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Agenda Item # 7 a 10/27‐8/09 ICOC Meeting CIRM Scientific And
Agenda Item # 7 a 10/27‐8/09 ICOC Meeting CIRM Scientific and Medical Research Funding Working Group Biographical information of candidates nominated to serve as Alternate Scientific Members of the Working Group Dr. Michael Boulton, Ph.D. Dr. Boulton is Professor in the Department of Anatomy and Cell Biology at the University of Florida. He received his B.S. degree in Microbiology with Chemistry at the University of Reading, and his Ph.D. from Polytechnic of Central London. He has recently moved to the University of Florida from the University of Texas Medical Branch where he was Director of the AMD Center. Dr. Boulton has a distinguished international record for his investigations into the pathophysiology of the retina. His research group has two main research areas: age‐related changes in the retina and retinal neovascularization. Dr Boulton has a large number of research projects in progress which include nanotechnology to eliminate lipofuscin from the aged eye; investing the contribution of mitochondrial dysfunction and autophagy dysregulation to age‐related macular degeneration; hematopoietic stem cell repair of the damaged retina; targeting γ‐secretase in the regulation of angiogenesis; investigating the role of bone marrow‐derived progenitor cells in vascular repair; and developing new strategies for the regulation of angiogenesis. Dr. Boulton has over 200 publications and has a long history of research support including two current RO1’s. He has given over 40 plenary lectures at international conferences. He currently sits on a number of review committees and is a scientific advisor to a number of other agencies. Dr Boulton is on the editorial board of five international journals and plays a major role in the organization and development of a number of professional societies. -
2011 Gairdner Foundation Annual Report
2011 GAIRDNER FOUNDATION ANNUAL REPORT May 30, 2012 TABLE OF CONTENTS TABLE OF CONTENTS ...................................................................................................................................... 2 HISTORY OF THE GAIRDNER FOUNDATION .............................................................................................. 3 MISSION,VISION ................................................................................................................................................ 4 GOALS .................................................................................................................................................................. 5 MESSAGE FROM THE CHAIR .......................................................................................................................... 6 MESSAGE FROM THE PRESIDENT/SCIENTIFIC DIRECTOR ..................................................................... 7 2011 YEAR IN REVIEW ..................................................................................................................................... 8 REPORT ON 2011 OBJECTIVES ..................................................................................................................... 12 THE YEAR AHEAD: OBJECTIVES FOR 2012 ............................................................................................... 13 2011 SPONSORS ................................................................................................................................................ 14 GOVERNANCE -
Clinical Psychologist
the psychologist vol 28 no 10 october 2015 www.thepsychologist.org.uk Out of this world A special feature takes psychology into alien territory letters 782 what would you say to an alien? 800 news 788 psychology in deep space 804 careers 840 eye on fiction: the alien in us all 808 looking back 816 close encounters 812 Contact The British Psychological Society the psychologist... St Andrews House 48 Princess Road East ...meets Leicester LE1 7DR 0116 254 9568 [email protected] www.bps.org.uk The Psychologist What would you say to an alien? 800 www.thepsychologist.org.uk Jon Sutton talks to Douglas Vakoch, clinical www.psychapp.co.uk [email protected] psychologist and Director of Interstellar Message Composition at the Search for tinyurl.com/thepsychomag Extraterrestrial Intelligence 800 @psychmag ...features Research Digest www.bps.org.uk/digest Psychology in deep space 804 www.twitter.com/researchdigest Nick Kanas considers issues and Advertising countermeasures Reach 50,000 psychologists at very reasonable rates. Eye on fiction: Display Aaron Hinchcliffe The alien in us all 808 020 7880 7661 We asked for your favourite alien [email protected] entity, and what their depiction Recruitment (in print and online says about our own psychology at www.psychapp.co.uk) Giorgio Romano 020 7880 7556 Close encounters of the [email protected] psychological kind 812 Christopher C. French considers September 2015 issue 53,489 dispatched explanations of UFO sightings, alien 804 encounters and even abductions Printed by Warners Midlands plc on 100 per cent recycled ...looks back paper. -
The Molecular Basis of Mecp2 Function in the Brain
Edinburgh Research Explorer The molecular basis of MeCP2 function in the brain Citation for published version: Tillotson, R & Bird, A 2020, 'The molecular basis of MeCP2 function in the brain', Journal of Molecular Biology, vol. 432, no. 6. https://doi.org/10.1016/j.jmb.2019.10.004 Digital Object Identifier (DOI): 10.1016/j.jmb.2019.10.004 Link: Link to publication record in Edinburgh Research Explorer Document Version: Publisher's PDF, also known as Version of record Published In: Journal of Molecular Biology General rights Copyright for the publications made accessible via the Edinburgh Research Explorer is retained by the author(s) and / or other copyright owners and it is a condition of accessing these publications that users recognise and abide by the legal requirements associated with these rights. Take down policy The University of Edinburgh has made every reasonable effort to ensure that Edinburgh Research Explorer content complies with UK legislation. If you believe that the public display of this file breaches copyright please contact [email protected] providing details, and we will remove access to the work immediately and investigate your claim. Download date: 02. Oct. 2021 Review The Molecular Basis of MeCP2 Function in the Brain Rebekah Tillotson 1,2 and Adrian Bird 3 1 - Genetics and Genome Biology Program, The Hospital for Sick Children, The Peter Gilgan Centre for Research and Learning, Toronto, ON M5G 0A4, Canada 2 - Medical Research Council (MRC) Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford, OX3 9DS, UK 3 - Wellcome Centre for Cell Biology, University of Edinburgh, The Michael Swann Building, King's Buildings, Max Born Crescent, Edinburgh, EH9 3BF, UK Correspondence to Adrian Bird: [email protected] https://doi.org/10.1016/j.jmb.2019.10.004 Edited by Tuncay Baubec Abstract MeCP2 is a reader of the DNA methylome that occupies a large proportion of the genome due to its high abundance and the frequency of its target sites. -
Acknowledgment of Reviewers, 2015
Acknowledgment of Reviewers, 2015 The PNAS editors would like to thank all the individuals who dedicated their considerable time and expertise to the journal by serving as reviewers in 2015. Their generous contribution is deeply appreciated. A Peter B. Adler Colin J. Akerman Eric E. Allen James Ammerman Duur K. Aanen Ralph Adolphs Joshua M. Akey Heather C. Allen David M. Amodio Adam R. Abate Ruedi Aebersold Anna Akhmanova Jim Allen Valentin Amrhein John T. Abatzoglou Hugo Aerts Hajime Akimoto Karen N. Allen Esther Amstad Jonathan Abbatt Hagit P. Affek Akin Akinc Michael F. Allen Ronald Amundson Allison Abbott Arash Afraz Shizuo Akira Paul M. Allen Weihua An Jeffrey Abbott Theodor Agapie Ozan Akkus Rosalind J. Allen Zhiqiang An Larry F. Abbott David A. Agard Ivona Aksentijevich Morten Erik Allentoft Laura Diaz Anadon Nicholas L. Abbott Sapan Agarwal Serap Aksoy Stefano Allesina Ganesh Srinivasan Anand Chaouki T. Abdallah Joel W. Ager III Yousef Al-Abed David B. Allison Cort Anastasio Omar Abdel-Wahab Ingi Agnarsson Ashraf Al-Amoudi Steven D. Allison Lefteris Jason Ikuro Abe Anurag A. Agrawal Eric E. Alani Julian M. Allwood Anastasopoulos Stephen Tobias Abedon Ashutosh Agrawal Balbino Alarcón Eric J. Alm Hossain Anawar Moshe Abeles Rakesh Agrawal Qais Al-Awqati Benjamin A. Alman Elissar Andari Asa Abeliovich Jon Ågren Joseph Albanesi Ingvild Almas William R. L. Anderegg John Aber Alan Agresti Francis Albarede Steven C. Almo John M. Anderies Clara Abraham Jeremy J. Agresti Umberto Albarella Douglas Almond Mark L. Andermann John Abraham Jay J. Ague Silas D. Alben Uri Alon Bogi Andersen Daniel A. Abrams Fernan Agüero Frank Alber José M. -
DNA Methylation Patterns and Cancer
restriction/modification system, which brought Werner Arber, Daniel Nathans and Hamilton Smith the 1978 Nobel Prize in Physiology or Medicine, and made restriction enzymes the primary tools of Charles Rodolphe Brupbacher Foundation molecular biology. Four decades have passed since then, but the role of 5-methylcytosine in eukaryotic DNA metabolism is still shrouded in mystery. We know that the sperm methylation pattern is largely The erased after fertilization and that methylation is gradually reintroduced Charles Rodolphe Brupbacher Prize during embryogenesis and differentiation, but the processes that for Cancer Research 2017 regulate the cell type- and tissue-specific methylation patterns remain is awarded to to be elucidated. We have also learned that DNA can be not only methylated, but also demethylated, and that aberrant methylation can lead to disease - including cancer. Again, how these processes are regulated remains to be discovered. However, we have learnt a great Sir Adrian Peter Bird, deal about 5-methylcytosine metabolism during the past three decades and much of our knowledge came from the laboratory of Adrian Bird. PhD Adrian spent his doctoral and postdoctoral time in Max Birnstiel’s for his contributions to our understanding laboratory, first in Edinburgh and then in Zurich, studying the amplification of ribosomal DNA in Xenopus laevis. In this organism, of the role of DNA methylation in genomic rDNA in somatic tissues is highly methylated, while the development and disease extrachromosomal amplicons are unmethylated. When he returned to Edinburgh to establish his own group, Adrian set out to study The President The President of the Foundation of the Scientific Advisory Board the methylation pattern of these loci using the newly-available methylation-sensitive restriction enzymes. -
4 December 2020 Page 1 of 17 SATURDAY 28 NOVEMBER 2020 Already Set up and Ready for Business
World Service Listings for 28 November – 4 December 2020 Page 1 of 17 SATURDAY 28 NOVEMBER 2020 already set up and ready for business. BBC Thai's Chaiyot SAT 06:06 Weekend (w172x7d5fr78h9f) Yongcharoenchai set out to crack the mystery of the self-styled Iranian nuclear scientist killed SAT 00:00 BBC News (w172x5p5kcw9djy) "CIA" food hawkers. The latest five minute news bulletin from BBC World Service. Iran has urged the United Nations to condemn the assassination ‘They messed with the wrong generation’ of its top nuclear scientist, Mohsen Fakhrizadeh, and it's Peru has been in the headlines for having three presidents in a pointed the finger at Israel. We explore how the incoming SAT 00:06 The Real Story (w3cszcnx) week. It’s a story of corruption allegations, impeachment and Biden administration's relationship with its traditional ally will Covid vaccines: An opportunity for science? mass protests, with young people saying their generation has shape regional tensions. had enough of the broken system which their parents put up The rapid development of coronavirus vaccines has heightened with. Ana Maria Roura has been making sense of events for Also on the programme: The number of confirmed coronavirus the hope for a world free of Covid-19. Governments have BBC Mundo. cases in the United States has passed thirteen million, with the ordered millions of doses, health care systems are prioritising pandemic still surging from coast to coast; And a new recipients, and businesses are drawing up post-pandemic plans. Lahore's toxic smog documentary explores Frank Zappa the man, his music, and But despite these positive signs, many people still feel a sense It's the time of year when many Pakistani rice farmers set fire politics. -
Trial Please Esteemed Panel of Researchers
The Biomedical and Life Sciences Collection • Regularly expanded, constantly updated • Already contains over 700 presentations • Growing monthly to over 1,000 talks “This is an outstanding Seminar style presentations collection. Alongside journals and books no self-respecting library in institutions hosting by leading world experts research in biomedicine and the life sciences should be without access to these talks.” When you want them, Professor Roger Kornberg, Nobel Laureate, Stanford University School of Medicine, USA as often as you want them “I commend Henry Stewart Talks for the novel and • For research scientists, graduate • Look and feel of face-to-face extremely useful complement to teaching and research.” students and the most committed seminars that preserve each Professor Sir Aaron Klug OM FRS, Nobel Laureate, The Medical senior undergraduates speaker’s personality and Research Council, University of approach Cambridge, UK • Talks specially commissioned “This collection of talks is a and organized into • A must have resource for all seminar fest; assembled by an extremely eminent group of comprehensive series that cover researchers in the biomedical editors, the world class speakers deliver insightful talks illustrated both the fundamentals and the and life sciences whether in with slides of the highest latest advances academic institutions or standards. Hundreds of hours of thought provoking presentations industry on biomedicine and life sciences. • Simple format – animated slides It is an impressive achievement!” with accompanying narration, Professor Herman Waldmann FRS, • Available online to view University of Oxford, UK synchronized for easy listening alone or with colleagues “Our staff here at GSK/Research Triangle Park wishes to convey its congratulations to your colleagues at Henry Stewart for this first-rate collection of talks from such an To access your free trial please esteemed panel of researchers. -
BBC Radio International Features Catalogue Contents
BBC Radio International Features Catalogue BBC Radio International offers fascinating, thought provoking features that delve into a wide range of subjects, including factual, arts and culture, science and music, in a varied and entertaining way. Noted for their depth of research and authoritative presentation, BBC features give your listeners access to high profile presenters and contributors as they gain a captivating insight into the world around them. You can easily search the BBC features by clicking on the genre under contents. Take a look through the op- tions available and select from hundreds of hours of content spanning from present day back through the last ten years. Have a question or want to know more about a specific genre or programme? Contact: Larissa Abid, Ana Bastos or Laura Lawrence for more details Contents New this month – September 2021 ...........................................................................................................................1 Factual .......................................................................................................................................................................4 Arts and Culture .......................................................................................................................................................26 Music .......................................................................................................................................................................52 Science ....................................................................................................................................................................75 -
The Birth of the Hong Kong Laureate Forum
The Birth of the Hong Kong Laureate Forum On 26 September 2017, I attended the Shaw Prize Award Presentation Ceremony for the first time as Chief Executive of the Hong Kong Special Administrative Region. On that occasion, five distinguished scientists in Astronomy, Life Science and Medicine, and Mathematical Sciences were honoured. They are distinguished individuals who have achieved significant breakthrough in academic and scientific research and whose work has resulted in a positive and profound impact on mankind. As I was then drawing up a multi-pronged strategy to develop innovation and technology in Hong Kong, including the promotion of popular science education, I asked myself how we could bring together this pool of great scientific minds to help nurture the next generation of young scientists. This was the beginning of a year-long endeavour to create the Hong Kong Laureate Forum. I presented prizes at the Shaw Prize Award Presentation Ceremony 2017. From right are Laureate in Astronomy, Professor Simon DM White; Laureate in Life Science and Medicine, Professor Ronald D Vale; Laureates in Mathematical Sciences, Professor János Kollár and Professor Claire Voisin. Another Laureate in Life Science and Medicine, Professor Ian R Gibbons, did not attend the Ceremony. 1 Under the vision and generosity of the late Sir Run Run Shaw and with the unfailing support of his wife the late Lady Shaw, the Shaw Prize was established in 2002 to recognize advances and outstanding contributions in three disciplines, namely, Astronomy, Life Science and Medicine, and Mathematical Sciences. In less than two decades, the Shaw Prize has become a world-renowned award for the highest achievements in mankind. -
Communicating Biochemistry: Meetings and Events
© The Authors. Volume compilation © 2011 Portland Press Limited Chapter 3 Communicating Biochemistry: Meetings and Events Ian Dransfield and Brian Beechey Scientific conferences organized by the Biochemical Society represent a key facet of activity throughout the Society’s history and remain central to the present mission of promoting the advancement of molecular biosciences. Importantly, scientific conferences are an important means of communicating research findings, establishing collaborations and, critically, a means of cementing the community of biochemical scientists together. However, in the past 25 years, we have seen major changes to the way in which science is communicated and also in the way that scientists interact and establish collabo- rations. For example, the ability to show videos, “fly through” molecular structures or show time-lapse or real-time movies of molecular events within cells has had a very positive impact on conveying difficult concepts in presentations. However, increased pressures on researchers to obtain/maintain funding can mean that there is a general reluctance to present novel, unpublished data. In addition, the development of email and electronic access to scientific journals has dramatically altered the potential for communi- cation and accessibility of information, perhaps reducing the necessity of attending meetings to make new contacts and to hear exciting new science. The Biochemical Society has responded to these challenges by progressive development of the meetings format to better match the -
World Service Listings for 8 – 14 May 2021 Page 1 of 16
World Service Listings for 8 – 14 May 2021 Page 1 of 16 SATURDAY 08 MAY 2021 A short walk in the Russian woods Producer: Ant Adeane Another chance to hear Oleg Boldyrev of BBC Russian SAT 01:00 BBC News (w172xzjhw8w2cdg) enjoying last year's Spring lockdown in the company of fallen The latest five minute news bulletin from BBC World Service. trees, fungi, and beaver dams. SAT 05:50 More or Less (w3ct2djx) Finding Mexico City’s real death toll Image: 'Open Jirga' presenter Shazia Haya with all female SAT 01:06 Business Matters (w172xvq9r0rzqq5) audience in Kandahar Mexico City’s official Covid 19 death toll did not seem to President Biden insists US is 'on the right track' despite lower Credit: BBC Media Action reflect the full extent of the crisis that hit the country in the job numbers spring of 2020 - this is according to Laurianne Despeghel and Mario Romero. These two ordinary citizens used publicly The US economy added 266,000 jobs in April, far fewer than SAT 03:50 Witness History (w3ct1wyg) available data to show that excess deaths during the crisis - economists had predicted. President Biden has said his Surviving Guantanamo that’s the total number of extra deaths compared to previous economic plan is working despite the disappointing numbers. years - was four times higher than the confirmed Covid 19 We get analysis from Diane Swonk, chief economist at After 9/11 the USA began a programme of 'extraordinary deaths. accountancy firm Grant Thornton in Chicago. rendition', moving prisoners between countries without legal Also in the programme, Kai Ryssdal from our US partners representation.