BOOK REVIEWS

Cellular grams, and drawings are well chosen, of Disease and the tables contain sufficient detail , to demonstrate critical points. This is Vectors – 2nd ed. 2nd ed. particularly true for chapters 4–6, which describe the surface William C. Marquardt, editor properties, how pathogenic Pascale Cossart, Patrice Boquet, adhere to and enter the host cell, and Elsevier Academic Press, Staffan Normark, ultimately how the induces and , editors Burlington, Massachusetts various types of cell signaling. The Second Edition final chapters focus on new methods ASM Press, Washington, DC ISBN: 0-12-473276-3 of identifying virulence genes and the Pages: 785, Price US $99.95 ISBN: 1-55581-302-X use of nonvertebrate hosts, such as Pages: 593, Price: US $119.95 plants and insects, to model mam- This edition is a massive, 7-section, malian . The field of cellular microbiology 57-chapter medical entomology refer- This book has only a few draw- ence text. The chapters are written by is relatively new and incorporates backs. For example, the first 2 intro- aspects of microbiology and host cel- 72 experts from around the world and ductory chapters are too detailed. In provide an understanding of disease lular biology. The first edition of this subsequent chapters, the emphasis is text, published in 2000, was novel and vectors on a broad front, including placed on bacterial ; only 1 biologic requirements of vectors, epi- well received. In general, this new chapter is dedicated to viruses and edition is also well written and demiology, , genet- none to eukaryotic pathogens (only ics, principles of control, and insecti- includes many of the most important the introductory paragraphs in chapter recent advances in the field (e.g., cide resistance. The text consistently 1) or to nonpathogenic microorgan- emphasizes molecular biologic microarrays and genome sequencing). isms of any kind. The text deals almost exclusively with approaches to these topics. This volume will be an important This book begins by discussing the host cell responses elicited by interac- addition to the resources available to tions with pathogens. The editors are vectors themselves, with chapters on students and researchers in general mites, ticks, true bugs, lice, fleas, top researchers in the field of bacteri- or microbiology. Perhaps al cellular microbiology, and they mosquitoes, and various dipterans Internet interactive companion pro- such as tsetse flies and sand flies. Line have brought together many new grams and accompanying CDs would investigators to write chapters in their drawings and black-and-white pic- be useful with future editions. tures abound. The number of color areas of expertise. Because the field is moving so quick- The book’s first 2 chapters contain photos is limited; those in the kissing ly, the authors might consider more bug/bed bug chapter and the flea topical background information. frequent updates. These chapters thoroughly cover chapter are especially beautiful. Subsequent sections delve into the many of the basic concepts in molec- Frederick Quinn* ular cell biology and introduce all of physiologic and genetic basis of vec- *University of Georgia, Athens, Georgia, tor biology. The final 2 sections con- the various pathogens (bacterial, viral, USA and eukaryotic) currently being exam- cern controlling insects and acarines ined in the popular literature. The Address for correspondence: Frederick Quinn, and special (laboratory) methods organization of the subsequent chap- Department of Infectious Diseases, College of associated with vectors. The last sec- ters typically alternates between top- Veterinary Medicine, University of Georgia, tion, which deals with laboratory ics in cell biology and bacterial patho- Athens, GA 30602, USA; fax: 706-542-5771; methods, is like a giant appendix in genesis. For example, chapter 11 email: [email protected] which updates are given for the care, describes assembly of the cellular maintenance, and experimental infec- , while chapter 12 tion of various disease vectors, The opinions expressed by authors con- describes the mechanisms used by including notes on handling, housing, pathogenic bacteria to manipulate the tributing to this journal do not necessari- rearing facilities, containment, and cytoskeleton. Subsequent chapters ly reflect the opinions of the Centers for safety issues. provide good coverage of bacterial Disease Control and Prevention or the One of the most helpful chapters for this reviewer was the one entitled, systems, , and their institutions with which the authors are “Systematic Relationships among interactions with the host immune affiliated. system. Generally, the figures, dia- Disease Vectors,” which defines

1330 Emerging Infectious Diseases • www.cdc.gov/eid • Vol. 11, No. 8, August 2005 BOOK REVIEWS molecular terminology Tuberculosis and The book is divided into 3 sec- and explains how phylogenetic rela- tions, each consisting of multiple tionships among species are inferred the Tubercle chapters on various subjects. The first from molecular data. I wish every tra- Bacillus section focuses on clinical aspects of ditional taxonomist and systematist the disease, including the global would read this chapter. impact of TB, clinical and epidemio- This book contains a few mis- Steward T. Cole, logic features, as well as diagnosis spellings (e.g., the chapter title in the Kathleen Davis Eisenach, and treatment. The second section Table of Contents, Chapter 46), but no David N. McMurray, deals with the bacteriology of M. major errors. Its only weakness seems and William R. Jacobs Jr, editors tuberculosis, with chapters devoted to to be one of disunity. The title doesn’t molecular , , cell match the book’s content, and the text ASM Press, Washington, DC wall structure and synthesis, and is so comprehensive that it seems ISBN: 1-55581-295-3 . The third section details unfocused. There are chapters on Pages: 584; Price: US $125.95 the host-pathogen interaction, cover- chemical and genetic control of vec- ing topics such as the intracellular sur- tors, cell culture, and even research Mycobacterial infections, includ- vival of M. tuberculosis, host immune safeguards for transgenic mosquitoes. ing tuberculosis (TB) and leprosy, are response, animal models, and vaccine How these fit under the title biology bacterial diseases of global impor- development. of vectors was difficult to discern. tance. An estimated 2 billion people The book accurately reflects cur- Perhaps in future editions, the chief are infected with Mycobacterium rent knowledge of TB and recent editor could split the book into sever- tuberculosis. Control of TB is compli- research efforts and progresses to the al separate volumes, each with a more cated by its ease of transmission, dif- control of the disease. The book flows appropriate title. ficulty in administering the long- smoothly from chapter to chapter. Nevertheless, this book is an indis- course chemotherapy regimens, and Each chapter is clearly written and pensable reference and a wonderful subsequent appearance of multidrug- appropriately referenced. The book treasure trove of information about resistant strains (MDR-TB). This situ- focuses primarily on M. tuberculosis; medical entomology. Its only flaws ation is made even worse by the dead- research performed on other are organizational, not factual. The ly combination of coinfections of HIV mycobacterial species is not discussed chief editor, section editors, and and M. tuberculosis. New approaches or only briefly mentioned. authors are to be congratulated on this to the control of TB are urgently need- Nevertheless, at 584 pages, this book scholarly work. ed, including development of short- is easily read and is a useful reference term antimicrobial regimens to mini- for clinicians and basic scientists, Jerome Goddard*† mize the appearance of drug resist- including students, laboratory super- *Mississippi Department of Health, ance, new drugs to treat MDR-TB visors, and senior scientists. Jackson, Mississippi, USA; and †University patients, and new vaccines with of Mississippi Medical Center, Jackson, greater efficacy than BCG. Jun Liu* Mississippi, USA Tuberculosis and the Tubercle *University of Toronto, Toronto, Ontario, Bacillus has many contributors; chap- Canada Address for correspondence: Jerome Goddard, ters are provided by experts in many Mississippi Department of Health, 570 East areas of TB research to bring together Address for correspondence: Jun Liu, Woodrow Wilson, Jackson, MS 39215, USA; a comprehensive update of research Department of Medical Genetics and fax 601-576-7632; email: jgoddard@msdh. development in the past decade. The Microbiology, Medical Sciences Building, state.ms.us publication of this book is necessary #4382A, 1 King’s College Circle, Toronto, All material published in Emerging Infectious and timely, considering the current Ontario M5S 1A8, Canada; fax: 416-978-6885; Diseases is in the public domain and may be urgencies and growing interests of email: [email protected] used and reprinted without special permission; proper citation, however, is required. investigators from various fields.

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