Product Datasheet
ATG4A Antibody
Catalog No: #32744
Orders: [email protected] Description Support: [email protected]
Product Name ATG4A Antibody
Host Species Rabbit
Clonality Polyclonal
Purification Antibodies were purified by affinity purification using immunogen.
Applications WB
Species Reactivity Human,Mouse
Specificity The antibody detects endogenous level of total ATG4A protein.
Immunogen Type Recombinant Protein
Immunogen Description Recombinant protein of human ATG4A.
Target Name ATG4A
Other Names APG4A; AUTL2;
Accession No. Swiss-Prot:Q8WYN0NCBI Gene ID:115201
SDS-PAGE MW 45KD
Concentration 1.0mg/ml
Formulation Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02%
sodium azide and 50% glycerol.
Storage Store at -20°C
Application Details
WB 1:500 - 1:2000
Images
Western blot analysis of extracts of various cell lines, using ATG4A at 1:1000 dilution.
Background
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54
Address: 8400 Baltimore Ave., Suite 302, College Park, MD 20740, USA http://www.sabbiotech.com 1 family of cysteine proteases. Transcript variants that encode distinct isoforms have been identified.
Note: This product is for in vitro research use only and is not intended for use in humans or animals.
Address: 8400 Baltimore Ave., Suite 302, College Park, MD 20740, USA http://www.sabbiotech.com 2