Data Sheet 85098-0003 -- Clock System Accessories
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TS4002 Wireless Synchronized Analog Clock Is Designed with an Easy-To-Read Dial Face, Durable Cherry Finished Wood Frame and Tamper-Proof Glass Lens
TS4002 - Wireless Synchronized Analog Clock The TS4002 Wireless Synchronized Analog Clock is designed with an easy-to-read dial face, durable cherry finished wood frame and tamper-proof glass lens. The TS4002 receives a wireless time signal transmitted daily by a main wireless paging controller, such as the VS4800. The TS4002 uses the time signal to automatically adjust itself, if necessary, to ensure accurate and synchronized time throughout the entire facility. The TS4002 does not require any wiring and is ideal for renovation projects and new installations. The TS4002 has a traditional look that matches a wide variety of applications and provides years of maintenance-free service. Key Features: • Viewing Distance of 50' • Automatic Daylight Saving Time Adjustment • Glass Lens • Quick Correction for Time Change (1-3 Minutes) • Flush Mount (Does Not Require Back Box) • Battery Operated (Optional AC Power Adaptor) • Customized Logo Option Options, Accessories and Complementary Products: Part Number Description TS-OPT-003 24-Hour Clock Face TS-OPT-004 Customized Analog Clock Face TS-OPT-005 Sealed Analog Clock TS-OPT-007 110 V AC Adaptor (Replaces Original Clock Batteries, Requires 1.5" Minimum Recessed Power Outlet) TS-OPT-011 Red Second Hand Specifications: Dimensions 19.5" x 8.5" x 2.05" (W x H x D) Dial Face 8", White Weight 5.25 lbs. Frequency VHF (148 - 174 MHz), UHF (400 - 470 MHz) Power Two AA Sized Batteries Paging Format POCSAG, Narrow Band Operating Temperature 32º - 120ºF Synchronization 1 Time/Day (Optional 6 Times/Day, User Selectable) Humidity 0% - 95%, Non-Condensing Receiver Sensitivity 10u V/M Frame and Lens Wood Durable Frame, Glass Lens Limited Warranty One Year Parts and Labor Viewing Distance 50 ft. -
75324T-Instructions.Pdf
Atomic Digital Clock with indoor/outdoor temperature, calendar and moon phase MODEL # 75324T USER GUIDE Package Contents: (1) Atomic Digital Clock (1) Wireless Outdoor Temperature Sensor (1) User Guide NOTE: A clear protective flm is applied to the LCD at the What You’ll Need: factory that must be removed prior to using this product. (8) AA Batteries Locate the clear tab and simply peel to remove. Thank you for purchasing this quality TIMEX® brand product. Please read these instructions COMPLETELY to fully understand the features and functions of this clock, and to enjoy its benefts. Make sure to keep this guide handy for future reference. To receive product information, register your product online. It's quick & easy! Log on to http://www.chaneyinstrument.com/ProductReg.aspx WHAT IS AN ATOMIC CLOCK? An Atomic clock is a timepiece that maintains accuracy up to one second per million years using the most precise method of time synchronization, radio signals. In North America, the National Institute of Standards and Technologies (NIST) operates an Atomic clock in Fort Collins, Colorado, that transmits the time codes via the radio station WWVB. Please DO NOT return product to the retail store. For technical assistance This quality TIMEX® clock includes a built-in receiver that picks up the Atomic radio signal from WWVB. To and product return information, please call technical support @ 877-221-1252 maintain the best possible reception, place the unit so that the backside faces in the general direction of Monday - Friday -- 8:00 a.m. - 4:30 p.m. CST Colorado. What's more, the IntelliTime® technology built into this clock makes for hassle-free automatic setting and resetting for daylight saving time. -
Flexible. Affordable. Built to Last. 2 It’S a Good Bet There’S Not a Single Person in America, Who’S Listened to The
D-75 STANDALONE AND D-75N NETWORKABLE DIGITAL AUDIO CONSOLES Flexible. Affordable. Built To Last. 2 It’s a good bet there’s not a single person in America, who’s listened to the radio in the last 10 years, who hasn’t heard an Audioarts radio console in action. That’s how pervasive and powerful this product line is. 3 Wheatstone D-75 STANDALONE DIGITAL AUDIO CONSOLE When it comes to radio consoles, Wheatstone’s Audioarts is Individual plug-in the de facto standard. And our D-75 is the state of the art. modules make It’s got everything you need to produce, air and manage all of installation and your programs. It’s powerful and flexible enough to please any service a breeze. engineer, simple enough that even guest talent feel at home and Configuration is as cost-effective enough to make management smile. simple as setting the front panel dipswitches Available in two frame sizes, 12 input (13 max) and 18 input concealed under the (21 max), the D-75 comes standard with 4 mic preamps and hinged meterbridge. gives you plenty of stereo busses, dual phone caller capability Digital and analog input channel daughtercards make field and a comprehensive monitor section that provides separate conversions simple and fast. Easy access logic programming feeds to control room/headphone and studio monitor outputs. dipswitches make configuration changes a snap. Plus, the D-75 gives you an output module, external power supply, two LED meter pairs, digital clock and timer, headphone Best of all, the D-75 is designed by the Wheatstone engineering jack, and built-in cue speaker (dual phone module and line team so you know its construction quality and performance selector module shown are optional). -
Please Replace the Following Pages in the Book. 26 Microcontroller Theory and Applications with the PIC18F
Please replace the following pages in the book. 26 Microcontroller Theory and Applications with the PIC18F Before Push After Push Stack Stack 16-bit Register 0120 143E 20C2 16-bit Register 0120 SP 20CA SP 20C8 143E 20C2 0703 20C4 0703 20C4 F601 20C6 F601 20C6 0706 20C8 0706 20C8 0120 20CA 20CA 20CC 20CC 20CE 20CE Bottom of Stack FIGURE 2.12 PUSH operation when accessing a stack from the bottom Before POP After POP Stack 16-bit Register A286 16-bit Register 0360 Stack 143E 20C2 SP 20C8 SP 20CA 143E 20C2 0705 20C4 0705 20C4 F208 20C6 F208 20C6 0107 20C8 0107 20C8 A286 20CA A286 20CA 20CC 20CC Bottom of Stack FIGURE 2.13 POP operation when accessing a stack from the bottom Note that the stack is a LIFO (last in, first out) memory. As mentioned earlier, a stack is typically used during subroutine CALLs. The CPU automatically PUSHes the return address onto a stack after executing a subroutine CALL instruction in the main program. After executing a RETURN from a subroutine instruction (placed by the programmer as the last instruction of the subroutine), the CPU automatically POPs the return address from the stack (previously PUSHed) and then returns control to the main program. Note that the PIC18F accesses the stack from the top. This means that the stack pointer in the PIC18F holds the address of the bottom of the stack. Hence, in the PIC18F, the stack pointer is incremented after a PUSH, and decremented after a POP. 2.3.2 Control Unit The main purpose of the control unit is to read and decode instructions from the program memory. -
Play Clock Operator Guide
NFHS GENERAL INSTRUCTIONS FOR FOOTBALL GAME AND PLAY CLOCK OPERATORS A. The game and play clock operators should report to the game officials at the stadium at least 30 minutes before game time for the following purposes: 1. To synchronize timer’s watch with official game time as established by the game official responsible for timing. 2. To advise game officials whether the game clock operator and/or play clock operator will be in the press box or on the field/side- line. Determine procedure for communications with both operators and test procedures prior to the games. 3. To discuss coordination of starting, stopping and adjusting the game clock or play clock in accordance with the playing rules. 4. To discuss if the game clock horn (mechanical signal) can be turned off. Preference is for the game clock horn (mechanical signal) to be turned off for the duration of the game. B. The game clock is normally started 30 minutes before game time. The halftime intermission will start on the referee’s signal when the players and game officials leave the field. All pregame and halftime activities shall be synchronized with the game clock. The mandatory three-minute warm-up period will be put on the game clock after the intermission time has elapsed and shall be started immediately. C. The game clock operator shall have an extra stopwatch available. In case of failure of the game clock, the game clock operator shall immediately contact the game officials, giving them the correct data regarding the official time. The game official responsible for timing will then pick up the correct game time on the stopwatch. -
Agonists and Knockdown of Estrogen Receptor Β Differentially Affect
Schüler-Toprak et al. BMC Cancer (2016) 16:951 DOI 10.1186/s12885-016-2973-y RESEARCH ARTICLE Open Access Agonists and knockdown of estrogen receptor β differentially affect invasion of triple-negative breast cancer cells in vitro Susanne Schüler-Toprak1*, Julia Häring1, Elisabeth C. Inwald1, Christoph Moehle2, Olaf Ortmann1 and Oliver Treeck1 Abstract Background: Estrogen receptor β (ERβ) is expressed in the majority of invasive breast cancer cases, irrespective of their subtype, including triple-negative breast cancer (TNBC). Thus, ERβ might be a potential target for therapy of this challenging cancer type. In this in vitro study, we examined the role of ERβ in invasion of two triple-negative breast cancer cell lines. Methods: MDA-MB-231 and HS578T breast cancer cells were treated with the specific ERβ agonists ERB-041, WAY200070, Liquiritigenin and 3β-Adiol. Knockdown of ERβ expression was performed by means of siRNA transfection. Effects on cellular invasion were assessed in vitro by means of a modified Boyden chamber assay. Transcriptome analyses were performed using Affymetrix Human Gene 1.0 ST microarrays. Pathway and gene network analyses were performed by means of Genomatix and Ingenuity Pathway Analysis software. Results: Invasiveness of MBA-MB-231 and HS578T breast cancer cells decreased after treatment with ERβ agonists ERB-041 and WAY200070. Agonists Liquiritigenin and 3β-Adiol only reduced invasion of MDA-MB-231 cells. Knockdown of ERβ expression increased invasiveness of MDA-MB-231 cells about 3-fold. Transcriptome and pathway analyses revealed that ERβ knockdown led to activation of TGFβ signalling and induced expression of a network of genes with functions in extracellular matrix, tumor cell invasion and vitamin D3 metabolism. -
Design and Implementation of a Broadband RF-DAC Transmitter for Wireless Communications
Design and Implementation of a Broadband RF-DAC Transmitter for Wireless Communications Von der Fakultät für Elektrotechnik und Informationstechnik der Rheinisch-Westfälischen Technischen Hochschule Aachen zur Erlangung des akademischen Grades eines Doktors der Ingenieurwissenschaften genehmigte Dissertation vorgelegt von Diplom-Ingenieur Niklas Zimmermann aus Münster Berichter: Universitätsprofessor Dr.-Ing. Stefan Heinen Universitätsprofessor Dr.-Ing. Gerd Ascheid Tag der mündlichen Prüfung: 1. Juli 2011 Diese Dissertation ist auf den Internetseiten der Hochschulbibliothek online verfügbar. Bibliografische Information der Deutschen Nationalbibliothek Die Deutsche Nationalbibliothek verzeichnet diese Publikation in der Deutschen Nationalbibliografie; detaillierte bibliografische Daten sind im Internet über http://dnb.d-nb.de abrufbar. ISBN 978-3-8439-0042-3 D 82 (Diss. RWTH Aachen University, 2011) © Verlag Dr. Hut, München 2011 Sternstr. 18, 80538 München Tel.: 089/66060798 www.dr.hut-verlag.de Die Informationen in diesem Buch wurden mit großer Sorgfalt erarbeitet. Dennoch können Fehler nicht vollständig ausgeschlossen werden. Verlag, Autoren und ggf. Übersetzer übernehmen keine juristische Verantwortung oder irgendeine Haftung für eventuell verbliebene fehlerhafte Angaben und deren Folgen. Alle Rechte, auch die des auszugsweisen Nachdrucks, der Vervielfältigung und Verbreitung in besonderen Verfahren wie fotomechanischer Nachdruck, Fotokopie, Mikrokopie, elektronische Datenaufzeichnung einschließlich Speicherung und Übertragung auf weitere Datenträger sowie Übersetzung in andere Sprachen, behält sich der Autor vor. 1. Auflage 2011 To the memory of my father, Gebhard Zimmermann Acknowledgment First of all, I want to thank Prof. Dr.-Ing. Stefan Heinen. This thesis would not have been possible without him, as he gave me the opportunity to work on this exciting topic and shared his rich experience in the field of RF and analog circuit and system design with me. -
Neurobiological Functions of the Period Circadian Clock 2 Gene, Per2
Review Biomol Ther 26(4), 358-367 (2018) Neurobiological Functions of the Period Circadian Clock 2 Gene, Per2 Mikyung Kim, June Bryan de la Peña, Jae Hoon Cheong and Hee Jin Kim* Department of Pharmacy, Uimyung Research Institute for Neuroscience, Sahmyook University, Seoul 01795, Republic of Korea Abstract Most organisms have adapted to a circadian rhythm that follows a roughly 24-hour cycle, which is modulated by both internal (clock-related genes) and external (environment) factors. In such organisms, the central nervous system (CNS) is influenced by the circadian rhythm of individual cells. Furthermore, the period circadian clock 2 (Per2) gene is an important component of the circadian clock, which modulates the circadian rhythm. Per2 is mainly expressed in the suprachiasmatic nucleus (SCN) of the hypothalamus as well as other brain areas, including the midbrain and forebrain. This indicates that Per2 may affect various neurobiological activities such as sleeping, depression, and addiction. In this review, we focus on the neurobiological functions of Per2, which could help to better understand its roles in the CNS. Key Words: Circadian rhythm, Per2 gene, Sleep, Depression, Addiction, Neurotransmitter INTRODUCTION and lives in organisms because it can impart effects from the level of cells to organs including the brain. Thus, it is neces- A circadian rhythm is any physiological process that displays sary to understand clock-related genes that are controlling the a roughly 24 hour cycle in living beings, such as mammals, circadian rhythm endogenously. plants, fungi and cyanobacteria (Albrecht, 2012). In organ- The Period2 (Per2) gene is a member of the Period family isms, most biological functions such as sleeping and feeding of genes consisting of Per1, Per2, and Per3, and is mainly patterns are adapted to the circadian rhythm. -
The Period of the Circadian Oscillator Is Primarily Determined by the Balance Between Casein Kinase 1 and Protein Phosphatase 1
The period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1 Hyeong-min Leea,1,2, Rongmin Chena,1, Hyukmin Kima, Jean-Pierre Etchegarayb,3, David R. Weaverb, and Choogon Leea,4 aDepartment of Biomedical Sciences, College of Medicine, Florida State University, Tallahassee, FL 32306; and bDepartment of Neurobiology, University of Massachusetts Medical School, Worcester, MA 01605-2324 Edited by Joseph S. Takahashi, Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX, and approved August 30, 2011 (received for review May 4, 2011) Mounting evidence suggests that PERIOD (PER) proteins play a PAGE—occurs progressively over several hours (12, 19), which is central role in setting the speed (period) and phase of the circadian critical for stretching the feedback loop to ∼24 h. However, PER2 clock. Pharmacological and genetic studies have shown that changes can be maximally phosphorylated by CK1ε in vitro kinase reac- in PER phosphorylation kinetics are associated with changes in tions within 30 min (20, 21), suggesting that PER phosphorylation circadian rhythm period and phase, which can lead to sleep disorders must be counterbalanced by phosphatases in vivo. such as Familial Advanced Sleep Phase Syndrome in humans. We Because the phase and period of the clock are primarily de- and others have shown that casein kinase 1δ and ε (CK1δ/ε) are termined by temporal regulation of PER phosphorylation (12, 15, essential PER kinases, but it is clear that additional, unknown mech- 21–26), the characterization of PER kinases and phosphatases is anisms are also crucial for regulating the kinetics of PER phosphor- vital to understanding the circadian clock mechanism. -
Electronic LED Digital Clock Model:CX-808 User Manual
Electronic LED Digital Clock Model:CX-808 User Manual Operation: (1) Butting (2) Setting Of Time and Date: 1- Under normal situation, press SET to begin the setting of date and time, and you will see the hour and minute displays showing the year with flash at the same time; 2- Press MODIFY to change year (if you don’t want to change the flashing number, do not press modify, the following steps are in the same way); press flash on month display, and then change the month by press MODIFY; press SHIFT to move the flash on day display, and then change the day by pressing MODIFY. During the process of setting, the week follows the date changing automatically; 3- Press SHIFT again, the date disappears and the hour flashes, then change the hour by pressing MODIFY; press SHIFT to more the flash or minute display, and then change the minute by pressing MODIFY. 4- Press SET again to resume the normal situation. (3) 12 and 24 hour mode, under normal situation, press MODIFY for 3 second to switch between 12 and 24-hour mode. (4) Hour Notice Setting: Under normal situation press MODIFY to open or close the hour notice function, and you will see the indicator on or off. (5) Setting Of Alarm: 1- Under normal situation, press ALARM to view the set alarm time, the alarm indicator light is bright. When you see “A1” on the temperature display position, it means what you see on time display is the first group of alarm time. If the time display shows”-:--“it means this group of alarm is workable when it shows time, press MODIFY to switch between workable and unworkable. -
A Mutant Drosophila Homolog of Mammalian Clock Disrupts
Cell, Vol. 93, 791±804, May 29, 1998, Copyright 1998 by Cell Press AMutantDrosophila Homolog of Mammalian Clock Disrupts Circadian Rhythms and Transcription of period and timeless Ravi Allada,*²³§ Neal E. White,³ Aronson et al., 1994; Shearman et al., 1997; Sun et al., W. Venus So,²³ Jeffrey C. Hall,²³ 1997; Tei et al., 1997). ²³ and Michael Rosbash* k In Drosophila, there are two well-characterized clock *Howard Hughes Medical Institute genes: period (per) and timeless (tim). Protein levels, ² NSF, Center for Biological Timing RNA levels, and transcription rates of these two genes ³ Department of Biology undergo robust circadian oscillations (Zerr et al., 1990; Brandeis University Hardin et al., 1990, 1992; Hardin, 1994; Sehgal et al., Waltham, Massachusetts 02254 1995; So and Rosbash, 1997). In addition, mutations § Department of Pathology in the two proteins (PER and TIM) alter or abolish the Brigham and Women's Hospital periodicity and phase of these rhythms, demonstrating Boston, Massachusetts 02115 that both proteins regulate their own transcription (Har- din et al., 1990; Sehgal et al., 1995; Marrus et al., 1996). Although there is no evidence indicating that the effects Summary on transcription are direct, PER contains a PAS domain, which has been shown to mediate interactions between We report the identification, characterization, and transcription factors (Huang et al., 1993; Lindebro et cloning of a novel Drosophila circadian rhythm gene, al., 1995). Most of these PAS-containing transcription dClock. The mutant, initially called Jrk, manifests dom- factors also contain the well-characterized basic helix- inant effects: heterozygous flies have a period alter- loop-helix (bHLH) DNA-binding domains (Crews, 1998). -
Circadian Rhythmicity and the Influence of 'Clock
2311 Z Kiss and P M Ghosh Prostate cancer and the 23:11 T123–T134 Thematic Review ‘clock’ genes WOMEN IN CANCER THEMATIC REVIEW Circadian rhythmicity and the influence of ‘clock’ genes on prostate cancer Zsofia Kiss1,2 and Paramita M Ghosh1,2,3 1VA Northern California Health Care System, Mather, California, USA Correspondence 2Department of Urology, University of California at Davis, Sacramento, California, USA should be addressed 3Department of Biochemistry and Molecular Medicine, University of California at Davis, Sacramento, to P M Ghosh California, USA Email [email protected] Abstract Key Words The androgen receptor (AR) plays a key role in the development and progression f circadian clock of prostate cancer (CaP). Since the mid-1990s, reports in the literature pointed out f androgen receptor higher incidences of CaP in some select groups, such as airline pilots and night shift f melatonin workers in comparison with those working regular hours. The common finding in these f per1 ‘high-risk’ groups was that they all experienced a deregulation of the body’s internal f bmal1 circadian rhythm. Here, we discuss how the circadian rhythm affects androgen levels and modulates CaP development and progression. Circadian rhythmicity of androgen Endocrine-Related Cancer Endocrine-Related production is lost in CaP patients, with the clock genes Per1 and Per2 decreasing, and Bmal1 increasing, in these individuals. Periodic expression of the clock genes was restored upon administration of the neurohormone melatonin, thereby suppressing CaP progression. Activation of the melatonin receptors and the AR antagonized each other, and therefore the tumour-suppressive effects of melatonin and the clock genes were most clearly observed in the absence of androgens, that is, in conjunction with androgen deprivation therapy (ADT).