Canine anaplasmosis Canine Canine ehrlichiosis

® Canine granulocytic anaplasmosis is caused by WhatWhat to to do do with with your yourSNAP SNAP Anaplasma® result Canine ehrlichiosis is caused by the bacteria (transmitted by the and Ehrlichia test results the bacterium Anaplasma phagocytophilum brown dog tick) and (transmitted by the lone star tick). Canine

(transmitted by the deer tick or black-legged tick). Positive result Negative result Ehrlichia infections may progress to the subclinical phase, lasting days, months, Anaplasma platys (transmitted by the brown dog tick) The dog has been exposed and may be infected Exposure is unlikely or years. is the cause of infectious cyclic . Did you know? Ehrlichia canis Ehrlichia ewingii Check for hematologic abnormalities (CBC and/or • Review benefits What to • Dogs coinfected with E. canis and Primary vector Did you know? blood film) and changes in serum biomarkers; perform a of tick prevention do next? • Many mammalian species, including humans, are susceptible complete chemistry panel that includes the IDEXX SDMA Test • Retest in 1 year A. platys were found to have more Rhipicephalus sanguineus Amblyomma americanum (brown dog tick) (lone star tick) to A. phagocytophilum infection. severe anemia and thrombocytopenia than dogs with either single infection.9 • Dogs coinfected with Anaplasma and other bacterial pathogens Pathology Clinical signs Clinical signs may have more complex disease presentations and respond • In a study of healthy dogs with Infects Infects granulocytes and/or laboratory and/or laboratory Diagnose* to E. canis, 39% were more slowly to therapy. findingsDO support findingsDO NOT support Clinical presentation anaplasmosis/ehrlichiosis anaplasmosis/ehrlichiosis thrombocytopenic.10 • A. platys infects canine and is frequently seen as a • , anorexia, lethargy • Fever, anorexia, lethargy • disorders • Polyarthritis, lameness coinfection with Ehrlichia canis. • Chronic E. canis infections, if left • Polyarthritis, lameness • Neurological signs untreated, can lead to bone marrow Not generally • Lymphadenomegaly Treat Doxycycline/tetracycline dysfunction or kidney disease. Anaplasma recommended • Neurological signs phagocytophilum Anaplasma platys • Dogs with Ehrlichia antibodies in Laboratory abnormalities Primary vectors E. canis endemic areas had a 300% • Anemia • Thrombocytopenia Ixodes scapularis Most likely Rhipicephalus Evaluate clinical response increased risk of developing chronic • Thrombocytopenia • Increased IDEXX SDMA Test Ixodes pacificus sanguineus (brown dog tick) and CBC in 1 week; if kidney disease (CKD).3 • Hyperglobulinemia >14 µg/dL (deer tick or black-legged tick) no improvement, pursue • Proteinuria other diagnosis Pathology Monitor Note Infects neutrophils Infects platelets Previous infection may not prevent reinfection, and 10,11 Clinical presentation Perform annual minimum database, including persistent infections are possible. complete chemistry that includes the IDEXX SDMA Test, Can present acutely: Usually minimal clinical signs, CBC, and complete urinalysis • Fever but some dogs may have: • Anorexia • Fever • Lethargy • Uveitis • Polyarthritis, lameness • and ecchymoses Evaluate tick prevention strategies and reinforce Prevent • Neurologic signs • Epistaxis value of year-round protection Laboratory abnormalities *Additional diagnostics may be beneficial. See the “Serology and PCR • Thrombocytopenia • Thrombocytopenia for sick patients” section of this guide for more information. • Lymphopenia • Increased liver enzymes

Note © 2017 IDEXX Laboratories, Inc. All rights reserved. • 09-69074-05-EHR All ®/TM marks are owned by IDEXX Laboratories, Inc. or its affiliates in the United States and/or other countries. Previous infection may not prevent reinfection and The IDEXX Privacy Policy is available at idexx.com. persistent infections are possible.7,8