JOURNAL OF VIROLOGY JOURNAL OF VIROLOGY

VOLUME 11 * NUMBER 2 * FEBRUARY 1973

EDITORIAL BOARD

Robert R. Wagner, Editor-in-Chief (1977) University of Virginia School of Medicine, Charlottesville

Myron Levine, Editor (1976) Norman P. Salzman, Editor (1975) School of Medicine, National Institute of Allergy and University of Michigan, Infectious Diseases, Ann Arbor Bethesda, Md.

Dwight L. Anderson (1974) Angus Graham (1975) Bernard Moss (1974) David Baltimore (1975) D. MacDonald Green (1974) Elmer R. Pfefferkorn (1974) Marcel A. Baluda (1975) Klaus Hummeler (1973) Lennart Philipson (1973) Allan M. Campbell (1975) Paul J. Kaesberg (1973) Fred Rapp (1975) Purnell Choppin (1974) Albert S. Kaplan (1973) Bernard Roizman (1973) Eugene H. Cota-Robles (1973) Edwin D. Kilbourne (1973) Aaron J. Shatkin (1973) Vittorio Defendi (1973) David W. Kingsbury (1973) Robert W. Simpson (1973) Walter Doerfler (1974) Lloyd M. Kozloff (1976) Donald F. Summers (1973) Richard M. Franklin (1973) Margaret Lieb (1973) Howard M. Temin (1973) Robert M. Friedman (1973) Jean Lindenmann (1973) Peter Vogt (1973) Harold S. Ginsberg (1973) Royce Z. Lockart, Jr. (1975) John S. Wiberg (1973) l Marc Girard (1974) Christopher K. Mathews (1973) Julius Youngner (1973)

Robert A. Day, Managing Editor, 1913 I St., N. W., Washington, D.C. 20006

EX OFFICIO

R. G. E. Murray, President (1972-1973) L. Leon Campbell, Vice-President (1972-1973) Donald E. Shay, Secretary T. J. Carski, Treasurer

The Journal of Virology, a publication of the American to the ASM Publications Office, 1913 I St., N.W., Wash- Society for Microbiology, 1913 I St., N.W., Washington, D.C. ington, D.C. 20006 (area 202 833-9416). Correspondence from 20006, is devoted to the dissemination of fundamental ASM members relating to membership dues, member knowledge concerning viruses of bacteria, plants, and ani- subscriptions, changes of address, incorrect address, mals. Investigators are invited to submit reports of original incorrect journals, etc., should be directed to the Executive research in all areas of basic virology, including biochemis- Secretary, American Society for Microbiology, 1913 I St., try, biophysics, genetics, immunology, morphology, and N.W., Washington, D.C. 20006. Published monthly by the physiology. The Journal is issued monthly, two volumes per ASM at 428 E. Preston St., Baltimore, Md. 21202. year. The subscription price is $40 (foreign, $41) per year; single copies are $4.00 (foreign, $4.25). Members of the American Society for Microbiology may receive the Journal Second-class postage paid at Baltimore, Md. 21202, and as part of their dues. Correspondence relating to sub- at additional mailing offices scriptions, reprints, defective copies, availability of back Made in the U.S.A. issues, lost or late proofs, disposition of submitted manu- Copyright 0 1973, American Society for Microbiology. scripts, and general editorial matters should be directed All Rights Reserved. JOURNAL OF VIROLOGY INSTRUCTIONS TO AUTHORS Correspondence. Submit manuscripts in dupli- be typed in alphabetical order, by first author, and cate (original and one carbon) to ASM Publica- numbered. Names of journals are abbreviated ac- tions office, 1913 I St., N.W., Washington, D.C. cording to Chemical Abstracts Service Source In- 20006. dex (American Chemical Society, 1970). Litera- General policy. Any manuscript submitted must ture citations should be restricted to closely be a report of unpublished original research, which pertinent papers. Citations of abstracts, theses, is not being considered for publication elsewhere. "unpublished data ""personal communication, " A manuscript accepted and published by the and "in press" will not be accepted in the Litera- Journal must not be published again in any form ture Cited, but may be used parenthetically in without the consent of ASM. the text. A charge of $25 per printed page is assessed for Tables. Each table should be typed on a sepa- publication in the Journal. Most institutions and rate page. The data should be arranged so that granting agencies in the United States permit the columns of like material read down, not across. payment of publication charges as part of their The headings should be sufficiently clear so that general research support. It is recognized, how- the meaning of the data will be understandable ever, that such funds are not always available to without reference to the text. Explanatory foot- laboratories outside the United States. In such notes are permitted, but detailed descriptions of cases, the cost of publication will be borne by the the experiments are not. The materials and meth- American Society for Microbiology. Ability or in- ods used to gain the data should properly remain ability to pay the publication charge is not a factor in the section of that name. in the selection of manuscripts for publication. Figures. A complete set of figures, preferably The "editorial style" of the Journal essentially glossy photographs, should accompany each of the follows the CBE Style Manual (3rd ed., AIBS, two copies of the manuscript. Each figure should 1972). "Instructions" published in the Journal be numbered and should include the name of the of Bacteriology apply also to the Journal of author, either in the margin or on the back Virology. Biochemical abbreviations and nomen- (marked lightly with a soft pencil). Graphs (sub- clature should essentially follow "Biochemical mit as photographs) should be finished drawings Nomenclature" in Handbook of Biochemistry not needing further artwork or type-setting. Ab- (2nd ed., 1970, H. A. Sober, ed., The Chemical solutely no part of a graph should be typewritten Rubber Co., Cleveland, p. A4-A24). Normally, (except the legend, which should be typed on a abbreviations (except those of standard units of separate page). All lettering should be done with measurement and symbols of the elements) should a lettering set. Most graphs will be reduced to one- be defined and introduced parenthetically at first column width, and all elements in the drawing use in the text. Genetic symbols should essentially should be prepared to withstand this reduction. follow the recommendations of Demerec et al. The legend of the figure should provide enough (Genetics 54:61, 1966). Enzyme activity should information so that the figure is understandable be expressed in terms of international units (En- without reference to the text. Experimental de- zyme Nomenclature, Elsevier Publishing Co., tails from Materials and Methods should not be 1965), and the EC number should be given paren- repeated in figure legends. thetically at first use in the text. In expressing Notes. The accepted form for Notes is somewhat lengths, weights, and volumes, the prefixes nano different from the foregoing. Contributors should (n) and pico (p) should be used instead of milli- consult a recent issue of the Journal for style. micro (miA) and micromicro (Juj). Express lengths Notes should not exceed 500 words. The Abstract in nanometers (nm; 10-9 m) or in micrometers should not exceed 25 words. CUm; 10-6 m) instead of millimicrons (m/a; 10-9 m), Nomenclature of viruses. Viruses named after a microns (M; 10-6 m), or Angstroms (A; 10-1im). disease should be written as separate words in Express parts per million (ppm) as micrograms lower-case roman, except when the name of the per milliliter (,ug/ml), micrograms per gram (jug/g), disease is derived from a proper noun: herpes or microliters per liter (.liters/liter), as appropri- simplex virus, measles virus, Newcastle disease ate. In general, measurements should be expressed virus, poliomyelitis virus, varicella-zoster virus, in terms of standard international metric units. vaccinia virus. The Journal reserves the privilege of editing man- Most other viruses should be written as a single uscripts to make them conform with the adopted word in lower case: adenovirus, coxsackievirus, style. cytomegalovirus, echovirus, herpesvirus, mengo- Form of manuscript. All parts of the manuscript virus, picornavirus, poliovirus, poxvirus. should be typed double-space or, preferably, Copyright. Once a paper has been published in triple-space. Most manuscripts can and should be the Journal, which is a' copyrighted publication, divided into the following sections: Abstract, In- the legal ownership of all parts of the paper, in- troduction, Materials and Methods, Results, Dis- cluding the illustrations, has passed from the cussion, Acknowledgments, and Literature Cited. author to the Journal. If the same author, or any Only one weight of heading (paragraph lead-in) author, wishes to republish material previously should be used within each section. published in the Journal, he must first receive Abstract. An Abstract appears at the beginning written permission from ASM. of each paper in the Journal. The abstract should Reprints. Reprints (in multiples of 100) will be not exceed 250 words. furnished contributors when ordered in advance. Literature Cited. In the text, references are cited A table showing the cost of reprints, and an order by number. The Literature Cited section should form, will be sent with the proof. YOU ARE INVITED to attend THE 73RD ANNUAL MEETING AMERICAN SOCIETY FOR MICROBIOLOGY Over 200 Scientific Sessions Symposia Special Lectures Seminars Round Tables Workshops Contributed Papers Over 250 Exhibits Technical-Scientific-Educational 6-11 May 1973 Miami Beach, Florida Registration Open to All Interested Persons

For Additional Information: The Executive Secretary, ASM, 1913 Eye St., NW, Washington, DC 20006