YOUR GUIDE to CONTINUING Heart and Vascular Care at Asante Rogue Regional Medical Center Welcome | 1
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AHFS Pharmacologic-Therapeutic Classification System
AHFS Pharmacologic-Therapeutic Classification System Abacavir 48:24 - Mucolytic Agents - 382638 8:18.08.20 - HIV Nucleoside and Nucleotide Reverse Acitretin 84:92 - Skin and Mucous Membrane Agents, Abaloparatide 68:24.08 - Parathyroid Agents - 317036 Aclidinium Abatacept 12:08.08 - Antimuscarinics/Antispasmodics - 313022 92:36 - Disease-modifying Antirheumatic Drugs - Acrivastine 92:20 - Immunomodulatory Agents - 306003 4:08 - Second Generation Antihistamines - 394040 Abciximab 48:04.08 - Second Generation Antihistamines - 394040 20:12.18 - Platelet-aggregation Inhibitors - 395014 Acyclovir Abemaciclib 8:18.32 - Nucleosides and Nucleotides - 381045 10:00 - Antineoplastic Agents - 317058 84:04.06 - Antivirals - 381036 Abiraterone Adalimumab; -adaz 10:00 - Antineoplastic Agents - 311027 92:36 - Disease-modifying Antirheumatic Drugs - AbobotulinumtoxinA 56:92 - GI Drugs, Miscellaneous - 302046 92:20 - Immunomodulatory Agents - 302046 92:92 - Other Miscellaneous Therapeutic Agents - 12:20.92 - Skeletal Muscle Relaxants, Miscellaneous - Adapalene 84:92 - Skin and Mucous Membrane Agents, Acalabrutinib 10:00 - Antineoplastic Agents - 317059 Adefovir Acamprosate 8:18.32 - Nucleosides and Nucleotides - 302036 28:92 - Central Nervous System Agents, Adenosine 24:04.04.24 - Class IV Antiarrhythmics - 304010 Acarbose Adenovirus Vaccine Live Oral 68:20.02 - alpha-Glucosidase Inhibitors - 396015 80:12 - Vaccines - 315016 Acebutolol Ado-Trastuzumab 24:24 - beta-Adrenergic Blocking Agents - 387003 10:00 - Antineoplastic Agents - 313041 12:16.08.08 - Selective -
Everything's Coming up Dusty...Phenomenal!!
2010-07-27 The Archives of Let's Talk Dusty! - Ev… The Archives of Let's Talk Dusty! Home | Profile | Active Topics | Active Polls | Members | Search | FAQ Username: Password: Login Save Password Forgot your Password? All Forums Let's Talk Dusty! The Forum Forum Locked You Set My Dreams To Music Printer Friendly Everything's Coming Up Dusty........Phenomenal!! Author Topic Sue Posted - 10/07/2009 : 09:54:41 Little by little I know i shouldn't say this, but, 'Dusty In Memphis' is not my No.1 Dusty album, nor is it 'A Girl Called Dusty' or even 'See All Her Fac es'. The best of them all for me, is the phenomenal 'Everything's Coming Up Dusty', a real roller-c oaster ride! The way the whole thing is put together is sheer brillianc e. What do you think of it? Does it have the same effect on you? United Kingdom Favourite songs? Songwriters? Would love to hear your thoughts. 428 Posts Sue xx Brian Posted - 10/07/2009 : 11:28:15 Where am I going? Yes, it's my favourite too! A brilliant, brilliant album. Favourite tracks? in order:- Doodlin','I had a talk with my man' (the first time Dusty proved to me she could better the original), 'It was easier to hurt him',' La Bamba', 'Won't be long','If it don't work out','Oh no! not my baby','I've been wrong before','Long after tonight is all over','That's how heartaches are made','Who can I turn to?','I can't hear you', and bringing up the rear 'Packin' up' United Kingdom I remember at the time it was the most 'lavish' album cover ever issued 2058 Posts by a British rec ord c ompany - the gatefold sleeve etc , and it c ost more - 37/6d!!! Brian mssdusty Posted - 10/07/2009 : 11:34:36 I’ve got a good thing I HAD A TALK WITH MY MAN.......REALLY GETS TO ME...NICE....HAS EVERYTHING IN IT FOR ME M THE LOOK OF LOVE IS IN YOUR EYES! USA Watch my video with Dusty on YouTube! 5821 Posts streepalicious Posted - 10/07/2009 : 13:42:30 Little by little Ah, Ev'rythings Coming Up Dusty is my all time fave too! Every track is brilliant and just so much fun, and each song perfectly compliments the next. -
A Guiding Force
Arcadia University ScholarWorks@Arcadia Faculty Curated Undergraduate Works Undergraduate Research Winter 12-10-2020 A Guiding Force Jessica Palmer Follow this and additional works at: https://scholarworks.arcadia.edu/undergrad_works Part of the American Popular Culture Commons, Music Performance Commons, Other American Studies Commons, and the Other Music Commons Jessica T Palmer Dr. Buckley Bruce Springsteen and The American Dream 12/10/2020 Cover Page for My Research Paper A Guiding Force Abstract In this paper, I will be addressing the main factors which influenced Bruce Springsteen’s career and songwriting, specifically regarding interpersonal relationships the singer has had and how that is evident in his work thus far. I will be relating that concept to his latest album release, “Letter to You” by analyzing track by track and attempting to find that common thread of connection that seems to speak so well to him and his audience. Why? I chose this topic and album because throughout this course I have really enjoyed dissecting Springsteen’s work and relating it to a bigger picture. As I have progressed throughout this course, I have been able to elevate my writing and approach song analysis in a new, more refined way. I also felt as though choosing “Letter to You” would allow for me to make the most accurate interpretation of what Springsteen is trying to say in the current moment since it just got released a few months ago. Overall, I wanted to write about this because it allows for some creative freedom, a stream of consciousness and a continuation of the work I have been trying to perfect over the semester in this class. -
Health Plan Insights
Health Plan Insights January 2020 Updates from December 2019 800.361.4542 | envisionrx.com Confidential - Document has confidential information and may not be copied, published or distributed, in whole or in part, in any form or medium, without EnvisionRxOptions’ prior written consent. Recent FDA Approvals New Medications TRADE NAME DOSAGE FORM APPROVAL MANUFACTURER INDICATION(S) (generic name) STRENGTH DATE Avsola Amgen Inc. Injection, Biosimilar to Remicade. For the treatment December 6, 2019 (infliximab-axxq) 100 mg/20 mL of/reducing the signs and symptoms of: Crohn’s disease, pediatric Crohn’s disease, ulcerative colitis, rheumatoid arthritis in combination with methotrexate, psoriatic arthritis, and plaque psoriasis. Vyondys 53 Sarepta Intravenous Solution, For the treatment of Duchenne muscular December 12, (golodirsen) Therapeutics, Inc. 50 mg/mL dystrophy (DMD) in patients who have a 2019 confirmed mutation of the DMD gene that is amenable to exon 53 skipping. Padcev Astellas Injection, For the treatment of adult patients with locally December 18, (enfortumab 20 mg/vial and 30 advanced or metastatic urothelial cancer who 2019 vedotin-ejfv) mg/vial have previously received a programmed death receptor-1 (PD-1) or programmed death-ligand 1 (PD-L1) inhibitor, and a platinum-containing chemotherapy in the neoadjuvant/adjuvant, locally advanced or metastatic setting. Conjupri CSPC Ouyi Tablets, For use alone or in combination with other (levamlodipine) Pharmaceutical 1.25 mg, 2.5 mg, and antihypertensive agents for the treatment of December 19, Co., Ltd. 5 mg hypertension, to lower blood pressure. 2019 Caplyta Intra-Cellular Capsules, For the treatment of schizophrenia in adults. December 20, (lumateperone) Therapies, Inc. -
Insight ISSUE 1
ISSUE 1 IMMUNE CHECKPOINTS & insight IMMUNOTHERAPY RESEARCH Immune Checkpoints and Cancer Cancer immunotherapy seeks to use the many A better approach is to intervene when T cells components of the immune system to attack meet cancer cells, where TCR-mediated activation cancer cells. More specifically, immunotherapy initiates cell killing. Programmed death-1 (PD-1) is maximizes the effectiveness of components of a lymphocyte receptor that binds PD-L1 or PD-L2. the antigen-presentation and antigen-response When PD-L1 is expressed on cancer cells, it causes system, primarily dendritic cells and lymphocytes, PD-1 to negatively regulate TCR-mediated activation respectively. Ideally, this approach can offer more of T cells, limiting their cytotoxic activity. Several selective killing of cancer cells than other therapeutic antibodies have been developed to block the modalities, such as chemotherapy. ability of PD-L1 to interact with PD-1. Clinical trials using these antibodies to antagonize the PD-L1/PD-1 Immune checkpoint therapy is a form of cancer interaction have demonstrated tumor killing that is immunotherapy that centers on lymphocyte both specific and long-lasting.3,4 In May 2016, signaling, with a current focus on T cells. These the first PD-L1 inhibitor was approved by the cells can be activated to multiply, secrete cytokines, U.S. Food and Drug Administration for the and kill target cells with high selectivity. Activation treatment of bladder cancer. requires the T cell receptor (TCR) be stimulated by an antigen presented by the major histocompatibility Studies using antibodies to block the inhibitory complex (Ag/MHC). Selectivity and strength of checkpoint receptors CTLA-4 and PD-1 demonstrate activation are regulated by co-stimulatory or the feasibility of this type of immunotherapy. -
© Ferrata Storti Foundation
LETTERS TO THE EDITOR It was recently demonstrated in sickle cell mice that Impaired pulmonary endothelial barrier function in increased vascular permeability contributes to pulmonary sickle cell mice edema and the pathophysiology of ACS.8 Studies using Evans blue dye confirmed an increased permeability in Acute and chronic pulmonary complications leading to the sickle cell mouse lung, however, EC barrier function significant morbidity and mortality occur in persons with was not investigated. To gain additional insights into bar- sickle cell disease (SCD). One of the leading causes of rier function, we performed studies with cultured EC 1 death is acute chest syndrome (ACS), diagnosed by a from the lungs of the Townes knock-in sickle cell mouse 2 new infiltrate on chest x-ray often triggered by infection. (SS) and heterozygote (AS) littermates. Using endothe- The resulting low oxygen saturation leads to hemoglobin lial-specific CD31 conjugated Dynabeads, we isolated S polymerization, red blood cell sickling, vaso-occlusion mouse lung microvascular EC (MLMVEC) from SS 3 and hypoxia, the hallmark of ACS. Pulmonary endothe- (SS-MLMVEC) and AS (AS-MLMVEC) mice (Online lial cell (EC) barrier function is mainly regulated by the Supplementary Methods). The EC were grown as a opening and closing of tight junctions in the intercellular monolayer, and phase-contrast microscopy demonstrated space that controls the passage of macromolecules and the cobblestone structure (Figure 1A). They expressed cells across the vascular wall.4 The association of tight endothelial nitric oxide synthase and platelet adhesion junctions with the actin cytoskeleton is required for the molecule and take up acetylated low density lipoprotein dynamic regulation of junction opening and closure.5 (data not shown), characteristics consistent with the EC Under hypoxic and infection conditions, cell-cell junc- phenotype. -
What Should I Know About My Cardiac Nuclear Stress Test with Lexiscan® (Regadenoson) Injection?
What should I know about my cardiac nuclear stress test with Lexiscan® (regadenoson) injection? Use: Lexiscan (regadenoson) injection is a prescription drug given through an IV line that increases blood flow through the arteries of the heart during a cardiac nuclear stress test. Lexiscan is given to patients when they are unable to exercise adequately for a stress test. Important Safety Information: Lexiscan should not be given to patients who have certain abnormal heart rhythms unless they have a pacemaker. PLEASE SEE IMPORTANT SAFETY INFORMATION ON PAGE 16. PLEASE SEE FULL PRESCRIBING INFORMATION ON PAGES 22-25. Coronary artery disease What is coronary artery disease? The heart is a specialized muscle. Like other muscles in your body, it needs oxygen and nutrients. The coronary (heart) arteries deliver oxygen and nutrients to your heart so that it can effectively pump blood throughout your body. People with heart disease may have 1 or more coronary arteries that have become narrowed or clogged over time by fatty deposits (also called plaques). These can decrease blood flow to the heart. Page 2 is an illustration that shows you what a healthy artery looks like compared with an unhealthy artery. So less blood flow is bad, right? Exactly. Reduced blood flow may cause chest pain (angina), shortness of normal artery breath, and potentially a heart attack. Injured heart muscle can be permanently damaged if the coronary arteries stay blocked for too long. If there is a problem with your heart, it is important to find out about it as soon as possible. My doctor scheduled me for an MPI test. -
Rxoutlook® 1St Quarter 2019
® RxOutlook 1st Quarter 2020 optum.com/optumrx a RxOutlook 1st Quarter 2020 Orphan drugs continue to feature prominently in the drug development pipeline In 1983 the Orphan Drug Act was signed into law. Thirty seven years later, what was initially envisioned as a minor category of drugs has become a major part of the drug development pipeline. The Orphan Drug Act was passed by the United States Congress in 1983 in order to spur drug development for rare conditions with high unmet need. The legislation provided financial incentives to manufacturers if they could demonstrate that the target population for their drug consisted of fewer than 200,000 persons in the United States, or that there was no reasonable expectation that commercial sales would be sufficient to recoup the developmental costs associated with the drug. These “Orphan Drug” approvals have become increasingly common over the last two decades. In 2000, two of the 27 (7%) new drugs approved by the FDA had Orphan Designation, whereas in 2019, 20 of the 48 new drugs (42%) approved by the FDA had Orphan Designation. Since the passage of the Orphan Drug Act, 37 years ago, additional regulations and FDA designations have been implemented in an attempt to further expedite drug development for certain serious and life threatening conditions. Drugs with a Fast Track designation can use Phase 2 clinical trials to support FDA approval. Drugs with Breakthrough Therapy designation can use alternative clinical trial designs instead of the traditional randomized, double-blind, placebo-controlled trial. Additionally, drugs may be approved via the Accelerated Approval pathway using surrogate endpoints in clinical trials rather than clinical outcomes. -
The Heart of Dialogue Is a Simple but Profound Capacity to Listen
A publication of the INTERCOMMUNITY PEACE & JUSTICE CENTER NO. 110 / SPRING 2016 The heart of dialogue is a simple but profound This means listening not only to oth- Emerson once joked that ninety-five ers but also to ourselves and our own percent of what goes on in our minds capacity to listen. reactions. Recently a manager in a pro- is none of our business! We often pay gram I was leading told me, “You know, great attention to what goes on in us, By William Isaacs I have always prepared myself to speak. when what is actually required is a But I have never prepared myself to lis- kind of disciplined self-forgetting. istening requires we not only hear ten.” This is, I have found, a common This does not have to be difficult. It is the words, but also embrace, ac- condition. For listening, a subject we of- within the reach of each of us. cept, and gradually let go of our ten take for granted, is actually very hard To do this you do not have to retreat Lown inner clamoring. As we explore it, to do, and we are rarely prepared for it. to a monastery or to be converted to we discover that listening is an expansive To listen is to develop an inner si- some new belief. You do, though, have activity. It gives us a way to perceive more lence. This is not a fa- to do some deliberate work to cultivate directly the ways we participate in the miliar habit for settings inside yourself and with oth- world around us. -
Table of Contents
1 •••I I Table of Contents Freebies! 3 Rock 55 New Spring Titles 3 R&B it Rap * Dance 59 Women's Spirituality * New Age 12 Gospel 60 Recovery 24 Blues 61 Women's Music *• Feminist Music 25 Jazz 62 Comedy 37 Classical 63 Ladyslipper Top 40 37 Spoken 65 African 38 Babyslipper Catalog 66 Arabic * Middle Eastern 39 "Mehn's Music' 70 Asian 39 Videos 72 Celtic * British Isles 40 Kids'Videos 76 European 43 Songbooks, Posters 77 Latin American _ 43 Jewelry, Books 78 Native American 44 Cards, T-Shirts 80 Jewish 46 Ordering Information 84 Reggae 47 Donor Discount Club 84 Country 48 Order Blank 85 Folk * Traditional 49 Artist Index 86 Art exhibit at Horace Williams House spurs bride to change reception plans By Jennifer Brett FROM OUR "CONTROVERSIAL- SUffWriter COVER ARTIST, When Julie Wyne became engaged, she and her fiance planned to hold (heir SUDIE RAKUSIN wedding reception at the historic Horace Williams House on Rosemary Street. The Sabbats Series Notecards sOk But a controversial art exhibit dis A spectacular set of 8 color notecards^^ played in the house prompted Wyne to reproductions of original oil paintings by Sudie change her plans and move the Feb. IS Rakusin. Each personifies one Sabbat and holds the reception to the Siena Hotel. symbols, phase of the moon, the feeling of the season, The exhibit, by Hillsborough artist what is growing and being harvested...against a Sudie Rakusin, includes paintings of background color of the corresponding chakra. The 8 scantily clad and bare-breasted women. Sabbats are Winter Solstice, Candelmas, Spring "I have no problem with the gallery Equinox, Beltane/May Eve, Summer Solstice, showing the paintings," Wyne told The Lammas, Autumn Equinox, and Hallomas. -
Anger, Part 3
Getting to the Heart of Conflict: Anger, Part 3 By David Powlison onflict concerns all of us: you, me, the people sustained by diplomats, mediators, counselors, and with whom we live and work. This is the third other well-intended people are gifts of common grace. Cin a series of articles on anger problems,1 but But God’s special grace is even more profoundly this time we’ll broaden the subject beyond anger, per about peacemaking. Warlike humans surrender to se. Anger problems are only one strand in the larger Christ. He made peace once for all between us and problem of interpersonal conflict. Yes, angry actions God; He continues to make peace, teaching us to do and emotions often seize center stage in conflicts, but the same with each other; and He will make peace, an extended family of reactions each play their part in finally and forever. the real-life drama: fear, hurt, self-pity, gossip, avoid- This article will weave together several things. ance, escapist comfort-seeking, lying, manipulation, First, we will look at the Scriptures, and several key even perverse joy. truths the Lord teaches us about war and peace. This To understand and solve anger problems, we must involves asking the questions, “When God looks at deal with conflict in all its forms. People fight with your conflicts, what does He see?,” and “How does each other and with God; sinful anger is but one of the God make right what is wrong?” The Scriptures reveal weapons. We fight our neighbors and our Ruler, both God’s gaze, the criteria by which He continually eval- by nature and by nurture. -
EANM Procedural Guidelines for Radionuclide Myocardial Perfusion Imaging with SPECT and SPECT/CT
EANM procedural guidelines for radionuclide myocardial perfusion imaging with SPECT and SPECT/CT Chair of writing committee (responsible for the coordination of the overall process): Hein J. Verberne and Birger Hesse Authors: Hein J. Verberne, Wanda Acampa, Constantinos Anagnostopoulos, Jim Ballinger, Frank Bengel, Pieter De Bondt, Ronny R. Buechel, Alberto Cuocolo, Berthe L.F. van Eck-Smit, Albert Flotats, Marcus Hacker, Cecilia Hindorf, Philip A. Kaufmann, Oliver Lindner, Michael Ljungberg, Markus Lonsdale, Alain Manrique, David Minarik, Arthur J.H.A. Scholte, Riemer H.J.A. Slart, Elin Trägårdh, Tim C. de Wit, Birger Hesse Correspondence to: H.J. Verberne, MD PhD Department of Nuclear Medicine, F2-238 Academic Medical Center University of Amsterdam Meibergdreef 9 1105 AZ Amsterdam The Netherlands Tel: *31-20-5669111, pager 58 436 Fax: *31-20-5669092 E-mail: [email protected] 1 Author affiliations: H.J. Verberne Department of Nuclear Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands Tel: +31 20 566 9111, pager 58 436 Fax: +31 20 566 9092 E-mail: [email protected] W. Acampa Institute of Biostructures and Bioimaging, National Council of Research, Naples, Italy Tel: +39 0812203409 Fax: +39 0815457081 E-mail: [email protected] C. Anagnostopoulos Center for Experimental surgery, Clinical and Translational Research, Biomedical research foundation, Academy of Athens, Greece Tel: +30 210 65 97 126 or +30 210 65 97 067 Fax: +30 210 65 97 502 E-mail: [email protected] J. Ballinger Department of Nuclear Medicine, Guy's Hospital - Guy's & St Thomas' Trust Foundation, London, United Kingdom Tel: +44 207 188 5521 Fax: +44 207 188 4094 E-mail: [email protected] F.