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DED UN 18 O 98 F http://www.nesacs.org N Y O T R E I T H C E N O A E S S S L T A E A C R C I N S M S E E H C C TI N O CA January 2009 Vol. LXXXVII, No. 5 N • AMERI Monthly Meeting ACS President-Elect Joseph S. Francisco to Speak at the Brookline Holiday Inn 2009 Chair’s Statement By E. Joseph Billo Summer Scholar Report Chemical Weathering Along the Greenland Ice Sheet Margin By Sam Beal, Wheaton College Weinberg Lecture Report Biotech Leader Calls for More Aggressive Fact-gathering in Clinical Research By Robert Levy 9OU´LL ½ND THE WHOLE LABORATORY SCIENCE COMMUNITY HERE !#3$!# #O 0ROGRAMMING AT 0ITTCON ).6)4%$ 39-0/3)! /2'!.):%$ #/.42)"54%$ 3%33)/.3 "IOLOGICAL !PPLICATIONS OF #APILLARY 6ALIDATION OF "IOANALYTICAL %LECTROPHORESIS -ETHODS !DDRESSING MATRIX %VOLUTION OF -ODERN #HROMATOGRAPHY EFFECTS ION SUPPRESSION AND )32 #ELEBRATION OF YEARS OF THE 3UBDIVISION INCURRED SAMPLE REANALYSIS ON #HROMATOGRAPHY AND 3EPARATION .EW #ONCEPTS AND )NSTRUMENTS #HEMISTRY FOR %LECTROCHEMICAL 3ENSORS 4HE&UTUREOF(0,# -ETHOD$EVELOPMENT -ULTI RESIDUE 0ESTICIDE !NALYSIS 1UALITY BY $ESIGN°%VALUATING THE FOR &OOD 4ESTING #ONTROL 3PACE OF 2OBUST (0,# -ETHODS 5NDERSTANDING #HROMATOGRAPHY .EW $IMENSIONS IN -ULTIDIMENSIONAL WITH 3UB M 0ARTICLES 3EPARATIONS 1UALITY !SSURANCE OF -EASUREMENTS 9OUNG )NVESTIGATOR !WARD FROM AND 0RO½CIENCY 4ESTING 3UBDIVISION ON #HROMATOGRAPHY AND 3EPARATION #HEMISTRY 0RESSURIZED &LUIDS IN 3EPARATIONS 6ISIT WWWPITTCONORG FOR THE 4ECHNOLOGY COMPLETE TECHNICAL PROGRAM 7ELCOME TO 0ITTCON°YOUR ONCE A YEAR OPPORTUNITY TO GET TOGETHER WITH JUST ABOUT EVERYONE IN THE LABORATORY SCIENCE COMMUNITY 4HERE´S NO BETTER PLACE TO NETWORK WITH COLLEAGUES FROM ALL OVER THE WORLD OR TO MEET ONE ON ONE WITH EXPERTS IN EVERY DISCIPLINE -C#/2-)#+ 0,!#% #()#!'/ -!2#( ¯ !LL RIGHTS RESERVED 2 The Nucleus January 2009 The Northeastern Section of the American Chemical Society, Inc. Contents Office: Marilou Cashman, 23 Cottage St., Natick, MA 01360. 1-800-872-2054 Notable New England Chemists 4 (Voice or FAX) or 508-653-6329. ___________________________ e-mail: mcash0953(at)aol.com Part 3: from Myron S. Simon Any Section business may be conducted 2009 Chair’s Statement 4 via the business office above. NESACS Homepage: _________________________________ http://www.NESACS.org By E. Joseph Billo David Cunningham, Webmaster Monthly Meeting 5 ACS Hotline, Washington, D.C.: _______________________________________ 1-800-227-5558 Joseph S. Francisco, ACS President-Elect to Speak, “Everything Flows, Officers 2009 Nothing Stands Still:” A Future for the Chemical Sciences Chair: Announcements 6,11 Dr. E. Joseph Billo _____________________________________ 13 Shattuck Street NSYCC Brewing Competition, Aula Laudis request for nominations, Natick, MA 01760 508-653-3074, joseph.billo(at)verizon.net Grants-in-Aid Chair-Elect: Reports 6,14 John McKew ___________________________________________ Wyeth Research Connections to Chemistry, Northeast Regional Undergraduate Day 200 Cambridge Park Drive James Flack Norris Award Introductory Remarks 7 Cambridge, MA 02140 _____________ Immediate Past Chair: By Morton Z. Hoffman Marietta Schwartz Summer Scholar Report 8 Chemistry Department, UMass-Boston Boston, MA 02125 _________________________________ 617-287-6146; marietta.schwartz(at)umb.edu Chemical Weathering along the Greenland Ice Sheet Margin Secretary: By Sam Beal, Wheaton College, Norton, MA Michael Singer 12th Annual Weinberg Memorial Lecture Report 10 Sigma-Aldrich ____________ 3 Strathmore Rd., Natick, MA 01360 By Robert Levy 508-651-8151X291; msinger(at)sial.com Request for Nominations by NEIC 12 Treasurer: ________________________ James Piper 19 Mill Rd., Harvard, MA 01451 For 2009 Secondary School Chemistry Teacher Award 978-456-3155, piper28(at)attglobal.net January Historical Events in Chemistry 13 Auditor: ____________________ Anthony Rosner By Leopold May Archivist: NESACS Committee Chairs for 2009 15 Myron S. Simon ______________________ 20 Somerset Rd. Photos from the 2009 Norris Award Meeting 16 Newton, MA 02465; 617-332-5273 _______________ Romysimon(at)mindspring.com Cover: Trustees: NESACS 2009 Chair, Dr. E. Joseph Billo (Photo by Gary Gilbert) Joseph A. Lima, Esther A. H. Hopkins, Deadlines: Michael E. Strem March 2009 Issue: January 12, 2009 Councilors Alternate Councilors April 2009 Issue: February 13, 2009 Term Ends 12/31/2009 Catherine Costello Julia H.Miwa Patricia Mabrouk Alfred Viola Michaeline F. Chen Jerry P. Jasinski Dorothy J. Phillips Eva B. Binnun Amy Tapper Barney Grubbs The Nucleus is published monthly, except June and August by the Northeastern Section of the American Term Ends 12/31/2010 Chemical Society, Inc. Forms close for advertising on the 1st of the month of the preceding issue. Text Thomas R. Gilbert Timothy B. Frigo must be received by the editor six weeks before the date of issue. Pamela Nagafuji Mark Froimowitz Robert Lichter David Cunningham Editor: Michael P. Filosa, Ph.D., ZINK Imaging, Inc., 16 Crosby Drive, Building 4G, Michael Singer Erik Rozners Bedford, MA 01730 Email: Michael.filosa(at)zink.com; Tel: 508-843-9070 Term Ends 12/31/2011 Associate Editors: Myron S. Simon, 20 Somerset Rd., W. Newton, MA 02465, Tel: 617-332-5273 Doris I. Lewis C. Jaworek-Lopes Sheila E Rodman, Konarka Techologies Inc., 116 John St. Suite 12, Lowell, MA Mary Burgess Patrick M. Gordon 01852 email:srodman(at)konarka.com tel 978-569-1414 Morton Z. Hoffman Lawrence Scott Board of Publications: David Cunningham (Chair), Mary Mahaney, Vivian K. Walworth Michael P. Filosa Donald Rickter Kathi Brown Liming Shao Business Manager: Karen Piper, 19 Mill Rd., Harvard, MA 01451, Tel: 978-456-8622 Advertising Manager: Vincent J. Gale, P.O. Box 1150, Marshfield, MA 02050, All Chairs of standing Tel: 781-837-0424 Committees, the editor Contributing Editors: Morton Hoffman, Feature Editor; Dennis Sardella, Book Reviews of THE NUCLEUS, and Calendar Coordinator: Sheila Rodman, email: srodman(at)konarka.com the Trustees of Section Photographers: Morton Z. Hoffman and James Phillips Funds are members of the Board of Directors. Any Proofreaders: Donald O. Rickter, Myron S. Simon, Vivian K. Walworth, E. Joseph Billo, Councilor of the American Chemical Society Stefan G. Koenig residing within the section area is an ex officio Webmaster: David Cunningham, webmaster(at)nesacs.org member of the Board of Directors. Copyright 2008, Northeastern Section of the American Chemical Society, Inc. The Nucleus January 2009 3 Notable New 2009 Corporate Patrons ($2000+) Abbott Bioresearch Genzyme England Chair’s Lyophilization Service of New England Merck National ACS Chemists Statement Novartis By Myron S. Simon Pfizer By Joe Billo Schering Corporation Parker Cleaveland Greetings to all former, current, and Sepracor 1780-1858 future NESACS members! And there Serono Reproductive Institute are a lot of you – well over 6000 Vertex Pharmaceuticals Parker Cleaveland was born in Row- Wyeth Pharmaceuticals ley, Mass. He entered Harvard College chemists at last count. The section in 1795, had Aaron Dexter as his membership covers all walks of life, Patrons ($1000-$1999) teacher in chemistry, and graduated in from industry to academia and every- Aptuit 1799. In 1805 he was appointed Pro- thing in between, as well as people at Astra-Zeneca R&D Boston fessor of Mathematics and Natural Phi- all career stages, from college students Broad Institute losophy at Bowdoin College, began to to retired chemists. I am looking for- Creagen Biosciences ward to my year as Section Chair, and teach when he was scarcely twenty- Estate of Wallace Gleekman hope that you all will continue to par- five years old, and continued without Irix Pharmaceuticals ticipate fully in the variety of NESACS intermission until his death. Cleaveland Millennium Pharmaceuticals activities that will be taking place over PCI Synthesis began voluntary lectures in chemistry the next twelve months. During my Shasun USA and mineralogy in 1808 and at first time as program chair and chair-elect, I Sirtris Pharmaceuticals called upon Aaron Dexter for assistance have continued to explore possible col- Strem Chemicals in constructing furnaces and procuring laborations with area special-interest ZINK Imaging apparatus. Subsequently he secured groups, and am pleased to report that Ziopharm Oncology, Inc. apparatus devised by Robert Hare, and BAGIM (the Boston Area Group for used this kind, ponderous as it was, for Donors ($300-$999) Informatics and Modeling) has ex- many years. One reason he gave for Cambridge-Major Laboratories pressed an interest in formally allying declining to deliver popular lectures Medicilon Inc themselves with NESACS in a manner after 1818 was the necessity of trans- Occidental similar to that of the Medicinal Chem- porting his apparatus by an ox-team. In Organix istry Group. We are also looking into 1820 the Medical School of Bowdoin Peptech Corp the formation of a local Silver Circle College was established and Parker Royal Society of Chemistry group for retired chemists, and former Cleaveland was appointed Professor of SAFC Pharma section chair Pam Mabrouk is explor- Chemistry and Materia Medica. He SAPA-NE ing the possibility of creating a local was soon made Dean of the School. In branch of the Women Chemists’ Com- 1828 his title was changed to Professor mittee. There is a lot going on this year! you with your thoughts and ideas. of Chemistry and Mineralogy. By NESACS as a whole is a vibrant What would make YOU come to a accident he had found some sparkling and active section. This past year, the monthly meeting? Would a different minerals and failing to get satisfactory section received three ChemLuminary day be better? Different time? Differ- information about them from Chaptal’s awards at the national meeting in ent format? We need your perspective; “Chemistry” (the only book available, August, and was runner-up for three after all, it is your section! and still in the library at Bowdoin Col- more. This is an amazing accomplish- You can keep track of upcoming lege), he sent them to Aaron Dexter, ment, and a great deal of credit goes to events by reading The Nucleus.