Europe -Diagenodes.a.

TECHNICAL DATA SHEET Precautions: Storage: Purity: Specificity: conjugated syntheticpeptidecontaining anaminoacidsequence from thecentral partoftheprotein (1). Description: role inchromatin modification andbeimportant for the regulation oftranscription. a play Therefore,deacetylases.may histone it with and YY1 factortranscription the with interacts and nucleus the to localizes FKBP3 proliferation.T-cell inhibit which immunosuppressants two rapamycin, and FK506 for immunoregulationin cellularbasic and processes involving folding trafficking. and a as acts It receptor FKBP3 (UniProtKB/Swiss-Prot entry Q00688) is a member of the immunophilin , which plays a role Target description Last data sheetupdate: (1)  References: Western blotting ELISA Applications Lot #: Cat. No. Other names:FKBP25,PPIase,Rotamase FKBP3 polyclonal antibody PRODUCT NAME /orders Genomics, Prof. A.F. Stewart, TUDresden, Tatzberg 47/49,01307Dresden, Germany Peptide design by Andrea Kranz, Western blot analysis by Heike Petzold and Andrea Kranz, BIOTEC, Dept. of Whole antiserumfrom rabbit containing 0.05%azide. A373-004 @ Store at-20°C;for long storage, store at-80°C.Avoid multiple freeze-thaw cycles. diagenode.com /info C15310109 Mouse:positive Other species:nottested Polyclonal antibody raised in rabbit against mouse FKBP3 (FK506 Binding Protein 3), using a KLH- Thisproduct isfor research useonly. Notfor useindiagnostic ortherapeutic procedures. (CS-109-100) April7,2010 @ diagenode.com // 1:500 1:100 –1:200 Suggested dilution Source: Type: North America -Diagenode Inc. Polyclonal Rabbit /orders.na References Concentration: Size: Fig 2(1) Fig 1 @ diagenode.com /techsupport.na 100μl notdetermined www.diagenode.com @ diagenode.com Europe -Diagenodes.a.

TECHNICAL DATA SHEET estimated to be1:5,400. was antibody the of titer the 1), (Figure dilution antibody the against absorbance the plotting By rabbit. the of directed antibody immunization for used Diagenode peptide the with the coatedwere plates The of CS-109-100). No. dilution (Cat. FKBP3 mouse serial against a using performed was ELISA an titer, the determine To Determination ofthetiter Figure 1 (expected size:25kDa)isindicated ontheright. interest BSA/ of protein the of location in the left; the 1:500 on shown is diluted kDa) (in marker weight CS-109-100), molecular PBS-Tween.The No. (Cat. FKBP3 mouse against antibody Diagenode the with (E14Tg2a) cells stem embryonic and fibroblasts (NIH3T3) frommouse lysatescell whole on performed Westernwas blot Western blot analysis usingtheDiagenodeantibodydirected against FKBP3(1) Figure 2 /orders @ diagenode.com /info @ diagenode.com // North America -Diagenode Inc. /orders.na @ diagenode.com /techsupport.na www.diagenode.com @ diagenode.com