Information Management System Core Facility Laboratory ofestablishment the further strengthening itsservices with the center now moves towards the future by Through itscontinued innovation, the “Omics-based” research in the country. Center continues to provide excellence in Established in2009, the PhilippineGenome TOWARDS THE FUTURE , GENOME CENTER: Biobank andBiorepository , and THE PHILIPPINE PHILIPPINE THE Integrated Laboratory Clinical . Contact Us A. Ma.Regidor Street, UP Diliman,Quezon City 1101, Mondays to Fridays, 8.00 AM to 5.00 PM Office Hours: Website: Email: Phone: QUEZON HALL QUEZON pgc.up.edu.ph [email protected] +632 9818500ext. 8742

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FUTURE SERVICES www.pgc.up.edu.ph PHILIPPINE GENOME CENTER BIOBANK AND BIOREPOSITORY LABORATORY INFORMATION CLINICAL GENOMICS LABORATORY CORE FACILITY MANAGEMENT SYSTEM

World-class molecular The soon-to-be established Biobank and Biorepository Clinical Core Facility (BBCF) of the PGC, is envisioned to aid various Genomics diagnostic services for Filipino Laboratory research institutions by providing a systematic and regulated PHILIPPINE GENOME CENTER clinicians and families. storage of human tissues, animal and plant samples, and their associated data. A laboratory information management The Clinical Genomics Laboratory of the PGC is an up-coming system (LIMS) will also subsequently be offered as a biobank facility that will leverage the center’s expertise in service that will ensure efficient traceability, security, and technology to provide molecular diagnostic services for integrity of biospecimen-associated data. The BBCF is clinicians and their patients. The service will begin with tumor expected to house -80°C, -40°C, and liquid nitrogen freezers profiling services for cancer patients and eventually expand to accommodate various types of biospecimens for future to include molecular services for cardiology, diabetes and genomic studies. The building for the BBCF and LIMS is metabolism, among others. currently being constructed in UP Diliman. APPLICATIONS PLANNED WORKFLOW LIMS

BIOSPECIMEN COLLECTION Collection of biospecimens will handled by “omics” researchers and/or PGC’s research programs. Collection must be CANCER CARDIOLOGY DIABETES PHARMACO- MENTAL Tumor profiling Drug selection AND GENOMICS HEALTH accompanied by proper documentation Prognostication Risk assessment METABOLISM Drug interaction Drug selection and abide by set regulations. De- Screening Drug selection Patient-drug Phenotype identified data must be stored in LIMS*. Metabolic selection assessment screening Optimal dosing

PLANNED WORKFLOW L BIOSPECIMEN PROCESSING PGC’s DNA Sequencing (DSCF), Core Facility for (CFB) and The Laboratory Information Management System PLAN SUBMIT PROCESS REPORT INTERPRET Protein, Proteomics, and Metabolomics (LIMS) offers remote data access and management to Core Facility (PPMCF) will process facilitate information transfer between the Philippine I specimens. All resulting data will be incorporated to the LIMS*. Genome Center (PGC) and other researchers. It aims to ease the access of data through properly documented sample history, project status reports, M STORAGE AND MANAGEMENT protocols, analysis results, and other information Multi-disciplinary Submission of Processing of Report Result team meeting patient samples samples through generation interpretation Biospecimens with its associated data necessary for laboratory management. By providing with clinicians to PGC-CGL DSCF/CFB/ and counseling will be stored in PGC’s Biobank and and patients for PPMCF services Biorepository Core Facility (BBCF) an infrastructure for managing data workflows, LIMS molecular testing following optimal storage conditions for enables the integration of a standard set of policies S each sample type to preserve integrity. Samples will be de-identified and a code that ensures the integrity, security, and traceability of FACILITIES will be used to ensure data security. data.

• DNA SEQUENCING CORE FACILITY (DCSF) The LIMS aims to provide an interoperable system for safe and secure data transport, management, • CORE FACILITY FOR BIOINFORMATICS (CFB) RETRIEVAL AND DISTRIBUTION and storage. It will subsequently be offered as a • PROTEIN PROTEOMICS METABOLOMICS CORE FACILITY If allowed by the sample provider, biobank service to the raw and processed data from (PPMCF) biospecimen and data distribution may be done by the biobank to other qualified researchers and other research institutions affiliated • Planned integration with clinical genomic counseling research projects. with PGC. Through the LIMS, PGC envisions a well- services integrated system that will aid the research and

• Planned launch by Early 2020 *The PGC BCF Laboratory Information Management System (LIMS) will link all de- development of the scientific community. identified data and test results to specimens that will be stored and may be easily • Initial services to include molecular cancer diagnostics retrieved when needed.