Georgia State University ScholarWorks @ Georgia State University Computer Science Dissertations Department of Computer Science 12-18-2013 Coronary Artery Calcium Quantification in Contrast-enhanced Computed Tomography Angiography Abinashi Dhungel Georgia State University Follow this and additional works at: https://scholarworks.gsu.edu/cs_diss Recommended Citation Dhungel, Abinashi, "Coronary Artery Calcium Quantification in Contrast-enhanced Computed Tomography Angiography." Dissertation, Georgia State University, 2013. https://scholarworks.gsu.edu/cs_diss/80 This Dissertation is brought to you for free and open access by the Department of Computer Science at ScholarWorks @ Georgia State University. It has been accepted for inclusion in Computer Science Dissertations by an authorized administrator of ScholarWorks @ Georgia State University. For more information, please contact
[email protected]. CORONARY ARTERY CALCIUM QUANTIFICATION IN CONTRAST-ENHANCED COMPUTED TOMOGRAPHY ANGIOGRAPHY by ABINASHI DHUNGEL Under the Direction of Dr. Michael Weeks ABSTRACT Coronary arteries are the blood vessels supplying oxygen-rich blood to the heart muscles. Coronary artery calcium (CAC), which is the total amount of calcium deposited in these arteries, indicates the presence or the future risk of coronary artery diseases. Quantification of CAC is done by using computed tomography (CT) scan which uses attenuation of x- ray by different tissues in the body to generate three-dimensional images. Calcium can be easily spotted in the CT images because of its higher opacity to x-ray compared to that of the surrounding tissue. However, the arteries cannot be identified easily in the CT images. Therefore, a second scan is done after injecting a patient with an x-ray opaque dye known as contrast material which makes different chambers of the heart and the coronary arteries visible in the CT scan.