Downloaded from Eudravigilance Website

Total Page:16

File Type:pdf, Size:1020Kb

Downloaded from Eudravigilance Website INNOPHARM3 ORGANISING COMMITTEE Chairman Dr. Avijeet Jain Co-Chairman Dr. Anurekha Jain General Secretary Dr. Alok Pal Jain Secretary Dr. Prateek Jain & Dr. Narendra Lariya Joint Secretary Dr. M L Kori Co-ordinator Dr. Gaurav K Saraogi Scientific Committee Registration Committee Dr. Rajesh Pawar (Co-ordinator) Dr. Prabhat Jain (Co-ordinator) Dr. Manish Chaurasia Dr. Sushil Kasaw Dr. Lokesh Deb Dr. Ashish Jain Dr. Kapil Khatri Dr. Yuvraj Singh Dangi Dr. Alka Pradhan Dr. Shailesh Jain Dr. Awesh Yadav Dr. Santram Lodhi Dr. Surendra Saraff Dr. Umesh Gupta Dr. Aditya Ganesh Purkar Dr. Jayesh K.M. Rajgopal Dr. Rupesh Gautam Dr. Umesh Tilrande Mrs. Noopur Trivedi Dr. M S Sudeesh Dr. Kajal Shilpi Dr. Vishnu Pal Dr. Madhu Gupta Dr. Kirti Jain Dr. Santosh Bhadoriya Mr. Shrikrishna Baokar Dr. Dinesh Mishra Dr. Reenu Yadav Ms Priti Tagde Mr. Harish Chandrawanshi Dr. Ramandeep Singh Proceeding Committee Hospitality and Transportation Committee Dr. Piush Khare (Co-ordinator) Dr. Arun Pandey (Co-ordinator) Dr. Satish Shilpi Mr. Anuj Asati Dr. R B Goswami Mr. F A Toppo Dr. Vikash Sharma Dr. Vishal Jain Mr. Mukesh Patel Dr. Abhishek Pal Dr. Manoj Goyal Mr. Ashish Singhai Dr. Deependra Singh Media Committee Finance and Sponsorship Committee Mr. Anaytullah (Co-ordinator) Dr. Arvind Gulbake (Co-ordinator) Mr. Madhur Sharma Mr. Alok Kesaharwani Mr. Neelesh Sahu Mr. Rakesh Sahu Publicity Committee Sight Seeing Committee Dr. Harsita Jain (Co-ordinator) Dr. Sunil Mistry (Co-ordinator) Mr. Anchal Kesharwani Mr. Gourav Sahu Dr. Anamika Pandey Dr. Rakesh Sagar International Board Members Dr. Wong Tin Wui Dr. V. Ravichandran Dr. Aysu Yurdasiper Dr. Payal Agrawal (Malasiya) (Malasiya) (Turkey) (USA) Dr. Wesley L. C. Ribeiro Dr. Kamlesh sahu Dr. Maitree Suttajit Dr. Alok Nahata (Brazil) (USA) (Thailand) (Malasiya) Dr. Morakot Dr. Idress Hamad Attitalla Dr. Tarang Nema Sukchotiratana Dr. Chaiyavat Chaiyasut (Libya) (Singapur) (Thailand) (Thailand) Dr. Ammar Al-Temimi Dr. Xiangming (Kain) Wu Dr. Raghavendra HL Dr. Norhaniza Aminudin (Iraq) (Corvallis) (Ethiopia) (Malasiya) Dr. Milind Arai Dr. Duc P. Do Dr. Shilpi Bhargava (Dr.) Payam Peymani (Taiwan) (Chicago) (Germany) (Iran) Dr. Umego, Ekene Dr. Mohammed Abdel-Wahab Sayed Dr. Luiz Augusto da Dr. Jegathambigai Christopher Abourehab Silva Rameshwar Naidu (Nigeria) (KSA) (Brazil) (Malaysia) Dr. Yasmin Abdel Latif Dr.yasser qasim Mahmoud Dr. Nahlah Elkudssiah Ismail almajidi Farzaneh Mohamadpour (Ezypt) (Malaysia) (Iraq) (Iran) National Board Members Dr. Sunil K Jain Dr. Vimal Jain Dr. Neera Sahai Dr. Navneet Khurana Dr. Sushma Talegaonkar Dr. Sarvesh Paliwal Dr. Neeraj Mishra Dr. Satya Prakash Singh Dr. Pushpendra Triphati Dr. Sumit bhattacharya Dr. Simant Sharma Dr. Rakesh Yadav Dr. Sanjay Jain Dr. D.K Saraf Dr. D K Sharma Dr. Gurmeet Chawada Dr. Pushpendra Jain Dr. Swapnil Sharma Dr. Deeraj Ahirwal Dr. Ajay Sharma Dr. Sanmati Jain Dr. Jaya divedi Dr. Prachi Saxena Dr. Amol Kesharwani Dr. Anshuman Shukla Dr. Sunil Dubey Dr. Pawan Jain Dr. Aditya Travedi Dr. Raviendra Chourasia Dr. Gaurav Jain Dr. Mahesh Prasad Dr. Syed Ibrahim Rizvi Dr. Davindra Soni Dr. Manju Rawat Dr. Ashok Budwani Dr. S Siddique Dr. Vijay Mishra Dr. Mukesh Sharma Dr. Manoj Goyal Prof. C J Verma Dr. R P Patel Dr. Suresh Janadri Dr. Myle Akshay Kiran Dr. Nitin Jain Dr. Neelesh M Patel Dr. Dnyaneshwar Jadhav Dr. Murari Lal Soni Dr. Garima Modi Dr. Harish Rajak Dr. Ankur Vaidhya D. Nagasamy Venkatesh Dr. Sunil Kumar Jain Dr. Nitin K Jain Dr. Shashank Singh Dr. Pushpendra Tripathi Dr. Prem Narayan Gupta Dr.S.Rajeshkumar Dr. Kavita Rohit Dr. Vikas Jain Dr. B. Gowramma Dr. Ram Lakhan Singh Dr. Praveen Kumar Sharma Mr. Dileep Singh Baghel Dr. A.Sanjeeva Kumar Dr. Dhivya Ravichandran Dr. Sudipta Das Dr. Rashmi Saxena Pal Dr. Pranav Kumar Prabhakar Dr. D. Praveen Dr. Neeta Raj Sharma Dr. Regi Raphael K Dr. Venkateswarlu Konuru Prof. (Dr.) Vipin Saini Dr. Tanveer Naved Industrial Board Members Dr. Amit Nayak Mr. Amit Jain Dr. Vaibhav Dubey Dr. Yaswant Gupta Dr. Anubhav Jain Dr. Neeraj Sethiya Dr. Manish kumar Tiwari Dr. Ashish Saxena Dr. Jaywant Thakur Dr. Vikesh Jain Dr. Manoj Nahar Dr. Davynai Dubey Dr. Gaurav Pathak Mr. Manish Rai Mr. Pankaj Jain Mr. Lalit Mishra Mr. Rajendra S. Rajput Mr. Tusar Samal Mr. Punit Jain Mr. A.K. Gupta Mr. Rakesh Ranjan Mr. Bharat Phatak Mr. Sanjay Mittal Mr. Akhil Chincholikar Mr. Gourav Bhaiji Mr. Mukul Kathriya Mr. Ashish Saxena Mr. Amol Pahariya Mr. Manish Rai Mr. Rahul Nayak Mr. Vivek Jain Mr. Khagesh Anuragi Eminent Committee Members Mr. Akshat Sharma Dr. Nilesh Jain Dr. Sudheesh Kumar Ms. Neha Jain Dr. Goapl Garg Dr. Satish shilpi Dr. Pradeep Singor Dr. Neeraj upmanyu Dr. Shailesh Sharma Dr. Rakesh Sagar Dr. Shailesh Jain Dr. Nidhi Jain Mr. Sharad Pandey Mr. Amerendra Mr. Prabhat Jain Mr. Arun Patel Mr. Rajesh Athya Mr. Abhishek Mr. Ajaj Khan Dr. Awesh Yadav Dr. Vishnu Raj Mr. Nitin Dwivedi Dr. Karunakar Shukla International Co-ordinators Dr. Azat Mukhametov Dr. Mayank Thakur Dr. Majid Asadi (Iran) Dr. Payan peymani (Iran) (Russia) (Germany) Dr. Barkat ali Khan Dr. Saneesh Kumar (South Dr. Abdeen Omer (Sudan) Dr. Ruba Kello (Syria) (Pakistan) Africa) Dr. Dadan Rohdiana Dr. Aziza Menouni Mr. Niranjan Bhattarai (Indonesia) (Morocco) Dr. Amer A Taqa (Iraq) (Nepal) Dr. Anas Tarik Alhamdany Dr. Md. Mustafizur Rahman (Iraq) INDEX S.NO ABSTRACT TITLE PAGE NO. KEYNOTE / INVITED SPEAKERS 1. POLYPHARMACOLOGY OF NATURAL PRODUCTS HARNESSED FROM TERRESTRIAL AND MARINE BIODIVERSITY IN MAURITIUS–CURRENT STATUS AND FUTURE PERSPECTIVES 2 2. NOVEL DRUG DELIVERY SYSTEMS AND INNOVATION–TRANSITIONING PHARMACEUTICAL WORLD 3 3. DRUGS FROM OUR ANCESTORS-ETHNOPHARMACOLOGY AND VALIDATION 4 4. EFFECT OF CHALANA KRIYAS, YOGASANA, KAPALABHATI, PRANYAMA, SURYA NAMASKAR, MEDITATION IN MANAGEMENT OF HYPERGLYCEMIA 5 5. INVESTIGATION OF AFRICAN MEDICINAL PLANTS–PHYTOCHEMICAL ANALYSIS, PHARMACOKINETIC HERB-DRUG INTERACTIONS INVOLVING TRADITIONAL HERBAL MEDICINES and CYTOCHROME P450 ENZYMES–IN VITRO METABOLISM, mRNA EXPRESSION AND PHYTOCHEMICAL FINGERPRINTING STUDIES 6 6. BIOLOGICAL ACTIVITIES OF MARINE SPONGES FROM PERSIAN GULF A REVIEW 7 7. SECONDARY METABOLITES PRODUCTION: PHARMACEUTICAL INDUSTRY 8 8. SYNTHESIS OF HETEROCYCLIC COMPOUNDS VIA MULTI-COMPONENT REACTIONS: THEIR MICROBIAL STUDIES AND ANTIPROLIFERATIVE ON HUMAN LUNG CANCER CELLS A549 9 9. DRUG REPURPOSING USING VIRTUAL HIGH THROUGHPUT SCREENING: FROM MODELING TO REALITY 10 10. “WONDERS AND WORRIES OF NANO MEDICINES IN HEALTH CARE” 11 ORAL PRESENTATION 11. A MIRACULOUS NANOMEDICINE: NANOROBOTICS 13 12. COMPARATIVE ANALYSIS OF THE IN VITRO ANTIOXIDANT POTENTIAL OF ETHANOLIC EXTRACTS OF HYBANTHUS ENNEASPERMUS LINN. AND BAUHINIAFOVEOLATA DALZELL-TWO INDIGENOUS PLANTS OF THE WESTERN GHATS OF INDIA 14 13. A COMPARATIVE STUDY BETWEEN EFFICACY OF CYCLOSPORINE 0.1% AND REBAMIPIDE 2% EYE DROPS IN MODERATE TO SEVERE DRY EYE CASES 15 14. ANTIHYPERLIPIDEMIC EFFECTS OF 7-METHOXY COUMARIN ON STREPTOZOTOCIN INDUCED CHANGES IN EXPERIMENTAL RATS 16 15. APPLICATION OF FACTORIAL DESIGN FOR VALIDATION OF HIGH-PERFORMANCE THIN LAYER CHROMATOGRAPHY METHOD FOR ROBUSTNESS DETERMINATION OF PHENOLIC ACIDS (GALLIC ACID, FERULIC ACID, CHLOROGENIC ACID AND CAFFEIC ACID) IN SELECTED INDIAN BAMBOO SPECIES 17 16. DROSPIRENONE INDUCED GALL BLADDER DISEASES: A RETROSPECTIVE STUDY OF EUDRAVIGILANCE DATABASE 18 17. MICROWAVE -ASSISTED SYNTHESIS AND EVALUATION OF SOME CHALCONE DERIVATIVES AS ANTI- OXIDANT AGENTS 19 18. SIMULTANEOUS ESTIMATION AND ANALYTICAL METHOD DEVELOPMENT, VALIDATION FOR THE TENELIGLIPTIN AND METFORMIN BY RP-UFLC 20 19. DESIGN AND EVALUATION OF RAMOSETRON HYDROCHLORIDE MOUTH DISSOLVING FILM 21 20. NON -INVASIVE SCORING SYSTEMS FOR HEPATIC FIBROSIS IN USG DIAGNOSED NAFLD IN TYPE2 DM 22 21. FABRICATION AND EVALUATION OF RITONAVIR CONTROLLED RELEASE TABLETS FOR EFFECTIVE ANTI- HIV THERAPY 23 22. PRECLINICAL TOXICOLOGICAL EVALUATION (ACUTE, SUB ACUTE TOXICITY) OF STANDARDIZED PLANT EXTRACTS SELAGINELLA BRYOPTERIS ON WISTAR RATS 24 23. ANTIGLYCATING BIO-ACTIVES AND PROBIOTICS SYNERGISTICALLYIMPROVES PRE-DIABETIC CONDITION 25 24. DESIGN AND DEVELOPMENT OF ROBOTIC JAW FOR THE IN VITRO DISSOLUTION TESTING OF MEDICATED CHEWING GUM 26 25. MECHANISM OF ACTION OF AYURVEDIC MEDICINE IN INHIBITION OF PRO INFLAMMATORY CYTOKINE PRODUCTION 27 26. DESIGN AND DEVELOPMENT OF TRANSGEL NANOFORMULATION FOR THE TREATMENT OF OSTEOPOROSIS 28 27. COMPARATIVE STUDY OF HERBAL EXTRACT OF PIPER NIGRUM, PIPER ALBUM AND PIPER LONGUM ON VARIOUS CHARACTERISTICS OF ISONIAZID AND RIFAMPICIN MICROSPHERES 29 28. A PROSPECTIVE OBSERVATIONAL STUDY ON DRUG UTILIZATION PATTERN IN MEDICAL INTENSIVE CARE 30 UNIT OF A TERTIARY MEDICAL CARE HOSPITAL 29. HOMOLOGY MODELING OF 14-ALPHA LANOSTEROL DEMETHYLASE 31 30. CARDIOVASCULAR COMPLICATIONS IN STREPTOZOTOCIN INDUCED DIABETIC RATS AND POTENTIAL INFLUENCE OF BETA BLOCKERS 32 31. ADVANCES IN ORAL PROLONGED DELIVERY OF METFORMIN HCL USING NANOPARTICLES AS CARRIERS TO TREAT TYPE 2 DIABETES MELLITUS 33 32. FORMULATION AND EVALUATION OF HYDRALAZINE HYDROCHLORIDE BUCCAL FILMS BY SOLVENT CASTING METHOD USING DIFFERENT POLYMERS FOR THE MANAGEMENT OF PREGNANCY INDUCED HYPERTENSION 34 33. IMPACT OF CLINICAL PHARMACIST INTERVENTION ON HYPERTENSIVE WOMEN AND PATIENT OUTCOMES AT A TERTIARY CARE HOSPITAL 35 34. INHALABLE PULMONARY STRATEGY FOR EFFECTIVE DELIVERY OF SYNERGISTIC DRUG COMBINATION IN COMBATING TUBERCULOSIS 36 35. KOKILAKSHAM KASHAYAM, AN AYURVEDIC HERBAL PREPARATION IS AN INHIBITOR OF PRO- INFLAMMATORY CYTOKINES AND NO IN THP 1 DERIVED MACROPHAGES 37 36. STEM CELLS AS A NOVEL TOOL FOR WOUND
Recommended publications
  • Activity of Povidone in Recent Biomedical Applications with Emphasis on Micro- and Nano Drug Delivery Systems
    pharmaceutics Review Activity of Povidone in Recent Biomedical Applications with Emphasis on Micro- and Nano Drug Delivery Systems Ewelina Waleka 1,2 , Zbigniew Stojek 1 and Marcin Karbarz 1,* 1 Faculty of Chemistry, Biological and Chemical Research Center, University of Warsaw, 101 Zwirki˙ i Wigury Av., PL 02-089 Warsaw, Poland; [email protected] (E.W.); [email protected] (Z.S.) 2 Faculty of Chemistry, Warsaw University of Technology, 1 Pl. Politechniki Av., PL 00-661 Warsaw, Poland * Correspondence: [email protected] Abstract: Due to the unwanted toxic properties of some drugs, new efficient methods of protection of the organisms against that toxicity are required. New materials are synthesized to effectively disseminate the active substance without affecting the healthy cells. Thus far, a number of poly- mers have been applied to build novel drug delivery systems. One of interesting polymers for this purpose is povidone, pVP. Contrary to other polymeric materials, the synthesis of povidone nanoparticles can take place under various condition, due to good solubility of this polymer in several organic and inorganic solvents. Moreover, povidone is known as nontoxic, non-carcinogenic, and temperature-insensitive substance. Its flexible design and the presence of various functional groups allow connection with the hydrophobic and hydrophilic drugs. It is worth noting, that pVP is regarded as an ecofriendly substance. Despite wide application of pVP in medicine, it was not often selected for the production of drug carriers. This review article is focused on recent reports on the role povidone can play in micro- and nano drug delivery systems.
    [Show full text]
  • (12) United States Patent (10) Patent No.: US 8,940,728 B2
    USOO894.0728B2 (12) UnitedO States Patent (10) Patent No.: US 8,940,728 B2 Mash et al. (45) Date of Patent: Jan. 27, 2015 (54) SUBSTITUTED NORIBOGAINE 5,152.994. A 10/1992 Lotsof 5,283,247 A 2f1994 Dwivedi et al. (71) Applicant: DemeRx, Inc., Miami, FL (US) 5,316,7595,290,784. A 3/19945/1994 Quetal.Rose et al. 5,382,657 A 1/1995 K. tal. (72) Inventors: Deborah C. Mash, Miami, FL (US); 5,426,112 A 6, 1995 ity a Richard D. Gless, Jr., Oakland, CA 5,552,406 A 9, 1996 Mendelson et al. (US); Robert M. Moriarty, Michiana 5,574,052 A 1 1/1996 Rose et al. Shores, IN (US) 5,578,645 A 11/1996 Askanazi et al. s 5,580,876 A 12/1996 Crain et al. 5,591,738 A 1, 1997 LotSof (73) Assignee: DemeRx, Inc., Miami, FL (US) 5,618,555 A 4/1997 Tokuda et al. - 5,703,101 A 12/1997 Rose et al. (*) Notice: Subject to any disclaimer, the term of this 5,726, 190 A 3, 1998 Rose et al. patent is extended or adjusted under 35 S.S.; A s 3. th. 1 U.S.C. 154(b)(b) bybV 144 davs.ayS 5,865.444.wwk A 2/1999 KempfetOSe et al. al. 5,925,634 A 7/1999 Olney (21) Appl. No.: 13/732,751 5,935,975 A 8/1999 Rose et al. 6,211,360 B1 4/2001 Glicket al. (22) Filed: Jan. 2, 2013 6,291.675 B1 9/2001 Coop et al.
    [Show full text]
  • The Alkaloids: Chemistry and Biology
    CONTRIBUTORS Numbers in parentheses indicate the pages on which the authors’ contributions begin. B. EMMANUEL AKINSHOLA (135), Department of Pharmacology, College of Medicine, Howard University, Washington, DC 20059, eakinshola@ howard.edu NORMA E. ALEXANDER (293), NDA International, 46 Oxford Place, Staten Island, NY 10301, [email protected] SYED F. ALI (79, 135), Division of Neurotoxicology, National Center for Toxicological Research, 3900 NCTR Road, Jefferson, AR 72079, [email protected] KENNETH R. ALPER (1, 249), Departments of Psychiatry and Neurology, New York University School of Medicine, 550 First Avenue, New York, NY 10016, [email protected] MICHAEL H. BAUMANN (79), Clinical Psychopharmacology Section, Intra- mural Research Program, NIDA, National Institutes of Health, Baltimore, MD 21224, [email protected] DANA BEAL (249), Cures-not-Wars, 9 Bleecker Street, New York, NY 10012, [email protected] ZBIGNIEW K. BINIENDA (193), Division of Neurotoxicology, National Cen- ter for Toxicological Research, 3900 NCTR Road, Jefferson, AR 72079, [email protected] WAYNE D. BOWEN (173), Laboratory of Medicinal Chemistry, NIDDK, NIH, Building 8 B1-23, 8 Center Drive, MSC 0820, Bethesda, MD 20892, [email protected] FRANK R. ERVIN (155), Department of Psychiatry and Human Genetics, McGill University, Montreal, Quebec H3A 2T5, Canada, md18@musica. mcgill.ca JAMES W. FERNANDEZ (235), Department of Anthropology, University of Chicago, 1126 E. 59th Street, Chicago, IL 60637, jwfi@midway. uchicago.edu xi xii CONTRIBUTORS RENATE L. FERNANDEZ (235), Department of Anthropology, University of Chicago, 1126 E. 59th Street, Chicago, IL 60637, rlf2@midway. uchicago.edu GEERTE FRENKEN (283), INTASH, P.O.
    [Show full text]
  • Brochure Dubbed 140909
    Andhi Toofan Director : Chi Gurudutt Music : Vidyasagar Aaj Ka Krantiveer Year of release : 2008 Cast : Sudeep, Vaibhavi, Pooja Gandhi Director : Uday Shankar Synopsis : Kamanna (Doddanna) has brought up Ramanna (Sudeep) and Kittanna (Rockline Venkatesh) Music : Vidyasagar from childhood. All the three are efficient thieves. One fine day they all decide to give up their Year of release : 2001 profession of stealing and settle down in some other place. They are traveling in a lorry that develops mechanical defect in the midst of a forest on a dark night. Luckily, they find a house in the next Cast : Vijaykanth, Soundarya morning to live. This is the house of Kanaka (Vaibhavi). Her father is facing a difficult situation in front Synopsis : Vijaykant plays the role of a respected village elder Thavasi, whose word is law. He also of the village chieftain. The stay of trio in this house gives some relief and courage to the distressed plays the younger character too, that of Bhoopathy, Thavasi's son where he gets to romance - sing family. The trio - Kamanna and his two sons barge in to the chieftain's house to resolve the litigation further angers the village chieftain. and dance, and fight too. Soundarya, is cast as his fiance, whereas Jayasudha plays Thavasi's wife The trio decides to stay in this village thereafter doing cultivation. In a village fair, Ramanna ties the mangalasutra to Gayathri, daughter of and Nasser plays Pandy, Thavasi's brother-in-law and the villain of the piece. village chieftain. The village chieftain give up his harshness for the sake of his daughter Gayathri.
    [Show full text]
  • Near the Himalayas, from Kashmir to Sikkim, at Altitudes the Catholic Inquisition, and the Traditional Use of These of up to 2700 Meters
    Year of edition: 2018 Authors of the text: Marc Aixalà & José Carlos Bouso Edition: Alex Verdaguer | Genís Oña | Kiko Castellanos Illustrations: Alba Teixidor EU Project: New Approaches in Harm Reduction Policies and Practices (NAHRPP) Special thanks to collaborators Alejandro Ponce (in Peyote report) and Eduardo Carchedi (in Kambó report). TECHNICAL REPORT ON PSYCHOACTIVE ETHNOBOTANICALS Volumes I - II - III ICEERS International Center for Ethnobotanical Education Research and Service INDEX SALVIA DIVINORUM 7 AMANITA MUSCARIA 13 DATURA STRAMONIUM 19 KRATOM 23 PEYOTE 29 BUFO ALVARIUS 37 PSILOCYBIN MUSHROOMS 43 IPOMOEA VIOLACEA 51 AYAHUASCA 57 IBOGA 67 KAMBÓ 73 SAN PEDRO 79 6 SALVIA DIVINORUM SALVIA DIVINORUM The effects of the Hierba Pastora have been used by Mazatec Indians since ancient times to treat diseases and for divinatory purposes. The psychoactive compound Salvia divinorum contains, Salvinorin A, is the most potent naturally occurring psychoactive substance known. BASIC INFO Ska Pastora has been used in divination and healing Salvia divinorum is a perennial plant native to the Maza- rituals, similar to psilocybin mushrooms. Maria Sabina tec areas of the Sierra Madre Oriental Mountains of Mexi- told Wasson and Hofmann (the discoverers of its Mazatec co. Its habitat is tropical forests, where it grows between usage) that Salvia divinorum was used in times when the- 300 and 800 meters above sea level. It belongs to the re was a shortage of mushrooms. Some sources that have Lamiaceae family, and is mainly reproduced by cuttings done later feldwork point out that the use of S. divinorum since it rarely produces seeds. may be more widespread than originally believed, even in times when mushrooms were abundant.
    [Show full text]
  • The Iboga Alkaloids
    The Iboga Alkaloids Catherine Lavaud and Georges Massiot Contents 1 Introduction ................................................................................. 90 2 Biosynthesis ................................................................................. 92 3 Structural Elucidation and Reactivity ...................................................... 93 4 New Molecules .............................................................................. 97 4.1 Monomers ............................................................................. 99 4.1.1 Ibogamine and Coronaridine Derivatives .................................... 99 4.1.2 3-Alkyl- or 3-Oxo-ibogamine/-coronaridine Derivatives . 102 4.1.3 5- and/or 6-Oxo-ibogamine/-coronaridine Derivatives ...................... 104 4.1.4 Rearranged Ibogamine/Coronaridine Alkaloids .. ........................... 105 4.1.5 Catharanthine and Pseudoeburnamonine Derivatives .. .. .. ... .. ... .. .. ... .. 106 4.1.6 Miscellaneous Representatives and Another Enigma . ..................... 107 4.2 Dimers ................................................................................. 108 4.2.1 Bisindoles with an Ibogamine Moiety ....................................... 110 4.2.2 Bisindoles with a Voacangine (10-Methoxy-coronaridine) Moiety ........ 111 4.2.3 Bisindoles with an Isovoacangine (11-Methoxy-coronaridine) Moiety . 111 4.2.4 Bisindoles with an Iboga-Indolenine or Rearranged Moiety ................ 116 4.2.5 Bisindoles with a Chippiine Moiety ... .....................................
    [Show full text]
  • Slno NEET ROLL CANDNM 1 2705011010 AZMAT NAZNEEN 2
    / 143 KARNATAKA EXAMINATIONS AUTHORITY 1 Sampige Road,18th Cross,Malleshwaram, Bangalore - 560012 PROVISIONAL LIST OF CANDIDATES REGISTERED FOR UGNEET-2020 - (Karnataka UGCET-2020 candidates, subsequently applied for modification for UGNEET-2020) Note 1.If any candidates has registered for UGNEET-2020 and if not listed in the following list should report to KEA with registration details. 2.Mere registration for UGNEET-2020 does not confirm any right for admission to medical or dental seats , it is subject to fulfilling eligibility conditions. 3. If any discrepancy found should report to KEA immediately. 4. Candidates should not presume that it is a merit list for UGNEET-2020 admissions. slno NEET ROLL CANDNM 1 2705011010 AZMAT NAZNEEN 2 2707003558 RHEA VANESSA RODRIGUES 3 2703007039 UMAR MUKTHAR 4 2705007525 AYESHA SIDDIQUA 5 2702218356 SAARAH I JATHKAR 6 2702316237 SHWETA JAYAKUMAR 7 2701002121 DEVIKA RAJESH KAMBLE 8 2702313195 GIRISH O 9 2707001384 ASHWIN K 10 2703006177 GANESHA S S 11 2705020033 VANISHREE KUNDAN 12 2703026031 ANILKUMAR D B 13 2701004130 KAVYA RAMESH SHET 14 2708217059 S SUBHIKSHA 15 2707004234 ZAIBA MUZNA 16 2705008148 OMER AHMED ANSARI 17 2708208264 KIRAN KODHAI P 18 2702303187 SANDHYA B 19 2706029055 NIDA AMDIHAL 20 2705001447 SANDEEP K PATIL 21 2702102179 SOBANA FAREEHA 22 2703031116 NEHA FIRDOSE 23 2703008378 CHANDANA N C 24 2707004273 RUDALI R PATIL 25 2707005430 KRITHI ALVA 26 2703017218 AAISHA FARIYAL M 27 2702121129 PRADEEP K N 28 2702122019 NETHRA K 29 2708203045 SHWETHA P 30 2702304259 HEMANNYA V 31 2707001573
    [Show full text]
  • A Short Review on Stomach Specific Drug Delivery System
    International Journal of PharmTech Research CODEN (USA): IJPRIF ISSN : 0974-4304 Vol.4, No.4, pp 1527-1545, Oct-Dec 2012 A Short Review on Stomach Specific Drug Delivery System Garima Gupta1*, Amit Singh1 1Department of Pharmaceutics, R.V. Northland Institute, Greater Noida, G. B. Nagar, U.P.,India. *Corres.author: [email protected] Abstract: Technological attempts have been made in the research and development of rate-controlled oral drug delivery systems to overcome physiological adversities, such as short gastric residence times (GRT) and unpredictable gastric emptying times (GET). Conventional oral dosage forms pose low bioavailability problems due to their rapid gastric transition from stomach, especially in case of drugs which are less soluble at alkaline pH of intestine. Similarly, drugs which produce their local action in stomach get rapidly emptied and do not get enough residence time in stomach. So, frequency of dose administration in such cases is increased. To avoid this problem, various efforts have been made to prolong the retention time of drug delivery system. In this review, we will discuss about the various approaches to produce gastro retention of drug delivery system, with current & recent developments of Stomach Specific floating drug delivery system. Key words: Gastro retention, Floating drug delivery system, Stomach specific drug delivery, gastric emptying time. INTRODUCTION:- The oral route is considered as the most promising route of drug delivery. Conventional drug delivery The oral delivery of drugs is the most preferred system achieves as well as maintained the drug route of administration due to ease of concentration within the therapeutically effective administration. Drug bioavailability of range needed for treatment, only when taken pharmaceutical oral dosage forms is influenced by several times a day.3 Drug that have narrow various factors.
    [Show full text]
  • Formulation and Evaluation of Antiseptic Polyherbal Ointment
    Research Article [Rajasree et al., 3(10): Oct., 2012] CODEN (USA): IJPLCP ISSN: 0976-7126 INTERNATIONAL JOURNAL OF PHARMACY & LIFE SCIENCES Formulation and evaluation of antiseptic polyherbal ointment P.H.Rajasree 2 ,⃰ Vidya Vishwanad 1, Merin Cherian 1, Jincy Eldhose 1 and Ranjith Singh 2 1, Department of Pharmaceutics, Amrita School of Pharmacy, Amrita Institute of Medical Science and Technology, Cochin (Kerala) - India 2, Department of Pharmaceutics, KMCH College of Pharmacy, Coimbatore, (TN) - India Abstract Herbal therapy and herbal drugs predominates in traditional medicine as well as in alternative medicine practiced in the developed world. Among the various indications where traditional herbal medicines are used, skin and skin related disorders is ranked top. Thus, the main objective of the present study is to formulate and evaluate a poly herbal ointment with antiseptic activity. Ointments were formulated using methanolic extracts (by continuous hot percolation-soxhletation) of Azadirachta indica , Chromolaena odorata ,Mimosa pudica ,Samadera indica and were evaluated for its physicochemical property, antibacterial and antioxidant activity. Ointments were prepared using different concentrations of the extracts such as 2%, 4%, 6% w/w by fusion method using emulsifying ointment as base. Formulations were then tested for its physicochemical properties like loss of drying, pH, spreadability, extrudability and diffusion study and gave satisfactory results. The prepared formulations were also stable at 4ºC, 25ºC and 37ºC. Further, polyherbal formulations were evaluated for its anti-bacterial activity against Staphylococcus aureus, Pseudomonas sp., Bacillus sp., by agar diffusion method by using Betadine (5%w/w) as the standard. All the formulations showed predominant activity against selected species.
    [Show full text]
  • Towards Soft Robotic Devices for Site-Specific Drug Delivery
    University of Wollongong Research Online Faculty of Engineering and Information Faculty of Engineering and Information Sciences - Papers: Part A Sciences 1-1-2015 Towards soft robotic devices for site-specific drug delivery Gursel Alici University of Wollongong, [email protected] Follow this and additional works at: https://ro.uow.edu.au/eispapers Part of the Engineering Commons, and the Science and Technology Studies Commons Recommended Citation Alici, Gursel, "Towards soft robotic devices for site-specific drug delivery" (2015). Faculty of Engineering and Information Sciences - Papers: Part A. 4807. https://ro.uow.edu.au/eispapers/4807 Research Online is the open access institutional repository for the University of Wollongong. For further information contact the UOW Library: [email protected] Towards soft robotic devices for site-specific drug delivery Abstract Considerable research efforts have recently been dedicated to the establishment of various drug delivery systems (DDS) that are mechanical/physical, chemical and biological/molecular DDS. In this paper, we report on the recent advances in site-specific drug delivery (site-specific, controlled, targeted or smart drug delivery are terms used interchangeably in the literature, to mean to transport a drug or a therapeutic agent to a desired location within the body and release it as desired with negligibly small toxicity and side effect compared to classical drug administration means such as peroral, parenteral, transmucosal, topical and inhalation) based on mechanical/physical systems consisting of implantable and robotic drug delivery systems. While we specifically focus on the oboticr or autonomous DDS, which can be reprogrammable and provide multiple doses of a drug at a required time and rate, we briefly cover the implanted DDS, which are well-developed relative to the robotic DDS, to highlight the design and performance requirements, and investigate issues associated with the robotic DDS.
    [Show full text]
  • A Quarter Century of Pharmacognostic Research on Panamanian Flora: a Review*
    Reviews 1189 A Quarter Century of Pharmacognostic Research on Panamanian Flora: A Review* Authors Catherina Caballero-George 1, Mahabir P. Gupta2 Affiliations 1 Institute of Scientific Research and High Technology Services (INDICASAT‑AIP), Panama, Republic of Panama 2 Center for Pharmacognostic Research on Panamanian Flora (CIFLORPAN), College of Pharmacy, University of Panama, Panama, Republic of Panama Key words Abstract with novel structures and/or interesting bioactive l" bioassays ! compounds. During the last quarter century, a to- l" Panamanian plants Panama is a unique terrestrial bridge of extreme tal of approximately 390 compounds from 86 l" ethnomedicine biological importance. It is one of the “hot spots” plants have been isolated, of which 160 are new l" novel compounds and occupies the fourth place among the 25 most to the literature. Most of the work reported here plant-rich countries in the world, with 13.4% en- has been the result of many international collabo- demic species. Panamanian plants have been rative efforts with scientists worldwide. From the screened for a wide range of biological activities: results presented, it is immediately obvious that as cytotoxic, brine shrimp-toxic, antiplasmodial, the Panamanian flora is still an untapped source antimicrobial, antiviral, antioxidant, immunosup- of new bioactive compounds. pressive, and antihypertensive agents. This re- view concentrates on ethnopharmacological uses Supporting information available at of medicinal plants employed by three Amerin- http://www.thieme-connect.de/ejournals/toc/ dian groups of Panama and on selected plants plantamedica Introduction are a major component of the Panamanian tropi- ! cal forest. Mosses abound in moist cloud forests as Medicinal plants remain an endless source of new well as other parts of the country.
    [Show full text]
  • A Perspective on Magnetic Core–Shell Carriers for Responsive and Targeted Drug Delivery Systems
    Journal name: International Journal of Nanomedicine Article Designation: Review Year: 2019 Volume: 14 International Journal of Nanomedicine Dovepress Running head verso: Albinali et al Running head recto: Albinali et al open access to scientific and medical research DOI: 193981 Open Access Full Text Article REVIEW A perspective on magnetic core–shell carriers for responsive and targeted drug delivery systems This article was published in the following Dove Medical Press journal: International Journal of Nanomedicine Kholoud E Albinali1 Abstract: Magnetic core–shell nanocarriers have been attracting growing interest owing to Moustafa M Zagho1 their physicochemical and structural properties. The main principles of magnetic nanoparticles Yonghui Deng2 (MNPs) are localized treatment and stability under the effect of external magnetic fields. Ahmed A Elzatahry1 Furthermore, these MNPs can be coated or functionalized to gain a responsive property to a specific trigger, such as pH, heat, or even enzymes. Current investigations have been focused 1Materials Science and Technology Program, College of Arts and Sciences, on the employment of this concept in cancer therapies. The evaluation of magnetic core–shell Qatar University, Doha, Qatar; materials includes their magnetization properties, toxicity, and efficacy in drug uptake and 2 Department of Chemistry, State Key release. This review discusses some categories of magnetic core–shell drug carriers based Laboratory of Molecular Engineering of Polymers, Shanghai Key Laboratory on Fe2O3 and Fe3O4 as the core, and different shells such as poly(lactic-co-glycolic acid), of Molecular Catalysis and Innovative poly(vinylpyrrolidone), chitosan, silica, calcium silicate, metal, and lipids. In addition, the Materials, iChEM, Fudan University, review addresses their recent potential applications for cancer treatment.
    [Show full text]