The NIH Record U.S. Department June 12 National of Health, 1979 Institutes Education, and Vol. XXXI of Welfare No. 12 Health

Steroid Use in Breast Cancer DIRECTOR'S AWARDS Will Be Discussed at Consensus Seminar NIH Employees A 3-day consensus development conference of qualitative and quantitative presence of on Steroid Receptors in Breast Cancer will be receptors in breast cancer tissue. held in the Masur Auditorium on June 27, 28, The NIH consensus development confer­ To Be Honored and 29, and is being sponsored by the ence series brings together research scientists, Dr. Donald S. Fredrickson, NIH Director, National Cancer Institute and the Office for physicians, allied health care providers and Medical Applications of Research, NIH. will recognize the outstanding accomplish­ others to assess the safety and efficacy of any ments of various staff members at the 11th The consensus meeting will bring together medical technology in question. more than 50 experts from around the world Annual NIH Honor Awards Ceremony on Past research has indicated that about 40 Monday, June 18, at 1 :45 p.m. in the Masur to clarify the role of steroid hormone recep­ percent of breast cancers have either estrogen tors in determining therapy for breast cancer Auditorium. or other steroid receptors and 60 to 70 and indicating prognosis. The NIH Director's Award will be presented The international group of participants, percent of these tumors are responsive to to 41 Civil Service employees, 2 former NIH under the chairmanship of Dr. Eugene R. therapy by manipulation of these . staff members, and 1 HEW employee, and the DeSombre of the University of Chicago, who The comparative reliabillty of the various PHS Commendation Medal will be presented is also chairman of NCl's Breast Cancer Task methods of tissue analysis for steroid recep­ to 26 Commissioned Officers. The NIH-EEO Award of the Year, the Harvey Force, will examine all facets of the question tors also will be discussed. L. Bullock, Jr. Award for Equal Opportunity Achievements, and 40-Year Length-of-Service Awards also will be presented. Viruses May Cause Some Dr. Fredrickson, assisted by B/ I/ D Directors, will present the awards, and Dr. William F. Raub, NIH Associate Director for Extramural Juvenile Research and Training, will serve as master of ceremonies and read the award citations. Dr. Recovery of a coxsackievirus from the duce the disease; and finally, it must be Philip Handler, President of the National . pancreas of a child who died with acute­ recovered from that diseased animal." Academy of Sciences, will deliver the keynote onset diabetes, and the induction of diabetes The research report by Drs. Ji-Won Yoon, address. in mice with this virus adds support to the Takashi Onodera, and Abner Louis Notkins Music will be provided by the U.S. Air Force theory that some cases of juvenile-onset of NIDR, and Marshall Austin of NNMC in Ceremonial Band. All NIH employees are diabetes may be caused by viruses, according Bethesda, is the first documented instance of invited to attend the ceremony which will last to scientists of the National Institute of Dental the recovery of a virus from the pancreas approximately 1 hour and 30 minutes. Research and the National Naval Medical of a patient with juvenile diabetes. (See Pages 4-8) Center. Their report appeared in the May 24 Since the turn of the century, physicians issue of the New England Journal of Medicine. have suggested that viruses might be one of The journal's editorial sta ted that the new the causes of juvenile diabetes (a different findings come close to fulfilling Koch's postu­ disease from adult-onset diabetes), but solid lates for experimental proof "that an orga­ proof has never been obtained. According to nism causes a disease." His postulates require this theory, viruses produce diabetes by in­ that the "agent must be observed in patients fecting and destroying the beta cells of the with the disease; it must be isolated and pancreas. grown in cul ture; the agent must, when last year, Dr. Notkins and his colleagues inoculated into a susceptible animal, repro- reported that variants of two viruses that are present in the human population could pro­ Prof. Elsen Will Share duce diabetes-like syndromes in mice by His Expertise on Rodin infecting and destroying pancreatic beta cells. At NIH Lecture Tomorrow One of these viruses, reo type 3, is found in the respiratory and digestive tracts, but is not Prof. Albert Elsen will present the NIH thought to produce serious disease. lecture on the artist, Rodin, tomorrow (June The other, Coxsackie 84, causes a variety 13) at 8:15 p.m. in the Masur Auditorium. of illnesses including cold-like symptoms. His lecture is entitled In Rodin's Studio: The (See DIABETES, Page 10) Sculptor and Photographers. Professor Elsen, a leading scholar on A "rilsurei" or standing bow is given by a student Rodin's work, is a Walter A. Hass Professor of to Dr. M.alone prior to their pairing off on an art history at Stanford University. exercise. (See Page 3.) Some Major Parking Changes Effective June 18 The NIH Record JL__.}L_Pl----__.J l__ _ Published biweekly at Bethesda, Md., by the Editorial :&i ;;;; ;:;; 0~c~•-~-•~•-o~•~••~r•o~w~•==•~o•~•===='1i'7--- - , Operations Branch, Division of Public Information, tor the ::::-_:_:- information of employees of the National Institutes of Health, Department of Health, Ed ucation, and Welfare, and ll!VIUD: M•rd'I l , 1977 circulated by request to writers and to researchers in biomedical and related fields. The content is reprintable COtlVENT A~U, w ithout permission. Pictures are available on request. r The NIH Record reserves the right to make corrections, changes, o r deletions in submitted copy in conformity with the policies of the paper and HEW. Denotes parking NIH Record Otllce Bldg. 31, Room 28-03, Phone 496-2125 ■ change

Edllor Frances W. Davis Stall Writer William B. Reinckens

Stall Correopondent• ADA, Judy Fouche; CC, Susan Gerho ld; DCRT, Mary Hodges; DRG, Sue Meadows; DRR, Barbara Menick; DRS, Arthur F. Moore; FIC, George Presson; NCI, Dr. Robert M. Hadsell; NEI, Marsha Corbett; NHLBI, 8111 Sanders; NIA, Ann Dief­ fenbach; NIAlp. Jeanne Winnick; NIAMDD, Diane Naedel; NICHD, Tina McIntosh; NIDR, Sally W ilberding; NIEHS, Hugh J. lee; NIGMS, Wanda Warddell; NIMH, Betty 41 B Zubovic; NINGDS, Doris Parker; NLM, RoJW L. Gilkeson.

June 25 Nomination Deadline " For G.A. Seminar Series This drawing indicates the NIH area where parking changes will be effected. The Ambulatory Care Research Facility Parking Garage is located off Conv2nt Drive where 10-F is shown. June 25 is the deadline date for B/1/D Directors' nominations for the 1979-80 Grants Associates seminar series. These weekly A major parking change will take place, bearing general employee parking permits seminars, beginning in September 1979, will effective next Monday (June 18), in the (blue decals). The entire B-2 level (300 spaces) cover a variety of topics related to extramural Ambulatory Care Research Facility Parking will remain reserved for general employee p rograms. Garage (ACRF), B-1 level; the Multilevel parking. Directors are now being asked to nominate Parking Garage 6 (MLP-6), 3rd level, north • All of lot 10-1 which is presently no more than four candidates for the seminar side; and the parking areas serving Bldgs. 10, reserved for red parking permits will be series rather than the previously announced 30, and 29A: reserved for general employee parking (blue two. • All reserved parking now in lot 10-C will decals). Interested staff members should send their be relocated to the ACRF garage, B-1 level. This includes all preferential, director, CC • Parking areas now reserved for general CV's through their immediate supervisors to employee parking which will be reserved for thei r respective B/1/D Directors, who are volunteer, CC special, and consultant parking spaces. red parking permits are: Bldg. 29A, rear, 11 requested to forward the CV's with a memo spaces; Bldg. 30, front, 19 spaces; Bldg. 29, of endorsement to A. Robert Polcari, execu­ • In the ACRF garage, B-1 level, 116 parking spaces will be reserved for vehicles bearing east stairwell , 6 spaces; and MLP-6, 3rd level, tive secretary of the Grants Associates north side, 50 spaces. Program, Bldg. 31, Rm. 1A-10. red parking permits (red decals). Dr. William F. Raub, Associate Director for • Also, 100 parking spaces will be reserved • All of lots 10-C and 10-D will be reserved Extramural Research, NIH, will make the in .the ACRF garage, B-1 level, for vehicles for outpatient parking. final selection. Brazilian Guitarist Plays Baltimore-Bethesda Bus Makes Trial Run Hispanic Works A 41-seat passenger bus is now running A guitar concert will be given by Brazilian from Baltimore to NIH, Bethesda, Monday virtuoso Carlos Barbos-Lima at the Masur through Friday, for a 2-week trial period Auditorium on Tuesday, June 19, from noon through June 15. to 1 p.m. Arrangements for the bus, which arrives at This 1-hour program will feature music NIH before 8:30 a.m., have been made by a composed by South American composers and group of NIH employees. For more details, is being sponsored by the Hispanic-American call Shirley Gregg, 496-4506. Cultural Committee. Mr. Barbos-Lima was a student of Spain's legendary Andres Segovia and Uruguayan Joint Blood Donor Drive To Be Held guitarist Isaias Savio. He has been praised as June 21 in Westwood Building being "gifted by the goddess of music" by The Clinical Center Blood Bank and the Maestro Segovia. Montgomery County Chapter of the American Since his first U.S. tour in 1967, he has Red Cross will hold a joint summer blood toured with major American.orchestras and drive on Thursday, June 21 , at the Westwood for 3 years was visiting professor and head of Build ing, 5333 Westbard Ave., Bethesda. the guitar program at Carnegie-Mellon Dono rs are asked to d rop by Conf. Rm. D University. He began studying the guitar at 7 from 9:30 a.m. to 3:15 p.m. years of age and gave his first concert debut Carlos Barbosa-Lima is a former student of Segovia. Help out Clinical Center patients and the when he was 12 in Sao Paulo, where he was Washington Metropolitan area. Call the CC born. will be featured as a guest soloist in the Blood Bank, 496-1048, for an appointment This month he will be the first guitarist and Casals Festival in Puerto Rico.

Page2 The NIH Record June 12, 1979 Judo Classes Attract 'Players' For Different Reasons Judo to the uninitiated may appear to be quicker," says Mr. Coleman about his new nothing more than a grappling tug-of-war interest and feels that it offers "more body between two intent contestants across a mat contact than karate." on a gymnasium floor. However, to those who Not all beginning judo enthusiasts are like practice the "gentle way" it is more than a Mr. Coleman and possess a black belt. Most push-and-pull exercise. It is calculated quick­ of the beginners are like Dick Jackson, ness that involves the interaction of mind and Upward Mobility College's project officer. He body. said that he got interested in judo because he Last month, the NIH Judo Club embarked enjoys vigorous physical exercise and mental on establishing its second basic beginner's discipline that judo offers. He considers Dr. course. They hope to eventually develop a Malone's warmup exercises to be "more true "kodokan" or school of judo with a rigorous" than those he went through at the coterie of well-trained "judoka" or students. Army's military police school. The club's "sensi" or teacher, is Dr. Thomas Throughout each class, Dr. Malone is E. Malone, NIH Deputy Director. He holds a assisted by Dianne Moore, a first degree second degree Nidan black belt and is the Shodan black belt, and Taffy Harrison, a second prime mover in communicating the value of degree brown belt. Ms. Moore, Stone Ridge's judo here. For the past 15 years, Dr. Malone physical education teacher, has been involved has studied and taught judo, both in the U.S. in judo for 10 years. She took it up for "fun" and abroad. even though she admits that-she has been A "ritsurei" or ceremonial standing bow is hurt while practicing the sport. She likes the exchanged between players before the begin­ strategic planning that a player has always got ning of each exercise. Dr. Malone, like judo's to be involved with if one "is going to win founder Dr. Jigoro Kano, who in 1882 opened at judo." his Tokyo study center, repeatedly reminds his Original!y, Mrs. Harrison was introduced straining white belt beginning students that to judo by her twin sister, who is also a the goal of judo is to attain maximum effi­ brown belt. She says-as she prepares to ciency with minimum effort for each hold or practice throwing a 180-pound opponent over throw they attempt. Periodically, the club's her shoulder-"! do it for fun, exercise, and students are tested to see if they are ready to mental discipline." Or. Malone completes an over-the-shoulder throw. advance to the next degree of belt. Each player has the opportunity to practice "Judo appeals to all ages,'' said Dr. Malone what they have learned during what is called Anyone interested in trying either judo or about the students in his classes. "It's a sport " randori" or "free practice." Throughout the karate can find instruction with the NIH judo that you have to put your heart and soul exercise, Dr. Malone reminds his students to Club. Every Monday from·6 to 7 p.m., karate into." Dr. Malone became interested in judo "make your body fit the throw." instruction is given by Dr. French Anderson, when his then 8-year-old son, Tom, Jr., started At the end of each lesson players and chief of NHLBl's Laboratory of Molecular taking lessons. instructors face each other in a "zarei" or Hematology. "It's a sport that allows a person to perform kneeling position, and bow their heads in Beginning judo lessons are given on in a totally physical way," and requires the mutual respect and appreciation for allowing Tuesdays from 6 to 7:30 p.m. and run for 12 individual to use "his mind" to think through each other to be used to improve the other's lessons. All classes are held in the "old gym" any of the 40 different major judo throws judo technique. at the Stone Ridge School, adjacent to NIH. and grappling techniques, Dr. Malone noted. He sees a growing interest in judo for "medical reasons." He finds judo to be a "great way to relax," and feels that it is therapeutic in helping to relieve tensions that may build up in a person after spending a full day of work behind a desk. In April, several beginning class members competed in the Third Annual Laurel Invi­ tational Judo Tournament. Among the com­ petitors were Eric Fredrickson, Rajen Koshy, Bill Miller, Mike Schulte, and Robert White. Three additional members of the class dis­ tinguished themselves by winning trophies. In the white belt division, Ann Marie Morgan won first place in the lightweight female division; Carlton Coleman took second place in the men's light middleweight divi­ sion; and Mark Dantzler won second place in the men's light heavyweight brown belt division. Mr. Dantzler was recently examined for and promoted to the highest brown belt rank or "lkkyu." One of the club's new "judoka" or players is Carlton Coleman, a Clinical Center medical technologist. Mr. Coleman is new to the subtleties of judo but not to the oriental martial arts. He holds a Tae Kwon Do karate black belt. "Judo is more controlled and

June 12, 1979 The NIH Record Page3 NIH DIRECTOR'S AWARDS

Dr. Solomon Schneyer, Director, Division of Pro­ gram Analysis, OPPE-"For thoughtful analyses of the useful scope of formal planning !'It NIH, and able advice to the Director, NIH, on difficult program Issues, including research training." NATIONAL CANCER INSTITUTE Leo F. Buscher, Jr., grants management officer, Grants Administration Branch, DCRRC-"For exceptional leadership, unusual administrative Dr. Saunders skill, and unlimited energy in developing and maintaining excellence in grants management during a period of rapid growth and accelerated complexity." Mr. Namovicz Dr. Susan Gottesman, research chemist, Labora­ tory of Molecular Biology, DCBD-"For diligent service on the NIH Recombinant DNA Advisory Mr. Ducker Committee and for invaluable assistance to the NIH Director in revising the NIH Recombinant DNA Guidelines." Dr. Richard A. Grlesemer, associate director for Carcinogenesis Testing Program, DCCP-"For his formulation, direction, and implementation of plans to complete testing on 207 chemicals backlogged from 1976 ... this data presents information to agencies responsible for Ms. Cooke regulatory decisions." Dr. Robert M. Hadsell, head, Reports Section, Dr. Sloan Reports and Inquiries Branch, OCC-"For Indis­ pensable and unwaivering leadership in assuring accurate and responsible reporting of the Mr. Holliday scientific and programmatic activities of the National Cancer Institute."

Dr. Rifkind

Dr. Perpich Dr. Reid

Thomas L Kearns, administrative officer, Admin­ Dr. Schneyer istrative Services Branch, OAM-"For his exceptional ability to anticipate and work out Mr. Buscher creative solutions to NCI-wide administrative OFFICE OF THE DIRECTOR problems." HONORS Dr. Gottesman Dr. Claude B. Klee, research chemist, Laboratory of Bioche,:nistry, DCBD-" ln recognition of Frances W. Davis, Editor, NIH Record, Office ol rigorous and fruitful contributions elucidating Commun/catlons-"For exceptional dedication, complex Interactions between proteins that con­ iudgment, leadership and innovation as Editor of trol Important physiological processes in the the NIH Record for more than a decade." brain." Otis Ducker, Director, Division of Administrative Robert M. Namovlcz, deputy executive officer, Services, OA-"For unusual foresight, expertise Office of Administrative Management-"Fot ma/or and leadership in directing the diverse activities contributions In improving the organizational of the Division of Administrative Services which structure of the National Cancer Institute and for are vital to the research mission of the NIH." valued assistance in initiating the National Toxicology Program." Dr. Zora J. Griffo, special programs officer, Office of the Associate Director for Extramural Research Dr. Griesemer Dr. Joseph F. Saunders, deputy dire,ctor, Office and Training, NIH-"For exceptional leadership of International Affairs, OD-"ln recognition of his in facilitating the development of NIH research superb administrative skill and performance in awards for members of racial and ethnic minority Dr. Hadsell managing lhe USA-USSR Cooperative Scientific groups, women and other soc/ally disadvantaged Collaborative Program in Cancer." individuals." Dr. Margaret H. Sloan, special assistant for R. Ross Holliday, Director, Division of Engineering liaison, DCCR-"For activities In the areas of Services, OA-"ln rec'.lgnition of many years of state-of-the-art definition and consensus develop­ exceptional dedication and exemplary technical ment, Including the preparation of educational and managerial capabilities in administHing the programs and materials for physicians ready for diverse activities of the Division of Engineering implementation." Services." Dr. Joseph G. Perplch, Ass:Jciate Director for NATIONAL HEART, LUNG, Program Planning and Evaluation--"Whose AND BLOOD INSTITUTE personal sk/1/s, training and experience In medicine, the law, and the political process have Mr. Kearns Juanita P. Cooke, chief, Office of Special Con­ been invaluable In the development of procedures cerns, OD-"For her continued efforts in to promote understanding between science and advancing the opportunities of minorities and the public It serves." Dr. Klee women."

Page 4 The NIH Record June 12, 1979 Dr. Clari~ D. Reid, chief, Sickle Cell Disease NATIONAL INSTITUTE Branch, Division of Blood Diseases and Resources-"For her sustained record of accom­ OF NEUROLOGICAL plishment of the mission of the NHLBI and AND COMMUNICATIVE indispensable role In developing the programs of DISORDERS the Sickle C.11 Disease Branch." AND STROKE

Dr. Basil M. Rftklnd, chief, Lipid Anita C. Ley, microbiologist, Section on lmmuno­ Branch, D/Vlsion of Heart and Vascular D/seases­ chemistry and Clinical Investigations, Infectious "For his Innovative, aggressive and enlightened Diseases Branch-"For excellence in Immuno­ leadership In the development and Implementation logical research on Infections which damage the of the National Lipid Research Clinics Program." central nervous system." Dr. Bitten Strlpp, chief, Structure and Function Branch, Division of Lung Diseases-"For effective, Dr. Tyeryar dedicated management of programs to stimulate NATIONAL INSTITUTE fundamental research on lung structure, function OF ARTHRITIS, and development, and to Improve the management METABOLISM, of neonatal respiratory distress syndrome." Dr. Nutter AND DIGESTIVE DISEASES NATIONAL LIBRARY OF MEDICINE Dr. Benjamin T. Burton, associate director for Pro­ Joseph W. Hutchins, computer systems analyst, gram Analysis and Scientific Communicatlons-­ Office of Computer and Communications "For leadership In the initiation and direction ot Systems-"For software development in the the Artificial Kidney, Chronic Uremia Program, MEDLARS System that has substantially Improved NIAMDD." NLM's processing of technical literature." Donald F. Cyphers, flnanclal management officer, Office of Administrative Management-"For NATIONAL INSTITUTE OF unusual talent and resourcefulness in leading the financial management operations of the NIAMDD." ENVIRONMENTAL HEALTH SCIENCES Dr. Burton Dr. James D. McKinney, ch/et, Environmental Chemistry Branch, Research Resources Pro­ gram-"For superior leadership in developing a nationally recognized environmental chemistry Ms. Ley program, and research on assessing chemical structure as a predictive means of defining .,• v.i-.___ :, toxic effects." •. ·' . ,:r ~-- -•_---.,,_--,,_~-;.. ·: ·.'~ ~ ~ ' ,, r;;,,, Dr. Bosma Dr. Berendes

Mr. Cyphers Mr. Clark Mr. Hutchins Dr. Warren T. Piver, chemical engineer, Office of Health Hazard Assessment- "For representing NIEHS on the lnteragency Testing Committee (TOSCA) and his contributions to the World Health Dr. Stripp Organization."

NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES

Dr. WIiiiam P. Allen, Virology Program officer, Ms. Notopoulos Microbiology and Infectious Diseases Program- "For exceptional leadership ab/Illy in coordinating the complex state-of-the-art review of virology Dr. Piver and preparation of a six-vo-lume report." Mr. Bynum Dr. John J. Munoz, head, Allergy and Immunology Section, Rocky Mountain Laboratory-"For Dr. McKinney exemplary research on the immunobio/ogy of components of Bordetella pertuss:s and for his contributions toward the development of an Improved vaccine against whooping cough." - _ _ ;_, Dr. John E. Nutter, chief, Office of Special ' ,·>,•- ..: Research Facilities-"For adminlstrativo skills ,: ",..:c in planning and managing NIA/D's P4 facilities for .. ·. recombinant DNA research and for Initiating and .~~,. ,-•,..,:_- ~ overseeing a complex program of risk assessment and containment." ·~ Dr. Gardner Dr. Munoz Dr. Franklin J. Tyeryar, research microbiologist, Microbiology and Infectious Diseases Program­ "ln recognition of his outst~nding leadership, initiative, and judgment in coordinating Dr. Ballintine epldemiologic and vaccine evaluatlon studies to Dr. Allen prevent and control hepatitis." (Continued on Page 6)

June 12, 1979 The NIH Record Page 5 (Continued from Page 5) NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES

Elward Bynum, director, Minority Access to Research Careers Program-"For contributions to the planning, organization, and administration of the Minority Access to Research Careers Program." Dr. Sara A. Gardner, acting director, Pharmacology-Toxicology Program-"For role in providing creative leadership to the NIGMS Pharmacology-Toxicology Program and contribu­ tions to the NIH Staff Training Extramural Program (STEP) Committee." Dr. Harris

NATIONAL EYE INSTITUTE Dr. Deisseroth

Mr. Presson Dr. Elmer J. Ballintine, clinical director, Intramural Research Program-"For making a listing contribution through his staunch advocacy of applying modern clinical trial methods to the solution of Important eye problems."

NATIONAL INSTITUTE ON AGING

Dr. Gunther L. Eichhorn, chief, Laboratory of Cellular and Molecular Biology, Gerontology Research Center-"For consummate skills as a research chemist and his continuing -contributions to understanding of the interactions of metal Ions Dr. Henney with molecules of biological importance." Or. Friedman

Mr. Kleinman Mr. Lamson

Dr. Kisner Dr. Gonzales Dr. O'Donnell FOGARTY INTERNATIONAL CENTER NATIONAL INSTITUTE George E. Presson (retired), former executive OF DENTAL RESEARCH Mr. Riseberg officer- "For successful role in the design and development of managerial policy and procedures necessary to implement the programs of the Dr. James F. Bosma, chief, Oral Pharyngeal Fogarty International Center." Development Section, Clinical Investigations Branch-"For contributions in the functioning Dr. Joseph R. Quinn, deputy director-"For significance of morphological and sensory effectiveness in providing advice and assistance characteristics in development of the oral and on NIH's international activities, improving a pharyngeal region." knowledge of, and promoting cooperative rela­ tions with other countries."

NATIONAL INSTITUTE DIVISION OF RESEARCH GRANTS OF CHILD HEALTH Mr. Harrison Dr. Mischa E. Friedman, supervisory health AND HUMAN DEVELOPMENT scientist administrator, Scientific Review Branch­ "For demonstrating excellent leadership and Dr. Heinz W. Berendes, chief, Contraceptive Dr. Darby managerial capabilities while assistant chief, Evaluation Branch, Center for Population Clinical Sciences Review, Scientific Review Research-"For scientific skill and administrative Branch, Division of Research Grants." talent in directing the world's only scientific program devoted to evaluating the medical effects Glenn G. Lamson (retired}, former health scientist of contraceptives in use." administrator (Social Sciences), Scientific Review Branch-"For extraordinary service as Executive Secretary of the Epidemiology and Disease Con­ Donald E. Clark, chief, Office of Grants and trol Study Section of the Division of Research Contracts-"For leadership and direction of Grants." NICHD grant and contract management operations which received excellent ratings from two major audits within the past year:' DIVISION OF RESEARCH RESOURCES Janyce E. Notopoulos, program analyst, Office of Planning and Evaluation-"For leadership and Dr. Bachur Dr. Ciriaco Q. Gonzales, director, Minority Bio­ creativity in development of NICHHD research medical Support Program-"For vigorous Initiatives on the prevention of disease and leadership of NIH's major extramural effort In disability." providing biomedical research support to the Dr. Boyd minority academic community." Page 6 The NIH Record June 12, 1979 Dr. JamH F. O'Donnell, deputy director-"For initiating and guiding extramural clinical research continued high quality supervision of the ORR in cancer-related nutritional problems, and for peer review process utilized in five highly demonstrated proficiency in contract differentiated program areas." administration." Larry M. Kleinman, head, Clinical Products Sec­ tion, DCT, NCl-"For sustained and outstanding DEPARTMENT OF HEALTH, performance in the management of investigations/ drug development and production within the EDUCATION, AND WELFARE Division of Cancer Treatment."

Richard J. Rlseberg, NIH Legal Advisor, HEW Dr. Charles E. Myers, head, Biochemical Pharma­ cology Section, DCT, NCl-" For important work Office of General Counsel, Pub/le Health implicating a free radical mechanism in the Division-"For the continuing, valuable role he cardlotoxicity of adiamycin, one of the most has played for the NIH in advising on the legal aspects of the administration of NIH programs." Dr. Castelli effective antineoplastic agents." Dr. David H. Sachs, chief, Transplantation Biology Section, DCBD, NCl-"For major research contributions to the areas of the genetics of the Mr. Garrison ma/or histocompatibility complex, the genetic PHS COMMENDATION control of immune responses, and the nature of lymphoid cell surfaces." MEDALS Dr. Warren Strober, head, lmmunophys/ology Section, DCBD, NCl-"For studies of mechanisms John Harrison, chief, General Construction underlying gluten-sensitive enteropathy and other R. immunologic abnormalities as well as for studies Section, DES, ODA- "For outstanding achieve­ ments In the field of engineering and significant of the regulation of immune responses in disease.'' ' contributions to the profession in providing the increasingly sophisticated facilities required Lawrence A. Trisse/, staff pharmacist, Develop­ for biomedical research." mental Therapeutics Program, OCT, NCl-"ln Dr. Mock recognition of the significant contribution to Dr. Dean W. Darby, chief, Educational Training hospital pharmacy through the publication of a and Consultation Branch, NLM-"ln recognition comprehensive Handbook on Injectable Drugs." of his development of training materials on Information transfer and of innovative systems to Or. Robert C. Young, chief, Medicine Branch, integrate these materials in the health pro­ Dr. Roberts DCT, NCl-"For initiation of a treatment program fessional community." for patients with advanced ovarian cancer and remarkable accomplishment which has resulted today in a 3-fold improvement in response rate and a 6-fold increase in 3-year survival."

Mr. Clemmer 1 Or. Hill

Dr. Sachs Dr. Nicholas R. Bachur, Sr., chief, Laboratory of Dr. Moss Clinical Biochemistry, Baltimore Cancer Research Program, NCl-"For internationally recognized major contributions to our knowledge of the clinical pharmacology of the anthracycline anticancer drugs." Dr. Sogn Dr. Michael R. Boyd, head, Molecular Toxicology Section, OCT, NCl-"For outstanding work which has demonstrated pulmonary activation of a new class of a/kylating agents for furanoterpenes." Dr. Albert B. Deisseroth, head, Experimental Hematology Section, OCT, NCl-"For outstanding research accomplishments in the genetics of hemoglobin synthesis and the field of hematologic supportive care for patients with cancer." Mr. Trissel Dr. Grave Dr. Curtis C. Harris, chief, Human Tissue Studies Section, DCCP, NCl-"For pioneering research on human tissue exp/ant cultures, and for the experimental study of metabolism and interaclions Dr. Strober of chemical carcinogens directly on human Mr. Pijar tissues." Dr. Jane E. Henney, senior investigator, Cancer Therapy Evaluation Program, OCT, NCl-"ln recognition of unusually clear administrative and scientific direction in fulfillin'g duties as project officer of several clinical trials contracts, evaluation of new drugs, and developing new areas of clinical research." Dr. Elaine S. Jaffe, senior investigator, Hemato­ pathology Section, DCBD, NCl-"ln recognition Ms. Wright Dr. Yuspa of clinical and-basic research contributing greatly to present understanding of malignant lymphomas as neoplasms of the immune system." Ms. Wilmer Dr. Daniel L. Kisner, senior investigator, Cancer Dr. Young Therapy Evaluation Program, OCT, NCl-"For (See HONORS, Page 8)

June 12, 1979 The NIH Record Page 7 at the 5' ends of mRNA molecules, and purifying HONORS enzymes that form them." Symposium on Safe Handling (Continued from Page 7) Dr. Dorothy D. Sogn, special assistant to the Of Chemicals Held in Hawaii Director, Immunology, Allergic and Immunologic Dr. Stuart H. Yuspa, chief, In Vitro Pathogenesis Diseases Program, NIAID-"For outstanding A symposium on The Safe Handling of Section, DCCP, NCl-"For developing a model performance and leadership as Executive Chemical Carcinogens, Mutagens and Terato­ for chemically induced neoplastic transformation Secretary, NIAID Task Force on Asthma and In eplthef/al cells and for Innovative studies of gens: The Chemist's Viewpoint was recently Allergic Diseases; exceptional ability and held as a part of the joint Chemical Congress initiation and promotion in carcinogenesis." effectiveness in program responsibilities and coordination." of the American Chemical Society and the Dr. Wlfllam P. Castel/I, medical director, Framing­ Chemical Society of Japan in Honolulu, ham Heart Study, NHLBl-"For leadership in Dr. GIiman 0 . Grave, acting chief, Developmental developing lipid studies In the Framingham Heart Biology and Nutrition Branch, NICHD--"For Hawaii. Study which have elucidated the relation of lipid leadership in Implementing program initiatives The symposium was organized by Dr. fractions to risk of coronary heart disease." and Increased emphasis in support of nutrition Douglas 8. Walters, Technical Programs research during a difficult transition period." Robert J. Garrison, statistician, Epidemiology and manager in the NIEHS Environmental Chem­ Biometry Program, DHVD, NHLBl-"For the Stephen J. Pijar, sanitarian, Biological Control istry Branch and supervisor of its Safety development and application of sophisticated Section, ESB, DRS-"ln recognition of his Office. It was sponsored by the Division of statistical and genetic methodologies to the resourcefulness, perseverance and dedication Chemical Health and Safety and the Division analysis of family and twin studies relating to in coordinating the certification process for the heart disease risk factors." first maximum containment facility for recombinant of Environmental Chemistry, ACS. DNA research." The joint chemical Congress brought to­ Dr. Michael B. M ock, chief, Cardiac Diseases gether nearly 8,000 scientists from the U.S., Branch, DHVD, NHLBl-"For exceptional leader­ ship in the organization, stimulation, and Other Awards Presented Japan, Canada, Australia, and New Zealand. continued central coordination of several ma/or The Safe Handling of Chemical Carcinogens large scale ctinlca/ trials in the area of cardiac The NIH-EEO Award of the Year will be symposium itself involvt?d the presentation of and vascular diseases." presented to Laura R. Wright, a former files 32 papers over a 3-day period. These papers supervisor, Collaborative Prenatal Section, Dr. William C. Roberts, chief, Pathologr. Branch, emphasized the chemist's unique role in DIR, NHLBl-"For distinguished contr,butions to Developmental Neurology Branch, NINCDS­ remedying laboratory safety problems and cardiovascular pathology and spirited leadership "for leadership and outstanding contributions covered six general areas: chemical classifica­ throughout his career which have brought to the implementation of equal employment tion and structure activity predictions; infor­ distinction to the National Institutes of Health opportunity at a/I levels at the NIH." and the Public Health Service." mational needs and resources; laboratory The Harvey J. Bullock, Jr. Award for Equal design, handling and management; chemical Thomas A. Clemmer, computer specialist, Opportunity Achievements will be presented monitoring and medical surveillance; spill Biometry Branch, /RP, NIEHS-"For developing to Juanita J. Wilmer, NCl-"for consistent and highly effective automatic data processing control, decontamination and degradation; capabilities and computer engineering services successful efforts to improve career oppor­ and disposal. for the NIEHS." tunities for fellow employees at the NIH." A book containing many of the symposium Mrs. Bullock will assist in the presentation papers, to be edited by Dr. Walters, is sched­ Dr. James C. HIii, Bacterial Vaccines Pro/act of the award honoring her late husband, a officer, Microbiology and Infectious Diseases Pro­ uled for publication this fall. gram, NIA/D--"For Initiative and leadership In former NIH employee. NIH'ers from the National Institute of successfully directing NIA/D's extramural Forty-Year Length-of-Service Awards will be Environmental Health Sciences, the National bacterial vaccine developmental program." presented to 3 staff members who completed Cancer Institute, the National Heart, Lung, Dr. Bernard Moss, head, Macromolecular Biology 30 years of service during 1978. These are: and Blood Institute, and the Environmental Section, LBV, NIA/D--"For precisely describing John E. Peters, OD; Myrtle R. Eaton, NHLBI; Safety Branch of the Division of Research the vaccinia vlrlon, discovering unique structures and Dr. Benjamin Prescott, NIAID. Services presented papers at the symposium. Dr. Jim Shields Named

He's Dr. Michael l'\.:Bakl'\·. To New NHLBI Posts He Watches one of the worlJ's great · Dr. Jim L Shields has been named associate heart surge, ms. director for review and chief of the Review His Weight He sh,)ulJ know what\ Branch, Division of Extramural Affairs, NHLBI. gouJ for a healthy ht-an. Dr. Shields joined the Institute in 1968 as and an administrator in the Program Projects T akc a wafk instead of Branch, of which he later became chief. From a smoke. there he progressed to chief of the Special HeDoesn't Have thinner dinners. Cut fat from meat. Program Branch, chief of the Review Branch, and assistant director for Prevention, Educa­ Smoke. tion and Control. He has been acting deputy director of the Division of Heart and Vascular Diseases for the past 2 years, and is now serving as interim director. Experience Noted Prior to his arrival at NHLBI, Dr. Shields served as assistant chief of the Physiology Division, U.S. Army Medical Research and Nutrition Laboratory at Fitzsimons General Hospital in Denver. Earlier, he was assistant professor at the University of Missouri School of Medicine in Dr. Michael DeBakey, president of Baylor College of Medicine and a longtime ,advisor to the National Columbia. His research interests include cold Heart, Lung, and Blood Institute, has lent his name and features to a new health education project. acclimatization and the physiologic effects of Transportation Displays, Inc., a space advertising firm, will place 100 of these huge posters in 25 airports, donating the space and posting fees as a public service. A second poster, featuring Dr. Betty Jean Kennedy high altitude on the heart. At NHLBI Dr. of the NHLBI Advisory Council, has also been produced as part of a campaign developed by the NHLBI Shields' work reflects his past interest and he Health Education Branch to present health promotion messages to the public through the transportation has expanded them to include the study of industries. According to TOI, this is the first time a Federal health agency has requested free advertising personality types A and B, and coronary­ space in airports. prone behavior.

Pages The NIH Record June 12, 1979 Belgium Honors Dr. De Meyts George M. Thomas Retires; DRS Satellite Shop Chief For Receptor Research About 150 friends and co-workers recently This month Dr. Pierre De Meyts, a recent attended a retirement party held for George visiting fellow in NIAMDD's Diabetes Branch, M. Thomas, Jr., chief of the Building 10 was selected to receive the prestigious Prix Satellite shop of the Biomedical Engineering des Alumni from Belgium. and Instrumentation Branch, Division of Re­ Two awards are presented every 5 years for search Services. biomedical research, one for clinical investi­ Mr. Thomas, known as "Skip" to his friends, gations and one for basic research. The latter sta.rted work with the U.S. Naval Ordnance award will be given to Dr. De Meyts for his Laboratory, transferring to NI H in 1960. outstanding contributions to research on Prior to this, he served in the United States insulin receptors. Army in the 300th AFA Battalion and in Korea Nominees for the Prix des Alumni must be in 1952 as a tank recovery sergeant. under 35 years of age and are reviewed by Mr. Thomas is a member of the Reserve a jury of experts in the sciences from the Officers Association and had several publica­ Belgian university system. tions and patents while at NIH. This year, Dr. De Meyts was chosen from a Dr. De Meyts works out a problem on an He and his wife, Mary, plan to enjoy camp­ field of 21 candidates in medicine and NIAMDD computer. biology-for his studies on the molecular ing, fishing, gardening, and their two grand­ basis of insulin action, in particular, on the Dr. De Meyts' stay at NIH was interrupted sons, in retirement. physical chemistry of the binding of insulin by his conscription into the Belgian Army in to its receptors on the surface of cells in the July 1976. Discharged as a military physician body. after 15 months, he established his own re­ Dr. De Meyts came to NIH through a search group to continue the work he began fellowship from the Fogarty International at NIAMDD at the International Institute of Center in 1973, and received additional sup­ Cellular and Molecular Pathology in Brussels port from the American Diabetes Association. headed by Nobel prize winner C. de Duve. While at NIH, Dr. De Meyts participated In addition, Dr. De Meyts is a professional in an ongoing NIAMDD Diabetes Branch cartoonist and has captured the flavor of research program on polypeptide hormone Belgian politics in student papers, _posters, receptors. One of the facets of his work is and pamphlets as well as in several published the theory of negative cooperativity: in the booklets. His caricatures have also served to presence of increased amounts of insulin, enliven many a Diabetes Branch meeting with receptor affinity decreases, causing acceler­ his interpretation of scientists at work. ated dissociation of the complex that insulin Educated in Belgium, Dr. De Meyts received forms with its receptor. his M.D. in 1969 from the University of Liege. Although this research focuses on insulin, Dr. De Meyts' wife, Madeleine, has also this regulatory mechanism is applicable to a been at NIH since 1973 and is currently com­ number of different endocrine hormones as pleting a research project as a computational a mechanism for modulating the sensitivity li nguist at the Division of Computer Research of the target cell to hormone action. and Technology. Mr. Thomas plans to enjoy camping, fishing, ga,dening, with his wife, Mary, and their two Dr. Drake To Head grandsons, in retirement. Molecular Genetics Seminar Assesses Toxicological Laboratory Effects of Chemical Agents The National Insti tute of Environmental Dr. John W. Drake, internationally recog­ Health Sciences will hold the second in its nized geneticist, has been appointed chief of se ries of biennial Science Seminars on June the newly fo rmed Laborato ry of Molecular 13-14 at North Carolina State University. Genetics of the National Institute of Envi ron­ The Institute will present its latest fi ndings mental Health Sciences. on the toxicologic effects of the halogenated Dr. Drake joined the Institute in August hydrocarbons, polycyclic hydrocarbons, 1977 and has served as chief of the Molecular dioxin, pentachlorophenol, diethylstil besterol, Genetics Section. noise, nonionizing radiation, and other agents In his new position he w ill serve as the of environmental concern. lnstitute's authority in the area of molecular mechanism of mutation. Dr. Drake is a highly regarded international He will supervise both intramural and geneticist. Dr. Klerman To Speak contract research dealing with molecular On Mental Health Limits mechanisms of mutation induction by chemi­ of Science in Israel and a Guggenheim Fellow cal and physical agents, and biochemical at the Medical Research Council Laboratory The Limits of Mental Health will be steps in repair processes and their influence of Molecular Biology in Cambridge, England. discussed by Gerald L. Klerman, Administra­ on mutational mechanisms. He will also be In 1971-72, he was an NIH Special Fellow in tor, Alcohol, Drug Abuse and Mental Health responsible for related test system develop­ the departmen:t of Mo lecular Biology at the Administration, on Wednesday, June 13, at ment and validation. University of Edinburgh, Scotland. 3 p.m., in Conf. Rm. E, Parklawn Bldg. Dr. Drake graduated frqm Yale Un iversity Dr. Drake is a founding member of the This lecture is a presentation of the Staff in 1954 and received his Ph.D. at the Cali­ International Co mmission for Protection College, NIMH. Dr. Klerman will speak on fornia Institute of Technology, Pasadena, in Against Environmental Mutagens and Car­ what is meant by a "sick society" in light of 1958. cinogens and also a member of the NRC questions that have been raised recently and Among his accomplishments, Dr. Drake was Board of Toxicology and Environmental will explore current research in the mental a Fulbright Fellow at the Weizmann Institute Health Hazards. health field.

June 12, 1979 The NIH Record Page 9 East Coast Consortium Will Research Papers Invited On Basic Mechanisms 'Skin Pigment' Loss Of Cellular Secretion A $2 million research initiative into vitiligo, Besides the emotional impact of a loss of A conference on Basic Mechanisms of a skin pigment loss disease that affects 2 color to a person's skin, there are numerous Cellular Secretion, sponsored by the National million Americans, is being launched because medical problems that can be associated with Institute of Dental Research, will be held of a recently approved NIH 4-year research vitiligo. For example, in a high percentage of Sept. 17-21 at the Annapolis Hilton Inn. grant to a consortium of six east coast research patients, there are abnormalities in the Papers have been invited on seven general centers. pigment cells of the eye: Research has already subjects: activation of the secretory response, The grant, funded by NIAM DD, allows shown that sqme patients with loss of vision the signal hypothesis, post-translational modi­ researchers to look at the different medical due to inflammatory processes, such as fications, transport and packaging in the Golgi and psychological effects of the disease. It uveitis or iritis, may have vitiligo in the pig­ region, translocation of secretory granules, calls for the setting up of a treatment center ment layers of their eyes. exocytosis, and membrane dynamics. at Howard University. Other grant recipients In disorders of autoimmunity-some types In each category, after an introductory are: Yale University, Bryn Mawr College, of hyperthyroidism, adrenal insufficiency, and paper, there will be four papers on current University of Pennsylvania, University of pernicious anemia-the incidence of vitiligo research. An open discussion will complete Massachusetts, Amherst, and Massachusetts is increased approximately 5 to 10 times over the meeting. Eye and Ear Infirmary, Boston. that found in individuals who are in good Because attendance is limited, applications Vitiligo is a disease that affects all races. It health. must be returned by June 15. Inquiries and leaves white patches on the skin; especially Also important is the association of vitiligo requests for applications should be addressed on the face and hands. For the majority of the with melanoma, a cancer of skin pigment to: Patricia Youmans, Laboratory of Biological people who lose pigment, it produces severe cells. Melanoma patients have 10 to 20 times Structure, Bldg. 30, Rm. 211, NIDR, NIH, cosmetic disfigurement. Bethesda, Md. 20205, telephone (301) the normal incidence of vitiligo. Vitiligo patients with light skin, whose 496-5681. patches of depigmentation are not readily Additional information about vitiligo is noticeable, are often upset by their condition. available from the National Institute of However, patients with dark skin may suffer Arthritis, Metabolism, and Digestive Diseases Telephone 'Tommye' Waters serious psychological and social handicaps. Information Office. Retires After 29 Years Thelma (Tommye) Waters, head telephone earlier animal studies, the NIDR group de­ supervisor in the Telephone and Directory DIABETES cided to test the possibility that the virus (Continued from Page 1) Service, OD-OA, retired recently after 29 isolated from the child might produce dia­ years of Government service. Although the coxsackie variant produced betes in mice. They inoculated inbred strains Mrs. Waters started with the NIH Telephone of mice known to be e ither genetically sus­ diabetes in mi ce, the NIDR group found that and Directory Service in 1953 as a telephone it did so onl y in certain inbred strains and ceptible or resistant to virus-i nduced operator. diabetes. that susceptibil ity was genetically controlled Mrs. Waters, a native of North Carolina, The virus isolated from the child produced and inherited as a recessive trait. That is, expects to continue living in Maryland and an infection in all the mice, but the resistant only animals with the right genetic back­ looks forward to traveling and spending more ground developed diabetes when exposed to strains soon recovered without developing time with her friends. She also hopes to do the virus. high levels of sugar in their blood. In contrast, some volunteer work. within 5 days after inoculation, the susceptible In the present study, Dr. Yoon and his At a buffet celebration, she was honored mice became diabetic. Microscopic examina­ colleague recovered a virus from the child's by friends and colleagues who presented her tion demonstrated that many of the insulin­ pancreas and identified it as a variant of with an engraved gold pendant on a chain. At coxsackie 84. A variety of studies including producing beta cells in the pancreas of the diabetic mice had been destroyed, and the the buffet, Mrs. Waters said, "The people I a rise of antibody to the virus during the worked with were not just employees but patient's illness, ruled out the possibility that picture closely resembled the inflammation and destruction of beta cells observed in the dear friends. We worked together as friends the virus was simply a laboratory contami­ to bring about the best possible telephone nant. child's pancreas. Proof that the virus actually was responsible service to NI H employees, patients, visitors, On the basis of information from their for the destruction of the beta cells in mice and the general public." was obtained by coupling a fluorescein dye to antibody made against coxsackievirus and showing that this antibody attached to beta cells within the pancreas of the diabetic, but not the control, mice. The report makes no claim that coxsackie 84 infection is a common cause of diabetes. Quite to the countrary, it points out that close to half the population has at one time or another been exposed to this virus, while less than 1 in 1,000 individuals suffer from juvenile diabetes. Moreover, the scientists know that diabetes can occur in children who have never been exposed to this virus. t Th us, the scientists stress that their case \Cf: might be the exception rather than the rule, and are leaning towards the idea that a \ variety of environmental factors, such as other viruses and chemicals, may trigger diabetes j in genetically predisposed individuals. Vernice Ferguson, chief of the CC Nursing Depart­ However, the investigat0rs hope that the information gath~red from the virologic and ment, recently was the recipient of an Achievement - , Award fot Nursing Services, by the Nursing genetic studies in animals combined with the Education Alumni Association of Teachers College, findings from this case will accelerate research Mrs. Waters cuts the cake at her recent Columbia University. on possible viral etiology of juvenile diabetes. retirement party.

Page 10 The NIH Record June 12, 1979 Frederick J. Gutter Retires HEalthWorks '79 Features Music, From DRG Frede ri ck J. Gutter, assistant chief for Dance and Information research, Referral Branch, DRG, retired on June 2 afte r 34 years of Federal service with 30 of those years spent at NIH. After obtaining degrees from Brooklyn College and Georgetown Univer­ sity, he came to NIH in 1949 as a physical chemist with NCI. Ten years later, he joined the then National Institute of Neurological Dis­ eases and Blindness as a research grants analyst, and in 1961 became a health sci- • entist administrator. Mr. Gutter In 1962, he transferred to DRG as executive secretary of the Communicative Sciences Study Section, a position he held until he was appointed assistant chief for research in 1978. Mr. Gutter's retirement plans incl ude having more time for his hobbies of golf, jogging, and volleyball.

Counseling Hours For Summer Interns Announced Maxie E. Givner, of the Guidance and Counseling Branch, DPM, is the summer Grocery Group performers (top row I to r) were! darence Williams, Sue Taylor, Denise Royal, Richard intern counselor_ If you need assistance come Stanton; (middle row) Harold Carter, Leo Hobbs, Greg Zirzoe, Julie Truss, Elsie Taylor, Janice Bird, Linda to Bldg. 31, Rm. B2C-32, from 9:30 a.m. to. Truitt, Tom Flavin; (bottom row) George Davis, David Ylvisaker, Nancy Low, Anne Ralbovsky, and (not 4 p.m. or call 496-2496. No appointment is shown) Dinah Bertran. necessary.

The NIH Nutrition Exhibit was a highlight of arranged and directed by HEW's Nancy Low. strated how to prevent dental decay. the 3-day HEW-sponsored HEa lthWorks held The fair consisted of a series of "tents" on Sharing the "nutrition" tent were the "food on the Mall on May 22-24, and the "singing specific health topics. Among them was an for thought" and "foods for health" exhibits vegetables" got rave reviews for their part in NIMH "stress tent'' that featured a "relaxation that were sponsored by NHLBI. it. room" and biofeedback equipment. Private groups also sponsored exhibits on The 14-member cast of "singing vegetables" Another tent was set up for health screen- the Mall. " Nutro," a talking robot; a tuna fish performed in costumes that represented ing where people could have their blood sandwich-making contest; a dietary analysis different nutritional foods. To the tunes of pressure and cholesterol checked. A " living computer; a cooking exhibition; and a nutri- various well-known songs, they sang words habits and safety tent" stressed the impor- tional advice corner were also featured that stressed the importance of good health tance of home and automobile safety during HEalthWorks and contributed to ·HEW's through nutrition. The uniquely dressed equipment. In still another tent, NIDR demon- effort for improved public; health. troupe, made up of NIH employees and outside volunteers, was organized and .. directed by Tom Flavin of the NIH News Branch. ~r They performed their 15-minute show several times each day to enthusiastic audi­ ences, and they were featured on a national network television show. The NIH exhibit also featured a "Fat Cell," where the public was tested for obesity on a skinfold measurement device. Visitors walking along the "Eat Right Arcade" saw projected on a screen 46 true-false questions on nutrition. Taped messages about meal choices from a typical American menu were heard at an exhibit restaurant known as the "Eat-Hear Cafe." Throughout the day at the "Breakfast, Lunch, and Dinner Theater," the "Grocery Group" performed their well­ attended health skits. The NIH exhibit was prepared under the sponsorship of the NIH Nutrition Coordinat­ ing Committee chaired by Dr. Artemis Secretary Califano is being interviewed on the importance of good nutrition while members of the Simopoulis. HEalthWorks '79 exhibits were Grocery Group wait to perform.

June 12, 1979 The NIH Record Page 11 Ceremony Formalizes Federal Data- Processing Role for DCRT's Computer Center The Computer Center of the Division of at reasonable costs. Computer Resea rch and Technology officially "Sharing of computing resources also became a Federal Data Processing Center for enables one agency to benefit from software Biomedical and Statistical Computation in a development efforts of other agencies with formal ceremony May 31 at NIH. similar computational needs," said Joseph An interagency agreement, signed by top Naughton, chief of the Computer Center officials from NIH, GSA, and HEW, provides a Branch. "The NIH center has a long record of framework for agreements w ith other Federal both p roviding others with its new develop­ agencies with biomedical or statistical ments and benefiting from developments of computing needs. others." The FDPC agreement applies only to non­ Referring to the importance of computers NIH users. Normal computing services and at NIH, Dr. Arnold W. Pratt, DCRT Director, facilities for NIH users will continue with sa id, " I want to assu re the NIH scientists and significant cost advantages. New users must their leadership that this agreement does not meet the criteria set by the GSA-HEW move DCRT away from its central computing NIH Director Dr. Donald S. Fredrickson (I) and Dr. agreement and be approved by NIH. mission as part of the R&D core of the NIH." Prall meet at the agreement signing ceremonies. "After 2 years of negotiating, this agree­ ment formalizes our long-recorded participa­ tion in the government's ADP sharing NCI-Supported Investigators Honored program. Our technical leadership and participation in the sharing program are, in For Contributions to Cancer Research effect, finally being 'officially' recognized," sa id Henry J. Juenemann, DCRT's assistant Scientists whose work has been supported radiation as a cause of cancer have been d irector. over the years by grants from NIH were supported with more than $15 million in NCI The agreement was made under authority among those who recently received distin­ grants since 1963. given to the GSA. by Congress to arrange for guished new awards for cancer research from Dr. Klein was cited for his pioneering work equipment pools and multiagency sharing, two of the Nation's largest corporations. on the interrelation of cancer and the immune and to establish computing centers. Honored by the General Motors Cancer system in mammalian species, including man . . Such sharing enables small and new agen­ Foundation for their contributions to cancer His work in cell genetics, the possible viral cies to have immediate access to a wide range research were: origins of cancer in man, and cancer cell of tested, specialized computing techniques Dr. Henry S. Kaplan, director of the Cancer metabolism has been supported by more than Biology Research Laboratories, Stanford Uni­ $2 million in NCI funds since the early 1960' s. versity, who received the Charl es F. Kettering Dr. Doll, a specialist in the environmental Phagocyte Chemotaxis Disorders prize; Dr. George Klein, p rofessor of tumor causes of cancer, has done extensive research Topic of Clinical Conference biology, Karolinska Institute, Stockholm, who on the relation between smoking and cancer. Disorders of Phagocyte Chemotaxis is the received the Alfred P. Sloan, Jr., prize; and Drs. Werner and Gertrude Henle received topic at the next Combined Clinical Staff Dr. Richard Doll, regius professor of medicine this year's Bristol-Myers award for their work Conference to be held Thursday, June 14, in and master of Green College, Oxford Uni­ on the Epstein-Barr virus, a virus that causes the Masur Auditorium. versity, England, who received the Charles S. infectious mononucleosis and, they showed, is associated w ith two human cancers. They Dr. John I. Gall in, head, Bacterial Diseases Mott prize. are credited with establishing what may be Section, Laboratory of Clinical Investigation, This was the first year these prizes were the first cause and effect re lationship between NIAID, will moderate the conference. awarded, each carrying a $100,000 honor­ a virus and human cancer. Some $6 million This program has been approved for arium. in NCI grant funds have gone to support this category 1 credit, and all interested NIH'ers Receiving the $25,000 second annual Bristol-Myers Award for Distinguished important work. are urged to attend. Achievement in Cancer Research were Ors. Werner and Gertrude Henle of the Joseph Stokes, Jr., Research Institute, Children's Hos­ pital, Philadelphia. VISITING SCIENTIST Another Bristol-Myers award, for special achievement in advancing cancer research, PROGRAM went to Benno C. Schmidt, chairman of the President's Cancer Panel since 1972. PARTICIPANTS The General Motors and Bristol-Myers awards were established to recognize and 5/21-Dr. Sanzo Miyazawa, Japan, Labora­ stimulate high caliber research and special tory of Theoretical Biology. Sponsor: Dr. contributions i n the prevention and treatment Robert Jernigan, NCI, Bg. 10, Rm. 4BS0. ~~ of cancer thro ughout the world. 5/22- Dr. Daniel Liscia, Italy, Laboratory of 4 Three General Motors and two Bristol­ Pathophysiology. Sponsor: Dr. P. M. Gullino, <' Myers awards will be given each year. The NCI, Bg. 10, Rm. 5836. -~ 5/24-Dr. Inessa Levenbook, Stateless, l' research of this year's recipients reflects the diversity of science sponsored under the Experimental Biology Branch. Sponsor: Dr. First Lady Rosalynn Carter and Dr. Robert N. Butler National Cancer Program . . John Petricciani, BB, Bg. 29, Rm. 513. (c), NIA Director-both of whom recently spoke al Dr. Kaplan was cited for his role in de­ 5/29-Dr. Tsuneo Morishima, Japan, Labora­ the National Conference on Mental Health and the veloping an effective treatment for Hodgkin's tory of Oral Medicine. Sponsor: Dr. Patrick Elderly-p·ose with Rep. Claude Pepper, chair- disease, a cancer of the lymph glands once McClintock, NIDR, Bg. 30, Rm. 124. man of the House Select Committee on Aging. Dr. fatal for nearly all its v ictims. Today, Hodg­ 5/30- Dr. Maria Zeneroli-Baraldi, Italy, Butler urged that geriatrics be incorporated into medical, nursing, social work, and psychology kin's disease is among the most curable Digestive Diseases Branch. Sponsor: Dr. E. A. curricula, and that funds be increased for studies forms of cancer. Jones, NIAMDD, Bg. 10, Rm. 4D52. on senile dementia and related disorders. Mrs. D r. Kaplan's research in the combined use Carter spoke of the inadeGuale mental health care of radiation and chemotherapy in the treat­ received by the Nation's elderly. ment of cancer and his work investigating * U.S. GOVERNMENT PRINTING OFFICE, 197-281-219/20

Page 12 The NIH Record June 12, 1979