Washington University Record, February 15, 2007

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This Article is brought to you for free and open access by the Washington University Publications at Digital Commons@Becker. It has been accepted for inclusion in Washington University Record by an authorized administrator of Digital Commons@Becker. For more information, please contact [email protected]. Medical News: Genes can 'Blue Song': Lost Tennessee Washington People: Leonard Green influence nicotine dependence Williams poem is published preaches the psychology of learning 8

Feb. 15, 2007 record.wustl.edu Washington University in StLouis Do we have multiple Students argue before Roberts biological clocks?

BY JESSICA MARTIN BY TONY FITZPATRICK

Four finalists in the School of Law's Biologists have discovered a large biological clock in Wiley Rutledge Moot Court Com- the smelling center of mice brains and have revealed petition experienced what most law- that the sense of smell for mice is stronger at night, yers only dream of: arguing before peaking in the nighttime hours and waning during day- Chief Justice of the United States light hours. The study is the first to show that mice have John G. Roberts Jr. multiple biological clocks, opening the possibility that "To be able to argue in front of other mammals — including humans — could, as well. one of the sharpest legal minds in the A team led by Erik Herzog, Ph.D., associate professor country was an experience I will of biology in Arts & Sciences, discovered the clock in the never forget," said Samir Kaushik, a olfactory bulb, the brain center that aids the mouse in second-year law student who argued detecting odors. Results were published in a recent issue the case with teammate and fellow of The Journal of Neuroscience. second-year student Renee Waters at §. ,.-,. ^y; The olfaction biological clock, located in the front of the Feb. 6 competition in the Bryan % v mm the brain directly behind the nose, is hundreds of times Cave Moot Courtroom of Anheuser- larger than the known biological clock called the supra- Busch Hall. chiasmatic nucleus (SCN), located at the base of the "It was an incredible honor to brain. Cells in both the SCN and the olfactory bulb keep argue before Roberts," Waters said. 24-hour time and are normally highly synchronized with "There is no jurist for whom I have each other and with environmental cycles of day-night. greater respect than the chief justice. Samir Kaushik (front left) stands victorious beside fellow School of Law "It's been a question for some time whether the SCN It was an honor to be in his presence student Renee Waters after winning the Wiley Rutledge Moot Court Com- functions as the only biological clock," Herzog said. "One and to engage in dialogue with him petition Feb. 6. The pair successfully argued their case before Chief Jus- wouldn't think that the ability to smell would cycle, but and the four other jurists." tice of the United States John G. Roberts Jr. (back center). that's what we show. Roberts, who presided over the "I think now that the SCN is like the atomic clock — competition, was joined on the panel thought-provoking questions from school has to offer, Waters said. important for keeping central time — and then there are by Karen Nelson Moore, judge on the several different angles." "There is a limit to how much a all of these peripheral clocks for timing tasks like sleep- U.S. Court of Appeals for the Sixth Frazier was pleased that the panel competition like this can simulate re- wake, vigilance, digestion, olfaction, hearing, touch and Circuit; law school alumna Catherine took the competition so seriously. ality, but it's a lot closer to what vision, though not all yet found. It may be that the pe- D. Perry, judge on the U.S. District "The judges weren't throwing out lawyers really do than the typical ripheral clocks are like individual wristwatches that we Court, Eastern District of Missouri; softballs — and that made the whole doctrinal classes," she said. "It gives must periodically reset." David R. Herndon, judge on the U.S. competition a pleasure," he said. us students an idea of how thrilling Perhaps most surprising is the observation that the ol- District Court, Southern District of A student-run Moot Court Board, actually practicing law can be." factory bulb clock can run independent of daily rhythms Illinois; and Richard J. Lazarus, pro- chaired this year by third-year stu- The law school has held moot in sleep-wake or the SCN, making it the Big Ben of the fessor at the Georgetown University dents Brad Keeton and Allison court competitions since its founding mammalian circadian rhythm world. Law Center. Scharf, oversees the annual competi- in 1867. This year's Wiley Rutledge "It seems to be one of those biological clocks that can After making what was described tion and assists in selecting the legal Moot Court Competition began keep running itself for a long time, even without the as a very difficult decision, the panel topic. last fall with preliminary rounds in SCN," Herzog said. named Kaushik and Waters the com- Based on characters from the 2004 which nearly 100 second- and third- Herzog and collaborators Daniel Granados-Fuentes, petition winners. The other final movie "Win a Date with Tad Hamil- year law students participated in two- Ph.D., research associate in biology, and Alan Tseng, a team consisted of third-year students ton," this year's case focused on the person teams. senior majoring in biology, put cedar oil on a cotton James Frazier and Daniel Rhoads. fictitious criminal appeal of a contest Numerous judges and lawyers swab and allowed mice to sniff it for five minutes. "The organizers did a fantastic job winner's boyfriend who allegedly from the local legal community "We then counted the number of olfactory bulb cells bringing together five well-respected threatened a celebrity. served as judges for the various that had been activated by the odorant," Herzog said. jurists to serve on the panel," Kaushik This type of competition is one of rounds of the competition. "The gene cFOS is a marker for cells that were activated said. "We were all challenged with the most valuable experiences the law See Students, Page 6 by the stimulus; we recorded the expression of that gene." See Clocks, Page 6 Turner elected member of prestigious National Academy of Engineering Jonathan S. Turner, Ph.D., the tions accorded to an engineer. Barbara J. and Jerome R. Cox Turner was recognized for his Jr. Professor of contributions to the design and Computer analysis of high-performance Science in the communication networks and was School of among 64 new members elected Engineering & in February, bringing the total Applied U.S. peer-elected membership to Science, has 2,217 of the world's most accom- been elected to plished engineers. the National "Jon's election to the National Academy of Academy of Engineering is a Engineering Turner much deserved recognition of his (NAE). exceptional contributions in re- Election to the NAE is among search, teaching and service to his the highest professional distinc- See Turner, Page 6 Interrupting nerve signals halts disorders

BY JIM DRYDEN February issue of Cell Metabo- lism. Interrupting nerve signals to the "At least in mice, we've shown liver can prevent diabetes and we can prevent the development hypertension in mice, according of diabetes and hypertension by to School of Medicine scientists. interrupting vagal nerve signal- The research team surgically ing," said senior investigator Clay Poetic Construction Bruce Lindsey (right), dean of the College of Architecture and Graduate removed the vagus nerve in mice F. Semenkovich, M.D., professor School of Architecture & Urban Design in the Sam Fox School of Design & Visual Arts, leads a and found the procedure prevent- of medicine and of cell biology group of students in a Renga building workshop Jan. 27-28 in Givens Hall. The workshop was an ed or reversed the development of and physiology. exercise in collaborative building based on Renga, a Japanese poetry form in which 100 people insulin resistance and high blood "We don't know whether the collectively write a poem with one person writing each stanza in succession. Applied to building, pressure in mice primed to devel- same will hold true for humans, student teams had 30 minutes to build something with two two-by-fours. Each successive team op these disorders through treat- but we think somehow altering added to what was built. Ten teams of two students built the structure using only one guideline: ment with glucocorticoids. vagal nerve activity could provide the structure had to be able to be inhabited. Their finding is reported in the See Nerve, Page 6 2 RECORD WASHINGTON UNIVERSITY IN ST. LOUIS Ida Early named secretary to the Board of Trustees

BY ANDY CLENDENNEN University in the late 1970s. Originally from Dallas, Early is Ida H. Early has been named married to Gerald L. Early, Ph.D., secretary to the Board of the Merle Kling Professor of Trustees, announced Chan- Modern Letters, director of the cellor Mark S. Wrighton. Center for the Humanities and The appointment is effective professor of African & African July 1, when Harriet K. Switzer, American Studies, of American Ph.D., steps down from that post. culture studies and of English, all "Harriet Switzer has been a in Arts 8c Sciences. tremendous asset to our Board The couple has two children. and to the University communi- In her role as secretary to the ty," Wrighton said. Board, Early will serve as chief li- "With great dedication and aison between the Board, the Of- special attention to people and fice of the Chancellor and senior issues, she has contributed signif- administrative officers and will be icantly to our improvement responsible for coordinating the throughout her tenure as secre- work of the University's policy- tary to the Board of Trustees," makers. She also will be a Univer- he added. "She will be deeply sity Council member. missed, but we will value her Switzer has served as secretary continued friendship, support to the Board for more than 26 and engagement in the life of the years, working with two chancel- University." lors (Wrighton and Chancellor Emeritus William H. Danforth), Of Early, Wrighton said: "Ida ClOWIling around Elizabeth Grace Wiese, daughter of Eliot Society benefactors Chip and Jane Early brings many years of Uni- seven chairmen of the Board of Wiese, gets her face painted during Eliot Family Night Jan. 26 in the Athletic Complex. The popu- versity experience to her new Trustees and nine presidents of lar annual event for Eliot Society members, their families and guests includes clowns, magicians, role, and I welcome the opportu- the Women's Society (WSWU). a buffet dinner and family activities followed by Bears men's and women's basketball games; nity to work with her. "Transitions are easy when the both teams were victorious that night. More than 740 people attended, setting a Record for partici- "Ida is very familiar with the people involved are such talented, pants. The William Greenleaf Eliot Society is a group of alumni, parents and friends of the Univer- St. Louis community and our intelligent, caring and outstand- sity who provide leadership support for the Annual Fund each year. University and is a person of ing leaders," Switzer said. "Bill enormous ability, sensitivity and Danforth and Mark Wrighton are integrity who I am confident will two of the finest leaders in higher be successful as education. McDonnell Center names new director the next secre- "It's an honor and a privilege tary to the to work with them, as well as BY SUSAN KIIXENBERG MCGINN planetary imagery. trophysics (IIA) for 11 years. Board of with wonderful Board members "Ram Cowsik will build on While the IIAs director, he was Trustees." and with the WSWU board and Ramanath Cowsik, Ph.D., pro- this great legacy, and we are fortu- instrumental in building the Early is the all the terrific WSWU members," fessor of physics in Arts & nate to claim his leadership," Ma- world's highest ground-based ob- senior associate she added. Sciences, has been named direc- cias continued. "He is a highly re- servatory in Hanle, Ladakh, in the director in After earning a bachelor's de- tor of the McDonnell Center for spected physicist who will work to Himalayas. Alumni & De- gree (1957) and a master's degree the Space Sciences effective July 1, help strengthen international rela- Researchers at the McDonnell velopment (1964), both in philosophy from announced Edward S. Macias, tionships within the space science Center and at the IIA are setting Programs, Early Manhattanville College, she Ph.D., executive vice chancellor, community." up two telescopes, one in Hanle where her re- earned a doctorate in philosophy dean of Arts & Sciences and the Considered one of the world's and the other in Arizona — near- sponsibilities include focusing on from Fordham University in Barbara and David Thomas pre-eminent astrophysicists, ly 180 degrees apart in longitude leadership gifts from alumni dur- 1968. Distinguished Professor in Arts 8c Cowsik has made several seminal — for round-the-clock monitor- ing their class reunion years; en- In 1970, Switzer, then a mem- Sciences. and lasting contributions to neu- ing of active galactic nuclei. couraging African-American ber of the Society of the Sacred He will take over from Roger trino physics, gravitation and al- Cowsik, who was inducted into alumni support of the Annual Heart, became president of J. Phillips, Ph.D., professor of most every as- the National Academy of Sciences Fund and other University prior- Maryville College, now Maryville earth and planetary sciences in pect of high-en- in 2004, has received numerous ities; and providing support for University. Arts 8c Sciences, who is stepping ergy astro- awards and honors, including the Danforth Circle (2004) and During her seven-year tenure, down after seven years as direc- physics. He has India's Padma Shri Award, equiva- Patrons (2006) volunteers — she is credited with transitioning tor. contributed to lent to the National Medal of Sci- leadership-giving levels that ac- Maryville from a traditional Cowsik becomes only the the understand- ence; Vikram Sarabhai Award in count for 25 percent of the An- Catholic women's college to an third director of the center since ing of particle Space Sciences; and S.S. Bhatna- nual Fund. independent, co-educational in- it was established in 1975 by a gift physics, cosmic- gar Award in Physical Sciences, "I am thrilled to assume this stitution and also kept the school from aerospace pioneer James S. ray physics, cos- India's most prestigious science new responsibility," Early said. from closing while increasing en- McDonnell. The late Robert M. mology, and prize. "In my 25 years with the Univer- rollment from 340 to 1,200. Walker, Ph.D., the McDonnell gamma and X- Cowsik Phillips came to Washington sity, I have acquired a deep ap- In January 1977, she stepped Professor of Physics, was its inau- ray astronomy. University in 1992 after holding a preciation for our Board of down from Maryville. Later that gural director. Cowsik, whose relationship variety of positions at the Jet Pro- Trustees and its importance in year, the St. Louis Globe-Democ- The center is a consortium of with WUSTL began in 1975 when pulsion Laboratory in Pasadena, Washington University's extraor- rat recognized her as a Woman of WUSTL faculty, research staff Walker invited him to serve as a Calif.; serving as director of the dinary progress. Harriet Switzer Achievement in Education. and students coming primarily distinguished visiting professor at Lunar and Planetary Institute in and her staff have set a high stan- After a year of visiting Sacred from the Arts 8c Sciences depart- the McDonnell Center, joined the Houston; and holding the Mat- dard for service and manage- Heart schools in six countries in ments of Earth 8c Planetary Sci- physics faculty in 2002 as a pro- thews Professorship of Geophysics ment, which I am committed to Asia and two years of "intern- ences and Physics and from the fessor. at Southern Methodist University. maintaining." ships" at Boston College, Radcliffe School of Engineering 8c Applied He earned a bachelor's degree His service to NASA dates to Early came to the University College and Harvard University, Science who are working on the in physics, chemistry and mathe- Apollo 17 in 1972, when he served in 1982, when she started at the she returned to St. Louis in 1980 cutting edge of space research. matics, with minors in English as team leader of the Apollo John M. Olin School of Business where she joined WUSTL and be- "The McDonnell Center for and Sanskrit, at the University of Lunar Sounder experiment. He as an administrative assistant. came assistant secretary and assis- the Space Sciences has benefited Mysore in India in 1958. He is deputy team leader for the From there, she progressed to tant to the chancellor. from a strong tradition of excel- earned a master's degree in SHARAD Sounding Radar Inves- student relations coordinator In 1981, she was named secre- lence begun by founder Bob physics at India's Karnatak Uni- tigation on the Mars Reconnais- (1983-84) and, in 1984, was pro- tary to the Board of Trustees; in Walker," Macias said. "It has con- versity in 1960 — at age 19 — sance Orbiter mission. moted to director of special proj- 1986, she also became University tinued to prosper under Roger and then a doctorate in physics in Phillips plans to retire from ects in the business school. coordinator of the Women's So- Phillips, who has very capably led 1968 from the University of Bom- WUSTL at the end of 2007. He From 1993-96, she served as ciety. the center since 1999. bay while working at the Tata In- and his wife, Rosanna Ridings, director of development and In 1992, she married David L. Under Phillips' direction, col- stitute of Fundamental Research. will make their home in Boulder, alumni programs in the School Cronin, now retired associate dean laborative research continued in He taught and did research for Colo., where he will continue his of Art and director of develop- of the social work school; they such fields as astrophysics, extra- more than 40 years at the Tata In- research activities in affiliation ment for the Gallery of Art. have three children and three terrestrial materials, planetary stitute, where he served as direc- with the Southwest Research In- She took a sabbatical from the grandchildren. geophysics/geochemistry and tor of the Indian Institute of As- stitute. University in 1996 to serve as president of the Junior League of St. Louis from 1996-98, then returned to the University as direc- Join an interactive television series on The Big Read tor of annual giving programs in The higher education cable station HEC-TV Student program, 9-10 a.m. Feb. 20; evening Day programs will air Alumni & Development Pro- is sponsoring a series of interactive, partici- program, 7-7:30 p.m. Feb. 21. This program ex- live in the St. Louis region grams, a position she held until patory television programs related to The Big plores the political and governmental themes of on HEC-TV and via video 2001. Read, a University-sponsored initiative of the "Fahrenheit 451," including censorship, free conferences and on the From 2001-02, she was inter- National Endowment for the Arts designed to speech and governmental power, and how they Web at hectv.org. During im director of the parents' pro- restore reading to the center of American cul- resonate in modern society. the programs, viewers can gram at Duke University. She re- ture. The station is looking to include literary • Technology, Privacy and "Fahrenheit 451." e-mail questions to turned to WUSTL to her current experts and political and social scientists from Student program, 9-10 a.m. Feb. 27; evening [email protected]. position in 2002, then served as the University faculty on the programs' discus- program, 7-7:30 p.m. Feb. 28. In discussing the Evening programs will air live on HEC-TV. interim director of development sion panels. role of technology in the book and in today's Community members also can watch at inter- for the George Warren Brown Through the series — and other events — society, this program looks at the toll technol- active video conference locations for face-to- School of Social Work from participants in the community reading project ogy can take on privacy. David A. Lawton, face interaction with program participants. 2005-06. will discuss the provocative themes of Ray Ph.D., professor and chair of the Department E-mail and phone questions will be accepted Early earned a bachelor's de- Bradbury's 1953 novel "Fahrenheit 451." of English in Arts 8c Sciences, will join other during evening programs. gree in sociology from the Uni- Beginning Feb. 20, the television series of- panelists during the evening program, which is For more information on video conference versity of Pennsylvania in 1974 fers day and evening programming for school available via a live video conference at the St. locations or to be part of a live audience, call and did graduate study in educa- students, teachers, parents and the community. Louis County Library headquarters at 1640 S. 531-4455. For more information on The Big tional administration at Cornell • Politics, Government and "Fahrenheit 451." Lindbergh Blvd. Read, visit bigread.wustl.edu.

r V record.wustl.edu WASHINGTON UNIVERSITY IN ST. LOUIS Feb. 15,2007 3 School of Medicine Update Nicotine dependence linked to DNA regions, studies show ' ■\- ^ J^K

BY JIM DRYDEN '^HBtfH ^I Although Americans are bombarded with anti- "An imbalance between excitatory fc* i'L smoking messages, at least 65 million continue and inhibitory activity in the brain may to light up. Genetic factors play an important role in this continuing addiction to cigarettes, School predispose people to addiction, such as of Medicine scientists suggest. alcoholism, drug dependence or nicotine IMB In two studies in the January 2007 issue of dependence. The Neurexin gene we've Human Molecular Genetics, the scientists show that certain genetic variations can influence smoking be- identified is really a key factor in the haviors and contribute to a person's risk for nicotine balance between inhibition and dependence. The smoking-related genes identified facilitate excitatory activity in neurons." communication between nerve cells in the brain. LAURA JEAN BIERUT One gene in particular, the alpha-5 nicotinic cholin- ergic receptor (CHRNA5) gene, was a strong indica- tor of risk for nicotine dependence. Individuals with Dependence, is a U.S.-based sample that includes a specific variation in the gene both addicted smokers and "social" smokers from St. seemed to have a two-fold increase Louis, Minneapolis and Detroit. The other is an Aus- of developing nicotine dependence tralian study of smokers of European ancestry called once exposed to cigarette smoking. the Nicotine Addiction Genetics study. CHRNA5 is from a class of recep- The scientists combined two approaches for ana- tors that plays a role in dopamine lyzing genetic information. One approach scanned pathways in the brain, which are the entire human genome for suspicious areas of linked to a person's experience of DNA, while the second approach closely examined pleasure. specific target genes. The researchers also identified Bierut "The combination of these two approaches repre- genes related to gamma aminobu- sents the most powerful and extensive study on nico- tyric acid (GABA) receptors, an- tine dependence to date and is an important step in a J J other set of proteins vital to nerve cell function. Both large-scale, genetic examination of nicotine depend- Vive le Tango! Herbert Bilinsky practices the tango with GABA and nicotinic receptors had been suspected of ence," said Elias A. Zerhouni, M.D., director of the Madeleine Hackney, a movement science doctoral student and involvement in nicotine addiction, but these findings National Institutes of Health, which funded the stud- a former professional dancer, while Gammon Earhart, Ph.D., strengthen those suspicions. ies. "As more genomic variations are discovered that assistant professor of physical therapy, looks on. Each week The studies also identified a gene not previously are associated with substance abuse, we can better Earhart and Hackney offer tango lessons to patients with Park- known to be involved with nicotine dependence. understand addictive disorders." inson's disease and their partners. The lessons started last summer as part of a pilot study, funded by the American Park- Called the Neurexin 1 gene, it helps regulate the bal- The researchers identified an area of DNA varia- inson Disease Association, examining the effects of tango on ance between excitatory mechanisms — those that tion that seems to alter the function of a nicotinic re- walking and balance in people with Parkinson's disease and in increase communication between nerve cells — and ceptor protein. That small variation makes a big dif- those without the disease. The improvements in the Parkin- inhibitory mechanisms — those that slow firing be- ference in risk for nicotine dependence. son's patients who took the summer tango lessons were so tween nerve cells. Current drug treatments for nicotine dependence marked that Earhart has applied for additional grant support "An imbalance between excitatory and inhibitory are only marginally successful, and Bierut said using to continue the program. activity in the brain may predispose people to addic- information about genetic traits to tailor medica- tion, such as alcoholism, drug dependence or nico- tions to individuals could make them significantly tine dependence," said Laura Jean Bierut, M.D., asso- more effective. "The type of variant you have at this ciate professor of psychiatry and principal investiga- particular receptor — the alpha-5 nicotinic receptor Memorial service to be held for Karls tor of both studies. "The Neurexin gene we've identi- — may actually predict whether or not you will do ■ Jlichael M. Karl, M.D., and Irene um at the Farrell Learning and fied is really a key factor in the balance between inhi- well on nicotine-replacement therapy," she said. IE. Karl, Ph.D., were pioneers in Teaching Center. bition and excitatory activity in neurons." Bierut said it's important to find genetic factors their fields of medicine, mentors to Michael Karl, widely recog- Bierut said she suspects many genes are involved in related to nicotine dependence because so much of generations of physicians and sci- nized as one of the country's nicotine dependence and said understanding how they the population continues to smoke, in spite of the entists and among the most influ- outstanding general internists, work may make it possible to develop new treatments overwhelming evidence that it's harmful. And she ential couples at the School of died Nov. 22, 2006, at age 91. to help people quit smoking. said she believes some of the genes her research team Medicine. Irene Karl, a pioneer in the The research team analyzed data from almost has identified will help scientists develop therapies In honor of their impact on the cause and treatment of sepsis 2,000 participants in two ongoing studies. One, for smokers who just can't seem to quit with existing medical school community, a me- and a trailblazer among women called the Collaborative Genetic Study of Nicotine treatments. morial service will be held at 4:30 in science, died July 7, 2006, at p.m. Feb. 23 in Connor Auditori- age 90.

Kharasch named Shelden Professor Older adults needed for memory study BY JIM DRYDEN viduals such as Dr. Kharasch and the Sheldens enables us to more to support their important con- fully support and maintain Dr. BY JIM DRYDEN Genetics in Psychiatry and pro- Evan D. Kharasch, M.D., Ph.D., tributions to research and educa- Kharasch's major contributions fessor of genetics and of neurolo- has been named the Russell D. tion." in translational anesthesiology re- School of Medicine researchers gy, and Mark A. Mintun, M.D., and Mary B. Shelden Professor of Russell Shelden served on the search and thereby enhance and are conducting a study to inves- professor of radiology and of psy- Anesthesiology. clinical faculty in the Department maintain our department's pre- tigate factors related to memory in chiatry. This is the second anesthesiol- of Anesthesiology at the Universi- eminent position in anesthesiolo- older adults. They are seeking Participants and their sibling ogy professorship established at ty of Missouri from 1958-1983. gy research," Evers said. healthy volunteers between 70 and volunteers must be within four the School of Medicine through He spent most of his medical ca- Kharasch directs the anesthe- 75 years of age who have siblings years of one another's age. The gifts from the Sheldens. The first reer at Research Medical Center siology department's Division of also willing to participate. presence of metal in the body, such was endowed in 1998. in Kansas City, where he served as Clinical and Translational Re- Study participants will undergo as pacemakers or prosthetic de- Russell Shelden is an anesthesi- president of the staff and received search. He came to WUSTL in a magnetic resonance imaging vices, may exclude some subjects. ologist and graduate of the School the Medical 2005 from the University of scan to determine the structure of Participants will make two vis- of Medicine who earned a medical Staff Distin- Washington, where he was assis- the brain and a positron emission its to the medical center for the degree in 1949 after completing guished Award. tant dean for clinical research tomography scan to analyze amy- testing. Each visit will last two- undergraduate work and two The Shel- and vice chair of the Department loid levels in the brain. Amyloid is and-a-half to three hours. Study years of medical school at the dens received of Anesthesiology. a protein related to memory and volunteers will be compensated University of Missouri-Columbia. the Robert S. His own research interests in- to Alzheimer's disease. for their time. Kharasch was installed as the Brookings clude clinical pharmacology, drug The research team is led by Al- For more information or to Shelden Professor by Chancellor Award at metabolism, drug interactions, ison M. Goate, Ph.D., the Samuel volunteer for the study, call An- Mark S. Wrighton and Larry J. WUSTL's mechanisms of drug toxicity and and Mae S. Ludwig Professor of gela at 362-1558. Shapiro, M.D., executive vice Founder's Day pharmacogenetics, a recent clini- chancellor for medical affairs and last November. Kharasch cal pursuit that focuses on under- dean of the School of Medicine. "I am very standing individual differences in "I thank the Sheldens for their interested in medicine in my responses to drugs. Nominations sought for service award continued generosity to Washing- state," Shelden said. "These endow- "I am privileged and grateful It's time again to nominate nominations for the research sup- ton University," Wrighton said. ments are our attempt to further to receive this honor, and I be- School of Medicine staff for this port and operations staff awards. "Endowments for professorships the progress of medical education lieve it recognizes the entire De- year's Dean's Distinguished Ser- Those awards honor current em- provide key support for our mis- and research both at Washington partment of Anesthesiology; its vice Award, the highest honor ployees who perform duties that sion to recruit and maintain the University and the University of culture of scholarly inquiry and awarded to a medical staff mem- exceed job expectations and outstanding researchers and edu- Missouri-Columbia." education; and our clinicians, sci- ber. The award, which includes a demonstrate outstanding leader- cators who make up our faculty, According to Alex S. Evers, entists and leadership," Kharasch $1,000 cash prize, recognizes a ship and superior quality service. and the Sheldens have been ex- M.D., the Henry Elliot Mallinck- said. "These individuals are re- full-time medical school employ- Each recipient will receive $500. traordinarily generous in helping rodt Professor and head of the sponsible for making this one of ee with at least three years of con- All winners will be recognized make that possible." anesthesiology department, this the very best academic anesthesi- tinuous service, who shows com- during Employee Appreciation "Evan Kharasch is one of the second Shelden Professorship will ology departments in the United mitment to exceeding his or her Week June 4-8. leading physician-scientists in the help support the department's States, and I am proud to be a job responsibilities, creates a posi- For more information, visit field of translational research," efforts to efficiently advance re- member of the team." tive working and learning envi- aladdin.wustl.edu/jobs.nsf or Shapiro said. "Endowed professor- search findings into clinical Kharasch has written more ronment and improves the com- check posters around the medical ships like this one allow us to rec- practice. than 160 scientific articles and a munity. school. All nominations are due ognize outstanding work by indi- "The continued generosity of textbook. The school also is seeking March 31. 4 RECORD WASHINGTON UNIVERSITY IN ST. LOUIS University Events

Political satirist Christopher Buckley Lost Tennessee Williams poem published to speak for Assembly Series Feb. 21 An unknown poem by famed playwright Ten- BY KURT MUELLER plores the plight of baby-boomers and nessee Williams was a for- Blue Song generational warfare. tuitous find for Henry I. Christopher Buckley, novelist, political Widely known for his wit and wry Schvey, Ph.D., professor and I am tired satirist and editor, will present humor, Buckley was a speechwriter for chair of the Performing Arts "Thank You for Smoking: A Conver- Vice President George H.W Bush. Department in Arts & I am tired of speech and of action sation With Christopher Buckley," as the After graduating with honors from Yale Sciences. If you should meet me upon a ArtSci Council/Neureuther Library Lec- University and a stint with the Merchant In 2004 in a bookstore in ture for the Assembly Series. Marines, Buckley became managing editor New Orleans, Schvey found street do not question me for The talk, which is free and open to of Esquire Magazine at age 24. the 17-line poem penciled the public, will take He published his first best-seller, the into the back of a blue exam- I can tell you only my name place at 11 a.m. Feb. 21 travelogue "Steaming to Bamboola: The ination booklet Williams and the name of the town I was in Graham Chapel. World of a Tramp Freighter," five years used for a Greek final as a Buckley, who was later. student at WUSTL in 1937. born in — But that is enough awarded the 2004 In 1989, the late Malcolm Forbes hired "It is clearly the work of a It does not matter whether tomorrow Thurber Prize for Amer- Buckley to start a new magazine, Forbes young man who doesn't ican Humor for his FYI, now known as ForbesLife. It is pub- know his next move in life," arrives anymore. If there is Schvey said of the poem. novel "No Way to Treat lished bi-monthly and is an irreverent only this night and after it is a First Lady," is the au- lifestyle magazine chronicling "The Good Schvey's find also was for- tuitous for Williams' fans, thor of 11 books. His Buckley Life." morning it will not matter now. who otherwise might never acclaimed novel, Besides his satirical novels, travelogues have known of its existence. I am tired. I am tired of speech "Thank You for Smoking," was made into and short stories, Buckley has written for a film by the same name in 2006. Its pro- Titled "Blue Song," the long- and of action. In the heart of me national newspapers and magazines and lost work had never been tagonist is a lobbyist for the tobacco in- has published more than 50 comic essays in published — and possibly dustry. you will find a tiny handful of The New Yorker. never read — until The New Buckley's 1999 book, "Little Green He is the son of William F. Buckley Jr., Yorker magazine ran it in De- dust. Take it and blow it out Men," about a government agency investi- renowned novelist, journalist and com- cember. The blue book now upon the wind. Let the wind have gating UFO sightings, also will be made mentator. is part of the University Li- into a film with a scheduled 2008 release. For more information, call 935-4620 or braries Department of Spe- it and it will find its way home. His upcoming novel, "Boomsday," ex- visit assemblyseries.wustl.edu. cial Collections. 'Take Care of My Caf • Jazz Sahara • Respect for Nature

"University Events" lists a portion of the Storage." Guozhong Cao, materials sci- tecture & Urban Design. Lab. Sciences te physiology, U. of Mich. McDonnell Caucasian Patients with Rheumatoid activities taking place Feb. 15-28 at ence & engineering, U. of Wash. Cupples Bldg., Rm. 300. 935-9300. Medical Sciences Bldg., Rm. 426. Arthritis." Richard Brasington, assoc. Washington University. Visit the Web II Hall, Rm. 100. 936-6540. 362-6950. prof, of medicine. Center for Clinical for expanded calendars for the Danforth Research Training, Conference Rm. 1. Campus (calendar.wustl.edu) and the 4 p.m. Chemistry Seminar. "Electron- Tuesday, Feb. 20 12:30 p.m. Molecular Biology & Pharma- nuclear Interactions in Optically Polarized cology Lecture. Annual Oliver H. Lowry 454-8960. School of Medicine (medschool Noon. Molecular Microbiology & Microbial NMR of GaAs Semiconductors." Sophia Lecture. "Nuclear Cloning, Stem Cells, .wustl.edu/calendars.html). Pathogenesis Seminar Series. "New 4 p.m. Chemistry Seminar. "Towards Hayes, asst. prof, of chemistry. McMHIen Therapy: Promise, Problems, Reality." Insights into Plasmodium Proteolysis." Molecular Electronics: Selective Dep- Lab., Rm. 311. 935-6530. Rudolf Jaenisch, prof, of biology, Mass. Daniel Goldberg, prof, of internal medi- osition of Metals on Patterned Self- Inst. of Technology. Moore Aud., 660 S. 4 p.m. Ophthalmology & Visual Sciences cine. Cori Aud., 4565 McKinley Ave. assembled Monolayer Surfaces." Amy Euclid Ave. 362-0198. Exhibits Seminar. "GFL Neurotrophic Factors: 362-3692. Walker, asst. prof, of chemistry. McMillen Biology, Pharmacology and Clinical 1 p.m. Skandalaris Center Innovators & Lab., Rm. 311.935-6530. Development." Eugene Johnson, prof, of I p.m. K12 Multidisciplinary Clinical Annual Graduate Student Art Exhibit. Research Career Development Program Entrepreneurs Workshop Series. "Exam- 4:15 p.m. Earth & Planetary Sciences molecular biology & pharmacology and of ples of Entrepreneurs" and "Promoting Through Feb. 27. Baseline Workshop, Seminar. Seth Eisen, prof, of medicine. Colloquium. "Microbial Geochemistry at neurology. Maternity Bldg., Rm. 725. Creativity and Innovation." Simon Hall. Showroom and Gallery, 1110 Washington Center for Clinical Research Training, the Edge of the Biosphere: Geocatalysis, 362-3315. For information and to register: Ave.grad.wustl.edu/~gradexhibit/home. Conference Rm. 1. 454-8960. Growth and Diagenesis." Matthew sc.wustl.edu. "Eyes on the Prize: Documenting the Civil 4:15 p.m. Earth & Planetary Sciences Schrenk, NASA postdoctoral fellow, Rights Movement." Through Feb. 28. Olin Colloquium. Larry A. Haskin Memorial 2 p.m. Center for Materials Innovation & Carnegie inst. of Washington. Earth & Library Grand Staircase Lobby. 935-5495. Colloquium. "The Early Differentiation of Wednesday, Feb. 21 Mechanical & Aerospace Engineering Planetary Sciences Bldg., Rm. 203. Terrestrial Planets." Francis Albarede, prof, II a.m. Assembly Series. ArtSci Council/ Joint Seminar. "Mechanical Response of 935-5610. "Reality Bites." Feb. 9-April 29. Kemper Art and chair, dept. des sciences de la vie et Neureuther Library Lecture. "Thank You Pyramidal Truss Core Sandwich Panels." Museum. 935-4523. de la terre, Ecole Normale Superieure, for Smoking: A Conversation with Chri- Hilary Bart-Smith, asst. prof, of mechani- Wednesday, Feb. 28 School of Medicine Student, Faculty & Paris. Earth & Planetary Sciences Bldg., stopher Buckley." Christopher Buckley, cal & aerospace engineering, U. of Va. Staff Art Show '07. Through Feb. 26. Rm. 203. 935-5610. author. Graham Chapel. 935-5285. Lopata Hall, Rm. 101. 936-6540. 4 p.m. Center for the Humanities Lecture. Farrell Learning & Teaching Center, First "Jazz Sahara: The Music of Ahmed Abdul- 5 p.m. Surgery Seminar. Eugene M. Malik." Robin Kelley, prof, of history and Floor Atrium, [email protected] Bricker Visiting Lecture in Surgery. .wustl.edu. Friday, Feb. 16 Saturday, Feb. 24 American studies and ethnicity, U. of "Primary Hyperparathyroidism." Robert 9:15 a.m. Pediatric Grand Rounds. 7:30 a.m.-12:40 p.m. Cardiovascular Southern Calif. (Reception follows.) Music "Selections from the Black Film Promo- Udelsman, prof, and chair of surgery, Yale "Natural Killers Within." Anthony French, Disease CME Course. "9th Annual Classroom Bldg., Rm. 102. 935-5576. tional Materials Collection." Through U. Part of the dept. of surgery "Invitation asst. prof, of pediatrics. Clopton Aud., Update in Cardiovascular Diseases and Feb. 28. Olin Library, Lvl. 1, Ginkgo Day." Eric P. Newman Education Center. 4 p.m. Division of Biology & Biomedical 4950 Children's Place. 454-6006. Hypertension." Cost: $75. Eric P. Newman Reading Rm. 935-5495. For costs and to register: 362-6891. Sciences "Frontiers in Human Patho- 11 a.m. Energy, Environmental & Chem- Education Center. To register: 362-6891. biology" Lecture Series. Dan Goldberg, "Emancipation: A Celebration of Local ical Engineering Seminar. "Addressing 11 a.m. MLA Saturday Seminar. "Respect prof, of medicine. Farrell Learning & Artists with Mental Illness." Opens 7-9 Thursday, Feb. 22 Asthma Care in the Community." Mario for Nature." Claude Evans, assoc. prof, of Teaching Center, Holden Aud. 362-4806. p.m. Feb. 27. Exhibit continues through Castro, assoc. prof, of medicine and of 7:30 a.m.-5 p.m. Surgery CME Course. philosophy. McDonnell Hall, Goldfarb March 9. Sponsored by the Mental Health pediatrics. Lopata Hall, Rm. 101. "15th Annual Refresher Course and Aud. 935-6700. Outreach Project. Farrell Learning & 935-5548. Update in General Surgery." (Continues Teaching Center. 910-1830. 7:30 a.m.-9:30 p.m. Feb. 23, 7:30 a.m.-5 Monday, Feb. 26 Music Saturday, Feb. 17 p.m. Feb. 24.) The Ritz-Carlton, St. Louis, 10 Carondelet Plaza. For costs and to reg- 8 a.m.-5 p.m. St. Louis STD/HIV Preven- 11 a.m. MLA Saturday Seminar. "Agri- ister: 362-6891. tion Training Center Course. "STD In- Thursday, Feb. 15 Film culture and Conservation." Barbara 8 p.m. Jazz at Holmes. William Lenihan, Noon. Genetics Seminar Series. "Function tensive." (Continues 8 a.m.-5 p.m. Feb. Schaal, Spencer T. Olin Professor of guitar. Ridgley Hall, Holmes Lounge. and Evolution of Human Cis-regulatory 27-28.) Cost: $125. For location and to Biology. McDonnell Hall, Goldfarb Aud. register: 747-1522. 935-4841. Friday, Feb. 16 935-6700. Sequences: From Extreme Conservation to 7 p.m. Korean Film Festival: The Varied Adaptive Divergence." Shyam Prabhakar, 2:30 p.m. Energy, Environmental and Colors of Korean Cinema. "Joint Security genomics div., Lawrence Berkeley Na- Chemical Engineering Seminar. Nitin Sunday, Feb. 18 Monday, Feb. 19 tional Lab., Calif. McDonnell Medical Area" (2000). Pak Chanwook, dir. Brown Baliga, asst. prof, of systems biology, 6 p.m. Voice recital. Tasha Nicholson. Sciences Bldg., Rm. 823. 362-2139. Hall, Rm. 100. 935-4448. 2:30 p.m. Energy, Environmental & Chem- U. of Wash. Lopata Hall, Rm. 101. Whitaker Hall Aud. 935-4841. 935-5548. ical Engineering Seminar. "Renewable 4 p.m. Ophthalmology & Visual Sciences Friday, Feb. 23 Energy Solutions." John Turner, National Seminar. "GFL Neurotrophic Factors: 4 p.m. Immunology Research Seminar Renewable Energy Lab. Lopata Hall, Biology, Pharmacology and Clinical Series. "Not Enough Regulation in Innate 7 p.m. Korean Film Festival: The Varied Rm. 101.935-5548. Development." Eugene Johnson, prof, of Immunity." John Atkinson, Samuel Grant Colors of Korean Cinema. "Take Care of On stage molecular biology & pharmacology. Professor of Medicine. Farrell Learning & My Cat" (2001). Jeong Jaeeun, dir. Brown 4 p.m. Immunology Research Seminar Maternity Bldg., Rm. 725. 362-3315. Teaching Center, Connor Aud. 362-2763. Hall, Rm. 100. 935-4448. Series. "Inflammation and Immunity Friday, Feb. 16 Intersect at XPB-1." Laurie Glimcher, Irene 4:15 p.m. Earth & Planetary Sciences 5:30 p.m. Cardiac Bioelectricity and Heinz Given Professor of Immunology, Colloquium. "Who Constructed the Oldest Arrhythmia Center Seminar Series. 8 p.m. OVATIONS! Series. "1984." The Wednesday, Feb. 28 Harvard U. Farrell Learning & Teaching Fossilized Microbial Mats?" Michael Tice, "Inflammatory Pathways as Targets for Actors' Gang. In conjunction with The Big 7 p.m. Japanese Film Series. "Black Rain" Center, Connor Aud. 362-2763. postdoctoral scholar, geological & plane- the Treatment and Prevention of Atrial Read. (Also 8 p.m. Feb. 17.) Cost: $30, $25 for seniors, WUSTL faculty & staff; (1989). Shohei Imamura, dir. Sponsored 4 p.m. Physics & Center for Materials tary science, Calif. Inst. of Technology. Fibrillation." David Van Wagoner, assoc. $18 for students and children. Edison by Asian & Near Eastern Languages & Innovation Joint Seminar. "First Prin- Earth & Planetary Sciences Bldg., prof, of molecular medicine, Case Wes- Theatre. 935-6543. Literatures. Busch Hall, Rm. 100. ciples Investigation of Magnetic Ferro- Rm. 203. 935-5610. tern Reserve U. (5 p.m. reception.) 935-5110. electrics." Claude Ederer, dept. of physics, Whitaker Hall, Rm. 218. 935-7887. Columbia U. (3:30 p.m. coffee, Compton Friday, Feb. 23 Friday, Feb. 23 Hall, Rm. 245.) Crow Hall, Rm. 201. Tuesday, Feb. 27 8 p.m. OVATIONS! Series. DanceBrazil. Co- 935-6276. 9:15 a.m. Pediatric Grand Rounds. "When Lectures Does No Mean No? Assent and Dissent in Noon. Molecular Microbiology & Micro- presented by Dance St. Louis. (Also 8 5:30 p.m. Cardiac Bioelectricity & Arrhy- Pediatric Research." Rebecca Dresser, bial Pathogenesis Seminar Series. p.m. Feb. 24; 2 p.m. Feb. 25.) Cost: $30, thmia Center Seminar Series. "Control Daniel Noyes Kirby Professor of Law. "Pathobiology of Prion Diseases: Loss, $25 for seniors, WUSTL faculty & staff; Thursday, Feb. 15 of Normal Rate and Rhythm by a Widely Clopton Aud., 4950 Children's Place. Gain, of Subversion of Function?" David $18 for students and children. Edison Theatre. 935-6543. Noon. Genetics Seminar Series. "The Distributed, Functionally Differentiated and 454-6006. Harris, prof, of cell biology & physiology. BRCA1-BRCA2 Pathway of DNA Repair in Integrated System of Atrial Pacemakers: Cori Aud. 4565 McKinley Ave. 747-2132. 8 p.m. Performing Arts Dept. Presen- The Pacemaker Complex." John Boineau, 11 a.m. Energy, Environmental and Chem- Human Cancers." Simon Powell, prof, of ical Engineering Seminar Series. Glenn Noon. Program in Physical Therapy tation, "civil disobedience" by Carter radiation oncology. McDonnell Medical prof, of surgery, medicine and biomedical Lewis. Andrea Urice, dir. (Also 8 p.m. Feb. engineering. (5 p.m. reception.) Whitaker Waychunas, Lawrence Berkeley National Research Seminar. 4444 Forest Park Sciences Bldg., Rm. 823. 362-2139. Lab., Calif. Lopata Hall, Rm. 101. Blvd., Lower Lvl., Rm. B108. 286-1404. 24, March 2 & 3; 2 p.m. Feb. 25 & March Hall, Rm. 218. 935-7887. 4.) Cost: $15, $9 for students, children, 2:30 p.m. Center for Materials Innovation 935-5548. 1 p.m. K12 Multidisciplinary Clinical seniors, WUSTL faculty & staff. Mallinc- & Mechanical & Aerospace Engineering 6:30 p.m. Sam Fox School Architecture Lecture Series. "Collective Practice." Noon. Cell Biology & Physiology Seminar. Research Career Development Program krodt Student Center, A.E. Hotchner Joint Seminar. "Nanostructured Materials "Emerging New Roles of Potassium Seminar. "A Pilot Study to Determine Studio Theatre. 935-6543. for Efficient Energy Harvesting and Bruce Lindsey, dean, College of Archi- tecture and Graduate School of Archi- Channels in Cardiac Function." Anatoli Whether Disability and Disease Activity Lipatin, asst. prof, of molecular & integra- are Different in African-American and u record.wustl.edu WASHINGTON UNIVERSITY IN ST. LOUIS Feb. 15,2007 5

Orwell's '1984' comes to life through Law school 'Access to Justice' The Actors' Gang at Edison Theatre speaker series continues Feb. 21

BY LIAM OTTEN BY JESSICA MARTIN contract law incorporate and influence social norms. Imagine a world where people The New York Times' Su- Davis is the Webster Society cannot speak freely, where lead- preme Court correspondent Annual Speaker and a University ers are not held accountable, is part of the spring lineup for Distinguished Visiting Scholar. where constant war rages against the School of Law's ninth an- • 4 p.m. March 7: Linda an unseen enemy. nual Public Interest Law and Greenhouse, Supreme Court Welcome to "1984," George Policy Speakers Series. correspondent for The New Orwell's prescient portrait of an Titled "Access to Justice: York Times, will speak on "The oppressive, totalitarian society. In The Social Responsibility of New Supreme Court: Continu- February, The Actors' Gang — an Lawyers," the series brings to ity and Change." experimental Los Angeles troupe WTJSTL outstanding academics Greenhouse, the annual led by artistic director and Acade- and practitioners in areas such School of Law Tyrrell Williams my Award-winner Tim Robbins as international human rights, Lecturer, began covering the — will present a new stage adap- the economics of poverty, civil Supreme Court for the Times in tation of Orwell's dystopic classic liberties, racial justice, capital 1978. She has served in that role at Edison Theatre. punishment, clinical legal edu- ever since, except for two years Performances, sponsored as cation, and government and in the mid-1980s when she cov- private public service. ered the U.S. Congress. part of the Edison Theatre OVA- (From left) Brian T. Finney, Brent Hinkley and Kaili Hollister of The The goals of the series are to Previously, she covered local TIONS! Series, begin at 8 p.m. Actors' Gang, led by artistic director Tim Robbins, perform in a new Feb. 16-17. stage adaptation of George Orwell's "1984" Feb. 16-17. provide a forum for the law and state government and poli- "1984" tells the story of Win- school and the wider Universi- tics for the Times in New York ston Smith (played by Brent ty community to engage in a and was chief of the newspaper's Hinkley), a London functionary San Francisco. cause of the danger they perceive discussion of the legal, social legislative bureau in Albany. She for the government of Oceana, "I was so excited by his fram- that they are in. and ethical issues that bear has appeared as a panelist on one of three sprawling regimes ing of the story, his ability to "Big Brother rules through upon access to justice; to high- the PBS public affairs program that dominate the globe. make the material resonate," Rob- fear," Robbins concluded. "Big light the professional responsi- "Washington Week" since 1980. Though Winston works for bins said. Brother provides no vision of the bilities of law students and • 11 a.m. March 28: Robert the tyrannical Ministry of Truth, He also was "floored by its rel- future other than a promise of ul- lawyers to provide access to A. Williams Jr., J.D., the E. he secretly flirts with independent evance, its insight, its warnings, timate victory and perpetual war." justice; and to promote schol- Thomas Sullivan Professor of thinking. and unfortunately realized that Robbins co-founded The Ac- arship in this area. Law and American Indian Stud- Even more dangerously, he this book was more vibrant and tors' Gang in 1982. The company The spring series kicked off ies and director of the Indige- falls in love with the rebellious, necessary now than it had ever is dedicated to creating bold, Jan. 17 with a lecture by Sherri- nous Peoples Law and Policy promiscuous Julia (played by been," he said. original and socially relevant lyn Ifill, J.D., titled "Twenty- Program at the University of Kaili Hollister). Yet the couple's "What Orwell is talking about works for the stage, as well as first Century Challenges to Arizona, will present "Like a brief affair is soon uncovered and is totalitarianism of the mind, daring reinterpretations of classic Racial Justice Lawyering." Ifill, Loaded Weapon: The Rehnquist both are sent to the Ministry of where free will and free thought is works. associate professor at the Uni- Court, Indian Rights and the Love for "reprogramming." viewed as a threat to the overall Tickets are $30; $25 for sen- versity of Maryland School of Legal History of Racism in The Actors' Gang production safety of the state," Robbins added. iors, faculty and staff; and $18 for Law, was the Black Law Stu- America." is directed by Robbins and based "The citizens of all nation-states students and children. dents Association Martin Lu- Williams, a University Dis- on a script by Michael Gene Sulli- readily comply with the wishes of For more information, call ther King Jr. Commemorative tinguished Visiting Professor, is van, head writer for the Tony the state, however compromising 935-6543 or visit edisontheatre Speaker. the author of several books and Award-winning Mime Troupe in it is to their personal freedom, be- .wustl.edu. The remaining presenta- articles on federal Indian law tions, listed below, will be held and indigenous peoples' human in the Bryan Cave Moot Court- rights. Who says engineers room of Anheuser-Busch Hall An enrolled member of the 'Collective Practice' topic of Lindsey's and are free and open to the Lumbee Indian Tribe of North don't have fun? public. Carolina, he is the judge pro talk for Architecture Lecture Series • 11 a.m. Feb. 21: Adrienne tempore for the Tohono O'od- Crazy chemistry demonstra- Davis, J.D., the Reef C. Ivey II ham Indian Nation. Architect Bruce Lindsey — ing which time he helped unite tions, a paper airplane compe- Professor of Law at the Univer- Series coordinators are Karen who joined the Sam Fox the school's five degree pro- tition and sticking a person to a sity of North Carolina, will dis- L. Tokarz, J.D., LL.M., professor School of Design & Visual Arts grams — comprising 600 stu- wall with duct tape are part of the cuss "Reparations as Transi- of law and executive director of last fall as dean of the College of dents and 40 faculty — through campus events planned for En- tional Justice." clinical education and alterna- Architecture and the Graduate a series of interdisciplinary and Week 2007, celebrating National Davis focuses her scholar- tive dispute resolution pro- School of Architecture 8c Urban joint-degree offerings. Engineers Week, Feb. 18-24. ship on the interplay of proper- grams, and Peter J. Wiedenbeck, Design — will speak about his Lindsey's research long has EnCouncil, the undergraduate ty and contract doctrine with J.D., associate dean of faculty work at 6:30 p.m. Feb. 19 as part focused on applying digital tools student government for the race, gender and sexuality in and the Joseph H. Zumbalen of the spring Architecture to design and construction prac- School of Engineering 8c Applied the 19th century. Professor of the Law of Pro- Lecture Series. tice. In 1992, his work in digital- Science, is hosting the free activi- Drawing on legal, literary perty. The talk, titled "Collective aided manufacturing was cited ties. and historical sources, Davis' For more information, call Practice," is free and open to the by Engineering News Record as On Feb. 19, crazy chemistry work shows how property and 935-6419. public and takes place in Brown one of the year's 10 most signifi- demonstrations will take place Hall, Room 118. cant contributions to the con- from 11 a.m.-l p.m. in Bowles A native of Idaho, Lindsey struction industry. Plaza. earned a bachelor's degree in art A practicing architect, Lind- If you can make a paper air- Community Powwow Meeting Feb. 19 in 1976 and a master's degree in sey recently worked with Davis plane that flies across the gallery Individuals interested in being a festival of American Indian sculpture and photography in + Gannon Architects to design in Lopata Hall between 11 a.m.- I part of the 17th annual pow- dancing, singing, drumming, arts, 1979, both from the University the Pittsburgh Glass Center, I p.m. Feb. 21, you could win a I wow at WUSTL are invited to crafts and food. They also will of Utah. which earned a gold rating prize. attend the Community Powwow discuss event volunteer opportu- He earned a master's degree under the U.S. Green Building Find out how many rolls of Meeting from 5:30-8 p.m. Feb. 19 nities. The powwow is scheduled in architecture from Yale Univer- Council's Leadership in Envi- duct tape it takes to stick some- in Goldfarb Hall, Room 124. for April 14. sity in 1986 and joined the facul- ronmental 8c Energy Design one to a wall from 11 a.m.-l p.m. The staff and students of the A light dinner will be provid- ty at Carnegie Mellon University guidelines. Feb. 21 in the gallery of Lopata Kathryn M. Buder Center for ed during the meeting. Those in- the following year. The project also received a Hall. American Indian Studies at the terested in attending should From 1994-2001, he served as Design Honor Award from the During the week, the public George Warren Brown School of R.S.V.P. by calling 935-4510 or by associate head of Carnegie Mel- American Institute of Architects also can: Social Work are looking for com- sending an e-mail to bcais@ Ion's School of Architecture and (AIA) and was chosen as one of • Join the weeklong "Golden munity input about the powwow, gwbmail.wustl.edu. as associate professor of art and 2005's Top 10 green buildings by Mouse Hunt," with clues leading architecture. the AIA's Committee on the En- to places throughout the engineer- Lindsey served as head of vironment. ing school, beginning Feb. 19. Auburn University's School of For more information, call • Add stickers and rhinestones Architecture from 2001-06, dur- 935-9300 or visit arch.wustl.edu. to your calculator at the "Pimp Your Calculator" event from II a.m.-l p.m. Feb. 19 in Mallinc- Volume 31, Number 22 krodt Student Center. Sports And more • Watch students take on engi- Founded in 1905 neering school faculty in basket- Washington University community news Saturday, Feb. 24 Thursday, Feb. 15 ball and dodgeball from 7-9 p.m. Associate Vice Chancellor Steven J. Givens Record (USPS 600-430; ISSN 1043-0520), Executive Editor Susan Killenberg McGinn Published for the faculty, staff and friends 1 p.m. Women's basketball vs. U. of 5 p.m. Skandalaris Center IdeaBounce Feb. 19 at the Athletic Complex. Chicago. Athletic Complex. 935-4705. Event. Simon Hall, May Aud. 935-7668. • See the construction of a Editor Martha M. Everett of Washington University. Produced weekly Associate Editor Andy Clendennen during the school year, except school 3 p.m. Men's basketball vs. U. of swing from Styrofoam and pack- Associate Editor Neil Schoenherr holidays, and monthly during June, July Chicago. Athletic Complex. 935-4705. Friday, Feb. 16 ing tape — and maybe an engi- Medical News Editor Beth Miller and August by the Office of Public Affairs, 6:30 p.m. The Big Read Event. Theatrical neering dean swinging in it — Calendar Coordinator Genevieve Posey Washington University, Campus Box 1070, readings from "Fahrenheit 451" and from 11 a.m.-l p.m. Feb. 20 in Print Production Carl Jacobs One Brookings Drive, St. Louis, M0 63130. docent-led tours of "Reality Bites." Bowles Plaza. Online Production Genevieve Posey Periodicals postage paid at St. Louis, M0. Worship Kemper Art Museum. 935-4523. • Watch a tricycle race around News & Comments Where to send address changes the Ann W. Olin Women's Build- (314)935-6603 Postmaster and nonemployees: Record, Wednesday, Feb. 21 Sunday, Feb. 18 Campus Box 1070 ing from 11 a.m.-l p.m. Feb. 23. Washington University, Campus Box 1070, 12:05 Ash Wednesday Catholic Mass. St. 2 p.m. Reading and Book Discussion. [email protected] Louis College of Pharmacy, Whelpley • Bid on a date with a man or One Brookings Drive, St. Louis, M0 63130. "Fahrenheit 451." Part of The Big Read. woman from the engineering Medical News Hall, [email protected]. Kemper Art Museum. 935-4407. Employees: Office of Human Resources, school at the "Date Auction" from (314)286-0119 Washington University, Campus Box 1184, 12:15 p.m. Ash Wednesday Ecumenical Campus Box 8508 9-11 p.m. Feb. 23 at The Gar- One Brookings Drive, St. Louis, M0 63130. Ashes Service. Catholic Student Cen- Friday, Feb. 23 [email protected] ter, 6352 Forsyth Blvd. modde® goyle. Proceeds from the event Calendar Submissions Reprint permission washucsc.org. 4:30 p.m. Memorial Service. In honor of benefit the American Cancer So- Irene E. and Michael M. Karl. Farrell Fax: (314) 935-4259 Articles may be reprinted with appropriate 5:15 p.m. Ash Wednesday Catholic Mass. Learning & Teaching Center, Connor Aud. ciety. Campus Box 1070 credit to Washington University in St. Louis Catholic Student Center, 6352 Forsyth (Reception follows.) R.S.V.P. to 286-0073. For more information, visit [email protected] Record. Blvd. [email protected]. enweek.net. 6 RECORD WASHINGTON UNIVERSITY IN ST. LOUIS Sports

Junior Srikanth named Bears with a career-high 27 points Men's, women's track and nine assists; he scored 23 of diver of the year his points in the second half. and field shine The women's swimming and div- The men's and women's track and ing team placed third and the men Women's basketball field teams turned in impressive took fourth at the 2007 UAA performances Feb. 10 at the Illinois Championships Feb. 8-10 in wins pair of UAA games College Blue Classic in Jackson- Cleveland. The women's basketball team (17- ville, 111., each taking second. The women totaled 10 event ti- 5, 9-2 UAA) picked up two critical Senior Beth Herndon won the tles in three days and were paced home conference wins last week- 5,000-meter run; classmate Natal- by junior Meredith Nordbrock, end at the WUSTL Field House. ie Badowski took first place in the who posted three individual titles The Red and Green defeated 400 meters (59.72); and sopho- and helped Bears relay squads win Emory, 62-50, Feb. 9 behind sen- more Alii Alberts did the same in three additional events. She swept ior Sarah Schell's game-high 19 the 800 (2:22.20). In the field and 200-yard and 400-yard indi- points. events, sophomore Jessica Lane vidual medleys and the 200-yard Freshman Janice Evans added a won the pole vault and senior De- backstroke; and she swam the sec- career-best 13 points. laina Martin improved her NCAA ond leg of the winning 400- and On Feb. 11, WUSTL upended provisional mark in the weight Erik Herzog, Ph.D., monitors graphs on a computer that represent Case Western Reserve, 67-56, as the electrical firing of neurons in mice brains activated by the odor 800-freestyle relays, while she led throw (15.75m, 51-8). Schell led the way again. She stimulus cedar oil. The research showed that the neurons are ac- off the winning 200-medley relay For the men, freshman Iby tive for several hours at about the same time each day and helped squad. scored 15 of her 18 points in the Umana and sophomore Nate lead to the conclusion that mice have a biological clock for smell. Junior Priya Srikanth garnered second half and hit 16 of 20 free Koslof finished second and third, Women's Diver of the Year honors throws; she added two blocked respectively, in the 400 meters. by sweeping the one-meter and shots and five steals. Senior Re- Umana posted a team-season-best literature about humans liking three-meter diving titles becca Parker added 17 points and time of 51.02 and Koslof finished certain perfumes more during the On the men's side, freshman nine rebounds. in 51.16. Clocks evening than the morning, and Alex Beyer won the 400-yard IM Studying olfactory there is some evidence that we also in 4:03.05 for an NCAA provision- behavior to follow have daily rhythms in olfaction," al mark; he also swam the second their hard work was evident in - from Page 1 Herzog said. leg of the 800-free relay, which their performance. What makes Herzog's next step is to study won the UAA title in 6:49.75. For Students their performance and prepara- the olfactory behavior of mice. his efforts, Beyer was named the La w school convn unity tion even more impressive is They saw more of those cells "We'll ask the mice to tell us Men's Rookie of the Year. when you consider that they are light up — thanks to a biolumi- when they can smell odors of dif- lends valued support also taking a full course load and nescence marker associated with ferent concentrations, and we Men's basketball - from Page 1 one or more of the students ac- cFOS — in the olfactory bulb at hope to learn more about how and bounces back tively participate on other moot night than in the day. how much the clock modulates court teams and competitions, "The olfactory bulb might be their sense of smell and which Junior Troy Ruths scored a team- Prior to announcing the win- the trial team and are editors and more sensitive at night when the cells and genes are needed," he high 16 points and grabbed nine ners of the competition, Roberts staff members of law journals." creatures are active than when said. rebounds as the No. 11 men's bas- presented second-year student Frazier and Rhoads were im- they are resting in the day," Her- A key question raised by the ol- ketball team defeated visiting Case Toneille Raglan with the Golden pressed by the encouragement zog speculated. "This might help factory bulb biological clock study Western Reserve, 86-65, Feb. 11 in Gavel Award, which is given to from the law school community. them find food or mates when is why multiple clocks exist. UAA action. Senior Nick Nikitas the best oral advocate in the pre- "The most amazing thing they are hungry for food or for "This idea of multiple biological and sophomore Sean Wallis each liminary rounds. about preparing for and partici- love." clocks is new," Herzog said. "We chipped in 13 points for the Bears, He also named Derick Albers pating in the finals was the good- Do the results suggest humans might need now to consider our- who improved to 18-3, and 9-2 in and Bryan Boyle, both second- ness that we saw in people before, should wear perfume or cologne selves a clock shop. It appears that the UAA. year students, winners of the during and after the argument," at night and shun the bottle dur- disrupting the coordination be- On Feb. 9, the Bears defeated Golden Quill Award, which is Rhoads said. "There are some real- ing the day? tween these clocks is bad for our Emory University, 74-62, at the presented for the best legal brief. ly great people in the law school, "There are anecdotes in the health, like in jet lag or shift work." Field House. Wallis paced the "The student litigants were and the sharing of good will was outstanding," said Jo Ellen Lewis, in a way as rewarding as the honor J.D., director of the legal practice of arguing before the chief justice." everything. Its name is taken think that they may be able to program and senior lecturer in Frazier agreed. "I've been from the Latin word meaning help people with diabetes and hy- law, who served as faculty adviser overwhelmed by the kindness and Nerve "wanderer." pertension by interrupting nor- • for the competition along with genuine moral support of the Interrupting brain Early neuroanatomists chose mal vagal signaling. Bill Dorothy, J.D., senior lecturer other students, the faculty and the name because it seemed And there may be a ready- in law. "They worked very hard to the dean," he said. "I hope we signals is study key whenever they looked at an organ made population to study because prepare for the competition, and made them proud." - from Page 1 in the body, they also found fibers many people already have surgi- from the vagus. cally implanted devices that alter It extends from the base of the the signaling of the vagus nerve. initiatives at WUSTL. a novel approach for treating brain through the chest, where it Some people with seizure dis- Cox and his wife, Barbara, es- these common metabolic disor- innervates part of the heart. It ■ orders and treatment-resistant de- Turner tablished the professorship Turner ders." also sends nerve signals to other pression have implanted elec- Honor adds to engineer's holds. Previously, the research team internal organs, including the trodes that stimulate the vagus Turner has been awarded 30 had shown that a nuclear recep- liver, and eventually connects to nerve to help alleviate their symp- distinguished career patents for his work on switching tor called PPAR-alpha (Ppara) the intestine. toms. - from Page 1 systems. was necessary for the induction In these studies, however, the Semenkovich said he believes Turner was one of WUSTL's of both diabetes and hyperten- researchers were interested mainly the new mouse study suggests a first dual-degree graduates, earn- sion when mice were treated with in the connection between the similar approach might help peo- profession and to the University," ing bachelor's degrees in comput- glucocorticoids, also known as vagus nerve coming from the liver ple with insulin resistance or hy- said Mary J. Sansalone, Ph.D., er science and electrical engineer- steroids. and its communication with the pertension. They plan to follow dean of the engineering school. ing, as well as a bachelor's degree "Mice that can't make Ppara brain. patients who already have stimu- Founded in 1964, the NAE is a from Oberlin College in 1977. don't develop diabetes or hyper- When mice are treated with lators to see if signals from the private, independent, nonprofit Continuing his education at tension in response to glucocorti- glucocorticoids, Ppara in the liver stimulators affect susceptibility to institution that provides engineer- Northwestern University, Turner coids," said Semenkovich, who communicates with the vagus diabetes, insulin resistance or hy- ing leadership in service to the na- earned master's and doctoral de- also is chief of the Division of nerve, which signals the brain. pertension. tion. grees in computer science in 1979 Endocrinology, Metabolism and Then the brain uses the vagal "We used surgery to interrupt The NAE advises the federal and 1982, respectively. Lipid Research. pathway to feed back instructions all signaling from the vagal nerve government and conducts inde- During his graduate studies, "The use of steroids is very to the liver and kidneys. The brain pathway," Bernal-Mizrachi said. pendent studies to examine im- Turner worked at AT&T Bell Lab- common in medicine," he added. instructs the liver to increase glu- "But it might actually be possible portant topics in engineering and oratories in Naperville, 111. After "People with asthma, arthritis, cose production and the kidney to to change very specific signaling technology. The NAE is a member leaving Bell Laboratories in 1983, organ transplants and others rely alter fluid metabolism, elevating patterns to provide benefit to of the National Academies, which Turner returned to WUSTL as an on those steroid drugs, and many blood pressure. people who are at risk for hyper- also includes the National Acade- assistant professor of computer of them go on to develop insulin The same sort of process can tension or diabetes." my of Sciences, the Institute of science. In 1990, he became a full resistance that can advance to di- occur in people who are obese. Some available drugs might Medicine and the National Re- professor and later served as de- abetes and hypertension." Semenkovich said a modest eleva- be able to attack the problem in search Council. partment chair from 1992-97. But in these most recent ex- tion of glucocorticoids is associat- other ways. A class of medications In 1998, Turner — with col- Election to the NAE is one of periments, the researchers ed with obesity. Those elevated called fibrate drugs can modulate leagues Jerome R. Cox, Sc.D., sen- many honors and awards Turner showed that both Ppara and the levels can initiate Ppara activity in the activity of Ppara. Those drugs ior professor in computer science has received. He has been ac- vagus nerve seem to play impor- the liver, which then will commu- are used to lower triglycerides and and engineering, and Guru M. knowledged for his technical con- tant roles in the development of nicate with the vagus nerve to sig- to elevate levels of HDL (good) Parulkar, Ph.D., former computer tributions at the highest levels in these disorders. nal the brain, and, in turn, the cholesterol. science and engineering professor the nation, including as the recip- "If the vagus nerve has been brain will signal the liver and kid- Some studies have indicated — founded the WUSTL Applied ient of the Koji Kobayashi Award surgically removed, the mice neys, contributing to diabetes and the drugs provide a modest bene- Research Laboratory. The laborato- in Computers and Communica- won't develop diabetes or hyper- hypertension. fit, but other studies have sug- ry developed a series of high-per- tions and the Institute of Electri- tension in response to glucocorti- "We think obesity is probably gested that such drugs might be formance networking systems and cal and Electronics Engineers' coids, even if they have Ppara," initiating a similar process to the harmful. So for now, the research- technologies, including an early (IEEE) Millennium Medal. said first author Carlos Bernal- one we've interrupted in the ers are focusing more on the po- metropolitan area testbed using Turner has been elected a fel- Mizrachi, M.D., assistant profes- mice," Semenkovich said. tential of the vagus nerve. Asynchronous Transfer Mode low of the Association for Com- sor of medicine in the endo- "An environmental influence "I would argue that you can switches that Turner designed. puting Machinery, as well as the crinology, metabolism and lipid — such as treatment with gluco- clearly produce a major impact by Continuing their collabora- IEEE. He has received numerous research division. corticoids or excess caloric intake stimulating this nerve because it tion, Turner, Cox and Parulkar WUSTL honors, including the "The process seems to be me- that causes obesity — engenders a carries signals to so many organs," founded the start-up company 1993 Distinguished Faculty Award diated by communication be- signal started by Ppara, which Semenkovich said. "We know the Growth Networks, which devel- and the 2004 Arthur Holly Comp- tween the liver cells, the liver then is transmitted from the liver vagal pathway can influence oped high-performance switch- ton Award for Faculty Achieve- branch of the vagus nerve and its along the vagus nerve." seizures, depression and other ing components for Internet ment. This spring, he will receive signals to the brain," he said. That cascade of communica- disorders. This study suggests it routers, and was acquired by the Distinguished Alumni Actually, the vagus nerve tion along the vagal nerve path- affects diabetes and hypertension, Cisco Systems in 2000, becoming Achievement Award from the en- communicates with just about way has made the investigators too." a model for technology-transfer gineering school. record.wustl.edu WASHINGTON UNIVERSITY IN ST. LOUIS Feb. 15,2007 7 Notables

Introducing new Science academy names nine faculty as fellows faculty members BY TONY FITZPATRICK krodt Professor, head of the Department of Distinguished Professor of Pediatrics, for Anesthesiology and professor of medicine and achievement in medicine; Nine University faculty members were in- of molecular biology and pharmacology, for Raymond Arvidson, Ph.D., the James S. The following are among the ducted along with 17 other scientists and achievement in medicine; Timothy J. Ley, M.D., McDonnell Distinguished University Profes- new faculty members at engineers as Fellows of the Academy of associate director for basic science at Siteman sor, chair of earth and planetary sciences in the University. Others will be Science of St. Louis Ian. 22 in a ceremony at Cancer Center and professor of genetics, for Arts 8c Sciences and co-principal investigator introduced periodically in this the Donald Danforth Plant Science Center. medicine in the area of stem cell biology; of the Mars Exploration Rover Mission, for space. Fellows attain their status by virtue of se- Kenneth S. Polonsky, M.D. the Adolphus achievement in earth and planetary science for lection as members of the National Acade- Busch Professor of Medicine, chair of the Mil- Werner Ploberger, Ph.D., international achievement in planetary science mies, Outstanding St. Louis Scientist Awards liken Department of Internal Medicine, pro- remote sensing; joins the department of eco- given by the academy or as part of a rigorous fessor of cell biology and physiology and Graham Colditz, M.D., Dr.P.H, the Niess- nomics in Arts & Sciences as nomination by the Academy's Board of physician-in-chief at Barnes-Jewish Hospital, Gain Professor in Medicine and associate di- professor. Trustees. for achievement in medicine; Yoram Rudy, rector of Prevention and Control at Siteman He earned a doctorate in The 150-year-old mission of the Academy Ph.D., director of the Cardiac Bioelectricity Cancer Center, for groundbreaking research applied mathematics at Vi- of Science of St. Louis is to "foster the ad- and Arrhythmia Center, the Fred Saigh Distin- on lifestyle impact on chronic disease preven- enna University of Technolo- vancement of science and encouragement of guished Professor of Engineering and profes- tion and treatment; and gy (Austria) in 1981 and a public interest in and understanding of the sor of cell biology and physiology, of medi- Timothy Eberlein, M.D., the Bixby Profes- Habilitation in Econometrics sciences." cine, of radiology and of pediatrics, for sor of Surgery, chair of the Department of there in 1993. The University inductees are Ramanath achievement in biomedical engineering; Surgery, surgeon-in-chief at Barnes-Jewish He has been affiliated Cowsik, Ph.D., professor of physics in Arts & Larry J. Shapiro, M.D., executive vice chan- Hospital and director of Siteman Cancer Cen- with Vienna University of Sciences, for achievement in astroparticle phy- cellor for medical affairs, dean of the School of ter, for leadership in fostering medical ad- Technology, the University of sics; Alex Evers, M.D., the Henry Eliot Mallinc- Medicine and the Spencer T. and Ann W. Olin vances in cancer diagnosis and treatment. St. Andrews (Scotland) and the University of Rochester. He was tenured in 1993 (Vienna) and promoted to 'Rice gone bad': Plant full professor in 1995 (Uni- versity of St. Andrews). He has been at the Uni- biologist investigates versity of Rochester since 1997. BY TONY FITZPATRICK "In this scenario, you have a His research focus is in sort of selection favoring the the areas of statistics, econo- Red rice sounds like a New weedy version of the crop that metric methodology and Orleans dish or a San Fran- out-competes the crop itself," he cisco treat. But it's a weed, the said. "That's called de-domestica- time-series econometrics. biggest nuisance to American tion." Stephen Williamson, Ph.D., rice growers, who are the Another possibility, which is joins the department of eco- fourth-largest exporters of rice not mutually exclusive, is that in the world. And rice farmers weedy rice was introduced into nomics in Arts & Sciences as hate the pest, which, if harvested the Americas from Asia, where professor. along with domesticated rice, weedy hybrids of the cultivated He earned a doctorate reduces marketability and con- species and the wild species from the University of Wis- taminates seed occur. consin in 1984 and has since stocks. These weedy been affiliated with Queen's, Complicat- strains then took Western Ontario, the Federal ing matters is hold in U.S. soils Reserve Bank of Minneapo- the fact that "We are looking for and began con- lis and the University of red rice and taminating the Iowa. cultivated rice candidate genes that U.S. cultivated He was tenured in 1989 are exactly the underlie particular traits species. (Western Ontario) and pro- same species, Olsen said moted to full professor in so an herbicide that differ between the that the weed 1992 (Iowa). cannot be de- two. Knowing more has many char- He served as department veloped that about the traits could acteristics of a chair at Iowa (2000-03). seeks out only wild species. red rice — it "By looking He is co-editor for Eco- help in potentially con- would kill cul- at candidate nomic Theory and associate tivated rice, trolling the weed. We genes and those editor for lournal of Mone- too. have a key advantage genes surround- tary Economics and Review But now a ing them," Olsen of Economic Dynamics. University in this research in that said, "we can test His research is mainly on plant evolu- we know the complete the hypotheses macroeconomics, monetary tionary biolo- of the origins of economics and financial eco- gist has re- cultivated rice genome, traits and see if nomics. ceived a two- so it's fairly easy to target the traits have year, $1.12 been introduced Jimin Ding, Ph.D., joins the million grant genes of interest." by hybridization department of mathematics from the Na- KENNETH M. OLSEN of weedy and in Arts 8c Sciences as assis- tional Science wild species, or, tant professor. LUItChtime leCtlire Michael Frachetti, Ph.D., assistant pro- Foundation conversely, we Ding earned a doctorate fessor of anthropology in Arts & Sciences, speaks on "Deco- (NSF) to per- can look at the in statistics from the Univer- ding Eurasian Nomadic Networks: Integrating Social and Sci- form genetic studies on red rice. molecular level to see if the de- sity of California, Davis, entific Approaches" at the lunch session of the Metropolitan The studies will help under- domestication phenomenon is under the guidance of lane- St. Louis Grants Conference Jan. 10 in Whitaker Hall. The jointly stand molecular differences be- going on." Ling Wang. hosted conference brought together the University and Southern tween the two that someday To control red rice infesta- She works in a modern Illinois University Edwardsville for updates on the latest funding could provide the basis for a tions, growers often rotate crops trends from federal agencies and informative sessions for aca- plan to eradicate the weed. away from rice to soybeans, for form of survival analysis demic researchers on research policies, practices and opportu- The particular NSF program instance. using techniques that will be nities. Attendees also explored ways to enhance the success of funding the research is the Plant And there are cultivation tech- applicable to many other their individual and collaborative research projects. WUSTL Genome Comparative Sequenc- niques that can eliminate most areas of statistics. hosted the first day's program. ing Program. of the threat, although another Kenneth M. Olsen, Ph.D., as- nasty feature of the weed is its XiangTang, Ph.D., joins the sistant professor of biology in dormancy — its seed can lie department of mathematics Sustainability Web site offered Arts 8c Sciences, believes that viable in soils for as long as in Arts 8c Sciences as assis- gene flow is one factor that has 20 years. tant professor. The University became a mem- receive a password. Use your cam- been at work. There also is a great amount of He was previously a visit- ber of the Association for the pus e-mail address as your user- "We are looking for candi- variation in different red rice ing research professor at the Advancement of Sustainability in name. date genes that underlie particu- strains. University of California, Higher Education (AASHE), a The Web site features resources lar traits that differ between the Some look remarkably like cul- Davis. membership-based association to assist campus sustainability ef- two," Olsen said. "Knowing tivated rice and behave like culti- He earned a doctorate in of colleges and universities forts, including a sustainability more about the traits could help vated rice. mathematics from the Uni- working to advance sustainabili- policy bank, a campus sustainabil- in potentially controlling the The plants are as tall as culti- versity of California, Berke- ty in higher education in the ity professional's page, interest weed. We have a key advantage vated rice and flower at the same ley, where he worked under United States and Canada. groups, publications, classroom in this research in that we know time. As such, everyone on the resources and links for virtually Alan Weinstein. the complete cultivated rice These "crop mimics" are diffi- Danforth and School of Medi- every aspect of campus opera- His areas of expertise are genome, so it's fairly easy to tar- cult to spot. cine campuses is covered by tions. get genes of interest." Olsen hopes understanding noncommutative geometry, AASHE membership and may To help keep up with the rap- Olsen and his colleagues, trait differences can lead to eradi- symplectic geometry and access any of the organization's idly evolving world of campus Ana Caicedo, Ph.D., of the Uni- cation of red rice. quantization. member's-only resources. sustainability, AASHE offers a free versity of Massachusetts, and "We're looking for anything He worked on mathemat- To do this, visit aashe.org; weekly e-newsletter called AASHE Yulin Jia, Ph.D., of the U.S. De- that exploits the difference be- ical problems in statistical click on a locked resource (or Bulletin. partment of Agriculture Nation- tween the crop and the weed and thermodynamics while still click on "Member Login" in the It delivers the latest campus al Rice Research Center, will test the way that the weed grows ver- an undergraduate at Peking left column); and at the log-in sustainability news, resources, op- at least two hypotheses. sus the way that the crop grows," University. page, select "Create a new ac- portunities and events from the One is that red rice is rice he said. "That's the way to eradi- count." Follow the directions to United States and Canada. that's gone feral, or gone bad. cate it." 8 recor&wustledu WASHINGTON UNIVERSITY IN ST. LOUIS Feb. 15,2007 Washington People

Leonard Green, Ph.D., has spent much of his career exploring the motivations that drive animal and human behavior. Still, he admits with feigned chagrin, it's his own behavior that sometimes defies rational explanation. "One of the reasons I like working here is that I can get away with saying most anything," he quips, adding that on occasion something he's intended to be funny or instructive has been mis- understood as mean-spirited. "I'm from New York, and in our family we didn't have arguments. We just had lots of very loud discussions, so you're always interrupting people — that's just my style. "Occasionally I do inhibit, though" he continues. "There BY GERRY EVERDING seems to be some small inhibitory center in my brain, although it's clearly not fully developed." Green, professor of psychology in Arts & Sciences, enjoys poking fun at his social shortcomings, but his reputation with colleagues and students leaves little doubt that those who get to know him invari- Leonard Green, Ph.D., talks with Pamela Talley (center), a sophomore double-majoring in psychology ably come to appreciate Rim — and in anthropology, both in Arts & Sciences, and Amanda Calvert, a graduate student in psychology.

Green begged off, saying he had for a joint writing session. Myer- no background in clinical work. son, who can type with all his fin- The psychology of learning Eventually, he relented and offered gers, works the keyboard, while to find students willing to help. Green, a two-fingered typist, is This chance phone call has blos- relegated to working the mouse. even if they don't always get his Stony Brook, where he planned to somed into whole networks of "Most researchers love to do Leonard Green sense of humor. continue his work on human be- autism support services and sanc- experiments, and then they do "Green's undergraduate course, havior. Instead, he was assigned to tioned practicum work that pairs anything to avoid writing up the plays tough with 'The Psychology of Learning,' is the lab of Howard Rachlin, a lead- University students with parents research," Myerson says. "Working one of the most rigorous in the de- ing expert on animal behavior needing autism-related assistance. side-by-side with Len is so much partment, yet students line up to and, as Green would soon learn, a Green now serves on the board fun that I actually look forward to students and get into it," says Henry L. "Roddy" "pigeon guy." of Missouri Families for Effective the writing. It's made us both Roediger III, Ph.D., the James S. "Len and Howie" began crank- Autism Treatment and as faculty much more productive." leaves a lasting McDonnell Distinguished Univer- ing out papers on such issues as adviser for the student-run Night Sharon Stahl, Ph.D., associate sity Professor and former chair of "Economic and Biological Influ- Off Program, which provides free dean of the College of Arts & Sci- psychology. ences on a Pigeon's Key Peck," student babysitters for parents ences, has worked closely with impression "The waiting list is longer than "Commodity-Choice Behavior needing a "night off" from de- Green since 1988. She credits him the number enrolled," he adds. with Pigeons as Subjects" and mands of caring for a child with with making a huge difference in "Len is known to be a superb "Demand Curves for Animal autism. the campus experience for count- teacher." Consumers." Green shrugs off his involve- less students — engaging them in Roediger, now dean of aca- Their work, still influential, has ment, suggesting that he has bene- the classroom, involving them in demic planning in Arts & Sci- been cited hundreds of times. fited most from the experience. He research, helping them cope with ences, credits Green with building Their first published paper is the mentions a time when he scolded serious academic difficulties and student interest in psychology. basis for research on the experi- his daughter for wasting time re- life challenges. "Psychology has more majors mental analysis of commitment reading a silly children's novel in "Len likes to come across as than any other department in Arts and self-control, including Green's one sitting. this real tough guy, like this hard- & Sciences, and Len Green is a big current work on the psychology of Later, he met with parents of nosed guy from New York, but be- part of the reason," Roediger says. discounting, gambling, risk-taking an autistic child and was over- fore it's all over, it's obvious he has "He works very hard in his role as and delay of gratification. whelmed by the realization of a heart of gold," Stahl says. "He's director of undergraduate studies. Green earned a doctorate at what they would have given to see everything this University looks He meets with students, sends out SUNY in 1974. He stayed one year their child read any book. for in its faculty — kind, caring frequent newsletters to keep them as a post-doctoral research associ- "I really don't know that much and very generous with his time." updated on new developments ate before taking a cut in pay to about autism," Green says. "I don't Green admits playing tough and works constantly to improve join Washington University as as- do that much. The parents do with students on occasion, but the major." sistant professor. He since has everything. They're incredible. I've does so, he says, because he takes On faculty here since 1975, published more than 100 articles learned so much about myself just them seriously. He wants them to Green grew up in the Bronx and and book chapters and is editor of from being around them." think deeply about their opinions, attended City College of New his field's most prestigious publi- Green's daughter, Hannah, is 18 to be aware of consequences. Leonard Green, Ph.D. York on a Regents Fellowship, rid- cation, the Journal of the Experi- and a freshman at New York Uni- "Ideas matter a great deal to ing the subway between campus, mental Analysis of Behavior. versity. Her mother, Ana Coelho, me," he says. "You should be pas- Education: Bachelor's, City College of home and his part-time job at a Green's book series, "Advances came here from Portugal to pursue sionate about things, because they New York, 1969; doctorate, State camera shop. in Behavioral Economics," co-ed- graduate work at WUSTL and is a matter." University of New York at Stony At City College, Green took a ited with John Kagel, helped pop- professor of philosophy at St. Louis Often his influence has a last- Brook, 1974 couple of psychology courses and ularize the use of traditional psy- Community College at Florissant ing impression, shaping careers chology lab experiments to inves- Valley. long after graduation. Recent research topics: fell hard for the discipline. "It just struck me as conceptu- tigate economic theories on indi- She and Green once conspired Douglas Johnson, associate • Psychology of tipping, gratuities ally rich," he recalls. "There were vidual behavior. The book in- on a prank that involved Hannah dean of psychology and chair of • Gambling psychology offers insight these intricate theories, but they cludes contributions from noted and Sandra Hale, Ph.D., associate the scientific perspectives program into self-control, risk-taking were well-grounded in empirical economists and psychologists and professor of psychology. at Colgate University, got his start research. It wasn't just specula- argues that economic theories can Hale, a longtime family friend, working in Green's lab as an un- • Holiday giving season complicated tion. There had to be data and the be scientifically tested in the labo- recounts the story this way: "Len dergraduate in the mid-1980s. by shifting norms on gratuities appropriate experimental re- ratory, even using animal experi- Green is the kind of colleague who He went on to earn a doctorate • People willing to wait for money search, and I found the research mentation. would send his 18-month-old at Johns Hopkins University, fol- rewards over others intriguing." In addition to his undergradu- daughter into the middle of a de- lowed by a four-year post-doc at Green's undergraduate honors ate advising roles, Green is direc- velopmental lecture I was giving the National Institutes of Health. thesis involved tor of psychology's study abroad and have her hand me a note that He traces all these accomplish- learning-related program and oversees partner said: You are lecturing about kids. ments to the initial excitement for experiments programs at the University of My name is Hannah, and I is one.' experimental psychology generat- with nursery- Sussex and Exeter in England and Naturally, his daughter was a big ed by a dynamic and caring school children. the University of Queensland in hit, and I was touched that Len and teacher. He admits Australia. He's the longtime cam- Ana would take the time to set this "Len Green played an enor- spending much pus adviser to the national honor up and pull it off without a hitch." mous role in my academic and of his research society in psychology, Psi Chi, and Hale's husband, Joel Myerson, personal growth, is directly re- time playing a founding participant in Cross- Ph.D., research professor of psy- sponsible for my interest in psy- Ep with the chil- ing Forsyth, a campus program chology, is Len's closest research chology and contributed greatly IK. - < *"*^H dren and read- that fosters faculty-student inter- colleague and his inseparable of- to my desire to continue my edu- ■'"■■ v W£k \^ ^^H ing them stories, action on the South 40. fice sidekick. cation beyond Washington Uni- r " but still man- His most rewarding extracur- Because Len and Joel bear a versity," Johnson says. aged to earn a ricular activity may be his work slight resemblance, students have "Len expressed confidence in bachelor's de- on behalf of children with autism. been known to assume they are my mind and abilities at a time fly IB gree in 1969. Like so many of his interests, this twins, and, because their thought when I was less sure than he of He moved on one came by accident: A dis- processes are so interwoven, they my potential. to graduate traught mother called Green by might as well be. "Len Green is the best teacher LL I H fl school at the mistake, thinking the acronym Myerson has published dozens I have ever interacted with, and I State University "ABA" on his resume meant he of articles with Green, but has am certain there are hundreds of Green's family: Ana Coelho and their daughter, of New York was certified to work with autistic never exchanged a draft. other graduates who will echo Hannah. (SUNY) at children. Instead, they meet almost daily this sentiment."