A Contribufion to the Control of Soil-Transmitted Helminth Infecfions
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a contribution to the control of soil-transmitted helminth infections in Latin America and the Caribbean Operational guidelines for the implementation of integrated deworming activities a contribution to the control of soil-transmitted helminth infections in Latin America and the Caribbean Washington, D.C. 2015 Also published in: Spanish (2015): Pautas operativas para la puesta en marcha de actividades integradas de desparasitación: contribución al control de las geohelmintiasis en América Latina y el Caribe. ISBN 978-92-75-31861-4 PAHO HQ Library Cataloguing-in-Publication Data ********************************************************************************* Pan American Health Organization. Operational Guidelines for the Implementation of Deworming Activities: A Contribution to the Control of Soil-Transmitted Helminth Infections in Latin America and the Caribbean. Washington, DC : PAHO, 2015. 1. Helminthiasis – epidemiology. 2. Helminthiasis – diagnosis. 3. Helminthiasis – transmission. 4. Neglected Diseases. 5. Parasitic Diseases. 6. Public Health. 7. Americas. I. Title. ISBN 978-92-75-11861-0 (NLM Classification: WC 800) The Pan American Health Organization welcomes requests for permission to reproduce or translate its publications, in part or in full. Applications and inquiries should be addressed to the Department of Communications, Pan American Health Organization, Washington, D.C., U.S.A. (www.paho.org/publications/copyright-forms). The Department of Communicable Diseases and Health Analysis, Unit of Neglected, Tropical, and Vector Diseases ([email protected]) will be glad to provide the latest information on any changes made to the text, plans for new editions, and reprints and translations already available. © Pan American Health Organization, 2015. All rights reserved. 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Contents Acknowledgments ...................................................................................................................................................................... v Acronyms ........................................................................................................................................................................................ vii Glossary ......................................................................................................................................................................................... ix Introduction ................................................................................................................................................................................. xi 1. OBJECTIVE OF THE OPERATIONAL GUIDELINES ....................................................................................................... 1 2. TARGET AUDIENCE OF THIS REPORT ........................................................................................................................... 2 3. BACKGROUND AND FRAME OF REFERENCE ............................................................................................................. 3 3.1. Soil-transmitted helminth infections as a public health problem ...................................................... 3 3.2. The burden of soil-transmitted helminth infections worldwide and in Latin America and the Caribbean ................................................................................................................................................... 4 3.3. Interventions for control of the soil-transmitted helminth infections ............................................. 6 3.4. Deworming as an integral component of control of soil-transmitted helminth infections ..... 8 3.5. Integrating deworming into other public health activities, strategies, and programs ............... 12 3.5.1. Opportunities for integrating deworming activities into other public health components or programs........................................................................................................................ 13 4. OPERATIONAL FRAMEWORK ........................................................................................................................................... 19 4.1 Steps for implementing deworming activities at the national and subnational level ................ 19 STEP 1: Conduct an epidemiological situation analysis of STH .......................................................... 19 STEP 2: Mount an advocacy effort to obtain political buy-in; identify and establish partnerships for implementation ................................................................................................................... 20 STEP 3: Draft and implement a plan integrated into public health components or programs ............................................................................................................................................................... 22 STEP 4: Monitoring, evaluation, and operations research ................................................................... 28 5. ANNEXES ................................................................................................................................................................................ 39 References ...................................................................................................................................................................................... 63 List of Tables .................................................................................................................. 10 Table 1.2. BenefitsDeworming of deworming, strategies based by type on prevalence of soil-transmitted helminths ........................... 11 Table 3. Antiparasitic dosages by drug and age group, complementary interventions, and adverse effects ........................................................................................................................................... 12 and programs in the countries ..................................................................................................................... 12 Table 4. Benefits of integrating deworming activities into existing public health strategies Table 5. Recommended characteristics of deworming activities .................................................................. 13 Table 6. Components and programs with potential for integrating deworming of preschool-age children (ages 12 to 59 months) .............................................................................. 14 Table 7. Components, programs, and platforms with potential for integrating deworming activities for school-age children (ages 5 to 14 years) ...................................................................... 17 Table 8. Ideal conditions of the components, platforms, and programs with potential to integrate deworming .................................................................................................................................. 18 Table 9. Steps for integrating deworming into other public health components or programs ......... 19 Table 10. Packages of STH control measures............................................................................................................. 25 Table 11. Category of indicators, use, and collection frequency ....................................................................... 31 Table 12. Process indicators ............................................................................................................................................. 32 Table 13. Performance indicators ................................................................................................................................... 34 Table 14. Impact indicators ............................................................................................................................................... 36 List of Figures Figure 1. Life cycle of soil-transmitted helminths................................................................................................... 3 Figure 2. Prevalence of soil-transmitted helminth infections according to available studies, Latin America and the Caribbean, 1998 to 2007. ................................................................................ 5 Figure 3. Graphic representation