List of Senior Scientists Université De Bordeaux Campus D’Excellence

IdEx Bordeaux University of Bordeaux Campus of Excellence

IdEx Bordeaux List of senior scientists Université de Bordeaux Campus d’excellence

(acting as points of contact)

Post-doctoral fellowship

programme 2013

2013 IdEx Bordeaux post-doctoral fellowship programme List of senior scientists

Archeology ...... 2 Biotechnology ...... 3 Cancer ...... 3 Cardiology ...... 3 Environment and Ecosystem ...... 3 Health policy ...... 5 Lasers and Photonics ...... 5 Materials science ...... 8 Neurosciences ...... 9 Numerical certification and reliability ...... 10 Public health ...... 11 Regenerative medicine ...... 11 Translational Imaging ...... 12

Archeology

Bruno Maureille (Director of researcher CNRS, UMR 5199 PACEA, CNRS-UB1) Email: [email protected] Within the frame of LaScArBx Cluster of excellence’s first research topic, “Settlements and Territories”, Bruno Maureille’s team works on human settlements from a global perspective, considering physical environments, human and biological diversity, animal settlement, material cultures and social and political structures of complex societies.

Pierre Guibert (Research Engineer CNRS, UMR 5060 IRAMAT-CRP2A, CNRS-UB3) Email: [email protected] Within the frame of LaScArBx Cluster of excellence’s second research topic, “Exploitation, Innovation, Echange”, Pierre Guibert’s team studies the exploitation conditions of natural resources by prehistoric and historical societies from three perspectives: technical, economic and cultural. It addresses issues such as production specialisation, technical innovations and power relations.

Valérie Fromentin (Professor of Greek Language and Literature, UMR 5607 AUSONIUS, CNRS-UB3) Email: [email protected] Within the frame of LaScArBx Cluster of excellence’s third research topic, “Expressions of the Symbolic and Spaces of Memory”, Valérie Fromentin’s team works on various spaces (material and immaterial) which were endowed by Man with a memory function, whether these “memory spaces” were designed and created as such by past populations or considered and promoted as such by modern ones.

2013 IdEx Bordeaux post-doctoral fellowship programme 2/13

Biotechnology

Bertrand Garbay Email : [email protected] New protein polymers for synthetic biology

Cancer

Jean Rosenbaum Email : [email protected]

Pierre Soubeyran Email : [email protected]

Cardiology

Pierre Jaïs (MD) Email : [email protected] Cardiology, clinical cardiac electrophysiology, cardiac arrhythmia ablation, electroanatomical mapping

Hubert Cochet (MD) Email : [email protected] Radiology, multimodal cardiac imaging

Olivier Bernus, PhD, scientific director of IHU in cardiology Email : [email protected] Experimental cardiac electrophysiology, optical imaging, MRI, computer modeling

Environment and Ecosystem

Antoine Kremer (INRA – Population and quantitative genetics) Email : [email protected] INRA – Population and quantitative genetics Antoine Kremer is senior scientist at INRA Bordeaux (France). He received his phD in quantitative genetics and habilitation degree in population genetics at the University of Paris (Orsay). His research deals with the evolution of genetic diversity and differentiation between natural tree populations, at various hierarchical levels where diversity is expressed (from genes to phenotypic traits). Antoine Kremer initiated Europe-wide forestry research as early as the 1980s based on population genetics and evolutionary biology. His research has focused on the evolution of oaks across Europe, investigated by complementary approaches including paleobotany, population genetics and computer simulations. His current interest addresses future evolution in the context of environmental changes, using microevolutionary approaches by linking genetics, genomics and ecology.

2013 IdEx Bordeaux post-doctoral fellowship programme 3/13

Hélène Budzinski (CNRS - Physico- and Toxico-Chemistry of the environment) Email : [email protected] Hélène Budzinski (46 years old) is a CNRS research director and in charge of the LPTC (Laboratory of Physico- and Toxico-Chemistry of the environment) which is a research group of EPOC (UMR 5805 University Bordeaux 1/CNRS). She is co-director of COTE LabEx. In 1989 she graduated as an engineer of the ENSCP of Paris, defended her PhD thesis in 1993 at the Bordeaux University, and got her HDR in 1999. Her research focuses on various classes of organic contaminants (PAHs, PCBs, pesticides, pharmaceutical substances, endocrine disruptors, detergents,…) studying presence, fate and toxic impacts. She has coordinated various projects in the case of national calls for proposal among them the LITEAU project (2003) on pharmaceutical substances and the ANR EMESTOX project dealing with passive samplers. She has been or is also involved, as principal investigator, in 10 ANR projects (e.g., ANR AMPERES) as well as in 7 European projects. She is the author of more than 200 publications (h-index: 39), of 56 invited international conferences and she was awarded several prizes: the brass medal of the CNRS (1995), the French Chemistry Society (SFC) prize for the analytical chemistry division (1997), the ADEME prize for environment innovative techniques (1998, 2002, 2010); she is Knight of the National Order of the Merit (2009). She has been since 2008 a member of several scientific councils such as those of ONEMA, IRD, Chronic Risk Division of the INERIS, Planet and Universe CNRS Institute. She was the co-coordinator of the GDR IMOPHYS; she is also co-coordinating the GDR EXECO. She has supervised 24 PhD students, eight post-docs and ATERs. H. Budzinski takes part, as a teacher, in various research and professional Master degrees (University Bordeaux 1, ENSCPB, AgroParisTech).

Denis Salles (IRSTEA - Environmental sociology and public policy) Email : [email protected] Denis Salles is Director of Research at IRSTEA (National Research Institute of Science and Technology for Environment and Agriculture) in unity "Amenities and Dynamics of Rural Areas" in Bordeaux Centre. He is in charge of the Chair of Excellence Aquitaine since 2009. He conducts research in environmental sociology and public policy that focuses on how societies adapt to the impacts of global change (www.adapteau.fr), modes of water governance, measures to increase users accountability, participatory sciences devices.

Prof. E. Villenave (University of Bordeaux – CNRS, France – Atmospheric Chemistry) Email : [email protected] Prof. E. Villenave is 44 years old. Since 2005, he has a full-time position of Professor of Atmospheric Chemistry at the University of Bordeaux (France). Since January 2012, he is the new Director of the “Observatoire Aquitain des Sciences de l’Univers (OASU)”, an observatory of both CNRS and the University of Bordeaux, counting in his perimeter around 500 researchers, engineers, technicians, PhD students and post-docs, working on different fields like air pollution, water pollution, environmental chemistry, ecotoxicology, paleoclimatology, oceanography, astrophysics, astronomy, etc. For the last 15 years, he has been involved mainly in mechanistic studies of radical reactions of tropospheric interest. More recently, he has developed new activities related to field measurements. He spent one year in 1996-1997 working at the National Institute of Standards and Technology (MD, USA). His group collaborates with several groups in France and Europe, and in the United States, and has many PhD students and post-docs. He was involved in the French National Program on Atmospheric Chemistry, the French National Programme PRIMEQUAL on the Air Quality, has participated to 5 EU-project and has conducted many research projects during the last years. He was also a member of the Scientific Committee of the French National Program on Atmospheric Chemistry; he has organized 4 national and international conferences and is the author or co-author of more than 50 peer reviewed publications and 110 communications. He has also headed during ten years the Master of Environmental Chemistry at the University of Bordeaux. Since 2009, he is chairing the French Group of Chemical Kinetics and Photochemistry and was acting the last 4 years for the Direction of CNRS as a project manager,

2013 IdEx Bordeaux post-doctoral fellowship programme 4/13 following all the different activities and programs of atmospheric interest.

Denis Loustau (INRA, Functional Ecology and Environmental Physics) Email: [email protected] D. Loustau was director of the EPHYSE (Functional Ecology and Environmental Physics) unit from 2006 to 2013 that includes 45 staff (http://www7.bordeaux-aquitaine.inra.fr/ephyse/l_unite). EPHYSE is coordinating the experimental platform XyloSylve/Ecosylve (part of the EQUIPEX XyloForest). EPHYSE is member of the LabEx (Laboratory of Excellence) “COTE” (“Continental to coastal ecosystems”) and member of its directorate. EPHYSE team is associated with Bordeaux University and CNRS-INSU through its memberships to the OASU and the Directorate of the Doctoral School 306. EPHYSE coordinates also the Ecosystem French branch of the national TGIR ICOS. D. Loustau research project investigates the vegetation-atmosphere interactions with number of applications regarding the Forest – Climate and carbon cycle interplay, radiative transfer and energy balance in complex canopies, water transfer in the soil-tree-atmosphere continuum, tree growth and wood production. This project contributes to the sustainable management of forest ecosystems and its adaptation to environmental changes. D. Loustau has been managing network of flux tower sites and long term manipulative experiments on maritime pine forests since 1987 within the SOERE F-ORE-T. He also developed a number of modeling tools and approaches in collaboration with, among others, Alterra-Wageningen, Edinburgh and MacQuarie universities. In recent years, he has been involved in several projects funded by the EU (EFORWOOD, Carbo-Extreme, GHG-Europe, EXPEER, ICOS - PP), ANR (CATS, MIST, CLIMATOR, ORACLE) and GICC (Carbofor, FAST).

Health policy

Andy Smith Email : [email protected]

Lasers and Photonics

Vincent Rodriguez - (Institute for Molecular Sciences) Email : [email protected] The expertise of the Institute of Molecular Sciences (ISM) is focused on competences dealing mainly with physical chemistry (theoretical chemistry, spectroscopies, photochemistry and analytical chemistry) and organic chemistry (synthesis of bioactive molecules, nano and supramolecular materials). Our research activities are supported by three facilities based respectively on molecular modeling, vibrationnal spectroscopic techniques and NMR and Mass spectrometries. http://www.ism.u-bordeaux1.fr/spip.php?rubrique2

Mireille Blanchard-Desce – (Institute for Molecular Sciences) Email : [email protected] The expertise of the Institute of Molecular Sciences (ISM) is focused on competences dealing mainly with physical chemistry (theoretical chemistry, spectroscopies, photochemistry and analytical chemistry) and organic chemistry (synthesis of bioactive molecules, nano and supramolecular materials). Our research activities are supported by three facilities based respectively on molecular modeling, vibrationnal spectroscopic techniques and NMR and Mass spectrometries. http://www.ism.u-bordeaux1.fr/spip.php?rubrique2

2013 IdEx Bordeaux post-doctoral fellowship programme 5/13

Thierry Cardinal – (Institute of Condensed Matter Chemistry of Bordeaux) Email : [email protected] The Institute of Condensed Matter Chemistry of Bordeaux (ICMCB)is one of the largest French laboratories in Material Sciences. The ICMCB focuses on three research areas : Solid State Chemistry, Materials Science and Molecular Science. The main purpose consisting in designing new materails and improving their properties from a better knowledge of the chemical bonds and the structures. http://www.icmcb-bordeaux.cnrs.fr/groupes/lp-groupe3.html

Laurent Cognet – (Institut d'Optique Graduate School) Email : [email protected] The research at the LP2N of the Institute d’Optique Graduate School – Bordeaux covers fundamental and applied physics as well as interdisciplinary aspects (photonics, nanosciences, material science, biophotonics and augmented reality). More specifically, five research areas are being developped : Photons and nanosystems, Optics for biology, Artificial matter and quantum Materials, Instrumentation, hybrid systems and augmented reality and Matter waves, atom lasers and microsystems. http://www.lp2n.institutoptique.fr/

Philippe Lalanne – (Institut d'Optique Graduate School) Email : [email protected] The research at the LP2N of the Institute d’Optique Graduate School – Bordeaux covers fundamental and applied physics as well as interdisciplinary aspects (photonics, nanosciences, material science, biophotonics and augmented reality). More specifically, five research areas are being developped : Photons and nanosystems, Optics for biology, Artificial matter and quantum Materials, Instrumentation, hybrid systems and augmented reality and Matter waves, atom lasers and microsystems. http://www.lp2n.institutoptique.fr/

Brahim Lounis – (Institut d'Optique Graduate School) Email : [email protected] The research at the LP2N of the Institute d’Optique Graduate School – Bordeaux covers fundamental and applied physics as well as interdisciplinary aspects (photonics, nanosciences, material science, biophotonics and augmented reality). More specifically, five research areas are being developped : Photons and nanosystems, Optics for biology, Artificial matter and quantum Materials, Instrumentation, hybrid systems and augmented reality and Matter waves, atom lasers and microsystems. http://www.lp2n.institutoptique.fr/

Eric Constant– CELIA Email : [email protected] CELIA, Centre Laser Intenses et Applications, is a research center created to develop a local academic expertise in intense lasers in conjunction with the Laser MegaJoule program. The main competences include : laser physics, ultrashort pulse science, short wavelengths sources, atomic, molecular and condensed matter physics in extreme conditions, hot plasma physics, numerical modeling and applied mathematics, inertial fusion science. The laboratory is organized as a versatile « multi-physics » center and laser infrastructure. http://www.celia.u-bordeaux1.fr/spip.php?rubrique2

Dominique Descamps - CELIA Email : [email protected] CELIA, Center Laser Intenses et Applications is a research center created to develop a local academic expertise in intense lasers in conjunction with the Laser MegaJoule program. The main competences include : laser physics, ultrashort pulse science, short wavelengths sources, atomic, molecular and condensed matter physics in extreme conditions, hot plasma physics, numerical modeling and applied

2013 IdEx Bordeaux post-doctoral fellowship programme 6/13 mathematics, inertial fusion science. The laboratory is organized as a versatile « multi-physics » center and laser infrastructure. http://www.celia.u-bordeaux1.fr/spip.php?rubrique2

Fabien Dorchies - CELIA Email : [email protected] CELIA, Center Laser Intenses et Applications is a research center created to develop a local academic expertise in intense lasers in conjunction with the Laser MegaJoule program. The main competences include : laser physics, ultrashort pulse science, short wavelengths sources, atomic, molecular and condensed matter physics in extreme conditions, hot plasma physics, numerical modeling and applied mathematics, inertial fusion science. The laboratory is organized as a versatile « multi-physics » center and laser infrastructure. http://www.celia.u-bordeaux1.fr/spip.php?rubrique2

Vladimir Tikhonchuk – CELIA Email : [email protected] CELIA, Center Laser Intenses et Applications is a research center created to develop a local academic expertise in intense lasers in conjunction with the Laser MegaJoule program. The main competences include : laser physics, ultrashort pulse science, short wavelengths sources, atomic, molecular and condensed matter physics in extreme conditions, hot plasma physics, numerical modeling and applied mathematics, inertial fusion science. The laboratory is organized as a versatile « multi-physics » center and laser infrastructure. http://www.celia.u-bordeaux1.fr/spip.php?rubrique2

Stefan Dilhaire - LOMA Email : [email protected] The LOMA is a pillar of the Bordeaux’s fundamental Physics for several decades. Research is centered on Photonics and Condensed Matter Physics. Coupling condensed matter physics with optics, laser physics and photonics the LOMA’s research is dedicated to laser material spectroscopy, nonlinear optics, fiber laser, innovative imaging, laser nanostructuring, photomanipulation, picosecond acoustics and nanothermy, optofluidic synthesis and assembling of functional nanoobjects. http://www.loma.cnrs.fr/spip.php?rubrique10

Fazia Hannachi – CENBG Email : [email protected] CENBG (Centre d’Etudes Nucléaires de Bordeaux Gradignan) is a nuclear physics laboratory. It is organised in 7 research groupes with various activities in basic and applied nuclear science. The main competences of CENBG staff include nuclear physics, particle physics and astrophysics, theory and simulations, detector development, electronic and mechanic studies. To allow large access to nuclear physics based techniques CENBG has developed 2 multidisciplinary facilities AIFIRA (based on an ion accelerator) and PRISMA (for the measurement of very low radioactivities). http://www.cenbg.in2p3.fr/-Research-?lang=en

Denis Penninckx – CEA-CESTA Email : [email protected] Scientific and technical laser expertise of CEA-CESTA engineers encompasses three domains which constitute the core business of the Department « Lasers de Puissance » (Scientific and technological overview, technical monitoring of the industrial contracts and support to operating procedures of the LMJ and PETAL Laser facilities). The expertise of CEA-CESTA concerns the domains of laser technologies and laser metrology. http://www-dam.cea.fr/organisation-competences/cesta.html

2013 IdEx Bordeaux post-doctoral fellowship programme 7/13

Materials science

Prof Annie COLIN (Laboratory of the Future) Email : [email protected] Soft matter deals with the state of the matter that are easily deformable by thermal fluctuations. It encompasses liquids, colloids, polymers, foams, granular materials. Soft matter is used to shape the matter at the nanometric scale. Our aim is to design and imagine the future industrial process that will give raise to advanced materials for energy, optics and medical applications. Using state of the art approaches (microfluidics, numerical simulations, high through put approaches, flow of complex fluids), we will focus on printing and drying processes at high speed.

Prof Gérard VIGNOLES (composites Thermostructural Laboratory) Email : [email protected] The main purpose of Virtual Materials is to develop materials design toolboxes able to capture the main features of the structure/properties relationship, and in particular the non-ideal structural features of the “real” materials. This requires the development of characterization techniques coupled to modeling tools at different levels, and to some image analysis/synthesis routines. The target materials are related to electronic organics, electromagnetic/optical or acoustic metamaterials, biosensors- bioactuators-biofuel cell, … Approaches integrating multi-scale simulation supported by structural/textural characterization data and image analysis/synthesis are encouraged.

Dr Cyril AYMONIER (Institute of Chemistry of Condensed Matter – Bordeaux University) Email : [email protected] The main issue of sustainable chemistry and engineering is to propose and develop greener methodologies/processes for the design of advanced materials (organic, inorganic, hybrid) with applications in the fields of energy, ICT, … This is based on i) the use of renewable resources and/or the integration of the criticality concept of materials, ii) the use of green solvents as water or supercritical fluids, iii) new catalysis concepts and iv) the use of microfluidics processes. A particular attention is attached on the recyclability of the developed advanced materials.

Dr Philippe BAROIS (Paul Pascal Research Center) Email : [email protected] Metamaterials are artificial composite materials that exhibit extraordinary physical properties unknown in nature. Low or negative index of refraction at terahertz and optical frequency, optical magnetism, tunable acoustic refraction are examples of properties targeted in Bordeaux within the framework of Amadeus through a multidisciplinary approach gathering of local competences in nanochemistry, colloidal physics, optical studies, theoretical modeling and numerical simulations.

Prof Alexander KUHN (Institute for Molecular Sciences) Email : [email protected] One of our major axes aims at designing a miniaturized implantable device that is able to sense and treat a medical signal of interest in the body, to deliver a relevant drug, and to be autonomously energy-powered. With respect to this very general goal, major challenges are the design of the sensor device, combined with stimuli responsive drug delivery systems and an endogenic energy generation based on biofuel cells. A transdisciplinary aspect in this context is also the biocompatibility of these different parts as well as of their combination.

Prof Georges HADZIIOANNOU (Laboratory of Organic Polymer Chemistry) Email : [email protected] Organic electronics will allow to switch from silicon-based to organic semiconductors, which are much

2013 IdEx Bordeaux post-doctoral fellowship programme 8/13 more flexible and can be formulated in the form of inks. Our goals are (i) upgrading the chemistry of polymers and O/I hybrid compounds, (ii) understanding and controlling of electro-optical properties in relation to molecular structure, interfaces and device architecture, (iii) mechanical and thermal energy harvesting and (iv) organic MEMS.

Neurosciences

Daniel Choquet, (DRCE CNRS) Head of the team dynamics of synapse organization and function Email: [email protected] The IINS unites researchers with diverse areas of expertise, and creates a highly synergistic environment to promote the development of innovative methods and investigation tools, especially those based on molecular biology, physiology, optics, chemistry, physics and computer science. The application of such tools pushes the boundaries of the study of molecular events underlying the activity of the brain. This will include studying the morpho-dynamic and functional properties of the nervous system to understand the complexity of its molecular assemblies and functions at an integrated level.

Pier Vincenzo Piazza, NCM U862 (researcher - Pathophysiology of addiction) Email: [email protected] Directeur de recherche – PhD – Inserm The Neurocentre Magendie is an Inserm research centre, who focus on the understanding of the pathophysiology of brain diseases, in other words we study the mechanism leading to the appearance of behavioral and neurological pathologies. The Neurocentre Magendie analyzes the pathophysiology of the brain integrating all its levels of activity: i. the molecular level, to study the modifications inside the neuronal cells; ii. the network level, to understand the modalities of communication between the cells of the central nervous system; and iii. the behavior level to analyze several pathological conditions, including motor disorders, neuropathies, autism, anxiety, depression, addiction and obesity.

Erwan Bezard, IMN (researcher - Pathophysiology of parkinson's syndrome) Email: [email protected] The Institute of Neurodegenerative Diseases (IMN) aims to encompass fundamental, preclinical and clinical research in the field of neurodegenerative diseases, with the goal of developing therapeutic approaches to neurodegenerative diseases using both vertical and translational approaches. The unique combination of clinically-relevant experimental models, ranging from in vitro simplified preparations to behaving non-human primates, and of a highly dynamic clinical research allows us to actually achieve the bench-to-bedside chain of research development and valuation.

Pierre Philip, SanPsy (researcher - Neuropsychopharamacology studies in sleep, sleepiness and attention) Email: [email protected] SANPSY is a joint CNRS service and research unit working at redefining the frontier between normality and pathology in the fields of sleep, attention, addiction, attention-deficit hyperactivity disorder and new psychiatric disorders. Our major focus is on interindividual vulnerabilities to sleep loss, attention deficits and addictions. We use epidemiological studies to identify associations between these symptoms and/or disorders and cognitive/behavioural handicaps. Experiments conducted in a sophisticate research platform, combining EEG, virtual reality and cognitive psychology, aims at confirming causalities suspected in the epidemiological studies. Finally we design novative counter- measures to sleepiness, fatigue, attention deficits and addictions.

2013 IdEx Bordeaux post-doctoral fellowship programme 9/13

Jean-René Cazalets, (INCIA, Director of researcher CNRS) Email: [email protected] The INCIA federates 11 teams working in the fields of cognitive and integrative neuroscience with a focus on three main themes, Motricity, Motivation, and Cognition. Studies range from animal models to human clinical research using innovative methods in molecular biology, electrophysiology, imaging, animal behavior, psychophysics, and clinical investigations.

Sophie Layé, NutriNeuro, (Director of researcher INRA) Email: [email protected] The NutriNeuro unit researchers study the impact of lipid nutrition on brain functions and the development of mood and cognitive disorders using state of the art multidisplinary approaches from molecular biology to behavior. Our general hypothesis is that lipidic nutritional imbalances contribute to the development of cognitive and mood disorders, due to their effects on the pathophysiological processes involved in these disorders. The ambitious and innovative character of our project relies on our capacity to conduct translational research both in rodent models and humans in the emerging field of Nutrition and Neurosciences.

Numerical certification and reliability

Eric Arquis, Director – (Institute of Mechanics and Engineering of Bordeaux) Email : [email protected] In the frame of the CPU ClustEx, (EA - I2M) could be the referent (« mentor ») for the High Performance Computational Sciences from a "mechanical" point-of-view, it means in relation both to Solid Mechanics (including Physical Acoustics) and Fluid Mechanics (including Heat and Mass Transfer). It refers to the physical modeling and its numerical expression, the building of adapted algorithms, the development of solving strategies and its implementation in particular on parallel supercomputers, and the validation through experiments. The application field covers from Materials Characterization and Processing to (Coastal) Environment, through (Thermal) Energy. http://i2m.u-bordeaux.fr/departements.html

Claude Pellet, Director – (Institute for Molecular Sciences) Email : [email protected] IMS laboratory studies concern the integration of hardware, intelligence and knowledge in communicating and human centered systems. The scientific themes are as various as materials processing or materials assembly for the development of components, design and integration of components for the realization of complex electronic systems with high reliability level, systems control and systems monitoring, signal or image processing, production engineering and interaction of the systems with biological entities or with users. In the frame of the CPU ClustEx, IMS is the referent for any project related to the development of innovating methods (including algorithmic) warranting the reliability of emerging complex systems. http://www.ims-bordeaux.fr/equipe.php?guidPage=NGFkNWUxNzgxNDI1YQ==

Pascal Weil, Director - LaBRI Email : [email protected] LaBRI is a research unit covering most areas of computer science, from theory to applications: combinatorics, algorithms, formal methods, verification of complex systems, distributed systems, computer graphics, computer vision, high performance computation, networks, software engineering, bio-informatics, big data, visualization, etc. We are involved in interactions with many other scientific

2013 IdEx Bordeaux post-doctoral fellowship programme 10 /13 fields (mathematics, physic, biology and genomics, medicine, linguistics, archaeology, physical anthropology, etc). And we collaborate with a large number of companies, in the industrial and the service sectors (aeronautics, telecommunications, health services, computer or web services, robotics, etc.) both large groups and SMEs. http://www.labri.fr/index.php?n=Main.Equipes

Isabelle Terrasse, Director - INRIA Bordeaux Sud Ouest Email : [email protected] INRIA Bordeaux Sud Ouest is a research center organized around an original research model built on a basic structural element, known as the project-team. The centre’s main priorities, which benefit from world-class expertise available in the region as well as substantial external contributions, are the following : • Modelling and high-performance computation (9 project-teams) • Perception, cognition, interaction (4 project-teams) • Algorithms and programs for distributed and secure systems and networks (4 project-teams) This research activity is at the very center of the LabEx activity. http://www.inria.fr/centre/bordeaux/recherche

Jean François Jaulent, Director – (Institute of Mathematics of Bordeaux) Email : [email protected] IMB is a research unit very original in the national landscape of Mathematics since among the 8 teams, 7 have developed very high level research activities in numerical algorithms in various fields : “Number Theory” (algorithmic and computational methods, coding, cryptography…), “Analysis” (innovative mathematical methods for signal and image processing…), “Probability and Statistics” (stochastic algorithms, applications to signal filtering, rare events analysis, stochastic optimization…), “Scientific Computing and Modelling” (high performance scientific computing for compressible flows and wave propagation, numerical methods for particle system simulation, simulation of complex fluids (microfluidics, biology), simulation of tumor growth…) “Operational Research” (tight formulations such as Lagrangian and polyhedral approach, develops efficient algorithms to produce new generic softwares…), “Bio-Mathematics” (mathematical modelling of disease propagation, numerical simulation codes for disease propagation…). http://www.math.u-bordeaux1.fr/imb/rubrique7.html

Public health

François Dabis Email : [email protected]

Regenerative medicine

Joëlle Amédée Email : [email protected]

2013 IdEx Bordeaux post-doctoral fellowship programme 11 /13

Translational Imaging

Bruno Quesson Email : [email protected] MR Guided High Intensity Focused Ultra Sounds To further develop MRI guided High Intensity Focused Ultrasound towards treatment of tumors in particular for liver and kidney, as well as breast and prostate from large animals to clinical trials. Objectives: 1) The development of MRI guided HIFU for thermo-ablation of cancer in liver and kidney, as well as breast, and prostate from large animals to clinical trials; 2) The development of MRI guided HIFU for image guided drug delivery to achieve a) local release of drugs from circulating nanocarriers, b) extravasation of drugs, c) crossing natural barriers such as cell membranes, blood-brain-barrier.

Jean-Michel Franconi Email : [email protected] New MRI Contrasts – New MRI Sequences To increase spatial and temporal resolutions, increase sensitivity, increase specificity to become more quantitative and to adapt NMR/MRI to systems biology. Objectives: The effort will be focused on the development on 3D, real-time and whole body sequences for morphological, functional and molecular and cellular MRI. Three main and interconnected steps: sequences design and implantation, preclinical evaluation on small animals and transfer to clinical research and applications. Dynamic Nuclear Polarization A risk-taking breakthrough research of new Targeted DNP-Contrast Enhanced MRI for diagnosis through protease spotting. Objective: to use dynamic nuclear polarization and specific free-radical-based contrast agent to target disease-associated protease activities.

Eric Fouquet Email : [email protected] Radiopharmaceutical Tracers and Contrasts Agents To create responsive agents for molecular imaging, using different imaging modalities towards functional imaging (MR, PET and Optical)

Klaus G. Petry Email: [email protected] Targeted Biological Markers for Bio-Imaging The imaging biomarkers serve in prediction of patients at risk, in diagnosis of patients, in evaluation of disease progression, in disease prognosis and in evaluation of therapeutic interventions. Objective: Two major strategies: 1) The tropism of cellular infiltration (macrophages, T cells, mesenchymal stem cells); 2) The molecular alterations of endothelial cells recognized by specific ligands

Thierry COLIN Email : [email protected] Mathematical Simulation and Modelling To compute patient-specific digital models from multimodal imaging data in order to reproduce diseases and treatments in silico. Objectives: To understand pathophysiology, to predict spontaneous outcome, to compare treatment strategies.

2013 IdEx Bordeaux post-doctoral fellowship programme 12 /13

Bernard Mazoyer Email : [email protected] Structural/functional neuroimaging tools for preclinical, clinical and population studies Objective: implement a structural/functional MRI (3T/7T) neuroimaging platform fields dedicated to translational research in the field of age-related disorders and neurodegenerative diseases.

2013 IdEx Bordeaux post-doctoral fellowship programme 13 /13