What is most important to remember? If you have questions: Strong Internal Medicine • Use this medicine as directed by your doctor Ask your doctor, nurse or pharmacist for more information about rosuvastatin • It is important to continue taking (Crestor®) this medicine even if you feel normal. Most people with high or do not feel sick

• Do not start any new medicines, over-the-counter drugs or herbal remedies without talking to your doctor

• Tell all doctors, dentists and pharmacists that you are using Strong Internal Medicine rosuvastatin (Crestor®) 601 Elmwood Avenue th • Contact your prescriber right away Ambulatory Care Facility, 5 Floor Rochester, NY 14642 if you have severe muscle pain or Phone: (585) 275 -7424 weakness Rosuvastatin Visit our website at: (Crestor®): • Follow the diet and lifestyle www.urmc.rochester.edu/medicine/ - genera medicine/patientcare/ Important Patient Information changes that you talked about l- with your doctor in addition to taking your prescribed medicine to get the greatest health benefits

What does rosuvastatin (Crestor®) do? Who should know I am taking rosuvastatin (Crestor®)? What are some things that I need to be aware of when

• It is used to lower the level of bad cholesterol (LDL), • Keep a list of all your medicines (prescription, natural taking rosuvastatin (Crestor®)? raise the level of good cholesterol (HDL), and lower products, supplements, vitamins, over-the-counter) and • Tell your doctor or pharmacist if you have a “” triglycerides (TG) in the body give it to your healthcare provider (doctor, nurse, nurse allergy, are allergic to rosuvastatin, or if you are allergic • It is used to prevent heart attacks, prevent strokes, and practitioner, pharmacist, or physician assistant) to any other medicines, foods, or substances slow the progression of heart disease Are there any interactions with other drugs that I need • Before using this medicine, tell your doctor or to worry about? pharmacist your medical history, especially if you have How should rosuvastatin (Crestor®) be used? active disease or a rise in liver • Use this medicine as directed by your doctor • There are many drug interactions that may increase your risk of side effects • Call your doctor right away if you have very bad muscle • This medicine is taken one (1) time a day, at the same pain or weakness, or if your turns a muddy brown time each day • Do not start new prescription, over-the-counter medicines, or herbal and dietary supplements without color • Take with or without food. Take with food if it causes an telling your doctor • Avoid or limit alcohol intake (includes wine, beer, and upset stomach What side effects could occur with rosuvastatin liquor) to less than 3 drinks per day • Swallow whole. Do not chew, break, or crush (Crestor®)? • Take antacids that have aluminum or magnesium in What should I do if I forget to take rosuvastatin • Upset stomach, belly pain, hard stools () them at least 2 hours after taking this drug. These (Crestor®)? products can lower absorption of rosuvastatin • Headache • Take the missed dose as soon as you think about it • Tell your healthcare provider if you are pregnant, plan • Weakness • If it is almost time for your next dose, skip the missed on getting pregnant, or if you are breastfeeding. You dose and go back to your normal dose time should not take this medicine while pregnant or breastfeeding • Do not take 2 doses at the same time or extra doses • Use a proper birth control method to prevent

while taking this medicine, since it is harmful in pregnancy If you have any of the following side effects, call your doctor or visit the emergency room • It is important to continue taking this medicine even if immediately: you feel normal. Most people with high cholesterol or • Very bad joint pain or swelling • Signs of liver problems: dark urine, triglycerides do not feel sick upset stomach, light-colored stool, • Any sign of a severe allergic reaction yellowing of skin or eyes • Store in a cool, dry place. Protect from light and do not including: ; ; red, swollen, store in the bathroom • Muscle pain or weakness blistered or peeling skin with or • Keep out of the reach of children and pets • without ; wheezing; tightness of chest or throat; trouble breathing or • Depression talking; swelling of face, lips, tongue • Memory problems or loss or throat • Swelling of hands and feet • Blood in urine