Experimental Pharmacology and Therapeutic Innovation in the Eighteenth Century
-e: EXPERIMENTAL PHARMACOLOGY AND THERAPEUTIC INNOVATION IN THE EIGHTEENTH CENTURY by ANDREAS-HOLGER MAEHLE A thesis submitted for the degree of Doctor of Philosophy of the University of London University College London 1996 ProQuest Number: 10017185 All rights reserved INFORMATION TO ALL USERS The quality of this reproduction is dependent upon the quality of the copy submitted. In the unlikely event that the author did not send a complete manuscript and there are missing pages, these will be noted. Also, if material had to be removed, a note will indicate the deletion. uest. ProQuest 10017185 Published by ProQuest LLC(2016). Copyright of the Dissertation is held by the Author. All rights reserved. This work is protected against unauthorized copying under Title 17, United States Code. Microform Edition © ProQuest LLC. ProQuest LLC 789 East Eisenhower Parkway P.O. Box 1346 Ann Arbor, Ml 48106-1346 ABSTRACT In the historiography of pharmacology and therapeutics, the 18th century is regarded as a period of transition from traditional, Galenistic materia medica to the beginnings of modern, experimental drug research. Ackerknecht (1973) characterized the pharmacotherapy of this period as a "chaotic mixture of chemiatric and Galenistic practices", yet acknowledged an "increasing tendency toward empiricism, partly even true experimentalism". This thesis explores this transitional phase for the first time in depth, examining the relations between pharmacological experimentation, theory-building, and therapeutic practice. Furthermore, ethical aspects are highlighted. The general introduction discusses the secondary literature and presents the results of a systematic study of pharmacological articles in relevant 18th-century periodicals. The identified main areas of contemporary interest, the spectrum of methods applied, and the composition of the authorship are described and interpreted.
[Show full text]