CELA3B Antibody [ELTS3B-1] Cat. No.: 33-922

CELA3B Antibody [ELTS3B-1]

Specifications

HOST SPECIES: Mouse

SPECIES REACTIVITY: Human

A partial recombinant protein (aa 82-238) was used as the immunogen for the CELA3B IMMUNOGEN: antibody.

TESTED APPLICATIONS: ELISA, WB

ELISA: 2-4 ug/ml; order BSA free format for coating

APPLICATIONS: Western blot: 1-2 ug/ml

Optimal dilution of the CELA3B antibody should be determined by the researcher.

Properties

PURIFICATION: Protein G affinity chromatography

CLONALITY: Monoclonal

ISOTYPE: IgG1, kappa

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

October 1, 2021 1 https://www.prosci-inc.com/cela3b-antibody-elts3b-1-33-922.html BUFFER: PBS with 0.1 mg/ml BSA and 0.05% sodium azide

CONCENTRATION: 0.2 mg/mL

STORAGE CONDITIONS: Aliquot and Store at 2-8˚C. Avoid freez-thaw cycles.

Additional Info

OFFICIAL SYMBOL: CELA3B

Chymotrypsin-like family member 3B, Elastase IIIB, Elastase-3B, Protease E, ALTERNATE NAMES: CELA3B, ELA3B

GENE ID: 23436

USER NOTE: Optimal dilutions for each application to be determined by the researcher

Background and References

Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to . Humans have six which encode the structurally similar proteins: Elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other , 3B has little elastolytic activity. Like most of the human elastases, 3B is secreted from the as a and, like other BACKGROUND: serine proteases such as , and ; it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. It may also function in the intestinal transport and metabolism of cholesterol. Elastases 3A/B have been referred to as Protease E and as Elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays.

ANTIBODIES FOR RESEARCH USE ONLY.

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October 1, 2021 2 https://www.prosci-inc.com/cela3b-antibody-elts3b-1-33-922.html