WHSC2 (NELFA) (NM 005663) Human 3' UTR Clone Product Data

OriGene Technologies, Inc. 9620 Medical Center Drive, Ste 200 Rockville, MD 20850, US Phone: +1-888-267-4436 [email protected] EU: [email protected] CN: [email protected] Product datasheet for SC208008

WHSC2 (NELFA) (NM_005663) Human 3' UTR Clone Product data:

Product Type: 3' UTR Clones Product Name: WHSC2 (NELFA) (NM_005663) Human 3' UTR Clone Vector: pMirTarget (PS100062) Symbol: NELFA Synonyms: NELF-A; P/OKcl.15; WHSC2 ACCN: NM_005663 Insert Size: 626 bp Insert Sequence: >SC208008 3’UTR clone of NM_005663 The sequence shown below is from the reference sequence of NM_005663. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site

GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AAGTACAAGCCCATGACCAATGTGTCCTAGAACCACCTGCCTCACAGCTGGCCGTCACTTGTGGGGGTC CACGGGACGATGGCTTTGCCAGCTTAAAGTAACCGGATGGCGGACACCTGGCCCCCGAGGTCCCCCGGC CGCCGCCCTGCTGCTGACCCAGCCTGTTTTAAGTTCTGGATGCATTTCTCTGGGGTATTTGGGGCTTAT TTTTAAAATTTTAATATGGGTTCTTTTTTGTGTGATTTAAGACACTTTTTGGACTCAACGTTACATTTT TGAATGTAGTAAGTAAATTAACCAAAAAAGTTACAACTTCCTAATTTTAGTGACAGCTCTGCCTGTTAG ACTCTTACTTTTTAAAATCTTTTCTATTTTCCCTCGCTGGGGCAGTGCCCTCCTACCCCCAGGGTTGAG GGGACCAAGGTGGCACGGTGGTACTGGGGGTGCGGCAGGGACACCCGACCACACCAGAGCGTGGGAGAC GGTGGGCCTTGTCCCCTGCCTGTGCCTGCCTGGGAGTTTTGTATTCATCTTTTGTATAGTTGTGGACAT TTAAGACAGTCTTTGGGTACCTATTTTCATTGTAAAACTATCTGAACCATTAAAGTCGAGCTTTTCTAA AGAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG Restriction Sites: SgfI-MluI OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). RefSeq: NM_005663.5

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. View online » ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 1 / 2 WHSC2 (NELFA) (NM_005663) Human 3' UTR Clone – SC208008

Summary: This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation. [provided by RefSeq, Jul 2008] Locus ID: 7469 MW: 23.6