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Table of Contents (PDF) July 22, 2014 u vol. 111 u no. 29 u 10391–10780 Cover image: Pictured are islets of Langerhans, coated with biocompatible and permeable hydrogels. Alice A. Tomei et al. developed a method for encapsulating the islets with thin, complete, and uniform coatings of similar thickness on islets of different sizes. The authors found that encapsulation does not impair islet function and may allow for islet transplanta- tion without immunosuppression. See the article by Tomei et al. on pages 10514–10519. Image courtesy of Alice A. Tomei. From the Cover 10514 Encapsulation of islets of Langerhans 10580 Mitochondrial pore components 10604 Age and polio transmission 10620 Game theory and population genetics 10636 Passenger pigeon population fluctuation Contents COMMENTARIES 10396 Identifying the components of the elusive mitochondrial THIS WEEK IN PNAS permeability transition pore Jason Karch and Jeffery D. Molkentin See companion article on page 10580 10391 In This Issue 10398 Diverse forms of selection in evolution and computer science LETTERS (ONLINE ONLY) Nicholas H. Barton, Sebastian Novak, and Tiago Paixão See companion article on page 10620 E2915 Are viral small RNA regulating Dengue virus replication beyond serotype 2? 10400 Pleistocene range dynamics and episodic rarity in an Esteban Finol extinct bird A. Townsend Peterson E2917 Reply to Finol: Viral small RNA from Dengue virus and See companion article on page 10636 its regulatory role in different serotypes Mazhar Hussain and Sassan Asgari PNAS PLUS SCIENCE AND CULTURE—How science intersects with culture 10402 Significance Statements 10393 Science and Culture: Hunting fractals in the music of Brief statements written by the authors about the significance of J. S. Bach their papers. Stephen Ornes QNAS INAUGURAL ARTICLE 10394 QnAs with Thomas Jessell 10404 Structure of a new DNA-binding domain which regulates Prashant Nair pathogenesis in a wide variety of fungi Matthew B. Lohse, Oren S. Rosenberg, Jeffery S. Cox, Robert M. Stroud, Janet S. Finer-Moore, Free online through the PNAS open access option. and Alexander D. Johnson PNAS u July 22, 2014 u vol. 111 u no. 29 u iii–viii Downloaded by guest on September 24, 2021 COMPUTER SCIENCES PHYSICAL SCIENCES 10620 Algorithms, games, and evolution Erick Chastain, Adi Livnat, Christos Papadimitriou, APPLIED MATHEMATICS and Umesh Vazirani 10411 A simple generative model of collective online behavior See Commentary on page 10398 James P. Gleeson, Davide Cellai, Jukka-Pekka Onnela, Mason A. Porter, and Felix Reed-Tsochas EARTH, ATMOSPHERIC, AND PLANETARY SCIENCES 10604 The role of older children and adults in wild 10468 Spin crossover in ferropericlase and velocity poliovirus transmission heterogeneities in the lower mantle Isobel M. Blake, Rebecca Martin, Ajay Goel, Nino Zhongqing Wu and Renata M. Wentzcovitch Khetsuriani, Johannes Everts, Christopher Wolff, Steven Wassilak, R. Bruce Aylward, and Nicholas C. Grassly 10491 Stone tools from the ancient Tongan state reveal prehistoric interaction centers in the Central Pacific APPLIED PHYSICAL SCIENCES Geoffrey R. Clark, Christian Reepmeyer, Nivaleti 10416 SERS and MD simulation studies of a kinase inhibitor Melekiola, Jon Woodhead, William R. Dickinson, demonstrate the emergence of a potential drug and Helene Martinsson-Wallin discovery tool 10624 Flight performance of the largest volant bird Dhanasekaran Karthigeyan, Soumik Siddhanta, Annavarapu Daniel T. Ksepka Hari Kishore, Sathya S. R. R. Perumal, Hans Ågren, Surabhi Sudevan, Akshay V. Bhat, Karanam Balasubramanyam, Rangappa Kanchugarakoppal Subbegowda, Tapas K. ENGINEERING Kundu, and Chandrabhas Narayana 10514 Device design and materials optimization of conformal coating for islets of Langerhans 10422 Role of projection in the control of bird flocks Alice A. Tomei, Vita Manzoli, Christopher A. Fraker, Daniel J. G. Pearce, Adam M. Miller, George Rowlands, Jaime Giraldo, Diana Velluto, Mejdi Najjar, Antonello and Matthew S. Turner Pileggi, R. Damaris Molano, Camillo Ricordi, Cherie L. 10427 Collective spin 1 singlet phase in high-pressure oxygen Stabler, and Jeffrey A. Hubbell Yanier Crespo, Michele Fabrizio, Sandro Scandolo, 10773 Intratumor heterogeneity alters most effective and Erio Tosatti drugs in designed combinations 10433 The magnetoelectrochemical switch Boyang Zhao, Michael T. Hemann, Petru Lunca Popa, Neil T. Kemp, Hicham Majjad, Guillaume and Douglas A. Lauffenburger Dalmas, Vina Faramarzi, Christian Andreas, Riccardo Hertel, and Bernard Doudin ENVIRONMENTAL SCIENCES 10473 Unspeciated organic emissions from combustion sources CHEMISTRY and their influence on the secondary organic aerosol budget in the United States 10438 Unusual kinetics of thermal decay of dim-light Shantanu H. Jathar, Timothy D. Gordon, Christopher J. photoreceptors in vertebrate vision Hennigan, Havala O. T. Pye, George Pouliot, Peter J. Adams, Ying Guo, Sivakumar Sekharan, Jian Liu, Victor S. Batista, Neil M. Donahue, and Allen L. Robinson John C. Tully, and Elsa C. Y. Yan 10444 Detouring of cisplatin to access mitochondrial genome PHYSICS for overcoming resistance Sean Marrache, Rakesh K. Pathak, and Shanta Dhar 10479 4D multiple-cathode ultrafast electron microscopy John Spencer Baskin, Haihua Liu, and Ahmed H. Zewail 10450 Alteration of the lipid profile in lymphomas induced by MYC overexpression 10485 Giant vacuum forces via transmission lines Livia S. Eberlin, Meital Gabay, Alice C. Fan, Arvin M. Ephraim Shahmoon, Igor Mazets, and Gershon Kurizki Gouw, Robert J. Tibshirani, Dean W. Felsher, and Richard N. Zare 10456 Crystal structure and encapsulation dynamics of ice SOCIAL SCIENCES II-structured neon hydrate Xiaohui Yu, Jinlong Zhu, Shiyu Du, Hongwu Xu, Sven C. ANTHROPOLOGY Vogel, Jiantao Han, Timothy C. Germann, Jianzhong 10491 Stone tools from the ancient Tongan state Zhang, Changqing Jin, Joseph S. Francisco, reveal prehistoric interaction centers in the and Yusheng Zhao Central Pacific 10462 Testing for memory-free spectroscopic coordinates by Geoffrey R. Clark, Christian Reepmeyer, Nivaleti 3D IR exchange spectroscopy Melekiola, Jon Woodhead, William R. Dickinson, Joanna A. Borek, Fivos Perakis, and Peter Hamm and Helene Martinsson-Wallin 10744 Covalent agonists for studying G protein-coupled 10497 Environmental impact of geometric earthwork receptor activation construction in pre-Columbian Amazonia Dietmar Weichert, Andrew C. Kruse, Aashish Manglik, John Francis Carson, Bronwen S. Whitney, Francis E. Christine Hiller, Cheng Zhang, Harald Hübner, Brian K. Mayle, José Iriarte, Heiko Prümers, J. Daniel Soto, Kobilka, and Peter Gmeiner and Jennifer Watling iv u www.pnas.org Downloaded by guest on September 24, 2021 ECONOMIC SCIENCES 10532 Identification of a two-component fatty acid kinase 10503 Irrational exuberance and neural crash warning responsible for host fatty acid incorporation by signals during endogenous experimental Staphylococcus aureus market bubbles Joshua B. Parsons, Tyler C. Broussard, Jeffrey L. Bose, Alec Smith, Terry Lohrenz, Justin King, P. Read Montague, Jason W. Rosch, Pamela Jackson, Chitra Subramanian, and Colin F. Camerer and Charles O. Rock 10538 The Legionella effector SidC defines a unique family SOCIAL SCIENCES of ubiquitin ligases important for bacterial phagosomal remodeling 10411 A simple generative model of collective online behavior FoSheng Hsu, Xi Luo, Jiazhang Qiu, Yan-Bin Teng, James P. Gleeson, Davide Cellai, Jukka-Pekka Onnela, Jianping Jin, Marcus B. Smolka, Zhao-Qing Luo, Mason A. Porter, and Felix Reed-Tsochas and Yuxin Mao 10544 Allosteric regulation of γ-secretase activity by a phenylimidazole-type γ-secretase modulator BIOLOGICAL SCIENCES Koji Takeo, Shun Tanimura, Takehiro Shinoda, Satoko Osawa, Ivan Krasmirov Zahariev, Naoki Takegami, Yoshiko ANTHROPOLOGY Ishizuka-Katsura, Naoko Shinya, Shizuka Takagi-Niidome, 10509 Temporal labyrinths of eastern Eurasian Aya Tominaga, Noboru Ohsawa, Tomomi Kimura-Someya, Pleistocene humans Mikako Shirouzu, Satoshi Yokoshima, Shigeyuki Yokoyama, Xiu-Jie Wu, Isabelle Crevecoeur, Wu Liu, Song Xing, Tohru Fukuyama, Taisuke Tomita, and Takeshi Iwatsubo and Erik Trinkaus BIOPHYSICS AND COMPUTATIONAL BIOLOGY APPLIED BIOLOGICAL SCIENCES E2947 Catalytic strategy used by the myosin motor to hydrolyze ATP 10514 Device design and materials optimization of conformal Farooq Ahmad Kiani and Stefan Fischer coating for islets of Langerhans Alice A. Tomei, Vita Manzoli, Christopher A. Fraker, 10416 SERS and MD simulation studies of a kinase inhibitor Jaime Giraldo, Diana Velluto, Mejdi Najjar, Antonello demonstrate the emergence of a potential drug Pileggi, R. Damaris Molano, Camillo Ricordi, Cherie L. discovery tool Stabler, and Jeffrey A. Hubbell Dhanasekaran Karthigeyan, Soumik Siddhanta, Annavarapu Hari Kishore, Sathya S. R. R. Perumal, Hans Ågren, Surabhi BIOCHEMISTRY Sudevan, Akshay V. Bhat, Karanam Balasubramanyam, Rangappa Kanchugarakoppal Subbegowda, Tapas K. E2918 Phosphoproteomic analysis identifies the tumor Kundu, and Chandrabhas Narayana suppressor PDCD4 as a RSK substrate negatively regulated by 14-3-3 10438 Unusual kinetics of thermal decay of dim-light Jacob A. Galan, Kathryn M. Geraghty, Geneviève Lavoie, photoreceptors in vertebrate vision Evgeny Kanshin, Joseph Tcherkezian, Viviane Calabrese, Ying Guo, Sivakumar Sekharan, Jian Liu, Victor S. Batista, Grace R. Jeschke, Benjamin E. Turk, Bryan A. Ballif, John C. Tully, and Elsa C. Y. Yan John Blenis, Pierre Thibault, and Philippe P. Roux 10550 Energy landscape views for interplays among folding, E2928 DEAD-box
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