Posters A-Z

Adams, Sophie Investigating the role of amplification in exosome-mediated 47 remodelling of the pancreatic tumour microenvironment.

Adhami-Mojarad, Bahareh CEP19 Cooperates with FOP and CEP350 to drive early stages of 48 ciliogenesis program

Akhshi, Tara Hedgehog pathway can regulate ciliogenesis 49

Alieva, Irina Ultrastructural features of the endotheliocyte centrosome and its 50 possible involvement into the functional activity of endothelium

Alvarez Rodrigo, Ines Dissecting Polo kinase recruitment to the centrosome 51

Amargant, Farners Characterization of the human sperm centrosome and its role in fertility 52

Andersen, Jens S Identification of candidate phosphorylation sites regulating 53 biogenesis

Arbi, Marina Geminin family members take center stage in the network 54 controlling multiple cilia formation

Arnandis, Teresa Non- autonomous invasion mediated by centrosome amplification 55

Au, Kin Chung Franco GAS2L1 Is a Centriole-associated That Functions in 56 Centrosome Disjunction

Aydogan, Mustafa Kinetics of daughter centriole growth in flies: How does distal-end 57 contribute to setting the centriole size?

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B, Binshad SCF-FBXW7 E3 ligase regulates centriole duplication by targeting 58 HsSAS-6

Banterle, Niccolò Probing SAS-6 assembly dynamics with high speed Atomic Force 59 Microscopy

Basavaraju, Shivakumar CHK1- dependent mechanisms of centrosome amplification after DNA 60 damage

Beyer, Tina Cluap1: Isoform-specific protein complex analysis and 61 CRISPR/Cas9-mediated knock-out revealed new functions of Cluap1 in cellular dynamics.

Bianchi, Sarah Presenter: Vakonakis, John The C. elegans centriolar protein SAS-5 binds to facilitate 62 assembly

Bierkamp, Christiane The role of during cellular differentiation and mouse skin 63 morphogenesis

Bornens, Michel Presenter: Allier, Cedric The role of centrosome in cell division cycle as monitored by lens-free 64 microscopy

Bose, Arunabha Regulation of centrosome duplication by 14-3-3? 65

Breslow, David A comprehensive portrait of cilia and ciliopathies from a CRISPR-based 66 screen for Hedgehog signaling

Brouhard, Gary C. elegans microtubules are highly dynamic and have non-canonical 67 lattices

Page 16 Posters A-Z

Bui, Hien Age selective segregation of during division is 68 mediated by the mitotic spindle

Burkhalter, Martin D. Imbalanced mitochondrial function induces heterotaxy via aberrant 69 ciliogenesis

Camargo Ortega, German Akna, a new component of the interphase centrosome, regulates 70 neurogenesis by anchoring

Cernohorska, Marketa A cell-free assay for microtubule doublet assembly 71

Chan, Vincent Presenter: Chao-Chu, Jennifer To study the effect of NEK2 on instability in hepatocellular 72 carcinoma

Chinen, Takumi Divergent acentrosomal pathways ensure spindle bipolarity in human 73 cells

Cosenza, Marco R. Asymmetric centriole rosettes in bipolar spindles cause chromosome 74 missegregation in cancer

Curinha, Ana Functional Analysis of Rbm26 75

Cury, Nathália Transcriptionally, karyotypic and cell cycle consequences of microtubule 76 disassembly in acute lymphoblastic leukemia

Damen, Mareike Presenter: Bazzi, Hisham are required for the development of the skin epidermis and 77 hair follicles

Dammermann, Alexander Centrioles initiate cilia assembly but are dispensable for maturation and 78 maintenance in C. elegans

Page 17 EMBO Conference: Centrosomes and Spindle Pole Bodies

Delgehyr, Nathalie An apical actin network induced by the beating of motile ependymal 79 cilia protects basal bodies against the shear stress exerted by the cilia

Dobbelaere, Jeroen Identification and characterization of cilia in Drosophila 80 melanogaster

Duenas-Sanchez, Rafael Role of Bem2 in the integrity of the Spindle Position Checkpoint 81

Dwivedi, Devashish Hook2 is a dynein-dynactin adaptor required for cytokinesis 82

Erpf, Anna Christina A novel protein required for bipolar spindle formation in the one-cell 83 stage Caenorhabditis elegans embryo

Farrell, KC Moderating influence of centrosome on microtubule polymer and cell 84 mechanics

Firat-Karalar, Elif Nur The retinal degeneration gene product CCDC66 functions in 85 formation and is regulated by centriolar satellites

Fitzpatrick, Alexa Characterization of Retinitis Pigmentosa GTPase Regulator Mutations in 86 Patients with Syndromic Phenotypes: Linking Primary and Motile Ciliopathies

Florindo, Claudia Mob1: defining cell polarity for proper cell division 87

Ford, Jodie From spirals to rings: protein engineering of C. elegans SAS-6 88

Frikstad, Kari-Anne M. A CEP104-CSPP1 complex is required for formation of primary cilia 89 competent in Hedgehog-signaling

Page 18 Posters A-Z

Gambarotto, Davide Presenter: Gambarotto, Davide; Cernohorska, Marketa; Hamel, Virginie; Guichard, Paul Nanometric protein cartography of centrioles using Expansion 90 microscopy

Gartenmann, Lisa Revealing Centriole Secrets – Examining The Protein Interactions That 91 Form The Centriole In Vivo

Giessl, Andreas Pericentrin, identified at the basal-body complex in mammalian 92 photoreceptor cells, interacts with Nesprin protein Syne-2 in the retina

Gogendeau, Delphine Down-regulation of different transition zone proteins in Paramecium 93 induces antagonistic effects on cilia stability

Gomes, Beatriz Multivalent interactions of the scaffold protein SPD-5 underlie PCM 94 assembly in C. elegans

Gönczy, Pierre Presenter: Pierron, Marie Uncovering mechanisms of centriole elimination during C. elegans 95 oogenesis

Gopalakrishnan, Jay Presenter: Mariappan, Aruljothi ¬¬Premature activation of extra centrosomes by a CPAP-tubulin 96 inhibitor selectively prevents cancer cellular proliferation

Goranci-Buzhala, Gladiola Cilia induction to prevent proliferation of glioma stem cells in vitro 97

Goundiam, Oumou Analysis of centrosome alterations in Epithelial Ovarian (EOCs) 98 reveals new types of defects

Gunzelmann, Judith Cooperation of the receptor Spc72, the microtubule polymerase Stu2 99 and g-TuSC at microtubule minus ends

Page 19 EMBO Conference: Centrosomes and Spindle Pole Bodies

Gupta, Hindol Human SAS-6 regulates centriole duplication by interacting with 100 gamma-tubulin ring complex proteins

Häfner, Julia Function of Cdk5rap2 during enucleation of mammalian erythroblasts 101

Haren, Laurence Role of GCP4, 5 and 6 in gamma-TuRC assembly 102

Hatzopoulos, Georgios Development of monobodies for dissecting centriole assembly 103

Hoffmann, Ingrid Presenter: Meyer, Annalena Ccdc61 is a novel centriolar satellite component that regulates spindle 104 assembly and symmetry

Hoffmann, Ingrid The Cullin4-DDB1 E3 Ubiquitin Ligase Complex regulates 105 Plk4- dependent centriole duplication

Howard, Ryan Investigating the relationship between poly (ADP-ribose) polymerases 106 and centrosome clustering in cancer cells

Hsu, Wen-hsin Adducin-1 is essential for spindle pole integrity through its interaction 107 with TPX2

Ito, Daisuke The yeast centriole-less centrosome reveals an ancestral role for the 108 pericentriolar matrix in centriole biogenesis

Jao, Li-En Regulation of centrosome maturation by localized RNA 109

Joachimiak, Ewa Phosphorylation sites on gamma-tubulin are essential for the structure 110 and functions of basal bodies in Tetrahymena

Page 20 Posters A-Z

Julner, Alexander High-throughput approach to understanding 111 dynamics

Kamranvar, Siamak A. Lack of integrin is associated with centrosome abnormality and 112 subsequent genomic instability

Kapoor, Varun Automated microtubule tracking: A potpourri of biology, physics, 113 computer vision and machine learning

Kessler, Kristin The centrosomal protein NIMA-related serine/threonine kinase -Nek 114 1- at cilia of sensory cells

Khouj, Ebtissal Centrin2 calcium-binding capacity is required for cilium formation but 115 not for NER activity.

Kim, Jaeyoun Presenter: Rhee, Kunsoo Pericentrin regulation of centriole association and separation during M 116 phase

Kitagawa, Daiju Crucial functions of the cartwheel structure in human procentriole 117 formation

Koca Caydasi, Ayse Spindle Pole Bodies as signaling hubs for the Spindle Position 118 Checkpoint of budding yeast

Koo, Stephanie Chuay-Yeng A novel TAO kinase inhibitor delays mitosis and induces mitotic 119 catastrophe in breast cancer cells with supernumerary centrosomes

Kovarikova, Petra Presenter: Kovarikova, Petra; Bernatik, Ondrej Tau tubulin kinase 2 phosphorylations in cilia initiation 120

Page 21 EMBO Conference: Centrosomes and Spindle Pole Bodies

Kumar, Dhivya The dynamic hub of the cell: centriolar satellites control the organization 121 of the centrosome

Kurtulmus, Bahtiyar LRRC45 organises centriolar satellites for ciliogenesis 122

Laláková, Jana Exploring the role of centrosome inheritance in cell fate determination in 123 human stem-like cells

Le Borgne, Pierrick Functional study of novel human PCD candidate in Paramecium 124

Le Guennec, Maeva Native architecture of Paramecium tetraurelia centriole 125

Le Roux-Bourdieu, Morgan How does centrosome age impact the mitotic spindle? 126

Leong, Su Ling In vitro reconstitution of microtubule nucleation by the gamma-tubulin 127 small complex and the Mto1/2 complex reveals a novel function for Mzt1

Lerit, Dorothy Regulation of transposable element activity and microtubule 128 organization in Drosophila

Li, Qiuhong Beatrice Presenter: Li, Qiuhong Beatrice; Kantsadi, Anastassia Insights into the molecular mechanisms of centriolar cartwheel 129 assembly

Lin, Yu-Chih Clathrin recruits GTSE1 to mitotic spindles to promote microtubule 130 stability and chromosome alignment

Lince-Faria, Mariana Centrosome regulation in mouse skeletal cells 131

Page 22 Posters A-Z

Liu, Pengfei NME7 Functions in Ciliogenesis and Left-right Asymmetry Development 132

Liu, Zhen High-throughput, accurate and specific diagnosis of primary ciliary 133 dyskinesia by quantitative super-resolution fluorescence imaging

Loncarek, Jadranka Presenter: Vasquez-Limeta, Alejandra; Loncarek, Jadranka Underdeveloped cartwheel and no Plk1-mediated centriole reduplication 134 in the absence of procentriole microtubules

Lopes, Carla A.M. Timing and regulation of centrosome amplification in human 135 tumorigenesis

Machlus, Kellie Centrosome Destabilization Through the Ubiquitin- Pathway 136 Regulates Platelet Production

Magistrati, Elisa Myosin VI, centrosomes and cell-cycle regulation: a new connection to 137 explore

Mahjoub, Moe Centrosome Amplification Disrupts Ciliogenesis and Causes Cystic 138 Kidney Disease

Marthiens, Véronique Spindle morphology tailoring through time: Identifying the mechanisms 139 that predispose the mammalian brain to microcephaly

McLamarrah, Tiffany An ordered pattern of Ana2 phosphorylation by Plk4 is required for 140 centriole assembly

Micale, Lucia Dissecting TRIM8 functions in the mitotic spindle regulation 141

Page 23 EMBO Conference: Centrosomes and Spindle Pole Bodies

Mikulenkova, Erika Centrosome amplification is associated with overexpression of 142 deltaNp73 isoform in cancer cell lines of neurogenic origin

Monje-Casas, Fernando Evaluation of the consequences of inverting the pre-established SPB 143 inheritance pattern in budding yeast

Nabais, Catarina Kinetics of Centriole Biogenesis in Space and Time 144

Nag, Rishita Investigating the novel centrosomal defects observed in early 145 Drosophila embryos mutant for xpd, a mitotic gene known to regulate the mitotic kinase cdk7

Nakamura, Takanori The molecular mechanisms that maintain the numerical integrity of 146 centrosomes under stress

Nguyen, Quynh PH Comparative sub-diffraction map of basal foot in primary and motile cilia 147 reveals its modular architecture and a novel type of cilia in human airway multiciliated cells

Novak, Zsofia Systematic in vivo studies of centrosome function in cellular and 148 developmental regulation

Ochi, Takashi Structure studies of a conserved-centrosomal protein that forms 149 protofilaments

Ogungbenro, Yetunde Adesanya Presenter: Morrison, Ciaran Centrobin links primary ciliogenesis and homologous recombinational 150 repair in vertebrates

Ota, Midori Symmetry breaking and negative feedback systems dictate centriole 151 duplication

Page 24 Posters A-Z

Passemard, Sandrine ASPM, the protein defective in the most frequent form of primary 152 microcephaly, is needed for PCM integrity in human

Pearson, Chad Centrosome trafficking defects in Down syndrome disrupt normal ciliary 153 assembly and

Pimenta-Marques, Ana Mechanisms Regulating Centrosome Maintenance and Elimination 154

Porter, Andrew Tiam1 depletion induces aberrant centriole duplication 155

Qiu, Jian Investigating redox regulation of the centriolar cartwheel protein 156 HsSAS-6

Quarantotti, Valentina Deciphering the proteomic composition of pericentriolar satellites 157

R. Balestra, Fernando Screen for new regulators of centrosome position in human cells 158

Raff, Jordan A homeostatic clock sets daughter centriole size in Drosophila 159

Ramani, Anand Plk1 phosphorylates Sas-4 at the onset of mitosis to expand 160 peri-centriolar material of mitotic centrosomes

Renzová, Tereza Acentrosomal divisions prevent self-renewal and trigger p53-dependent 161 differentiation in human pluripotent stem cells

Rumpf-Kienzl, Cornelia Biochemical analysis of the salt-insoluble scaffold 162

Rüthnick, Diana New insights into spindle pole body duplication 163

Page 25 EMBO Conference: Centrosomes and Spindle Pole Bodies

Sabat-Pospiech, Dorota Targeting an Achilles’ heel of breast cancer: DUBs as novel targets for 164 KIFC1 dependent centrosome de-clustering

Saurya, Saroj Dynamics of centriole growth reveals key aspects of how centrioles 165 reach the actual size in Drosophila embryos

Seo, Mi Young Proteolytic cleavage of centrosomal proteins during apoptosis 166

Shak, Caroline Presenter: Shak, Caroline; Haworth, Alice Nesprin-1alpha recruits centrosomal proteins to the nuclear envelope to 167 form the microtubule organising centre in myogenesis

Shen, Yuehong Identification of Gamma-tubulin Ring Complex Regulators in Mammalian 168 Cells

Shin, Wonjung CEP215 is essential for glial process formation 169

Soares, Helena Presenter: Carmona, Bruno; Soares, Helena TBCCD1, a protein involved in centrosome nucleus connection, is an 170 interactor of the ciliopathy-related protein ofd1

Song, Mi Hye ATX-2, the C. elegans Ortholog of Human Ataxin-2, Regulates 171 Centrosome Size and Microtubule Dynamics

Steib, Emmanuelle POC16/WDR90 is a novel microtubule-binding protein important for 172 flagella and cilia formation

Su, Tiffany Identification and characterization of cilia proteins in Caenorhabditis 173 elegans

Page 26 Posters A-Z

Cancelled 174

Sydor, Andrew An Uncharacterized Protein Phosphatase 1 Regulatory Component is 175 Critical for Regulating Centriole Duplication and Forms a Novel Module with the Microcephaly Protein RTTN

Tanaka, Kayoko Molecular insights into microtubule anchoring matrix 176

Tassin, Anne-Marie Functional study of novel human PCD candidate genes in Paramecium 177

Tilwani, Sarika The role of 14-3-3e in regulating development of the epidermis 178

Cancelled 179

Tomaz, Lucian Mutated in Colorectal Cancer (Mcc): a novel centrosomal protein involved in adult intestinal homeostasis and disease 180

Tripathi, Shambhu Sharan Combinatorial Effect of Gamma Radiation & CXI-Benzo-84 on Microtubule Dynamics 181

Uddin, Borhan Human phosphatase CDC14A is localized to the and regulates ciliogenesis 182

Uzbekov, Rustem Discovery of a new morphological type of centrioles - centrioles without microtubules 183 van den Hoek, Hugo Presenter: van den Hoek, Hugo; Engel, Benjamin Cryo-Electron Tomography of Centriole and Rootlet Assembly in 184 Naegleria gruberi

Page 27 EMBO Conference: Centrosomes and Spindle Pole Bodies

Viol, Linda Regulation of the behavior of centrosomal proteins during mitosis 185

Vitre, Benjamin Contribution of the Intraflagellar Transport machinery to extra 186 centrosome clustering

Vlijm, Rifka Presenter: Vlijm, Rifka; Li, Xue Using Super-resolution microscopy to visualize the molecular 187 architecture of Centrosomes

Wainman, Alan Super-Resolution Microscopy on Centrioles and Centrosomes 188

Wang, Jennifer Centriole triplet microtubules are required for stable centriole formation 189 and inheritance in human cells

Wilhelm, Therese Replication stress causes Centriole Splitting and Chromosome Lagging 190 in Mitosis

Wise, John Pierce Centrosomes in Chemical Carcinogenesis: Chromosomal Instability, 191 Centrosome Amplification, and Premature Centriole Disengagement Are Key Steps in the Carcinogenic Mechanism of Hexavalent Chromium

Wu, Qianzhu Wu TRIM36 is a novel regulator of centriole duplication and mitotic spindle 192 assembly.

Xiao, Cally Presenter: Xiao, Cally; Bazzi, Hisham Stem cell potency determines the response to centrosome loss 193

Yang, T. Tony Presenter: Li, Li-Tzu Architecture of mammalian centriole distal appendages supports a 194 matrix that gates the primary cilium

Zhang, Wanlu Brr6 and Brl1 drive membrane fusion during nuclear pore complex 195 biogenesis in Saccharomyces cerevisiae

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