Sleepwalking & Sleep Talking
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S46. Parasomnias.Pdf
PARASOMNIAS S46 (1) Parasomnias Last updated: May 8, 2019 Clinical Features ............................................................................................................................... 2 SLEEP TERRORS (S. PAVOR NOCTURNUS) ............................................................................................... 2 SLEEPWALKING (S. SOMNAMBULISM) .................................................................................................... 3 CONFUSIONAL AROUSALS (S. SLEEP DRUNKENNESS, SEVERE SLEEP INERTIA) ........................................ 3 Diagnosis .......................................................................................................................................... 3 Management ..................................................................................................................................... 3 HYPNIC JERKS (S. SLEEP STARTS) .......................................................................................................... 4 RHYTHMIC MOVEMENT DISORDER ........................................................................................................ 4 SLEEP TALKING (S. SOMNILOQUY) ......................................................................................................... 4 NOCTURNAL LEG CRAMPS ..................................................................................................................... 4 REM SLEEP BEHAVIORAL DISORDER (RBD) ........................................................................................ 4 -
Diagnosing and Treating Common Childhood Sleep Disorders
Gerd R. Naydock, PsyD, LCSW Psychologist, Department of Psychiatry Cooper University Healthcare [email protected] Outline of Presentation Methods used to Study Sleep Neurocognitive Effects of Sleep Disruption Common Sleep Disorders Pediatric Insomnia Obstructive Sleep Apnea Parasomnias Delayed Sleep Phase Disorder Restless Legs Syndrome Sleep in Children with Common Psychiatric Conditions Screening in Primary Care Methods Used to Study Sleep Ambulatory Techniques Edentrace System (monitors pulse, body position, oro-nasal flow, chest impedance, breathing noises, and pulse oximetry) Actigraphy (commonly used, developed in the early 1970s and has come into increasing use in both research studies and clinical practice; allows for the study of sleep-wake patterns and circadian rhythms via the assessment of body movements. The device is typically worn on the wrist and can easily be adapted for home use. Reliable and valid for the study of sleep in normal, healthy populations but less reliable for detecting disturbed sleep) Survey Instruments Many exist for detecting problematic sleep in children and adolescents, including self-report questionnaires (such as the Sleep Disturbance Scale for Children, the Childrens Sleep Habits Questionnaire(CSHQ), and the Child and Family Sleep History Questionnaire), sleep diaries, and parent report forms. Polysomnogram (PSO) Electroencephalogram (EEG) Electromyogram (EMG) Electrooculogram (EOG) Vital Signs Other Physiologic Parameters Function of Sleep Restorative/homeostatic -
Post-Traumatic Stress Disorder (PTSD) and Sleep
SHF-PTSD-0312 21/3/12 6:20 PM Page 1 Post-Traumatic Stress Disorder (PTSD) and Sleep Important Things to Know About PTSD and Sleep • PTSD can happen after a period of extreme trauma and stress. • One of the symptoms of PTSD may be problems with sleeping. • The treatment for this will depend on how the PTSD is affecting sleep. • There are many treatments available. How might PTSD affect sleep? • Insomnia. People with PTSD may have difficulty with getting to sleep or staying asleep. They may wake up There are may sleep problems that may be associated frequently during the night and be unable to get back with PTSD. For more information on the disorders to sleep. mentioned below see the relevant pages on this website. • Issues linked to the body clock, such as Delayed Sleep • The extreme anxiety of PTSD (caused by trauma or Phase Disorder may occur in a person with PTSD. If you catastrophe) can seriously disrupt sleep. In some cases can’t get to sleep until very late at night and then this starts a few months after the event. You might need to sleep in you may be experiencing this suffer from horror or strong fear and feel helpless. See problem. Anxiety and Sleep. • Obstructive Sleep Apnoea may be caused by weight • People with PTSD have higher rates of depression and gain due to the life style changes associated with the this is often associated with poor sleep. See PTSD. If the sleep apnoea is serious, medications such Depression and Sleep. as Seroquel can be an additional danger. -
Sleep Disturbances in Patients with Persistent Delusions: Prevalence, Clinical Associations, and Therapeutic Strategies
Review Sleep Disturbances in Patients with Persistent Delusions: Prevalence, Clinical Associations, and Therapeutic Strategies Alexandre González-Rodríguez 1 , Javier Labad 2 and Mary V. Seeman 3,* 1 Department of Mental Health, Parc Tauli University Hospital, Autonomous University of Barcelona (UAB), I3PT, Sabadell, 08280 Barcelona, Spain; [email protected] 2 Department of Psychiatry, Hospital of Mataró, Consorci Sanitari del Maresme, Institut d’Investigació i Innovació Parc Tauli (I3PT), CIBERSAM, Mataró, 08304 Barcelona, Spain; [email protected] 3 Department of Psychiatry, University of Toronto, #605 260 Heath St. West, Toronto, ON M5T 1R8, Canada * Correspondence: [email protected] Received: 1 September 2020; Accepted: 12 October 2020; Published: 16 October 2020 Abstract: Sleep disturbances accompany almost all mental illnesses, either because sound sleep and mental well-being share similar requisites, or because mental problems lead to sleep problems, or vice versa. The aim of this narrative review was to examine sleep in patients with delusions, particularly in those diagnosed with delusional disorder. We did this in sequence, first for psychiatric illness in general, then for psychotic illnesses where delusions are prevalent symptoms, and then for delusional disorder. The review also looked at the effect on sleep parameters of individual symptoms commonly seen in delusional disorder (paranoia, cognitive distortions, suicidal thoughts) and searched the evidence base for indications of antipsychotic drug effects on sleep. It subsequently evaluated the influence of sleep therapies on psychotic symptoms, particularly delusions. The review’s findings are clinically important. Delusional symptoms and sleep quality influence one another reciprocally. Effective treatment of sleep problems is of potential benefit to patients with persistent delusions, but may be difficult to implement in the absence of an established therapeutic relationship and an appropriate pharmacologic regimen. -
REM Sleep Behavior Disorder Dystonia Essential Tremor Isolated Sleep Paralysis Tourette Syndrome Hypnopompic Hallucinations Hemiballismus Complex Nocturnal Behaviors
Complex Nocturnal Behaviors Alon Y. Avidan MD, MPH Professor & Vice Chair, UCLA Department of Neurology Director, UCLA Sleep Disorders Center Michigan Academy Sleep Medicine (MASM) October 8th, 2016 FACULTY DISCLOSURES: In compliance with ACCME Standards for Commercial Support of CME activities… Alon Y. Avidan I have these relevant financial relationships to disclose: • Merck, Arbor Pharmaceuticals, Pernix: Consulting Fees, Honoraria. • AAN, AASM, CHEST, ACCP, ATS- Educational stipends. • Elsevier, LWW- Book Royalties. Complex Behaviors Around the 24 Clock Restless Legs Syndrome (RLS) Rhythmic Movement Disorders Hypnogogic Hallucinations Disorders of Seizures & RLS Arousal Cataplexy, (Non REM Psychogenic Spells Parasomnias) Nocturnal Seizures PRIMARILY IN WAKEFULNESS REM Nightmares & REDUCED IN REM-related Sleep apnea SLEEP Parkinson’s Disease (“PseudoRBD) Huntington’s Disease Myoclonus Ataxia REM Sleep Behavior Disorder Dystonia Essential Tremor Isolated Sleep Paralysis Tourette Syndrome Hypnopompic Hallucinations Hemiballismus Complex Nocturnal Behaviors Restless Legs Rhythmic Syndrome (RLS) Movement Disorders Disorders of Arousal (Non REM Parasomnias) Nocturnal Seizures REM Nightmares REM-related Sleep apnea (“PseudoRBD) REM Sleep Behavior Disorder Isolated Sleep Paralysis Parasomnias Disorders of Arousal (Non REM Parasomnias) [DDx Nocturnal Seizures] REM Nightmares REM Sleep Behavior Disorder Isolated Sleep Paralysis Sleep Related Movement Disorder Restless Legs Syndrome (RLS) Sleep Starts (Hypnic JerKs) Rhythmic Movement Disorders -
Sleep-Wake Disorders of Childhood
Review Article Address correspondence to Dr Suresh Kotagal, Department of Neurology and Sleep-Wake Disorders the Center for Sleep Medicine, 200 1st St SW, Mayo Clinic, Rochester, MN 55905, of Childhood [email protected]. Relationship Disclosure: Suresh Kotagal, MD, FAAN Dr Kotagal has received personal compensation as chair of the data safety monitoring board for INC ABSTRACT Research, Inc and receives royalties from UpToDate, Inc. Purpose of Review: Sleep-wake disorders occur in 10% to 28% of children and differ Unlabeled Use of somewhat in pathophysiology and management from sleep-wake disorders in adults. Products/Investigational This article discusses the diagnosis and management of key childhood sleep disorders. Use Disclosure: Recent Findings: The role of sleep in memory consolidation and in the facilitation of Dr Kotagal reports no disclosure. learning has been increasingly recognized, even at the toddler stage. Cataplexy, a key * 2017 American Academy feature of narcolepsy type 1, may be subtle in childhood and characterized by transient of Neurology. muscle weakness isolated to the face. Children with obstructive sleep apnea and restless legs syndrome display prominent neurobehavioral symptoms such as daytime inattentiveness and hyperactivity, so it is important to elicit a sleep history when these symptoms are encountered. Systemic iron deficiency occurs in about two-thirds of children with restless legs syndrome and is easily treatable. Parasomnias arising out of nonYrapid eye movement (REM) sleep, such as confusional arousals and sleepwalking, may be difficult to distinguish from nocturnal seizures, and, in many cases, video-EEG polysomnography is required to differentiate between causes. Summary: Clinicians should routinely integrate the assessment of sleep-wake function into their practices of neurology and child neurology because of the opportunity to improve the quality of life of their patients. -
Sleep Disorders As Outlined by Outlined As Disorders Sleep of Classification N the Ribe the Features and Symptoms of Each Disorder
CHAPTER © Jones & Bartlett Learning, LLC © Jones & Bartlett Learning, LLC NOT FOR SALE OR DISTRIBUTION 2NOT FOR SALE OR DISTRIBUTION © Jones & Bartlett Learning, LLC © Jones & Bartlett Learning, LLC NOT FORSleep SALE OR DISTRIBUTION Disorders NOT FOR SALE OR DISTRIBUTION © Jones & Bartlett Learning, LLC © Jones & Bartlett Learning, LLC NOT FOR SALE OR DISTRIBUTION NOT FOR SALE OR DISTRIBUTION © Agsandrew/Shutterstock © Jones & Bartlett Learning, LLC © Jones & Bartlett Learning, LLC NOT FOR SALE OR DISTRIBUTION NOT FOR SALE OR DISTRIBUTION CHAPTER OUTLINE EEG arousal alveolar hypoventilation paradoxical breathing idiopathic central alveolar History of Sleep Disorders© Jones & Bartlett Learning, LLCmicrognathia © Joneshypoventilation & Bartlett Learning, LLC Classification of Sleep DisordersNOT FOR SALE OR DISTRIBUTIONretrognathia NOTsnoring FOR SALE OR DISTRIBUTION Insomnia apnea–hypopnea primary snoring Sleep-Related Breathing Disorders index (AHI) sleep-related groaning Central Disorders of Hypersomnolence respiratory disturbance catathrenia Circadian Rhythm Sleep–Wake Disorders index (RDI) CPAP therapy Parasomnias respiratory effort–related positional therapy Sleep-Related© Jones Movement & Bartlett Disorders Learning, LLC arousal (RERA)© Jones & Bartletttonsillectomy Learning, LLC OtherNOT Sleep FOR Disorders SALE OR DISTRIBUTION upper-airwayNOT resistance FOR SALEadenoidectomy OR DISTRIBUTION Chapter Summary syndrome bi-level therapy excessive daytime multiple sleep latency LEARNING OBJECTIVES sleepiness (EDS) test (MSLT) sudden infant -
Treating the Sleep Disorders of Childhood
89 J. Indian Assoc. Child Adolesc. Ment. Health 2006; 2(3): 89-88 Practice Update Treating the Sleep Disorders of Childhood: Current Practice in the United Kingdom Bartlet LB, MCh, BDCh,DPM,FRCPsych Address for Correspondence: Dr LB Bartlet, 2nd James Terrace, Winchester, UK, S022 4PP, [email protected] ABSTRACT Sleep disorders are common in childhood. Their prevalence is especially high in the presence of disability or chronic illness. They cause considerable stress to the children themselves and to their parents. Sleep deprivation leads to daytime behavioral problems and educational difficulties. In assessing sleep problems thorough history taking is essential. In the majority of cases laboratory technology is not needed. Medication plays a part in the treatment of some syndromes. Behavioral management techniques, applied by the parents, can be very successful. Key Words: Children, Sleep, Disorder, Treatment INTRODUCTION The last quarter century has seen a remarkable growth in our understanding of sleep, its nature, its physiology and related disorders. Studies in the Eighties revealed that, in Western countries at least, young children are particularly prone to disturbances at night. In a community survey, Richman found that 20% of normal 1-2 year olds had sleep problems.1 Mindell suggests that about 25% of children between 1 and 5 years old experience sleep disturbance.2 Though older children appear to have fewer difficulties, a significant proportion of school age children have nocturnal problems. It is also well known that adolescence is characterized by a change in sleep and wakefulness caused by a variety of physiological and psychological factors.3 It suffices to say that such factors as age, maturation, temperament, neurological state, health state (especially upper respiratory infection), mental state, parental health, and environment may contribute to the etiology of child sleep disorders in childhood and adolescence.4 Sleep disorders need to be treated seriously. -
The Co-Occurrence of Sexsomnia, Sleep Bruxism and Other Sleep Disorders
Journal of Clinical Medicine Review The Co-Occurrence of Sexsomnia, Sleep Bruxism and Other Sleep Disorders Helena Martynowicz 1, Joanna Smardz 2, Tomasz Wieczorek 3, Grzegorz Mazur 1, Rafal Poreba 1, Robert Skomro 4, Marek Zietek 5, Anna Wojakowska 1, Monika Michalek 1 ID and Mieszko Wieckiewicz 2,* 1 Department of Internal Medicine, Occupational Diseases and Hypertension, Wroclaw Medical University, 50-367 Wroclaw, Poland; [email protected] (H.M.); [email protected] (G.M.); [email protected] (R.P.); [email protected] (A.W.); [email protected] (M.M.) 2 Department of Experimental Dentistry, Wroclaw Medical University, 50-367 Wroclaw, Poland; [email protected] 3 Department and Clinic of Psychiatry, Wroclaw Medical University, 50-367 Wroclaw, Poland; [email protected] 4 Division of Respiratory Critical Care and Sleep Medicine, Department of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5A2, Canada; [email protected] 5 Department of Periodontology, Wroclaw Medical University, 50-367 Wroclaw, Poland; [email protected] * Correspondence: [email protected]; Tel.: +48-660-47-87-59 Received: 3 August 2018; Accepted: 19 August 2018; Published: 23 August 2018 Abstract: Background: Sleep sex also known as sexsomnia or somnambulistic sexual behavior is proposed to be classified as NREM (non-rapid eye movement) parasomnia (as a clinical subtype of disorders of arousal from NREM sleep—primarily confusional arousals or less commonly sleepwalking), but it has also been described in relation to REM (rapid eye movement) parasomnias. Methods: The authors searched the PubMed database to identify relevant publications and present the co-occurrence of sexsomnia and other sleep disorders as a non-systematic review with case series. -
Adult NREM Parasomnias: an Update
Review Adult NREM Parasomnias: An Update Maria Hrozanova 1, Ian Morrison 2 and Renata L Riha 3,* 1 Department of Neuromedicine and Movement Science, Norwegian University of Science and Technology, N-7491 Trondheim, Norway; [email protected] 2 Department of Neurology, Ninewells Hospital and Medical School, DD1 9SY Dundee, UK; [email protected] 3 Department of Sleep Medicine, Royal Infirmary of Edinburgh, EH16 4SA Edinburgh, UK * Correspondence: [email protected] or [email protected]; Tel.: +44-013-242-3872 Received: 23 August 2018; Accepted: 15 November 2018; Published: 23 November 2018 Abstract: Our understanding of non-rapid eye movement (NREM) parasomnias has improved considerably over the last two decades, with research that characterises and explores the causes of these disorders. However, our understanding is far from complete. The aim of this paper is to provide an updated review focusing on adult NREM parasomnias and highlighting new areas in NREM parasomnia research from the recent literature. We outline the prevalence, clinical characteristics, role of onset, pathophysiology, role of predisposing, priming and precipitating factors, diagnostic criteria, treatment options and medico-legal implications of adult NREM parasomnias. Keywords: NREM parasomnias; slow-wave sleep disorders; parasomnias; adult; arousal disorders; review 1. Introduction Non-rapid eye movement (NREM) parasomnias constitute a category of sleep disorders characterised by abnormal behaviours and physiological events primarily arising from N3sleep [1–3] and occuring outside of conscious awareness. Due to their specific association with slow wave sleep (SWS), NREM parasomnias are also termed ‘SWS disorders’. Behaviours such as confusional arousals, sleepwalking, sleep eating (also called sleep-related eating disorder, or SRED), night terrors, sexualised behaviour in sleep (also called sexsomnia) and sleep-related violence are NREM parasomnias that arise from N3 sleep. -
Confusional Arousals, Sleep Terrors, Sleepwalking and Nightmares
Confusional Arousals, Sleep Terrors, Sleepwalking and Nightmares Confusional Arousal Sleep Terrors Sleepwalking Nightmares Description Children age 6 months to 6 Children between age 6 and Generally children age 6-12 Generally over age 3. years. 14 years. years old. Occur in first third (and occa- Usually occur in first third of the Usually occurs during first Occur during REM (dreaming) sionally middle third) of the night, during a partial arousal third to half of night. sleep. Usually occur in last night during non-REM sleep. from stage four (deep) sleep. half of night. Child appears confused, Child has an expression of May be calm, slow walking or Child often describes dream agitated, “possessed.” Child intense fear, may bolt upright standing. Could be more vigorous but not in detail; he can may progress to crying, with a “blood curdling” scream. with running or screaming when appear frightened, but calms intense thrashing, back Eyes are often wide open with combined with sleep terror episode. in response to reassurance. arching, yet remains asleep. heart racing, sweating, and yet Child has no memory of event, and the child is asleep. does not report a dream. Child often does not Child does not recognize Child may push parent away, Child usually wants parental recognize parents. Child parents, is difficult to may not recognize parents, reassurance. may be difficult to console reassure. or appear to “look through” and may push away from parent. parents. Usually last 2 to 10 minutes May last 2 to 20 minutes. Child often has difficulty Usually last 1 to 10 minutes, and terminate abruptly with going back to sleep, may but can last as long as 40 return to deep sleep. -
Calcium, Magnesium, Potassium, and Sodium Oxybates) Oral Solution in Adult Patients with Idiopathic Hypersomnia at 2021 American Academy of Neurology Annual Meeting
Jazz Pharmaceuticals Presents Phase 3 Study Results of Xywav™ (calcium, magnesium, potassium, and sodium oxybates) Oral Solution in Adult Patients with Idiopathic Hypersomnia at 2021 American Academy of Neurology Annual Meeting April 20, 2021 Xywav demonstrated statistically significant differences in change in Epworth Sleepiness Scale score (p-value <0.0001), Patient Global Impression of Change (p-value <0.0001) and the Idiopathic Hypersomnia Severity Scale (p-value <0.0001) The safety profile in this study was consistent with the known safety profile of Xywav with no new safety signals observed in this population Company to host investor webcast today at 12:30 p.m. ET DUBLIN, April 20, 2021 /PRNewswire/ -- Jazz Pharmaceuticals plc (Nasdaq: JAZZ) today announced positive results from the Phase 3 study of XywavTM (calcium, magnesium, potassium, and sodium oxybates) oral solution in adult patients with idiopathic hypersomnia, which will be presented during the Clinical Trials Plenary Session of the 2021 American Academy of Neurology (AAN) Annual Meeting between 10:00 a.m. and 12:30 p.m. ET. Jazz will host an investor and analyst presentation via webcast today at 12:30 p.m. ET. Today's presentation will further quantify the previously reported Phase 3 top-line results. These additional data were submitted to the U.S. Food and Drug Administration (FDA) in the supplemental New Drug Application that was recently accepted for filing and granted Priority Review. "The efficacy and safety results demonstrate the potential Xywav has for people living with idiopathic hypersomnia, a debilitating, chronic sleep disorder for which there are no approved treatments in the U.S.," said Robert Iannone, M.D., M.S.C.E., executive vice president, research and development and chief medical officer of Jazz Pharmaceuticals.