Sex Determination Vancouver, BC, Canada. Moderator: Richard Kelley, Baylor College of Medicine, 83 - 6:15 Houston, Texas Rac function in epithelial tube morphogenesis. Carolyn Pirraglia, Rakhi Jattani, Monn Monn Myat. Department of 84 - 4:30 Cell & Developmental Biology, Weill Medical College of The eIF4G2 gene is required for meiotic division and Cornell University, New York, NY 10021. differentiation in spermatogenesis. Catherine Baker, Margaret Fuller. Dept Developmental Biol, Stanford Univ Sch Medicine, Stanford, CA.

85 - 4:45 Notch signaling from the Germ Line Stem Cells induces Stem Cell Niche in Drosophila ovary. Ellen Ward, Steven Reynolds, Halyna Shcherbata, Steven Hatfield, Karin Fischer, Hannele Ruohola-Baker. Department of Biochemistry, University of Washington, Seattle, WA 98195.

86 - 5:00 Sex-lethal feminizes neurons required for two female behaviors by acting on gene targets other than transformer. Daniel S. Evans, Thomas W. Cline. Department of Molecular and Cell Biology, University of California-Berkeley, Berkeley, CA. 94720- 3204.

87 - 5:15 Jagunal is required for polarized secretion during Drosophila oogenesis. Sangil Lee, Lynn Cooley. Dept Genetics, Yale Univ, New Haven, CT.

88 - 5:30 Novel Function of Tudor domains in Germline Development and Maintenance of Polar Granule Architecture. Alexey L. Arkov1, Ju-Yu S. Wang1, Andres Ramos2, Ruth Lehmann1. 1) Developmental Genetics Program, HHMI, Skirball Institute at NYU School of Medicine, New York, NY; 2) Molecular Structure Division, National Institute for Medical Research, London.

89 - 5:45 Opposing roles of the EGFR and Rho-type small monomeric GTPases during niche formation. Cordula Schulz, Angshuman Sarkar, Nishita Parikh, Stephen Hearn. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.

90 - 6:00 A nuclear hormone receptor that affects spermathecae number and fertility. Anna E. Krueger1,2, Allan Spradling1,2. 1) Carnegie Institution/HHMI, Baltimore, MD; 2) Johns Hopkins University, Baltimore, MD.

91 - 6:15 Stonewalling germline stem cell differentiation through epigenetic controls. Jean Z. Maines, Joseph K. Park, Dennis M. McKearin. Molecular Biology, UT Southwestern Medical Center, Dallas, TX. PLATFORM SESSIONS 33 Program number is in bold above the title. The first author is the presenter. Abstracts begin on page 79.

Saturday, April 1: 8:30 am–10:30 am 98 - 10:00 Ballroom of the Americas A-C FlyExpress: An image-matching web-tool for finding genes with overlapping patterns of expression in Drosophila embryos. 1 1 Techniques and Genomics Bernard Van Emden , Hector Ramos , Sethuraman Panchanathan2, Stuart Newfeld3,1, Sudhir Kumar1,3, Arizona Moderator: Rui Chen, Baylor College of Medicine, State Univ, Tempe. 1) Biodesign Inst; 2) Department of Houston, Texas Computer Science and Engineering; 3) School of Life Sciences. 92 - 8:30 99 - 10:15 Biological function of unannotated transcription during the BDGP Gene Disruption Project update. Robert W. Levis1, early development of D. melanogaster. J. Robert Manak, Sujit Yuchun He2,3, Joseph W. Carlson4, Martha Evans-Holm4, Soo Dike, Victor Sementchenko, Philipp Kapranov, Jeff Long, Park4, Kenneth H. Wan4, P. Robin Hiesinger2,3, Karen L. Jill Cheng, Ian Bell, Srinka Ghosh, Antonio Piccolboni, Schulze2,3, Roger A. Hoskins4, Allan C. Spradling1,3, Hugo J. Thomas R. Gingeras. AFFY Labs-Transcriptome, Affymetrix, Bellen2,3. 1) Dept Embryology, Carnegie Institution, Baltimore, Santa Clara, CA. MD; 2) Dept Molecular and Human Genetics, Baylor College of Medicine, Houston, TX; 3) Howard Hughes Medical Institute; 93 - 8:45 4) Dept Genome Biology, Lawrence Berkeley National Genome-wide Identification of Direct Targets of the Drosophila Laboratory, Berkeley, CA. Retinal Determination Protein Eyeless. Yumei Li, Edward Ostrin, Kristi Hoffman, Keqing Wang, Graeme Mardon, Rui Chen. Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX.

94 - 9:00 Using Drosophila protein interaction maps to study genetic regulatory networks. Russell Finley1, Stephen Guest1, Maria Cypher1, Kyle Gardenour1, Svetlana Pacifico1,2, Bernardo Mangiola1, Guozhen Liu1, Aleric Soans1, Huamei Zhang1. 1) Ctr Molecular Med & Gen, Wayne State Univ Med Sch, Detroit, MI; 2) Department of Computer Science, Wayne State University.

95 - 9:15 Site-specific transgenesis using the phiC31 integrase. Johannes Bischof, Konrad Basler. Institute of Molecular Biology, NCCR Frontiers in Genetics, University of Zurich, Winterthurerstr. 190, CH-8057 Zurich, Switzerland.

96 - 9:30 P[acman]: A Novel Drosophila Transgenesis Platform to Facilitate In Vivo Structural and Functional Studies of Genes. Koen Venken1, Hugo Bellen1,2. 1) Program in Developmental Biology, Baylor College of Medicine, Houston, TX; 2) HHMI; Department of Molecular and Human Genetics; Baylor College of Medicine, Houston, TX.

97 - 9:45 Berkeley Drosophila Transcription Network Project: 3D blastoderm gene expression atlas. David Knowles1, Cris Luengo Hendriks1, Soile Keränen1, Charless Fowlkes2, Gunther Weber3, Oliver Rübel4, Min-Yu Huang3, Hanchuan Peng1, Angela DePace1, Lisa Simirenko1, Bernd Hamann3, Damir Sudar1, Jitendra Malik2, Mike Eisen1, Mark Biggin1. 1) Lawrence Berkeley National Laboratory; 2) University California, Berkeley; 3) University California, Davis; 4) University Kaiserslautern, Germany. 34 PLATFORM SESSIONS Program number is in bold above the title. The first author is the presenter. Abstracts begin on page 79.

107 - 10:15 Saturday, April 1: 8:30 am–12:30 pm Structure-functional analysis of Stardust protein in Drosophila Ballroom of the Americas D-F eye. Natalia A. Bulgakova, Oezlem Kempkens, Elisabeth Knust. Institut of Genetics, Heinrich-Heine Universitaet, Pattern Formation I Duesseldorf, Germany. Moderator: Justin Kumar, Indiana University, 10:30 - Break Bloomington 108 - 11:00 100 - 8:30 Computational identification of regulatory elements in Gain of function screen identifies a factor promoting the Drosophila core promoters: Is there a “core promoter code”? 1 2 2 formation of an ectopic notum. Nicole Grieder, Walter Gehring. David Sturgill , Peter FitzGerald , Andrey Shyakhtenko , 1 2 Dept Cell Biology, Biozentrum, Basel, Switzerland. Brian Oliver , Charles Vinson . 1) LCDB, NIDDK/NIH, Bethesda, MD; 2) NCI/NIH, Bethesda, MD. 101 - 8:45 Matrix metalloproteinases: a role in imaginal disc 109 - 11:15 transdetermination. Anne Sustar1, Ansgar Klebes2,3, Tom Glorund, the elusive ovarian repressor of nanos translation. Kornberg2, Gerold Schubiger1. 1) Dept. Biology, Univ. Yossi Kalifa, Tao Huang, Lynne N. Rosen, Seema Chatterjee, Washington, Seattle, WA; 2) Inst. für Biologie-Genetik, Freie Elizabeth R. Gavis. Molecular Biology, Princeton University, Univ. Berlin, Germany; 3) Dept Biochemistry, UCSF, San Princeton, NJ. Francisco, CA. 110 - 11:30 102 - 9:00 Regulation of eye specification by the Six family of transcription A structure-function analysis of Fat and Dachsous in growth factors. Justin Kumar, Brandon Weasner, Claire Salzer. Dept control, proximo-distal patterning and planar cell polarity. Seth Biol, Indiana Univ, Bloomington, IN. S. Blair, Hitoshi Matakatsu. Dept Zoology, Univ Wisconsin, Madison, WI. 111 - 11:45 Gene-Specific Transcriptional Repression by Wnt Signaling. 103 - 9:15 Timothy Blauwkamp, Ming Fang, Mikyung Chang, Jinhee Additional sex combs affects antenna development via the Chang, Jiong Li, Ken Cadigan. MCDB Dept, University of regulation of Antp and Wg expression. Adi Salzberg1, Naomi Michigan, Ann Arbor, MI. Halachmi1, Karen Schulze2, Hugo Bellen2. 1) Department of Genetics, Rappaport Faculty of Medicine, Technion, Haifa 112 - 12:00 31096, Israel; 2) Department of Molecular and Human Coordination of cell fate specification and cell division by Genetics, Baylor College of Medicine, Houston, TX 77030. ubiquitin E3 ligase adaptor Phyllopod in sensory organ precursors. Hai-Wei Pi1, An-Chi Tien2, Pao-Ju Chang1, Hugo 2 104 - 9:30 Bellen . 1) Department of Life Science, Chang-Gung Identification of early cell survival cues during eye University, Kwei-Shan, Tao-Yuan 333, Taiwan; 2) Program in development in Drosophila. Amit Singh1, Kwang-Wook Choi1, Developmental Biology, Baylor College of Medicine, One 2, 3. 1) Molecular & Cellular Biology, Baylor College of Medicine, Baylor Plaza, Huston, TX 77730, USA. Houston, TX 77030, USA; 2) Program in Developmental Biology, Baylor College of Medicine, Houston, TX 77030, USA; 113 - 12:15 3) Department of Ophthalmology, Baylor College of Medicine, Clonal tumor induction due to progenitor cell transformation Houston, TX 77030, USA. in Drosophila. Frank Hirth, Heinrich Reichert, Bruno Bello. Biocenter/Pharmacenter, University of Basel, Switzerland. 105 - 9:45 Dpp signaling regulates patterning and epithelial integrity in the Drosophila retina. Julia B. Cordero, Ross L. Cagan. Dept Molec Biol & Pharmacology, Washington Univ, St Louis, St Louis, MO.

106 - 10:00 - Withdrawn

PLATFORM SESSIONS 35 Program number is in bold above the title. The first author is the presenter. Abstracts begin on page 79.

Saturday, April 1: 11:00 am–12:45 pm Saturday, April 1: 4:00 pm–6:00 pm Lanier Grand Ballroom A-B Ballroom of the Americas A-C

Immune System and Cell Death Regulation of Gene Expression Moderator: Andreas Bergmann, University of Texas, Moderator: Scott Barolo, University of Michigan Medical M. D. Anderson Cancer Center, Houston School, Ann Arbor

114 - 11:00 121 - 4:00 Hormonal regulation of innate immunity in D. melanogaster. Molecular basis of repressor recognition by Groucho. David Thomas Flatt1, Ermelinda Porpiglia2, Subba R. Palli3, Marc Ish-Horowicz1, Barbara H. Jennings1, S. Mark Wainwright1, Tatar1, Neal Silverman4. 1) Department of Ecology and Laura M. Pickles2, S. Mark Roe2, Laurence H. Pearl2. 1) Evolutionary Biology, Brown University, Providence, RI; 2) Developmental Genetics Laboratory, Cancer Research UK, University of Massachusetts Medical School, Worcester, MA; London, UK; 2) Section of Structural Biology, Institute of Cancer 3) Department of Entomology, Agricultural Science Center, Research, Chester Beatty Laboratories, London, UK. College of Agriculture, University of Kentucky, Lexington, KY; 4) Division of Infectious Disease, Department of Medicine, 122 - 4:15 University of Massachusetts Medical School, Worcester, MA. Squid, Cup, and polyA-binding protein cooperatively regulate gurken mRNA expression. K. Nicole Clouse, Trudi Schüpbach. 115 - 11:15 Howard Hughes Medical Institute, Department of Molecular Wound-induced inflammation in Drosophila larvae involves Biology, Princeton University, Princeton, NJ 08544. adhesive capture of hemocytes. Michael Galko1, Greg Fish2, Mark Krasnow2. 1) Dept. of Biochemistry and Molecular 123 - 4:30 Biology, MD Anderson Cancer Center, Houston, TX; 2) Medea sumoylation restricts the range of the Dpp signal. Wayne Department of Dept. of Biochemistry/HHMI, Stanford University, O. Miles1, Laurel A. Raftery2, Hilary L. Ashe1. 1) Faculty of Stanford, CA. Life Sciences, The University of Manchester, Manchester, United Kingdom; 2) Cutaneous Biology Research Center, 116 - 11:30 Massachusetts General Hospital and Harvard Medical School, The effector caspase drICE functions in developmental and Charlestown, MA. irradiation-induced cell death in Drosophila. Dongbin Xu, Yuan Wang, Regina Willecke, Zhihong Chen, Tian Ding, Andreas 124 - 4:45 Bergmann. Cancer Ctr, Houston, TX; 2) The Genes and Dynamics of Heat Shock Factor at Native Gene Loci Examined Development Graduate Program, Univ Texas MD Anderson by Multiphoton Imaging of Drosophila Polytene Nuclei in Living Cancer Ctr, Houston, TX. Tissue. Jie Yao1, Katherine Munson2, Watt W. Webb1, John T. Lis2. 1) Applied and Engineering Physics, Cornell University, 117 - 11:45 Ithaca, NY; 2) Molecular Biology and Genetics, Cornell Downregulation of diap1 confers competence for steroid- University, Ithaca, NY. triggered cell death. Arash Bashirullah, Voot Yin, Carl Thummel. HHMI, Department of Human Genetics, University 125 - 5:00 of Utah, Salt Lake City, UT. Genome Wide Mapping of The In Vivo DNA Binding Sites of Transcriptional Regulators of the Pregastrula Gene Network. 118 - 12:00 Xiao-Yong Li1, D. Nix1, S. MacArthur1, D. Pollard1, R. Characterization of Drosophila Morgue function revises current Bourghon2, V. Sementchenko3, T. R. Gingeras3, M. D. Biggin1, models of apoptosis regulation. Rebecca Hays. Biological M. B. Eisen1. 1) Berkeley Drosophila Transcription Network Sciences, Univ Kansas, Lawrence, KS. Project, Lawrence Berkeley National Lab, Berkeley, CA; 2) Statistics Department, UC Berkeley, CA; 3) Affymetrix, Inc., CA. 119 - 12:15 lola is required for proper chromatin structure and DNA 126 - 5:15 condensation during programmed cell death in oogenesis. B. Solving the signal-regulated enhancer: a structure-function Paige Bass, K. McCall. Biology Department, Boston approach. Scott Barolo. Dept. of Cell & Developmental Biology, University, Boston, MA. University of Michigan Medical School, Ann Arbor, MI.

120 - 12:30 127 - 5:30 Cytochrome-c-d regulates developmental apoptosis in the Polymerization of the Ets transcription factor Yan mediates Drosophila retina. César Mendes1, Eli Arama1, Samara chromatin spreading and repression in vivo. Pavithra Brown1, Heather Scherr2, Mayank Srivastava2, Andreas Vivekanand, Ilaria Rebay. Univ Chicago, Chicago, IL. Bergmann2, Hermann Steller1, Bertrand Mollereau1. 1) Howard Hughes Medical Institute, Strang Laboratory of Cancer 128 - 5:45 Research, The Rockefeller University, New York, NY; 2) The Non-cell autonomous tumor suppressor activity of the MVB University of Texas M.D. Anderson Cancer Center, Department sorting components Vps20, Vps28 and Snf7/Vps32. Thomas of Biochemistry and Molecular Biology, Houston, TX. Vaccari, David Bilder. Dept. of Molecular & Cell Biology University of California, Berkeley, Berkeley, CA. 36 PLATFORM SESSIONS Program number is in bold above the title. The first author is the presenter. Abstracts begin on page 79.

Saturday, April 1: 4:00 pm–6:00 pm 135 - 5:30 Ballroom of the Americas D-F Complex Interactions Between D/V and A/P Patterning Systems Before Gastrulation Revealed by a 3-D Atlas of Gene 1 Pattern Formation II Expression Patterns. Charless Fowlkes , Cris Luengo Hendriks2, Soile Keränen2, Angela DePace2, Gunther Moderator: Christine Rushlow, New York University, New Weber3, Oliver Rübel4, Min-Yu Huang3, Lisa Simirenko3, 3 2 2 Yo r k Bernd Hamann , Mike Eisen , Damir Sudar , David Knowles2, Mark Biggin2, Jitendra Malik1, Berkeley Drosophila Transcription Network Project. 1) Computer 129 - 4:00 Science Division, UC Berkeley, Berkeley, CA; 2) Life Sciences non-coding RNAs are integral components of the Dorsal- Division, LBNL, Berkeley, CA; 3) Institute for Data Analysis Ventral patterning network in Drosophila. Fred Biemar1, John and Visualization, UC Davis, Davis, CA; 4) Computer Science Manak2, Mike Levine1. 1) Dept Molecular & Cell Biol, Univ Department, University of Kaiserslautern, Germany. California, Berkeley, Berkeley, CA; 2) Affymetrix, Santa Clara, CA. 136 - 5:45 Drosophila Pipe protein function in the ovary and the 130 - 4:15 embryonic salivary gland. Xianjun Zhu1, Jonaki Sen2, Leslie The Drosophila microRNA iab-4-5p has homeotic activity and Stevens1, Jason Goltz1, David Stein1. 1) Section of Molecular directly represses Ultrabithorax. Eric Lai1, Matt Ronshaugen1, Cell & Developmental Biolohy and Institute for Cell and Joshua Hagen2, Mike Levine2. 1) Developmental Biology, Molecular Biology, The University Texas at Austin, Austin, TX, Sloan Kettering Institute, New York, NY; 2) Dept. of Molecular USA; 2) Department of Molecular Gentics, Albert Einstein and Cell Biology, UC Berkeley, Berkeley, CA. College of Medicine, Bronx, NY 10461, USA. 131 - 4:30 Echinoid mediates epithelial morphogenesis in the Drosophila ovary. Caroline Laplante, Laura A. Nilson. Dept Biol, McGill Univ, Montreal, PQ, Canada.

132 - 4:45 Crag, a gene regulating epithelial organization and morphogenesis. Natalie Denef1, 2, Yu Chen1, Trudi Schüpbach1, 2. 1) Molecular Biology, Princeton University, Princeton, NJ; 2) Howard Hughes Medical Institute.

133 - 5:00 Hedgehog maintains odd skipped cell lineage during Drosophila epidermis differentiation. Stephane Vincent, Jeff Axelrod. Dept Pathology, Stanford Univ Sch Med, Stanford, CA.

134 - 5:15 A 3D computational model for BMP dependent patterning of the Drosophila embryo based on positive feedback. David M. Umulis1, Mihaela Serpe2,3, Osamu Shimmi5, Wei-Shou Hu1, Hans Othmer4, Michael O’Connor2,3. 1) Chemical Engineering and Materials Science; 2) Genetics, Cell Biology and Development; 3) Howard Hughes Medical Institute; 4) School of Mathematics and Digital Technology Center, University of Minnesota, Minneapolis, MN; 5) Institute of Biotechnology, University of Helsinki, 00014 Helsinki, Finland.