Osteoarthritis Tool
Total Page:16
File Type:pdf, Size:1020Kb
Load more
Recommended publications
-
Knee Osteoarthritis
Patrick O’Keefe, MD Knee Osteoarthritis Overview What is knee osteoarthritis? Osteoarthritis, also known as Osteoarthritis is the most common type of knee arthritis. "wear and tear" arthritis, is a common problem for many A healthy knee easily bends and straightens because of a people after they reach middle smooth, slippery tissue called articular cartilage. This age. Osteoarthritis of the knee substance covers, protects, and cushions the ends of the is a leading cause of disability leg bones that form your knee. in the United States. It develops slowly and the pain it Between your bones, two c-shaped pieces of meniscal causes worsens over time. cartilage act as "shock absorbers" to cushion your knee Although there is no cure for joint. Osteoarthritis causes cartilage to wear away. osteoarthritis, there are many treatment options available. How it happens: Osteoarthritis occurs over time. When the Using these, people with cartilage wears away, it becomes frayed and rough. Moving osteoarthritis are able to the bones along this exposed surface is painful. manage pain, stay active, and live fulfilling lives. If the cartilage wears away completely, it can result in bone rubbing on bone. To make up for the lost cartilage, Questions the damaged bones may start to grow outward and form painful spurs. If you have any concerns or questions after your surgery, Symptoms: Pain and stiffness are the most common during business hours call symptoms of knee osteoarthritis. Symptoms tend to be 763-441-0298 or Candice at worse in the morning or after a period of inactivity. 763-302-2613. -
Juvenile Arthritis and Exercise Therapy: Susan Basile
Mini Review iMedPub Journals Journal of Childhood & Developmental Disorders 2017 http://www.imedpub.com ISSN 2472-1786 Vol. 3 No. 2: 7 DOI: 10.4172/2472-1786.100045 Juvenile Arthritis and Exercise Therapy: Susan Basile Current Research and Future Considerations Department of Kinesiology and Health, Georgia State University, IL, USA Abstract Corresponding author: Susan Basile Juvenile Idiopathic Arthritis (JIA) is a chronic condition affecting significant numbers of children and young adults. Symptoms such as pain and swelling can [email protected] lead to secondary conditions such as altered movement patterns and decreases in physical activity, range of motion, aerobic capacity, and strength. Exercise therapy has been an increasingly utilized component of treatment which addresses both Department of Kinesiology and Health, primary and secondary symptoms. The objective of this paper was too give an Georgia State University, USA. overview of the current research on different types of exercise therapies, their measurements, and outcomes, as well as to make recommendations for future Tel: 630-583-1128 considerations and research. After defining the objective, articles involving patients with JIA and exercise or physical activity-based interventions were identified through electronic databases and bibliographic hand search of the Citation:Basile S. Juvenile Arthritis and existing literature. In all, nineteen articles were identified for inclusion. Studies Exercise Therapy: Current Research and involved patients affected by multiple subtypes of arthritis, mostly of lower body Future Considerations. J Child Dev Disord. joints. Interventions ranged from light systems of movement like Pilates to an 2017, 3:2. intense individualized neuromuscular training program. None of the studies exhibited notable negative effects beyond an individual level, and most produced positive outcomes, although the significance varied. -
Variation in the Initial Treatment of Knee Monoarthritis in Juvenile Idiopathic Arthritis: a Survey of Pediatric Rheumatologists in the United States and Canada
Variation in the Initial Treatment of Knee Monoarthritis in Juvenile Idiopathic Arthritis: A Survey of Pediatric Rheumatologists in the United States and Canada TIMOTHY BEUKELMAN, JAMES P. GUEVARA, DANIEL A. ALBERT, DAVID D. SHERRY, and JON M. BURNHAM ABSTRACT. Objective. To characterize variations in initial treatment for knee monoarthritis in the oligoarthritis sub- type of juvenile idiopathic arthritis (OJIA) by pediatric rheumatologists and to identify patient, physi- cian, and practice-specific characteristics that are associated with treatment decisions. Methods. We mailed a 32-item questionnaire to pediatric rheumatologists in the United States and Canada (n = 201). This questionnaire contained clinical vignettes describing recent-onset chronic monoarthritis of the knee and assessed physicians’ treatment preferences, perceptions of the effective- ness and disadvantages of nonsteroidal antiinflammatory drugs (NSAID) and intraarticular corticos- teroid injections (IACI), proficiency with IACI, and demographic and office characteristics. Results. One hundred twenty-nine (64%) questionnaires were completed and returned. Eighty-three per- cent of respondents were board certified pediatric rheumatologists. Respondents’ treatment strategies for uncomplicated knee monoarthritis were broadly categorized: initial IACI at presentation (27%), initial NSAID with contingent IACI (63%), and initial NSAID with contingent methotrexate or sulfasalazine (without IACI) (10%). Significant independent predictors for initial IACI were believing that IACI is more effective than NSAID, having performed > 10 IACI in a single patient at one time, and initiating methotrexate via the subcutaneous route for OJIA. Predictors for not recommending initial or contin- gent IACI were believing that the infection risk of IACI is significant and lacking comfort with per- forming IACI. Conclusion. There is considerable variation in pediatric rheumatologists’ initial treatment strategies for knee monoarthritis in OJIA. -
Joint Pain Or Joint Disease
ARTHRITIS BY THE NUMBERS Book of Trusted Facts & Figures 2020 TABLE OF CONTENTS Introduction ............................................4 Medical/Cost Burden .................................... 26 What the Numbers Mean – SECTION 1: GENERAL ARTHRITIS FACTS ....5 Craig’s Story: Words of Wisdom What is Arthritis? ...............................5 About Living With Gout & OA ........................ 27 Prevalence ................................................... 5 • Age and Gender ................................................................ 5 SECTION 4: • Change Over Time ............................................................ 7 • Factors to Consider ............................................................ 7 AUTOIMMUNE ARTHRITIS ..................28 Pain and Other Health Burdens ..................... 8 A Related Group of Employment Impact and Medical Cost Burden ... 9 Rheumatoid Diseases .........................28 New Research Contributes to Osteoporosis .....................................9 Understanding Why Someone Develops Autoimmune Disease ..................... 28 Who’s Affected? ........................................... 10 • Genetic and Epigenetic Implications ................................ 29 Prevalence ................................................... 10 • Microbiome Implications ................................................... 29 Health Burdens ............................................. 11 • Stress Implications .............................................................. 29 Economic Burdens ........................................ -
Effects of Extracellular Vesicles from Blood-Derived Products on Osteoarthritic Chondrocytes Within an Inflammation Model
International Journal of Molecular Sciences Article Effects of Extracellular Vesicles from Blood-Derived Products on Osteoarthritic Chondrocytes within an Inflammation Model Alexander Otahal 1,* , Karina Kramer 1, Olga Kuten-Pella 2 , Lukas B. Moser 1, Markus Neubauer 1, Zsombor Lacza 2,3, Stefan Nehrer 1 and Andrea De Luna 1 1 Center for Regenerative Medicine, Danube University Krems, 3500 Krems, Austria; [email protected] (K.K.); [email protected] (L.B.M.); [email protected] (M.N.); [email protected] (S.N.); [email protected] (A.D.L.) 2 OrthoSera GmbH, 3500 Krems, Austria; [email protected] (O.K.-P.); [email protected] (Z.L.) 3 Institute of Sport and Health Sciences, University of Physical Education, 1123 Budapest, Hungary * Correspondence: [email protected] Abstract: Osteoarthritis (OA) is hallmarked by a progressive degradation of articular cartilage. One major driver of OA is inflammation, in which cytokines such as IL-6, TNF-α and IL-1β are secreted by activated chondrocytes, as well as synovial cells—including macrophages. Intra-articular injection of blood products—such as citrate-anticoagulated plasma (CPRP), hyperacute serum (hypACT), and extracellular vesicles (EVs) isolated from blood products—is gaining increasing importance in regenerative medicine for the treatment of OA. A co-culture system of primary OA chondrocytes and activated M1 macrophages was developed to model an OA joint in order to observe the effects Citation: Otahal, A.; Kramer, K.; of EVs in modulating the inflammatory environment. Primary OA chondrocytes were obtained from Kuten-Pella, O.; Moser, L.B.; patients undergoing total knee replacement. -
Dynamic Knee Joint Function in Children with Juvenile Idiopathic Arthritis (JIA) Sandra Hansmann1*, Susanne M Benseler1,2† and Jasmin B Kuemmerle-Deschner1†
Hansmann et al. Pediatric Rheumatology (2015) 13:8 DOI 10.1186/s12969-015-0004-1 RESEARCH Open Access Dynamic knee joint function in children with juvenile idiopathic arthritis (JIA) Sandra Hansmann1*, Susanne M Benseler1,2† and Jasmin B Kuemmerle-Deschner1† Abstract Background: Juvenile idiopathic arthritis (JIA) is a chronic illness with a high risk of developing long-term disability. Disease activity is currently being monitored and quantified by ACR core set. Here, joint inflammation is determined; however joint function is the crucial component for developing disability. The aim of this study was to quantify and compare dynamic joint function in healthy and arthritic knee joints and to evaluate response to improvement. Methods: A single center cohort study of consecutive children presenting to the rheumatology outpatient clinic was performed to measure dynamic knee joint function. Serial measures were performed if possible. Splint fixed electrogoniometers were used to measure dynamic knee joint function including ROM and flexion and extension torque. Results: A total of 54 children were tested including 44 with JIA, of whom eight had to be excluded for non-JIA-related knee problems. The study included 36 JIA patients of whom eight had strictly unilateral knee arthritis, and nine controls. Dynamic joint function ROM and torque depended on age and bodyweight, as demonstrated in healthy joints. ROM and torques were significant lower in arthritic compared to unaffected knee joints in children with unilateral arthritis and across the cohort. Importantly, extension torque was the most sensitive marker of impaired joint function. Follow up measurements detected responsiveness to change in disease activity. -
Evaluation of the Limping Child
Current Concept Review Evaluation of the Limping Child Jessica Burns, MD, MPH; Scott Mubarak, MD Rady Children’s Hospital, San Diego, CA Abstract: Prompt evaluation of a younger child (age <5) with gait disturbance or refusal to walk is necessary to distinguish orthopedic urgency (trauma or infection) from relatively benign processes and chronic problems such as arthritis. Physical examination should include evaluation of gait, supine and simulated prone hip examination (on the parent’s lap to keep the child comfortable), and the crawl test. There are six radiographic views of the lower extremities that can assist in the diagnosis. In conjunction with the detailed history, a thorough physical exam, and radiographs from the orthopedic provider can determine the need for laboratory tests and other imaging. Key Concepts: • Evaluation of the limping child begins with a thorough history. • Physical examination of the limping child can be optimized by utilizing the parent to hold the child while the examiner moves the extremities and checks the back. • Six screening radiographs can be obtained to assist in making the correct diagnosis. • Laboratory analysis and magnetic resonance imaging can be obtained if the diagnosis remains elusive. Introduction Evaluation of gait disturbance in the younger child is an symptoms. Utilizing the parent in the physical important skill for the pediatric orthopedic surgeon. examination can help elicit a more detailed examination Although the true incidence is unknown, it is estimated of the child. Focused radiographs can then be utilized to that there are 1.8 per thousand children that will present support a suspected diagnosis. From there, the need for to the pediatric emergency department with complaint of laboratory analysis and further advanced imaging can be gait disturbance. -
Joint Pains UHL Childrens Hospital Guideline
LRI Children’s Hospital Joint Pains in Children Staff relevant to: Children’s Medical and Nursing Staff working within UHL Children’s Hospital Team approval date: March 2019 Version: 2 Revision due: March 2022 Written by: Dr A Sridhar, Consultant Paediatrician/Paediatric Rheumatology Trust Ref: C89/2016 1. Introduction and Who Guideline applies to THIS IS AN AREA WHERE CLINICAL ASSESSMENT IS USUALLY MUCH MORE IMPORTANT THAN “ROUTINE INVESTIGATIONS” SINGLE PAINFUL JOINT The most important diagnosis to consider is SEPTIC ARTHRITIS Can occur: In Any Joint All Age Groups May be co-existing osteomyelitis (particularly in very young) Related documents: Management of the limping child UHL - C13/2016 Septic Arthritis UHL – B47/2017 Differential diagnosis: 1. History of Injury: Traumatic, Acute Joint bleed (May be the first presentation of Haemophilia or other bleeding disorder) - Haemarthroses 2. Significant Fever and Pain: Septic arthritis or Osteomyelitis 3. Recent Viral illness, diarrhoea, Tonsillitis: Reactive Arthritis- 7-14 days after the illness, Fever may not be present 4. History of IBD: Usually monoarthritis of large joints reflects activity 5. Vascultic Rash: HSP or other forms of vasculitis Page 1 of 6 Title: Joint Pains in Children V:2 Approved by Children’s Clinical Practice Group: March 2019 Trust Ref: C89/2016 Next Review: March 2022 NB: Paper copies of this document may not be most recent version. The definitive version is held in the Trust Policy and Guideline Library. 6. Recent Drug ingestion: Serum sickness often associated with Urticarial rash 7. Bone pain, Lymphadenopathy, Hepato-splenomegaly: Leukemia, Lymphoma, Neuroblastoma, bone tumour (h/o nocturnal bone pain) 8. -
Arthritis Patients Follicles Within The
Lymphoid Chemokine B Cell-Attracting Chemokine-1 (CXCL13) Is Expressed in Germinal Center of Ectopic Lymphoid Follicles Within the Synovium of Chronic This information is current as Arthritis Patients of September 26, 2021. Kenrin Shi, Kenji Hayashida, Motoharu Kaneko, Jun Hashimoto, Tetsuya Tomita, Peter E. Lipsky, Hideki Yoshikawa and Takahiro Ochi J Immunol 2001; 166:650-655; ; Downloaded from doi: 10.4049/jimmunol.166.1.650 http://www.jimmunol.org/content/166/1/650 http://www.jimmunol.org/ References This article cites 37 articles, 13 of which you can access for free at: http://www.jimmunol.org/content/166/1/650.full#ref-list-1 Why The JI? Submit online. • Rapid Reviews! 30 days* from submission to initial decision by guest on September 26, 2021 • No Triage! Every submission reviewed by practicing scientists • Fast Publication! 4 weeks from acceptance to publication *average Subscription Information about subscribing to The Journal of Immunology is online at: http://jimmunol.org/subscription Permissions Submit copyright permission requests at: http://www.aai.org/About/Publications/JI/copyright.html Email Alerts Receive free email-alerts when new articles cite this article. Sign up at: http://jimmunol.org/alerts The Journal of Immunology is published twice each month by The American Association of Immunologists, Inc., 1451 Rockville Pike, Suite 650, Rockville, MD 20852 Copyright © 2001 by The American Association of Immunologists All rights reserved. Print ISSN: 0022-1767 Online ISSN: 1550-6606. Lymphoid Chemokine B Cell-Attracting Chemokine-1 (CXCL13) Is Expressed in Germinal Center of Ectopic Lymphoid Follicles Within the Synovium of Chronic Arthritis Patients1 Kenrin Shi,* Kenji Hayashida,2* Motoharu Kaneko,* Jun Hashimoto,* Tetsuya Tomita,* Peter E. -
Indications for Unicompartmental Knee Arthroplasty and Rationale for Robotic Arm–Assisted Technology
A Review Paper Indications for Unicompartmental Knee Arthroplasty and Rationale for Robotic Arm–Assisted Technology Jess H. Lonner, MD results not dissimilar from those of total knee arthroplasty Abstract (TKA), leading to a gradual change in attitude toward UKA. Unicompartmental knee arthroplasty (UKA) is an effec- As long-term data become available, UKA is being more tive surgical treatment for focal arthritis when appropri- universally embraced as a clear and definable treatment ate selection criteria are followed. Although results can option for unicompartmental arthritis. be optimized with careful patient selection and use of a Superb clinical data and desirable kinematic perfor- sound implant design, two of the most important deter- mance support the role of UKA. Berger and colleagues3 minants of UKA performance and durability are how well the bone is prepared and components aligned. Study found that the implant survival rate for 62 consecutive results have shown that component malalignment by as UKAs performed by a skilled surgeon with a design still in little as 2° may predispose to implant failure after UKA. use today was 98% after 10 years and 96% after 13 years, Conventional cutting guides have been relatively inac- using revision and radiographic loosening as the respective curate in determining alignment and preparing the bone endpoints. Emerson and Higgins,4 reporting their personal surfaces for unicompartmental implants. Computer navi- experience with 55 mobile-bearing UKAs, noted a 90% gation has improved component alignment to an extent, rate of 10-year implant survival with progression of lateral but outliers still exist. compartment arthritis as the endpoint and 96% with com- The introduction of robotics capitalizes on the virtues of ponent loosening as the endpoint. -
Hip Osteoarthritis Information
Bòrd SSN nan Eilean Siar NHS Western Isles Physiotherapy Department Hip Osteoarthritis An Information Guide for Patients and Carers Page 1 Contents Section 1: What is osteoarthritis? 3 Contributing factors to osteoarthritis Section 2: Diagnosis and symptoms 5 Symptoms Diagnosis Flare up of symptoms Section 3: Gentle hip exercises for flare ups 7 Section 4: Living with osteoarthritis 8 How with osteoarthritis affect me? What you can do to help yourself Section 5: Range of movement exercises 9 Section 6: Strengthening exercises 10 Other forms of exercise Section 7: Other treatments 13 Living with osteoarthritis Surgery Section 8: Local groups and activities 14 Page 2 What is osteoarthritis? This booklet is designed to give you some useful information following your diagnosis of osteoarthritis. Osteoarthritis is a very common condition which can affect any joint causing pain, and stiffness. It’s most likely to affect the joints that bear most of our weight, such as the hips, as they have to take extreme stresses, twists and turns, therefore osteoarthritis of the hip is very common and can affect either one or both hips. A normal joint A joint with mild osteoarthritis In a healthy joint, a coating of smooth and slippery tissue, called cartilage, covers the surface of the bones and helps the bones to move freely against each other. When a joint develops osteoarthritis, the bones lose their smooth surfaces and they become rougher and the cartilage thins. The repair process of the cartilage is sometimes not sufficient as we age. Almost all of us will develop osteoarthritis in some of our joints as we get older, though we may not even be aware of it. -
Role of Musculoskeletal Ultrasound in Juvenile Idiopathic Arthritis
REVIEW Role of musculoskeletal ultrasound in juvenile idiopathic arthritis Juvenile idiopathic arthritis is a serious autoimmune childhood disease that encompasses several types of chronic arthritis. Diagnosis is largely based on history and physical examination, although imaging modalities may play a role in diagnosis and also guiding management. In the past few years, technological advances in musculoskeletal ultrasound have led to a dramatic increase in the application of ultrasound in diagnosing and monitoring juvenile arthritis and other rheumatologic diseases. This article will review recent publications regarding the use of ultrasound in the diagnosis and treatment of juvenile idiopathic arthritis. 1,2 KEYWORDS: enthesitis n juvenile idiopathic arthritis n steroid injection n synovitis Johanna Chang n tenosynovitis n ultrasound & Alessandra Bruns*2 1Department of Pediatrics, Division of Allergy/Immunology/Rheumatology, Over the past decade, musculoskeletal CT, MRI and also MSK-US may play a role University of San Diego, CA, USA ultrasound (MSK-US) has been described by in diagnosing and managing JIA. Advances 2Ultrasound Clinic, Department of Rheumatology, University of many rheumatologists as the ‘stethoscope’ of in MSK-US have led to more widespread Sherbrooke, Sherbrooke, Canada the joint. Unlike conventional radiography, an interest among pediatric rheumatologists in the *Author for correspondence: established imaging technique for identifying application of US to diagnose JIA and to monitor [email protected] progressive joint damage, US is sensitive to soft the effects of localized and systemic therapy. tissue lesions and can detect early erosive bone This article will review recent publications lesions [1,2] . The development of higher frequency regarding the use of US in the diagnosis and probes (12–18 MHz) and portable US machines treatment of JIA.