GTF2IRD1 Antibody Cat. No.: 29-032
GTF2IRD1 Antibody
Antibody used in WB on Transfected 293T at 2.5 ug/ml.
Specifications
HOST SPECIES: Rabbit
SPECIES REACTIVITY: Dog, Human
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region IMMUNOGEN: of human GTF2IRD1.
TESTED APPLICATIONS: ELISA, IHC, WB
GTF2IRD1 antibody can be used for detection of GTF2IRD1 by ELISA at 1:312500. APPLICATIONS: GTF2IRD1 antibody can be used for detection of GTF2IRD1 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
POSITIVE CONTROL: 1) Tranfected 293T Cell Lysate
PREDICTED MOLECULAR 106 kDa, 105 kDa WEIGHT:
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PURIFICATION: Antibody is purified by protein A chromatography method.
CLONALITY: Polyclonal
CONJUGATE: Unconjugated
PHYSICAL STATE: Liquid
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% BUFFER: sucrose.
CONCENTRATION: batch dependent
For short periods of storage (days) store at 4˚C. For longer periods of storage, store STORAGE CONDITIONS: GTF2IRD1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Additional Info
OFFICIAL SYMBOL: GTF2IRD1
GTF2IRD1, CREAM1, GTF3, MUSTRD1, RBAP2, WBSCR11, WBSCR12, hMusTRD1alpha1, ALTERNATE NAMES: BEN, WBS
ACCESSION NO.: NP_057412
PROTEIN GI NO.: 7705387
GENE ID: 9569
USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background and References
GTF2IRD1 contains five GTF2I-like repeats and each repeat possesses a potential helix- loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. GTF2IRD1 is related to Williams-Beuren syndrome, a multisystem developmental disorder. Western blots using three different antibodies against three unique regions of this protein target confirm the same apparent molecular BACKGROUND: weight in our tests. The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing of this gene generates at least 2 transcript variants.
REFERENCES: 1) Tassabehji, M., (2005) Science 310 (5751), 1184-1187.
ANTIBODIES FOR RESEARCH USE ONLY.
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