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R Graphics Output Outgroup virginiae loyaltiensis vaubani kanakinus puillandrei teramachii Profundiconus teramachii2 smirna profundorum neocaledonicus Californiconus californicus sagei Lilliconus traillii traillii2 Pygmaeconus tornata perplexa puncticulata Ximeniconus mindana stearnsii jaspidea ichinoseana longurionis hopwoodi pseudorbignyi comatosa orbignyi comatosa2 Fusiconus coriolisi orbignyi2 elokismenos orbignyi3 elokismenos3 elokismenos2 mcgintyi roberti Dalliconus Conasprella mazei arcuata Kohniconus emarginata delessertii incertae sedis centurio Kohniconus eucoronata Conasprella kimioi n.sp._balerensis alisi Boucheticonus pseudokimioi sieboldii ione Endemoconus somalica memiae pagoda baileyi eugrammata Conasprella boucheti wakayamaensis boholensis boholensis2 distans Fraterconus distans2 gondwanensis luciae stupa darkini acutangulus2 Turriconus acutangulus praecellens miniexcelsus andremenezi andremenezi2 chiangi zonatus imperialis2 imperialis pseudimperialis regius brunneus Stephanoconus bartschi archon cedonulli mappa aurantius curassaviensis pertusus vexillum namocanus rattus Rhizoconus rattus2 miles mustelinus capitaneus klemae sugimotonis Klemaeconus plinthis hirasei litoglyphus litoglyphus2 planorbis2 planorbis striatellus circumactus Strategoconus monile maldivus generalis augur varius2 varius fergusoni Pyruconus patricius tinianus papilliferus balteatus Floraconus anemone3 anemone2 anemone trigonus Plicaustraconus glans granum Leporiconus tenuistriatus hamamotoi capitanellus corallinus martensi troendlei fumigatus alconnelli hughmorrisoni biliosus Splinoconus boeticus viola lenavati tribblei queenslandis shikamai sp2 voluminalis princeps Ductoconus gladiator tabidus Monteiroconus mus vittatus recurvus virgatus sunderlandi burryae anabathrum magellanicus cardinalis arangoi jacarusoi zylmanae poormani cancellatus cancellatus2 Dauciconus villepinii2 villepinii sanderi stimpsoni villepinii3 boui daucus2 hilli amphiurgus massemini granulatus massemini2 daucus leopardus Lithoconus litteratus Elisaconus nussatella Hermes nussatella2 virgo virgo2 Conus terebra coelinae kintoki moreleti Virgiconus moreleti2 avidus frigidus frigidus3 frigidus2 quercinus3 quercinus2 quercinus5 quercinus4 quercinus quercinus6 diadema sanguinolentus Lividoconus lividus conco oridulus muriculatus lischkeanus lischkeanus2 kermadecensis medoci Dendroconus moncuri pergrandis Elisaconus spurius lorenzianus Lindaconus purpurascens Chelyconus ermineus caracteristicus arenatus zeylanicus Puncticulis vautieri arenatus3 arenatus2 sponsalis4 mcbridei nux sponsalis2 nanus Harmoniconus sponsalis musicus2 sponsalis3 musicus dorreensis aristophanes coronatus judaeus taeniatus Virroconus ebraeus miliaris2 encaustus miliaris abbreviatus obscurus geographus Gastridium tulipa cuvieri adamsonii bullatus Textilia kinoshitai bruuni Afonsoconus excelsus striatus gubernator stercusmuscarum occatus circumcisus gauguini2 gauguini Pionoconus striolatus catus magus magus2 consors striolatus2 monachus gigasulcatus sulcatus4 sulcatus3 sulcatus sp3 Asprella jisulcatus rolani sulcatus2 cocceus erythraeensis madecassinus radiatus parius janus ochroleucus nimbosus moluccensis Phasmoconus proximus sutanorcum mucronatus kuroharai australis australis3 armadillo australis2 betulinus glaucus Dendroconus gulinus tessulatus2 tessulatus Tesselliconus eburneus lozeti Plicaustraconus nobilis marchionatus Eugeniconus cordigera marmoreus bandanus Conus marmoreus2 amadis locumtenens Leptoconus locumtenens2 furvus omaria aulicus episcopatus Darioconus pennaceus madagascariensis magnicus aureus crocatus thalassiarchus retifer legatus gloriamaris victoriae2 victoriae Cylinder canonicus dalli ammiralis textile4 textile textile3 textile2 pulcher ateralbus trochulus Kalloconus venulatus venulatus2 mercator guinaicus pineaui dorotheae hybridus lineopunctatus aemulus xicoi allaryi variegatus variegatus2 micropunctatus ventricosus decoratus2 damottai diminutus damottai2 delanoyae3 decoratus borgesi raulsilvai Lautoconus antoniomonteiroi cuneolus2 regonae cuneolus3 cuneolus4 cuneolus maioensis crotchii2 miruchae crotchii3 fuscoavus2 crotchii innitus crotchii4 delanoyae delanoyae2 longilineus serranegrae fuscoavus fuscoavus3.
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  • The Cone Collector N°23
    THE CONE COLLECTOR #23 October 2013 THE Note from CONE the Editor COLLECTOR Dear friends, Editor The Cone scene is moving fast, with new papers being pub- António Monteiro lished on a regular basis, many of them containing descrip- tions of new species or studies of complex groups of species that Layout have baffled us for many years. A couple of books are also in André Poremski the making and they should prove of great interest to anyone Contributors interested in Cones. David P. Berschauer Pierre Escoubas Our bulletin aims at keeping everybody informed of the latest William J. Fenzan developments in the area, keeping a record of newly published R. Michael Filmer taxa and presenting our readers a wide range of articles with Michel Jolivet much and often exciting information. As always, I thank our Bernardino Monteiro many friends who contribute with texts, photos, information, Leo G. Ros comments, etc., helping us to make each new number so inter- Benito José Muñoz Sánchez David Touitou esting and valuable. Allan Vargas Jordy Wendriks The 3rd International Cone Meeting is also on the move. Do Alessandro Zanzi remember to mark it in your diaries for September 2014 (defi- nite date still to be announced) and to plan your trip to Ma- drid. This new event will undoubtedly be a huge success, just like the two former meetings in Stuttgart and La Rochelle. You will enjoy it and of course your presence is indispensable! For now, enjoy the new issue of TCC and be sure to let us have your opinions, views, comments, criticism… and even praise, if you feel so inclined.
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  • Antimycobacterial Activity: a New Pharmacological Target for Conotoxins Found in the First Reported Conotoxin from Conasprella Ximenes
    toxins Article Antimycobacterial Activity: A New Pharmacological Target for Conotoxins Found in the First Reported Conotoxin from Conasprella ximenes Andrea Figueroa-Montiel 1, Johanna Bernáldez 1, Samanta Jiménez 1 ID , Beatrix Ueberhide 2, Luis Javier González 3 and Alexei Licea-Navarro 1,* ID 1 Departamento de Innovación Biomédica, CICESE, Carretera Ensenada-Tijuana 3918, Ensenada, BC C.P. 22860, Mexico; fi[email protected] (A.F.-M.); [email protected] (J.B.); [email protected] (S.J.) 2 Department of Biochemistry and Molecular Pharmacology, New York University, Langone Medical Center, 430 East, 29th Street, New York, NY 10016, USA; [email protected] 3 Laboratorio de Espectrometría de Masas, Departamento de Proteómica, Centro de Ingeniería Genética y Biotecnología, Avenida 31 e/158 y 190, Cubanacán, Playa, P.O. Box 6162, C.P. 10600 La Habana, Cuba; [email protected] * Correspondence: [email protected]; Tel.: +52-646-175-0500 (ext. 27201) Received: 19 December 2017; Accepted: 17 January 2018; Published: 23 January 2018 Abstract: Mycobacterium tuberculosis is the etiological agent of tuberculosis, an airborne infectious disease that is a leading cause of human morbidity and mortality worldwide. We report here the first conotoxin that is able to inhibit the growth of M. tuberculosis at a concentration similar to that of two other drugs that are currently used in clinics. Furthermore, it is also the first conopeptide that has been isolated from the venom of Conasprella ximenes. The venom gland transcriptome of C. ximenes was sequenced to construct a database with 24,284 non-redundant transcripts. The conopeptide was purified from the venom using reverse phase high performance liquid chromatography (RP-HPLC) and was analyzed using electrospray ionization-mass spectrometry (ESI-MS/MS).
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  • The Cone Collector N°20
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  • Cone Snail Fossils the Sample the 28 Fossil Cone Snail Shells Used In
    Cone Snail Fossils The Sample The 28 fossil cone snail shells used in this exercise come from the Plio-Pleistocene fossil record of the southeastern United States. Most of the specimens lived between 2-3 million years ago. Classification Information-- The "Answer" The correct species assignments of the 28 cone snail shells used in this exercise were evaluated by paleontologist Dr. Jonathan Hendricks, who specializes on the fossil record and evolution of this group of snails. Dr. Hendricks recognizes seven (7) different species in this sample. Three belong to the genus Conasprella (Conasprella delessertii, Conasprella marylandica, and Conasprella onisca) and four belong to the genus Conus (Conus adversarius, Conus anabathrum, Conus spurius, and Conus yaquensis). Key features for identifying fossil cone snail species include: the overall shape of the shell, the presence or absence of grooves on the shell, the presence or absence of small bumps near the tip of the shell, and the coloration pattern of the shell, which can sometimes be revealed using ultraviolet light. Links to detailed information about each of the species (including more photographs, including of revealed shell coloration patterns), as well as interactive 3D models, are presented below, along with a key to the "correct" identifications for each one of the cards. Conasprella delessertii (Cards 1, 11, and 23). This species is still alive today. • Neogene Atlas page: http://neogeneatlas.net/species/conasprella-delessertii/ • 3D model: https://sketchfab.com/models/34e2423cb2cf4df498ff6d272e95641f Conasprella marylandica (Cards 13, 21, and 24). This species is extinct and has never been found in Maryland! • Neogene Atlas page: http://neogeneatlas.net/species/conasprella-marylandica/ • 3D model: https://sketchfab.com/models/6d175ee89890444a8049c5aa1ebaeb3f Conasprella onisca (Cards 5, 12, and 26).
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  • Biodiversity of the Genus Conus (Fleming, 1822): a Rich Source of Bioactive Peptides
    • Belg. J. Zool. - Volume 129 (1999) - issue - pages 17-42 - Brussels 1999 BIODIVERSITY OF THE GENUS CONUS (FLEMING, 1822): A RICH SOURCE OF BIOACTIVE PEPTIDES FRÉDÉRIC LE GALL('-'), PHILIPPE FAVREAU('-'), GEORGES RlCHARD('), EVELYNE BENOIT('), YVES LETOURNEUX (') AND JORDI MOLGO (') (')Laboratoire de Neurobiologie Cellulaire et Moléculaire, U.P.R. 9040, C.N.R.S., bâtiment 32-33, 1 avenue de la Terrasse, F-91198 Gif sur Yvette cedex, France ; (')Laboratoire de Biologie et Biochimie Marine, and (')Laboratoire de Synthèse et Etudes de Substances Naturelles à Activités Biologiques, Université de La Rochelle, Pôle Sciences, avenue Marillac, F-17042 La Rochelle cedex, France e-mail: [email protected] Abstract. In this paper, we present an overview of the biodiversity ofboth marine snails of the large genus Conus and their venoms. After a brief survey of Conidae malacology, we focus on the high degree of biodiversity of this gem1s, its specifie biogeography as weil as its habitat, and the relatively strict di et of its members. The venom of Conidae species contains a large number of pep­ tides that can interact selectively with key elements of the peripheral and central nervous systems of vertebrales and invertebrates. Emphasis is on summarizing our current knowledge of the spe­ cifie actions of venom components on ionie channels, receptors and other key elements of cellular communication. The peptides isolated from venoms, called conotoxins, form different families according to both their primary structure and their specifie pharmacological targets . Three. families encompassing the ~-, ~0- and ô-conotoxins target voltage-sensitive sodium channels but with dif­ ferent modes of action or tissue selectivity.
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  • Diversidad De La Comunidad De Moluscos De Fondos Blandos Del Archipiélago Espíritu Santo, Golfo De California, México
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  • Western Atlantic Cones Has Been Long Felt
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