DERMATOLOGY PRACTICAL & CONCEPTUAL www.derm101.com Obligate and facultative paraneoplastic dermatoses: an overview Stefano Caccavale1, Gabriella Brancaccio1, Marina Agozzino1, Paola Vitiello1, Roberto Alfano2, Giuseppe Argenziano1 1 Dermatology Unit, University of Campania Luigi Vanvitelli, Naples, Italy 2 Department of Anesthesiology, Surgery and Emergency, University of Campania Luigi Vanvitelli, Naples, Italy Key words: dermatological paraneoplastic syndromes, obligate paraneoplastic dermatoses, facultative paraneoplastic dermatoses, malignancy, oncological dermatology Citation: Caccavale S, Brancaccio G, Agozzino M, Vitiello P, Alfano R, Argenziano G. Obligate and facultative paraneoplastic dermatoses: an overview. Dermatol Pract Concept. 2018;8(3):191-197. DOI: https://doi.org/10.5826/dpc.0803a09 Received: January 15, 2018; Accepted: March 9, 2018; Published: July 31, 2018 Copyright: ©2018 Caccavale et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Funding: None. Competing interests: The authors have no conflicts of interest to disclose. All authors have contributed significantly to this publication. Corresponding author: Stefano Caccavale, MD, Dermatology Unit, University of Campania Luigi Vanvitelli, Via Sergio Pansini, 5, 80131 Naples, Italy. Email:
[email protected] ABSTRACT Dermatological paraneoplastic syndromes are a group of cutaneous diseases associated with malig- nancy, but not directly related to the primary tumor itself or to its metastases. It is of utmost impor- tance for the dermatologist to recognize the major cutaneous paraneoplastic syndromes to diagnose the underlying tumors that trigger them as early as possible. In this overview, skin conditions that are highly correlated with malignancy, whose recognition implies a mandatory investigation of internal cancer, are described.