Recombinant CTBP2 Catalog No: 81251, 81951 Quantity: 50, 1000 µg Expressed In: E. coli Concentration: 1.1 µg/µl Source: Human Buffer Contents: Recombinant CTBP2 protein is supplied in 25 mM Tris-HCl pH 8.0, 500 mM NaCl, 10% glycerol, 0.5 mM TCEP.

Background: CTBP2 (C-Terminal Binding Protein 2), also written as CtBP2, is a protein that binds to the C-terminus of adenovirus E1A . It ubiquitously expresses with 2 higher level in heart,skeletal muscle,pancreas,associating to adenovirus E1A,C terminal proteins,involved with and E2F3 in transcription repression. CTBP2 is a targeting diverse transcription regulators. It functions in brown adipose tissue (BAT) differentiation (By similarity). CTBP1 produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. This product is isoform1. CTBP2 and another C-Terminal Binding Protien, CTBP1 can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development.

Protein Details: Recombinant CTBP2 protein was expressed in E.coli as the full length protein (accession number NP_001320.1) with an N-terminal 6×His tag. The molecular weight of the protein is 52.5 kDa. Recombinant CTBP2 protein Application Notes: This product was manufactured as described in Protein Details. 10% SDS-PAGE Coomassie staining Where possible, Active Motif has developed functional or activity assays for MW: 52.5 kDa recombinant proteins. Additional characterization such as enzyme kinetic activity assays, inhibitor screening or other biological activity assays may not have been Purity: >90% performed for every product. All available data for this product is shown.

Storage and Guarantee: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.

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