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Rabbit Anti-RAB11FIP1 antibody

SL21126R

Product Name: RAB11FIP1 Chinese Name: G蛋白Binding proteinRAB相互作用蛋白抗体 FLJ22524; FLJ22622; HGNC:30265; MGC78448; No Rab11 binding 1A; NOEL1A; Rab coupling protein; Rab effector protein; Rab interacting recycling Alias: protein; Rab-coupling protein; RAB11 family interacting protein 1 (class I); Rab11 family interacting protein 1D; Rab11 family-interacting protein 1; Rab11 FIP1; Rab11- FIP1; RCP; RFIP1_HUMAN. Organism Species: Rabbit Clonality: Polyclonal React Species: Human, ELISA=1:500-1000IHC-P=1:400-800IHC-F=1:400-800ICC=1:100-500IF=1:100- 500（Paraffin sections need antigen repair） Applications: not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. Molecular weight: 137kDa Cellular localization: cytoplasmic Form: Lyophilized or Liquid Concentration: 1mg/mlwww.sunlongbiotech.com immunogen: KLH conjugated synthetic peptide derived from human RAB11FIP1:1101-1200/1283 Lsotype: IgG Purification: affinity purified by Protein A Storage Buffer: Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year Storage: when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. PubMed: PubMed This encodes one of the Rab11-family interacting (Rab11-FIPs), which Product Detail: play a role in the Rab-11 mediated recycling of vesicles. The encoded protein may be involved in endocytic sorting, trafficking of proteins including integrin subunits and epidermal growth factor receptor (EGFR), and transport between the recycling endosome and the trans-Golgi network. Alternative splicing results in multiple transcript variants. A pseudogene is described on the X . [provided by RefSeq, Dec 2013]

Function: A Rab11 effector protein involved in the endosomal recycling process. Also involved in controlling membrane trafficking along the phagocytic pathway and in phagocytosis.

Subcellular Location: Recycling endosome. Rab11A rather than Rab4A mediates localization in the endocytic recycling compartment (ERC) and Cytoplasmic vesicle, phagosome membrane. Membrane-bound (isoform 2). Colocalizes with Rab11A at phagosomes (isoform 2).

Tissue Specificity: Isoform 2 is expressed in brain, heart, testis, lung, spleen, ovary and small intestine.

Similarity: Contains 1 C2 domain. Contains 1 FIP-RBD domain.

SWISS: Q6WKZ4

Gene ID: 80223

Database links:

Entrez Gene: 80223 Human

Entrez Gene: 75767 Mouse Entrezwww.sunlongbiotech.com Gene: 498650 Rat Omim: 608737 Human

SwissProt: Q6WKZ4 Human

SwissProt: Q9D620 Mouse

SwissProt: Q3B7T9 Rat

Unigene: 191179 Human

Unigene: 205335 Mouse Unigene: 49288 Rat

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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