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Repertorium 2019

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Repertorium 2019 Inleiding 1. Cardiovasculair stelsel GECOMMENTARIEERD 2. Bloed en stolling GENEESMIDDELEN- 3. Gastro-intestinaal stelsel REPERTORIUM 4. Ademhalingsstelsel 2019 5. Hormonaal stelsel 6. Gynaeco-obstetrie 7. Urogenitaal stelsel 8. Pijn en koorts 9. Osteo-articulaire aandoeningen 10. Zenuwstelsel GENEESMIDDELENREPERTORIUM 2019 11. Infecties 12. Immuniteit 13. Antitumorale middelen 14. Mineralen, vitaminen en tonica 15. Dermatologie 16. Oftalmologie BCFI 17. Neus-Keel-Oren BELGISCH CENTRUM VOOR 18. Anesthesie FARMACOTHERAPEUTISCHE INFORMATIE Regelmatige updates op www.bcfi.be 19. Diagnostica Op www.bcfi.be: het Repertorium met regelmatige updates en prijsvergelijkingstabellen 20. Diverse geneesmiddelen Index Afkortingen Symbolen ademgest. = ademgestuurd i.tumor. = intratumoraal Voorschrift (zie ook Inl.3.) alc. = alcoholisch i.uter. = intra-uterien amp. = ampul i.v. = intraveneus R/ Medisch voorschrift vereist anti-Xa = anti-factor Xa i.ventr. = intraventriculair (R/) Medisch voorschrift of “op schriftelijke aanvraag van de auric. = auriculair i.vesic. = intravesicaal patiënt” bew. = bewaarmiddel i.vitr. = intravitreaal bruisgran. = bruisgranulaat KIE = kallidinogenase-inactivatoreenheid Terugbetaling (zie ook Inl.4.2.) bruispdr. = bruispoeder laryngofar. = laryngofaryngeaal a, b, c, cs, cx bruistabl. = bruistablet lok. = lokaal : voor meer uitleg over deze bucc. = buccaal m. = maand terugbetalingscategorieën, zie Inl.4.2. caps. = capsule maagsapresist. = maagsapresistent CFU = kolonie vormende eenheden max. = maximum Terugbetaling in hoofdstuk IV, d.w.z. in de meeste conc. = concentraat medic. = medicinaal gevallen na akkoord van de adviserend geneesheer van de cut. = cutaan mEq = milli-equivalent verzekeringsinstelling (a priori controle) deelb. = deelbaar (M)(I)E = (miljoen) (internationale) eenheid Terugbetaling in hoofdstuk II, d.w.z. zonder voorafgaand dent. = dentaal nas. = nasaal akkoord van de adviserend geneesheer van de disp. = dispergeerbaar ocul. = oculair verzekeringsinstelling, maar met a posteriori controle dos. = dosis omh. = omhuld J Speciale tegemoetkoming van het RIZIV voor de dr. = druppel opl(oss). = oplossing anticonceptiva voor vrouwen jonger dan 21 jaar drinkb. = drinkbaar oplosb. = oplosbaar druppelfl. = druppelfles or. = oraal h Terugbetaling slechts in kliniekverband emuls. = emulsie orodisp. = orodispergeerbaar endocerv. = endocervicaal orofar. = orofaryngeaal Chr speciale tegemoetkoming van het RIZIV bij bepaalde endotrach. = endotracheaal oromuc. = oromucosaal patiënten met chronische pijn epidur. = epiduraal p.artic. = peri-articulair epilaes. = epilaesionaal patr. = patroon Generiek, kopie, of originele specialiteit voldoende gedaald eq. = equivalent p.d. = per dag in prijs; geen supplement bij het remgeld en in categorie filmomh. = filmomhuld pdr. = poeder ‘goedkoop’ (groen symbool op de website) flac. = flacon p.neur. = perineuraal Originele specialiteit met supplement bij het remgeld, dus gastr. = gastrisch p.odont. = peri-odontaal niet in categorie ‘goedkoop’ (oranje symbool op de website) gastro-ent. = gastro-enteraal ppm = deeltjes per miljoen Originele specialiteit zonder supplement bij het remgeld, geïmpr. = geïmpregneerd rect. = rectaal maar niet in categorie ‘goedkoop’ (blauw symbool op de geregul. = gereguleerd s.c. = subcutaan website) gingiv. = gingivaal s.conj. = subconjunctivaal glob. = globule SKP = Samenvatting van de Kenmerken van Geneesmiddelenbewaking (zie ook Inl.6.2.1.) gran. = granulaat het Product H.G. = hospitaalgebruik s.mucos. = submucosaal Geneesmiddel waarvoor bijzondere aandacht wordt gevraagd i.arter. = intra-arterieel solv. = solvent i.v.m. ongewenste effecten i.artic. = intra-articulair SQ-T = gestandaardiseerde kwaliteitseenheid s Geneesmiddel waarvoor bijkomende “risicobeperkende i.burs. = intra-bursaal tablet activiteiten” vereist zijn (oranje driehoek op de website) i.camer. = intracameraal subling. = sublinguaal i.card. = intracardiaal susp. = suspensie Doping (zie ook Inl.3.) i.cavern. = intracaverneus tabl. = tablet i.cistern. = intracisternaal TE = tuberculine eenheid Product vallend onder de WADA-lijst van verboden i.derm. = intradermaal transderm. = transdermaal substanties in de sport i.laes. = intralaesionaal urethr. = urethraal Product dat niet verboden is, maar een positieve i.m. = intramusculair vag. = vaginaal dopingcontrole kan geven inf. = infusie verl. = verlengde infiltr. = infiltratie vloeist. = vloeistof Nierinsufficiëntie (zie ook Inl.6.1.2.) inhal. = inhalatie voorgev. = voorgevulde dosisreductie of contra-indicatie bij ernstige inj. = injectie vrijst. = vrijstelling instill. = instillatie nierinsufficiëntie i.ocul. = intra-oculair dosisreductie of contra-indicatie reeds bij matige i.oss. = intra-ossaal nierinsufficiëntie i.perit. = intraperitoneaal i.pleur. = intrapleuraal IR = reactiviteitsindex i.thec. = intrathecaal GECOMMENTARIEERD GENEESMIDDELEN- REPERTORIUM 2019 BCFI BELGISCH CENTRUM VOOR FARMACOTHERAPEUTISCHE INFORMATIE Regelmatige updates op www.bcfi.be II 32ste editie GECOMMENTARIEERD GENEESMIDDELENREPERTORIUM 2019 Belgisch Centrum voor Farmacotherapeutische Informatie (Centre Belge d’Information Pharmacothérapeutique) vzw, erkend door het Federaal Agentschap voor Geneesmiddelen en Gezondheids- producten (FAGG) Website: www.bcfi.be of www.cbip.be Correspondentie-adressen Redactie (betreffende de inhoud van de publicaties van het BCFI) BCFI p.a. Campus Heymans, Blok B, 1ste verdieping Corneel Heymanslaan 10 9000 Gent e-mail: [email protected] Administratief en technisch BCFI p.a. Federaal Agentschap voor Genees- middelen en Gezondheidsproducten (FAGG) Eurostation, blok II, 8ste verdieping Victor Hortaplein 40, bus 40 1060 Brussel e-mailadressen: [email protected] (betreffende de Redactieraad specialiteiten in het Gecommentarieerd T. Christiaens (Universiteit Gent), G. De Loof Geneesmiddelenrepertorium) (Domus Medica) en J.M. Maloteaux (Université [email protected] (betreffende wijzi- Catholique de Louvain), hoofdredacteurs gingen van e-mailadressen, aanvragen M.H. Antoine (Université Libre de Bruxelles), voor Repertorium; voor artsen, apothekers A. Baitar, G. Beuken (Société Scientifique de en tandartsen worden postadreswijziging Médecine Générale), M. Bogaert (Universiteit automatisch doorgegeven via de Kruis- Gent), D. Boudry, W. Buylaert (Universiteit Gent), puntbank van de Sociale Zekerheid); voor A. Crepel, M. De Maesschalck, P. De Paepe studenten gebeurt de verdeling via de (Universiteit Gent), C. Devillers, B. D’Hooghe, verantwoordelijke afdeling van hun faculteit N. Fierens, G. Goesaert, H. Habraken, L. Ham- of school (er worden geen afzonderlijke tiaux, G. Laekeman (Katholieke Universiteit exemplaren naar studenten opgestuurd) Leuven), I. Latour, H. Marsily, N. Mortier, T. Roisin (Belgisch Centrum voor Geneesmiddelenbewa- [email protected] (betreffende tech- king), J. Vandenhoven, A. Van Ermen, L. Vansnick nische aspecten rond de website en de (Algemene Pharmaceutische Bond), C. Veys elektronische versies van het Reper- torium) D/2019/0435/1 Verantwoordelijke uitgever: © De informatie die verschijnt in het Gecommentarieerd Thierry Christiaens Geneesmiddelenrepertorium mag niet overgenomen worden of verspreid worden zonder bronvermelding, en mag in Nekkersberglaan 31 geen geval gebruikt worden voor commercie¨ le of publici- 9000 Gent taire doeleinden. III Inhoudstafel Inleiding .................................................1 Inl. 1. Totstandkoming van het Repertorium ...........................1 Inl. 2. Handleiding bij het Repertorium ..............................3 Inl. 3. Specialiteiten, symbolen en afkortingen .........................5 Inl. 4. Prijzen en terugbetalingsmodaliteiten ...........................8 Inl. 5. Het Repertorium online en de BCFI-website www.bcfi.be .............11 Inl. 6. Goed gebruik van geneesmiddelen ...........................12 Inl. 7. Geneesmiddelenintoxicaties en medische urgenties ................30 1. Cardiovasculair stelsel ...................................33 1.1. Hypertensie .........................................33 1.2. Angina pectoris .......................................48 1.3. Hartfalen ...........................................52 1.4. Diuretica ...........................................56 1.5. Bèta-blokkers ........................................62 1.6. Calciumantagonisten ...................................68 1.7. Middelen inwerkend op het renine-angiotensinesysteem ............72 1.8. Antiaritmica .........................................80 1.9. Hypotensie .........................................87 1.10. Arteriële vaatstoornissen .................................89 1.11. Veno- en capillarotropica .................................91 1.12. Hypolipemiërende middelen ...............................93 1.13. Middelen bij pulmonale hypertensie .........................103 1.14. Alprostadil .........................................105 1.15. Middelen i.v.m. het sluiten van de ductus arteriosus ..............106 1.16. Associaties voor cardiovasculaire preventie ....................107 2. Bloed en stolling .......................................109 2.1. Antitrombotica ......................................109 2.2. Antihemorragica .....................................127 2.3. Middelen i.v.m. de bloedvorming ...........................131 3. Gastro-intestinaal stelsel .................................135 3.1. Maag- en duodenumpathologie ...........................135 3.2. Spasmolytica .......................................145 3.3. Lever-, galblaas- en pancreaspathologie
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