PartnerRe Trigger Pharmaceuticals (at 2.6.20)

Code Description Drug Code Description Drug J0800 repository corticotropin injection ������������������ Acthar® J1743 idursulfase...... Elaprase® J9216 interferon gamma-1B...... Actimmune® J7205 antihemophilic factor viii...... Eloctate® J9042 brentuximab vedotin...... Adcetris® J3590 tagraxofusp-erzs...... Elzonris® J7192 factor viii recombinant nos �����������������������������Advate® J9176 elotuzumab...... Empliciti® J7207 antihemophilia factor viii, pegylated...... Adynovate® J9055 cetuximab...... Erbitux® J7210 recombinant human factor viii ����������������������� Afstyla® J7192 factor viii recombinant nos...... Esperoct® J1931 laronidase...... Aldurazyme® J1428 eteplirsen...... Exondys 51® J8999 alectinib...... Alecensa® J0180 agalsidase beta...... Fabrazyme® J7186 von Willebrand Factor...... Alphanate® J7198 anti-inhibitor coagulant complex ���������������� Feiba NF® Complex/antihemophilic. J1744 icatibant...... Firazyr® J7201 factor ix recombinant...... Alprolix® J8499 amifampridine...... Firdapse® J8999 brigatinib...... Alunbrig® J9307 pralatrexate...... Folotyn® J9302 ofatumumab...... Arzerra® J8499 migalastat...... Galafold® J1599 immune globulin...... Asceniv® J3590 emapalumab-izsg...... Gamifant®

intravenous [human]-slra J1569 IVIG Immune globulin...... Gammagard Liquid® J7196 antithrombin recombinant ������������������������������� Atryn® J1566 IVIG Immune globulin...... Gammagard® J7198 factor ix anti-inhibitor...... Autoplex T F® J1561 IVIG immune globulin...... Gammaked® coagulant complex J1557 IVIG immune globulin...... Gammaplex® J9035 bevacizumab...... Avastin® J1561 IVIG immune globulin...... Gamunex-C® C9399 Iobenguane I 131...... Azedra® J3490 givosiran...... Givlaari® J8999 erdafitinib...... Balversa® J0599 C1 esterase inhibitor subcutaneous �����������Haegarda® J9023 avelumab...... Bavencio® J7192 factor viii recombinant nos...... Helixate® J9032 belinostat...... Beleodaq® J7170 emicizumab-kxwh...... Hemlibra® J7195 factor ix recombinant...... BeneFIX® J1559 immune globulin...... Hizentra®/ J0597 C1 esterase inhibitor concentrate ����������������Berinert® subcutaneous, human...... Hizentra 20%

J9039 blinatomumab...... Blincyto® J7187 von Willebrand Factor...... Humate-P® J8999 zanubrubtinib...... Brukinsa® Complex/antihemophilic J3590 caplacizumab-yhdp...... Cablivi® J7202 factor ix recombinant...... Idelvion® J8999 cabozantinib...... Cabometyx® J8999 enasidenib...... Idhifa® J8999 cabozantinib...... Cabometyx® J0638 canakinumab...... Ilaris® J8999 acalabrutinib...... Calquence® J8999 ibrutinib...... Imbruvica® J8499 carglumic acid...... Carbaglu® J9173 durvalumab...... Imfinzi® J1566 IVIG immune globulin, nanofiltered ����� Carimune NF® J8999 fedratinib...... Inrebic® J1786 imiglucerase...... Cerezyme® J9315 romidepsin...... Istodax® J8499 chenodiol...... Chenodal® J7208 factor viii recombinant nos ����������������������������������� Jivi® J8499 cholic acid...... Cholbam® J9354 ado-trastuzumab emtansine �������������������������Kadcyla® J0598 C1 esterase inhibitor...... Cinryze® J1290 ecallantide...... Kalbitor® J7175 coagulation factor X [human] ���������������������Coagadex® J8499 ivacaftor...... Kalydeco® J7180 factor xiii antihemophilic factor ��������������������Corifact® J2840 sebelipase alfa...... Kanuma® J0584 burosumab-twza...... Crysvita® J9271 pembrolizumab...... Keytruda® J9308 ramucirumab...... Cyramza® J7190 factor viii...... Koate® J9145 daratumumab...... Darzalex® J7192 factor viii recombinant nos...... Kogenate® J8999 glasdegib...... Daurismo® J8499 mifepristone...... Korlym® J8499 metyrosine...... Demser® J7211 recombinant human factor viii ���������������������Kovaltry®

TRX020620 | 1 0f 2 PartnerRe Trigger Pharmaceuticals (at 2.6.20)

Code Description Drug Code Description Drug J2507 pegloticase...... Krystexxa® J0596 C1 esterase inhibitor recombinant ������������� Ruconest® Q2042 tisagenlecleucel...... Kymriah® J8499 amifampridine...... Ruzurgi® J9285 olaratumab...... Lartruvo® J1300 eculizumab...... Soliris® J3590 cemiplimab-rwlc...... Libtayo® J2326 nusinersen...... Spinraza® J8999 lorlatinib...... Lorbrena® J3357 ustekinumab...... Stelara® J0221 alglucosidase alfa...... Lumizyme® J8999 regorafenib...... Stivarga® J3590 moxetumomab pasudotox-tdfk ������������������� Lumoxiti® J3590 asfotase alfa...... Strensiq® J3490 lutetium lu 177 dotatate...... Lutathera® J2860 siltuximab...... Sylvant® J3398 voretigene neparvovec-rzyl...... Luxturna® J8499 tezacaftor/ivacaftor and ivacaftor ���������������Symdeko® J8999 olaparib...... Lynparza® J3590 Vyndaqel...... Tafamidis® J7599 cladribine...... Mavenclad® J8999 dabrafenib mesylate...... Tafinlar® J8999 trametinib...... Mekinist® J3590 lanadelumab-flyo...... Takhzyro® J3397 vestronidase alfa-vjbk...... Mepsevii® J8999 bexarotene...... Targretin® J7190 factor viii, human...... Monoclate-P® J8999 tazemetostat hydrobromide ������������������������� Tazverik® Q5107 bevacizumab awwb...... Mvasi® J9022 atezolizumab...... Tecentriq® J3590 metreleptin...... Myalept® J3490 inotersen...... Tegsedi® J1458 galsulfase...... Naglazyme® J8999 teprotumumab-trbw...... Tepezza® J7182 factor viiii recombinant...... NovoEight® J7197 antithrombin III, human...... Thrombate® J7189 recombinant human factor viia...... NovoSeven RT® J7181 factor xiii recombinant...... Tretten® J2796 romiplostim...... Nplate® J8499 elexacaftor/tezacaftor/ivacaftor �������������������� Trikafta® J2182 mepolizumab...... Nucala® J8999 pexidartinib...... Turalio® J7209 factor viii recombinant...... Nuwiq® J1303 ravulizumab-cwvz...... Ultomiris® J7188 antihemophilia factor, recombinant ��������������� Obizur® J9303 panitumumab...... Vectibix® J1568 IVIG immune globulin...... Octagam® J8999 abemaciclib...... Verzenio® J3590 patisiran...... Onpattro® J1322 elosulfase alfa...... Vimizim® J9299 nivolumab...... Opdivo® J8999 larotrectinib...... Vitrakvi® J8499 lumacaftor/ivacaftor...... Orkambi® J8999 dacomitinib...... Vizimpro® J3490 pegvalise-pqpz...... Palynziq® J3490 golodirsen...... Vyondys 53® J9295 necitumumab...... Portrazza® J7183 von Willebrand Factor Complex ����������������������Wilate® J9204 mogamulizumab-kpkc...... Poteligeo® J8999 gilteritinib...... Xospata® J1459 IVIG immune globulin...... Privigen® J8999 selinexor...... Xpovio® J7194 factor ix complex...... Profilnine® J8999 enzalutamide...... Xtandi® J1301 edaravone...... Radicava® J7185 recombinant human factor viii �����������������������Xyntha® J8499 glycerol phenylbutyrate...... Ravicti® J9228 ipilimumab...... Yervoy® J7203 factor ix antihemophilic factor ��������������������� Rebinyn® Q2041 axicabtagene ciloleucel...... Yescarta® J7192 factor viii recombinant nos...... Recombinate® J8999 niraparib...... Zejula® J3590 elapegademase-lvlr...... Revcovi® J8999 vemurafenib...... Zelboraf® J7178 fibrinogen concentrage [human] ������������������� Riastap® J3590 onasemnogene abeparvovec-xioi ������������Zolgensma® J7200 factor ix recombinant...... Rixubis® J8999 vorinostat...... Zolinza®

Members utilizing trigger pharmaceuticals should be reported to PartnerRe as per the terms of the reinsurance agreement. Reporting format and instructions can be found at: https://partnerre.com/risk-solutions/health/ in the documents titled PULSE Plus report.xlsx.

TRX020620 | 2 0f 2