The Skinny about Saturated Joel K. Kahn, MD, FACC @drjkahn Clinical Professor of Medicine Kahn Center for Cardiac Longevity Www.drjoelkahn.com

WTF? Or What The Health?

100 Years of Evidence Meet Ancel Keys, Ph.D., Ph.D. 1953: 6 Countries FAO Hypothesis Study 1957: Reanalysis of Later FAO Dataset

Keys Taught Low Sat Fat not Low Fat Keys: Scientist and Author

Classic Med Diet Pyramid in Pioppi How Do We Lose Our Path? #1: Gary Taubes, 2007 www.plantpositive.com The Media Loves the Big Fat Lie #2: Nina Teicholz, The Big Fat Surprise 2014 #3: Aseem Malhotra, MD, U.K. #4 Mark Hyman, MD: Eat Fat, Get Thin #5: Salim Yusuf, MD

Kahn 1, Yusuf 0 Kahn 1, Teicholz 0

Kahn 2, Yusuf/Teicholz 0 Malhotra, Redberg, Meier American College of Cardiology 2017

SnackHell’s Devil’s Food

The Holy Coconut Oil

PURE BS? PURE Funding

• The PURE Study is an investigator initiated study funded by the Population Health Research Institute, the Canadian Institutes of Health Research (CIHR), Heart and Stroke Foundation of Ontario, support from CIHR’s Strategy for Patient Oriented Research (SPOR) through the Ontario SPOR Support Unit, as well as the Ontario Ministry of Health and LongTerm Care and through unrestricted grants from several pharmaceutical companies, with major contributions from AstraZeneca (Canada), SanofiAventis (France and Canada), Boehringer Ingelheim (Germany and Canada), Servier, and GlaxoSmithkline, and additional contributions from Novartis and King Pharma and from various national or local organisations in participating countries Kahn 3, Teicholz 0 David Katz, MD Comments

• “very poor people with barely anything to eat get sick and die more often than affluent people with access to both ample diets, and hospitals.” One certainly understands why the media did NOT choose that! It is, however, true- and entirely consistent with the data” Marion Nestle (Food Politics) Comments

•This study confirms that the single most important risk factor for poor health is poverty. The study results are consistent with the idea that largely plant-based diets are good for health. James Hamblin, The Atlantic, comments

•The practically important findings were that the healthiest people in the world had diets that are full of fruits, beans, seeds, vegetables, and whole grains, and low in refined and . 5 Deceptions to Confuse the Public

• Sugar is the Problem Now so Saturated Fat is not • Butter is Back • Full-fat Dairy is Better • Low-fat Diets Fail • Saturated Fat is Not the Cause of Heart Disease Sugar is the Problem Now so Saturated Fat is not

Butter is Back

Full-Fat Dairy is Better Low-fat Diets Fail Sat Fat is Not the Cause of Heart Disease The War Over Saturated Fat: Not Hypothetical Harvard School of Public Health

Effect of FMD on Patients

Wei et al., Sci. Transl. Med. 9, 15 February 2017 Effects of FMD on Elevated Risk Cohorts

Wei et al., Sci. Transl. Med. 9, 15 February 2017 Fasting Mimicking Diet Circulating Stem Cells in Humans Undergoing FMD Cycles

1.2

0.8

0.4

0 Normal Diet FMD

Brandhorst S, Choi I, et al. Cell Metabolism, 2015. Science is Far From Perfect But The Truth Will Emerge Over Time