High Leverage. Strong Impact. The New Hampshire Innovation Research Center

The NHIRC matches businesses in New Hampshire with dollars to support translational research efforts that further growth and development of New Hampshire businesses, increasing job growth, opportunities, and revenues. The NHIRC was legislated in 1991, Title 15 Chapter 187A.

NHIRC Highlights

650 jobs created or retained

1 $394,407 20:1 total leverage for state funds

$32MM SBIR awards for NHIRC projects

$25MM in additional federal funding for NH educational 3 $112,776 institutions through EPSCoR $39,999 2 $570,126 Awardees have raised over $870,346 $3,476,521 5 $900MM in additional $322,696 funding creating many 7 6 marketed products $69,540 8 $890,326 15 17 4 $2,560,220 21 16 Questions? 10 20 $2,231,058 $106,592 23 24 Contact Tim Willis at 9 14 9 $840,228 11 18 1 22 [email protected]; $73,996 12 13 $1,158,462 603.862.0948 $881,651 $509,921 $656,863 $1,177,479 $1,997,919 $20,059 $428,854 $790,956

The NHIRC Oversight Committee 2015 These positions are legislated or appointed by the NH Governor.

NH Senate Martha Fuller Clark, Senator NH House of Representatives *Open NH Dept. of Economic Development Christopher Way, Interim Director, Division of Economic Development NH School of Law, UNH John Orcutt, Professor of Law Large Businesses Robert Gyurik, Pharmaceutical Consultant Large Businesses Richard Powers, VP and Deputy General Manager, BAE Systems Small Businesses Jenny Houston, VP of Business Development, Warwick Mills Senior Vice Provost for Research, UNH Jan Nisbet, Senior Vice Provost for Research College of Engineering and Physical Science, UNH Glenn Shwaery, Associate Dean for Research New Hampshire Innovation Research Center Marc Sedam, Executive Director Districts 1, 2, 3, 6, 7 NHIRC Proposal Dollars

District 1 Senator Jeff Woodburn $394,407 2001 Presby Environmental Inc. Sugar Hill 1997 Crown Vantage Berlin 1995 NE Electric Wire Lisbon

District 2 Senator Jeanie Forrester $39,999 1995 L.W. Packard Ashland

District 3 Senator $112,776 1 2006 MBP, Bioenergy, LLC North Conway 1995 Morrell Corp. Glen

District 6 Senator Sam Cataldo $870,346 2010 Albany Engineered Composites, Inc. Rochester 2009 Albany Engineered Composites, Inc. Rochester 3 2008 Newport Computer Services Rochester 2002 Lydall, Inc. Rochester 2 2001 Albany Techniweave, Inc. Rochester (now Albany Engineered Composites) 1999 Albany Techniweave, Inc. Rochester 6 7 (now Albany Engineered Composites 1999 Zero Emissions New Durham 1994 Cleary Cleaners Rochester

District 7 Senator Andrew J. Hosmer $570,126 2002 AavidThermalloy, LLC Laconia 2001 AFL (Noyes Fiber Systems) Belmont 2001 AFL (Noyes Fiber Systems) Belmont 1995 Aavid Engineering Laconia (now AavidThermalloy, LLC) 1993 Allan-Rogers Ltd. Laconia 1993 Mills Industries Laconia

AavidThermalloy, Laconia, NH (‘95, ’02) “We entered the new market area of heat pipes through a NHIRC grant by working with UNH chemical engineering professor to study the corrosion and aging to improve the reliability of these heat pipes. UNH had equipment not available at Aavid and the expertise needed to develop a predictive aging model. Aavid officials estimated this market to produce between $500,000 and $1 million within the following year, and add about eight new jobs.” ~ Craig Wood, CEO Albany Engineered Composites, Inc., Rochester, NH (‘99, ’01, ‘09, ‘10) “The technology developed in this project will allow us to broaden AEC’s markets by expanding the range of components that can be fabricated using 3D weaving and resin transfer molding. While these technologies are relatively new, they are being used in some major programs, such as the CFM LEAP-X engineer program, and the landing gear braces for the new Boeing 787 Dreamliner. For growing, leading technology companies like AEC, it is crucial to be able to participate in high risk-high impact research through NHIRC. It should also be noted that NHIRC funding is also crucial for UNH in providing its faculty and students the opportunity to work on cutting-edge research in collaboration with the industry, thereby providing the next generation of engineers and scientists who will continue to grow the economy of our State.” ~ Jon Goering, Divisional Chief Technology Officer

Did you know… Albany Engineered Composites (‘99, ’01, ‘09, ‘10) has moved its global headquarters to Rochester, NH. Albany employs 6,200 people worldwide.

Presby Environmental (‘01) is an innovative environmental organization that engineers new technology to change the way the world approaches wastewater treatment. Today the company is working at the cutting edge of water pollution control to help protect and preserve our most precious natural resources. Districts 4, 16, 17, 18

NHIRC Proposal Dollars

District 4 Senator David H. Watters $890,326 2014 Turbocam, Inc. Barrington 2006 Turbocam, Inc. Barrington 2005 Prometheus Group Dover 2001 Textron Automotive Co. Dover 2000 Turbocam, Inc. Barrington 1997 Conproco Dover 1996 Eastern Air Devices Dover (now Electrocraft) 1994 Energy Reclaimation Inc. Rollinsford 1994 GFS Magnetics Dover 1993 Eastern Air Devices Dover

District 16 Senator David Boutin $20,059 2007 Omega Smart, Inc. Candia

District 17 Senator John Reagan $322,696 2005 Sentry BioScience Inc. Nottingham 2004 Pleasant View Gardens Loudon 4 17 2002 Pleasant View Gardens Loudon 16 1998 Poly Roll Loudon 18 1998 Great Crates Strafford

District 18 Senator Donna M. Soucy $790,956 2011 Velcro Group Corporation Manchester 2009 Velcro Group Corporation Manchester 2008 Velcro Group Corporation Manchester 2001 Poly Vac Inc. Manchester 1999 Insight Biomedical, Inc. Manchester 1997 Hubscrub Manchester 1994 KRL/Bantry Manchester

Velcro, Manchester, NH (‘08, ‘09, ‘11) “The NHIRC eased Velcro’s transition to collaborative interaction with UNH by matching their investment and thereby doubling their investment’s impact. Our project is aimed at developing new fastening technologies based on nanoscale structures developed at UNH (i.e., new nanotechnologies). Velcro is likely to utilize this developing technology for years to come to produce next generation fastening products. This would favorably impact NH’s economy by increasing manufacturing jobs, not to mention corporate tax revenues.” ~ Glen Miller, Principal Investigator Pleasant View Gardens, Loudon, NH (‘02, ‘04) “We are the largest wholesale nursery in New Hampshire and a founding partner in Proven Winners, the #1 nationally recognized consumer brand of gardening plants. Nine of the developed varieties, developed through the NHIRC project have been patented. Increased sales of these breeding lines have yielded higher profits for our company.” ~ Henry Huntingdon, Founder

Did you know... Pleasant View Gardens (‘02, ‘04) has researched, experimented with and grown millions of plants, selecting the very healthiest and hardiest assortments. The company has become an industry pioneer in energy and labor savings. District 5

NHIRC Proposal Dollars

District 5 Senator David Pierce $3,476,521 2014 Peroxyium Lebanon 2011 M2S, Inc. West Lebanon 2011 AxiSol Lebanon 2010 Celdara Medical, LLC Lebanon 2009 Hypertherm, Inc. Hanover 2009 ImmuRx Inc. Lebanon 2009 M2S, Inc. West Lebanon 2009 Ray-Tech Infrared Corporation Charlestown 2008 Woomera Therapeutics Lebanon 2008 Celdara Medical, LLC Lebanon 5 2007 ImmuRx Inc. Lebanon 2007 AAC International Lebanon 2004 Medical Media Systems West Lebanon 2003 ThermalVision Inc. Hanover 2003 GlycoFi, Inc. (now Merck) Lebanon 2001 AAC International Lebanon 1999 Aurora Optics Lebanon 1998 Audit Security Bags West Lebanon 1998 Fluent, Inc. Lebanon 1996 Materials Innovations Lebanon 1992 Medical Media Systems West Lebanon

Celdara Medical, Lebanon, NH (‘08, ‘10) “Without our first NHIRC award we may not have been able to raise angel funding in such a difficult economic climate, we would not have a CLIA-certified lab in which to develop and bring to market a diagnostic/prognostic/predictive test for patients with scleroderma. Without it, we may have had to close our doors, or more likely, we may well have opened our doors in VT or MA.” ~ Jake Reder, CEO

ImmuRx Inc., Lebanon, NH (‘07, ‘09) “An IRC grant catalyzed the start of ImmuRx, Inc., a biotechnology company. It got us started with a grant of $69,000. We have since raised over $5,000,000, hired skilled workers and moved our cancer treatment toward commercialization. We are on target to keep growing.” ~ David Delucia, CEO

Did you know...

Celdara (‘08, ‘10) has created a CLIA-certified diagnostic/prognostic/predictive test for patients with scleroderma.

GlycoFi (‘03) was founded in 2000 with the mission of dramatically improving the capacity and cost of producing human therapeutic proteins, while simultaneously enhancing their efficacy and safety as therapeutics. GlycoFi was acquired by Merck in 2006 for $400MM. Districts 8, 9, 10, 15, 20

NHIRC Proposal Dollars

District 8 Senator Gerald Little $69,540 2001 Hexaport International Ltd. Weare 1998 Northland Tool Weare District 9 Senator $881,651 2007 Graphicast Inc. Jaffrey 2006 IXXAT, Inc Bedford 2006 IXXAT, Inc Bedford 2004 Spaceflight Systems Corporation Bedford 2002 New Hampshire Ball Bearing, Inc. Peterborough 2001 D.D. Bean / Sons Jaffrey 1999 Aura Instrumentation Mount Vernon 1998 Creative Optics Bedford 1997 Pegit, Inc. Dublin 1997 Sonetech Corp. Bedford 8 1995 Biorelease Technologies Bedford 15 1992 Paragon Publishing Bedford 20 10 District 10 Senator Molly Kelly $106,592 9 2009 Roy Matheson and Associates Keene District 15 Senator $73,996 2007 Nanocomp Technologies, Inc. Concord 2000 Allor Project Company Concord District 20 Senator Lou D’Allesandro $0

Roy Matheson and Associates, Keene, NH (‘09) “This research project developed a bridge between the Electrical and Computer Engineering and the Occupation Therapy Departments at UNH and created student interest by applying their knowledge to evaluate and enhance the equipment used to perform functional capacity evaluations (FCE) for Heart Rate Monitors, Blood Pressure Monitors, and Load Cells.” ~ John LaCourse, UNH Professor of Electrical and Computer Engineering

Graphicast, Inc., Jaffrey, NH (‘07) “The NHIRC project improved an existing process to make it more efficient. This helped to improve production rates, improve quality, and increase capacity.” ~ Val Zanchuk, President

Did you know... IXXAT (‘06) is one of the leading suppliers of data communication technology for the automation and automotive industry with a continual and considerable amount of investment in research and development of innovative, powerful and cost effective products and constant training for our employees to insure their familiarity with the latest technological advancements. Districts 11 & 12 NHIRC Proposal Dollars

District 11 Senator Gary Daniels $1,997,919 2015 Nanocomp Technologies, Inc. Merrimack 2013 AIRMAR Technology Milford 2011 Hitchiner Milford 2006 Cubic Wafer Merrimack 2006 Percardia Inc. Merrimack 2005 Cubic Wafer Merrimack 2005 GT Equipment Technologies, Inc. Merrimack 2004 GT Equipment Technologies, Inc. Merrimack 2002 GT Equipment Technologies, Inc. Merrimack 2002 GT Equipment Technologies, Inc. Merrimack 2001 Norton-Saint Gobain Industrial Ceramics Milford 2000 GT Equipment Technologies, Inc. Merrimack 1999 GT Equipment Technologies, Inc. Merrimack 1998 FPR, Inc. Merrimack 1998 Sanders Merrimack 1996 AIRMAR Technology Milford 1994 Clearview Software Amherst 1994 Saint-Gobain Crystals Milford

District 12 Senator Kevin Avard $656,863 2012 New Hampshire Optical Systems Nashua 11 2011 Advanced Renewable Energy Company LLC Nashua 12 2006 Warwick Mills New Ipswich 2004 Advanced Computer Resources Nashua 2001 Northeast Photosciences Hollis 1994 Flight Simulation Systems Nashua 1994 Nashua Corp Nashua

New Hampshire Optical Systems, Nashua, NH (‘12) “As a telecommunications provider of fiber optic infrastructure solutions, our NHIRC award allows us to research software-defined networks that offer increased broadband speeds and capabilities to businesses of all sizes across the state. The anticipated result is that we will be able to bring network technology to broadband companies who want to expand Internet and communication products to under-served and un-served areas in New Hampshire.” ~ Rob Carmichael, President

Warwick Mills, New Ipswich, NH (‘06) “Warwick worked on a project with Dartmouth to advance materials for medical applications. The NHIRC grant positioned us to secure $150,000 in National Science Foundation funding and a new federal grant has the potential to secure an additional $500,000 later this year. This means jobs for Warwick and jobs for New Hampshire.” ~Jenny Houston,VP of Business Development

Did you know...

Hitchiner (‘11) is the premier supplier of complete-to-print, high-volume, complex thin-wall investment castings and fully-finished casting components to industry. Hitchiner has over 2,000 employees worldwide and revenues of $200MM.

AIRMAR Technology Corporation (’96, ’13), a NH small business formed in 1982, is a designer and manufacturer of marine electronics, and has had steady growth in business volume and size. Nearly 100% of AIRMAR’s products are designed and built in NH and construction of a second manufacturing building began in Fall 2012. Districts 13, 14, 19, 22

NHIRC Proposal Dollars District 13 Senator Bette R. Lasky $428,854 2007 Sky Skan, Inc. Nashua 2000 Resonetics, Inc. Nashua 1998 Lancast Nashua District 14 Senator Sharon M. Carson $1,177,479 2011 Conductive Compounds Hudson 2009 Presstek Inc. Hudson 2007 Presstek Inc. Hudson 2002 Durham Research Londonderry 2001 Durham Research Londonderry 2000 Diatide Londonderry 1997 Acu-Gage Hudson 1997 Admix Londonderry District 19 Senator $509,921 1999 Johnson / Johnston Associates Hampstead 1995 Built-On Technology Derry 1993 Fireye Derry District 22 Senator $1,158,462 2011 Design Mentor, Inc. Pelham 2007 AmberWave System Corporation Salem 14 2001 Chart Inc., Storage Systems Division Plaistow 19 2001 Ion Physics Corporation Atkinson 22 13 1998 Process Engineering, Inc. (now Chart Inc.) Plaistow 1997 Advanced Device Technologies Salem 1993 Bioquest Atkinson 1993 Global Ozone Solutions Atkinson

Conductive Compounds, Hudson, NH (‘11) “The fact that a small business in the state of New Hampshire was able to join forces with a small group of researchers at a state university to participate in what is considered the current “holy grail” of material science and commercialization is extraordinary. My company employs 13 people, we are currently hiring three more and have sustained double digit growth over the past three years despite the economy. We have sales offices throughout Europe, Israel, Russia and in three key areas in Asia. Research into nanopartical metals was way beyond the scope of a small business like mine, but with the NHIRC matched funding and the resources at UNH, we will end with a commercially viable means to manufacture and sell specialty inks and coatings.” ~ Don Banfield, CEO Design Mentor, Inc., Pelham, NH (‘11) “We view our current NHIRC award as THE critical link between our internal investment in the VentriFlo technology and having it further supported by a combination of SBIR grants and Corporate Sponsorships. l wish I had known of the NHIRC Match Grant process several years ago. It provides access to critical resources at a tenuous point in technology development that are very difficult to afford any other way. The award is, in essence, a very important “multiplier” to our efforts.” ~ Doug Vincent, President and CEO Sky Skan, Nashua, NH (‘07) “This NHIRC project ‘Climate and Change’ visualization for immersive Full Dome Environments allowed us to find new ways of making NOAA data products more widely accessible with an immediate value of helping the public understand meteorological and ocean current concepts.” ~ Colin Ware, UNH Data Visualization Lab

Did you know… At Sky Skan’s world headquarters in Nashua (’07) they design and install the world’s top full-dome planetariums and visualization theaters which are in use at world-renowned institutions such as Cunard’s Queen Mary 2 (the only planetarium at sea) and the Smithsonian Institution’s National Air and Space Museum.

District 21 NHIRC Proposal Dollars

District 21 Senator Martha Fuller Clark $2,560,220 2015 Lamprey Networks, Inc. Durham 2014 ArgenTech Solutions Durham 2014 Lamprey Networks, Inc. Durham 2014 2KR Systems, LLC Barrington 2013 Obliterase Portsmouth 2012 Hutchinson Sealing Systems Newfields 2012 ArgenTech Solutions Durham 2011 Innovacine Portsmouth 2011 Unified Office Portsmouth 2009 Simply Green Biofuels, LLC Portsmouth 2009 Applied Geosolutions, LLC Durham 2008 Spin Analytical Inc. Durham 2007 IVS 3D Portsmouth 2006 White Mountain Pharma, Inc. Portsmouth 2006 Xemed Durham 2005 Regal Sleeving and Tubing, LLC Newmarket 2005 Chaoticom Technologies Durham 2004 Great Bay Aquaculture/Aquafarms Portsmouth 21 2004 Regal Sleeving and Tubing, LLC Newmarket 2003 Powerspan (now Zero Emissions, Inc.) Portsmouth 2001 Intellitech Corporation Durham 2001 WASTECH International, Inc. Portsmouth 1998 Fenris Durham 1997 Piscataqua Research Portsmouth 1994 Current Technology Durham ArgenTech Solutions, Durham, NH (‘12, ‘14) “Many industrial, automotive, military, and manufacturing markets need new solutions to ensure safety in case of a lack or loss of power. This innovation will bring improved protection for workers and offers energy-saving lighting alternatives in sight-limiting environments. The partnership with UNH allows us access to specialized equipment and research knowledge, the assistance of talented UNH students to hone organic talent, and an environment in which to test our products before commercialization.” ~ Russell Mason, VP Marketing & Sales and CIO

Xemed, Durham, NH (‘06) “A breakthrough in medical imaging, achieved through funding from the IRC, has also been the catalyst for acceleration of commercial success for Xemed. Xemed recently received a contract to develop its imaging technology from a major pharmaceutical company. Several research hospitals world wide are lining up to acquire Xemed’s recently announced xenon polarizer product. Each sale will produce close to $1MM in revenue. Many states have state-funded mechanisms to attract and support small technology businesses. Xemed would not have achieved its present trajectory with out grant assistance from the IRC.” ~ William Hersman, CEO and Founder

Did you know...

Applied GeoSolutions (’09) was formed in 2000 to promote, support and provide scientifically sound cutting- edge geo-spatial technologies, biogeochemical models and integrated spatial information services for greenhouse gas (GHG) emission, ecosystem modeling, and agricultural and forestry management.

Hutchinson Sealing Systems (’12) manufactures vehicle weather strips for cars, trucks, and RVs as well as engineered seals used for HVAC systems, computer cabinets, and other containers. Hutchinson is known for innovation with over 200 engineers and scientists dedicated solely for this purpose with proven innovation in materials, process and product. Districts 23 & 24 NHIRC Proposal Dollars

District 23 Senator Russell Prescott $840,228 2008 Recycled Asphalt Brentwood 2007 Alaka’I Consulting / Engineering Inc. Chester 2007 BioSignetics Corporation Exeter 2006 BioSignetics Corporation Exeter 2002 SiGARMS, Inc. Exeter 1995 Dedicated Electronics Chester

District 24 Senator Nancy F. Stiles $2,231,058 2011 Itaconix, LLC Hampton Falls 2009 Itaconix, LLC Hampton Falls 2009 The Timberland Company Stratham 2009 Kensington Research Hampton Falls 2008 Kensington Research Hampton Falls 2008 Foss Manufacturing Company Hampton 2008 Itaconix, LLC Hampton Falls 2005 Ardent Seabrook 2005 Bentley Pharmaceuticals North Hampton 2005 Process Instrumentation, lnc. Hampton 24 23 2003 Wireless Sensors, LLC Greenland 2003 Bentley Pharmaceuticals North Hampton 2002 Bentley Pharmaceuticals North Hampton 2001 Bentley Pharmaceuticals North Hampton 2001 Bentley Pharmaceuticals North Hampton 2000 Bentley Pharmaceuticals North Hampton 2000 Bentley Pharmaceuticals North Hampton 1999 BioTherapeutics, LLC Stratham 1998 BioTherapeutics, LLC Stratham 1996 SleepNet Corp. Hampton

Itaconix, Hampton Falls, NH (‘08, ‘09, ‘11) “Our privately-held green technology company founded in 2008 develops polymers that are derived from renewable resources and that replace the petroleum-based chemicals used in products such as detergents. Our company has demonstrated remarkable growth and in 2009 announced the commercial launch of its first two products. Most recently, we have filed 5 patents related to our NHIRC projects.” ~ John Shaw, CEO and Co-Founder Foss Manufacturing, Hampton, NH (‘08) “The IRC award allowed us to carry our analytical work and gain the understanding needed to optimize the processing of an antimicrobial agent into a polymer. At the same time we worked in parallel with the FDA to gain FDA clearance on the safety and efficacy of the technology. The recent FDA clearance and ongoing process optimization, developed in part through this research program, will help us to attain more sales.” ~ Jacqueline Traynor, Director of Research & Product Development

Did you know... SleepNet (‘96) created a sleep mask “MiniMe” which has been approved by the FDA for pediatric use—the only true gel cushion, one-of-a-kind mask for kids. Itaconix (’08, ‘09, ‘11) is a green technology company developing,manufacturing and marketing environmentally friendly polymers derived from renewable resources. The company has hired 12 employees in the past two years alone. Bentley Pharmaceuticals (‘00, ‘01, ‘02, ‘03, ‘05) was sold to Teva Pharmaceuticals for $360MM in March 2008. It created a spin-off, CPEX Pharmaceuticals, in that transaction which was sold for $72MM in April 2011. COOS1 $317,332

$3,472,689 GRAFTON2 CARROLL $112,776

BELKNAP23 $570,126

$72,535 SULLIVAN5 MERRIMACK15 STRAFFORD22 $3,687,093

ROCKINGHAM14 CHESIRE8 HILLSBOROUGH13

$181,791 $6,431,744

$5,586,414 $283,248

The NHIRC Proposal Dollars by County