Planning and Use of Therapeutic Mammoplasty— Nottingham Approach* S.J
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British Journal of Plastic Surgery (2005) 58, 889–901 Planning and use of therapeutic mammoplasty— Nottingham approach* S.J. McCulley*, R.D. Macmillan Breast Reconstruction Service, Departments of Plastic Surgery and Breast Surgery, Nottingham City Hospital, Hucknall Road, Nottingham NG5 1PB, UK Received 4 July 2004; accepted 12 March 2005 KEYWORDS Summary Therapeutic mammaplasty, the use of reduction mammaplasty and Breast cancer; radiotherapy to surgically treat breast cancer, is an established technique for Breast conserving selected breast cancers and can extend the role of breast conserving surgery. Most surgery; frequently described is the use of a wise pattern reduction for tumours that lie within Reduction; the expected mammaplasty excision. However, mammaplasty techniques can be Mammaplasty; safely adapted to treat patients with cancers in all areas of the breast. An approach Therapeutic to selection and planning surgery is presented which has evolved from the experience mammaplasty of other units and our first 50 clinical cases over a 3-year period. The outcomes of these 50 cases are found in the accompanying article. Technique will vary depending upon the tumour position. Breast cancers may lie within the normal excision site of a recognised mammaplasty method (scenario A) or outside of the expected excision sites (scenario B). In scenario A, a range of recognised techniques can be performed without adaptation to widely excise the tumour and re-shape the breasts. In scenario B the techniques need to be adapted. Three decisions are needed for planning in scenario B; the skin incision, the nipple- aereola complex (NAC) pedicle orientation and finally the method of filling the cancer defect. The latter can be achieved by either extending the nipple pedicle or by creating a secondary pedicle within the breast dissection. Either method will move tissue that is normally excised into the cancer defect. For central tumours an inferior pedicle is usually used to both fill the defect and re-create the nipple. q 2005 The British Association of Plastic Surgeons. Published by Elsevier Ltd. All rights reserved. * The long-term oncological safety of breast conser- A smaller version of this article was presented at the Winter BAPS meeting in 2003. This included the clinical outcomes of the ving surgery (BCS) and radiotherapy for selected first 20 patients. The clinical outcomes of the first 50 are now women is accepted.1 The frequency of its use has being prepared in a separate publication. increased in recent years being more common than * Corresponding author. Address: Department of Plastic Sur- mastectomy as a treatment modality in most gery, Nottingham City Hospital, Hucknall Road, Nottingham NG5 1PB, UK. Tel.: C44 115 96 91169x46790; fax: C44 115 96 05216. centres. For the majority of patients a good or E-mail address: [email protected] (S.J. McCulley). excellent cosmetic outcome can be obtained. S0007-1226/$ - see front matter q 2005 The British Association of Plastic Surgeons. Published by Elsevier Ltd. All rights reserved. doi:10.1016/j.bjps.2005.03.008 890 S.J. McCulley, R.D. Macmillan Predictors of poor outcome are tumour position,2 Indications and advantages for especially medial and inferior tumours and the therapeutic mammaplasty amount of breast tissue removed. As the proportion of breast removed increases so the chance of an The advantages are cosmetic and may also be acceptable cosmetic result decreases. Studies have oncological. The core role of therapeutic mam- suggested that depending on tumour site, removing maplasty is to avoid poor cosmetic results from more than 10–20% of the breast may risk an larger resections in breast conserving surgery. It 2 unsatisfactory cosmetic result. This can be associ- is ideal in most mediums to large breasted ated with poor psychological adjustment after woman providing the cancer is suitable for breast 3 breast cancer treatment. Larger percentage exci- conserving surgery. This technique extends the sions are more likely with larger tumours, smaller role of breast conserving surgery by improving breast sizes and surgical preference or protocol for cosmetic outcomes, not by fundamentally chan- quandrantectomy. Many centres now advocate the ging the indications. Patients with extensive DCIS use of oncoplastic techniques to help improve both or multi-focal disease will need treating with a the cosmetic and psychological outcomes in such mastectomy. It may play a role for tumours cases. Oncoplastic techniques available are direct reduced in size following neo-adjuvant treat- 4,5 volume replacement with autologous tissue, or ment.7 The techniques do also have a role in breast reshaping by therapeutic mammaplasty or selected smaller to medium breasted woman, 6–12 local-regional flaps. especially when ptosis is present. Even when Breast reduction techniques have been used in being smaller is not deemed ideal, it may be 6 the management of breast cancer since, the 1980’. preferred by a patient over mastectomy and total We prefer the term therapeutic mammaplasty as it reconstruction. Oncological indications are the avoids confusion over the indications and includes same as for standard breast conserving surgery some variations of technique that are unique to the including tumours up to 4 cm. There is little treatment of breast tumours. Clough et al. has evidence on which to assess the safety of breast- described the largest series of 101 patients over 15- conserving surgery for tumours over 4 cm.15 years and their findings support clinical and Another, more contentious group, include very 7 oncological safety. However, the methods large breasted woman with relatively small tumours described mostly relate to its use in large breasted who would benefit from a reduction mammaplasty patients and using a wise pattern reduction to for quality of life issues as well as having the cancer remove tumours that lie within the expected treated. This latter group are likely to have a good 6–8 mammaplasty excision. This is what we would cosmetic outcome from simple wide local excision describe as scenario A, where the tumour lies within but view reduction mammaplasty as a positive the expected area of excision and no adaptation of outcome of any cancer surgery. However, this technique is required. Losken described using group may have greater morbidity from post- different recognised pedicles for the nipple operative radiotherapy, which can be troublesome depending upon the tumour position.13 He also in large-breasted women.16,17 The homogeneity of discusses use of the pedicle to help fill the tumour the radiation dose, with skipping of areas, may be excision site to improve contour. This enables many less consistent in large breasts.18 tumours to be excised without adapting a known The alternative for many patients to therapeutic method and highlights the advantage of under- mammaplasty is mastectomy and total reconstruc- standing a range of recognised mammaplasty tion, either primary or delayed. In some instances techniques. where radiotherapy after mastectomy is likely, When a tumour lies outside of the expected immediate reconstruction is increasingly not excision site of most recognised mammaplasty advised. This is especially true for any implant techniques (scenario B) other modifications to based reconstruction. Autologous reconstruction mammaplasty techniques are required. Descrip- usually copes far better but can still be affected19 tions of cases do exist to both replace parenchyma (as may a breast treated by therapeutic mammo- and/or skin in such scenarios.14 These have usually plasty). When only one autologous option is involved the creation of secondary pedicles or available it is always a risk to knowingly give extending the breast reduction pillar. By adding to radiotherapy. As therapeutic mammoplasty rep- these options and importantly defining these resents BCS the patient will always be given adaptations over the last 3-years we have found radiotherapy for invasive tumours regardless of the planning of therapeutic mammoplasty is sim- grade, vascular invasion and lymph node status. For plified and its indications extended. such women, therapeutic mammaplasty may be an Planning and use of therapeutic mammoplasty—Nottingham approach 891 ideal option for a cosmetically acceptable result As this is breast conserving surgery radiotherapy from primary breast surgery plus radiotherapy. is required, which can affect the breast over time. The cosmetic outcome from therapeutic mam- This can range from acute changes to skin and maplasty is often similar to reduction mamma- parenchyma to simple volume asymmetry. This is plasty. Although autologous reconstruction can also usually from the nonirradiated breast increasing in give excellent cosmetic outcomes it will not volume to a greater degree than the irradiated ordinarily maintain the same degree of skin or breast. With the complexity of some therapeutic nipple sensation. Recovery from therapeutic mam- mammaplasty procedures it may be expected that maplasty is very similar to standard reduction wound or fat necrosis rates may be higher than mammaplasty and is likely to be quicker than the standard wide local excision. other options stated. Although undoubtably more It was stated under the ‘advantages’ that complicated than simple wide local excision (so patients who will definitely require radiotherapy adding operative time) this technique will avoid may be a good group to consider using therapeutic total reconstruction in many cases, which may