Curriculum Vitae
RAVINDRANATH DUGGIRALA
PERSONAL INFORMATION:
HOME ADDRESS: 3200 Trailblazer Ave. Edinburg, TX 78541
9314 Aspen Oak San Antonio, TX 78254
Home Phone: 956-287-4691 (Edinburg) 210-520-9497 (San Antonio)
BUSINESS ADDRESS: Department of Human Genetics and South Texas Diabetes and Obesity Institute Edinburg Research Education Building (E-REBL) School of Medicine University of Texas Rio Grande Valley 1214 W. Schunior St. Edinburg, Texas 78541
Office Phone: 956-665-6456 (office) 210-326-0806 (cell)
Office Fax: 956-665-6402
E-mail Address: [email protected]
RESEARCH INTERESTS:
Genetic Epidemiology Statistical Genetics Anthropological Genetics Type 2 Diabetes Obesity Childhood Obesity Metabolic Syndrome Gallbladder Disease Birth Weight and Adult Diseases Tuberculosis Children Health Minority Health
EDUCATION:
1972-1975 B.Sc. (Zoology, Botany, and Chemistry), Andhra Christian College, Guntur, A.P., India, 1976.
1 1976-1978 M.Sc. (Human Genetics and Physical Anthropology), Andhra University, Visakhapatnam, A.P., India, 1978.
1986-1988 M.A. (Anthropology), University of Montana, Missoula, MT, 1991.
1989-1995 Ph.D. (Anthropology), University of Kansas, Lawrence, KS. Major Field: Biological Anthropology (Population Genetics and Quantitative Genetics), 1995.
Ph.D. Dissertation Title: Cultural and genetic determinants of lipids and lipoproteins in the Mennonite Community, University of Kansas, Lawrence, KS, 1995. (Advisor: Dr. Michael H. Crawford, Ph.D.)
Postdoctoral Research Fellow: Genetic epidemiology of complex diseases, with an emphasis on type 2 diabetes and its related disease conditions in Mexican Americans, Division of Clinical Epidemiology, Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, 1995-1997. (Mentor: Dr. Michael P. Stern, M.D.).
EXPERIENCE:
Research:
1982-1985 Research Fellow, University Grants Commission (India), Dept. of Anthropology, Andhra University, Visakhapatnam, India.
1988-1988 Research Assistant. Archaeological Records Office, Dept. of Anthropology, Univ. of Montana, Missoula, MT (Fall, 1988).
1991-1994 Research Assistant. Dept. of Anthropology, Univ. of Kansas, Lawrence, KS (Summer and Fall, 1991; Spring, 1992; and Fall, 1994).
1992-1992 Research Assistant, Dept. of Anthropology, State University of New York College at Oneonta, Oneonta, NY (Summer, 1992).
1995*-1996 American Diabetes Association Mentor-based Post-doctoral Fellow, Division of Clinical Epidemiology, Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX. *Started in December 1994.
1996-1997 Research Fellow, Division of Clinical Epidemiology, Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX.
1995-1997 Postdoctoral Scientist (Adjunct), Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX.
1997-2002 Assistant Professor (Research), Division of Clinical Epidemiology, Department of Medicine, University of Texas Health Science Center at San Antonio, TX.
1997-2002 Assistant Scientist (Adjunct), Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX.
2 2002-2007 Associate Scientist, Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX.
2002-2007 Adjunct Associate Professor (Research), Division of Clinical Epidemiology, Department of Medicine, University of Texas Health Science Center at San Antonio, TX.
2006-2011 Allied Health Professional, University Health System, San Antonio, TX.
2007-2015 Scientist, Department of Genetics, Texas Biomedical Research Institute, San Antonio, TX.
2007-2015 Adjunct Professor (Research), Divisions of Clinical Epidemiology and Diabetes, Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX.
2015* Professor, South Texas Diabetes and Obesity Institute, Edinburg Regional Academic Health Center, University of Texas Health Science Center at San Antonio, Edinburgh, TX. *January-August 2015.
2015- Professor, South Texas Diabetes and Obesity Institute, Edinburg Research Education Building, School of Medicine, University of Texas Rio Grande Valley (UTRGV), Edinburg, TX.
2017- Professor, Department of Human Genetics, School of Medicine, UTRGV, Edinburg, TX.
2017- Adjunct Professor, Division of Diabetes, Department of Medicine, University of Texas Health San Antonio (UTHSA), San Antonio, TX.
2018- McAllen Medical Center Foundation Endowed Professor in Diabetes Research, School of Medicine, UTRGV, Edinburg, TX.
Teaching:
1975-1976 Teacher and Assistant Principal, Tagore Tutorial College, Emanipalem, Ongole, AP, India.
1985-1986 Museum Keeper (with teaching assignments), Dept. of Anthropology, Andhra University, Visakhapatnam, India.
1990-1990 Teaching Assistant, Introduction to cultural anthropology (ANTH 108/308), Dept. of Anthropology, University of Kansas, Lawrence, KS (Spring, 1990).
1991-1991 Teaching Assistant, Introduction to physical anthropology (ANTH 104/304), Dept. of Anthropology, University of Kansas, Lawrence, KS (Spring, 1991).
1992-1993 Instructor (GTA), Human variation and evolution (ANTH 340), Dept. of Anthropology, University of Kansas, Lawrence, KS (Fall, 1992 and Spring, 1993).
3 1993-1994 Instructor (GTA), Controversies on the living and the dead (ANTH 352), Dept. of Anthropology, University of Kansas, Lawrence, KS (Fall, 1993 and Spring, 1994).
Student, postdoctoral fellow, junior faculty, and visiting research scientist mentoring and/or scientific interactions:
Mentor for Ms. Cindy Peńa, a student at the Health Professions High School at Edison, San Antonio, TX, who did research on genetics of type 2 diabetes for a presentation on May 16th, 2000, under the supervision of Mrs. Krog at Edison.
Mentor for Ms. Preethi Durgam, a student at the Health Careers High School, San Antonio, TX, who did preliminary research on diabetes and related phenotypes in Mexican Americans and non-Hispanic Europeans, 2000.
Together with Dr. Michael P. Stern, mentored post-doctoral fellows Drs. Rector Arya, Kelly Hunt, and Donna Lehman in the area of genetic epidemiology, Division of Clinical Epidemiology, Dept. of Medicine, University of Texas Health Science Center at San Antonio, TX.
Mentor for Dr. Sobha Puppala (Staff Scientist) in the area of genetic epidemiology, Department of Genetics, Texas Biomedical Research Institute, San Antonio, 2003-2015.
Dissertation Committee Member for Ms. Guowen Cai, a Ph.D. student in the Department of Nutrition at the University of Texas at Austin, 2004.
Mentor for Dr. Vidya Farook (Staff Scientist) in the area of genetic epidemiology, Department of Genetics, Texas Biomedical Research Institute, San Antonio, 2004-2015.
Provided short-term training in genetic epidemiological techniques for Dr. Samudrala Narahari, a Visiting Professor from the Department of Anthropology, Andhra University, Visakhapatnam, Andhra Pradesh, India, 2007.
Graduate Faculty Status (Ad Hoc) for Ms. Geetha Chittoor’s comprehensive/final oral exam doctoral committee, Department of Anthropology, University of Kansas, Lawrence, KS, 2007- 2010.
Together with Dr. Michael H. Crawford, Department of Anthropology, University of Kansas, Lawrence, KS, mentored Dr. Alvaro Diaz-Badillo, a visiting postdoctoral research scholar from CINVESTAV of the National Polytechnic Institute, Mexico City, Mexico, funded by CONACYT of the Federal Government of Mexico, Mexico, 2009-2010.
Mentor for Dr. Geetha Chittoor, a Cowles Postdoctoral Fellow at the Texas Biomedical Research Institute, San Antonio, TX, 2010-2012.
Mentor for Dr. Geetha Chittoor, Postdoctoral Scientist, Department of Genetics, Texas Biomedical Research Institute, San Antonio, TX, 2012-2014.
Interacted with Dr. Solomon F. D. Paul, a Visiting Professor and Head of the Department of Human Genetics, Sri Ramachandra University, Chennai, Tamil Nadu, India regarding training in advanced genetic epidemiologic analytical techniques and their applications to common
4 complex diseases. 2012-2013.
Supervisor for Mr. Miguel Aguilar, Student Intern, Department of Genetics, Texas Biomedical Research Institute, San Antonio, TX, 2013-2014.
Supervisor for Ms. Azaneth Arellanes, Student Intern, Department of Genetics, Texas Biomedical Research Institute, San Antonio, TX, 2013-2015.
Supervisor for Mr. Pratik Patel, Student Intern, Department of Genetics, Texas Biomedical Research Institute, San Antonio, TX, 2014-2015.
Mentor for Mr. Sunil Athyala, High School Student Intern (Tom C. Clark High School, San Antonio, TX), South Texas Diabetes and Obesity Institute (STDOI) Annex, University of Texas Rio Grande Valley (UTRGV), TX, 2015 (Summer).
Overall Supervision for Ms. Naba Asif (together with Drs. Christopher P. Jenkinson, Srinivas Mummidi, Rector Arya, Juan Carlos Lopez-Alvarenga and Ms. Liza Morales Smith), Volunteer Student Research Assistant, STDOI, Edinburg, TX, 2016-2017.
Mentor for Mr. Armando Totomoch Serra (together with Dr. Lopez-Alvarenga), Ph.D. Student, Laboratorio 1 del Departamento de Genética y Biología Molecular del Centro de Investigación y estudios Avanzados del Instituto Politécnico Nacional Av. Instituto Politécnico Nacional 2508, Col. San Pedro Zacatenco, Delegación Gustavo A. Madero, México D.F., Mexico, CONACYT Fellowship, September-November, 2016.
Mentor for Dr. Alvaro Diaz-Badillo (Assistant Research Scientist) in the in the areas of genetic epidemiology and statistical genetics, South Texas Diabetes and Obesity Institute (STDOI), School of Medicine, UTRGV, Edinburg,TX, 2016-2018.
Mentor for Ms. Melissa Ku (together with Dr. Juan Carlos Lopez-Alvarenga), Undergraduate Student (Nursing), Course 4000.26 – Directed Research, Department of Human Genetics and STDOI, School of Medicine, UTRGV, Edinburg, TX, Spring 2018.
Field work:
1977 Collection of anthropometric data from the Koya tribal group of Andhra Pradesh, Andhra University, Waltair, AP, India.
1989-1990 Collection of dermatoglyphic data for the Midwest Twin Registry, Laboratory of Biological Anthropology, University of Kansas, Lawrence, KS.
1998- Has been directing Mexican American Family Studies (initiation and/or follow-up) in San Antonio, TX, including supervision of recruitment- and data collection- related activities.
Administrative:
1975-1976 Assistant Principal, Tagore Tutorial College, Emanipalem, Ongole, AP, India.
5 1978-1982 Cashier, Indian Bank, Maharanipet, Visakhapatnam, AP, India.
1984-1985 Secretary, Andhra University Research Scholars' Association, Waltair, AP, India.
1985-1986 Deputy Warden for Arts, Commerce and Law Colleges' Hostels, Waltair, AP, India.
2007-2008 Vice President, American Association of Anthropological Genetics.
2008-2009 President, American Association of Anthropological Genetics.
2009-2010 Executive Committee Member, American Association of Anthropological Genetics.
HONORS AND AWARDS:
1972 Certificate of Merit, Literary Association, ABM Junior College, Ongole, A.P., India, Second prize, total marks contest: Intermediate Class 1970-72.
1972 Certificate of Merit, Literary Association, ABM Junior College, Ongole, A.P., India, First prize, total marks contest in biological sciences, 1970-72.
1982-1985 University Grants Commission (India) Research Fellowship, Department of Anthropology, Andhra University, Visakhapatnam, A.P., India.
1987 Ludwig G. Broman Fellowship in Museum studies, Fort Missoula Museum, Missoula, MT.
1986-1990 Government of India National Overseas Scholarship.
1990 Graduate Research Paper Presenter Fund Award to attend the annual meeting of the American Association of Physical Anthropologists, Miami, 1990, Department of Anthropology, University of Kansas, Lawrence, KS.
1994 Carroll Clark Award to present a poster at the annual meeting of the American Association of Physical Anthropologists, Denver, 1994, Department of Anthropology, University of Kansas, Lawrence, KS.
1994 Honors in Ph.D. Comprehensive Examination, Department of Anthropology, University of Kansas, Lawrence, KS, 1994.
1994-1996 Mentor-based Post-doctoral Fellowship awarded by the American Diabetes Association, Division of Clinical Epidemiology, Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX (Mentor: Dr. Michael P. Stern M.D.).
1995 Finalist (1 of 5) for the North American Association for the Study of Obesity (NAASO) Young Investigator Award. NAASO-SSIB Annual Meeting, October 12- 17, 1995. Baton Rouge, LA.
6 2004 Marquis Who's Who in America, 2004.
2010 Hind Rattan Award (2010), Received from the Non-Resident Indians Welfare Society of India, which makes about 30 awards each year to the Indian Diaspora – nonresident natives of India or people of Indian descent – who make significant contributions in their respective fields. The awards were presented at the Society’s International Congress in New Delhi, India on Jan. 25, 2010, the eve of India’s 61th Republic Day.
2014 Top Ranked U.S. Executives, National Council of American Executives - 2014.
2017 Recognition at the 2016 UTRGV Faculty Excellence Awards and Recognition Ceremony/Luncheon for generating major grant funding.
2018- McAllen Medical Center Foundation Endowed Professor in Diabetes Research, School of Medicine, UTRGV, Edinburg, TX.
PROFESSIONAL MEMBERSHIPS:
Member, American Diabetes Association Member, American Society of Human Genetics Member, Obesity society Member, American Association of Anthropological Geneticists
PROFESSIONAL ACTIVITIES:
Reviewed manuscripts for the following journals:
American Journal of Human Genetics American Journal of Human Biology American Journal of Gastroenterology Annals of Human Genetics Archives of Internal Medicine Archives of Medical Research Arthritis Care and Research BMC Medical Genetics Clinical Journal of the American Society of Nephrology Diabetes Diabetes/Metabolism Research and Reviews Diabetic Medicine Diabetologia Diabetology & Metabolic Syndrome Diabetes and Vascular Disease Research European Journal of Human Genetics Genetic Analysis Workshop 13 Contributions/Biomedical Central Supplement Genetic Analysis Workshop 15 Proceedings Genetic Epidemiology Human Genetics Human Heredity
7 Human Biology JAMA Network Open Journal of the American Medical Association (JAMA) Journal of Clinical Endocrinology & Metabolism Journal of Clinical Investigation Journal of Diabetes and Its Complications Journal of Gerontology: Biological Sciences Journal of Pediatrics Kidney International Mechanisms of Ageing and Development Molecular Nutrition and Food Research Nature Communications Nature Genetics Nutrition, Metabolism, and Cardiovascular Diseases Obesity Research or Obesity PLoS One Translational Research
1997-2004 Member, the International Type 2 Diabetes Linkage Analysis Consortium, Served as the contact person for the University of Texas Health Science Center at San Antonio (UTHSCSA) research group, San Antonio, TX.
2000 Chair, Local Arrangements, 25th Human Biology Association Annual Meeting, April 10-12, 2000, San Antonio, TX.
2000-2005 Member, Analysis and Mapping Committee, the International Type 2 Diabetes Linkage Analysis Consortium.
2002 Reviewer, SCOR application, National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, 2002.
2002-2015 Alternate Member, Institutional Review Board (IRB-1), UTHSCSA, San Antonio, TX
2003 CME Faculty, International Congress on Nutrition and Obesity, Monterrey, Mexico, July 4-7, 2003.
2004 Convener, Scientific Organizing Committee (US), Indo-US Workshop on “Genetics of Complex Diseases with an Emphasis on Type 2 Diabetes” held in Vizag, Andhra Pradesh, India, March 30 – April1 2004.
2004 Ad Hoc Reviewer, American Diabetes Association Grant Review Panel.
2004 Session Chair for “Genetics of Obesity and Insulin Resistance” at the ADA's 64th Scientific Sessions, Orlando, FL, June 4-8, 2004.
2004-2007 Chair, Elections and nominations committee, the American Association of Anthropological Geneticists.
8 2004-2008 Member, American Diabetes Association Grant Review Panel (GRP).
2005 Member, Forum Grant Review Committee: Review of 2005 Internal Grant Applications, Southwest Foundation for Biomedical Research, San Antonio, TX.
2006 Member, State of Pennsylvania Department of Health Obesity Research Merit Review Panel.
2006 Abstract Reviewer for American Diabetes Association’s 66th Scientific Sessions, Washington, DC, June 9-13, 2006.
2006 Session Chair for “Childhood Obesity - From Epidemiology to Treatment” at the ADA’s 66th Scientifc Sessions, Washington, DC, June 9-13, 2006.
2006-2007 Grant Application Reviewer, The Deutsche Forschungsgemeinschaft (German Research Foundation).
2007 Reviewer, Pennsylvania Department of Health (PA DOH) Performance Review.
2007 Coordinator (USA), Diversity to Discovery: A training course in Genetic Epidemiology and Molecular Genetics, Anthropological Survey of India, Mysore, Karnataka, India, March 31-April 22, 2007.
2007 Session Chair for “Gene-Environment Interactions and Metabolism in Obesity and Type 2 Diabetes” at the ADA’s 67th Scientifc Sessions, Chicago, IL, June 22- 26, 2007.
2007 Member, Voelcker Foundation Application Review Committee: Review of Voelcker Pilot Study Grant Applications, Southwest Foundation for Biomedical Research, San Antonio, TX.
2007- U.S. Consortium Steering Committee Member, International Consortium for the Study of Tuberculosis (ICST), University of Kansas, Lawrence, KS.
2007-2015 Member, Analysis Committee, Family Investigation of Nephropathy and Diabetes (FIND).
2007-2008 Vice President (elected), American Association of Anthropological Genetics.
2007-2015 Member, Institutional Review Board (IRB-3), University of Texas Health Science Center, San Antonio, TX.
2007-2013 Member, External Advisory Committee, Center for Biologic Research Excellence (CoBRE), Division of Endocrinology and Diabetes, Department of Medicine, University of Oklahoma Health Science Center, Oklahoma City, OK.
2007-2015 Member, Faculty Promotions Committee, Department of Genetics, Southwest Foundation for Biomedical Research (later called, Texas Biomedical Research Institute), San Antonio, TX.
9 2007-2015 Member, Technical Staff Promotions Committee, Department of Genetics, Southwest Foundation for Biomedical Research (later called, Texas Biomedical Research Institute), San Antonio, TX.
2008 Reviewer, Pennsylvania Department of Health (PA DOH) Performance Review.
2008 Coordinator (USA), Diversity to Discovery: A training course in Genetic Epidemiology and Molecular Genetics, Anthropological Survey of India, Mysore, Karnataka, India, March 15-28, 2008.
2008 Member, National and International Advisory Committee, 33rd Annual Conference of the Indian Society of Human Genetics and International Symposium on Genetics Revisited: the Genomics and Proteomics Advantage, Andhra University, Visakhapatnam, A.P., India, February 11-13, 2008.
2008 Session Chair, 33rd Annual Conference of the Indian Society of Human Genetics and International Symposium on Genetics Revisited: the Genomics and Proteomics Advantage, Andhra University, Visakhapatnam, A.P., India, February 11-13, 2008.
2008 Coordinator, Symposium sponsored by the American Association of Anthropological Geneticists: “Human and Non-Human Primate Genetics in the Post-Genomic Era”, held at the 77th annual meeting of the American Association of Physical Anthropologists, Columbus, Ohio, April 7-13, 2008.
2008 CME Faculty/Speaker, Genetics of Diabetes in Mexican Americans, Texas Diabetes Institute, San Antonio, TX, September 27, 2008.
2008 Reviewer, Special Emphasis Panel, Epidemiology of Chronic and Acute Outcomes, NIH.
2008 Ad Hoc Reviewer, Neurological, Aging and Musculoskeletal Epidemiology (NAME) Study Section, NIH.
2008-2009 President (elected), American Association of Anthropological Genetics.
2008-2012 Advisory Member (Abroad), Genome India International (GII).
2009 Coordinator (USA), Diversity to Discovery: A training course in Genetic Epidemiology and Molecular Genetics, Anthropological Survey of India, Mysore, Karnataka, India, March 12–24, 2009.
2009 Ad Hoc Reviewer, Neurological, Aging and Musculoskeletal Epidemiology (NAME) Study Section, NIH.
2009 Reviewer, Institute for Integration of Medicine and Science (IIMS)/Clinical and Translational Science Award (CTSA), Pilot Projects, University of Texas Health Science Center at San Antonio, San Antonio, TX, 2009.
10 2009 Reviewer, Indo-US Science & Technology Forum (IUSSTF) Grants.
2009 Ad Hoc Reviewer, Genetics of Health and Disease (GHD) Study Section, ZRG1 GGG-C (95) S, and ZRG1 PSE-B (04), NIH.
2009-2010 Executive Committee Member, American Association of Anthropological Genetics.
2009-2015 Alternate Member, Institutional Review Board (IRB-2), University of Texas Health Science Center, San Antonio, TX.
2009- Member, Steering Committee, Type 2 Diabetes (T2D) Genetic Exploration by Next-generation sequencing in Ethnic Samples (T2D-GENES) Consortium (NIDDK).
2010 Member, Review Panel (Mail), ZRG1 HDM-K (55) ROD-10-005, NIH.
2010 Member, Review-Member Conflict Panel, PSE IRG, ZRG1 PSE-04M, NIH.
2010 Member, Voelcker Grant Review Panel, Southwest Foundation for Biomedical Research, San Antonio, TX.
2010 Member, Forum Grant Review Panel, Southwest Foundation for Biomedical Research, San Antonio, TX.
2010-2014 Regular Member, Neurological, Aging and Musculoskeletal Epidemiology (NAME) Study Section, NIH.
2011 Abstract Reviewer for American Diabetes Association’s 71st Scientific Sessions, San Diego, CA, June 24-28, 2011.
2011 Grant Application Reviewer, The Deutsche Forschungsgemeinschaft (German Research Foundation).
2011-2013 Member, Publications and Data Access Committee, T2D-GENES Consortium.
2011 Review Editor, Frontiers in Applied Genetic Epidemiology Journal.
2012 Reviewer, Institute for Integration of Medicine and Science (IIMS)/Clinical and Translational Science Award (CTSA), Pilot Projects, University of Texas Health Science Center at San Antonio, San Antonio, TX, 2012.
2013 Member, Forum Grant Review Panel, Texas Biomedical Research Institute, San Antonio, TX.
2014-2015 Alternate Member, Institutional Review Board (IRB-E), University of Texas Health Science Center, San Antonio, TX.
2015- Member, Steering Committee, Accelerating Medicines Partnership (AMP) T2D-
11 GENES Consortium (NIDDK).
2015 Member, Veterans Affairs (VA) SPLM (MVP beta-test projects) Review Committee (Teleconference Participant).
2015-2018 Member, University of Rio Grande Valley (UTHRGV) School of Medicine (SOM) Admissions Committee.
2015-2016 Member, Institutional Review Board (IRB), UTRGV, Valley, Edinburg, TX.
2015 Reviewer, Institute for Integration of Medicine and Science (IIMS)/Clinical and Translational Science Award (CTSA), Pilot Projects, University of Texas Health Science Center at San Antonio, San Antonio, TX, 2015.
2016 Reviewer, American Diabetes Association (ADA) 76th Scientific Session’s Abstracts.
2016- Co-Chair, Steering Committee, INDIGENIUS (Indian Diabetes Genetic Studies in collaboration with US) Consortium.
2016 Member, Special Emphasis Panel, ZRG1 PSE-P 02 M, NIH.
2016-2019 Alternate Member, Institutional Review Board, UTHSA, San Antonio, TX.
2017 Member, Special Emphasis Panel, ZRG1 GGG-D (90) Gabriella Miller Kids First Pediatric Research Program and GGG members conflicts, NIH.
2018 Member, School of Medicine (UTRGV) Strategic Planning Work Group (Education).
2018 Member, School of Medicine (UTRGV) Research Symposium Planning Committee.
2018 Reviewer, School of Medicine (UTRGV) Research Symposium Abstracts.
2018 Member, NIAMS Ancillary Studies Review Committee (ZAR1 YL (M1)), NIH.
2018- Member, Department of Human Genetics, SOM, UTRGV, Faculty Evaluation and Promotion Committee.
2019- Member, UPIRSO-Noncompliance (UP/NC) Subcommittee, IRB, University of Texas Health San Antonio (UTHSA), San Antonio, TX.
2019 Reviewer, ConTex Collaborative Research Grants Competition, University of Texas at San Antonio, San Antonio, TX.
2020 Reviewer (Mail), Transformative Research Award (TRA) Initiative Review Committee, Special Emphasis Panel, ZRG1 BCMB - A51, NIH, 2020.
12 PUBLICATIONS:
A.) Articles:
1. Duggirala R, Injeti MS, Busi BR (1984) Anthropometric variation among Koyas. Hum Hered. 34(2):131-132. PMID: 6745953.
2. Duggirala R, Rao BD, Busi BR (1984) Dental morphology among the inmates of Andhra University, Visakhapatnam. In V. R. Reddy (ed) Dental Anthropology: Applications and methods. New Delhi: Inter-India Publications, pp. 161-164.
3. Rao BD, Duggirala R, Busi BR (1984) Dental pathology and morphology among the Yadavas and Pallis of Srikakulam district, Andhra Pradesh. In V. R. Reddy (ed) Dental Anthropology: Applications and methods. New Delhi: Inter-India Publications, pp. 117- 128.
4. B. R. Busi, Duggirala R, Rao BD (1984) Dental caries among the students of Andhra University, Visakhapatnam. In V. R. Reddy (ed) Dental Anthropology: Applications and methods. New Delhi: Inter-India Publications, pp. 111-115.
5. Duggirala R, Crawford MH, and Koertvelyessy T (1991) Mating structure of Tarpa, Northeastern Hungary: 1780-1979, based on isonymy and repeated pairs (RP) methods. J Indian Anthropol Soc. 26:63-75.
6. Crawford MH, Duggirala R (1992) Digital dermatoglyphic patterns of Eskimo and merindian populations: relationships between geographic, dermatoglyphic, genetic, and linguistic distances. Hum Biol. 64(5):683-704. PMID: 1398610.
7. Novoradovsky AG, Spitsyn VA, Duggirala R, Crawford MH (1993) Population genetics and structure of Buryats from the Lake Baikal Region of Siberia. Hum Biol. 65(5):689- 710. PMID: 8262501.
8. Sirajuddin SM, Duggirala R, Crawford MH (1994) Population structure of the Chenchu and other south Indian tribal groups: relationships between genetic, anthropometric, dermatoglyphic, geographic, and linguistic distances. Hum Biol. 66(5):865-84. PMID: 8001914.
9. Comuzzie AG, Duggirala R, Leonard WR, Crawford MH (1995) Population relationships among historical and modern indigenous Siberians based on anthropometric characters. Hum Biol. 67(3):459-79. PMID: 7607637.
10. Crawford MH, Koertevlyessy T, Huntsman RG, Collins M, Duggirala R, Martin L, and Keeping D (1995) Effects of religion, economics, and geography on genetic structure of Fogo Island, Newfoundland. Am J Hum Biol 7:437-451.
11. Duggirala R, González Villalpando C, O'Leary DH, Stern MP, Blangero J (1996) Genetic basis of variation in carotid artery wall thickness. Stroke. 27(5):833-7. PMID: 8623101.
12. Stern MP, Duggirala R, Mitchell BD, Reinhart LJ, Shivakumar S, Shipman PA, Uresandi
13 OC, Benavides E, Blangero J, O'Connell P (1996) Evidence for linkage of regions on chromosomes 6 and 11 to plasma glucose concentrations in Mexican Americans. Genome Res. 6(8):724-34. PMID: 8858347.
13. Duggirala R, Stern MP, Mitchell BD, Reinhart LJ, Shipman PA, Uresandi OC, Chung WK, Leibel RL, Hales CN, O'Connell P, Blangero J (1996) Quantitative variation in obesity-related traits and insulin precursors linked to the OB gene region on human chromosome 7. Am J Hum Genet. 59(3):694-703. PMID: 8751871; PMCID: PMC1914918.
14. Duggirala R, Williams JT, Williams-Blangero S, Blangero J (1997) A variance component approach to dichotomous trait linkage analysis using a threshold model. Genet Epidemiol. 14(6):987-92. PubMed PMID: 9433612.
15. Williams JT, Duggirala R, Blangero J (1997) Statistical properties of a variance components method for quantitative trait linkage analysis in nuclear families and extended pedigrees. Genet Epidemiol. 1997;14(6):1065-70. PMID: 9433625.
16. Crawford MH, Williams JT, Duggirala R (1997) Genetic structure of the indigenous populations of Siberia. Am J Phys Anthropol. 104(2):177-92. PMID: 9386825.
17. Goksel DL, Fischbach K, Duggirala R, Mitchell BD, Aguilar-Bryan L, Blangero J, Stern MP, O'Connell P (1998) Variant in sulfonylurea receptor-1 gene is associated with high insulin concentrations in non-diabetic Mexican Americans: SUR-1 gene variant and hyperinsulinemia. Hum Genet. 103(3):280-5. PMID: 9799081.
18. Duggirala R, Mitchell BD, Blangero J, Stern MP (1999) Genetic determinants of variation in gallbladder disease in the Mexican-American population. Genet Epidemiol. 16(2):191-204. PubMed PMID: 10030401.
19. Duggirala R, Almasy L, Blangero J (1999) Smoking behavior is under the influence of a major quantitative trait locus on human chromosome 5q. Genet Epidemiol. 17 Suppl 1:S139-44. PubMed PMID: 10597426.
20. Duggirala R, Blangero J, Almasy L, Dyer TD, Williams KL, Leach RJ, O'Connell P, Stern MP (1999) Linkage of type 2 diabetes mellitus and of age at onset to a genetic location on chromosome 10q in Mexican Americans. Am J Hum Genet. 64(4):1127-40. PMID: 10090898; PMCID: PMC1377837.
21. Crawford MH, Koertvelyessy T, Pap M, Szilagyi KK, Duggirala R (1999) The effects of a new political border on the migration patterns and predicted kinship (PHI) in a subdivided Hungarian agricultural population: Tiszahat. HOMO 50:201-210.
22. Wooten EC, Fults D, Duggirala R, Williams K, Kyritsis AP, Bondy ML, Levin VA, O'Connell P (1999) A study of loss of heterozygosity at 70 loci in anaplastic astrocytoma and glioblastoma multiforme with implications for tumor evolution. Neuro Oncol. 1(3):169-76. PMID: 11550311; PMCID: PMC1920743.
23. Stern MP, Bartley M, Duggirala R, Bradshaw B (2000) Birth weight and the metabolic
14 syndrome: thrifty phenotype or thrifty genotype? Diabetes Metab Res Rev. 16(2):88-93. PMID: 10751748.
24. Duggirala R, Blangero J, Almasy L, Dyer TD, Williams KL, Leach RJ, O'Connell P, Stern MP (2000) A major susceptibility locus influencing plasma triglyceride concentrations is located on chromosome 15q in Mexican Americans. Am J Hum Genet. 66(4):1237-45. Epub 2000 Mar 21. PMID: 10729112; PMCID: PMC1288191.
25. Burke JP, Duggirala R, Hale DE, Blangero J, Stern MP (2000). Genetic basis of acanthosis nigricans in Mexican Americans and its association with phenotypes related to type 2 diabetes. Hum Genet. 106(5):467-72. PMID: 10914675.
26. Arya R, Duggirala R, Williams JT, Almasy L, Blangero J (2001) Power to localize the major gene for disease liability is increased after accounting for the effects of related quantitative phenotypes. Genet Epidemiol. 21 Suppl 1:S774-8. PMID: 11793776.
27. Duggirala R, Blangero J, Almasy L, Arya R, Dyer TD, Williams KL, Leach RJ, O'Connell P, Stern MP (2001) A major locus for fasting insulin concentrations and insulin resistance on chromosome 6q with strong pleiotropic effects on obesity-related phenotypes in nondiabetic Mexican Americans. Am J Hum Genet. 68(5):1149-64. Epub 2001 Mar 29. PMID: 11283790; PMCID: PMC1226096.
28. Mangano A, Gonzalez E, Dhanda R, Catano G, Bamshad M, Bock A, Duggirala R, Williams K, Mummidi S, Clark RA, Ahuja SS, Dolan MJ, Bologna R, Sen L, Ahuja SK (2001) Concordance between the CC chemokine receptor 5 genetic determinants that alter risks of transmission and disease progression in children exposed perinatally to human immunodeficiency virus. J Infect Dis. 183(11):1574-85. Epub 2001 May 2. PMID: 11335892.
29. Arya R, Duggirala R, Almasy L, Rainwater DL, Mahaney MC, Cole S, Dyer TD, Williams K, Leach RJ, Hixson JE, MacCluer JW, O'Connell P, Stern MP, Blangero J (2002) Linkage of high-density lipoprotein-cholesterol concentrations to a locus on chromosome 9p in Mexican Americans. Nat Genet. 30(1):102-5. Epub 2001 Dec 17. PMID: 11743583.
30. Arya R, Blangero J, Williams K, Almasy L, Dyer TD, Leach RJ, O'Connell P, Stern MP, Duggirala R (2002) Factors of insulin resistance syndrome--related phenotypes are linked to genetic locations on chromosomes 6 and 7 in nondiabetic Mexican-Americans. Diabetes. 51(3):841-7. PMID: 11872689.
31. Arya R, Duggirala R, Comuzzie AG, Puppala S, Modem S, Busi BR, Crawford MH (2002) Heritability of anthropometric phenotypes in caste populations of Visakhapatnam, India. Hum Biol. 74(3):325-44. PMID: 12180759.
32. Duggirala R, Uttley M, Williams K, Arya R, Blangero J, Crawford MH (2002) Genetic determination of biological age in the Mennonites of the Midwestern United States. Genet Epidemiol. 23(2):97-109. PMID: 12214304.
33. Hunt KJ, Duggirala R, Göring HH, Williams JT, Almasy L, Blangero J, O'Leary DH, Stern MP (2002) Genetic basis of variation in carotid artery plaque in the San Antonio
15 Family Heart Study. Stroke. 33(12):2775-80. PMID: 12468769.
34. Duggirala R, Almasy L, Blangero J, Jenkinson CP, Arya R, DeFronzo RA, Stern MP, O'Connell P; American Diabetes Association GENNID Study Group (2003) Further evidence for a type 2 diabetes susceptibility locus on chromosome 11q. Genet Epidemiol. 24(3):240-2. PMID: 12652528.
35. Arya R, Lehman D, Hunt KJ, Schneider J, Almasy L, Blangero J, Stern MP, Duggirala R; Framingham Heart Study (2003) Evidence for bivariate linkage of obesity and HDL-C levels in the Framingham Heart Study. BMC Genet. 31;4 Suppl 1:S52. PMID: 14975120; PMCID: PMC1866489.
36. Arya R, Duggirala R, Jenkinson CP, Almasy L, Blangero J, O'Connell P, Stern MP (2004). Evidence of a novel quantitative-trait locus for obesity on chromosome 4p in Mexican Americans. Am J Hum Genet. 74(2):272-82. Epub 2004 Jan 20. Erratum in: Am J Hum Genet. 2004 May;74(5):1080. PMID: 14740316; PMCID: PMC1181925.
37. Lehman DM, Fu DJ, Freeman AB, Hunt KJ, Leach RJ, Johnson-Pais T, Hamlington J, Dyer TD, Arya R, Abboud H, Göring HH, Duggirala R, Blangero J, Konrad RJ, Stern MP (2005). A single nucleotide polymorphism in MGEA5 encoding O-GlcNAc-selective N- acetyl-beta-D glucosaminidase is associated with type 2 diabetes in Mexican Americans. Diabetes. 54(4):1214-21. PMID: 15793264.
38. Lehman DM, Arya R, Blangero J, Almasy L, Puppala S, Dyer TD, Leach RJ, O'Connell P, Stern MP, Duggirala R (2005) Bivariate linkage analysis of the insulin resistance syndrome phenotypes on chromosome 7q. Hum Biol. 77(2):231-46. PMID: 16201139.
39. Hunt KJ, Lehman DM, Arya R, Fowler S, Leach RJ, Göring HH, Almasy L, Blangero J, Dyer TD, Duggirala R, Stern MP (2005) Genome-wide linkage analyses of type 2 diabetes in Mexican Americans: the San Antonio Family Diabetes/Gallbladder Study. Diabetes. 54(9):2655-62. PMID: 16123354.
40. Bauman LE, Almasy L, Blangero J, Duggirala R, Sinsheimer JS, Lange K (2005) Fishing for pleiotropic QTLs in a polygenic sea. Ann Hum Genet. 69(Pt 5):590-611. PMID: 16138917.
41. Rincon-Choles H, Thameem F, Lehman DM, Arya R, Arar N, Duggirala R, Stern MP, Abboud HE. Genetic basis of diabetic nephropathy. Am J Ther. 12(6):555-61. PMID: 16280649.
42. Arya R, Dyer TD, Warren DM, Jenkinson CP, Duggirala R, Almasy L (2005) Effect of genotype x alcoholism interaction on linkage analysis of an alcoholism-related quantitative phenotype. BMC Genet. 30;6 Suppl 1:S120. PMID: 16451578; PMCID: PMC1866817.
43. Krolewski AS, Poznik GD, Placha G, Canani L, Dunn J, Walker W, Smiles A, Krolewski B, Fogarty DG, Moczulski D, Araki S, Makita Y, Ng DP, Rogus J, Duggirala R, Rich SS, Warram JH (2006) A genome-wide linkage scan for genes controlling variation in urinary albumin excretion in type II diabetes. Kidney Int. 69(1):129-36. PMID: 16374433.
16
44. Puppala S, Dodd GD, Fowler S, Arya R, Schneider J, Farook VS, Granato R, Dyer TD, Almasy L, Jenkinson CP, Diehl AK, Stern MP, Blangero J, Duggirala R (2006) A genomewide search finds major susceptibility loci for gallbladder disease on chromosome 1 in Mexican Americans. Am J Hum Genet. 78(3):377-92. Epub 2006 Jan 6. PMID: 16400619; PMCID: PMC1380282.
45. Arya R, Demerath E, Jenkinson CP, Göring HH, Puppala S, Farook V, Fowler S, Schneider J, Granato R, Resendez RG, Dyer TD, Cole SA, Almasy L, Comuzzie AG, Siervogel RM, Bradshaw B, DeFronzo RA, MacCluer J, Stern MP, Towne B, Blangero J, Duggirala R (2006) A quantitative trait locus (QTL) on chromosome 6q influences birth weight in two independent family studies. Hum Mol Genet. 15(10):1569-79. Epub 2006 Apr 12. PMID: 16611675.
46. Diego VP, Göring HH, Cole SA, Almasy L, Dyer TD, Blangero J, Duggirala R, Laston S, Wenger C, Cantu T, Dyke B, North K, Schurr T, Best LG, Devereux RB, Fabsitz RR, Howard BV, MacCluer JW (2006) Fasting insulin and obesity-related phenotypes are linked to chromosome 2p: the Strong Heart Family Study. Diabetes. 55(6):1874-8. PMID: 16731856.
47. Lehman DM, Hamlington J, Hunt KJ, Leach RJ, Arya R, Abboud H, Duggirala R, Blangero J, Göring HH, Stern MP (2006) A novel missense mutation in ADRB3 increases risk for type 2 diabetes in a Mexican American family. Diabetes Metab Res Rev. 22(4):331-6. PMID: 16444766.
48. Lehman DM, Leach RJ, Johnson-Pais T, Hamlington J, Fowler S, Almasy L, Duggirala R, Stern MP, Abboud HE (2006) Evaluation of tight junction protein 1 encoding zona occludens 1 as a candidate gene for albuminuria in a Mexican American population. Exp Clin Endocrinol Diabetes. 114(8):432-7. PMID: 17039425.
49. Richardson DK, Schneider J, Fourcaudot MJ, Rodriguez LM, Arya R, Dyer TD, Almasy L, Blangero J, Stern MP, DeFronzo RA, Duggirala R, Jenkinson CP (2006) Association between variants in the genes for adiponectin and its receptors with insulin resistance syndrome (IRS)-related phenotypes in Mexican Americans. Diabetologia. 49(10):2317- 28. Epub 2006 Aug 29. PMID: 16955209.
50. Warren DM, Stern M, Duggirala R, Dyer TD, Almasy L (2006) Heritability and linkage analysis of hand, foot, and eye preference in Mexican Americans. Laterality. 11(6):508- 24. PMID: 16966240.
51. Placha G, Poznik GD, Dunn J, Smiles A, Krolewski B, Glew T, Puppala S, Schneider J, Rogus JJ, Rich SS, Duggirala R, Warram JH, Krolewski AS (2006) A genome-wide linkage scan for genes controlling variation in renal function estimated by serum cystatin C levels in extended families with type 2 diabetes. Diabetes. 55(12):3358-65. PMID: 17130480.
52. Lehman DM, Hunt KJ, Leach RJ, Hamlington J, Arya R, Abboud HE, Duggirala R, Blangero J, Göring HH, Stern MP (2007) Haplotypes of transcription factor 7-like 2 (TCF7L2) gene and its upstream region are associated with type 2 diabetes and age of
17 onset in Mexican Americans. Diabetes. 56(2):389-93. PMID: 17259383.
53. Lehman DM, Richardson DK, Jenkinson CP, Hunt KJ, Dyer TD, Leach RJ, Arya R, Abboud HE, Blangero J, Duggirala R, Stern MP. P2 promoter variants of the hepatocyte nuclear factor 4alpha gene are associated with type 2 diabetes in Mexican Americans. Diabetes. 2007 Feb;56(2):513-7. PubMed PMID: 17259399.
54. Malhotra A, Elbein SC, Ng MC, Duggirala R, Arya R, Imperatore G, Adeyemo A, Pollin TI, Hsueh WC, Chan JC, Rotimi C, Hanson RL, Hasstedt SJ, Wolford JK (2007) Meta- analysis of genome-wide linkage studies of quantitative lipid traits in families ascertained for type 2 diabetes. Diabetes. 56(3):890-6. PMID: 17327462.
55. Coletta DK, Schneider J, Stern MP, Blangero J, DeFronzo RA, Duggirala R, Jenkinson CP (2007) Association of neuropeptide Y receptor Y5 polymorphisms with dyslipidemia in Mexican Americans. Obesity (Silver Spring). 15(4):809-15. PMID: 17426313.
56. Iyengar SK, Abboud HE, Goddard KA, Saad MF, Adler SG, Arar NH, Bowden DW, Duggirala R, Elston RC, Hanson RL, Ipp E, Kao WH, Kimmel PL, Klag MJ, Knowler WC, Meoni LA, Nelson RG, Nicholas SB, Pahl MV, Parekh RS, Quade SR, Rich SS, Rotter JI, Scavini M, Schelling JR, Sedor JR, Sehgal AR, Shah VO, Smith MW, Taylor KD, Winkler CA, Zager PG, Freedman BI; Family Investigation of Nephropathy and Diabetes Research Group (2007) Genome-wide scans for diabetic nephropathy and albuminuria in multiethnic populations: the family investigation of nephropathy and diabetes (FIND). Diabetes. 56(6):1577-85. Epub 2007 Mar 15. PMID: 17363742.
57. Saunders CL, Chiodini BD, Sham P, Lewis CM, Abkevich V, Adeyemo AA, de Andrade M, Arya R, Berenson GS, Blangero J, Boehnke M, Borecki IB, Chagnon YC, Chen W, Comuzzie AG, Deng HW, Duggirala R, Feitosa MF, Froguel P, Hanson RL, Hebebrand J, Huezo-Dias P, Kissebah AH, Li W, Luke A, Martin LJ, Nash M, Ohman M, Palmer LJ, Peltonen L, Perola M, Price RA, Redline S, Srinivasan SR, Stern MP, Stone S, Stringham H, Turner S, Wijmenga C, Collier DA (2007) Meta-analysis of genome-wide linkage studies in BMI and obesity. Obesity (Silver Spring). 15(9):2263-75. PMID: 17890495.
58. Puppala S, Arya R, Thameem F, Arar NH, Bhandari K, Lehman DM, Schneider J, Fowler S, Farook VS, Diego VP, Almasy L, Blangero J, Stern MP, Duggirala R, Abboud HE (2007) Genotype by diabetes interaction effects on the detection of linkage of glomerular filtration rate to a region on chromosome 2q in Mexican Americans. Diabetes. 56(11):2818-28. Epub 2007 Aug 13. PMID: 17698600.
59. Habib SL, Danial E, Nath S, Schneider J, Jenkinson CP, Duggirala R, Abboud HE, Thameem F (2008) Genetic polymorphisms in OGG1 and their association with angiomyolipoma, a benign kidney tumor in patients with tuberous sclerosis. Cancer Biol Ther. 7(1):23-7. Epub 2007 Oct 8. PMID: 17932460.
60. Thameem F, Puppala S, Arar NH, Farook VS, Stern MP, Blangero J, Duggirala R, Abboud HE (2008) The Cys(311)Ser polymorphism of paraoxonase 2 (PON2) is associated with albumin-to-creatinine ratio (ACR) in Mexican Americans. Nephrol Dial Transplant. 23(1):416-7. Epub 2007 Oct 15. PMID: 17940058.
18
61. Guan W, Pluzhnikov A, Cox NJ, Boehnke M; International Type 2 Diabetes Linkage Analysis Consortium [includes Duggirala R and others as collaborators] (2007) Meta- analysis of 23 type 2 diabetes linkage studies from the International Type 2 Diabetes Linkage Analysis Consortium. Hum Hered. 2008;66(1):35-49. doi: 10.1159/000114164. Epub 2007 Jan 28. Erratum in: Hum Hered. 2008;66(4):237. PMID: 18223311; PMC2855874.
62. Keenan HA, Poznik GD, Varo N, Schneider J, Almasy L, Warram JH, Duggirala R, Schoenbeck U, Krolewski AS, Doria A (2008) Identification of a locus modulating serum C-reactive protein levels on chromosome 5p15. Atherosclerosis. 2008 Feb;196(2):863- 70. Epub 2007 Mar 7. PubMed PMID: 17343862; PubMed Central PMCID: PMC2335172.
63. Thameem F, Puppala S, Arar N, Blangero J, Stern MP, Duggirala R, Abboud HE (2008) Genetic polymorphisms in the renin-angiotensin system (RAS) genes and their association analysis with type 2 diabetes and related traits in Mexican Americans. Diabetes Res Clin Pract. Feb;79(2):e14-6. Epub 2007 Oct 23. PubMed PMID: 17936396.
64. Samudrala N, Farook VS, Dodd GD, Puppala S, Schneider J, Fowler S, Granato R, Dyer TD, Arya R, Almasy L, Jenkinson CP, Diehl AK, Blangero J, Duggirala R (2008) Autosomal genome-wide linkage analysis to identify loci for gallbladder wall thickness in Mexican Americans. Hum Biol. 80(1):11-28. PMID: 18505042.
65. Thameem F, Puppala S, Arar NH, Stern MP, Blangero J, Duggirala R, Abboud HE (2008) Endothelial nitric oxide synthase (eNOS) gene polymorphisms and their association with type 2 diabetes-related traits in Mexican Americans. Diab Vasc Dis Res. 5(2):109-13. doi: 10.3132/dvdr.2008.018. PMID: 18537098; PMCID: PMC3336872.
66. Jenkinson CP, Coletta DK, Flechtner-Mors M, Hu SL, Fourcaudot MJ, Rodriguez LM, Schneider J, Arya R, Stern MP, Blangero J, Duggirala R, DeFronzo RA (2008) Association of genetic variation in ENPP1 with obesity-related phenotypes. Obesity (Silver Spring). 16(7):1708-13. doi: 10.1038/oby.2008.262. Epub 2008 May 8. PMID: 18464750.
67. Arar NH, Freedman BI, Adler SG, Iyengar SK, Chew EY, Davis MD, Satko SG, Bowden DW, Duggirala R, Elston RC, Guo X, Hanson RL, Igo RP Jr, Ipp E, Kimmel PL, Knowler WC, Molineros J, Nelson RG, Pahl MV, Quade SR, Rasooly RS, Rotter JI, Saad MF, Scavini M, Schelling JR, Sedor JR, Shah VO, Zager PG, Abboud HE; Family Investigation of Nephropathy and Diabetes Research Group (2008) Heritability of the severity of diabetic retinopathy: the FIND-Eye study. Invest Ophthalmol Vis Sci. 49(9):3839-45. doi: 10.1167/iovs.07-1633. PMID: 18765632; PMCID: PMC2583147.
68. Coletta DK, Schneider J, Hu SL, Dyer TD, Puppala S, Farook VS, Arya R, Lehman DM, Blangero J, DeFronzo RA, Duggirala R, Jenkinson CP (2009) Genome-wide linkage scan for genes influencing plasma triglyceride levels in the Veterans Administration Genetic Epidemiology Study. Diabetes. 58(1):279-84. doi: 10.2337/db08-0491. Epub 2008 Oct 17. PMID: 18931038; PMCID: PMC2606886.
19
69. Thameem F, Puppala S, He X, Arar NH, Stern MP, Blangero J, Duggirala R, Abboud HE (2009) Evaluation of gremlin 1 (GREM1) as a candidate susceptibility gene for albuminuria-related traits in Mexican Americans with type 2 diabetes mellitus. Metabolism. 58(10):1496-502. doi: 10.1016/j.metabol. 2009.04.039. Epub 2009 Jul 4. PMID: 19577778; PMCID: PMC2913546.
70. Malhotra A, Igo RP Jr, Thameem F, Kao WH, Abboud HE, Adler SG, Arar NH, Bowden DW, Duggirala R, Freedman BI, Goddard KA, Ipp E, Iyengar SK, Kimmel PL, Knowler WC, Kohn O, Leehey D, Meoni LA, Nelson RG, Nicholas SB, Parekh RS, Rich SS, Chen YD, Saad MF, Scavini M, Schelling JR, Sedor JR, Shah VO, Taylor KD, Thornley-Brown D, Zager PG, Horvath A, Hanson RL; Family Investigation of Nephropathy and Diabetes Research Group (2009) Genome-wide linkage scans for type 2 diabetes mellitus in four ethnically diverse populations-significant evidence for linkage on chromosome 4q in African Americans: the Family Investigation of Nephropathy and Diabetes Research Group. Diabetes Metab Res Rev. 25(8):740-7. doi: 10.1002/dmrr.1031. PMID: 19795399; PMCID: PMC2783577.
71. Kochunov P, Glahn D, Winkler A, Duggirala R, Olvera RL, Cole S, Dyer TD, Almasy L, Fox PT, Blangero J (2009) Analysis of genetic variability and whole genome linkage of whole-brain, subcortical, and ependymal hyperintense white matter volume. Stroke. 40(12):3685-90. doi: 10.1161/STROKEAHA.109.565390. Epub 2009 Oct 15. PMID: 19834011; PMCID: PMC2787844.
72. Arya R, Hare E, Del Rincon I, Jenkinson CP, Duggirala R, Almasy L, Escalante A (2009) Effects of covariates and interactions on a genome-wide association analysis of rheumatoid arthritis. BMC Proc. 2009 Dec 15;3 Suppl 7:S84. PMID: 20018080; PMCID: PMC2795987.
73. Glahn DC, Winkler AM, Kochunov P, Almasy L, Duggirala R, Carless MA, Curran JC, Olvera RL, Laird AR, Smith SM, Beckmann CF, Fox PT, Blangero J (2010) Genetic control over the resting brain. Proc Natl Acad Sci U S A. 19;107(3):1223-8. doi: 10.1073/pnas.0909969107. PMID: 20133824; PMCID: PMC2824276.
74. Karlsgodt KH, Kochunov P, Winkler AM, Laird AR, Almasy L, Duggirala R, Olvera RL, Fox PT, Blangero J, Glahn DC (2010) A multimodal assessment of the genetic control over working memory. J Neurosci. 30(24):8197-202. doi: 10.1523/JNEUROSCI.0359- 10.2010. PMID: 20554870; PMCID: PMC2894480.
75. Thameem F, Puppala S, Lehman DM, Stern MP, Blangero J, Abboud HE, Duggirala R, Habib SL (2010) The Ser(326)Cys polymorphism of 8-Oxoguanine Glycosylase 1 (OGG1) is associated with type 2 diabetes in Mexican Americans. Hum Hered. 70(2):97- 101. [Epub ahead of print] PMID: 20606456; PMCID: PMC3083264.
76. Kochunov P, Glahn D, Lancaster J, Winkler A, Kent JW Jr, Olvera RL, Cole SA, Dyer TD, Almasy L, Duggirala R, Fox PT, Blangero J (2010) Whole brain and regional hyperintense white matter volume and blood pressure: overlap of genetic loci produced by bivariate, whole-genome linkage analyses. Stroke. 41(10):2137-42. doi:10.1161/ STROKEAHA. 110.590943. Epub 2010 Aug 19. PMID: 20724716; PMCID:
20 PMC3084627.
77. Winkler AM, Kochunov P, Blangero J, Almasy L, Zilles K, Fox PT, Duggirala R, Glahn DC (2010) Cortical thickness or grey matter volume? The importance of selecting the phenotype for imaging genetics studies. Neuroimage. 2010 Nov 15;53(3):1135-46. doi: 10.1016/j.neuroimage.2009.12.028. Epub 2009 Dec 16. PMID: 20006715; PMCID: PMC2891595.
78. Kochunov P, Glahn DC, Lancaster JL, Winkler AM, Smith S, Thompson PM, Almasy L, Duggirala R, Fox PT, Blangero J (2010) Genetics of microstructure of cerebral white matter using diffusion tensor imaging. Neuroimage. 53(3):1109-16. doi:10.1016/ j.neuroimage.2010.01.078. Epub 2010 Jan 29. PMID: 20117221; PMCID: PMC2888778.
79. Rogers J, Kochunov P, Zilles K, Shelledy W, Lancaster J, Thompson P, Duggirala R, Blangero J, Fox PT, Glahn DC (2010) On the genetic architecture of cortical folding and brain volume in primates. Neuroimage. 53(3):1103-8. doi: 10.1016/j.neuroimage. 2010.02.020. Epub 2010 Feb 20. PMID: 20176115; PMCID: PMC3137430.
80. Puppala S, Coletta DK, Schneider J, Hu SL, Farook VS, Dyer TD, Arya R, Blangero J, Duggirala R, DeFronzo RA, Jenkinson CP (2011) Genome-wide linkage screen for systolic blood pressure in the Veterans Administration Genetic Epidemiology Study (VAGES) of Mexican-Americans and confirmation of a major susceptibility locus on chromosome 6q14.1. Hum Hered. 2011;71(1):1-10. doi: 10.1159/000323143. Epub 2011 Feb 5. PubMed PMID: 21293138; PubMed Central PMCID: PMC3152483.
81. Igo RP Jr, Iyengar SK, Nicholas SB, Goddard KA, Langefeld CD, Hanson RL, Duggirala R, Divers J, Abboud H, Adler SG, Arar NH, Horvath A, Elston RC, Bowden DW, Guo X, Ipp E, Kao WH, Kimmel PL, Knowler WC, Meoni LA, Molineros J, Nelson RG, Pahl MV, Parekh RS, Rasooly RS, Schelling JR, Shah VO, Smith MW, Winkler CA, Zager PG, Sedor JR, Freedman BI; Family Investigation of Nephropathy and Diabetes Research Group (2011) Genomewide linkage scan for diabetic renal failure and albuminuria: the FIND study. Am J Nephrol. 2011;33(5):381-9. doi: 10.1159/000326763. Epub 2011 Mar 31. PMID: 21454968; PMCID: PMC3078269.
82. Rubicz R, Leach CT, Kraig E, Dhurandhar NV, Duggirala R, Blangero J, Yolken R, Göring HH (2011) Genetic factors influence serological measures of common infections. Hum Hered. 72(2):133-41. doi: 10.1159/000331220. Epub 2011 Oct 11. PMID: 21996708; PMCID: PMC3214928.
83. Kochunov P, Glahn DC, Lancaster J, Winkler A, Karlsgodt K, Olvera RL, Curran JE, Carless MA, Dyer TD, Almasy L, Duggirala R, Fox PT, Blangero J (2011) Blood pressure and cerebral white matter share common genetic factors in Mexican Americans. Hypertension. 57(2):330-5. doi: 10.1161/HYPERTENSIONAHA.110.162206. Epub 2010 Dec 6. PMID: 21135356; PMCID: PMC3024472.
84. Olvera RL, Bearden CE, Velligan DI, Almasy L, Carless MA, Curran JE, Williamson DE, Duggirala R, Blangero J, Glahn DC (2011) Common genetic influences on depression, alcohol, and substance use disorders in Mexican-American families. Am J Med Genet B Neuropsychiatr Genet. 156B(5):561-8. doi: 10.1002/ajmg.b.31196. Epub 2011 May 6.
21 PMID: 21557468; PMCID: PMC3112290.
85. Beuten J, Halder I, Fowler SP, Goring HH, Duggirala R, Arya R, Thompson IM, Leach RJ, Lehman DM (2011) Wide disparity in genetic admixture among Mexican Americans from San Antonio, TX. Ann Hum Genet. 75(4):529-38. doi: 10.1111/j.1469- 1809.2011.00655.x. Epub 2011 May 18. PMID: 21592109; PMCID: PMC3115480.
86. Sobrin L, Green T, Sim X, Jensen RA, Tai ES, Tay WT, Wang JJ, Mitchell P, Sandholm N, Liu Y, Hietala K, Iyengar SK; Family Investigation of Nephropathy and Diabetes-Eye Research Group [includes Duggirala R and others as collaborators], Brooks M, Buraczynska M, Van Zuydam N, Smith AV, Gudnason V, Doney AS, Morris AD, Leese GP, Palmer CN; Wellcome Trust Case Control Consortium 2, Swaroop A, Taylor HA Jr, Wilson JG, Penman A, Chen CJ, Groop PH, Saw SM, Aung T, Klein BE, Rotter JI, Siscovick DS, Cotch MF, Klein R, Daly MJ, Wong TY (2011) Candidate gene association study for diabetic retinopathy in persons with type 2 diabetes: the Candidate gene Association Resource (CARe). Invest Ophthalmol Vis Sci. 52(10):7593-602. doi: 10.1167/iovs.11-7510. PMID: 21873659; PMCID: PMC3183981.
87. Carless MA, Glahn DC, Johnson MP, Curran JE, Bozaoglu K, Dyer TD, Winkler AM, Cole SA, Almasy L, MacCluer JW, Duggirala R, Moses EK, Göring HH, Blangero J (2011) Impact of DISC1 variation on neuroanatomical and neurocognitive phenotypes. Mol Psychiatry. 16(11):1096-104, 1063. doi: 10.1038/mp.2011.37. Epub 2011 Apr 12. PMID: 21483430; PMCID: PMC3135724.
88. Thameem F, Puppala S, Arar NH, Blangero J, Duggirala R, Abboud HE (2011) Genetic variants in transient receptor potential cation channel, subfamily M 1 (TRPM1) and their risk of albuminuria-related traits in Mexican Americans. Clin Chim Acta. 412(23- 24):2058-62. doi: 10.1016/j.cca.2011.03.024. Epub 2011 Apr 1. PMID: 21439949; PMCID: PMC3206641.
89. Kent JW Jr, Farook V, Göring HH, Dyer TD, Almasy L, Duggirala R, Blangero J (2011) Do rare variant genotypes predict common variant genotypes? BMC Proc. 5 Suppl 9:S87. doi: 10.1186/1753-6561-5-S9-S87. PMID: 22373504; PMCID: PMC3287928.
90. Glahn DC, Curran JE, Winkler AM, Carless MA, Kent JW Jr, Charlesworth JC, Johnson MP, Göring HH, Cole SA, Dyer TD, Moses EK, Olvera RL, Kochunov P, Duggirala R, Fox PT, Almasy L, Blangero J (2012) High dimensional endophenotype ranking in the search for major depression risk genes. Biol Psychiatry. 71(1):6-14. doi: 10.1016/ j.biopsych. 2011.08.022. Epub 2011 Oct 7. PMID: 21982424; PMCID: PMC3230692.
91. Kochunov P, Glahn DC, Hong LE, Lancaster J, Curran JE, Johnson MP, Winkler AM, Holcomb HH, Kent JW Jr, Mitchell B, Kochunov V, Olvera RL, Cole SA, Dyer TD, Moses EK, Goring H, Almasy L, Duggirala R, Blangero J (2012) P-selectin Expression Tracks Cerebral Atrophy in Mexican-Americans. Front Genet. 3:65. doi: 10.3389/fgene. 2012.00065. PMID: 22558002; PMCID: PMC3340599.
92. Bostrom MA, Kao WH, Li M, Abboud HE, Adler SG, Iyengar SK, Kimmel PL, Hanson RL, Nicholas SB, Rasooly RS, Sedor JR, Coresh J, Kohn OF, Leehey DJ, Thornley-Brown D, Bottinger EP, Lipkowitz MS, Meoni LA, Klag MJ, Lu L, Hicks PJ, Langefeld CD,
22 Parekh RS, Bowden DW, Freedman BI; Family Investigation of Nephropathy and Diabetes (FIND) Research Group [includes Duggirala R and others as collaborators] (2012) Genetic association and gene-gene interaction analyses in African American dialysis patients with nondiabetic nephropathy. Am J Kidney Dis. 59(2):210-21. doi: 10.1053/j.ajkd.2011.09.020. Epub 2011 Nov 25. PMID: 22119407; PMCID: PMC3259209.
93. Stein JL, et al., [multi-author paper including Duggirala R] Enhancing Neuro Imaging Genetics through Meta-Analysis Consortium (2012) Identification of common variants associated with human hippocampal and intracranial volumes. Nat Genet. 44(5):552-61. doi: 10.1038/ng.2250. PMID: 22504417; PMCID: PMC3635491.
94. Bis JC, DeCarli C, Smith AV, van der Lijn F,…..Thompson PM; Enhancing Neuro Imaging Genetics through Meta-Analysis Consortium [includes Duggirala R and others as collaborators], Nalls MA, Uitterlinden AG, Au R, Elbaz A, Beare RJ, van Swieten JC, Lopez OL, Harris TB, Chouraki V, Breteler MM, De Jager PL, Becker JT, Vernooij MW, Knopman D, Fazekas F, Wolf PA, van der Lugt A, Gudnason V, Longstreth WT Jr, Brown MA, Bennett DA, van Duijn CM, Mosley TH, Schmidt R, Tzourio C, Launer LJ, Ikram MA, Seshadri S; Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (2012) Common variants at 12q14 and 12q24 are associated with hippocampal volume. Nat Genet. 44(5):545-51. doi: 10.1038/ng.2237. PMID: 22504421; PMCID: PMC3427729.
95. Thameem F, Puppala S, Schneider J, Bhandari B, Arya R, Arar NH, Vasylyeva TL, Farook VS, Fowler S, Almasy L, Blangero J, Duggirala R, Abboud HE (2012) The Gly(972)Arg variant of human IRS1 gene is associated with variation in glomerular filtration rate likely through impaired insulin receptor signaling. Diabetes. 61(9):2385-93. doi: 10.2337/db11-1078. Epub 2012 May 22. PMID: 22617042; PMCID: PMC3425400.
96. Farook VS, Puppala S, Schneider J, Fowler SP, Chittoor G, Dyer TD, Allayee H, Cole SA, Arya R, Black MH, Curran JE, Almasy L, Buchanan TA, Jenkinson CP, Lehman DM, Watanabe RM, Blangero J, Duggirala R (2012) Metabolic syndrome is linked to chromosome 7q21 and associated with genetic variants in CD36 and GNAT3 in Mexican Americans. Obesity (Silver Spring). 20(10):2083-92. doi: 10.1038/oby.2012.74. Epub 2012 Mar 29. PMID: 22456541.
97. S. Yaseen Saheb, D. Xaviour, B. V. Raviprasad, Md. Salman, S. Dasgupta, M. A. Shekar, H Basavana Gowdappa, K. Raghothama Rao, Duggirala R, P. B. S. V. Padmanabham, B. N. Sarkar, D. Lokanath, S. Samanta, A. Alam (2012) Prevalence of type 2 diabetes and obesity in Gangadikara Vokkaligas of Mysore, Karnataka. Journal of the Anthropological Survey of India 61:193-209.
98. Mamtani M, Kulkarni H, Dyer TD, Almasy L, Mahaney MC, Duggirala R, Comuzzie AG, Blangero J, Curran JE (2013) Waist circumference independently associates with the risk of insulin resistance and type 2 diabetes in mexican american families. PLoS One. 8(3):e59153. doi: 10.1371/journal.pone.0059153. Epub 2013 Mar 11. PMID: 23536864; PMCID: PMC3594157.
99. Farook VS, Coletta DK, Puppala S, Schneider J, Chittoor G, Hu SL, Winnier DA, Norton
23 L, Dyer TD, Arya R, Cole SA, Carless M, Göring HH, Almasy L, Mahaney MC, Comuzzie AG, Curran JE, Blangero J, Duggirala R, Lehman DM, Jenkinson CP, DeFronzo RA (2013) Linkage of type 2 diabetes on chromosome 9p24 in Mexican Americans: additional evidence from the Veterans Administration Genetic Epidemiology Study (VAGES). Hum Hered. 76(1):36-46. doi: 10.1159/000354849. Epub 2013 Sep 21. PMID: 24060607; PMCID: PMC3919448.
100. Curran JE, McKay DR, Winkler AM, Olvera RL, Carless MA, Dyer TD, Kent JW Jr, Kochunov P, Sprooten E, Knowles EE, Comuzzie AG, Fox PT, Almasy L, Duggirala R, Blangero J, Glahn DC (2013) Identification of pleiotropic genetic effects on obesity and brain anatomy. Hum Hered. 2013;75(2-4):136-43. doi: 10.1159/000353953. Epub 2013 Sep 27. PubMed PMID: 24081229; PubMed Central PMCID: PMC3889074.
101. Mamtani M, Kulkarni H, Dyer TD, Almasy L, Mahaney MC, Duggirala R, Comuzzie AG, Blangero J, Curran JE (2013). Correction: Waist circumference independently associates with the risk of insulin resistance and type 2 diabetes in Mexican American families. PLoS One. 8(11). doi: 10.1371/annotation/86d53ad4-5b90-41dc-a027- 07a155412f15. PMID: 24223682; PMCID: PMC3817259.
102. Thameem F, Igo RP Jr, Freedman BI, Langefeld C, Hanson RL, Schelling JR, Elston RC, Duggirala R, Nicholas SB, Goddard KA, Divers J, Guo X, Ipp E, Kimmel PL, Meoni LA, Shah VO, Smith MW, Winkler CA, Zager PG, Knowler WC, Nelson RG, Pahl MV, Parekh RS, Kao WH, Rasooly RS, Adler SG, Abboud HE, Iyengar SK, Sedor JR; Family Investigation of Nephropathy and Diabetes Research Group (2013) A genome-wide search for linkage of estimated glomerular filtration rate (eGFR) in the Family Investigation of Nephropathy and Diabetes (FIND). PLoS One. 8(12):e81888. doi: 10.1371/journal.pone.0081888. PMID: 24358131; PMCID: PMC3866106.
103. Kochunov P, Glahn DC, Rowland LM, Olvera RL, Winkler A, Yang YH, Sampath H, Carpenter WT, Duggirala R, Curran J, Blangero J, Hong LE (2013) Testing the hypothesis of accelerated cerebral white matter aging in schizophrenia and major depression. Biol Psychiatry. 73(5):482-91. doi: 10.1016/j.biopsych. 2012. 10.002. Epub 2012 Nov 28. PMID: 23200529; PMCID: PMC3645491.
104. Blackburn A, Göring HH, Dean A, Carless MA, Dyer T, Kumar S, Fowler S, Curran JE, Almasy L, Mahaney M, Comuzzie A, Duggirala R, Blangero J, Lehman DM (2013) Utilizing extended pedigree information for discovery and confirmation of copy number variable regions among Mexican Americans. Eur J Hum Genet. 21(4):404-9. doi: 10.1038/ejhg.2012.188. Epub 2012 Aug 22. PMID: 22909773; PMCID: PMC3598314.
105. Fowler SP, Puppala S, Arya R, Chittoor G, Farook VS, Schneider J, Resendez RG, Upadhayay RP, Vandeberg J, Hunt KJ, Bradshaw B, Cersosimo E, Vandeberg JL, Almasy L, Curran JE, Comuzzie AG, Lehman DM, Jenkinson CP, Lynch JL, DeFronzo RA, Blangero J, Hale DE, Duggirala R (2013) Genetic epidemiology of cardiometabolic risk factors and their clustering patterns in Mexican American children and adolescents: the SAFARI Study. Hum Genet. 132(9):1059-71. doi: 10.1007/s00439-013-1315-2. Epub 2013 Jun 5. PMID: 23736306; PMCID: PMC3845827.
106. Chittoor G, Farook VS, Puppala S, Fowler SP, Schneider J, Dyer TD, Cole SA, Lynch
24 JL, Curran JE, Almasy L, MacCluer JW, Comuzzie AG, Hale DE, Ramamurthy RS, Dudley DJ, Moses EK, Arya R, Lehman DM, Jenkinson CP, Bradshaw BS, DeFronzo RA, Blangero J, Duggirala R (2013) Localization of a major susceptibility locus influencing preterm birth. Mol Hum Reprod. 19(10):687-96. doi: 10.1093/molehr/gat036. Epub 2013 May 20. PMID: 23689979; PMCID: PMC3779004.
107. Jahanshad N, Kochunov PV, Sprooten E, Mandl RC, Nichols TE, Almasy L, Blangero J, Brouwer RM, Curran JE, de Zubicaray GI, Duggirala R, Fox PT, Hong LE, Landman BA, Martin NG, McMahon KL, Medland SE, Mitchell BD, Olvera RL, Peterson CP, Starr JM, Sussmann JE, Toga AW, Wardlaw JM, Wright MJ, Hulshoff Pol HE, Bastin ME, McIntosh AM, Deary IJ, Thompson PM, Glahn DC (2013) Multi-site genetic analysis of diffusion images and voxelwise heritability analysis: a pilot project of the ENIGMA-DTI working group. Neuroimage. 81:455-69. doi: 10.1016/j.neuroimage.2013.04.061. Epub 2013 Apr 28. Erratum in: Neuroimage. 2014 Apr 15;90:470-1. PMID: 23629049; PMCID: PMC3729717.
108. Kochunov P, Charlesworth J, Winkler A, Hong LE, Nichols TE, Curran JE, Sprooten E, Jahanshad N, Thompson PM, Johnson MP, Kent JW Jr, Landman BA, Mitchell B, Cole SA, Dyer TD, Moses EK, Goring HH, Almasy L, Duggirala R, Olvera RL, Glahn DC, Blangero J (2013) Transcriptomics of cortical gray matter thickness decline during normal aging. Neuroimage. 82:273-83. doi: 10.1016/j.neuroimage.2013.05.066. Epub 2013 May 24. PMID: 23707588; PMCID: PMC3759649.
109. Glahn DC, Kent JW Jr, Sprooten E, Diego VP, Winkler AM, Curran JE, McKay DR, Knowles EE, Carless MA, Göring HH, Dyer TD, Olvera RL, Fox PT, Almasy L, Charlesworth J, Kochunov P, Duggirala R, Blangero J (2013) Genetic basis of neurocognitive decline and reduced white-matter integrity in normal human brain aging. Proc Natl Acad Sci U S A. 110(47):19006-11. doi: 10.1073/pnas. 1313735110. Epub 2013 Nov 4. PMID: 24191011; PMCID: PMC3839730.
110. Chittoor G, Arya R, Farook VS, David R, Puppala S, Resendez RG, Rivera-Chavira BE, Leal-Berumen I, Zenteno-Cuevas R, López-Alvarenga JC, Bastarrachea RA, Curran JE, Dhandayuthapani S, Gonzalez L, Blangero J, Crawford MH, Vlasich EM, Escobedo LG, Duggirala R (2013) Epidemiologic investigation of tuberculosis in a Mexican population from Chihuahua State, Mexico: a pilot study. Tuberculosis (Edinb). 93 Suppl:S71-7. doi: 10.1016/S1472-9792(13)70014-3. PMID: 24388653.
111. Sridhar GR, Duggirala R, Padmanabhan S (2013) Emerging face of genetics, genomics and diabetes. Int J Diabetes Dev Ctries 33(4):183–185; DOI 10.1007/s13410-013-0164- 9.
112. Mamtani M, Kulkarni H, Dyer TD, Almasy L, Mahaney MC, Duggirala R, Comuzzie AG, Blangero J, Curran JE (2014) Waist circumference is genetically correlated with incident type 2 diabetes in Mexican-American families. Diabet Med. 31(1):31-5. doi: 10.1111/dme.12266. Epub 2013 Jul 13. PMID: 23796311; PMCID: PMC3849209.
113. Knowles EE, Carless MA, de Almeida MA, Curran JE, McKay DR, Sprooten E, Dyer TD, Göring HH, Olvera R, Fox P, Almasy L, Duggirala R, Kent JW Jr, Blangero J, Glahn DC (2014) Genome-wide significant localization for working and spatial memory: Identifying
25 genes for psychosis using models of cognition. Am J Med Genet B Neuropsychiatr Genet. 165(1):84-95. doi: 10.1002/ajmg.b.32211. Epub 2013 Nov 14. PMID: 24243780.
114. SIGMA Type 2 Diabetes Consortium, Williams AL, (Consortium, multi-author paper) ….. Puppala S, Farook VS, Thameem F, Abboud HE, DeFronzo RA, Jenkinson CP, Lehman DM, Curran JE, Blangero J, Duggirala R, Burtt NP, Cortes ML, Altshuler D, Florez JC, Haiman CA, Henderson BE, Aguilar-Salinas CA, González-Villalpando C, Orozco L, Tusié-Luna T (2014) Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico. Nature. 506(7486):97-101. doi: 10.1038/nature 12828. Epub 2013 Dec 25. PMID: 24390345.
115. Mamtani M, Meikle PJ, Kulkarni H, Weir JM, Barlow CK, Jowett JB, Bellis C, Dyer TD, Almasy L, Mahaney MC, Duggirala R, Comuzzie AG, Blangero J, Curran JE (2014) Plasma dihydroceramide species associate with waist circumference in Mexican American families. Obesity (Silver Spring). 22(3):950-6. doi: 10.1002/oby.20598. Epub 2013 Sep 20. PMID: 23929697; PMCID: PMC3918249.
116. Kochunov P, Jahanshad N, Sprooten E, Nichols TE, Mandl RC, Almasy L, Booth T, Brouwer RM, Curran JE, de Zubicaray GI, Dimitrova R, Duggirala R, Fox PT, Elliot Hong L, Landman BA, Lemaitre H, Lopez LM, Martin NG, McMahon KL, Mitchell BD, Olvera RL, Peterson CP, Starr JM, Sussmann JE, Toga AW, Wardlaw JM, Wright MJ, Wright SN, Bastin ME, McIntosh AM, Boomsma DI, Kahn RS, den Braber A, de Geus EJ, Deary IJ, Hulshoff Pol HE, Williamson DE, Blangero J, van 't Ent D, Thompson PM, Glahn DC (2014) Multi-site study of additive genetic effects on fractional anisotropy of cerebral white matter: Comparing meta and megaanalytical approaches for data pooling. Neuroimage. 2014 Jul 15;95:136-50. doi: 10.1016/j.neuroimage.2014.03.033. [Epub ahead of print] PMID: 24657781.
117. Flannick J, Thorleifsson G, Beer NL, Jacobs SB, Grarup N, Burtt NP, Mahajan A, Fuchsberger C, Atzmon G, Benediktsson R, Blangero J, Bowden DW, Brandslund I, Brosnan J, Burslem F, Chambers J, Cho YS, Christensen C, Douglas DA, Duggirala R, Dymek Z, Farjoun Y, Fennell T, Fontanillas P, Forsén T, Gabriel S, Glaser B, Gudbjartsson DF, Hanis C, Hansen T, Hreidarsson AB, Hveem K, Ingelsson E, Isomaa B, Johansson S, Jørgensen T, Jørgensen ME, Kathiresan S, Kong A, Kooner J, Kravic J, Laakso M, Lee JY, Lind L, Lindgren CM, Linneberg A, Masson G, Meitinger T, Mohlke KL, Molven A, Morris AP, Potluri S, Rauramaa R, Ribel-Madsen R, Richard AM, Rolph T, Salomaa V, Segrè AV, Skärstrand H, Steinthorsdottir V, Stringham HM, Sulem P, Tai ES, Teo YY, Teslovich T, Thorsteinsdottir U, Trimmer JK, Tuomi T, Tuomilehto J, Vaziri- Sani F, Voight BF, Wilson JG, Boehnke M, McCarthy MI, Njølstad PR, Pedersen O; Go- T2D Consortium; T2D-GENES Consortium, Groop L, Cox DR, Stefansson K, Altshuler D (2014) Loss-of-function mutations in SLC30A8 protect against type 2 diabetes. Nat Genet. 46(4):357-63. doi: 10.1038/ng.2915. Epub 2014 Mar 2. PMID: 24584071.
118. Kos MZ, Glahn DC, Carless MA, Olvera R, McKay DR, Quillen EE, Gelernter J, Chen XD, Deng HW, Kent JW, Dyer TD, Göring HH, Curran JE, Duggirala R, Blangero J, Almasy L (2014) Novel QTL at chromosome 6p22 for alcohol consumption: Implications for the genetic liability of alcohol use disorders. Am J Med Genet B Neuropsychiatr Genet. Apr 1. doi: 10.1002/ajmg.b.32231. [Epub ahead of print] PMID: 24692236.
26 119. Sprooten E, Knowles EE, McKay DR, Göring HH, Curran JE, Kent JW Jr, Carless MA, Dyer TD, Drigalenko EI, Olvera RL, Fox PT, Almasy L, Duggirala R, Kochunov P, Blangero J, Glahn DC (2014) Common genetic variants and gene expression associated with white matter microstructure in the human brain. Neuroimage. Aug 15;97:252-61. doi:10.1016/j.neuroimage.2014.04.021. [Epub ahead of print] PMID: 24736177.
120. McKay DR, Knowles EE, Winkler AA, Sprooten E, Kochunov P, Olvera RL, Curran JE, Kent JW Jr, Carless MA, Göring HH, Dyer TD, Duggirala R, Almasy L, Fox PT, Blangero J, Glahn DC (2014) Influence of age, sex and genetic factors on the human brain. Brain Imaging Behav. Jun;8(2):143-52. doi: 10.1007/s11682-013-9277-5. PMID: 24297733.
121. Thompson PM, Stein JL, Medland SE, Hibar DP, (Consortium, Multi-author paper) ….. Duggirala R,…..Alzheimer’s Disease Neuroimaging Initiative, EPIGEN Consortium, IMAGEN Consortium, Saguenay Youth Study (SYS) Group (2014) The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic ata. Brain Imaging Behav. 8(2):153-82. doi: 10.1007/s11682-013-9269-5. PMID: 24399358.
122. Chouinard-Decorte F, McKay DR, Reid A, Khundrakpam B, Zhao L, Karama S, Rioux P, Sprooten E, Knowles E, Kent JW Jr, Curran JE, Göring HH, Dyer TD, Olvera RL, Kochunov P, Duggirala R, Fox PT, Almasy L, Blangero J, Bellec P, Evans AC, Glahn DC (2014) Heritable changes in regional cortical thickness with age. Brain Imaging Behav. 8(2):208-16. doi: 10.1007/s11682-014-9296-x. Epub 2014 Apr 22. PMID: 24752552.
123. Almeida M, Peralta J, Farook VS, Puppala S, Kent JW Jr, Duggirala R, Blangero J (2014) Pedigree-based random effect tests to screen gene pathways. BMC Proceedings 2014, 8(Suppl 1):S100 doi:10.1186/1753-6561-8-S1-S100. eCollection 2014. PubMed PMID: 25519354; PubMed Central PMCID: PMC4143680.
124. Quillen EE, Voruganti VS, Chittoor G, Rubicz R, Peralta JM, Almeida MAA, Kent JW Jr, Dyer TD, Comuzzie AG, Göring HH, Duggirala R, Almasy L, Blangero J (2014) Evaluation of estimated genetic values and their application to genome-wide investigation of systolic blood pressure. BMC Proceedings 2014, 8(Suppl 1):S66 doi:10.1186/1753-6561-8-S1-S66. eCollection 2014. PubMed PMID: 25519398; PubMed Central PMCID: PMC4143678.
125. Almasy L, Dyer TD, Peralta JM, Goo J, Wood AR, Fuchsberger C, Almeida MA, Kent JW Jr, Fowler S, Blackwell TW, Puppala S, Kumar S, Curran JE, Lehman D, Abecasis G, Duggirala R, Blangero J, and the T2D-GENES Consortium (2014) Data for Genetic Analysis Workshop 18: Human whole genome sequence, blood pressure, and simulated phenotypes in extended pedigrees. BMC Proceedings 2014, 8(Suppl 1):S2 doi:10.1186/ 1753-6561-8-S1-S2. eCollection 2014.PubMed PMID: 25519314; PubMed Central PMCID: PMC4145406.
126. DeMenna J, Puppala S, Chittoor G, Schneider J, Kim JY, Shaibi GQ, Mandarino LJ, Duggirala R, Coletta DK (2014) Association of common genetic variants with diabetes and metabolic syndrome related traits in the Arizona Insulin Resistance (AIR) Registry: a focus on Mexican American families in the Southwest. Hum Hered. 2014;78(1):47-58.
27 doi: 10.1159/000363411. Epub 2014 Jul 8.
127. Glahn DC, Williams JT, McKay DR, Knowles EE, Sprooten E, Mathias SR, Curran JE, Kent JW Jr, Carless MA, Göring HH, Dyer TD, Woolsey MD, Winkler AM, Olvera RL, Kochunov P, Fox PT, Duggirala R, Almasy L, Blangero J (2014) Discovering Schizophrenia Endophenotypes in Randomly Ascertained pedigrees. Biol Psychiatry. 2014 Jul 21. pii: S0006-3223(14)00521-6. doi: 10.1016/j.biopsych.2014.06.027. [Epub ahead of print]. PubMed PMID: 25168609; PubMed Central PMCID: PMC4261014.
128. Dager AD, McKay DR, Kent JW Jr, Curran JE, Knowles E, Sprooten E, Göring HH, Dyer TD, Pearlson GD, Olvera RL, Fox PT, Lovallo WR, Duggirala R, Almasy L, Blangero J, Glahn DC (2014) Shared Genetic Factors Influence Amygdala Volumes and Risk for Alcoholism. Neuropsychopharmacology. 2014 Jul 31. doi: 10.1038/npp.2014.187. [Epub ahead of print].
129. Mamtani M, Kulkarni H, Dyer TD, Almasy L, Mahaney MC, Duggirala R, Comuzzie AG, Samollow PB, Blangero J, Curran JE (2014) Increased waist circumference is independently associated with hypothyroidism in Mexican Americans: replicative evidence from two large, population-based studies. BMC Endocr Disord. 2014 Jun 10;14:46. doi: 10.1186/1472-6823-14-46.
130. Majithia AR, Flannick J, Shahinian P, Guo M, (Consortium, Multi-author paper….. Duggirala R, …..Teslovich TM, Torres J, Trubetskoy V, Willems SM, Williams AL, Wilson JG, Wiltshire S, Won S, Wood AR, Xu W, Teo YY, Yoon J, Lee JY, Zawistowski M, Zeggini E, Zhang W, Zöllner S (2014) Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes. Proc Natl Acad Sci U S A. 2014 Aug 25. pii: 201410428. [Epub ahead of print]
131. Ng MC, Shriner D, Chen BH, Li J, Chen WM, (Consortium, Multi-author paper) …..MEta-analysis of type 2 DIabetes in African Americans Consortium [includes Duggirala R and others as collaborators] (2014) Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes. PLoS Genet. 2014 Aug;10(8):e1004517. doi: 10.1371/journal.pgen. 1004517. eCollection 2014 Aug.
132. Knowles EE, McKay DR, Kent JW Jr, Sprooten E, Carless MA, Curran JE, de Almeida MA, Dyer TD, Göring HH, Olvera RL, Duggirala R, Fox PT, Almasy L, Blangero J, Glahn DC (2014) Pleiotropic locus for emotion recognition and amygdala volume identified using univariate and bivariate linkage. Am J Psychiatry. 2014 Oct 10. doi: 10.1176/appi.ajp.2014.14030311. [Epub ahead of print]
133. Wood AR, Tuke MA, Nalls M, Hernandez D, Gibbs JR, Lin H, Xu CS, Li Q, Shen J, Jun G, Almeida M, Tanaka T, Perry JR, Gaulton K, Rivas M, Pearson R, Curran JE, Johnson MP, Göring HH, Duggirala R, Blangero J, McCarthy MI, Bandinelli S, Murray A, Weedon MN, Singleton A, Melzer D, Ferrucci L, Frayling TM (2014) Whole-genome sequencing to understand the genetic architecture of common gene expression and biomarker phenotypes. Hum Mol Genet. 2014 Nov 6. pii: ddu560. [Epub ahead of print]
134. Farook VS, Reddivari L, Chittoor G, Puppala S, Arya R, Fowler SP, Mohan B, Hunt KJ,
28 Curran JE, Comuzzie AG, Lehman DM, Jenkinson CP, Lynch JL, DeFronzo RA, Blangero J, Hale DE, Duggirala R, Vanamala J (2014) Metabolites as novel biomarkers for childhood obesity-related traits in Mexican American children. Pediatr Obes. 2014 Nov 18. doi: 10.1111/ijpo.270. [Epub ahead of print]. PubMed PMID: 25405847; PubMed Central PMCID: PMC4436034.
135. Hibar DP, Stein JL, Renteria ME, Arias-Vasquez A, (Consortium, Multi-author paper) .....Duggirala R, …..The Alzheimer’s Disease Neuroimaging Initiative; The CHARGE Consortium; EPIGEN; IMAGEN; SYS, Martin NG, Wright MJ, Schumann G, Franke B, Thompson PM, Medland SE (2015) Common genetic variants influence human subcortical brain structures. Nature. 2015 Apr 9; 520(7546):224-9. doi: 10.1038/nature 14101. Epub 2015 Jan 21. PubMed PMID:25607358; PubMed Central PMCID: PMC4393366.
136. Mahajan A, Sim X, Ng HJ, Manning A, (Consortium, Multi-author paper)….. Duggirala R, …..T2D-GENES consortium and GoT2D consortium (2015) Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus. PLoS Genet. 2015 Jan 27;11(1):e1004876. doi:10.1371/journal.pgen.1004876. eCollection 2015 Jan. PubMed PMID: 25625282; PubMed Central PMCID: PMC4307976.
137. Kochunov P, Jahanshad N, Marcus D, Winkler A, Sprooten E, Nichols TE, Wright SN, Hong LE, Patel B, Behrens T, Jbabdi S, Andersson J, Lenglet C, Yacoub E, Moeller S, Auerbach E, Ugurbil K, Sotiropoulos SN, Brouwer RM, Landman B, Lemaitre H, den Braber A, Zwiers MP, Ritchie S, van Hulzen K, Almasy L, Curran J, deZubicaray GI, Duggirala R, Fox P, Martin NG, McMahon KL, Mitchell B, Olvera RL, Peterson C, Starr J, Sussmann J, Wardlaw J, Wright M, Boomsma DI, Kahn R, de Geus EJ, Williamson DE, Hariri A, van 't Ent D, Bastin ME, McIntosh A, Deary IJ, Hulshoff Pol HE, Blangero J, Thompson PM, Glahn DC, Van Essen DC (2015) Heritability of fractional anisotropy in human white matter: a comparison of Human Connectome Project and ENIGMA-DTI data. Neuroimage. 2015 May 1;111:300-11. doi: 10.1016/j.neuroimage. 2015.02.050. Epub 2015 Mar 4. PubMed PMID: 25747917; PubMed Central PMCID: PMC4387079.
138. Rubicz R, Yolken R, Drigalenko E, Carless MA, Dyer TD, Kent J Jr, Curran JE, Johnson MP, Cole SA, Fowler SP, Arya R, Puppala S, Almasy L, Moses EK, Kraig E, Duggirala R, Blangero J, Leach CT, Göring HH (2015) Genome-wide genetic investigation of serological measures of common infections. Eur J Hum Genet. 2015 Mar 11. doi: 10.1038/ejhg.2015.24. [Epub ahead of print] PubMed PMID: 25758998.
139. Spieker EA, Kochunov P, Rowland LM, Sprooten E, Winkler AM, Olvera RL, Almasy L, Duggirala R, Fox PT, Blangero J, Glahn DC, Curran JE (2015) Shared genetic variance between obesity and white matter integrity in Mexican Americans. Front Genet. 2015 Feb 13;6:26. doi: 10.3389/fgene.2015.00026. eCollection 2015. PubMed PMID: 25763009; PubMed Central PMCID: PMC4327744.
140. Williams AL, Genovese G, Dyer T, Altemose N, Truax K, Jun G, Patterson N, Myers SR, Curran JE, Duggirala R, Blangero J, Reich D, Przeworski M; T2D-GENES Consortium (2015) Non-crossover gene conversions show strong GC bias and unexpected
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141. Winnier DA, Fourcaudot M, Norton L, Abdul-Ghani MA, Hu SL, Farook VS, Coletta, DK, Kumar S, Puppala S, Chittoor G, Dyer TD, Arya R, Carless M, Lehman DM, Curran JE, Cromack DT, Tripathy D, Blangero J, Duggirala R, Göring HH, DeFronzo RA, Jenkinson CP (2015) Transcriptomic identification of ADH1B as a novel candidate gene for obesity and insulin resistance in human adipose tissue in Mexican Americans from the Veterans Administration Genetic Epidemiology Study (VAGES). PLoS One. 2015 Apr 1;10(4):e0119941. doi: 10.1371/journal.pone.0119941. eCollection 2015. PubMed PMID: 25830378; PubMed Central PMCID: PMC4382323.
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150. Kulkarni H, Mamtani M, Peralta J, Almeida M, Dyer TD, Goring HH, Johnson MP, Duggirala R, Mahaney MC, Olvera RL, Almasy L, Glahn DC, Williams-Blangero S, Curran JE, Blangero J (2016) Soluble Forms of Intercellular and Vascular Cell Adhesion Molecules Independently Predict Progression to Type 2 Diabetes in Mexican American Families. PLoS One. 2016 Mar 23;11(3):e0151177. doi:10.1371/journal.pone.0151177. eCollection 2016. PubMed PMID: 27007680; PubMed Central PMCID: PMC4805238.
151. Horikoshi M, Pasquali L, Wiltshire S, Huyghe JR, Mahajan A, Asimit JL, Ferreira T, Locke AE, Robertson NR, Wang X, Sim X, Fujita H, Hara K, Young R, Zhang W, Choi S, Chen H, Kaur I, Takeuchi F, Fontanillas P, Thuillier D, Yengo L, Below JE, Tam CH, Wu Y, Abecasis G, Altshuler D, Bell GI, Blangero J, Burtt NP, Duggirala R, Florez JC, Hanis CL, Seielstad M, Atzmon G, Chan JC, Ma RC, Froguel P, Wilson JG, Bharadwaj D, Dupuis J, Meigs JB, Cho YS, Park T, Kooner JS, Chambers JC, Saleheen D, Kadowaki T, Tai ES, Mohlke KL, Cox NJ, Ferrer J, Zeggini E, Kato N, Teo YY, Boehnke M, McCarthy MI, Morris AP; T2D-GENES Consortium (2016) Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms. Hum Mol Genet. 2016 Feb 23.pii: ddw048. [Epub ahead of print] PubMed PMID: 26911676.
152. Kim JY, DeMenna JT, Puppala S, Chittoor G, Schneider J, Duggirala R, Mandarino LJ, Shaibi GQ, Coletta DK (2016) Physical activity and FTO genotype by physical activity interactive influences on obesity. BMC Genet. 2016 Feb 24;17(1):47. doi: 10.1186/s 12863-016-0357-6. PubMed PMID: 26908368; PubMed Central PMCID: PMC4765034.
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154. Mamtani M, Kulkarni H, Dyer TD, Göring HH, Neary JL, Cole SA, Kent JW, Kumar S, Glahn DC, Mahaney MC, Comuzzie AG, Almasy L, Curran JE, Duggirala R, Blangero J, Carless MA (2016) Genome- and epigenome-wide association study of hypertriglyceridemic waist in Mexican American families. Clin Epigenetics. 2016 Jan 20;8:6. doi: 10.1186/s13148-016-0173-x. eCollection 2016. PubMed PMID: 26798409; PubMed Central PMCID: PMC4721061.
155. Kim YJ, Lee J, Kim BJ; T2D-Genes Consortium, Park T (2016) A new strategy for enhancing imputation quality of rare variants from next-generation sequencing data via combining SNP and exome chip data. BMC Genomics. 2015 Dec 29;16(1):1109. doi: 10.1186/s12864-015-2192-y. PubMed PMID: 26715385; PubMed Central PMCID: PMC4696174 (Dugggirala R, Collaborating Author).
156. Jenkinson CP, Göring HH, Arya R, Blangero J, Duggirala R, DeFronzo RA (2016) Transcriptomics in type 2 diabetes: Bridging the gap between genotype and phenotype. Genom Data. 2015 Dec 17;8:25-36. doi: 10.1016/j.gdata.2015.12.001. eCollection 2016.
157. Hanson RL, Leti F, Tsinajinnie D, Kobes S, Puppala S, Curran JE, Almasy L, Lehman DM, Blangero J, Duggirala R, DiStefano JK (2016) The Arg59Trp variant in ANGPTL8 (betatrophin) is associated with total and HDL-cholesterol in American Indians and Mexican Americans and differentially affects cleavage of ANGPTL3. Mol Genet Metab. 2016 June;118 (2):128-37. PubMed PMID: 27117576; PubMed Central PMCID: PMC4880492.
158. Thameem F, Puppala S, Farook VS, Kasinath BS, Blangero J, Duggirala R, Abboud HE (2016) Genetic variants in Toll-Like Receptor 4 (TLR4) gene and their association analysis with estimated Glomerular Filtration Rate (eGFR) in Mexican American Families. Cardiorenal Med. 2016 Aug;6(4):301-6. PubMed PMID: 27648011; PubMed Central PMCID: PMC5020380.
159. Hodgson K, Almasy L, Knowles EE, Kent JW, Curran JE, Dyer TD, Göring HH, Olvera RL, Fox PT, Pearlson GD, Krystal JH, Duggirala R, Blangero J, Glahn DC (2016) Genome-wide significant loci for addiction and anxiety. Eur Psychiatry. 2016 Aug;36:47- 54. doi:10.1016/j.eurpsy.2016.03.004. PubMed PMID: 27318301.
160. Nicholson AM, Finch NA, Almeida M, Perkerson RB, van Blitterswijk M, Wojtas A, Cenik B, Rotondo S, Inskeep V, Almasy L, Dyer T, Peralta J, Jun G, Wood AR, Frayling TM, Fuchsberger C, Fowler S, Teslovich TM, Manning AK, Kumar S, Curran J, Lehman D, Abecasis G, Duggirala R, Pottier C, Zahir HA, Crook JE, Karydas A, Mitic L, Sun Y, Dickson DW, Bu G, Herz J, Yu G, Miller BL, Ferguson S, Petersen RC, Graff-Radford N,
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161. Fuchsberger C, Flannick J, Teslovich TM, Mahajan A, (Consortium, Multi-author paper)…. Blangero J, Duggirala R, Tai ES, McVean G, Hanis CL, Wilson JG, Seielstad M, Frayling TM, Meigs JB, Cox NJ, Sladek R, Lander ES, Gabriel S, Burtt NP, Mohlke KL, Meitinger T, Groop L, Abecasis G, Florez JC, Scott LJ, Morris AP, Kang HM, Boehnke M, Altshuler D, McCarthy MI (2016). The genetic architecture of type 2 diabetes. Nature. 2016 Aug 4;536(7614):41-7. PubMed PMID: 27398621; PubMed Central PMCID: PMC5034897.
162. Lek M, Karczewski KJ, Minikel EV, Samocha KE, (Consortium, Multi-author paper)…. Exome Aggregation Consortium (2016) Analysis of protein-coding genetic variation in 60,706 humans. Nature. 2016 Aug 18;536(7616):285-91. doi: 10.1038/nature19057. PubMed PMID: 27535533; PubMed Central PMCID: PMC5018207. (Dugggirala R, Collaborating Author).
163. Parsa A, Kanetsky PA, Xiao R, Gupta J, (Consortium, Multi-author paper)…. FIND Consortium., Groop PH, Forsblom C, Freedman BI, Lipkowitz M, Fox CS, Winkler CA, Feldman HI; and the Chronic Renal Insufficiency Cohort (CRIC) Study Investigators (2016) Genome-Wide Association of CKD Progression: The Chronic Renal Insufficiency Cohort Study. J Am Soc Nephrol. 2016 Oct 11. pii: ASN.2015101152. [Epub ahead of print] PubMed PMID: 27729571. (Dugggirala R, Collaborating Author).
164. Hodgson K, Poldrack RA, Curran JE, Knowles EE, Mathias S, Göring HH, Yao N, Olvera RL, Fox PT, Almasy L, Duggirala R, Barch DM, Blangero J, Glahn DC (2016) Shared Genetic Factors Influence Head Motion During MRI and Body Mass Index. Cereb Cortex. 2016 Oct 15. [Epub ahead of print] PubMed PMID: 27744290.
165. Garibay-Nieto N, Queipo-Garcia G, Alvarez-Huerta F, Bustos-Esquivel M, Villanueva- Ortega E, Ramirez F, Leon M, Laresgoiti-Servitje E, Duggirala R, Macias T, Cuevas S, Jalife A, Fonseca-Sanchez M, Serratos F, Lopez-Alvarenga JC (2016) Conjugated Linoleic Acid and Metformin on Insulin Sensitivity in obese children: Randomized Clinical Trial. J Clin Endocrinol Metab. 2016 Oct 25:jc20162701. [Epub ahead of print] PubMed PMID: 27778642.
166. Adams HH, Hibar DP, Chouraki V, Stein JL, (Consortium, Multi-author paper)…. Duggirala R, ….. Medland SE, Ikram MA, Thompson PM (2016) Novel genetic loci underlying human intracranial volume identified through genome-wide association. Nat Neurosci. 2016 Dec;19(12):1569-1582. doi: 10.1038/nn.4398. PubMed PMID: 27694991; PubMed Central PMCID: PMC5227112.
167. Kulkarni H, Mamtani M, Peralta JM, Diego V, Dyer TD, Goring H, Almasy L, Mahaney MC, Williams-Blangero S, Duggirala R, Curran JE, Blangero J (2016) Lack of Association between SLC30A8 Variants and Type 2 Diabetes in Mexican American Families. J Diabetes Res. 2016;2016:6463214. PubMed PMID: 27896278; PubMed Central PMCID: PMC5118530.
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169. Almeida M, Blondell L, Peralta JM, Kent JW Jr, Jun G, Teslovich TM, Fuchsberger C, Wood AR, Manning AK, Frayling TM, Cingolani PE, Sladek R, Dyer TD, Abecasis G, Duggirala R, Blangero J (2016) Independent test assessment using the extreme value distribution theory. BMC Proc. 2016 Oct 18;10(Suppl 7):245-249. PubMed PMID: 27980644; PubMed Central PMCID: PMC5133519.
170. Hibar DP, Adams HH, Jahanshad N, Chauhan G, (Consortium, Multi-author paper)…. Duggirala R, …..Medland SE, Seshadri S, Thompson PM, Ikram MA (2017) Novel genetic loci associated with hippocampal volume. Nat Commun. 2017 Jan 18;8:13624. doi:10.1038/ncomms13624. PubMed PMID: 28098162; PubMed Central PMCID: PMC5253632.
171. Hodgson K, Almasy L, Knowles EE, Kent JW Jr, Curran JE, Dyer TD, Göring HH, Olvera RL, Woolsey MD, Duggirala R, Fox PT, Blangero J, Glahn DC (2017) The genetic basis of the comorbidity between cannabis use and major depression. Addiction. 2017 Jan;112(1):113-123. doi: 10.1111/add.13558. PubMed PMID: 27517884; PubMed Central PMCID:PMC5148647.
172. Perez-Navarro LM, Restrepo BI, Fuentes-Dominguez FJ, Duggirala R, Morales-Romero J, Lopez-Alvarenga JC, Comas I, Zenteno-Cuevas R (2017). The effect size of type 2 diabetes mellitus on tuberculosis drug resistance and adverse treatment outcomes. Tuberculosis 103:83-91 doi:10.1016/j.tube.2017.01.006. Epub 2017 Jan 24. PubMed PMID: 28237037.
173. Knowles EEM, Meikle PJ, Huynh K, Goring HHH, Olvera RL, Mathias SR, Duggirala R, Almasy L, Blangero J, Curran JE, Glahn DC (2017) Serum phosphatidylinositol as a biomarker for bipolar disorder liability. Bipolar Disorders. 2017 Mar;19(2):107-115. doi: 10.1111/bdi.12468. Epub 2017 Feb 23. PubMed PMID: 28230325.
174. Manning A, Highland HM, Gasser J, Sim X, Tukiainen T, Fontanillas P, Grarup N, …(Consortium, Multi-author paper including Duggirala R)…Boehnke M, Altshuler D, McCarthy MI, Gloyn AL, Lindgren CM. A low-frequency inactivating Akt2 variant enriched in the Finnish population is associated with fasting insulin levels and type 2 diabetes risk. Diabetes. 2017 Mar 24. pii: db161329. doi: 10.2337/db16-1329. [Epub ahead of print] PubMed PMID: 28341696.
175. Knowles EE, Huynh K, Meikle PJ, Göring HH, Olvera RL, Mathias SR, Duggirala R, Almasy L, Blangero J, Curran JE, Glahn DC (2017) The lipidome in major depressive disorder: Shared genetic influence for ether-phosphatidylcholines, a plasma-based phenotype related to inflammation, and disease risk. Eur Psychiatry. 2017 Feb 21;43:44-
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176. Hodgson K, Carless MA, Kulkarni H, Curran JE, Sprooten E, Knowles EE, Mathias S, Göring HHH, Yao N, Olvera RL, Fox PT, Almasy L, Duggirala R, Blangero J, Glahn DC (2017) Epigenetic Age Acceleration Assessed with Human White-Matter Images. J Neurosci. 2017 May 3;37(18):4735-4743. doi: 10.1523/JNEUROSCI.0177-17.2017. Epub 2017 Apr 6. PubMed PMID: 28385874; PubMed Central PMCID: PMC5426566.
177. Romero-Ibarguengoitia ME, Herrera-Rosas A, Domínguez-Mota AA, Camas-Benitez JT, Serratos-Canales MF, León-Hernández M, González-Chávez A, López-Ortiz E, Mummidi S, Duggirala R, López-Alvarenga JC (2017) Nonalcoholic fatty liver disease can be predicted by retinal vascular changes in patients with obesity without hypertension or diabetes. Eur J Gastroenterol Hepatol. 2017 May 3. doi: 10.1097/ MEG.0000000000000900. [Epub ahead of print] PubMed PMID: 28471828.
178. Farook VS, Reddivari L, Mummidi S, Puppala S, Arya R, Lopez-Alvarenga JC, Fowler SP, Chittoor G, Resendez RG, Kumar BM, Comuzzie AG, Curran JE, Lehman DM, Jenkinson CP, Lynch JL, DeFronzo RA, Blangero J, Hale DE, Duggirala R, Vanamala JKP (2017) Genetics of serum carotenoid levels and their correlation with obesity-related traits in Mexican American children. Am J Clin Nutr. 2017 May 17. pii: ajcn144006. doi: 10.3945/ajcn.116.144006. [Epub ahead of print] PubMed PMID: 28515064.
179. Kulkarni H, Mamtani M, Wong G, Weir JM, Barlow CK, Dyer TD, Almasy L, Mahaney MC, Comuzzie AG, Duggirala R, Meikle PJ, Blangero J, Curran JE (2017) Genetic correlation of the plasma lipidome with type 2 diabetes, prediabetes and insulin resistance in Mexican American families. BMC Genet. 2017 May 19;18(1):48. doi: 10.1186/s12863-017-0515-5. PubMed PMID: 28525987; PubMed Central PMCID: PMC5438505.
180. Reding-Bernal A, Sánchez-Pedraza V, Moreno-Macías H, Sobrino-Cossio S, Tejero- Barrera ME, Burguete-García AI, León-Hernández M, Serratos-Canales MF, Duggirala R, López-Alvarenga JC (2017) Heritability and genetic correlation between GERD symptoms severity, metabolic syndrome, and inflammation markers in families living in Mexico City. PLoS One. 2017 Jun 5;12(6):e0178815. doi: 10.1371/journal.pone.0178815. eCollection 2017. PubMed PMID: 28582452.
181. Ramstetter MD, Dyer T, Lehman DM, Curran JE, Duggirala R, Blangero J, Mezey JG, Williams AL. Benchmarking Relatedness Inference Methods with Genome-Wide Data from Thousands of Relatives. Genetics. 2017 Jul 24. pii: genetics.1122.2017. doi: 10.1534/genetics.117.1122. [Epub ahead of print] PubMed PMID: 28739658.
182. Mercader JM, Liao RG, Bell AD, Dymek Z, Estrada K, Tukiainen T, Huerta-Chagoya A, Moreno-Macías H, Jablonski KA, Hanson RL, Walford GA, Moran I, Chen L, Agarwala V, Ordoñez-Sánchez ML, Rodríguez-Guillen R, Rodríguez-Torres M, Segura-Kato Y, García-Ortiz H, Centeno-Cruz F, Barajas-Olmos F, Caulkins L, Puppala S, Fontanillas P, Williams A, Bonàs-Guarch S, Hartl C, Ripke S; Diabetes Prevention Program Research Group, Tooley K, Lane J, Zerrweck C, Martínez-Hernández A, Córdova EJ, Mendoza- Caamal E, Contreras-Cubas C, González-Villalpando ME, Cruz-Bautista I, Muñoz- Hernández L, Gómez-Velasco D, Alvirde U, Henderson BE, Wilkens LR, Le Marchand L,
35 Arellano-Campos O, Riba L,Harden M, Platform BG, Gabriel S; T2D-GENES Consortium, Abboud HE, Cortes ML, Revilla-Monsalve C, Islas-Andrade S, Soberon X, Curran JE, Jenkinson CP, DeFronzo RA, Lehman DM, Hanis CL, Bell GI, Boehnke M, Blangero J, Duggirala R, Saxena R, MacArthur D, Ferrer J, McCarroll SA, Torrents D, Knowler WC, Baier LJ, Burtt N, González-Villalpando C, Haiman CA, Aguilar-Salinas CA, Tusié-Luna T, Flannick J, Jacobs SBR, Orozco L, Altshuler D, Florez JC. A Loss-Of- Function Splice Acceptor Variant in IGF2 is Protective for Type 2 Diabetes. Diabetes. 2017 Aug 24. pii: db170187. doi: 10.2337/db17-0187. [Epub ahead of print] PubMed PMID: 28838971.
183. Hodgson K, Poldrack RA, Curran JE, Knowles EE, Mathias S, Göring HHH, Yao N, Olvera RL, Fox PT, Almasy L, Duggirala R, Barch DM, Blangero J, Glahn DC. Shared Genetic Factors Influence Head Motion During MRI and Body Mass Index. Cereb Cortex. 2017 Dec 1;27(12):5539-5546. doi: 10.1093/cercor/bhw321. PubMed PMID: 27744290; PubMed Central PMCID: PMC6075600.
184. Flannick J, Fuchsberger C, Mahajan A, Teslovich TM, (Consortium, Multi-author paper)… Blangero J, Duggirala R, Tai ES, McVean G, Hanis CL, Wilson JG, Seielstad M, Frayling TM, Meigs JB, Cox NJ, Sladek R, Lander ES, Gabriel S, Mohlke KL, Meitinger T, Groop L, Abecasis G, Scott LJ, Morris AP, Kang HM, Altshuler D, Burtt NP, Florez JC, Boehnke M, McCarthy MI. Sequence data and association statistics from 12,940 type 2 diabetes cases and controls. Sci Data. 2017 Dec 19;4:170179. doi: 10.1038/sdata.2017.179. Erratum in: Sci Data. 2018 Jan 23;5:180002. PubMed PMID: 29257133; PubMed Central PMCID: PMC5735917.
185. Alegría-Díaz A, Valdez-Ortiz R, Murguía-Romero M, Jiménez-Flores R, Villalobos-Molina R, Mummidi S, Duggirala R, López-Alvarenga JC, Pérez-Navarro M. Clinical Significance of Serum Uric Acid Levels in Mexican Young Adults. Contrib Nephrol. 2018;192:125-134. doi: 10.1159/000484287. Epub 2018 Jan 23. PubMed PMID: 29393152.
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187. Arya R, Escalante A, Farook VS, Restrepo JF, Battafarano DF, Almeida M, Kos MZ, Fourcaudot MJ, Mummidi S, Kumar S, Curran JE, Jenkinson CP, Blangero J, Duggirala R, Del Rincon I. Data on genetic associations of carotid atherosclerosis markers in Mexican American and European American rheumatoid arthritis subjects. Data Brief.
36 2018 Feb 8;17:820-829. doi: 10.1016/j.dib.2018.02.006. eCollection 2018 Apr. PubMed PMID: 29527544; PubMed Central PMCID: PMC5842364.
188. Romero-Ibarguengoitia ME, Vadillo-Ortega F, Caballero AE, Ibarra-González I, Herrera- Rosas A, Serratos-Canales MF, León-Hernández M, González-Chávez A, Mummidi S, Duggirala R, López-Alvarenga JC. Family history and obesity in youth, their effect on acylcarnitine/aminoacids metabolomics and non-alcoholic fatty liver disease (NAFLD). Structural equation modeling approach. PLoS One. 2018 Feb 21;13(2):e0193138. doi: 10.1371/journal.pone.0193138. eCollection 2018. Erratum in: PLoS One. 2018 May 24;13(5):e0198379. PubMed PMID: 29466466; PubMed Central PMCID: PMC5821462.
189. Arya R, Farook VS, Fowler SP, Puppala S, Chittoor G, Resendez RG, Mummidi S, Vanamala J, Almasy L, Curran JE, Comuzzie AG, Lehman DM, Jenkinson CP, Lynch JL, DeFronzo RA, Blangero J, Hale DE, Duggirala R, Diego VP. Genetic and environmental (physical fitness and sedentary activity) interaction effects on cardiometabolic risk factors in Mexican American children and adolescents. Genet Epidemiol. 2018 Jun;42(4):378-393. doi: 10.1002/gepi.22114. Epub 2018 Feb 20. PubMed PMID: 29460292; PubMed Central PMCID: PMC5980678.
190. Zekavat SM, Ruotsalainen S, Handsaker RE, Alver M, Bloom J, Poterba T, Seed C, Ernst J, Chaffin M, Engreitz J, Peloso GM, Manichaikul A, Yang C, Ryan KA, Fu M, Johnson WC, Tsai M, Budoff M, Vasan RS, Cupples LA, Rotter JI, Rich SS, Post W, Mitchell BD, Correa A, Metspalu A, Wilson JG, Salomaa V, Kellis M, Daly MJ, Neale BM, McCarroll S, Surakka I, Esko T, Ganna A, Ripatti S, Kathiresan S, Natarajan P; NHLBI TOPMed Lipids Working Group. Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries. Nat Commun. 2018 Jul 4;9(1):2606. doi: 10.1038/s41467-018-04668-w. Erratum in: Nat Commun. 2018 Aug 23;9(1):3493. PubMed PMID: 29973585; PubMed Central PMCID: PMC6031652. Duggirala R is a collaborator/author.
191. Ramstetter MD, Shenoy SA, Dyer TD, Lehman DM, Curran JE, Duggirala R, Blangero J, Mezey JG, Williams AL. Inferring Identical-by-Descent Sharing of Sample Ancestors Promotes High-Resolution Relative Detection. Am J Hum Genet. 2018 Jul 5;103(1):30-44. doi: 10.1016/j.ajhg.2018.05.008. Epub 2018 Jun 21. PubMed PMID: 29937093; PubMed Central PMCID: PMC6035284.
192. Natarajan P, Peloso GM, Zekavat SM, Montasser M, Ganna A, Chaffin M, Khera AV, Zhou W, Bloom JM, Engreitz JM, Ernst J, O'Connell JR, Ruotsalainen SE, Alver M, Manichaikul A, Johnson WC, Perry JA, Poterba T, Seed C, Surakka IL, Esko T, Ripatti S, Salomaa V, Correa A, Vasan RS, Kellis M, Neale BM, Lander ES, Abecasis G, Mitchell B, Rich SS, Wilson JG, Cupples LA, Rotter JI, Willer CJ, Kathiresan S; NHLBI TOPMed Lipids Working Group. Deep-coverage whole genome sequences and blood lipids among 16,324 individuals. Nat Commun. 2018 Aug 23;9(1):3391. doi: 10.1038/s41467-018-05747-8. PubMed PMID: 30140000; PubMed Central PMCID: PMC6107638. Duggirala R is a collaborator/author.
193. Knowles EEM, Mathias SR, Mollon J, Rodrigue A, Koenis MMG, Dyer TD, Goring HHH, Curran JE, Olvera RL, Duggirala R, Almasy L, Blangero J, Glahn DC. A QTL on chromosome 3q23 influences processing speed in humans. Genes Brain Behav. 2018
37 [Epub ahead of print]. 2019;29(1):106-118. PubMed PMID: 30379395; PubMed Central PMCID: PMC6458095.
194. Knowles EEM, Curran JE, Meikle PJ, Huynh K, Mathias SR, Göring HHH, VandeBerg JL, Mahaney MC, Jalbrzikowski M, Mosior MK, Michael LF, Olvera RL, Duggirala R, Almasy L, Glahn DC, Blangero J. Disentangling the genetic overlap between cholesterol and suicide risk. Neuropsychopharmacology. 2018 Dec;43(13):2556-2563. PubMed PMID: 30082891; PubMed Central PMCID: PMC6224547.
195. Alexander-Bloch AF, Mathias SR, Fox PT, Olvera RL, Göring HHH, Duggirala R, Curran JE, Blangero J, Glahn DC. Human Cortical Thickness Organized into Genetically-determined Communities across Spatial Resolutions. Cereb Cortex. 2019 Jan 1;29(1):106-118. PubMed PMID: 29190330; PubMed Central PMCID: PMC6676978.
196. Flannick JA, Mercader JMM, Fuchsberger C, Udler MS, Mahajan A, Wessel J, (Consortium, Multi-author paper)…..Duggirala…..DiscovEHR Collaboration, CHARGE, LuCamp, ProDiGY, GoT2D, ESP, SIGMA-T2D, T2D-GENES, AMP-T2D- GENES, Altshuler D, Burtt NP, Scott L, Morris A, Florez J, McCarthy M, Boehnke M. Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls. Nature. 2019; 570 (7759):71-76. PubMed PMID: 31118516; PubMed Central PMCID: PMC6699738.
197. Guan M, Keaton JM, Dimitrov L, Hicks PJ, Xu J, Palmer ND, Ma L, Das SK, Chen YI, Coresh J, Fornage M, Franceschini N, Kramer H, Langefeld CD, Mychaleckyj JC, Parekh RS, Post WS, Rasmussen-Torvik LJ, Rich SS, Rotter JI, Sedor JR, Thornley- Brown D, Tin A, Wilson JG, Freedman BI, Bowden DW, Ng MCY; FIND Consortium. Genome-wide association study identifies novel loci for type 2 diabetes-attributed end- stage kidney disease in African Americans. Hum Genomics. 2019 May 15;13(1):21. PubMed PMID: 31092297; PubMed Central PMCID: PMC6521376. Duggirala R is a collaborator/author.
198. Knowles EEM, Curran JE, Göring HHH, Mathias SR, Mollon J, Rodrigue A, Olvera RL, Leandro A, Duggirala R, Almasy L, Blangero J, Glahn DC. Family-based analyses reveal novel genetic overlap between cytokine interleukin-8 and risk for suicide attempt. Brain Behav Immun. 2019; 80:292-299. Epub 2019 Apr 3. PubMed PMID: 30953777.
199. Blackburn NB, Michael LF, Meikle PJ, Peralta JM, Mosior M, McAhren S, Bui HH, Bellinger MA, Giles C, Kumar S, Leandro AC, Almeida M, M. Weir JM, Mahaney MC, Dyer TD, Almasy L, VandeBerg JL, Williams-Blangero S, Glahn DC, Duggirala R, Kowala M, Blangero J, Curran JE. Rare DEGS1 variant significantly alters de novo ceramide synthesis pathway. J Lipid Res. 2019; 60(9): 1630-1639. PubMed PMID: 31227640; PubMed Central PMCID: PMC6718439.
200. Rodrigue AL, Knowles EE, Mollon J, Mathias SR, Koenis MM, Peralta JM, Leandro AC, Fox PT, Sprooten E, Kochunov P, Olvera RL, Duggirala R, Almasy L, Curran JE, Blangero J, Glahn DC. Evidence for genetic correlation between human cerebral white matter microstructure and inflammation. Hum Brain Mapp. 2019; 40(14):4180-4191. Epub 2019 Jun 11. PubMed PMID: 31187567; PubMed Central PMCID: PMC6707845.
38
201. Kachroo P, Hecker J, Chawes BL, Ahluwalia TS, Cho MH, Qiao D, Kelly RS, Chu SH, Virkud YV, Huang M, Barnes KC, Burchard EG, Eng C, Hu D, Celedón JC, Daya M, Levin AM, Gui H, Williams LK, Forno E, Mak ACY, Avila L, Soto-Quiros ME, Cloutier MM, Acosta-Pérez E, Canino G, Bønnelykke K, Bisgaard H, Raby BA, Lange C, Weiss ST, Lasky-Su JA; National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Consortium. Whole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children with Asthma. Chest. 2019; 156(6):1068-1079. Epub 2019 Sep 23. PubMed PMID: 31557467; PubMed Central PMCID: PMC6904857. Duggirala R is a collaborator/author.
202. Caballero M, Seidman DN, Qiao Y, Sannerud J, Dyer TD, Lehman DM, Curran JE, Duggirala R, Blangero J, Carmi S, Williams AL. Crossover interference and sex-specific genetic maps shape identical by descent sharing in close relatives. PLoS Genet. 2019; 15(12): e1007979. doi: 10.1371/journal.pgen.1007979. eCollection 2019 Dec. PubMed PMID: 31860654; PubMed Central PMCID: PMC6944377.
203. Mollon J, Curran JE, Mathias SR, Knowles EEM, Carlisle P, Fox PT, Olvera RL, Göring HHH, Rodrigue A, Almasy L, Duggirala R, Blangero J, Glahn DC. Neurocognitive Impairment in Type 2 Diabetes: Evidence for Shared Genetic Etiology. Diabetologia; 2020 Feb 4; doi: 0.1007/s00125-020-05101-y. [Epub ahead of print] PubMed PMID: 32016567.
204. Kessler MD, Loesch DP, Perry JA, Heard-Costa NL, Taliun D, Cade BE, Wang H, Daya M, Ziniti J, Datta S, Celedón JC, Soto-Quiros ME, Avila L, Weiss ST, Barnes K, Redline SS, Vasan RS, Johnson AD, Mathias RA, Hernandez R, Wilson JG, Nickerson DA, Abecasis G, Browning SR, Zöllner S, O'Connell JR, Mitchell BD; National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Consortium; TOPMed Population Genetics Working Group, O'Connor TD (Duggirala R is a collaborating author). Denovo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population. Proc Natl Acad Sci U S A. 2020 Feb 4;117(5):2560-2569. doi: 10.1073/pnas.1902766117. Epub 2020 Jan 21. PubMed PMID: 31964835; PubMed Central PMCID: PMC7007577.
205. Mathias SR, Knowles EEM, Mollon J, Rodrigue A, Koenis MMC, Alexander-Bloch AF, Winkler AM, Olvera RL, Duggirala R, Göring HHH, Curran JE, Fox PT, Almasy L, Blangero J, Glahn DC. Minimal Relationship between Local Gyrification and General Cognitive Ability in Humans. Cereb Cortex. 2020 Feb 9; pii: bhz319. doi: 10.1093/ cercor/ bhz319. [Epub ahead of print] PubMed PMID: 32037459.
206. Seidman DN, Shenoy SA, Kim M, Babu R, Woods IG, Dyer TD, Lehman DM, Curran JE, Duggirala R, Blangero J, Williams AL. Rapid, Phase-free Detection of Long Identity-by-Descent Segments Enables Effective Relationship Classification. Am J Hum Genet. 2020 Apr 2;106(4):453-466. doi: 10.1016/j.ajhg.2020.02.012. Epub 2020 Mar 19. PubMed PMID: 32197076.
207. Zekavat SM, Ruotsalainen S, Handsaker RE, Alver M, Bloom J, Poterba T, Seed C, Ernst J, Chaffin M, Engreitz J, Peloso GM, Manichaikul A, Yang C, Ryan KA, Fu M, Johnson WC, Tsai M, Budoff M, Vasan RS, Cupples LA, Rotter JI, Rich SS, Post W,
39 Mitchell BD, Correa A, Metspalu A, Wilson JG, Salomaa V, Kellis M, Daly MJ, Neale BM, McCarroll S, Surakka I, Esko T, Ganna A, Ripatti S, Kathiresan S, Natarajan P; NHLBI TOPMed Lipids Working Group (Duggirala R is a collaborating author). Publisher Correction: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries. Nat Commun. 2020 Apr 1;11(1):1715. doi: 10.1038/s41467-020-15236-6. PubMed PMID: 32238811; PubMed Central PMCID: PMC7113276.
208. Pérez-Navarro LM, Valdez-Ortiz R, Alegría-Díaz A, Murguía-Romero M, Jiménez-Flores R, Villalobos-Molina R, Mummidi S, Duggirala R, López-Alvarenga JC. Cardiometabolic Risk Factors Associated with Renal Function in Apparently Healthy Young Students: A Cross-Sectional Study. Rev Invest Clin. 2020;72(2):95-102.
209. Morales LD, Cromack DT, Tripathy D, Fourcaudot M, Kumar S, Curran JE, Carless M, Göring HHH, Hu SL, Lopez Alvarenga JC, Small K, Glastonbury C, Das SK, Langefeld C, Hanson R, Shueh WC, Norton L, Arya R, Mummidi M, Blangero J, DeFronzo RA, Duggirala R, Jenkinson CP. Further evidence supporting a potential role for ADH1B in obesity. (under review).
210. Lopez-Alvarenga JC, Chittoor G, Paul SF, Arya R, Puppala SR, Farook VS, Fowler SP, Resendez RG, Diaz-Badillo A, Lehman D, Mummidi S, Jenkinson CP, Lynch JL, DeFronzo RA, Blangero J, Hale DE, Duggirala R. Acanthosis nigricans as a composite marker of cardiometabolic risk and its complex association with obesity and insulin resistance in Mexican American children. (under review).
211. Mummidi S, Farook VS, Reddivari L, Hernandez-Ruiz J, Diaz-Badillo A, Fowler SP, Resendez RG, Akhtar F, Lehman DM, Jenkinson CP, Arya R, Lynch JL, DeFronzo RA, Hale DE, Blangero J, Lopez-Alvarenga JC, Duggirala R, Vanamala JK. Prediction of insulin sensitivity using serum carotenoid concentrations and Pediatric Metabolic Index in Mexican American children. (under review).
212. Diaz-Badillo A, Chittoor G, Lopez-Alvarenga JC, Arya R, Mummidi S, Puppala SR, Fowler SP, Resendez RG, Hernandez-Ruiz J, Akhtar F, Jenkinson CP, Lehman DM, Lynch JL, DeFronzo RA, Hale DE, Mitchell BD, Blangero J, Duggirala R. Genetics of bone mass related phenotypes and their correlation with cardiometabolic traits in Mexican American children. (prepared/to be submitted).
213. Farook VS, Akhtar F, Arya R, Mummidi S, Lopez-Alvarenga JC, Resendez RG, Lynch JL, Jenkinson CP, Blangero J, Camann DE, Challa S, Duggirala R. Early life exposure to environmental pollutants as assessed in deciduous teeth and cardio-metabolic risk in Mexican American Children. (prepared/to be submitted).
B.) Book Chapters:
1. Duggirala R, Crawford MH (1994) Human population structure: Use of quantitative characters. In P. K. Seth and S. Seth (eds) Human genetics: New perspectives. New Delhi: Omega Scientific Publishers, pp. 35-63.
2. Duggirala R, Bowerman WR, Crawford MH (2000) Dimensions of Type A/B behavior
40 and relationships with lipid profiles in a Mennonite population. In M. H. Crawford (ed) Different Seasons: Biological Aging among the Mennonites of the Midwestern United States. University of Kansas Publications in Anthropology, 21, Lawrence, KS, pp. 155- 164.
3. Duggirala R, Arya R, Blangero J, Crawford MH (2000) Genetic and environmental determinants of variation in phenotypes related to coronary heart disease and renal function in Mennonites. In M. H. Crawford (ed) Different Seasons: Biological Aging among the Mennonites of the Midwestern United States. University of Kansas publications in Anthropology, 21, Lawrence, KS, pp. 83-99.
4. Arya R, Puppala S, Farook VS, Chittoor G, Jenkinson CP, Blangero J, Hale DE, Duggirala R, Almasy L (2015) Mapping of susceptibility genes for obesity, type 2 diabetes, and the metabolic syndrome in human populations. In R. Duggirala, L. Almasy, S. Williams-Blangero, S.F.D. Paul, C. Kole, eds. Genome Mapping and Genomics in Human and Non-Human Primates. Springer-Verlag Berlin Heidelberg, pp. 181-245.
5. Francis Lam YW, Duggirala R, Jenkinson CP, Arya R. The Role of Pharmacogenomics in Diabetes. In Pharmacogenomics (Second Edition), Editor(s): Francis Lam YW, Scott SA, Academic Press, 2019, Pages 247-269.
C.) Books:
Duggirala R, Almasy L, Williams-Blangero S, Paul SFD, Kole C [eds] (2015) Genome Mapping and Genomics in Human and Non-Human Primates. Springer-Verlag Berlin Heidelberg.
PROFESSIONAL WORKSHOPS ATTENDED AND INVITED PRESENTATIONS
Participant, NIH (NIDDK) Sponsored Workshop: Obesity Genes, Copper Mountain, Colorado, August 4-5, 1995.
Participant, American Association of Anthropological Genetics 2nd Workshop in Anthropological Genetics (Topic: Statistical Genetic Methods in Anthropological Research), San Antonio, Texas, October 14-16, 1995.
Invited Speaker. Biological Anthropology Colloquium, Department of Anthropology, University of Kansas, “The Genetics of Diabetes Mellitus and Its Related Phenotypes,” Lawrence, KS, November 6, 1998.
Participant, American Association of Anthropological Genetics/Southwest Foundation for Biomedical Research Workshop: Anthropological Genetics and Primate Genetics, San Antonio, Texas, November 19-21, 1998.
Participant, the 2nd Research Symposium on the Genetics of Diabetes, American Diabetes Association, San Jose, CA, October 17-19, 1999.
Speaker, Department of Medicine Research Conference, “Genetics of Type 2 Diabetes in Mexican Americans,” University of Texas Health Science Center at San Antonio, San Antonio,
41 TX, February 23, 1999.
Speaker, Department of Medicine Research Conference, “Genetics of Phenotypes Related to Type 2 Diabetes: The San Antonio Family Diabetes Study,” University of Texas Health Science Center at San Antonio, San Antonio, TX, February 13, 2001.
Invited Speaker at the American Diabetes Association’s 62nd Scientific Sessions, Genetics of Type 2 Diabetes Symposium: “Chromosome 10q and Other Findings from the San Antonio Family Diabetes Study,” San Francisco, California, June 14-18, 2002.
Invited Speaker at the Congreso Internacional Nutriología y Obesidad : “Genetics of Insulin Resistance Syndrome in Mexican Americans,” Monterrey, Mexico, July 5, 2003.
Invited Speaker at the Indo-US Workshop on “Genetics of Complex Diseases with an Emphasis on Type 2 Diabetes,” held in Visakhapatnam, Andhra Pradesh (State), March 30-April1 2004.
Invited Speaker at the American Association of Physical Anthropologists 73rd Annual Meeting, QTL (Quantitative Trait Loci) mapping in biological anthropology Symposium: “QTL mapping in biological anthropology: Obesity,” Tampa, Florida, April 14-17, 2004. Invited Speaker, “Genetics of type 2 diabetes and related phenotypes”, Division of Endocrinology, Department of Medicine (Academy Series), Andhra Medical College, Visakhapatnam, AP, India, June 29th, 2004.
Invited Speaker, Special Lecture: “Identification of susceptibility genes for type 2 Diabetes and related phenotypes in Mexican Americans,” Department of Anthropology, Sri Venkateswara University, Tirupathi, AP, India, July 1, 2004.
Invited Speaker, “Identification of susceptibility genes for type 2 diabetes and its related phenotypes”, International Symposium: “Genomic bases of complex diseases: Obesity and type 2 diabetes,” Mexico City, Mexico, July 16th, 2004.
Invited Speaker, “Genetics of diabetic nephropathy related phenotypes in Mexican Americans,” Genetics and Epidemiology Section, Joslin Diabetes Center, Boston, MA, September 30th, 2004.
Invited Speaker, Genetics Seminar, “Genetics of Metabolic Syndrome in Mexican Americans,” January 21st, 2005, Department of Pediatrics, UT Health Science Center, San Antonio, TX.
Invited Speaker, Symposium: The genetics of comorbidities of obesity, “Genetics of Diabesity”, NAASO annual meetings, Vancouver, Canada, October 15-19, 2005.
Invited Distinguished Speaker, “Diabesity, Genome Scans, and Gene Discovery” International Conference on Bioinformatics and Diabetes Mellitus, held at Andhra University College of Engineering, Visakhapatnam, India, March 25-27, 2006.
Invited (Guest) Speaker, Special Lecture: “Genetics of Complex Diseases with Special Reference to Type 2 Diabetes and Obesity”, sponsored by Department of Anthropology, Andhra University, Visakhapatnam, India, April 3, 2006.
42 Invited Speaker/Faculty, “Type 2 Diabetes and Related Traits, Genome Scans, and Gene Discovery”, Diversity to Discovery: A training course in Genetic Epidemiology and Molecular Genetics, Anthopological Survey of India, Mysore, Karnataka, India, March 31-April 22, 2007.
Invited Speaker, “Genetics of Metabolic Syndrome in Mexican Americans”, American Association of Anthropological Geneticists (AAAG)/Southwest Foundation for Biomedical Research (SFBR) Workshop on Anthropological and Primate Genetics, August 16-18, 2007, SFBR, San Antonio, Texas.
Invited Speaker, “Genetics of Type 2 Diabetes and Related Traits, Genome-Wide Screens, and Susceptibility Gene Discovery”, 33rd Annual Conference of the Indian Society of Human Genetics and International Symposium on Genetics Revisited: the Genomics and Proteomics Advantage, Andhra University, Visakhapatnam, A.P., 11th-13th February, 2008.
Invited Speaker, “Genetics of Complex Diseases, Genome-Wide Scans, and Susceptibility Gene Discovery”, Anthropological Survey of India and International School of Anthropology, Mysore, Karnataka (state), India/ Diversity to Discovery: A training course in Genetic Epidemiology and Molecular Genetics, February 20, 2008.
Invited Speaker, “Genetics of Diabetes in Mexican Americans”, CME program, Texas Diabetes Institute, San Antonio, TX, September 27, 2008.
Invited Speaker, “Genetics of Metabolic Syndrome in Mexican Americans”, 34th Annual Conference of the Indian Society of Human Genetics and International Symposium on Ethics, Culture, and Population Genomics, New Delhi, India, March 17-20, 2009.
Invited Speaker/Faculty, “Genetics of Type 2 Diabetes”, Diversity to Discovery: A training course in Genetic Epidemiology and Molecular Genetics, Anthropological Survey of India, Mysore, Karnataka, India, March 13, 2009.
Invited Speaker/Faculty, “Genetics of Birth Weight and Its Association with Metabolic Syndrome Related Phenotypes”, Diversity to Discovery: A training course in Genetic Epidemiology and Molecular Genetics, Anthropological Survey of India, Mysore, Karnataka, India, March 15, 2009.
Invited Speaker, “Genetics of Birth Weight and Prematurity in Mexican Americans “, Division of Neonatology, Department of Pediatrics, UT Health Science Center, San Antonio, TX, August 20, 2009.
Invited Speaker, Center for Pregnancy and Newborn Research Seminar Series, “Genetics of Birth Weight and Its Association with Metabolic Syndrome Related Phenotypes in Mexican Americans”, Department of Obstetrics and Gynecology, UT Health Science Center, San Antonio, TX, January 28, 2010.
Invited Speaker, “Genetics of Metabolic Syndrome in Mexican Americans”, Pediatric Endocrinology Faculty and Fellows, Santa Rosa Hospital, Center for Children and Families, and UT Health Science Center, San Antonio, TX, August 27, 2010.
Invited Speaker, “Genetic Epidemiology of Type 2 Diabetes and Its Related Disease Conditions in Mexican Americans”, College of Public Service, School of Health Sciences, Jackson State
43 University, Jackson, MS, October 19, 2010.
Invited Speaker, “Genetics of Type 2 Diabetes and Obesity”, Diabetes Lecture Series, Division of Diabetes, Department of Medicine, UT Health Science Center, San Antonio, TX, August 24, 2011.
Invited Speaker, “A Potential Mexico-US Collaborative Project on Genetic Epidemiology of Tuberculosis in Mexican Populations from Chihuahua, Mexico”, Laboratory of Molecular Microbiology, St. Petersburg Pasteur Institute, St. Petersburg, Russia, October 18, 2011.
Speaker and Participant, NIDDK/NIH Workshop: Family-based Studies of the Genetics of Diabetic Kidney Disease, Bethesda, MD, February 7, 2013.
Guest Speaker, “Genetics of Complex Diseases”, Department of Genetics, Sri Ramachandra University, Chennai (Madras), India, November 5, 2013.
Presenter and Participant, T2D-GENES and AMP T2D-GENES Workshop and Meeting, Washington DC, June 16, 2015.
Speaker and Participant, India - U.S. Bilateral Collaborative Research Partnership (CRP) on Diabetes Research – Inaugural Meeting, Sri Ramachandra University, Porur, Chennai, Tamil Nadu, India, June 4-5, 2016.
Guest Speaker, “Indo-US Bilateral Collaborative Research Partnerships (CRP) on Diabetes Research”, Narayana Medical College and Hospital (NMC), Nellore, Andhra Pradesh, India, June 7, 2016.
Plenary Speaker, “Genetic Epidemiology of Type 2 Diabetes and Related Diseases in Mexican Americans: From Bench to Bedside – Are We There Yet? School of Medicine Inaugural Research Symposium, UTRGV, McAllen, TX, August 12, 2017.
Invited Speaker, Division of Nephrology, Department of Medicine, University of Texas Health San Antonio (UTHSA), San Antonio, TX. “The search for genetic factors influencing risk of type 2 diabetes and its related traits: The San Antonio Mexican American Family Studies”. June 14, 2018.
RESEARCH SUPPORT:
ACTIVE:
Source: NIH/NIDDK 5 U01 DK085524 (Contact PI: R. Duggirala and PIs: J. Blangero, R.A. DeFronzo, D.M. Lehman, and F. Thameem) Title: Discovery of functional variants in type 2 diabetes genes in Mexican Americans Period: 05-01-2015 to 04-30-2021 (NCE) Role: Contact Principal Investigator
Source: NIH/NIDDK 1 R21 DK105913 (Contact PI: R. Duggirala and PI: D.K. Sanghera) Title: Genetics of type 2 diabetes in Indian Populations: US-India collaboration project Period: 04-08-2016 to 03-31-2020 (NCE)
44 Role: Contact Principal Investigator
Source: NIH/NIMHD 1 R01 MD012564 (Contact PI: J. Blangero and G.D. Clarke) Title: Identification of the exposome in fatty liver disease in Mexican American families using genetic correction Period: 04-27-2018 to 11-30-2022 Role: Co-Investigator
Source: NIH/NIDDK 1 R01 DK114661 (PI: D.M. Lehman) Title: Human hypothalamic neuronal epigenomics and risk for obesity Period: 09-15-2018 to 06-30-2022 Role: Co-Investigator
Source: NIH/NIA 1 R01 AG058464 (Contact PI: D. Glahn and PI: J. Blangero) Title: Imaging genomics of aging brain Period: 09-30-2018 to 05-31-2023 Role: Co-Investigator
Source: NIH/NIDDK 1 R01 DK118427-A1 (Contact PI: D. K. Sanghera and PIs: R. Duggirala and HHH Göring) Title: Genome, Metabolome, Ancestry and Diabetes Health Disparity Period: 09-05-2019 to 08-31-2023 Role: Principal Investigator
GRANTS PENDING:
Source: NIH/NIDDK 1 R01 MD014629-01A1 (Contact PI: R. Duggirala and PI: J.C. Lopez- Alvarenga) Title: Impact of Socio-Environmental Factors on Cardiometabolic Risk and Epigenetic Signatures in Mexican American Youth Period: 07-01-2020 to 06-30-2025 Role: Contact Principal Investigator Status: Pending but may not be funded (Score 41%; Previous Score 9%)/to be resubmitted.
Source: NIH/NINR 1 R01 R01NR019634 (Contact PI: R. Duggirala and PIs: C.P. Jenkinson, S. Pasupuleti, Golla V). Title: Detection of Environmental Stressors Affecting Childhood Obesity in Mexican Americans: Research to Action through Community Engagement for Health Equity Period: 09-01-2020 to 08-31-2025 Role: Contact Principal Investigator Status: Submitted.
Source: NIH/NIDDK 1 R01DK127016 (Contact PI: R. Arya, S. Mummidi, J.C. Lopez-Alvarenga, B. Tapia) Title: Increased burden of obesity and type 2 diabetes in Mexican Americans of rural colonias of the Lower Rio Grande Valley: the role of environmental stressors, genetic, and epigenetic factors Period: 09-01-2020 to 08-31-2025 Role: Co-Investigator
45 Status: Submitted.
PAST FUNDING (last five years):
Source: NIH/NHLBI 1R01 HL113323 (PIs: J. Blangero and J.E. Curran) Title: Whole genome sequencing to identify causal genetic variants influencing CVD risk Period: 04-01-12 to 03-31-18 (NCE) Role: Co-Investigator
Source: NIH/NHLBI 1R01 HL085742-01-A2 (PI: I. del Rincon) Title: Effect of chronic inflammation on atherosclerosis outcomes in RA Period: 03-13-08 to 02-29-16 (NCE) Role: Co-Investigator
Source: NIH/NIMH 5R01 MH078111 (PI: J. Blangero) Title: Genetics of brain structure and function Period: 01-01-13 to 01-31-16 Role: Co-Investigator
Source: NIH/NIDDK 5 U01 DK085524 (Contact PI: R. Duggirala and PIs: late H.E. Abboud, J. Blangero, R.A. DeFronzo, D.M. Lehman) Title: Discovery of functional variants in type 2 diabetes genes in Mexican Americans Period: 09-20-09 to 04-31-15 Role: Contact Principal Investigator
Source: NIH/NIDDK 1R01 DK084289-01A2 (PI: J. Kent) Title: Gene networks for differential risk of kidney damage by long-term diabetes Period: 09-20-11 to 06-30-15 Role: Co-Investigator
46