Medical Image Computing and Computer Assisted Intervention – MICCAI 2019 22Nd International Conference Shenzhen, China, October 13–17, 2019 Proceedings, Part V

Founding Editors Gerhard Goos Karlsruhe Institute of Technology, Karlsruhe, Germany Juris Hartmanis Cornell University, Ithaca, NY, USA

Editorial Board Members Elisa Bertino Purdue University, West Lafayette, IN, USA Wen Gao Peking University, Beijing, China Bernhard Steffen TU Dortmund University, Dortmund, Germany Gerhard Woeginger RWTH Aachen, Aachen, Germany Moti Yung Columbia University, New York, NY, USA More information about this series at http://www.springer.com/series/7412 Dinggang Shen • Tianming Liu • Terry M. Peters • Lawrence H. Staib • Caroline Essert • Sean Zhou • Pew-Thian Yap • Ali Khan (Eds.)

Medical Image Computing and Computer Assisted Intervention – MICCAI 2019 22nd International Conference Shenzhen, China, October 13–17, 2019 Proceedings, Part V

123 Editors Dinggang Shen Tianming Liu University of North Carolina University of Georgia at Chapel Hill Athens, GA, USA Chapel Hill, NC, USA Lawrence H. Staib Terry M. Peters Yale University Western University New Haven, CT, USA London, ON, Canada Sean Zhou Caroline Essert United Imaging Intelligence University of Strasbourg Shanghai, China Illkirch, France Ali Khan Pew-Thian Yap Western University University of North Carolina London, ON, Canada at Chapel Hill Chapel Hill, NC, USA

ISSN 0302-9743 ISSN 1611-3349 (electronic) Lecture Notes in Computer Science ISBN 978-3-030-32253-3 ISBN 978-3-030-32254-0 (eBook) https://doi.org/10.1007/978-3-030-32254-0

LNCS Sublibrary: SL6 – Image Processing, Computer Vision, Pattern Recognition, and Graphics

© Springer Nature Switzerland AG 2019, corrected publication 2019 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This Springer imprint is published by the registered company Springer Nature Switzerland AG The registered company address is: Gewerbestrasse 11, 6330 Cham, Switzerland Preface

We are pleased to present the proceedings for the 22nd International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI), which was held at the InterContinental Hotel, Shenzhen, China, October 13–17, 2019. The conference also featured 34 workshops, 13 tutorials, and 22 challenges held on October 13 or 17. MICCAI 2019 had an approximately 63% increase in submissions and accepted papers compared with MICCAI 2018. These papers, which comprise six volumes of Lecture Notes in Computer Science (LNCS) proceedings, were selected after a thorough double-blind peer-review process. Following the example set by the previous program chairs of MICCAI 2018 and 2017, we employed Microsoft’s Conference Managing Toolkit (CMT) for paper submissions and double-blind peer-reviews, and the Toronto Paper Matching System (TPMS) to assist with automatic paper assignment to area chairs and reviewers. From 2625 original intentions to submit, 1809 full submissions were received and sent out to peer-review. Of these, 63% were considered as pure Medical Image Computing (MIC), 5% as pure Computer-Assisted Interventions (CAI), and 32% as both MIC and CAI. The MICCAI 2019 Program Committee (PC) comprised 69 area chairs, with 25 from the Americas, 21 from Europe, and 23 from Asia/Pacific/Middle East. Each area chair was assigned *25 manuscripts, with up to 15 suggested potential reviewers using TPMS scoring and self-declared research areas. Subsequently, over 1200 invited reviewers were asked to bid for the papers for which they had been suggested. Final reviewer allocations via CMT took account of PC suggestions, reviewer bidding, and TPMS scores, finally allocating 5–6 papers per reviewer. Based on the double-blinded reviews, 306 papers (17%) were accepted immediately, and 920 papers (51%) were rejected, with the remainder being sent for rebuttal. These decisions were confirmed by the area chairs. During the rebuttal phase, two additional area chairs were assigned to each rebuttal paper using CMT and TPMS scores, who then independently scored them to accept or reject, based on the reviews, rebuttal, and manuscript, resulting in clear paper decisions using majority voting. This process resulted in the acceptance of further 234 papers for an overall acceptance rate of 30%. Regional PC teleconferences were held in late June to confirm the final results and collect PC feedback on the peer-review process. For the MICCAI 2019 proceedings, 538 accepted papers have been organized in six volumes as follows: Part I, LNCS Volume 11764: Optical Imaging; Endoscopy; Microscopy Part II, LNCS Volume 11765: Image Segmentation; Image Registration; Cardiovascular Imaging; Growth, Development, Atrophy, and Progression Part III, LNCS Volume 11766: Neuroimage Reconstruction and Synthesis; Neuroimage Segmentation; Diffusion-Weighted Magnetic Resonance Imaging; Functional Neuroimaging (fMRI); Miscellaneous Neuroimaging vi Preface

Part IV, LNCS Volume 11767: Shape; Prediction; Detection and Localization; Machine Learning; Computer-Aided Diagnosis; Image Reconstruction and Synthesis Part V, LNCS Volume 11768: Computer-Assisted Interventions; MIC Meets CAI Part VI, LNCS Volume 11769: Computed Tomography; X-ray Imaging We would like to thank everyone who contributed to the success of MICCAI 2019 and the quality of its proceedings, particularly the MICCAI Society for support, insightful comments, and providing funding for Kitty Wong to be the ongoing Conference System Manager. Given the increase in workload for this year’s meeting, the Program Committee simply could not have functioned effectively without her, and she will provide ongoing oversight of the review process for future MICCAI conferences. Without the dedication and support of all of the organizers of the workshops, tutorials, and challenges, under the guidance of Kenji Suzuki, together with satellite event chairs Hongen Liao, Qian Wang, Luping Zhou, Hayit Greenspan, and Bram van Ginneken, none of these peripheral events would have been feasible. Also, the Industry Forum (led by Xiaodong Tao and Yiqiang Zhan), the Industry Session (led by Sean Zhou), as well as the Doctoral Symposium (led by Junzhou Huang and Dajiang Zhu) brought new events to MICCAI 2019. The publication chairs, Li Wang and Gang Li, undertook the onerous task of assembling the camera-ready proceedings for publication by Springer. Behind the scenes, MICCAI secretariat personnel, Janette Wallace and Johanne Langford, kept a close eye on logistics and budgets, while Doris Lam and her team from Momentous Asia, this year’s Professional Conference Organization, along with the Local Organizing Committee chair, Dong Ni (together with Jing Qin, Qianjin Feng, Dong Liang, Xiaoying Tang), handled the website and local organization. The Student Travel Award Committee chaired by Huiguang He, Jun Shi, and Xi Jiang evaluated numerous applications, including awards for undergraduate students, which is new in the history of MICCAI. We also thank our sponsors for their ﬁnancial support and presence on site. We are especially grateful to all members of the Program Committee for their diligent work in the reviewer assignments and ﬁnal paper selection, as well as the reviewers for their support during the entire process. Finally, and most importantly, we thank all authors, co-authors, students/postdocs, and supervisors, for submitting and presenting their high-quality work that made MICCAI 2019 a greatly enjoyable, informative, and successful event. We are indebted to those reviewers and PC members who helped us resolve issues relating to last-minute missing reviews. Overall, we thank all of the authors and attendees for making MICCAI 2019 a spectacular success. We look forward to seeing you in Lima, Peru at MICCAI 2020!

October 2019 Dinggang Shen Tianming Liu Terry M. Peters Lawrence H. Staib Caroline Essert Sean Zhou Pew-Thian Yap Ali Khan Organization

General Chairs

Dinggang Shen The University of North Carolina at Chapel Hill, USA Tianming Liu The University of Georgia, USA

Program Executive

Terry Peters Robarts Research Institute, Western University, Canada Lawrence H. Staib Yale University, USA Sean Zhou United Imaging Intelligence (UII), China Caroline Essert University of Strasbourg, France Pew-Thian Yap The University of North Carolina at Chapel Hill, USA Ali Khan Robarts Research Institute, Western University, Canada

Submissions Manager

Kitty Wong Robarts Research Institute, Western University, Canada

Workshops/Challenges/Tutorial Chairs

Kenji Suzuki Illinois Institute of Technology, USA Hayit Greenspan Tel Aviv University, Israel Bram van Ginneken Radboud University Medical Center, The Netherlands Qian Wang Shanghai Jiao Tong University, China Luping Zhou The University of Sydney, Australia Hongen Liao Tsinghua University, China

MICCAI Society, Board of Directors

Leo Joskowicz (President) The Hebrew University of Jerusalem, Israel Stephen Aylward Kitware, Inc., NY, USA (Treasurer) Josien Pluim (Secretary) Eindhoven University of Technology, The Netherlands Wiro Niessen Erasmus Medical Centre, The Netherlands (Past President) Marleen de Bruijne Erasmus Medical Centre, The Netherlands and University of Copenhagen, Denmark Hervé Delinguette Inria, Sophia Antipolis, France Caroline Essert University of Strasbourg, France Alejandro Frangi University of Leeds, UK Lena Maier-Hein German Cancer Research Center, Germany viii Organization

Shuo Li Western University, London, Canada Tianming Liu University of Georgia, USA Anne Martel University of Toronto, Canada Daniel Racoceanu Pontiﬁcal Catholic University of Peru, Peru Julia Schnabel King’s College, London, UK Guoyan Zheng Institute for Surgical Technology & Biomechanics, Switzerland Kevin Zhou Chinese Academy of Sciences, China

Industry Forum

Xiaodong Tao iFLYTEK Health, China Yiqiang Zhan United Imaging Intelligence (UII), China

Publication Committee

Gang Li The University of North Carolina at Chapel Hill, USA Li Wang The University of North Carolina at Chapel Hill, USA

Finance Committee

Dong Ni Shenzhen University, China Janette Wallace Robarts Research Institute, Western University, Canada Stephen Aylward Kitware, Inc., USA

Local Organization Chairs

Dong Ni Shenzhen University, China Jing Qin The Hong Kong Polytechnic University, SAR China Qianjin Feng Southern Medical University, China Dong Liang Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, China Xiaoying Tang Southern University of Science and Technology, China

Sponsors and Publicity Liaison

Kevin Zhou Institute of Computing Technology, Chinese Academy of Sciences, China Hongen Liao Tsinghua University, China Wenjian Qin Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, China Organization ix

Keynote Lectures Chairs

Max Viergever University Medical Center Utrecht, The Netherlands Kensaku Mori Nagoya University, Japan Gözde Ünal Istanbul Technical University, Turkey

Student Travel Award Committee

Huiguang He Institute of Automation, Chinese Academy of Sciences, China Jun Shi Shanghai University, China Xi Jiang University of Electronic Science and Technology of China, China

Student Activities Liaison

Julia Schnabel King’s College London, UK Caroline Essert University of Strasbourg, France Dimitris Metaxas Rutgers University, USA MICCAI Student Board Members

Area Chairs

Purang Abolmaesumi The University of British Columbia, Canada Shadi Albarqouni The Technical University of Munich (TUM), Germany Elsa Angelini Imperial College London, UK Suyash Awate Indian Institute of Technology (IIT) Bombay, India Ulas Bagci University of Central Florida (UCF), USA Kayhan Batmanghelich University of Pittsburgh, USA Christian Baumgartner Swiss Federal Institute of Technology Zurich, Switzerland Ismail Ben Ayed Ecole de Technologie Superieure (ETS), Canada Weidong Cai The University of Sydney, Australia Xiaohuan Cao United Imaging Intelligence (UII), China Elvis Chen Robarts Research Institute, Western University, Canada Xinjian Chen Soochow University, China Jian Cheng Beihang University, China Jun Cheng Cixi Institute of Biomedical Engineering, Chinese Academy of Sciences, China Veronika Cheplygina Eindhoven University of Technology, The Netherlands Elena De Momi Politecnico di Milano, Italy Ayman El-Baz University of Louisville, USA Aaron Fenster Robarts Research Institute, Western University, USA Moti Freiman Philips Healthcare, The Netherlands Yue Gao Tsinghua University, China x Organization

Xiujuan Geng Chinese University of Hong Kong, SAR China Stamatia Giannarou Imperial College London, UK Orcun Goksel Swiss Federal Institute of Technology Zurich, Switzerland Xiao Han AI Healthcare Center, Tencent Inc., China Huiguang He Institute of Automation, Chinese Academy of Sciences, China Yi Hong The University of Georgia, USA Junzhou Huang The University of Texas at Arlington, USA Xiaolei Huang The Pennsylvania State University, USA Juan Eugenio Iglesias University College London, UK Pierre Jannin The University of Rennes, France Bernhard Kainz Imperial College London, UK Ali Kamen Siemens Healthcare, USA Jaeil Kim Kyungpook National University, South Korea Andrew King King’s College London, UK Karim Lekadir Universitat Pompeu Fabra, Spain Cristian Linte Rochester Institute of Technology, USA Mingxia Liu The University of North Carolina at Chapel Hill, USA Klaus Maier-Hein German Cancer Research Center, Germany Anne Martel Sunnybrook Research Institute, USA Andrew Melbourne University College London, UK Anirban Mukhopadhyay Technische Universität Darmstadt, Germany Anqi Qiu National University of Singapore, Singapore Islem Rekik Istanbul Technical University, Turkey Hassan Rivaz Concordia University, USA Feng Shi United Imaging Intelligence (UII), China Amber Simpson Memorial Sloan Kettering Cancer Center, USA Marius Staring Leiden University Medical Center, The Netherlands Heung-Il Suk Korea University, South Korea Tanveer Syeda-Mahmood University Medical Center Utrecht, The Netherlands Xiaoying Tang Southern University of Science and Technology, China Pallavi Tiwari Case Western Reserve University, USA Emanuele Trucco University of Dundee, UK Martin Urschler Graz University of Technology, Austria Hien Van Nguyen University of Houston, USA Archana Venkataraman Johns Hopkins University, USA Christian Wachinger Ludwig Maximilian University of Munich, Germany Linwei Wang Rochester Institute of Technology, USA Yong Xia Northwestern Polytechnical University, China Yanwu Xu Baidu Inc., China Zhong Xue United Imaging Intelligence (UII), China Pingkun Yan Rensselaer Polytechnic Institute, USA Xin Yang Huazhong University of Science and Technology, China Yixuan Yuan City University of Hong Kong, SAR China Organization xi

Daoqiang Zhang Nanjing University of Aeronautics and Astronautics, China Miaomiao Zhang Washington University in St. Louis, USA Tuo Zhang Northwestern Polytechnical University, China Guoyan Zheng Shanghai Jiao Tong University, China S. Kevin Zhou Institute of Computing Technology, Chinese Academy of Sciences, China Dajiang Zhu The University of Texas at Arlington, USA

Reviewers

Abdi, Amir Barbu, Adrian Abduljabbar, Khalid Bardosi, Zoltan Adeli, Ehsan Bateson, Mathilde Aganj, Iman Bathula, Deepti Aggarwal, Priya Batmanghelich, Kayhan Agrawal, Praful Baumgartner, Christian Ahmad, Ola Baur, Christoph Ahmad, Sahar Baxter, John Ahn, Euijoon Bayramoglu, Neslihan Akbar, Shazia Becker, Benjamin Akhondi-Asl, Alireza Behnami, Delaram Akram, Saad Beig, Niha Al-Kadi, Omar Belyaev, Mikhail Alansary, Amir Benkarim, Oualid Alghamdi, Hanan Bentaieb, Aicha Ali, Sharib Bernal, Jose Allan, Maximilian Beyeler, Michael Amiri, Mina Bhatia, Parmeet Anton, Esther Bhole, Chetan Anwar, Syed Bhushan, Chitresh Armin, Mohammad Bi, Lei Audigier, Chloe Bian, Cheng Aviles-Rivero, Angelica Bilinski, Piotr Awan, Ruqayya Bise, Ryoma Awate, Suyash Bnouni, Nesrine Aydogan, Dogu Bo, Wang Azizi, Shekoofeh Bodenstedt, Sebastian Bai, Junjie Bogunovic, Hrvoje Bai, Wenjia Bozorgtabar, Behzad Balbastre, Yaël Bragman, Felix Balsiger, Fabian Braman, Nathaniel Banerjee, Abhirup Bridge, Christopher Bano, Sophia Broaddus, Coleman xii Organization

Bron, Esther Chen, Jie Brooks, Rupert Chen, Jingyun Bruijne, Marleen Chen, Lei Bühler, Katja Chen, Liang Bui, Duc Chen, Min Burlutskiy, Nikolay Chen, Pingjun Burwinkel, Hendrik Chen, Qingchao Bustin, Aurelien Chen, Xiao Cabeen, Ryan Chen, Xiaoran Cai, Hongmin Chen, Xin Cai, Jinzheng Chen, Xuejin Cai, Yunliang Chen, Yang Camino, Acner Chen, Yuanyuan Cao, Jiezhang Chen, Yuncong Cao, Qing Chen, Zhiqiang Cao, Tian Chen, Zhixiang Carapella, Valentina Cheng, Jun Cardenes, Ruben Cheng, Li Cardoso, M. Cheng, Yuan Carolus, Heike Cheng, Yupeng Castro, Daniel Cheriet, Farida Cattin, Philippe Chong, Minqi Chabanas, Matthieu Choo, Jaegul Chaddad, Ahmad Christiaens, Daan Chaitanya, Krishna Christodoulidis, Argyrios Chakraborty, Jayasree Christodoulidis, Stergios Chakraborty, Rudrasis Chung, Ai Chang, Ken Çiçek, Özgün Chang, Violeta Cid, Yashin Charaborty, Tapabrata Clarkson, Matthew Chatelain, Pierre Clough, James Chatterjee, Sudhanya Collins, Toby Chen, Alvin Commowick, Olivier Chen, Antong Conze, Pierre-Henri Chen, Cameron Cootes, Timothy Chen, Chao Correia, Teresa Chen, Chen Coulon, Olivier Chen, Elvis Coupé, Pierrick Chen, Fang Courtecuisse, Hadrien Chen, Fei Craley, Jeffrey Chen, Geng Crimi, Alessandro Chen, Hanbo Cury, Claire Chen, Hao D’souza, Niharika Chen, Jia-Wei Dai, Hang Chen, Jialei Dalca, Adrian Chen, Jianxu Das, Abhijit Organization xiii

Das, Dhritiman Esteban, Oscar Deeba, Farah Fan, Jingfan Dekhil, Omar Fan, Xin Demiray, Beatrice Fan, Yong Deniz, Cem Fan, Yonghui Depeursinge, Adrien Fang, Xi Desrosiers, Christian Farag, Aly Dewey, Blake Farzi, Mohsen Dey, Raunak Fauser, Johannes Dhamala, Jwala Fawaz, Hassan Ding, Meng Fedorov, Andrey Distergoft, Alexander Fehri, Hamid Dobrenkii, Anton Feng, Chiyu Dolz, Jose Feng, Jun Dong, Liang Feng, Xinyang Dong, Mengjin Feng, Yuan Dong, Nanqing Fenster, Aaron Dong, Xiao Ferrante, Enzo Dong, Yanni Feydy, Jean Dou, Qi Fischer, Lukas Du, Changde Fischer, Peter Du, Lei Fishbaugh, James Du, Shaoyi Fletcher, Tom Duan, Dingna Flores, Kevin Duan, Lixin Forestier, Germain Dubost, Florian Forkert, Nils Duchateau, Nicolas Fotouhi, Javad Duncan, James Fountoukidou, Tatiana Duong, Luc Franz, Alfred Dvornek, Nicha Frau-Pascual, Aina Dzyubachyk, Oleh Freysinger, Wolfgang Eaton-Rosen, Zach Fripp, Jurgen Ebner, Michael Fu, Huazhu Ebrahimi, Mehran Funka-Lea, Gareth Edwards, Philip Funke, Isabel Egger, Bernhard Funke, Jan Eguizabal, Alma Fürnstahl, Philipp Einarsson, Gudmundur Furukawa, Ryo Ekin, Ahmet Gahm, Jin Elazab, Ahmed Galassi, Francesca Elhabian, Shireen Galdran, Adrian Elmogy, Mohammed Gan, Yu Eltanboly, Ahmed Gao, Fei Erdt, Marius Gao, Mingchen Ernst, Floris Gao, Siyuan Esposito, Marco Gao, Zhifan xiv Organization

Gardezi, Syed Hamze, Noura Ge, Bao Han, Hu Gerber, Samuel Han, Jungong Gerig, Guido Han, Xiaoguang Gessert, Nils Han, Xu Gevaert, Olivier Han, Zhi Gharabaghi, Sara Hancox, Jonny Ghesu, Florin Hanson, Erik Ghimire, Sandesh Hao, Xiaoke Gholipour, Ali Haq, Rabia Ghosal, Sayan Harders, Matthias Giraud, Rémi Harrison, Adam Glocker, Ben Haskins, Grant Goceri, Evgin Hatamizadeh, Ali Goetz, Michael Hatt, Charles Gomez, Alberto Hauptmann, Andreas Gong, Kuang Havaei, Mohammad Gong, Mingming He, Tiancheng Gonzalez, German He, Yufan Gopal, Sharath Heimann, Tobias Gopinath, Karthik Heldmann, Stefan Gordon, Shiri Heller, Nicholas Gori, Pietro Hernandez-Matas, Carlos Gou, Shuiping Hernandez, Monica Granados, Alejandro Hett, Kilian Grau, Vicente Higger, Matt Green, Michael Hinkle, Jacob Gritsenko, Andrey Ho, Tsung-Ying Grupp, Robert Hoffmann, Nico Gu, Lin Holden, Matthew Gu, Yun Hong, Song Gu, Zaiwang Hong, Sungmin Gueziri, Houssem-Eddine Hou, Benjamin Guo, Hengtao Hsu, Li-Ming Guo, Jixiang Hu, Dan Guo, Xiaoqing Hu, Kai Guo, Yanrong Hu, Xiaowei Guo, Yong Hu, Xintao Gupta, Kratika Hu, Yan Gupta, Vikash Hu, Yipeng Gutman, Boris Huang, Heng Gyawali, Prashnna Huang, Huifang Hacihaliloglu, Ilker Huang, Jiashuang Hadjidemetriou, Stathis Huang, Kevin Haldar, Justin Huang, Ruobing Hamarneh, Ghassan Huang, Shih-Gu Organization xv

Huang, Weilin Jud, Christoph Huang, Xiaolei Jung, Kyu-Hwan Huang, Yawen Jungo, Alain Huang, Yixing Kadkhodamohammadi, Abdolrahim Huang, Yufang Kakileti, Siva Huang, Zhongwei Kamnitsas, Konstantinos Huaulmé, Arnaud Kang, Eunsong Huisman, Henkjan Kao, Po-Yu Huo, Xing Kapoor, Ankur Huo, Yuankai Karani, Neerav Husch, Andreas Karayumak, Suheyla Hussein, Sarfaraz Kazi, Anees Hutter, Jana Kerrien, Erwan Hwang, Seong Kervadec, Hoel Icke, Ilknur Khalifa, Fahmi Igwe, Kay Khalili, Nadieh Ingalhalikar, Madhura Khallaghi, Siavash Irmakci, Ismail Khalvati, Farzad Ivashchenko, Oleksandra Khan, Hassan Izadyyazdanabadi, Mohammadhassan Khanal, Bishesh Jafari, Mohammad Khansari, Maziyar Jäger, Paul Khosravan, Naji Jamaludin, Amir Kia, Seyed Janatka, Mirek Kikinis, Ron Jaouen, Vincent Kim, Geena Jarayathne, Uditha Kim, Hosung Javadi, Golara Kim, Hyo-Eun Javer, Avelino Kim, Jae-Hun Jensen, Todd Kim, Jinman Ji, Zexuan Kim, Jinyoung Jia, Haozhe Kim, Minjeong Jiang, Jue Kim, Namkug Jiang, Steve Kim, Seong Jiang, Tingting Kim, Young-Ho Jiang, Weixiong Kitasaka, Takayuki Jiang, Xi Klein, Stefan Jiao, Jianbo Klinder, Tobias Jiao, Jieqing Kolli, Kranthi Jiao, Zhicheng Kong, Bin Jie, Biao Kong, Xiang-Zhen Jin, Dakai Konukoglu, Ender Jin, Taisong Koo, Bongjin Jin, Yueming Koohbanani, Navid John, Rogers Kopriva, Ivica Joshi, Anand Kose, Kivanc Joshi, Shantanu Koutsoumpa, Christina xvi Organization

Kozinski, Mateusz Leow, Wee Krebs, Julian Lessmann, Nikolas Krishnan, Anithapriya Li, Annan Krishnaswamy, Pavitra Li, Bin Krivov, Egor Li, Fuhai Kruggel, Frithjof Li, Gang Krupinski, Elizabeth Li, Guoshi Kuang, Hulin Li, Hongwei Kügler, David Li, Hongying Kuijper, Arjan Li, Huiqi Kulkarni, Prachi Li, Jian Kumar, Arun Li, Jianning Kumar, Ashnil Li, Ke Kumar, Kuldeep Li, Minli Kumar, Neeraj Li, Quanzheng Kumar, Nitin Li, Rongjian Kumaradevan, Punithakumar Li, Shaohua Kunz, Manuela Li, Shulong Kunze, Holger Li, Shuyu Kuo, Weicheng Li, Wenqi Kurc, Tahsin Li, Xiang Kurmann, Thomas Li, Xianjun Kwak, Jin Li, Xiaojie Kwon, Yongchan Li, Xiaomeng Laadhari, Aymen Li, Xiaoxiao Ladikos, Alexander Li, Xiuli Lalonde, Rodney Li, Yang Lamata, Pablo Li, Yuexiang Langs, Georg Li, Zhang Lartizien, Carole Li, Zhi-Cheng Lasso, Andras Li, Zhiyuan Lau, Felix Li, Zhjin Laura, Cristina Lian, Chunfeng Le, Ngan Liang, Jianming Ledig, Christian Liang, Shanshan Lee, Hansang Liang, Yudong Lee, Hyekyoung Liao, Ruizhi Lee, Jong-Hwan Liao, Xiangyun Lee, Kyong Licandro, Roxane Lee, Minho Lin, Hongxiang Lee, Soochahn Lin, Lanfen Léger, Étienne Lin, Muqing Leger, Stefan Lindner, Claudia Lei, Baiying Lippert, Christoph Lekadir, Karim Lisowska, Aneta Lenga, Matthias Litjens, Geert Organization xvii

Liu, Bin Ma, Burton Liu, Daochang Ma, Da Liu, Dong Ma, Kai Liu, Dongnan Ma, Xuelin Liu, Fang Mahapatra, Dwarikanath Liu, Feihong Mahdavi, Sara Liu, Feng Mahmoud, Ali Liu, Hong Maicas, Gabriel Liu, Hui Maier-Hein, Klaus Liu, Jianfei Maier, Andreas Liu, Jiang Makrogiannis, Sokratis Liu, Jin Malandain, Grégoire Liu, Jing Malik, Bilal Liu, Jundong Malpani, Anand Liu, Kefei Mancini, Matteo Liu, Li Manhart, Michael Liu, Mingxia Manjon, Jose Liu, Na Mansoor, Awais Liu, Peng Mao, Yunxiang Liu, Shenghua Martel, Anne Liu, Siqi Martinez-Torteya, Antonio Liu, Siyuan Mathai, Tejas Liu, Tianming Mato, David Liu, Tiffany Mcclelland, Jamie Liu, Xianglong Mcleod, Jonathan Liu, Yixun Medrano-Gracia, Pau Liu, Yong Mehta, Ronak Liu, Yue Meier, Raphael Liu, Zhe Melbourne, Andrew Loddo, Andrea Meng, Qingjie Lopes, Daniel Meng, Xianjing Lorenzi, Marco Meng, Yu Lou, Bin Menze, Bjoern Lu, Allen Mi, Liang Lu, Donghuan Miao, Shun Lu, Jiwen Michielse, Stijn Lu, Le Midya, Abhishek Lu, Weijia Milchenko, Mikhail Lu, Yao Min, Zhe Lu, Yueh-Hsun Miyamoto, Tadashi Luo, Gongning Mo, Yuanhan Luo, Jie Molina, Rafael Lv, Jinglei Montillo, Albert Lyu, Ilwoo Moradi, Mehdi Lyu, Junyan Moreno, Rodrigo Ma, Benteng Mortazi, Aliasghar xviii Organization

Mozaffari, Mohammad Parajuli, Nripesh Muetzel, Ryan Park, Hyunjin Müller, Henning Park, Jongchan Muñoz-Barrutia, Arrate Park, Sanghyun Munsell, Brent Park, Seung-Jong Nadeem, Saad Paschali, Magdalini Nahlawi, Layan Paul, Angshuman Nandakumar, Naresh Payer, Christian Nardi, Giacomo Pei, Yuru Neila, Pablo Peng, Jialin Ni, Dong Peng, Tingying Nichols, Thomas Pennec, Xavier Nickisch, Hannes Perdomo, Oscar Nie, Dong Pereira, Sérgio Nie, Jingxin Pérez-Carrasco, Jose-Antonio Nie, Weizhi Pesteie, Mehran Niethammer, Marc Peter, Loic Nigam, Aditya Peters, Jorg Ning, Lipeng Petitjean, Caroline Niu, Shuaicheng Pezold, Simon Niu, Sijie Pfeiffer, Micha Noble, Jack Phellan, Renzo Noblet, Vincent Phophalia, Ashish Novo, Jorge Pisharady, Pramod O’donnell, Thomas Playout, Clement Obeid, Mohammad Pluim, Josien Oda, Hirohisa Pohl, Kilian Oda, Masahiro Portenier, Tiziano Odry, Benjamin Pouch, Alison Oeltze-Jafra, Steffen Prasanna, Prateek Oksuz, Ilkay Prevost, Raphael Oliveira, Marcelo Ps, Viswanath Oliver, Arnau Pujades, Sergi Oñativia, Jon Qi, Xin Onofrey, John Qian, Zhen Orasanu, Eliza Qiang, Yan Orihuela-Espina, Felipe Qiao, Lishan Orlando, Jose Qiao, Yuchuan Osmanlioglu, Yusuf Qin, Chen Otalora, Sebastian Qin, Wenjian Pace, Danielle Qirong, Bu Pagador, J. Qiu, Wu Pai, Akshay Qu, Liangqiong Pan, Yongsheng Raamana, Pradeep Pang, Shumao Rabbani, Hossein Papiez, Bartlomiej Rackerseder, Julia Organization xix

Rad, Reza Saha, Pramit Rafii-Tari, Hedyeh Sahu, Manish Rajpoot, Kashif Samani, Abbas Ramachandram, Dhanesh Samek, Wojciech Ran, Lingyan Sánchez-Margallo, Francisco Raniga, Parnesh Sánchez-Margallo, Juan Rashwan, Hatem Sankaran, Sethuraman Rathore, Saima Sanroma, Gerard Ratnarajah, Nagulan Sao, Anil Raval, Mehul Sarhan, Mhd Ravikumar, Nishant Sarikaya, Duygu Raviprakash, Harish Sarker, Md. Raza, Shan Sato, Imari Reaungamornrat, Surreerat Saut, Olivier Rekik, Islem Savardi, Mattia Remeseiro, Beatriz Savitha, Ramasamy Rempfler, Markus Scarpa, Fabio Ren, Jian Scheinost, Dustin Ren, Xuhua Scherf, Nico Ren, Yudan Schirmer, Markus Reyes-Aldasoro, Constantino Schlaefer, Alexander Reyes, Mauricio Schmid, Jerome Riedel, Brandalyn Schnabel, Julia Rieke, Nicola Schultz, Thomas Risser, Laurent Schwartz, Ernst Rittner, Leticia Sdika, Michael Rivera, Diego Sedai, Suman Ro, Yong Sekou, Taibou Robinson, Emma Sekuboyina, Anjany Robinson, Robert Selvan, Raghavendra Rodas, Nicolas Semedo, Carla Rodrigues, Rafael Senouf, Ortal Rohr, Karl Seoud, Lama Roohani, Yusuf Sermesant, Maxime Roszkowiak, Lukasz Serrano, Carmen Roth, Holger Sethi, Amit Rouco, José Shaban, Muhammad Roy, Abhijit Shaffie, Ahmed Ruijters, Danny Shah, Meet Rusu, Mirabela Shalaby, Ahmed Rutter, Erica Shamir, Reuben S., Sharath Shan, Hongming Sabuncu, Mert Shao, Yeqin Sachse, Frank Sharma, Harshita Safta, Wiem Shehata, Mohamed Saha, Monjoy Shen, Haocheng xx Organization

Shen, Li Sun, Jian Shen, Mali Sun, Li Shen, Yiru Sun, Tao Sheng, Ke Sung, Kyunghyun Shi, Bibo Suter, Yannick Shi, Jun Tajbakhsh, Nima Shi, Kuangyu Tan, Chaowei Shi, Xiaoshuang Tan, Jiaxing Shi, Yonggang Tan, Wenjun Shi, Yonghong Tang, Min Shigwan, Saurabh Tang, Sheng Shin, Hoo-Chang Tang, Thomas Shin, Jitae Tang, Xiaoying Shontz, Suzanne Tang, Youbao Signoroni, Alberto Tang, Yuxing Siless, Viviana Tang, Zhenyu Silva, Carlos Tanner, Christine Silva, Wilson Tanno, Ryutaro Simonovsky, Martin Tao, Qian Simson, Walter Tarroni, Giacomo Sinclair, Matthew Tasdizen, Tolga Singh, Vivek Thung, Kim Soans, Rajath Tian, Jiang Sohel, Ferdous Tian, Yun Sokooti, Hessam Toews, Matthew Soliman, Ahmed Tong, Yubing Sommen, Fons Topsakal, Oguzhan Sommer, Stefan Torosdagli, Neslisah Song, Ming Toussaint, Nicolas Song, Yang Troccaz, Jocelyne Sotiras, Aristeidis Trzcinski, Tomasz Sparks, Rachel Tulder, Gijs Spiclin, Ziga Tustison, Nick St-Jean, Samuel Tuysuzoglu, Ahmet Steinbach, Peter Ukwatta, Eranga Stern, Darko Unberath, Mathias Stimpel, Bernhard Ungi, Tamas Strait, Justin Upadhyay, Uddeshya Studholme, Colin Urschler, Martin Styner, Martin Uslu, Fatmatulzehra Su, Hai Uyanik, Ilyas Su, Yun-Hsuan Vaillant, Régis Subramanian, Vaishnavi Vakalopoulou, Maria Subsol, Gérard Valindria, Vanya Sudre, Carole Varela, Marta Suk, Heung-Il Varsavsky, Thomas Organization xxi

Vedula, S. Wang, Sheng Vedula, Sanketh Wang, Shuai Veeraraghavan, Harini Wang, Wenzhe Vega, Roberto Wang, Xiangxue Veni, Gopalkrishna Wang, Xiaosong Verma, Ujjwal Wang, Xuchu Vetter, Thomas Wang, Yalin Vialard, Francois-Xavier Wang, Yan Villard, Pierre-Frederic Wang, Yaping Villarini, Barbara Wang, Yuanjun Virga, Salvatore Wang, Ze Vishnevskiy, Valery Wang, Zhe Viswanath, Satish Wang, Zhinuo Vlontzos, Athanasios Wang, Zhiwei Vogl, Wolf-Dieter Wang, Zilei Voigt, Ingmar Weber, Jonathan Vos, Bob Wee, Chong-Yaw Vrtovec, Tomaz Weese, Jürgen Wang, Bo Wei, Benzheng Wang, Changmiao Wei, Dong Wang, Chengjia Wei, Donglai Wang, Chunliang Wei, Dongming Wang, Dadong Weigert, Martin Wang, Guotai Wein, Wolfgang Wang, Haifeng Wels, Michael Wang, Haoqian Wemmert, Cédric Wang, Hongkai Werner, Rene Wang, Hongzhi Wesierski, Daniel Wang, Hua Williams, Bryan Wang, Huan Williams, Jacqueline Wang, Jiazhuo Williams, Travis Wang, Jingwen Williamson, Tom Wang, Jun Wilms, Matthias Wang, Junyan Wiskin, James Wang, Kuanquan Wittek, Adam Wang, Kun Wollmann, Thomas Wang, Lei Wolterink, Jelmer Wang, Li Wong, Ken Wang, Liansheng Woo, Jonghye Wang, Manning Wu, Guoqing Wang, Mingliang Wu, Ji Wang, Nizhuan Wu, Jian Wang, Pei Wu, Jiong Wang, Puyang Wu, Pengxiang Wang, Ruixuan Wu, Xi Wang, Shanshan Wu, Ye xxii Organization

Wu, Yicheng Yang, Xiaohui Wuerfl, Tobias Yang, Xin Xi, Xiaoming Yao, Dongren Xia, Jing Yao, Jianhua Xia, Wenfeng Yao, Jiawen Xiao, Deqiang Ye, Chuyang Xiao, Yiming Ye, Jong Xie, Hai Ye, Menglong Xie, Hongtao Ye, Xujiong Xie, Jianyang Yi, Jingru Xie, Long Yi, Xin Xie, Weidi Ying, Shihui Xie, Yiting Yoo, Youngjin Xie, Yuanpu Yousefi, Bardia Xie, Yutong Yousefi, Sahar Xing, Fuyong Yu, Jinhua Xiong, Tao Yu, Kai Xu, Chenchu Yu, Lequan Xu, Jiaofeng Yu, Renping Xu, Jun Yu, Weichuan Xu, Kele Yushkevich, Paul Xu, Rui Zanjani, Farhad Xu, Ting Zenati, Marco Xu, Yan Zeng, Dong Xu, Yongchao Zeng, Guodong Xu, Zheng Zettinig, Oliver Xu, Zhenlin Zhan, Liang Xu, Zhoubing Zhang, Baochang Xu, Ziyue Zhang, Chuncheng Xue, Jie Zhang, Dongqing Xue, Wufeng Zhang, Fan Xue, Yuan Zhang, Haichong Yahya, Faridah Zhang, Han Yan, Chenggang Zhang, Haopeng Yan, Ke Zhang, Heye Yan, Weizheng Zhang, Jianpeng Yan, Yu Zhang, Jiong Yan, Yuguang Zhang, Jun Yan, Zhennan Zhang, Le Yang, Guang Zhang, Lichi Yang, Guanyu Zhang, Mingli Yang, Hao-Yu Zhang, Pengyue Yang, Jie Zhang, Pin Yang, Lin Zhang, Qiang Yang, Shan Zhang, Rongzhao Yang, Xiao Zhang, Shengping Organization xxiii

Zhang, Shu Zhao, Yu Zhang, Songze Zhao, Zijian Zhang, Tianyang Zheng, Shenhai Zhang, Tong Zheng, Yalin Zhang, Wei Zheng, Yinqiang Zhang, Wen Zhong, Zichun Zhang, Wenlu Zhou, Bo Zhang, Xiang Zhou, Jianlong Zhang, Xin Zhou, Luping Zhang, Yi Zhou, Niyun Zhang, Yifan Zhou, S. Zhang, Yizhe Zhou, Shoujun Zhang, Yong Zhou, Tao Zhang, Yongqin Zhou, Wenjin Zhang, You Zhou, Yuyin Zhang, Yu Zhou, Zhiguo Zhang, Yue Zhu, Hancan Zhang, Yueyi Zhu, Junjie Zhang, Yungeng Zhu, Qikui Zhang, Yunyan Zhu, Weifang Zhang, Yuyao Zhu, Wentao Zhang, Zizhao Zhu, Xiaofeng Zhao, Haifeng Zhu, Xinliang Zhao, Jun Zhu, Yingying Zhao, Qingyu Zhu, Yuemin Zhao, Rongchang Zhu, Zhuotun Zhao, Shijie Zhuang, Xiahai Zhao, Shiwan Zia, Aneeq Zhao, Tengda Zimmer, Veronika Zhao, Wei Zolgharni, Massoud Zhao, Yitian Zou, Ju Zhao, Yiyuan Zuluaga, Maria Accepted MICCAI 2019 Papers

By Region of First Author

Africa, 0%

Asia North America 37% 36%

Australasia 1%

Central/South America, 0.40% Europe 26%

By Technical Keyword

Others Big Data 6% 1% Surgical Planning & Visualization Anatomy & Physiology 3% 4% Neuro Imaging CAD 5% 12%

Microscopy & Histology Reconstruction 5% 7%

Interventions 3%

Machine Learning & AI 28% Segmentation, Registration & Fusion 25% Biomarkers 1% Awards Presented at MICCAI 2018, Granada, Spain

MICCAI Society Enduring Impact Award: The Enduring Impact Award is the highest award of the MICCAI Society. It is a career award for continued excellence in the MICCAI research field. The 2018 Enduring Impact Award was presented to Sandy Wells, Brigham and Women’s Hospital/Harvard Medical School, USA. MICCAI Society Fellowships: MICCAI Fellowships are bestowed annually on a small number of senior members of the society in recognition of substantial scientific contributions to the MICCAI research field and service to the MICCAI community. In 2018, fellowships were awarded to: – Pierre Jannin (Université de Rennes, France) – Anne Martel (University of Toronto, Canada) – Julia Schnabel (King’s College London, UK) Medical Image Analysis Journal Award Sponsored by Elsevier: Jianyu Lin, for his paper entitled “Dual-modality Endoscopic Probe for Tissue Surface Shape Reconstruction and Hyperspectral Imaging Enabled by Deep Neural Networks,” authored by Jianyu Lin, Neil T. Clancy, Ji Qi, Yang Hu, Taran Tatla, Danail Stoyanov, Lena Maier-Hein, and Daniel S. Elson. Best Paper in International Journal of Computer-Assisted Radiology and Surgery (IJCARS) journal: Arash Pourtaherian for his paper entitled “Robust and Semantic Needle Detection in 3D Ultrasound Using Orthogonal-Plane Convolutional Neural Networks,” authored by Arash Pourtaherian, Farhad Ghazvinian Zanjani, Svitlana Zinger, Nenad Mihajlovic, Gary C. Ng, Hendrikus H. M. Korsten, and Peter H. N. de With. Young Scientist Publication Impact Award: MICCAI papers by a young scientist from the past 5 years were eligible for this award. It is made to a researcher whose work had an impact on the MICCAI field in terms of citations, secondary citations, subsequent publications, h-index. The 2018 Young Scientist Publication Impact Award was given to Holger R Roth: “A New 2.5D Representation for Lymph Node Detection Using Random Sets of Deep Convolutional Neural Network Observations” authored by Holger R. Roth, Le Lu, Ari Seff, Kevin M. Cherry, Joanne Hoffman, Shijun Wang, Jiamin Liu, Evrim Turkbey, and Ronald M. Summers. MICCAI Young Scientist Awards: The Young Scientist Awards are stimulation prizes awarded for the best first authors of MICCAI contributions in distinct subject areas. The nominees had to be full-time students at a recognized university at, or within, two years prior to submission. The 2018 MICCAI Young Scientist Awards were given to: – Erik J. Bekkers for the paper entitled: “Roto-Translation Covariant Convolutional Networks for Medical Image Analysis” – Bastian Bier for the paper entitled: “X-ray-transform Invariant Anatomical Landmark Detection for Pelvic Trauma Surgery” xxviii Awards Presented at MICCAI 2018, Granada, Spain

– Yuanhan Mo for his paper entitled: “The Deep Poincaré Map: A Novel Approach for Left Ventricle Segmentation” – Tanya Nair for the paper entitled: “Exploring Uncertainty Measures in Deep Networks for Multiple Sclerosis Lesion Detection and Segmentation” – Yue Zhang for the paper entitled: “Task-Driven Generative Modeling for Unsupervised Domain Adaptation: Application to X-ray Image Segmentation” Contents – Part V

Computer-Assisted Interventions

Robust Cochlear Modiolar Axis Detection in CT ...... 3 Wilhelm Wimmer, Clair Vandersteen, Nicolas Guevara, Marco Caversaccio, and Hervé Delingette

Learning to Avoid Poor Images: Towards Task-aware C-arm Cone-beam CT Trajectories ...... 11 Jan-Nico Zaech, Cong Gao, Bastian Bier, Russell Taylor, Andreas Maier, Nassir Navab, and Mathias Unberath

Optimizing Clearance of Bézier Spline Trajectories for Minimally-Invasive Surgery...... 20 Johannes Fauser, Igor Stenin, Julia Kristin, Thomas Klenzner, Jörg Schipper, and Anirban Mukhopadhyay

Direct Visual and Haptic Volume Rendering of Medical Data Sets for an Immersive Exploration in Virtual Reality ...... 29 Balázs Faludi, Esther I. Zoller, Nicolas Gerig, Azhar Zam, Georg Rauter, and Philippe C. Cattin

Triplet Feature Learning on Endoscopic Video Manifold for Online GastroIntestinal Image Retargeting ...... 38 Yun Gu, Benjamin Walter, Jie Yang, Alexander Meining, and Guang-Zhong Yang

A Novel Endoscopic Navigation System: Simultaneous Endoscope and Radial Ultrasound Probe Tracking Without External Trackers...... 47 Xiongbiao Luo, Hui-Qing Zeng, Yan-Ping Du, and Xiao Cheng

An Extremely Fast and Precise Convolutional Neural Network for Recognition and Localization of Cataract Surgical Tools...... 56 Dongqing Zang, Gui-Bin Bian, Yunlai Wang, and Zhen Li

Semi-autonomous Robotic Anastomoses of Vaginal Cuffs Using Marker Enhanced 3D Imaging and Path Planning ...... 65 M. Kam, H. Saeidi, S. Wei, J. D. Opfermann, S. Leonard, M. H. Hsieh, J. U. Kang, and A. Krieger

ARAMIS: Augmented Reality Assistance for Minimally Invasive Surgery Using a Head-Mounted Display ...... 74 Long Qian, Xiran Zhang, Anton Deguet, and Peter Kazanzides xxx Contents – Part V

Interactive Endoscopy: A Next-Generation, Streamlined User Interface for Lung Surgery Navigation ...... 83 Paul Thienphrapa, Torre Bydlon, Alvin Chen, Prasad Vagdargi, Nicole Varble, Douglas Stanton, and Aleksandra Popovic

Non-invasive Assessment of in Vivo Auricular Cartilage by Ultra-short Ã Echo Time (UTE) T2 Mapping ...... 92 Xue Li, Cheng Zhao, and Weiwei Zhang

INN: Inflated Neural Networks for IPMN Diagnosis ...... 101 Rodney LaLonde, Irene Tanner, Katerina Nikiforaki, Georgios Z. Papadakis, Pujan Kandel, Candice W. Bolan, Michael B. Wallace, and Ulas Bagci

Development of a Multi-objective Optimized Planning Method for Microwave Liver Tumor Ablation ...... 110 Libin Liang, Derek Cool, Nirmal Kakani, Guangzhi Wang, Hui Ding, and Aaron Fenster

Generating Large Labeled Data Sets for Laparoscopic Image Processing Tasks Using Unpaired Image-to-Image Translation ...... 119 Micha Pfeiffer, Isabel Funke, Maria R. Robu, Sebastian Bodenstedt, Leon Strenger, Sandy Engelhardt, Tobias Roß, Matthew J. Clarkson, Kurinchi Gurusamy, Brian R. Davidson, Lena Maier-Hein, Carina Riediger, Thilo Welsch, Jürgen Weitz, and Stefanie Speidel

Mask-MCNet: Instance Segmentation in 3D Point Cloud of Intra-oral Scans...... 128 Farhad Ghazvinian Zanjani, David Anssari Moin, Frank Claessen, Teo Cherici, Sarah Parinussa, Arash Pourtaherian, Svitlana Zinger, and Peter H. N. de With

Physics-Based Deep Neural Network for Augmented Reality During Liver Surgery ...... 137 Jean-Nicolas Brunet, Andrea Mendizabal, Antoine Petit, Nicolas Golse, Eric Vibert, and Stéphane Cotin

Detecting Cannabis-Associated Cognitive Impairment Using Resting-State fNIRS ...... 146 Yingying Zhu, Jodi Gilman, Anne Eden Evins, and Mert Sabuncu

Cross-Domain Conditional Generative Adversarial Networks for Stereoscopic Hyperrealism in Surgical Training ...... 155 Sandy Engelhardt, Lalith Sharan, Matthias Karck, Raffaele De Simone, and Ivo Wolf Contents – Part V xxxi

Free-View, 3D Gaze-Guided Robotic Scrub Nurse ...... 164 Alexandros Kogkas, Ahmed Ezzat, Rudrik Thakkar, Ara Darzi, and George Mylonas

Haptic Modes for Multiparameter Control in Robotic Surgery...... 173 Philipp Schleer, Sergey Drobinsky, Tahany Hmaid, and Klaus Radermacher

Learning to Detect Collisions for Continuum Manipulators Without a Prior Model...... 182 Shahriar Sefati, Shahin Sefati, Iulian Iordachita, Russell H. Taylor, and Mehran Armand

Simulation of Balloon-Expandable Coronary Stent Apposition with Plastic Beam Elements ...... 191 Camille Krewcun, Émilie Péry, Nicolas Combaret, Pascal Motreff, and Laurent Sarry

Virtual Cardiac Surgical Planning Through Hemodynamics Simulation and Design Optimization of Fontan Grafts ...... 200 Byeol Kim, Yue-Hin Loke, Florence Stevenson, Dominik Siallagan, Paige Mass, Justin D. Opfermann, Narutoshi Hibino, Laura Olivieri, and Axel Krieger

3D Modelling of the Residual Freezing for Renal Cryoablation Simulation and Prediction ...... 209 Caroline Essert, Pramod P. Rao, Afshin Gangi, and Leo Joskowicz

A Generative Model of Hyperelastic Strain Energy Density Functions for Real-Time Simulation of Brain Tissue Deformation ...... 218 Alejandro Granados, Martin Schweiger, Vejay Vakharia, Andrew W. McEvoy, Anna Miserocchi, John S. Duncan, Rachel Sparks, and Sébastien Ourselin

Variational Shape Completion for Virtual Planning of Jaw Reconstructive Surgery ...... 227 Amir H. Abdi, Mehran Pesteie, Eitan Prisman, Purang Abolmaesumi, and Sidney Fels

Markerless Image-to-Face Registration for Untethered Augmented Reality in Head and Neck Surgery ...... 236 Christina Gsaxner, Antonio Pepe, Jürgen Wallner, Dieter Schmalstieg, and Jan Egger

Towards a Mixed-Reality First Person Point of View Needle Navigation System ...... 245 Leah Groves, Natalie Li, Terry M. Peters, and Elvis C. S. Chen xxxii Contents – Part V

Concept-Centric Visual Turing Tests for Method Validation ...... 254 Tatiana Fountoukidou and Raphael Sznitman

Transferring from ex-vivo to in-vivo: Instrument Localization in 3D Cardiac Ultrasound Using Pyramid-UNet with Hybrid Loss...... 263 Hongxu Yang, Caifeng Shan, Tao Tan, Alexander F. Kolen, and Peter H. N. de With

A Sparsely Distributed Intra-cardial Ultrasonic Array for Real-Time Endocardial Mapping...... 272 Alon Baram, Hayit Greenspan, and Zvi Freidman

FetusMap: Fetal Pose Estimation in 3D Ultrasound ...... 281 Xin Yang, Wenlong Shi, Haoran Dou, Jikuan Qian, Yi Wang, Wufeng Xue, Shengli Li, Dong Ni, and Pheng-Ann Heng

Agent with Warm Start and Active Termination for Plane Localization in 3D Ultrasound ...... 290 Haoran Dou, Xin Yang, Jikuan Qian, Wufeng Xue, Hao Qin, Xu Wang, Lequan Yu, Shujun Wang, Yi Xiong, Pheng-Ann Heng, and Dong Ni

Learning and Understanding Deep Spatio-Temporal Representations from Free-Hand Fetal Ultrasound Sweeps...... 299 Yuan Gao and J. Alison Noble

User Guidance for Point-of-Care Echocardiography Using a Multi-task Deep Neural Network ...... 309 Grzegorz Toporek, Raghavendra Srinivasa Naidu, Hua Xie, Adriana Simicich, Tony Gades, and Balasundar Raju

Integrating 3D Geometry of Organ for Improving Medical Image Segmentation ...... 318 Jiawen Yao, Jinzheng Cai, Dong Yang, Daguang Xu, and Junzhou Huang

Estimating Reference Bony Shape Model for Personalized Surgical Reconstruction of Posttraumatic Facial Defects ...... 327 Deqiang Xiao, Li Wang, Hannah Deng, Kim-Han Thung, Jihua Zhu, Peng Yuan, Yriu L. Rodrigues, Leonel Perez Jr., Christopher E. Crecelius, Jaime Gateno, Tiansku Kuang, Steve G. F. Shen, Daeseung Kim, David M. Alfi, Pew-Thian Yap, James J. Xia, and Dinggang Shen

A New Approach of Predicting Facial Changes Following Orthognathic Surgery Using Realistic Lip Sliding Effect ...... 336 Daeseung Kim, Tianshu Kuang, Yriu L. Rodrigues, Jaime Gateno, Steve G. F. Shen, Xudong Wang, Han Deng, Peng Yuan, David M. Alfi, Michael A. K. Liebschner, and James J. Xia Contents – Part V xxxiii

An Automatic Approach to Reestablish Final Dental Occlusion for 1-Piece Maxillary Orthognathic Surgery ...... 345 Han Deng, Peng Yuan, Sonny Wong, Jaime Gateno, Fred A. Garrett, Randy K. Ellis, Jeryl D. English, Helder B. Jacob, Daeseung Kim, and James J. Xia

MIC Meets CAI

A Two-Stage Framework for Real-Time Guidewire Endpoint Localization ...... 357 Rui-Qi Li, Guibin Bian, Xiaohu Zhou, Xiaoliang Xie, ZhenLiang Ni, and Zengguang Hou

Investigating the Role of VR in a Simulation-Based Medical Planning System for Coronary Interventions ...... 366 Madhurima Vardhan, Harvey Shi, John Gounley, S. James Chen, Andrew Kahn, Jane Leopold, and Amanda Randles

Learned Full-Sampling Reconstruction...... 375 Weilin Cheng, Yu Wang, Ying Chi, Xuansong Xie, and Yuping Duan

A Deep Regression Model for Seed Localization in Prostate Brachytherapy...... 385 Yading Yuan, Ren-Dih Sheu, Luke Fu, and Yeh-Chi Lo

Model-Based Recommendations for Optimal Surgical Placement of Epiretinal Implants ...... 394 Michael Beyeler, Geoffrey M. Boynton, Ione Fine, and Ariel Rokem

Towards Multiple Instance Learning and Hermann Weyl’s Discrepancy for Robust Image-Guided Bronchoscopic Intervention ...... 403 Xiongbiao Luo, Hui-Qing Zeng, Yan-Ping Du, and Xiao Cheng

Learning Where to Look While Tracking Instruments in Robot-Assisted Surgery ...... 412 Mobarakol Islam, Yueyuan Li, and Hongliang Ren

Efficient Soft-Constrained Clustering for Group-Based Labeling ...... 421 Ryoma Bise, Kentaro Abe, Hideaki Hayashi, Kiyohito Tanaka, and Seiichi Uchida

Leveraging Other Datasets for Medical Imaging Classification: Evaluation of Transfer, Multi-task and Semi-supervised Learning ...... 431 Hong Shang, Zhongqian Sun, Wei Yang, Xinghui Fu, Han Zheng, Jia Chang, and Junzhou Huang xxxiv Contents – Part V

Incorporating Temporal Prior from Motion Flow for Instrument Segmentation in Minimally Invasive Surgery Video...... 440 Yueming Jin, Keyun Cheng, Qi Dou, and Pheng-Ann Heng

Hard Frame Detection and Online Mapping for Surgical Phase Recognition...... 449 Fangqiu Yi and Tingting Jiang

Automated Surgical Activity Recognition with One Labeled Sequence...... 458 Robert DiPietro and Gregory D. Hager

Using 3D Convolutional Neural Networks to Learn Spatiotemporal Features for Automatic Surgical Gesture Recognition in Video ...... 467 Isabel Funke, Sebastian Bodenstedt, Florian Oehme, Felix von Bechtolsheim, Jürgen Weitz, and Stefanie Speidel

Surgical Skill Assessment on In-Vivo Clinical Data via the Clearness of Operating Field...... 476 Daochang Liu, Tingting Jiang, Yizhou Wang, Rulin Miao, Fei Shan, and Ziyu Li

Graph Neural Network for Interpreting Task-fMRI Biomarkers ...... 485 Xiaoxiao Li, Nicha C. Dvornek, Yuan Zhou, Juntang Zhuang, Pamela Ventola, and James S. Duncan

Achieving Accurate Segmentation of Nasopharyngeal Carcinoma in MR Images Through Recurrent Attention ...... 494 Jia-bin Huang, Enhong Zhuo, Haojiang Li, Lizhi Liu, Hongmin Cai, and Yangming Ou

Brain Dynamics Through the Lens of Statistical Mechanics by Unifying Structure and Function...... 503 Igor Fortel, Mitchell Butler, Laura E. Korthauer, Liang Zhan, Olusola Ajilore, Ira Driscoll, Anastasios Sidiropoulos, Yanfu Zhang, Lei Guo, Heng Huang, Dan Schonfeld, and Alex Leow

Synthesis and Inpainting-Based MR-CT Registration for Image-Guided Thermal Ablation of Liver Tumors ...... 512 Dongming Wei, Sahar Ahmad, Jiayu Huo, Wen Peng, Yunhao Ge, Zhong Xue, Pew-Thian Yap, Wentao Li, Dinggang Shen, and Qian Wang

CFEA: Collaborative Feature Ensembling Adaptation for Domain Adaptation in Unsupervised Optic Disc and Cup Segmentation...... 521 Peng Liu, Bin Kong, Zhongyu Li, Shaoting Zhang, and Ruogu Fang Contents – Part V xxxv

Gastric Cancer Detection from Endoscopic Images Using Synthesis byGAN...... 530 Teppei Kanayama, Yusuke Kurose, Kiyohito Tanaka, Kento Aida, Shin’ichi Satoh, Masaru Kitsuregawa, and Tatsuya Harada

Deep Local-Global Refinement Network for Stent Analysis in IVOCT Images ...... 539 Yuyu Guo, Lei Bi, Ashnil Kumar, Yue Gao, Ruiyan Zhang, Dagan Feng, Qian Wang, and Jinman Kim

Generalized Non-rigid Point Set Registration with Hybrid Mixture Models Considering Anisotropic Positional Uncertainties ...... 547 Zhe Min, Li Liu, and Max Q.-H. Meng

A Mixed-Supervision Multilevel GAN Framework for Image Quality Enhancement...... 556 Uddeshya Upadhyay and Suyash P. Awate

Combined Learning for Similar Tasks with Domain-Switching Networks . . . . 565 Daniel Bug, Dennis Eschweiler, Qianyu Liu, Justus Schock, Leon Weninger, Friedrich Feuerhake, Julia Schüler, Johannes Stegmaier, and Dorit Merhof

Real-Time 3D Reconstruction of Colonoscopic Surfaces for Determining Missing Regions ...... 573 Ruibin Ma, Rui Wang, Stephen Pizer, Julian Rosenman, Sarah K. McGill, and Jan-Michael Frahm

Human Pose Estimation on Privacy-Preserving Low-Resolution Depth Images ...... 583 Vinkle Srivastav, Afshin Gangi, and Nicolas Padoy

A Mesh-Aware Ball-Pivoting Algorithm for Generating the Virtual Arachnoid Mater...... 592 Hirofumi Seo, Taichi Kin, and Takeo Igarashi

Attenuation Imaging with Pulse-Echo Ultrasound Based on an Acoustic Reflector ...... 601 Richard Rau, Ozan Unal, Dieter Schweizer, Valery Vishnevskiy, and Orcun Goksel

SWTV-ACE: Spatially Weighted Regularization Based Attenuation Coefficient Estimation Method for Hepatic Steatosis Detection ...... 610 Farah Deeba, Caitlin Schneider, Shahed Mohammed, Mohammad Honarvar, Edward Tam, Septimiu Salcudean, and Robert Rohling xxxvi Contents – Part V

Deep Learning-Based Universal Beamformer for Ultrasound Imaging ...... 619 Shujaat Khan, Jaeyoung Huh, and Jong Chul Ye

Towards Whole Placenta Segmentation at Late Gestation Using Multi-view Ultrasound Images ...... 628 Veronika A. Zimmer, Alberto Gomez, Emily Skelton, Nicolas Toussaint, Tong Zhang, Bishesh Khanal, Robert Wright, Yohan Noh, Alison Ho, Jacqueline Matthew, Joseph V. Hajnal, and Julia A. Schnabel

Single Shot Needle Tip Localization in 2D Ultrasound ...... 637 Cosmas Mwikirize, John L. Nosher, and Ilker Hacihaliloglu

Discriminative Correlation Filter Network for Robust Landmark Tracking in Ultrasound Guided Intervention ...... 646 Chunxu Shen, Jishuai He, Yibin Huang, and Jian Wu

Echocardiography Segmentation by Quality Translation Using Anatomically Constrained CycleGAN ...... 655 Mohammad H. Jafari, Zhibin Liao, Hany Girgis, Mehran Pesteie, Robert Rohling, Ken Gin, Terasa Tsang, and Purang Abolmaesumi

Matwo-CapsNet: A Multi-label Semantic Segmentation Capsules Network ...... 664 Savinien Bonheur, Darko Štern, Christian Payer, Michael Pienn, Horst Olschewski, and Martin Urschler

LumiPath – Towards Real-Time Physically-Based Rendering on Embedded Devices ...... 673 Laura Fink, Sing Chun Lee, Jie Ying Wu, Xingtong Liu, Tianyu Song, Yordanka Velikova, Marc Stamminger, Nassir Navab, and Mathias Unberath

An Integrated Multi-physics Finite Element Modeling Framework for Deep Brain Stimulation: Preliminary Study on Impact of Brain Shift on Neuronal Pathways ...... 682 Ma Luo, Paul S. Larson, Alastair J. Martin, Peter E. Konrad, and Michael I. Miga

Correction to: Investigating the Role of VR in a Simulation-Based Medical Planning System for Coronary Interventions ...... C1 Madhurima Vardhan, Harvey Shi, John Gounley, S. James Chen, Andrew Kahn, Jane Leopold, and Amanda Randles

Author Index ...... 691