wellcomegenomecampus.org/connectingscience Wellcome Genome Campus CB10 1RQ CB10 Connecting Science Hinxton, Cambridgeshire Hinxton,

Review Annual 2017/18 CONNECTING SCIENCE 022 Democratising Snapshot: May 2017 to April 2018 Catalysing collaboration Global ambitions in twelve months Science Connecting and engagement A hub of knowledge, learning, Wellcome Genome Campus: Contents 57 Credits touch in Get Publications networks and partners Our are we Who Conferences Scientific and Courses Advanced of years Thirty culture changing Campus, changing times, Changing thinking for spaces Creating Gallery Genome the in world our Exploring to listen remembering communication: Science policy balance agender – Implementing success and sweat Blood, together genomes Decoding counsellors genetic for event global First partners scientific together Bringing Colombia in hunting Worm needs training tailoring by impact global Increasing DNA? your on say your had you Have 56 48 – 49 46 – 47 40 – 41 38 – 39 50 – 51 22 – 23 24 – 26 36 – 37 27 – 32 20 – 21 04 – 05 12 – 13 0–11 10 – 1 14 – 16 54 55 57 INTRODUCTION R’S DIRECTO professionalism and seemingly bottomless energy of our our of energy bottomless seemingly and professionalism the things: to many testament is out, week and in week quality, high such at activities, of diversity incredible this to deliver able is Science Connecting that fact The languages. different multiple into translated been has that sharing data to genomic attitudes about asurvey from responses analysing or Ghana, in technologies genomic on course training practical aweek-long running next, the groups interest patient and day one teachers school secondary from Campus to the visits leading , cell organising and delivering a cutting-edge conference on single be might Science Connecting week, atypical During colleagues. and institutions with collaboration constant involves do we everything and globe, the spans it families; their and to patients staff NHS scientists, research to schools primary from audiences reaching complex, deceptively also is do we that work The healthcare. and research both in practice into put and developed continually being technologies new with ever-changing, and complex is itself science The complexity. considerable is words simple those Behind society. and health research, on impact its and science genomic to explore everyone to enable simple: is Science Connecting of mission The

Director, Connecting Science Connecting Director, Rayner Julian Dr started. getting just are we genomics, like -just to come year the about excited more even year, but past the over work our of proud We are sciences. of universal most this democratising and change that in everyone to involving committed are we Science Connecting At individuals. and aspecies as both it, in place our and world, the of understanding our about things many so changing is Genomics do. we that all in have we excitement the of asense you give Review Annual this in highlighted stories the of some that I hope year. every directly with engage we people of thousands of tens the for experiences career-changing or life- into translates often energy and support this that know and things, those of all for thankful very personally Iam Wellcome. of encouragement and support financial the and collaborators, and partners many our of support and commitment the team,

03 ANNUAL REVIEW 2017/18 CONNECTING SCIENCE 04 2,582 2,582 languages into which languages been translated participants surveys have have surveys CONNECTING SCIENCE CONNECTING 11 Advanced Courses and ScientificConferences

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05 ANNUAL REVIEW 2017/18 Global ambitions Genomic science has the potential to affect us all, no matter where in the world we are. We seek to inspire new thinking around both its applications and its implications, and ensure this discussion is heard. We strive to support global health and research, making sure the best people have access to the best The importance of public engagement and training, and to gather opinions gathering public opinion discussed by @adthoro at ethics and consent session at #humancellatlas general meeting. Nice to from across the world. see @genomethics #yourdnayoursay shown as an example

@WGCengage

Want to know more about our @ACSCevents activities in low and middle-income countries? We have a fascinating Q&A with Overseas Courses Development Officer, Alice Matimba @alicepn on our website

@ConnectingSci

We won! We’re honoured to be awarded in the comics category @ISNTD_Press #ISNTDfestival. A big thank you to all of our #WormHunters. Remember the hunt, and beating the #whipworm continues!

@WormHunters GLOBAL AMBITIONS 10 culturally adapted the survey for their own countries. countries. own their for survey the adapted culturally and translated have who counsellors, genetic and scientists social mostly collaborators, international of anetwork with working by possible made been has task This opinion. their to give world the across from people allowing languages different multiple into translated been has Your Say DNA Your scale, aglobal on attitudes To explore language! English to the apply only words these course of But DNA. and genes genomics, as such before, encountered have not may they subjects discussing when to people meaningful are which words to find metaphors to use Anna allowed have Genome the Socialising as such projects previous from Findings University of Bologna. Niemiec, Emilia and University, Uppsala Howard, Heidi Dr collaborators, her and Anna, by scripted and created all were which films short nine around based is survey The Task Team. Values Participant GA4GH’s with together Middleton, Anna Dr Research, Ethics and Society of Head our by designed was survey novel this (GA4GH), Health and Genomics for Alliance Global the by Supported before! scale this on happened never has DNA their in contained information to the happens what on opinion their for people asking Surprisingly, sharing. data genomic towards attitudes public gathering survey online aglobal is project 2016, the in launched First Research Ethics and Society Head Middleton, — Anna issue.” the on voice public aclear having without is shared data how about made being policy there’s of arisk moment usglobally. for the At gap evidence is ahuge “There out. to find aims project Your Say Your DNA, The data’? ‘big into incorporated being scan, iris an or afingerprint than personal more is which blueprint, entire their data, genomic their about feel people do how But world. the over all from researchers and clinicians scientists, by accessed be can it where databases online in stored then and people, millions – of ideally thousands – by donated is data health other and DNA if however, successful, be only can process This treatment. and diagnoses, medical to health, relating questions many to unlock potential the has research Genetic HAVE YOU YOUR HAD SAY ON YOUR DNA?

Have your say: www.yourdnayoursay.org say: your Have sharing. its and data genomic addressing to policy voice public global agenuinely offer will findings their that confident are they Hindi, and Zulu Chinese, Mandarin as such languages in Your Say Your DNA of versions new to launch continue team her and Anna As data. of donation free a from profits making companies pharmaceutical about concerned most were why. People and data to their access get would who about suspicions with yes, said sample the of half only research, for DNA their donate would if they asked When children. onto passed is and relatives, to their them links it that way the in is it that say they information, medical of sorts to other different as DNA see if they asked when However, genomics. and genetics DNA, of concepts the with unfamiliar mostly are Australia Canada, USA, UK, in publics representative that been has participants speaking English- 10,000 approximately from findings initial The 20 countries. over from participants 20,000 over had has and Arabic, and Icelandic Japanese, Russian, including 11 languages, in active is Your Say Today, Your DNA adaptation.” cultural of importance and complexity the highlight really this like Projects languages? certain for persona pertinent most the is Which feminine. or -masculine agender have should survey the in references person third the whether about to think had also We have time. first the for mean concepts the what to describe having are we exists currently genomics for language no Where fascinating! been has process translation “The says, Anna As challenges: unique own its with come has work The languages into which been translated surveys have have surveys 11

public voice on the issue. without having clear a about how data is shared risk being made of policy the moment there’s a gap for us globally. At There is ahuge evidence

11 SOCIETY + ETHICS RESEARCH GLOBAL AMBITIONS 12 NEEDS NEEDS TRAINING TAILORING BY IMPACT GLOBAL INCREASING interests and needs. and interests developing and organising courses tailored to regional by gap this to bridge seek Courses Overseas resources. and tools advanced these of uptake to the community research the in a barrier creating thereby capacity, lack America South and Asia Africa, across countries Yet many disease. and health of understanding our increasing for opportunities immense created have technologies genomic new and advances Scientific diagnostics. clinical and research in use for analysis data sequence and surveillance, genomic microbiology, clinical biology, molecular informatics-based courses applying techniques in and laboratory developed they time, Over methods. computational using genomes pathogen and human to analyse how teaching on focused initially Courses Overseas (LMICs), countries middle-income and low- in professionals health and scientists research biomedical at primarily aimed and 2006, in Started team. (ACSC) Conferences Scientific and Courses Advanced the by delivered activities training and learning the of part akey been long have Courses Overseas participants in 2017 Overseas Courses Courses Overseas 136

— Alice Matimba, ACSC Matimba, — Alice some of these challenges.” in tackling role important an play Courses Overseas the mentorship, expert and funding in accessing scientists by faced barriers the understanding By Caribbean. the and America Latin and Asia, Africa, in LMICs in most education and research science genomic for in capacity gaps massive are “There Courses. Overseas of impact and diversity reach, geographical activities, the expand to apipeline to develop efforts well-established these upon in 2017,building is Officer Development Courses Overseas first its as ACSC joined who Matimba, Alice Dr interventions. health public and research, health genomics, across development capacity for opportunities and technology, in advances on regularly to consult panel expert an up setting also are team The needs. local identify to help scientists regional leading with to working groups, research or societies regional subject-specific in individuals targeting surveys conducting from this, to achieve approaches of anumber adopted have team ACSC The of regions varying Fully understand the needs ONE STEP regional participants is just as important. as just is participants regional to accessible made and delivered be will course a how of considerations practical The equation. the of part only is need strategic identifying But impact. potential its and sustainability, will incorporate regional collaboration and it how also but activities, course’s the only not outlining Committee Steering ACSC to the aproposal submit instructors prospective of a team identified, been has topic acourse Once them. address may which actions other and courses training the on decide and to assess easier is it demand, greatest of areas the for base evidence astrong to develop groundwork this laid Having need the match to training the Identify STEP TWO

delivered annually to eleven per year by 2020. by year per to eleven annually delivered Courses Overseas of number the to increase plan They interactions. microbiome-host and discovery drug topics, genomics human of variety developing regionally-tailored courses for a also are partners selected and team ACSC the recommendations from various research leaders, account into taking and gaps identified Having Introducing more courses skills and impact Widening FOUR STEP and delivery. organisation course of improvement continuous guides which expectations and needs their about information useful provide also Participants satisfied”. “Very feeling 80% over with Courses, Overseas for satisfaction of level ahigh indicates Post-course feedback from participants clearly 2017 Ghana, Genetics, Experimental Malaria — Participant, support.” of kind this without course in the participated have in full. not Icould accommodation and fees my supported bursary “The bursaries. accommodation and travel by supported also are participants and free are Courses Overseas attending, from applicants suitable most the prevent not do barriers financial that To ensure reach. international their broadening America, South and Africa, courses will also subsequently rotate across Asia, The respectively. Kenya, and Vietnam in year this later place take will which Resistance, Antimicrobial and Genomics Viral in courses new of development to the led approach 2017 this In details are incorporated in teaching materials. who contextual ensure regions, the targeted and UK the from experts, of teams collaborative of consist largely teams instructor The regions. these in scientists up-coming talented with expertise their to share time valuable their up to give prepared are who professionals health and scientists renowned from commitment the is Courses Overseas of success to Key the support. administration and academic local and facilities appropriate with venues suitable locating as well as materials, training of development the and meetings instructor facilitate team ACSC The deck! on hands All THREE STEP

[bursary] support. [bursary] I could not have participated in the course without this Uruguay, 2016 Databases, Parasite with Working — Participant, directly.” my institution benefit that proposals new towrite me allowed has This toaccess. impossible almost was otherwise which training with in touch toget and scope, my towiden me helped course “The too. communities extended their but attending those just not benefits training this that confirms consistently which feedback, participant long-term by up backed are methods these that encouraging is It review. under constantly is needs regional for catering and to evaluating approach their so team, ACSC the for priority a key is countries middle-income low- and in deliver they training the of reach and impact the Maximising 2017 Vietnam, Genomes, Pathogen with Working — Participant, skills future.” the for developing and week the aims for our on toreflect ustime gave and helpful Train“The Trainer very were the workshops institutions. home to their return they when others teach and learning to approach their to enhance skills pedagogical with participants provides This Officer. Education ACSC’s element, developed and piloted by Dr Pamela Black, Trainer Train the the is addition valuable Another Learning and sharing 2017 Rica, Costa Pathogens, Bacterial of Surveillance Epidemiological and Genomics — Participant, course.” the on welearned what applying for and networking for opportunity excellent is an It participants. other the with project aresearch do to funding was the course the about part best “The impact. global with and level aregional at a team, as relevance health public of projects implementing and networking in experience gained participants genome sequencing techniques. By collaborating, whole and methods epidemiological applying by Salmonella enterica in resistance antimicrobial and diversity genomic to study grants small awarded were Pathogens Bacterial of Surveillance Epidemiological and Genomics from Participants scenario. a real-life to course week-long the from obtained skills and knowledge the to apply participants for opportunity an providing courses, into projects research of integration the for apilot launched 2017 ACSC In projects funding Seed and Klebsiella and pneumoniae

13 ADVANCED COURSES + SCIENTIFIC CONFERENCES GLOBAL AMBITIONS 14 COLOMBIA IN HUNTING WORM and how they were contributing to María’s research. to María’s contributing were they how and avoided, be could infection future how transmitted, is parasite the how explaining while infections, parasitic gut with children school to treat aimed project the activities, engagement and collection sample Combining 50%. is children in rate infection whipworm the where Colombia, of coast Caribbean the on town a Ciénaga, in place took project The programme. engagement schools and collection egg whipworm integrated an to produce team, Engagement Public the with project Hunters Worm the developed María assemble! Hunters Worm The further. parasite the investigate can she that so children infected from eggs whipworm to collect aprogramme to establish Colombia in Antioquia of University the at collaborators with working been has María treatment. after reinfection repeated of acycle in caught often are they sanitation, or water to clean access without populations for and, eggs whipworm by contaminated been has that water or food ingesting through spread is disease The America. South and Africa Asia, of parts many across affected are people million 700 estimated An children. infected of development physical and intellectual the affects also potentially and diarrhoea, and pain abdominal causing gut the invades worm parasitic This (Trichuris trichiura). whipworm human the studying is she where group, Genomics Parasite Institute’s Sanger Wellcome the in Fellow NC3Rs an is Duque-Correa María Dr International for Society Neglected Tropical Diseases Festival 2018 in March! The Worm Hunters comic has won the comic showcase award at the the at award showcase comic the won has comic Hunters Worm The — Laura Olivares Boldú, Public Engagement Public Boldú, Olivares — Laura appealing.” and attractive be would that style like talked all and them, in a like them looked that comic in the characters weused so children in Colombia, the to familiar tofeel illustrations and characters language, the We wanted prevented. and treated be can it how and infection the about more tounderstanding diagnosed, being unwell and feeling from ajourney children on the takes comic The scared. tobe them want didn’t “We other parasites: or whipworm with infected being about feel might children the how and comic, the of elements the about carefully to think had team the and Laura samples. their use would she how and project research her describing themselves, María, her research collaborators and the school children featuring strip acomic includes also It learning. reinforce to activities and whipworm human the about information of acombination contains and Boldú, Olivares Laura Engagement’s Public by designed was book comic The future. the in infection whipworm to avoid them helping and study, María’s for samples providing them of likelihood the increasing families, their with learnt they what share to them enabled it addition, In them. from samples stool needed María why understand and worm’s biology the to explore children the helped approach This infections. of spread the prevent can washing hand how to explore gel hand aglitter used and eggs, their and whipworms at look to ever!) time first (for the microscopes used children The classroom. the in activities hands-on complementary, alongside used be would that and school in through work could children the that book acomic to develop decided team The study. her in participation encourage and research, María’s with Ciénaga in community the engage to effectively required was approaches of amixture that clear became soon It projects. education and engagement the Public Engagement team’s experience of developing with this combining Ciénaga; in situation the explore to Antioquia, of University the at collaborators her of knowledge the and background, Colombian María’s of advantage took project Hunters Worm The with. working be will you people the of understanding a full to gain important is it effective, to be project engagement public any For stories science to tell book A comic

Colombia. from samples the in collected they eggs the from whipworms harvesting are they where Institute, Sanger Wellcome the at back are they now research the with happening is what sharing to continue team the enabled also It’s practice. research their and them benefit could approach this how in interested researchers parasite experiences with a wider audience, including other their to share media social and videos blogs, used have team Hunters Worm the impact local this beyond And Duque-Correa — María back.” be wewould when also asking and samples the with todo going wewere what about curious very were children The laboratories. or scientists about heard never had they if even well received was very idea this I think worms. without happily live all so children can vaccines and medicines new todevelop us and infect worms the how tounderstand important so are samples their why children tothe toexplain wetried comic, the “Through lives. their affect may science how and does, scientist a what in interest sparking in also but whipworm of terms in only not Ciénaga, in community the on impact asubstantial had have Hunters Worm the that clear It’s Institute Sanger Wellcome Duque-Correa, — María friends.” and family their of rest the involving and learning tocontinue return they and, importantly, samples stool the horrible!), taste bringing (which can medicine the taken, drinking being toblood agree they sick, getting about experiences their tosharing open more are they Moreover, too. research the of part are they feel they comic, the with todo wetried is what which themselves, identify can they in which children in asimple way to information the delivering when opinion, my “In research. their of success the on impact adirect have also but with, work they communities the benefit only not can activities engagement public of programme intense an how collaborators to Maria’s demonstrated has This 90%. around was project this in participation contrast, In 50%. of rate participation a had have community same the in run programmes deworming Previous benefits. other of anumber had also but part, took who pupils and researchers the for experience engaging afun, in resulted only not project Hunters Worm to the approach blended The field the in Out Twitter and Facebook via @WormHunters on Worm project Hunters the of Follow continuation the www.wormhunters.org website project the on documented are Worm Hunters of generation next the inspiring and treatments, deworming delivering collection, sample undertaking of experiences her and 2018 in February toCiénaga María’s journey interventions. health better ultimately and data, research better to leading research, in participation public improve also but community that benefit only not can research scientific with children school engaging how demonstrated has projects Hunters Worm The project. this of part to be delighted been We have with, but also have the success ofthe success their work [scientists] they An intenseAn programme research. communities the benefit a direct impact on activities not can only of public engagement

15 PUBLIC ENGAGEMENT Catalysing collaboration We champion collaboration and conversation across borders, disciplines and communities. We are uniquely placed to bring together relevant understanding and expertise, to deliver a diverse range of activities with genuine impact. Our partnerships and networks are amongst our Excited that avatars worked well in our training course in Jan. Great collaboration most valuable assets. #genomicmedicine with @Cambridge_ICE @emblebi @sangerinstitute @ConnectingSci. Also supporting #WomenInScience with gender policy http://bit.ly/2oKv0GN and grants http://bit.ly/2CSYsiH

@ACSCevents

What an amazing world congress. So wonderful to share with some of the amazing Aussie gc [genetic counselling] community. Thank you to the organisers #wcgc17

@Lucinda_Freeman

What an amazing day #genomedecoders @WGCengage @sangerinstitute @ResearchInSch Fantastic @TaptonSchool1 @Fran_Gale & also on @BBCWorldatOne

@ProfBeckyParker CATALYSING COLLABORATION 20 PARTNERS PARTNERS SCIENTIFIC TOGETHER BRINGING whole genome sequencing for diagnostic purposes. purposes. diagnostic for sequencing genome whole of use increasing the reflecting places, available 18 the for world the across from applications 60 over with huge, was course the for demand expected, As Research Virus for Centre Glasgow of MRC-University Lecturer, Senior Clinical and instructor course lead Thomson, Emma — Dr gap.” that tobridge starting is, Conferences Scientific and Courses Advanced by co-ordinated expertly course, this and healthcare to routine laboratory research the from transition for need unmet is alarge There pathways. in clinically-validated it implemented have who those and research for routinely it use who those from experience practical delivers course new This expertise. set-up bioinformatic and laboratory specialised requires that is amethod it but setting, healthcare in the pathogens viral unrecognised previously and known both todiagnose ability our generation sequencing“Next will soon revolutionise infections. viral identifying and detecting for sequencing genome whole of use the in training -based and laboratory both offered London, College University and Research, Virus for Centre Glasgow of MRC-University the England, Health Public team, ACSC the between acollaboration through created course, Virology Clinical and Genomics The control. infection and investigation, transmission diagnostics, for genomics real-time enabling hours, in undertaken be can microbes of years. Now whole genome sequencing ofhundreds many for infections viral of management and diagnosis have been appliedmethods to the detection dependent Virology. Viral genome sequencing and sequence- Clinical and Genomics courses, newest ACSC’s of one in part Wellcome to take Campus Genome the at arrived year, virologists 18 this of February In atopic. on thinking latest the and techniques research cutting-edge to both exposed are events their at participants that ensure team the fields, their in experts with working By events. training and learning innovative and new create to professionals clinical and research leading together bringing of record track awell-established have (ACSC) Conferences Scientific and Courses Advanced the expertise of all its partners to deliver training courses courses training to deliver partners its all of expertise the leverages approach their that confident are team ACSC The Singapore. and Argentina as Kenya, afield far as from travelling trainees with overall, represented were Ten countries UK. the outside from them of half with group, the of diversity the to reflect designed were scenarios different two The Africa. and UK the in outbreaks viral of scenarios clinical around based projects group to training their to apply opportunity the with concluded week The interpretation. data and analysis bioinformatic to on moving before technologies, and approaches different using patients Cinfected hepatitis from material genetic sequenced and prepared Participants countries. middle-income low- and in or Campus the on held whether genomics, pathogen in courses its of to all relation in ACSC by seen trend general the of part is demand of level This The course on Genomics Virus Research, together with collaborators from from the MRC-University MRC-University the from Singapore and Vietnam. lopment of anadditional and Clinical Virology has has Clinical Virology and of Glasgow Centre for instructors with course directly to led the deve- collaborators, and alumni! and collaborators, partners, of networks its with endeavour this in share to delighted are Conferences Scientific and Courses and healthcare professionals around the world. Advanced scientists for training needed much to provide continue and overseas, and UK the in running currently events training genomics parasite and bacterial of programme existing the complement will courses virology new These Vietnam. City, Minh Chi Ho in Unit, Research Clinical University Oxford the with partnership in September, in place take will course the countries, middle-income and low- in those for Course Overseas an as designed Specifically together with collaborators from Singapore and Vietnam. Research, Virus for Centre Glasgow of MRC-University the from instructors with Genomics and Bioinformatics Viral on course additional an of development to the led directly has Virology Clinical and Genomics on course first This impact. awider have and demand existing meet both that

21 ADVANCED COURSES + SCIENTIFIC CONFERENCES CATALYSING COLLABORATION 22 Take alook at #WCGC17 shared their thoughts on Twitter! Delegates enthusiastically Anna had become... Science colleagues! Connecting her with address could she that achallenge saw also She experiences. and learning to share world-wide leaders nursing and counsellor genetic for aforum of lack the of aware Increasingly mainstream medicine. mainstream in genetics of communication the and counselling genetic guides that evidence the explored practice, ... The Congress... The speakers... 15 and Counsellors. Nurses Genetic of Association UK the of Vice-Chair the now also is and NHS the within counsellor agenetic as practice of years many had has Research, Ethics and Society of Head Middleton, Anna Dr truly exciting and innovative events. events. innovative and exciting truly deliver can programme the within held expertise and skills the combining how collaborative success, an example of a also was it Science Connecting For society. wider and patients publics, communicate genomic information to to how understand to better wanting community aglobal counsellors; genetic designed ...successfully delivered a programme from both researchers and clinical clinical and researchers both from by genetic counsellors for for counsellors genetic by EVENT FOR GENETIC FOR EVENT FIRST GLOBAL GLOBAL FIRST

COUNSELLORS

Anna approaches Advanced Courses and Scientific Conferences (ACSC), who constantly seek to identify new areas of scientific interest and unmet demand. by the Operational Team. Operational the by event the of delivery the Manages Conference Centre Conference and Events Organiser, Tirelli Sophia delegate experience. the to deliver Laura and Sophia with Work Operational Team Conference Centre

National Human Genome Research Institute, USA Institute, Research Genome Human National Biesecker Professor Barbara Head of Society and Ethics Research Ethics and Society of Head Middleton Anna Dr countries. 24 from different 220 delegates together 2017, bringing 4-6 October on Campus Genome Wellcome the at held was Counselling Genetic on Congress World first The as well as administrative support. administrative as well as Provides speaker, delegate and venue logistics Conference and Events Manager, ACSC Hubbard Laura Advanced Courses ScientificAdvanced and Conferences counselling process. This is presented at the ACSC Steering Committee for funding approval. funding for Committee Steering ACSC the at presented is This process. counselling ACSC Scientific Programme Manager Programme Scientific ACSC Treasa Creavin Dr They put together a Scientific Programme Committee of international experts and develop develop and experts international of Committee Programme aScientific together put They a meeting proposal for an event based around the patient journey through the genetic genetic the through journey patient the around based event an for proposal a meeting

the conference topics in detail, invite speakers, speakers, invite detail, in topics conference the develop Treasa and Committee Programme The and identify external financial support to to support financial external identify and provide bursaries for delegates. Programme and King’s London College Patch D Committee Scientific Scientific r Christiner

23 CONNECTING SCIENCE CATALYSING COLLABORATION 24 schools have approached Genome Decoders. For some some For Decoders. Genome approached have schools ways different the is interesting particularly been has What WormBase parasite resource. public the through community scientific wider the with shared and hosted be ultimately will and scientists Campus by reviewed are annotations These genome. whipworm the of 10% around annotated have students the that estimate we writing of time the At computers. own their on UK the around from activities annotation out to carry able now are students tool, curation browser Apollo available publicly the on EBI and Institute Sanger Wellcome the at scientists and team Engagement Public the by developed training received Having activities. school after and clubs science various of part as genome T. the on trichiura working been have schools 50 over from students far So in. come Decoders Genome the where is which process, time-consuming and intensive alabour- is annotation manual expect, might you As targets. drug or vaccine new find potentially and cycle infection the in involved genes key understand better to world the around researchers by used be can that genome afully-curated in results eventually annotation of standard’ ‘gold This be. might function their what predict and genes of different location the find definitively to used is evidence this of All make. they proteins the at looking and organisms, similar from sequences to gene data the comparing agene, of boundaries the indicate that markers the to find tools bioinformatics with sequences DNA analysing person areal involves This annotation. genome manual called aprocess through is them, within variations the and them, identify to accurately way best the but genome, their in location their and genes predict can programs Computer altogether. task another is means all it what understanding generated, been has data this although but, sequenced been recently has genome whipworm the in contained DNA the All areas. many for expensive too or ineffective often are treatments existing and available vaccine no currently is there but affected, communities the on impact a chronic has infection year. Whipworm each people million 700 around in malnutrition and pain abdominal diarrhoea, causes which worm aparasitic is known, commonly T. trichiura trichiura Trichuris the of analysis to the to contribute UK the across schools in based Decoders Genome enthusiastic a 1,000 around recruited has project this Engagement, Public Campus Genome Wellcome by coordinated and (EBI), Institute,Sanger EMBL-European Institute Bioinformatics Wellcome Schools, in Research for Institute the between the Decoders project Genome does. A collaboration what exactly that’s but scientists, research established out to help asked are formers sixth that often not It’s genome. , or the human whipworm as it’s more it’s as whipworm human the , or DECODING GENOMES

TOGETHER

— Teacher, Oxford High school High — Teacher, Oxford involvement!” further for queue the in first to be like is -I’d it hope much Ivery -and is along-term project this If agenome. annotating and Apollo using about myself learned I’ve that everything also loved I’ve count!),last but the 75 at than (more students the from commitment and enthusiasm the by overwhelmed been life. I’ve professional in my done ever Ihave things engrossing wholly and challenging fun, interesting, exciting, most the of is one “It year. this achieved work great the to continue students of cohort to anew handed is project the where involved, schools the within alegacy be will there that anticipated is it years, two over spanning initiative an to be likely is this As annotations. the out to carry students of teams managing and directing project, the for champions the are students the schools other for but process; the through students the guided and lead the taken has ateacher where initiative, ateacher-led been has this development. career about is it as world, to the difference a positive making about much as is Decoder aGenome to become students for motivation the often scientists, many like But choices. career future their influencing perhaps first-hand, extended opportunity to experience the research process an gained have students part taking By research. scientific of nature distributed often and collaborative the of example aperfect is Decoders Genome kind, its of project annotation genome mass-participation first the As Lead, Public Engagement Development Education Gale, — Francesca research.” genomic with public and schools engaging projects research participatory many of first the be will hopefully Decoders Genome and area, in this plans ambitious has Campus Our work. informatics technically-demanding out tocarry scientists alongside working of challenge tothe rise can students opportunities, and training materials appropriate given that, show Decoders like Genome of. Projects capable of sequence! sections to interpret hard discussing scientists and students between exchanges email the to see interesting been has It issues. technical any report or data complex deciphering with help request can teachers and students where hotline, email an created team WormBase the issues these of some To address cohort. the across contributions of assessment robust the and involved schools many the between work of allocation the teachers, and students of upskilling schools, in issues access internet include These schools. in project annotation genome alarge-scale implementing of challenges practical and technical the on aspotlight placed has Decoders Genome “We can often underestimate what young people are are people young what underestimate often can “We

ever done in my professional life. have I things engrossing wholly fun, interesting, challenging and It is one of the most exciting,

25 PUBLIC ENGAGEMENT This [#HumanEvol17] Snapshot has been such a wonderful event - and combining a cutting edge conference from @ACSCevents with a packed public engagement evening from @WGCengage is every @ConnectingSci dream come true....

@rayner_julian

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2017 JULY NOVEMBER 2018 APRIL

Proteomics Bioinformatics course Human Evolution: Fossils, Ancient and Genomics of Brain Disorders conference Modern Genomes conference MAY Genomics and Epidemiological Surveillance of SEPTEMBER JANUARY Malaria Experimental Genetics course Bacterial Pathogens course in Costa Rica Working with Pathogen Genomes in Thailand Applied Bioinformatics and Public Health Animal Genetics and Diseases conference course in Vietnam Healthy Aging: From Molecules to Microbiology conference Conference Centre hosts ON Helix 2017 Organisms conference Orkney International Science Festival Conference Centre hosts Biodata Fungal Pathogen Genomics course World Congress 2017 Fundamentals of Clinical Genomics course Molecular Approaches to Clinical Music of Life Malaria Experimental Genetics course takes Microbiology course in South Africa Your DNA Your Say survey launched place for the first time in Ghana Overseas Course seed in Iceland project begins funding pilot project Genome Decoders FEBRUARY initiated in Costa Rica Engage Week Your DNA Your Say gets underway Café Sci Cambridge launched survey launched in on Wellcome Genomic Practice for Genetic Counsellors Genome Campus Russian AUGUST OCTOBER Human and Vertebrate Genomics: Bioinformatics Worm Hunters team Tools and Resources in South Africa Next Generation Sequencing arrive in Colombia JUNE Wayne McGregor researches Autobiography Bioinformatics course DECEMBER on Campus Translational Bioinformatics conference Working with Parasite Database First festive family film screening in Resources course in Malawi Conference Centre Genome Gallery – Hidden Lives exhibition opens Derivation and Culture of hiPSCs course MARCH Public Engagement Masterclass course ACSC-policy statement Cambridge Science Festival on germline editing First ever World Single Cell Biology conference published Congress on Target Validation Conference Centre Event Conference Centre hosts Human Cell Atlas Genetic Counselling Using Genomics General Meeting Management service and Informatics Worm Hunters comic wins International Society for Neglected Tropical Diseases Festival award opens for business conference

Genome Gallery — Genomic Expressions exhibition opens

Learning

Research

Engagement

Space Wonderful insight into the human side of genetic testing. Genomics will bring these dilemmas to many many more of us, often with less binary outcomes and even harder choices. @ConnectingSci is committed to engaging everyone in this complex subject, learning together.

@rayner_julian Democratising genomics Genomics is about us, and we believe it should be for everyone. Our work aims to spark new and interesting conversations, and places equality at its fore.

Congratulations to Treasa Creavin @ACSCevents for receiving the @wellcomegenomecampus Best Practice Award for supporting #WomenInScience with gender policy! http://bit.ly/2oKv0GN @ConnectingSci @sangerinstitute @TADG_Creavin #WomensDay

@ACSCevents

Paper written with @Genomethics now up, ready for open peer review: Genetics in the 21st Century - reflecting upon some of the ways that #Genomic data may touch us as patients, consumers and citizens. #Sequencing #PrecisionMedicine on @F1000Research

@TheSarcasticOwl

The ‘hidden lives’ exhibit at the wellcome genome campus is great. my kiddo has gone 3x. we also love the trees on the wall behind. Hidden Lives exhibition @marakat visitor contribution card DEMOCRATISING GENOMICS 36 SUCCESS - IMPLEMENTINGSUCCESS - implicit bias than of teaching quality of measure abetter are evaluations of type these that to suggest some leading counterparts, male their than lower rated are lecturers or teachers female that shown than those with female names female with those than hired to be likely more and highly more rated were names male CVs with identical that shown has research Recent life? to family conducive not position academic to apermanent promotion and progress for timeline the is Or academia? in ‘culture’ organisational aspecific of because research to academic attracted less women Are complex. and many are research academic leave women why reasons The level. professorial senior, more the at research academic in females fewer are there where but sciences, biomedical the in level PhD and undergraduate at equally represented are women and men where asituation describes academia, in well-known pipeline’, ‘leaky year. 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Several studies have have studies . Several a gender balance policy for Advanced Courses and Courses Advanced for policy balance a gender shares her perspective on developing and applying and developing on perspective her shares Scientific Programme Manager, Dr Programme Creavin, Treasa Scientific 2 . POLICY POLICY Scientific Conferences. 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37 ADVANCED COURSES + SCIENTIFIC CONFERENCES DEMOCRATISING GENOMICS 38 the concept of dialogue ofthe concept dialogue this that allows us to take Listening to people’s meaningful practice. meaningful rhetoricbeyond into and and their passions. It is concerns, their interests interests their concerns, TO LISTENTO REMEMBERING COMMUNICATION: SCIENCE that demonstrates the value of thinking about science, science, about thinking of value the demonstrates that research to explore was to start me for place A second science. about enough interested not or science, about enough positive not science, about enough knowing not as viewed are people often So deficits. their by science in interested not are who people characterising avoiding of communication science in challenge to awell-known relates This about. enthusiastic and in, interested are know, they what by positively, people viewing of effectiveness the demonstrates that research was First start. Icould places some were there challenge, asignificant was this While uninterested. the engaging by data this get only I could and data, got Ihad until uninterested the to engage how out find I couldn’t situation: 22 acatch in somewhat me put This data. Ineeded such as and question empirical an is this because Mostly topic. adifficult quite to be out turns this me’. hindsight In ‘for as general) in science (and genetics see don’t who people engage how to out to find Iwanted words, other In ingenetics? interested not are question: following the to explore out set initially research My How do we engage people with genetics who who genetics with people we engage do How

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39 SOCIETY + ETHICS RESEARCH DEMOCRATISING GENOMICS 40 GENOME GALLERY GENOME WORLD IN THE EXPLORING OUR “If my genome has information to predict my future” my topredict information has genome my “If height?” average are family my tall so Iam when “Why 47)” (I do? have chromosome extra my does “What out… to like find I’d here. place takes that science the to, relate and upon, reflect visitors our how about learning interesting provided also but exhibition the of richness to the added contributions These self. of sense or traits physical about statements personal as categorised were 42% these of collected, 124 the responses Of be?” it would what DNA, your from thing one out find could you “If question to the to respond visitors invited exhibition The Anglo-Saxons. the from ancestry its of athird about derives England of East the of population the that revealed samples modern-day of to hundreds DNA this Comparing nearby. found remains other five with along site, own our from excavated skeletons the of five of genomes the sequenced scientists Campus inhabitants. Anglo-Saxon to tools flint these from time of passage the charted exhibition The hunter-gatherers. were ancestors our when atime from dating blades, flint 5,000 were discovered objects earliest The artefacts. archaeological alongside Campus, the at excavated skeletons were display On public. the and community Campus our both –for science genomic with connecting and sharing in exhibitions of potential the demonstrating programming, our in a step-change was Lives Hidden scientists, Campus and archaeologists with collaboration in Developed making! the in years of thousands exhibition an 2017 opened we June In 2017) -December (June discovery of astory Lives: Hidden plans. future its outlines and exhibitions, successful most gallery’s the on reflects team, Engagement Public the within Curator Exhibition Gilmore, Becky Here, science. exploring themes from Wellcome Campus Genome exhibitions with delegates, Centre Conference and public, the of members visiting to engage aspace as Centre Conference the in situated is Gallery Genome The

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Public visitors to Hidden Lives; The average dwell time for an Open Saturday visit Open an x 4.5 more visits than previous exhibitions exhibitions previous 1,500 1,500 2hrs 2hrs

fascinating reading their answers. We have built on our our on built We have answers. their reading fascinating been it’s and question same to the to respond visitors inviting also We are journey. engagement public their starting us with worked previously not have who staff from to involvement leading call, open an as staged exhibition first the is Expressions Genomic visitors. with responses these to share wonderful been has it and ways, candid and creative unique, in question the approached all They scientists. senior and developers, software administrators, assistants, lab workforce: our across from responses creative sixteen features It toyou?” mean genomics does “What question to the to respond community Campus to the call open an on centred exhibition Expressions – an Genomic opened we 2018 February In disease. acertain developing of likelihood our or chin, family funny that eyes, mother’s my it: realising without even often, about talk we that asubject also is It all. us connects that asubject is genomics therefore and 99.5% are identical, genomes our humans As 2018) –June (February Genomic Expressions — fascinating” are research genome of possibilities and findings the archaeologist amateur and “As ahistorian Open Saturday visitor Saturday Open

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41 PUBLIC ENGAGEMENT Wellcome Genome Campus A hub of knowledge, learning, and engagement We are open and accessible to all, sharing knowledge, resources and ideas. We are committed to making our Campus a leader in the field of professional learning and public engagement with genomics, extending the reach Great to see us feature on @BBCLookEast and impact of the research which last night during an interview for the @humancellatlas meeting currently taking place in the conference centre. takes place here.

@WGCConfCentre

Did you know our programme is turning 30 this year? To celebrate we’re awarding 30 free places on our upcoming 2018 courses and conferences at the Wellcome Genome Campus!

@ACSCevents

Off to Comberton Village College today to talk about #WomenInScience #sciencejobs #malaria to years 7-13, with lots of aids from The Wellcome Genome Campus public engagement team! @WGCengage

@love_kitkat

Yesterday we welcomed back @Connect_EB to enrol a new group of #STEMAmbassadors. We now have 70 Ambassadors from @sangerinstitute @embi @wellcomegenome @ConnectingSci to lead #STEM engagement with young people!

@WGCengage A HUB OF KNOWLEDGE, LEARNING, AND ENGAGEMENT 46 event is spectacularly difficult. The exceptional quality of quality exceptional The difficult. is spectacularly event asuccessful delivering venue, the at facilities and staff the of support the have clients Unless is fantastic. which event, our about comments positive many so received I’ve conference. annual Partner Healthcare our hosting professionalism class first your for team Centre Conference Campus Genome Wellcome the and you Ithank “May participants. remote of involvement the facilitate and events, and meetings many of live-streaming the allowing adopted, been also have technologies visual audio- New in-between!). everything (and submissions to abstract speakers managing from organisers, to conference service standalone acompletely providing operation, of year afull almost enjoyed now has example, for Service, Management Event The guests. their support to ways new deliver to constantly strive therefore team The easy. not is ones new attracting and clients existing keeping environment, venue competitive Cambridge’s in But organisers. meeting and delegates attract that spaces, spectacular its with together resources, and services Centre’s Conference the of quality the is It Cambridge. of University the from departments numerous and Kymab, Illumina, UK, Research Cancer as such clients external of retention and business repeat the by evidenced also is Campus the outside data large-scale and genetics genomics, in working those with relationship strong Their meetings. Institute Sanger and dinners, programme symposia, retreats, industry and EMBL-EBI events hosts training regularly They communities: research science life wider and Campus Genome Wellcome the both for venue avaluable is Centre Conference The basis. adaily on delivers it projects of variety the on thrives Centre Conference the exhibition, Lives Hidden the of part as remains skeletal of display the during residents oldest Campus’ the of two for home the becoming or skills, modelling mathematical their developing fortnight intensive an after to relax looking researchers accommodating counsellors, genetic of meeting global ever first the hosting are they Whether Science. Connecting by delivered and coordinated organised, are that events and activities diverse the of many for hub physical the is Centre Conference Campus Genome Wellcome The CREATING SPACESCREATING FOR THINKING FOR continues to rise year-on-year. year-on-year. to rise continues which business in increase the to manage team Events and Sales size the of the increased has and efficiencies to improving aview with processes operational reviewing been has Centre Conference the year last the Over Atlas Cell Human Manager, Project Macharia, — Angela meeting.” our of success tothe crucial was this that acknowledge and meeting the of organisation the regarding attendees meeting the from reports glowing received We have meeting. the at 270 the of delegates hosting totheir through usasclients with interactions their from ranging was outstanding, team entire the by provided service The 2018. in March meeting Atlas Cell Human international the of coordination and planning in the was involved team Service Management Event “The for networking, learning and collaboration. environment optimal the providing by science genomic of understanding the progress helping in plays individual each role the to explain taken is Time team. Events and Sales the with working staff contract many the with relationships building into invested time significant the is this Behind feedback. organiser and delegate positive of level high aconsistently receives Centre Conference The 2017 Practice, WPA Healthcare Organiser, — Event you.” with working apleasure been has really It it. during team floor and office front the and event, the before guidance and patience all for your you us; for thank easier it made team Centre Conference the Conference Centre Wellcome Genome Campus Manager, Prior, Business — Linda clients.” external our and Campus wider the Science, Connecting of work the support asthey team dedicated this lead to proud Iam thinking. in their innovative all else above and proactive flexible, be to is required everyone therefore and changing constantly are needs, event with along industry, meetings and conference The delegates. their and clients our for service aseamless todeliver tirelessly work team the todelivery, From enquiry roles. of range adiverse across individuals professional truly many alongside to work privileged been Ihave years, of a number for Centre Conference Campus Genome Wellcome the at team the up “Heading

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47 CONFERENCE CENTRE A HUB OF KNOWLEDGE, LEARNING, AND ENGAGEMENT 48 researching the molecular basis of disorders of calcium calcium of disorders of basis molecular the researching Oxford of University the at Medicine of Professor May the is Thakker Rajesh and disease, brain neurodegenerative on working Antwerp, of University the at Genetics Molecular of Professor is Broeckhoven Van Christine now? participants course first those of some are Where cutting-edge. the at remains it to ensure changing constantly is programme the and technology and methods genomic in changes fast-paced the by superseded been have events early most But popular. very still is and 2001 in started – Informatics Genome – conference first our 2016, and until 29 years for ran and Biology, Systems and Genomics into Functional evolved course first The technologies. cell single and genomics viral as such topics in programmes two the between synergies from born were conferences and courses New ACSC. to form 1999) (established Programme Meetings Trust Wellcome the with joined Courses Advanced 2009 In 2005. in initiated were UK the in genomics in professionals healthcare for courses specialist and countries, income middle- and low- in genomics in capacity-building at aimed Courses Overseas the included initiatives New rapidly. expanded and 1998 in Campus Genome Wellcome to the moved programme the so and required, were facilities training permanent that apparent became it schools summer holding of years several After Jeffries. Alec and Ed Southern Professors including speakers with Frischauf, Anna-Maria and Davies Kay Professors were instructors expert The Trust. Wellcome the by funded Hospital, Thomas’ St and Guy’s at school asummer at Genetics Human in Methods Related DNA PCR) and electrophoresis gel field (pulse cutting-edge about to learn wanting 12 participants with 1988 in out started (ACSC) programme The Advanced Courses and ScientificConferences careers. build helping as well as disease, of diagnosis and research of acceleration to the contributing impact, real has programme the that demonstrates delegates from Feedback America. Latin and Asia Africa, in 1,493 courses at another and Campus, Genome Wellcome the at events our attended have countries different 130 over from professions healthcare and scientists 38,859 inception its Since Conferences! Scientific and Courses Advanced of anniversary 30th the marks year The knowledge in genomics. sharing through diagnostics and research Accelerating ADVANCED COURSES COURSES ADVANCED THIRTY YEARS OF AND SCIENTIFIC SCIENTIFIC AND CONFERENCES FutureLearn this April. April. this FutureLearn on –opened Resistance Antimicrobial and Outbreaks counselling. The first course BacterialGenomes:– Disease genetic in one and genomics, pathogen in courses online of aseries with reach international our extend to continue will 2018 for initiative learning online A new 2021. by events face-to-face our through professionals healthcare and scientists 20,000 another to reach aim and further even programme the expanding are we Currently medicine to healthcare professionals within the NHS. genomic in training to deliver England, Education Health and Institute, Sanger EMBL-EBI, Wellcome the Cambridge, of University the as such partners local with work We also interests. scientific mutual on building Genetics, Nature and Laboratories, Harbour Spring Cold Laboratory, Biology Molecular European the as such partners with held are conferences our of Some needs. training regional address to Organisation, Health American Pan the and H3Africa as such institutes, and organisations international with developed been have partnerships years, 30 last the Over ScientificConferences and Courses Advanced Head, Twells, — Rebecca world.”the across careers scientific developing and diagnostics research, on is having programme the impact the and years, 30 past the over programme the developing into put has team my work hard the of proud very am “I genomics. of field the in leaders of generation next the creating collaborations, important form and knowledge to share minds great together bringing as well as disease, of diagnosis improve accelerate their research, healthcare professionals tools to to skills the scientists talented giving highly-productive, and intense are events Our 259 conferences. and courses 374 held have we then Since career”. my in impact major “a having as course the remembers (1996). still He Genetics Human in published were school summer the at made they libraries linking the and (2005), Investigation Clinical of Journal the in published was electrophoresis gel field pulsed on produced data that notes Thakker Professor school.” summer of type this to initiate inspiration the had Morgan Michael that great was it and tutors fantastic were Frischauf Anna-Maria and Davies Kay libraries. linking and jumping and electrophoresis gel field pulsed about lot a learned I and one first the was it as well very meeting the remember “I recalls, Thakker Professor homeostasis.

Professor Thakker has helped us to identify Christine Van Broekhoven, Anna-Maria Frischauf, Frischauf, Anna-Maria Broekhoven, Van Christine to us identify helped has Thakker Professor , Michael Morgan, Pelin Faik, David Bentley, and Kevin Gatter. If you spot yourself in in yourself spot you If Gatter. Kevin and Bentley, David Faik, Pelin Morgan, Michael Davies, Kay First ever Advanced Course participants in 1988 this photo please let us know! us let please photo this

49 ADVANCED COURSES + SCIENTIFIC CONFERENCES A HUB OF KNOWLEDGE, LEARNING, AND ENGAGEMENT 50 CULTURE CHANGING CAMPUS, CHANGING TIMES, CHANGING Connecting Science Prizes for Public Engagement. Engagement. Public for Prizes Science Connecting inaugural the and Fund, Enabling anew programme, training acomprehensive were highlighted initiatives the Among 2017. November in Week’ ‘Engage Campus ever first the at these to spotlight We chose engagement. public towards change culture to support initiatives of anumber launched already we’ve term, long the into and high set are sights our although and, Campus our across happening discovery and research the as same fast-paced, is journey Our and external audiences. Campus our to both meaningful and relevant are which ways in effort engagement our to expand capacity collective our underpins to participate staff for conditions the Creating mission. engagement public our of ownership to share possible as community Campus our of many as empowering on centred opportunities and support provide better can we this, doing In interest. of audiences on to reflect and needs training drivers, motivational to understand areas all from staff alongside we’re working environment, cosmopolitan and busy our of nature the Given beyond. -and Institute Bioinformatics European and Institute Sanger Wellcome the –including Campus of whole to the speaks mission our Importantly, Campus. Genome Wellcome the across and within engagement of aculture support and to is enable team Engagement Public our for focus akey mind, in mission this With benefit. maximum of to be research our for communities external and us between needed relationships the and do we science pioneering the by underpinned campus research engaged world‐leading truly a to build amission with change, of journey reinvigorated we’re a on However years. many for life Campus of part a been has publics and schools with Engaging do. we what of part embedded an and bold equally is science that with engagement public our that determined are we working, multi-disciplinary and collaboration dynamic for exemplar an is Campus the on science while And data. big and biodiversity health, animal and human involving issues global challenging most the of some to tackle backgrounds of range adiverse from people together brings Campus Genome Wellcome The our training and support, and is exemplified by the STEM STEM the by exemplified is and support, and training our of much pervades practice and skills between link The 2018 March Week, Science British during attendee, course aJiffy in — Genomics material.” course the of relevance the highlighted and ease at very feel me helped It good! was very course training the after directly event evening the “Attending evaluation. and practice to reflective approach a wrap-around inspires that event public-facing areal incorporating even immersive, more are courses Some footprints. skills, story-telling, enhancing and digitalperformance building, confidence engagement, to public introductions include examples skills: of range awide covers and points entry multiple provides modules development and training of suite new Our mission. to our important very is journeys engagement and career personal their on are staff where reflects that support Providing Campus. Wellcome Genome acrossand the engagement within a culturesupport of is to enable and Engagement team Public our for A key focus the coming years. coming the over heights new exciting to reach striving audiences, and community our with together and, Campus the for aspirations our to pursuing forward looking We are Campus. Genome Wellcome the at engagement public for time ambitious amore been never has It Engagement Public Head, Skeldon, — Kenneth pursuits.” research major within efforts engagement embedding to steps first taking toall -from speak that through-roads and mechanisms support while creating Campus off and on both tocommunities responding and listening means This us. with community whole we take our vital it’s and Campus the across research and science in the engagement public toembed journey “We’re exciting an on activities. public and schools to follow-on linked inductions of series a through months six 2to 72 just in from grown has which Campus across network Ambassador

51 PUBLIC ENGAGEMENT

CONNECTING SCIENCE 54 Who we are ScientificConferences Advanced Courses and Wellcome Campus Genome research taking on the place Wellcome Campus. Genome learningsupports measures and attitudes, drawing on the ground-breaking on people. Connecting Science inspires new thinking, sparks conversation, creating opportunities spaces and to explore genomic science its and impact society. We connect researchers, health professionals the and wider public, toeveryone explore genomic science its and impact on research, health and Wellcome Campus Genome Connecting Science’s mission is to enable Olivares, Emily Sullivan, Dr Louise Walker Louise Dr Sullivan, Emily Olivares, Boldú Laura Norman, Mike Dr Gilmore, Rebecca Scott, Steve Dr Gale, Francesca Danson, Mark Skeldon Kenneth Dr Team by led Campus. Genome Wellcome the on place takes that science sharingsupports and discussion of the pioneering Engagement Public Wellcome Campus Genome Whitham Nigel Webb, Rebecca Tirelli, Sophia Suckling, John Siwek, Bart Mace, Kat Loffman, Rebecca Tanya Hudgell, Butler, Kelly Prior Linda Team by led research community. scientific the in sharing knowledge for designed spaces meeting and event world-class boasts Centre Conference Wellcome Campus Genome Yvonne Thornton, Kate Waite, Zoey Willard Zoey Waite, Kate Thornton, Yvonne Taylor, Sue Stevens, Nicola Schatlowski, Nicole Dr Ormond, Julie Offord, Sarah Matimba, Alice Dr Hughes, Darren Dr Hubbard, Laura Criddle, Lucy Creavin, Treasa Dr Crewdson, Adam Chappell, Karon Black, Pamela Dr Beard, Jemma Aslett, Martin Twells Rebecca Dr Team by led healthcare. in genomics of application the and biomedicine, cutting-edge research, basic span that fund, develop and deliver training and conferences

and Ethicsand Research Wellcome Campus Genome Society Connecting Science Director’s Office Wellcome Campus Genome Roberts Jonathan Morley, Kate Dr Farley, Lauren Middleton Anna Dr Team by led genomics. of impact ethical and social psychological, the to investigate methods research qualitative and quantitative uses Emily Boldy, Dr Ireena Dutta, Katrina Robinson Katrina Dutta, Ireena Dr Boldy, Emily Rayner Julian Dr by Team lead theacross programme. support communications and marketing provides and strategic projects, manages funding and governance, coordinates Office Director’s Science Connecting The

Mahidol University, Bangkok, Thailand Royal of Pathologists College King’s London College Kenya Nairobi, Institute, Research Medical Kenya Genetics Human of Congress International Uruguay Medicine, Tropical and Hygiene of Institute Schools in Research for Institute Diseases Tropical Neglected for Society International Atlas Cell Human Horizon 2020, European Commission England Education Health H3ABioNet H3Africa Genomic NursingGlobal Alliance Health and Genomics for Alliance Global England Genomics Board Registration Counsellor Genetic FutureLearn EB Connect Malawi of University Medicine, of College USA Laboratory, Harbor Spring Cold Popularisation Science for Institute Research China Cancer Research UK Cambridge Science Festival Centre Science Cambridge Café Scientifique Association Science British Babraham Institute Centres Discovery and Science of Association Counsellors and Nurses Genetic of Association Education Science for Association Genetics Human for Society African Our partners and networks and Our partners Institute Sanger Wellcome Wellcome Genome Campus Sweden Uppsala, of University Rica Costa of University Africa Town, South Cape of University Bank Cell Stem UK Counsellors Genetic of Alliance Transnational Studio Wayne Macgregor STEM Ambassadors Foundation Mobility Social Royal of Pathologists College Caribe yel Latina América PulseNet Institute Teaching Princes Peterborough STEM Festival Organisation Health American Pan Vietnam Unit, Research Clinical University Oxford One Nucleus OCR Genetics Nature Network Learning STEM National Engagement Public for Centre Coordinating National Museums Association Gambia The Unit MRC Biology Molecular of Laboratory MRC Association Industry Meetings Cambridge Meet Connecting Science is funded by Wellcome

55 ANNUAL REVIEW 2017/18 CONNECTING SCIENCE 56 Publications Middleton A Middleton C, Benjamin L, Badzek Tonkin E, M, Kirk KA, Calzone Genomics.and Nursing of Landscape Global The A Middleton C, Patch 2017;245:89-93. 29295058 PMID: Inform. Technol Health Stud S. Metcalfe A, Newson C, J, Hickerton Savard C, Gaff E, Turbitt R, Tytherleigh B, Wilson B, Terrill R, Stephen K, Gray Testing.Genomic Personal Direct-to-Consumer of Aspects Informatics Health Consumer 29259772 PMID: A J, Middleton Roberts for patients, consumers and citizens. Genetics in the 21st Century: Implications 17;12(1):7 Feb 2018 29454384 PMID: Genomics. Hum Health. and Genomics for Alliance Global Task Team the of Values Participant E; Kleiderman M, Murtagh LL, Rodriguez N, Bonhomme M, Corpas S, Nelson A Middleton B, J, Prainsack Bobe A, Thorogood data. genomic uninterpreted participants to individual level and patients for APPLaUD: access A Middleton Society and personal genome data. 29575600 25. PMID: Mar 2018 Genet. Med A J, Middleton Austin S, Macaulay TM, Wessels K, MY, Barlow-Stewart Laurino KE, Ormond now? we are Where globally: counseling Genetic genomicof medicine. Genetic counselling in the era 2018 Apr 2. PMID: 29608246 2. PMID: Apr 2018 29617718 2. PMID: Apr 2018 Mar 7. 29522190 Mar 2018 PMID: Genet. Mol . Hum . Br Med Bull. Bull. Med . Br . Version 2. F1000Res. 2017 Nov 17. 2017 Nov 2. F1000Res. . Version . J Nurs Scholarsh. . JNurs . Am J Med Genet C Semin CSemin Genet JMed . Am

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Oct;173(10):2649-2658. 28817238 PMID: Your DNA, Your Say.Your DNA, 28777929 PMID: 3;101(2):167-176. 2017 Aug Genet. JHum Am Review. A Middleton R, Isasi L, Hercher NA, Garrison WA, Faucett LC, Brody Y, DT, DP, Bombard Scholes Mortlock KE, Ormond Human Germline Genome Editing. TF, Hansen H, Ullum KS, MW, Burgdorf Boolsen A, Sundby incident findings genomic research. in and pertinent receiving toward attitudes their and psychiatry Stakeholders in 2017 Apr 22;389(10079):1603-1604. 28443545 2017 Apr PMID: V, A Middleton Parry Socialising the genome. 28517993PMID: A Middleton Middleton A Middleton . New Bioeth. 2017 Apr;23(1):74-80. Bioeth. . New , Musunuru K, Shriner D, Virani A, Young CE. CE. Young A, D, Virani Shriner K, , Musunuru , Mors O. Am J Med Genet A. 2017 A. Genet JMed O. Am , Mors . Lancet. . Lancet.

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Credits The District The by: Designed – – – – – – – – – – – – – – – by: Photography Prior Linda Twells, Rebecca Scott, Steve Skeldon, Kenneth Roberts, Jonathan Rayner, Julian Middleton, Anna Matimba, Alice Ireena Dutta, Rebecca Gilmore, Darren Hughes, Creavin, Treasa Boldy, Emily Boldu, Olivares Laura by: created Articles Dutta Ireena and Boldy Emily Compiled edited and by: Gavin Williams, Tin Pot Films (p11) Films Pot Tin Williams, Gavin (p21, 49) Images Wellcome (p09) Medicine of College Malawi of University (p32) Sheffield Tapton School, (p39) 904890700 iStock Sguler, top) 53 (p35, Lawniczak Mara trichuris muris Institute, Sanger Wellcome Goulding, David bottom) (p47 Wellcome Gilbert, Ben 45) (p06, Limited Research Genome (p22) Limited Research Genome Farley, Lauren 16) (p15, ADianes Jose 25, 41, 42,(p03, 47 top, 51, 52, bottom) 53 Limited Research Genome Danson, Mark (p37, 47 middle) Claxton Julian (p19) Camlin Matt (p12) Vietnam Unit Research Clinical University Baker, Oxford Stephen (p26)

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