Transfemoral Aortic Valve Implantation Using the Reverse X-Ray Image in a Patient with Dextrocardia Situs Inversus
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NEW INNOVATION INTERVENTIONS FOR VALVULAR DISEASE AND HEART FAILURE Asia Intervention 2018;4: 41-44 Transfemoral aortic valve implantation using the reverse X-ray image in a patient with dextrocardia situs inversus Tomohiro Kawaguchi*, MD; Shinichi Shirai, MD; Hiroyuki Jinnouchi, MD; Kenji Ando, MD Department of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan KEYWORDS Abstract A frail 94-year-old man, who had dextrocardia situs inversus and symptomatic severe aortic stenosis, • aortic stenosis underwent transcatheter aortic valve implantation (TAVI) using the femoral approach. Computed tomo- • conduction graphy showed that there were no other cardiovascular malformations. Generally, it was difficult to main- abnormalities tain awareness of the position between his heart and ascending aorta during the procedure because of the • femoral inversion of these structures. Therefore, the reverse X-ray image was used to facilitate TAVI, and the pro- • TAVI cedure was successful without complications. However, nine days after TAVI, he developed complete atrio- ventricular block that was symptomatic. Therefore, he underwent cardiac pacemaker implantation using the reverse X-ray image to help position the atrial and ventricular leads. DOI : 10.4244/AIJ-D-17-00047 *Corresponding author: Department of Cardiology, Kokura Memorial Hospital, 3-2-1 Asano, Kokurakika, Kitakyushu, 802-0001, Japan. E-mail: [email protected] © Europa Digital & Publishing 2018. All rights reserved. SUBMITTED ON 31/10/2017 - REVISION RECEIVED ON 15/01/2018 - ACCEPTED ON 17/01/2018 41 Asia Intervention Abbreviations CT demonstrated suitable iliofemoral arteries without stenosis AS aortic stenosis or calcification that could be used as an access route. Our Heart AVB Team concluded that he was a candidate for transfemoral TAVI, atrioventricular block 2018;4: CT computed tomography because of his advanced age and frailty despite an intermediate PMI pacemaker implantation surgical risk (logistic EuroSCORE 13.6% and Society of Thoracic 41-44 SVC superior vena cava Surgeons score 7.2%). TAVI transcatheter aortic valve implantation The procedure was performed under general anaesthesia. An 18 Fr Edwards arterial expandable sheath (Edwards Lifesciences, Introduction Irvine, CA, USA) was inserted from the left femoral artery. All Transcatheter aortic valve implantation (TAVI) is increasingly procedures except for vessel puncture and sheath insertion were used in patients who have symptomatic aortic stenosis (AS) and performed using the reverse X-ray image (Figure 2). A pacing wire have a high risk for an invasive operation or contraindications for was inserted from the right femoral vein, and the tip was located in surgery1,2. Generally, it is difficult to perform any cardiovascular the right ventricle. A 0.035-inch super-stiff wire (Amplatz Extra- interventions in patients with dextrocardia situs inversus, because Stiff Wire; Cook Medical, Bloomington, IN, USA) was passed this condition is rare and makes it difficult to understand the rel- through the aortic valve. Balloon aortic valvuloplasty was per- ative anatomical locations of the heart and great vessels. There formed with a 23 mm balloon (Edwards Lifesciences) under rapid have been few reports of TAVI in patients with dextrocardia situs pacing. The NovaFlex+ Delivery System (Edwards Lifesciences) inversus. We report a patient with dextrocardia situs inversus who was inserted into the expandable sheath after a 180° rotation underwent TAVI and then required pacemaker implantation (PMI) so that the Edwards logo pointed downwards. This allowed the due to delayed onset complete atrioventricular block (AVB). delivery system to pass smoothly through the inverted aortic arch (Figure 3). A 26 mm Edwards SAPIEN XT valve (Edwards Methods and results Lifesciences) was implanted under rapid pacing. After valve A 94-year-old man who had dextrocardia situs inversus was implantation, aortography and transoesophageal echocardiography referred to our hospital with recurrent syncope. His medical his- showed an excellent valve position without aortic regurgitation. tory included congestive heart failure, hypertension and demen- At nine days after TAVI, the patient suddenly presented com- tia. The electrocardiogram showed sinus rhythm and first-degree plete AVB. CT before TAVI showed a left-sided superior vena AVB without bundle branch block. Echocardiography showed cava (SVC) draining into the right atrium and no other struc- a heavily calcified aortic valve with a mean gradient of 46 mmHg, tural malformation such as persistent left SVC. Again using the normal left ventricular systolic function and no other significant reverse X-ray image during the procedure so that the anatomical valvular disease. Coronary angiography revealed no significant orientation could be understood and the procedure performed with stenosis. In addition, computed tomography (CT) showed dex- the usual image, the atrial and ventricular leads of a permanent trocardia (Figure 1), which consisted of a right-sided aorta and pacemaker were successfully implanted into the right atrium and left-sided inferior vena cava. CT also showed an aortic annulus ventricle through the right subclavian vein. Eventually, he was dis- area of 416 mm2 and a mean diameter of 23 mm. Furthermore, charged without any further events after TAVI. Figure 1. Computed tomography. A) Right-sided left ventricle and descending aorta. B) 3D image of the right-sided aortic arch. CRA: cranial oblique; LAO: left anterior oblique 42 TAVI in a patient with dextrocardia Asia Intervention 2018;4: 41-44 Figure 2. X-ray image. A) Sheath insertion using a normal X-ray image. B) Deployment of a 26 mm Edwards SAPIEN XT valve using the reverse X-ray image. Figure 3. NovaFlex+ Transfemoral Delivery System. In normal usage, (A) the Edwards logo faces upwards (red arrow) and (B) the delivery system flexes to the left. In this case, (C) the Edwards logo was rotated 180° (yellow arrow), so that (D) the delivery system flexed to the right and passed through the right-sided aortic arch. 43 Asia Intervention Discussion TAVI. In cases of dextrocardia without other cardiovascular mal- To our knowledge, this is the first reported case of dextrocardia formations, insertion of the NovaFlex+ Delivery System into the situs inversus to have TAVI using the reverse X-ray image. expandable sheath after 180° rotation and the reverse X-ray image 2018;4: Dextrocardia is a very rare congenital heart disease. A previous are important in order to perform TAVI successfully. Theoretically, study reported that the incidence of dextrocardia is about one in these methods can be applied when the Commander delivery sys- 3 41-44 12,000 live births . Dextrocardia is often associated with various tem and Edwards SAPIEN 3 valve (Edwards Lifesciences) are structural malformations such as univentricular heart and bilateral used. SVC3. In this case, CT revealed a simple mirror image dextrocar- dia without other structural heart disease. There are few reports of Impact on daily practice TAVI in patients with dextrocardia situs inversus4,5. Dubois et al Insertion of the NovaFlex+ Delivery System into the expand- reported that an 84-year-old woman with situs inversus totalis and able sheath after 180° rotation, and the use of the reverse X-ray symptomatic AS underwent successful TAVI. Three-dimensional image are efficient in order to perform TAVI in a patient with reconstruction of a preoperative cardiac angio CT before TAVI dextrocardia situs inversus. These methods are theoretically use- was useful to confirm the relative positions of the heart and great ful for TAVI in the SAPIEN 3 era. vessels4. In addition, Good et al showed that, when a patient with dextrocardia situs inversus undergoes TAVI, it is important to rotate the NovaFlex+ Transfemoral System by 180° when insert- Conflict of interest statement ing it into the expandable sheath5. The authors have no conflicts of interest to declare. Understanding cardiac structure and appropriate modification of the procedure are mandatory in order to perform TAVI in patients References with dextrocardia, because the structure of heart and arteries is dif- 1. Smith CR, Leon MB, Mack MJ, Miller DC, Moses JW, ferent from normal. Two important issues for successful TAVI are: Svensson LG, Tuzcu EM, Webb JG, Fontana GP, Makkar RR, 1) insertion of the NovaFlex+ Delivery System into the expand- Williams M, Dewey T, Kapadia S, Babaliaros V, Thourani VH, able sheath after 180° rotation, and 2) the use of the reverse X-ray Corso P, Pichard AD, Bavaria JE, Herrmann HC, Akin JJ, image. The correct insertion and advancement of the NovaFlex+ Anderson WN, Wang D, Pocock SJ; PARTNER Trial Investigators. Delivery System into the expandable sheath is crucial, and this Transcatheter versus surgical aortic-valve replacement in high-risk involves aiming the Edwards logo downwards instead of upwards. patients. N Engl J Med. 2011;364:2187-98. This should result in a smooth delivery of the device into the aor- 2. Leon MB, Smith CR, Mack MJ, Miller DC, Moses JW, tic valve through the right-sided aortic arch. Furthermore, the Svensson LG, Tuzcu EM, Webb JG, Fontana GP, Makkar RR, reverse structure of the arch and ascending aorta can lead to dif- Brown DL, Block PC, Guyton RA, Pichard AD, Bavaria JE, ficulty in performing TAVI. Therefore, the reverse X-ray image is Herrmann HC, Douglas PS, Petersen JL, Akin JJ, Anderson WN, very effective and useful for understanding the orientation of the Wang D, Pocock S; PARTNER