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(877) 889-2288 toll-free 10451 Roselle Street, #300 (858) 642-1988 telephone www.ATSbio.com website San Diego, CA 92121 USA (858) 642-1988 fax [email protected] email Table of Contents

Saporin ...... 5 Secondary Conjugates ...... 21 Saporin ...... 5 Anti-M-ZAP (primary mouse monoclonal IgM )...... 21 Anti-Saporin ...... 5 Fab-ZAP (primary mouse monoclonal IgG , monovalent )22 Targeted Toxins ...... 6 Goat-ZAP (primary goat monoclonal IgG ) ...... 22 Hu g-M -ZAP (primary human monoclonal IgM ) ...... 23 192-IgG-SAP (rat NGFr ) ...... 6 Hum-ZAP (primary : human monoclonal IgG ) ...... 23 Acetylated LDL-SAP (rat microglia ) ...... 7 Mab-ZAP (primary mouse monoclonal IgG ) ...... 24 Anti-CD22-SA P (human CD22 ) ...... 7 Anti-CD25-SAP (human CD25 ) ...... 8 Rab-ZAP (primary rabbit polyclonal IgG )...... 24 Anti-CD25-SAP (mouse CD25 ) ...... 8 Rat-ZAP (primary rat monoclonal IgG ) ...... 25 Anti-CD103-SAP (CD103) ...... 9 Custom Conjugates ...... 25 Anti-DAT-SAP (rat / human dopamine transporter ...... 9 Streptavidin-ZAP (biotinylated material ) ...... 26 Anti-DBH-SAP (r at dopamine beta-hydroxylase )...... 10 Biotinylation Service ...... 26 Anti-SERT-SAP (rat / human SERT) ...... 11 Bombesin-SAP (GRP receptor )...... 11 Control Conjugates ...... 27 CTB-SAP (GM 1 Ganglioside ) ...... 12 Blank-SAP (for peptide conjugates )...... 27 CRF-SAP (CRF receptor 1 ) ...... 12 Goat IgG-SAP ...... 28 CCK-SAP (CCKr1 and CCKr2 )...... 12 Human IgG-SAP ...... 28 Dermorphin-SAP / MOR-SAP (MOR ) ...... 13 Mouse IgG-SAP ...... 29 FGF-SAP (FGF receptor s) ...... 13 Mouse IgM-SAP ...... 29 GAT1-SAP (GABA-1 transporter, GAT-1 )...... 14 Rabbit IgG-SAP ...... 30 Galanin-SAP (galanin-1 receptor )...... 14 Rat IgG-SAP ...... 30 IB4-SAP (a-D-Galacto pyranoside residues ) ...... 15 Fluorescent Conjugates ...... 31 Leptin-SAP (leptin receptor )...... 15 Custom Fluorescent Labeling ...... 32 Mac-1-SAP (mouse / human CD11b receptor ) ...... 16 Antibodies ...... 34 Mac-1-SAP (rat CD11b receptor )...... 16 ME20.4-SAP (mammalian NGFr ) ...... 17 Proteins, Peptides & Antigens ...... 46 Melanopsin-SAP (melanopsin , ipRGCs )...... 17 Index ...... 59 mu p75-SAP (mouse NGFr )...... 18 NPY-SAP (neuropeptide Y receptor )...... 18 Oxytocin-SAP (oxytocin receptor )...... 19 OX7-SAP (multi-species Thy-1.1 )...... 19 SSP-SAP (substance P receptor ) ...... 20 SP-CTA (substance P receptor )...... 20

Table of Contents 2 The Technology 3 Saporin 4 Targeted Toxins 5 Secondary Conjugates 20 Control Conjugates 26 Fluorescent Conjugates 30 Antibodies 33 Proteins, Peptides & Antigens 45 Index 58 Page 3 The Technology

Follow these simple illustrations to understand how this advanced targeting system can work for you. Or watch a multi-media presentation demonstrating this technology at www.ATSbio.com/movie

1) 2) 3) 4)

Get an antibody specific to your cell type. Use a potent toxin that is ATS puts them The conjugate seeks together out target markers Or use anything safe in the lab, to make a powerful on the cell surface. that binds to a cell but lethal inside a cell. targeting agent. surface molecule and is internalized.

5) 6) 7) 8)

Once attached to its target receptor, the The bond between The ribosomes are conjugate is internalized. The SAPORIN SAPORIN and the inactivated Cells which do not have conjugate enters the targeting agent is resulting in the target receptor cell. broken in the cell death. will not be affected. endosome. Pretty simple, huh? Now just imagine the targets you can eliminate in your research! Page 4 Saporin (pronounced )

Saporin (Cat. #PR-01: 100 µg)

Saporin is a ribosome-inactivating protein, molecular weight 30 kDa, from seeds of the plant Saponaria officinalis .

Effective Tool • An experimental control with targeted toxins • Safe for laboratory use under normal safety conditions • LD 50 in mice at 4 mg/kg • Does not have a method of cell entry on its own Sample protocol For most targeted toxins, there are control conjugates available (pp. 23-25); these are the most accurate controls to use. For a few products, saporin is used as control. Calculate amount of saporin needed on a molar basis. For example, FGF-SAP (Cat. #IT-38) has an average mol. wt. of 63 kDa, and 71% of that is saporin (approximately 1.5 molecules of saporin per molecule of cytokine). For injections of 5 µg of immunotoxin, an appropriate control quantity would be 3.6 µg.

Anti-Saporin (Cat. #AB-15; AB-15 AP ; AB-15 hRP ; AB-17 AP , AB-41 AP )

Specificity AB-1 5Ap Goat Anti-Saporin, • goat anti-saporin, 100 µl (Cat. #AB-15) affinity purified • goat anti-saporin affinity purified, 50 µg (Cat. #AB-15 AP ) Lane 1: Molecular weight standards (Invitrogen SeeBlue) • goat anti-saporin HRP-labeled, 200 µg (Cat. #AB-15 HRP ) Lane 2: 50 ng of Saporin • chicken anti-saporin affinity purified, 50 µg (Cat. #AB-17 AP ) probed with Goat anti-Saporin • rabbit anti-saporin affinity-purified, 50 µg (Cat. #AB-41 AP ) affinity purified (AB-15 Ap ) at 1.0 µg/ml Applications Lane 3: 25 ng of Saporin • immunoblotting, ELISA, immunohistochemistry probed with Goat anti-Saporin affinity purified (AB-15 Ap ) at 1.0 AB-1 5hrp Goat Anti- µg/ml Saporin, hrp-labeled Saporin (200, 100, 50, and 25 ng) was run on a 10% SDS-pAGE gel AB-17 Ap Chicken and transferred to pVDF membrane. Anti-Saporin, The blot was blocked with 4% affinity-purified NFM/TBS, then incubated overnight Lane 1: Molecular with 0.5 µg/ml (Lanes 11-15), 1 µg/ml weight standards (Lanes 6-10), or 5 µg/ml (Lanes 1-5) (Invitrogen of antibody. The blot was washed SeeBlue) and developed with 4-chloro-1- naphthol and hydrogen peroxide. Lane 2: 100 ng of Saporin probed Lane 1, 6, 11: Molecular weight with AB-17 Ap at a standards (Invitrogen SeeBlue) concentration of Lane 2, 7, 12: 200 ng Saporin 0.5 µg/ml Lane 3, 8, 13: 100 ng Saporin Lane 4, 9, 14: 50 ng Saporin Page 5 Lane 5, 10, 15: 25 ng Saporin Targeted Toxins

192-IgG-SAP TARGET: rat NGFr a chemical conjugate of a mouse monoclonal antibody to rat p75 NTR and the ribosome-inactivating protein, saporin Intraventricular injection of 192-IgG-SAP results in almost complete elimination of low affinity nerve growth factor receptor (p75 NTR )-positive cells in the rat basal forebrain. This immunotoxin provides researchers with a powerful lesioning tool — more specific and effective than chemical, surgical or electrolytic lesioning.

192-IgG-SAP (conjugate alone) Cat # Units IT-01-25 25 micrograms IT-01-100 100 micrograms IT-01-250 250 micrograms

Kit: conjugate and controls (saporin, control conjugate)

CONTrOL TrEATED Cat # Units p75 NTR -positive neurons of rat cholinergic icv injection of 192-Saporin KIT-01-25 25 micrograms forebrain >95% elimination of target neurons KIT-01-100 100 micrograms Photos supplied by C. Wrenn, R.G. Wiley KIT-01-250 250 micrograms

related products: Cy3-labeled 192-IgG (Cat. #FL-01), Alexa488-labeled 192-IgG (Cat. #FL-03), Mouse IgG-SAp (Cat. #IT-18), mu p75-SAp (Cat. #IT-16), ME20.4-SAp (Cat. #IT-15)

Page 6 Acetylated LDL-SAP TARGET: rat microglia a chemical conjugate of acetylated human low density lipoprotein and the ribosome-inactivating protein, saporin Acetylated LDL-Saporin (acetylated LDL-SAP) has been used effectively to eliminate microglia from primary cultures of rat hippocampal neurons, while having no deleterious effect on neurons or astroglia. After 24 hours exposure, 3 µg/ml of acetylated-LDL-SAP selectively kills more than 90% of microglia cells.

Acetylated LDL-SAP (conjugate alone) Cat # Units IT-08-25 25 micrograms IT-08-100 100 micrograms IT-08-250 250 micrograms Kit: conjugate and control (saporin) Cat # Units

NR8383 cells are plated at 10 4 cells/well and incubated overnight. KIT-08-25 25 micrograms Saporin and acLDL-SAp are added in 10-µl volumes and the plates are KIT-08-100 100 micrograms incubated 72 hours. KIT-08-250 250 micrograms pMS/MTS developing reagent is added and the plates are incubated two hours, then read at 490 nm. Data analyzed by Prism software.

Anti-CD22-SAP TARGET: human CD22 a chemical conjugate of a mouse monoclonal antibody to Human CD22 (Cat. #AB-36) and the ribosome- inactivating protein, saporin CD22 is characterized as a doublet of 130/140 kDa and is expressed on the surface of normal human B-cells and some neoplastic B-cell lines and tumors. This targeted toxin recognizes and specifically eliminates cells that possess the group-A epitope of the human B-cell antigen, CD22.

Anti-CD22-SAP (conjugate alone) Daudi cells, a Burkitt lymphoma cell line, were plated at 3000 cells per Cat # Units well and were allowed to acclimate. IT-37-25 25 micrograms Samples were added at the indicated concentrations and cells IT-37-100 100 micrograms were incubated for 72 hours. MTS IT-37-250 250 micrograms (promega) was added and, after color development, wells were read Kit: conjugate and controls with a Molecular Dynamics SpectraMax 340. ED50's of each (saporin, antibody, control conjugate) compound are color-coded. Data Cat # Units analysis is by pRISM (Graphpad). KIT-37-25 25 micrograms KIT-37-100 100 micrograms KIT-37-250 250 micrograms related products: Anti-CD22 (Cat. #AB-36), Mouse IgG-SAp (Cat. #IT-18)

Page 7 Anti-CD25-SAP, human TARGET: human CD25 a chemical conjugate of a monoclonal antibody to human CD25 ( Tac , IL-2 receptor, Cat. #AB-18) and the ribosome-inactivating protein, saporin The CD25 monoclonal antibody inhibits the proliferation of Interleukin-2 (IL-2)-dependent human continuous T-cell lines. It blocks the human T-cell receptor for IL-2 by binding to the alpha-chain of the IL-2 receptor. Immunotoxins made with an antibody to the IL-2 receptor have been suggested for clinical use in the treatment of T-cell leukemias and lymphomas. Anti-CD25-SAP , human (conjugate alone) Cat # Units IT-24-25 25 micrograms IT-24-100 100 micrograms IT-24-250 250 micrograms

Kit: conjugate and controls (saporin, antibody, control conjugate) Cat # Units Cytotoxicity of anti-CD25-SAp and of non-conjugated saporin to SR cells in culture. Cells were plated at 5000 cells per well and allowed to acclimate. KIT-24-25 25 micrograms Samples were added at the indicated concentrations and cells were incubated KIT-24-100 100 micrograms for 72 hours. MTS (promega) was added and, after color development, plates were read with a Molecular Dynamics SpectraMax 340. ED 50' s of each KIT-24-250 250 micrograms compound are color-coded. Data analysis is by pRISM (Graphpad). related products: human-specific anti-CD25 (Cat. #AB-18), mouse-specific anti-CD25 (Cat. #AB-19), Mouse IgG-SAp (Cat. #IT-18)

Anti-CD25-SAP, mouse TARGET: mouse CD25 a chemical conjugate of a monoclonal antibody to mouse CD25 (Tac, IL-2 receptor, Cat. #AB-19) and the ribosome-inactivating protein, saporin The CD25 monoclonal antibody inhibits the proliferation of Interleukin-2 (IL-2)-dependent continuous T-cell lines. It blocks the T-cell receptor for IL-2 by binding to the alpha-chain of the IL-2 receptor. Immunotoxins made with an antibody to the IL-2 receptor have been suggested for clinical use in the treatment of T-cell leukemias and lymphomas, and are potently cytotoxic to mouse activated T-cells. HT-2 cells were plated at 2000 Anti-CD25-SAP , mouse cells per well and incubated (conjugate alone) overnight. Reagents were added as indicated, and incubated for 72 Cat # Units hrs. percent of live cells was IT-29-25 25 micrograms evaluated by developing with a IT-29-100 100 micrograms MTS/pMS mixture, and comparison to cells in wells that IT-29-250 250 micrograms received no treatment. Data was collected on a Molecular Devices Kit: conjugate and controls Spectramax plate reader with (saporin, antibody, control conjugate) Softmax software, and evaluated with pRISM software (Graphpad). Cat # Units KIT-29-25 25 micrograms related products: human-specific anti-CD25 (Cat. #AB-18), KIT-29-100 100 micrograms mouse-specific anti-CD25 (Cat. #AB-19), KIT-29-250 250 micrograms rat IgG-SAp (Cat. #IT-17) Page 8 Anti-CD103-SAP TARGET: CD103 a chemical conjugate of the antibody to CD103 and the ribosome-inactivating protein, saporin. Anti-CD103-SAP eliminates cells that express CD103. CD103, also know as integrin, alpha-E (ITGAE) binds integrin beta 7 (ß7-ITGB7) to form the complete heterodimeric integrin molecule aEß7. The nondepleting CD103 monoclonal antibody, M290, binds a discrete and stable subset of human CD8+ cytotoxic T lymphocytes. Expression by these cells is initiated and maintained by bioactive TGF-[beta]. Immunotoxins made with this antibody help identify the role of integrin CD103 in promoting organ allograft rejection and in graft-versus-host disease.

Anti-CD103-SAP Kit: conjugate and controls (conjugate alone) (saporin) Cat # Units Cat # Units IT-50-25 25 micrograms KIT-50-25 25 micrograms IT-50-100 100 micrograms KIT-50-100 100 micrograms IT-50-250 250 micrograms KIT-50-250 250 micrograms

Anti-DAT-SAP TARGET: rat / human dopamine transporter a chemical conjugate of a rat monoclonal antibody to the second extracellular loop of the dopamine transporter (DAT-ECD, Cat. #AB-N17) and the ribosome-inactivating protein, saporin The dopamine transporter (DAT ) is a sodium-dependent reuptake carrier that is suspected to play a role in such neurologic and psychiatric disorders as Parkinson's disease, Tourette's syndrome, schizophrenia, and addiction. It is a 12-transmembrane domain transporter with the N- and C-terminus regions located within the cytoplasm. Because of its importance in dopamine use, DAT is an identifier of dopaminergic neurons. This toxin is highly specific for cells that express DAT, including mesencephalic dopamine neurons of the substantia nigra, pars compacta, and ventral tegmental area. Anti-DAT-SAP (conjugate alone) Representative sections stained for tyrosine Cat # Units hydroxylase from rats with IT-25-25 25 micrograms intrastriatal injections of anti- DAT-SAp 2 weeks prior to IT-25-100 100 micrograms sacrifice. panels A, C, and E IT-25-250 250 micrograms are ipsilateral to the striatal injections. panels B, D, and F Kit: conjugate and controls are contralateral, from the (saporin, antibody, control conjugate) same sections. The anti-DAT- SAp doses were 2.8 μg in A, Cat # Units 0.56 mg in C, and 0.28 μg in KIT-25-25 25 micrograms E. Note loss of dopaminergic neurons from the ipsilateral KIT-25-100 100 micrograms substantia nigra, pars KIT-25-250 250 micrograms compacta (arrowheads) with the greatest extent of cell loss related products: in A and the least in E. The anti-DAT-ECD (Cat. #AB-N17), magnification bar in F anti-DAT-NT (Cat. #AB-N18), indicates 100 μm and applies to all panels. rat IgG-SAp (Cat. #IT-17) Photo provided by R.G. Wiley

Page 9 Anti-DBH-SAP TARGET: rat dopamine beta-hydroxylase a chemical conjugate of the mouse monoclonal antibody to dopamine beta-hydroxylase and the ribosome- inactivating protein, saporin Anti-dopamine beta-hydroxylase-saporin (anti-DBH-SAP) is a highly specific noradrenergic lesioning agent. It specifically targets rat* cells that express dopamine beta-hydroxylase . This vesicular enzyme is exposed to the exterior milieu upon release of noradrenaline and thus allows these cells to be targeted with saporin. The specificity of the immunotoxin correlates well with uptake of the antibody when injected intraventricularly. After systemic administration, animals have a massive CONTrOL locus coeruleus pBS-injected (icv) reduction in plasma norepinephrine levels, indicating efficient targeting rat; stained for tyrosine hydroxylase and sympathectomy. Unlike other lesioning methods, this molecular lesioning agent assures definitive ablation of the target neurons. * Also known to react with cow and sheep, other species not confirmed.

Anti-DBh-SAP Kit: conjugate and controls (conjugate alone) (saporin, control conjugate) Cat # Units Cat # Units TrEATED icv injection of anti-DBH-SAp IT-03-25 25 micrograms KIT-03-25 25 micrograms >95% elimination of target neurons IT-03-100 100 micrograms KIT-03-100 100 micrograms IT-03-250 250 micrograms KIT-03-250 250 micrograms Photos supplied by C. Wrenn, R.G. Wiley related product: Mouse IgG-SAp (Cat. #IT-18)

Custom Conjugate Couldn’t find a toxin for your target? Create your own targeted toxin using Secondary Conjugates and YOUR targeting vehicle. This can be a primary antibody, peptide or protein ligand, lectin, or whatever else binds to the cell surface. When the in vitro results confirm the desired specificity, contact ATS to order a custom conjugate: YOUR targeting vehicle conjugated to saporin. Email ATS ([email protected]) or call toll-free (877) 889-2288 to discuss your project. All discussions and services can be covered with a confidentiality agreement.

Page 10 Anti-SERT-SAP TARGET: rat / human serotonin re-uptake transporter a chemical conjugate of a monoclonal antibody to the serotonin CONTrOL. transporter (Cat. #AB-N09) and the ribosome-inactivating protein, saporin The control Anti-SERT-SAP utilizes a monoclonal antibody to the fourth rat brain extracellular domain of the serotonin re-uptake transporter (SERT) section, stained for and eliminates SERT-expressing cells in vitro and in vivo . SERT is TpOH, the major determinant of serotonin inactivation following release at received no synapses, is the site of action for many tricyclic antidepressants and injection of anti-SERT- the SSRIs (serotonin-selective reuptake inhibitors), and is also SAp. targeted by a number of psychostimulants including cocaine, TrEATED. methylphenidate, and MDMA ‘ecstasy.’ SERT is produced from a The anti- single gene and is expressed in both the CNS and GI system. SERT-SAp Decreased serotonergic neurotransmission has been proposed to treated rat received play a key role in the etiology of depression. Recent findings two suggest that SERT might be linked to both neurotic and sexual adjacent behavior as well as to obsessive-compulsive disorder (OCD). 100-nl injections of Anti-SERT-SAP Kit: conjugate and controls anti-SERT- (conjugate alone) (saporin, antibody, control conjugate) SAp (1 mM) into medullary raphe at the level of Cat # Units Cat # Units the caudal part of facial nucleus. The injections were 2 weeks prior to sacrifice. Treated rats IT-23-25 25 micrograms KIT-23-25 25 micrograms had a significant reduction in the ventilatory IT-23-100 100 micrograms KIT-23-100 100 micrograms response to breathing 7% CO 2 during both sleep and wakefulness. These data show that IT-23-250 250 micrograms KIT-23-250 250 micrograms TpOH ir neurons in the medullary raphe are involved in the ventilatory response to systemic SERT Peptide hypercapnia. (for control in experiments using anti-SERT) Photo provided by Eugene E. Nattie. Cat # Units related products: PR-03 25 micrograms anti-SErT (Cat. #AB-N09), Mouse IgG-SAp (Cat. #IT-18)

Bombesin-SAP TARGET: GRP receptor a chemical conjugate of bombesin and the ribosome-inactivating protein, saporin Bombesin is a 14-amino-acid peptide found in brain tissue and the gastrointestinal tract. This toxin specifically targets GRP receptor - positive cells. All other cells are left untouched. Bombesin-SAP Kit: conjugate and controls (conjugate alone) (saporin, control conjugate) Cat # Units Cat # Units IT-40-25 25 micrograms KIT-40-25 25 micrograms IT-40-100 100 micrograms KIT-40-100 100 micrograms IT-40-250 250 micrograms KIT-40-250 250 micrograms related product: Blank-SAp (Cat. #IT-21) Selective ablation of Grpr+ neurons in the spinal cord. (A-B) GRpR expression detected by in situ hybridization was significantly reduced in lamina I of mice treated with Bombesin-SAp compared with mice treated with Blank-SAp. (C-D) NK1 receptor expression detected by immunocytochemistry in the dorsal horn was similar between the two groups. Photo provided by Z-F Chen, Y-G Sun, Z-Q Zhao, X-L Meng, J Yin, X-Y Liu. Washington University Pain Center School of Medicine. Page 11 CCK-SAP TARGET: CCKr1 and CCKr2 a chemical conjugate of sulfonated CCK and the ribosome-inactivating protein, saporin Cholecystokinin (CCK ) is widely distributed in the central nervous system and the gastrointestinal tract. The 33-amino acid peptide contains a carboxyl terminal octapeptide sequence Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe- NH 2 which confers the biological CCK-SAP Kit: conjugate and controls activity of CCK, and where the (conjugate alone) (saporin, control conjugate) tyrosine residue occurs in sulfated Cat # Units Cat # Units form. This octapeptide, CCK 8(SO 3), IT-31-25 25 micrograms KIT-31-25 25 micrograms has high affinity for the two IT-31-100 100 micrograms KIT-31-100 100 micrograms structurally-defined CCK receptor IT-31-250 250 micrograms KIT-31-250 250 micrograms types, CCK 1 and CCK 2. This toxin targets cells that recognize sulfonated CCK. related product: Blank-SAp (Cat. #IT-21)

CRF-SAP TARGET: corticotropin-releasing factor receptor 1 a chemical conjugate of human/rat CRF to the ribosome-inactivating protein, saporin Corticotropin-releasing hormone/factor CRF-SAP Kit: conjugate and controls (CRH/ CRF ) is the principal (conjugate alone) (saporin, control conjugate) neuropeptide involved in regulating the Cat # Units Cat # Units stress response. It stimulates ACTH IT-13-25 25 micrograms KIT-13-25 25 micrograms release from the pituitary gland. When IT-13-100 100 micrograms KIT-13-100 100 micrograms centrally administered to animals it IT-13-250 250 micrograms KIT-13-250 250 micrograms produces somatic changes analogous to those seen in both depression and anxiety. In humans, it is capable of related product: reproducing the hormonal changes which are characteristically seen in Blank-SAp (Cat. #IT-21) depressed patients. CRF-SAP eliminates cells expressing the CRF 1 receptor.

CTB-SAP TARGET: GM 1 Ganglioside a chemical conjugate of the cholera toxin B-subunit and the ribosome-inactivating protein, saporin Cholera toxin B (CTB ) binds the ganglioside GM 1. This molecule is found on cells such as motoneurons, sympathetic pre-ganglionic neurons, as well as cells in the intestinal epithelium. CTB-SAP causes ablation of any cell type expressing GM 1, including preganglionic neurons, motoneurons, and astrocytes.

CTB-SAP (conjugate alone) HS294T cells were plated at 1000 Cat # Units cells per well at 90 µl in a 96-well plate and incubated overnight at IT-14-25 25 micrograms 37°C with 5% CO 2. 10 µl CTB, CTB- IT-14-100 100 micrograms SAp, and CTB-SAp in the presence of CTB were added to separate IT-14-250 250 micrograms plates in dilution curves and the Kit: conjugate and control plates were incubated 72 hours at 37°C with 5% CO 2. The plates were (saporin) developed with MTS/pMS and read Cat # Units at 490 nM in a SpectraMax 340 plate reader (Molecular Devices). KIT-14-25 25 micrograms Data analyzed by prism (Graphpad).

KIT-14-100 100 micrograms U.S. Patent 6.376,460 "Method of Modulating Cellular Activity" protects methods of peripheral injection of subjects using KIT-14-250 250 micrograms this neuronal tracer. Before using these methods please contact Flinders Technologies Pty. Ltd. for license information. [email protected] Page 12 Dermorphin-SAP / MOR-SAP TARGET: mu-opioid receptor (MOR ) a chemical conjugate of dermorphin and the ribosome-inactivating protein, saporin Dermorphin-SAP targets and eliminates cells expressing the mu opioid receptor (MOR). MOR-expressing neurons have long been considered some of the most important cells in the nervous systems because of their participation in pain, pain control, addiction, gastrointestinal motility, and mast cell function, among others. This specific cytotoxin provides new methods for understanding these neurons and how they work. . G . R

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Dermorphin-SAP / MOR-SAP Kit: conjugate and controls (conjugate alone) (saporin, control conjugate) Cat # Units Cat # Units related product: IT-12-25 25 micrograms KIT-12-25 25 micrograms Blank-SAp (Cat. #IT-21) IT-12-100 100 micrograms KIT-12-100 100 micrograms IT-12-250 250 micrograms KIT-12-250 250 micrograms

FGF-SAP TARGET: FGF receptor s a chemical conjugate of rat FGF-2 and the ribosome-inactivating protein, saporin FGF-2, or basic fibroblast growth factor , binds all of the FGF receptors with high affinity. We have used this molecule to produce FGF-SAP, which has a healthy experimental publication record (“FGF” and “saporin” in PubMed: 25 hits). It has been used to clean primary cultures of fibroblasts. It was important in determining the role of smooth muscle cells in restenosis of damaged vasculature. It was widely used in vivo for the elimination of FGF receptor-expressing cells, including neuronal cell types, cancer cells, and lens epithelial cells. FGF-2 has been well characterized demonstrating binding to all four of the FGF high-affinity tyrosine kinase transmembrane receptors including binding to FGF receptor-5 with lower affinity. FGF-SAP eliminates FGF receptor-expressing cells including neuronal cell types, cancer cells, FGF-SAP and lens epithelial cells with cross reactivity in several mammalian (conjugate alone) species. This conjugate is useful for the study of systems biology. Cat # Units NIH/3T3 cells, a mouse IT-38-25 25 micrograms embryonic fibroblast cell line, are plated at 500 cells/90 µl and IT-38-100 100 micrograms incubated overnight. FGF-SAp, a IT-38-250 250 micrograms chemical conjugate of rat FGF-2 and saporin, and FGF+SAp, Kit: conjugate and controls containing both constituents in (saporin) solution, are added to the plates in 10-µl volumes. plates are Cat # Units incubated 72 hours. pMS/MTS developing reagent is added and KIT-38-25 25 micrograms the plates are incubated 1-2 KIT-38-100 100 micrograms hours, then read at 490 nm in a KIT-38-250 250 micrograms plate reader. Data analysis was done by pRISM (Graphpad). Page 13 Galanin-SAP TARGET: galanin-1 receptor a chemical conjugate of rat galanin and the ribosome-inactivating protein, saporin Galanin-SAP eliminates cells expressing the galanin-1 receptor. Galanin is a 29-amino acid peptide (30 amino acids in humans) implicated in a variety of functions including nociception, appetite, learning, and memory. It is widely distributed throughout the neural and endocrine systems, playing roles in the secretion of insulin, somatostatin, glucagon, dopamine, and growth hormone, and inhibiting Galanin-SAP the release of acetylcholine and substance P from myenteric neurons. (conjugate alone) Bowes melanoma cells were plated at 1000 cells/90 µl/well in a Cat # Units 96-well plate and incubated IT-34-25 25 micrograms overnight. Saporin, galanin-SAp, or galanin-SAp + 1 µM galanin IT-34-100 100 micrograms peptide were added to the plates in IT-34-250 250 micrograms 10 µl volumes, and the plates were incubated for 72 hours. The plates Kit: conjugate and controls were developed with pMS/MTS for (saporin, control conjugate) 30 minutes to 1 hour, then read at 492 nm in a plate reader. Data Cat # Units analysis was done by pRISM (Graphpad, San Diego). KIT-34-25 25 micrograms KIT-34-100 100 micrograms related product: Blank-SAp (Cat. #IT-21) KIT-34-250 250 micrograms

GAT1-SAP TARGET: GABA-1 transporter, GAT-1 a chemical conjugate of an affinity purified rabbit polyclonal antibody against a GAT-1 peptide sequence (Cat. #AB-N37) and the ribosome-inactivating protein, saporin GAT-1 is a sodium-coupled neurotransmitter transporter responsible for moving γ-aminobutyric acid (GABA) across cell membranes. GABA is the predominant inhibitory neurotransmitter in the mammalian central nervous system. GAT -1 is widely distributed in both the central and peripheral nervous systems. GAT-1 and GABA are present in numerous neuronal pathways, some of which are implicated in epilepsy, sleep disorders, neuropathic pain, and attention deficit disorders. This targeted toxin recognizes cells that express the GABA-1 transporter, GAT-1. It has been tested in rat. The peptide used as an antigen has 100% sequence homology between rat, human, mouse, and bovine GAT-1. Immunocytochemistry GAT1-SAP following sham surgery (conjugate alone) (top row) or administration of GAT1-SAp (bottom Cat # Units row, 325 ng/µl) into the IT-32-25 25 micrograms medial septum-diagonal band of Broca (MSDB). IT-32-100 100 micrograms Staining of parvalbumin- IT-32-250 250 micrograms immunoreactive neurons in the MSDB was Kit: conjugate and controls dramatically reduced (saporin, antibody, control conjugate) following GAT1-SAp (left). parvalbumin-ir neurons in Cat # Units the MSDB are GABAergic septohippocampal KIT-32-25 25 micrograms neurons. In contrast to parvalbumin-ir neurons, neither cholinergic neurons (ChAT-ir, KIT-32-100 100 micrograms middle) nor calbindin-ir neurons (right) were altered following GAT1-SAp in the MSDB. KIT-32-250 250 micrograms Scale bar - 200 µm. Figure provided by Kevin Pang. related products: rabbit IgG-SAp (Cat. #IT-35), Anti-GAT-1 (Cat. #AB-N37) Page 14 IB4-SAP TARGET: a-D-Galacto pyranoside residues a chemical conjugate of the B4 lectin (from Griffonia (Bandeiraea) simplicifolia ) and the ribosome- inactivating protein, saporin IB4-SAP specifically eliminates IB4-positive neurons, while sparing the IB4-SAP peptidergic neurons. Upon binding to the a-D-Galactopryanoside residues (conjugate alone) expressed on the cell surface, IB4-SAP becomes internalized and saporin Cat # Units inhibits protein synthesis, resulting in the elimination of the neurons. The IT-10-25 25 micrograms cytotoxin is extremely potent, with an ED 50 in the low picomolar range IT-10-100 100 micrograms for some a-D-Galactopyranoside-expressing cells in vitro . IT-10-250 250 micrograms KNRK cells were plated at 2500 cells per 90 µl per well Kit: conjugate and control in a 96-well plate and (saporin) incubated overnight. IB4-SAp and saporin were added in Cat # Units 10 µl volumes, and the plates KIT-10-25 25 micrograms were incubated for 72 hours. The plates were developed KIT-10-100 100 micrograms with pMS/MTS and read at KIT-10-250 250 micrograms 490 nm in a plate reader. Data analysis was done by pRISM (Graphpad, San IB4 Diego). Cat # Units U.S. Patent 6.376,460 "Method of Modulating Cellular Activity" protects methods of peripheral injection of subjects using this neuronal tracer. Before using these methods please contact Flinders Technologies Pty. Ltd. for license information. [email protected] PR-02 1 milligram

Leptin-SAP TARGET: leptin receptor a chemical conjugate of recombinant mouse leptin and the ribosome-inactivating protein, saporin Leptin is a 16 kDa protein hormone that activates leptin receptors, and plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism. Leptin inhibits the activity of neurons that contain neuropeptide Y (NPY) and agouti-related peptide (AgRP), and increases the activity of neurons expressing α- melanocyte-stimulating hormone ( α- MSH), and thereby is a very influential mediator of satiety. This new product could be used to eliminate leptin receptor-expressing cells as an excellent complement to NPY-SAP and Oxytocin-SAP in studying satiety, appetite, and metabolism. Effects of unilateral Lep-SAp injection Leptin-SAP into Arc on α- MSH and AGRp (conjugate alone) expression. (A) Representative Cat # Units photomicrographs of α- MSH and AGRp cell bodies after unilateral injection of IT-47-25 25 micrograms Lep-SAp into Arc in Sprague Dawley IT-47-100 100 micrograms (S/D) or Zucker fa/fa (Zucker) rats. (B) Numbers of α- MSH- and AGRp-positive IT-47-250 250 micrograms cell bodies in the Arc of S/D and Zucker rats ipsilateral and contralateral to Lep- Kit: conjugate and control SAp injection. In S/D rats, but not (saporin) Zucker fa/fa rats, Lep-SAp significantly decreased the numbers of α- MSH- and Cat # Units AGRp-positive cells in Arc on the KIT-47-25 25 micrograms injected side, compared to the uninjected side. KIT-47-100 100 micrograms * p < 0.01; unpaired t-test vs. control non- KIT-47-250 250 micrograms injection side. Calibration bar = 100 µm . related products: NpY-SAp (Cat. #IT-28), Figure provided by AJ Li, QW, TT Dinh, S Page 15 Oxytocin-SAp (Cat. #IT-46) Ritter; Washington State University. Mac-1-SAP mouse/human TARGET: mouse / human mac-1 (CD11b) receptor a chemical conjugate of the rat monoclonal antibody to CD11b (Cat. #AB-N05) and the ribosome- inactivating protein, saporin The antibody is from the well-characterized M1/70 clone, and has been created by immunization from mouse macrophages, but reacts well with the human epitope also. It does not recognize the rat form. The immunotoxin is extremely potent, with an ED 50 of 5 pM for a mouse monocytic cell line, more than five orders of magnitude more toxic Mac-1-SAP mouse/human than non-targeted saporin. (conjugate alone) MuMo cells, mouse Cat # Units monocytes, are plated at 2500 cells/well and IT-06-05 5 micrograms incubated overnight. IT-06-25 25 micrograms Reagents were added in 10 µl volumes at the indicated IT-06-100 100 micrograms concentrations and incubated for 72 hours. MTS/pMS developing Kit: conjugate and controls reagent was added and the (saporin, antibody, control conjugate) plates read on a Molecular Diagnostics Spectramax Cat # Units plate reader with SoftMax KIT-06-25 25 micrograms software. Data was analyzed KIT-06-100 100 micrograms by pRISM (Graphpad). related products: anti-Mac-1 mouse/human (Cat #AB-N05), anti-Mac-1 rat (Cat. #AB-N06), rat IgG-SAp (Cat. #IT-17)

Mac-1-SAP rat TARGET: rat mac-1 (CD11b) receptor a chemical conjugate of mouse monoclonal antibody to CD11b (Cat. #AB-N06) and the ribosome- inactivating protein, saporin This immunotoxin recognizes the rat Mac-1 (CD11b) receptor. The antibody was developed in mice immunized with rat neutrophils. It does not cross-react with the human or mouse epitope. The immunotoxin is extremely potent, three orders of Mac-1-SAP rat (conjugate alone) magnitude more effective than non-targeted saporin and an ED 50 of 6 pM in rat macrophages in vitro . Cat # Units NR8383 cells, rat IT-33-05 5 micrograms macrophages, are plated at IT-33-25 25 micrograms 10000 cells/well and incubated IT-33-100 100 micrograms overnight. Mac-1-SAp is added in 10 µl volumes and the plates are incubated 72 hours. Kit: conjugate and controls pMS/MTS developing reagent (saporin, antibody, control conjugate) is added and the plates are incubated 1-2 hours, then read Cat # Units at 490 nm in a plate reader. KIT-33-25 25 micrograms Data analysis was done by KIT-33-100 100 micrograms pRISM (Graphpad). KIT-33-250 250 micrograms related products: anti-Mac-1 rat (Cat #AB-N06), anti-Mac-1 mouse/human (Cat. #AB-N05), Mouse IgG-SAp (Cat. #IT-18)

Page 16 ME20.4-SAP TARGET: mammalian NGFr a chemical conjugate of the p75 NTR monoclonal antibody (Cat. #AB-N07) and the ribosome-inactivating protein, saporin This immunotoxin is a powerful lesioning tool and is active in several species, including rabbit and primate. Intraventricular injection of ME20.4-SAP results in elimination of low affinity nerve growth factor receptor (p75 NTR )-positive cells in rabbit. Tissue-directed injection in primates causes loss of p75 NTR -positive neurons. It is useful in immunostaining, immunoprecipitation, and inhibits the binding of NGF to p75 NTR .

related products: anti-NGFr (Cat. #AB- ME20.4-SAP N07), Mouse IgG-SAp (Cat. #IT-18), 192-IgG- (conjugate alone) SAp (Cat. #IT-01), mu p75-SAp (Cat. #IT-16) Cat # Units A,B: rabbit nbm area in control (A) and treated (B) IT-15-25 25 micrograms animals, stained for AChE. Note marked depletion of IT-15-100 100 micrograms nbm neurons in the latter. C,D: rabbit nbm in control (C) and treated (D) animals, IT-15-250 250 micrograms stained immunohistochemically for p75 NTR . Note depletion of neurons in the treated animal. Kit: conjugate and controls E,F: frontal cortex from control (E) and treated (F) (saporin, antibody, control conjugate) animals, stained for AChE. Note eradication of cholinergic fibers in the latter. Cat # Units G,H: A β deposition in cerebral cortex of lesioned KIT-15-25 25 micrograms animals. A β is deposited in blood vessel walls (G) and KIT-15-100 100 micrograms in the perivascular neurophil (H). KIT-15-250 250 micrograms Photos supplied by Dr. Thomas Beach

Melanopsin-SAP TARGET: melanopsin (ipRGCs ) a chemical conjugate of an affinity-purified rabbit polyclonal antibody to mouse melanopsin (Cat. #AB-N39) and the ribosome-inactivating protein, saporin Melanopsin-SAP specifically eliminates intrinsically photosensitive retinal ganglion cells (ipRGCs) that express melanopsin. The ipRGCs, with their amazing long processes, are involved in the perception of light and dark and are circadian rhythm determinants. Melanopsin-SAP (conjugate alone) Cat # Units IT-44-50 50 micrograms IT-44-100 100 micrograms IT-44-250 250 micrograms Kit: conjugate and controls (saporin, antibody and control conjugate) A saporin/anti-melanopsin (UF008) conjugate destroys cultured RGC- Cat # Units 5 cells in a dose-dependent KIT-44-50 50 micrograms manner. Cultures of RGC-5 cells, either stably expressing or not KIT-44-100 100 micrograms expressing mouse melanopsin, KIT-44-250 250 micrograms were exposed to Melanopsin-SAp for 4 days. The concentrations of related products: conjugates are shown above each Affinity-purified Anti-Melanopsin (Cat. #AB-N39), column and the experiments were rabbit-IgG-SAp (Cat. #IT-35) done in triplicate. Each panel represents a randomly selected field from a Page 17 single well. Figure provided by Laboratory of I Provencio, Univ Virginia. mu p75-SAP TARGET: mouse NGFr a chemical conjugate of the affinity-purified rabbit polyclonal antibody p75 NTR (Cat. #AB-N01 AP ) and the ribosome-inactivating protein, saporin Conjugation of a p75 NTR antibody to saporin has produced a cytotoxin that eliminates the CBF neurons, while sparing neighboring neurons that express GAD, calbindin and parvalbumin. This molecule eliminates cholinergic neurons in the basal forebrain of mice. Drastically increased AT8-positive neurons after immunolesioning of basal forebrain cholinergic neurons (BFCN) with mu p75-SAp. Left panel, white arrows : Cortical pyramidal neurons of non- injected Tg brain showing occasional punctate immunoreactivity for AT-8 (a marker protein for tangles) indicating “subtle” tau phosphorylation in untreated Tg brain. Right panel, white arrows : Cortical pyramidal neurons of mu p75-SAp-injected Tg brain showing strong immunoreactivity for AT-8 (a marker protein for tangles) indicating the presence of “tangle-bearing” neurons in immunotoxin-injected Tg brain. Figure provided by Neelima Chauhan. mu p75-SAP Kit: conjugate and controls (conjugate alone) (saporin, antibody, control conjugate) related products: Cat # Units Cat # Units affinity-purified anti-NGFr (Cat. #AB- IT-16-50 50 micrograms KIT-16-50 50 micrograms N01 Ap ), rabbit-IgG-SAp (Cat. #IT-35), IT-16-100 100 micrograms KIT-16-100 100 micrograms 192-IgG-SAp (Cat. #IT-01), ME20.4- SAp (Cat. #IT-15) IT-16-250 250 micrograms KIT-16-250 250 micrograms

NPY-SAP TARGET: neuropeptide Y receptor a chemical conjugate of neuropeptide Y (NPY) and the ribosome-inactivating protein, saporin Neuropeptide Y (NPY) receptor is the most abundant neuropeptide in the brain and is involved in many processes from prenatal to mature animals. It promotes the proliferation of postnatal neuronal precursor cells and exhibits a diverse range of important physiologic activities, including effects on psychomotor activity, food intake, regulation of central endocrine secretion, and potent vasoactive effects on the cardiovascular system. NPY-SAP specifically eliminates cells expressing the NPY receptor.

NPY-SAP Kit: conjugate and controls

, (conjugate alone) (saporin, control conjugate) g w n i a k p a Cat # Units Cat # Units d h n s i

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g IT-28-25 25 micrograms KIT-28-25 25 micrograms e n i h t k

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i IT-28-100 100 micrograms KIT-28-100 100 micrograms o l

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i IT-28-250 250 micrograms KIT-28-250 250 micrograms s t i t b n

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C related products: Blank-SAp (Cat. #IT-21), Leptin-SAp (Cat. #IT-47), Oxytocin-SAp (Cat. #IT-46)

Adult, male, Sprague-Dawley rats were tested for 5 days on the 44°C hotplate. Then, toxins or saline vehicle were injected into the lumbar subarachnoid space under anesthesia. Beginning the day after injection, the rats were tested on the hotplate at 44°, 47° and 52° C. At the end of the second week, formalin (25 ul, 5%) was injected into the dorsal surface of one hindpaw of each rat. Intrathecal NpY-SAp altered behavior in the formalin test – rats held the injected hindpaw close to the body (guarded) but did not shake, lick or bite the paw. Figure provided by RG Wiley and RH Kline Page 18 OX7-SAP TARGET: rat / mouse / rabbit / guinea pig Thy-1.1 a chemical conjugate of the mouse monoclonal antibody to OX7 (Cat. #AB-N08) and the ribosome- inactivating protein, saporin Administration of OX7-SAP results in elimination of cells that express Thy 1.1 (or CD90) in rat, mouse, rabbit, or guinea pig. An excellent tool for specific targeting of neuronal projections through suicide transport. OX7-SAP (conjugate alone) Cat # Units IT-02-25 25 micrograms IT-02-100 100 micrograms IT-02-250 250 micrograms

Kit: conjugate and controls (saporin, antibody, control conjugate) Cat # Units KIT-02-25 25 micrograms KIT-02-100 100 micrograms KIT-02-250 250 micrograms pC12 cells are plated at 5000 cells/well and incubated overnight. OX7-SAp is added related products: in 10 µl volumes and the plates are incubated 72 hours. pMS/MTS developing OX7 antibody (Cat. #AB-N08), reagent is added and the plates are incubated 1-2 hours, then read at 490 nm in a Mouse IgG-SAp (Cat. #IT-18) plate reader. Data analysis was done by pRISM (Graphpad).

Oxytocin-SAP TARGET: oxytocin receptor a chemical conjugate of native oxytocin peptide and the ribosome-inactivating protein, saporin Oxytocin is a nine amino acid peptide with a structure similar to vasopressin, and is a hormone released by the posterior pituitary. Peripheral activity of oxytocin is linked primarily to lactation and labor-related uterine contractions. Within the brain, oxytocin receptor-positive neurons have been studied with regard to their sensitivity to leptin and involvement in satiety.

Oxytocin-SAP Kit: conjugate and control related products: (conjugate alone) (saporin) Blank-SAp (Cat. #IT-21), Cat # Units Cat # Units Leptin-SAp (Cat. #IT-47), NpY-SAp IT-46-25 25 micrograms KIT-46-25 25 micrograms (Cat. #IT-28) IT-46-100 100 micrograms KIT-46-100 100 micrograms IT-46-250 250 micrograms KIT-46-250 250 micrograms

Page 19 SSP-SAP TARGET: substance P ( NK-1 ) receptor a chemical conjugate of a peptidase-resistant [Sar 9 , Met(O 2)11 ] analog of Substance P and the ribosome- inactivating protein, saporin SSP-SAP is a conjugation of saporin and SSP, the Sar 9, Met(O 2)11 analog of Substance P. These two amino acid replacements are at two sites of digestion by tissue proteases (there is a third that is still in the analog, so it does eventually get degraded). Since the targeting agent is, of course, necessary for the cytotoxic activity, SSP-SAP will diffuse farther, and thus hit more target cells. This specific analog of SP-saporin resists peptidase digestion, allowing a greater diffusion from the injection site before its metabolism. SSP-SAP eliminates cells expressing the Substance P (NK-1) receptor. All other cells are left untouched, even when they are the predominant cell type.

KNRK NK-1r cells are SSP-SAP plated at 2500 cells/well (conjugate alone) and incubated overnight. SSp-SAp is added in 10 µl Cat # Units volumes and the plates are IT-11-25 25 micrograms incubated 72 hours. IT-11-100 100 micrograms pMS/MTS developing reagent is added and the plates are incubated 1-2 Kit: conjugate and controls hours, then read at 490 nm (saporin, control conjugate) in a plate reader. Data analysis was done by Cat # Units pRISM (Graphpad). KIT-11-25 25 micrograms Limited Label License KIT-11-100 100 micrograms This product is the subject of claims in a U.S. patent entitled "Substance P-Saporin (SP-SAP) Conjugates and Methods of Use Thereof" (6,063,758), owned by Advanced Targeting Systems, Inc. Purchase of this product conveys to the buyer only the non-transferable right under this patent to use the product in research conducted by the buyer. related product: Blank-SAp (Cat. #IT-21)

SP-CTA TARGET: substance P receptor a chemical conjugate of the neuropeptide substance P and the catalytic A subunit of cholera toxin Targeted toxins are powerful and specific lesioning agents used in the technique known as Molecular Neurosurgery. As an alternative, the ability to stimulate neurons selectively can be just as powerful a tool. The catalytic A subunit of cholera toxin (CTA) is bound to a targeting agent (antibody, growth factor, peptide, ligand, cytokine). The targeted conjugate is administered to the cells ( in vitro or in vivo ). The targeting agent seeks out and binds to its target on the cell surface. The conjugate is internalized, CTA breaks away from the targeting agent, and activates the cAMP pathway within the cells by ribosylating adenylate cyclase. Cells which do not have the cell surface marker are not affected. SP-CTA stimulates cells expressing the substance P receptor. Immunohistochemical localization of Sp-CTA uptake in the dorsal horn of the cervical spinal cord. Sp-CTA (10 SP-CTA µg) was injected intracisternally into rats via a (conjugate alone) percutaneous puncture under isoflurane anesthesia. One hour later the animals were euthanized and Cat # Units sections (20 µ) of the brain stem and cervical spinal cord were prepared for immunohistochemistry. IT-39-25 25 micrograms Immunofluorescence co-labeling for the NK1 receptor IT-39-100 100 micrograms (Green) and for CTA (Red) was performed. CTA was IT-39-250 250 micrograms found only in neurons co-labeled with NK1 receptor. Note that at this time point a significant amount of CTA is still on the surface of the cord. Figure provided by R. M. Caudle. Page 20 Secondary Conjugates

Secondary conjugates are conjugations of a secondary antibody to the ribosome-inactivating protein, saporin (from the seeds of the plant, Saponaria officinalis ). The secondary conjugate uses the secondary antibody to "piggyback" onto YOUR primary antibody in order to evaluate the ability of the primary antibody to internalize. Once the conjugate is internalized, saporin breaks away from the targeting agent and inactivates the ribosomes, which causes protein synthesis inhibition and eventual cell death after 2-4 days. Potency may vary according to the specificity and affinity of YOUR antibody to ITS receptor. Secondary conjugates are most effective in determining specificity of your antibody and suitability for conjugation as a primary immunotoxin. When the in vitro results confirm the desired specificity, it is recommended that you order a custom conjugation of your antibody to saporin.

Anti-M-ZAP PRIMARY: mouse monoclonal IgM a chemical conjugate of affinity-purified goat anti-mouse IgM and the ribosome-inactivating protein, saporin Anti-M-ZAP uses your primary mouse monoclonal IgM antibody to target and eliminate cells that recognize your primary antibody. This reagent can be utilized for screening mouse IgM antibodies for internalization and/or their suitability to make potent immunotoxins.

Anti-M-ZAP Kit: conjugate and control (conjugate alone) (control conjugate) Cat # Units Cat # Units related products: IT-30-25 25 micrograms KIT-30-25 25 micrograms Goat IgG-SAp (Cat. #IT-19), Mouse IgM-SAp (Cat. #IT-41), IT-30-100 100 micrograms KIT-30-100 100 micrograms Custom Conjugations IT-30-250 250 micrograms KIT-30-250 250 micrograms

Page 21 Fab-ZAP PRIMARY: mouse monoclonal IgG, monovalent a chemical conjugate of goat anti-mouse monovalent antibody and the ribosome-inactivating protein, saporin Fab-ZAP uses your primary mouse monoclonal IgG antibody to target and eliminate cells that recognize your primary antibody. Fab-ZAP is made with a monovalent secondary antibody eliminating the possibility of cap formation, while preserving all the qualities that make an effective in vitro diagnostic tool. It also has an improved ED 50 when directly compared to Mab-ZAP in a cytotoxicity assay. This reagent can be utilized for screening mouse IgG antibodies for internalization and/or their suitability to make potent immunotoxins.

Fab-ZAP versions for other species Fab-ZAP (conjugate alone) are currently being produced -- visit Cat # Units our website for the IT-48-25 25 micrograms latest info. IT-48-100 100 micrograms IT-48-250 250 micrograms pC12 cells were plated at 5000 cells/90 μl/well and incubated Kit: conjugate and control overnight. Saporin, and OX7- (control conjugate) SAp dilutions were made in cell media, and 10 μl was added to Cat # Units each well. OX7 antibody KIT-48-25 25 micrograms (AB-N08) was diluted in cell media containing, at a final concentration, either 100 ng/10 μl Mab-ZAp or 45 ng/10 µl Fab-ZAp, and 10 μl was added to each well. The plates were KIT-48-100 100 micrograms incubated 72 hr. The medium was dumped off of the plate, and the cells were fixed with KIT-48-250 250 micrograms ice-cold 10% TCA for 1 hr at 4°C. The plate was washed 3 times with tap water and allowed to air dry. 50 µl of 0.4% sulfarhodamine B/1% acetic acid was added to each well related products: and the plate was incubated for 30 min at room temperature. The plate was washed 3 Goat IgG-SAp (Cat. #IT-19), times with 1% acetic acid and allowed to air dry. The dye was solubilized with 100 µl of 10 Mab-ZAp (Cat. #IT-04), mM unbuffered tris base per well, with 5 min of gentle shaking. The plate was read at 564 nm, and data analysis done with prism software (Graphpad, San Diego). Custom Conjugations

Goat-ZAP PRIMARY: goat monoclonal IgG a chemical conjugate of affinity-purified rabbit anti-goat IgG and the ribosome-inactivating protein, saporin Goat-ZAP uses your primary goat monoclonal IgG antibody to target and eliminate cells that recognize your primary antibody. This reagent can be utilized for screening goat IgG antibodies for internalization and/or their suitability to make potent immunotoxins. 3T3 cells were plated at 1000 cells/90 µl/well in a 96-well Goat-ZAP (conjugate alone) plate and incubated overnight. Cat # Units Saporin dilutions were made in cell media, and 10 µl was IT-36-25 25 micrograms added to each well. EGFr IT-36-100 100 micrograms antibody was diluted in cell media containing, at a final IT-36-250 250 micrograms concentration, 100 ng/10 µl of Goat-ZAp, and 10 µl was Kit: conjugate and control added to each well. The (control conjugate) plates were incubated 72 hours and developed with Cat # Units MTS/pMS KIT-36-25 25 micrograms Data was analyzed by prism (Graphpad). KIT-36-100 100 micrograms related products: rabbit IgG-SAp (Cat. #IT-35), Custom Conjugations KIT-36-250 250 micrograms

Page 22 Hug-M-ZAP PRIMARY: human monoclonal IgM a chemical conjugate of affinity-purified goat anti-human IgM and the ribosome-inactivating protein, saporin Hug-M-ZAP uses your primary human monoclonal IgM antibody to target and eliminate cells that recognize your primary antibody. This reagent can be utilized for screening human IgM antibodies for internalization and/or their suitability to make potent immunotoxins.

hug-M-ZAP Kit: conjugate and control (conjugate alone) (control conjugate) Cat # Units Cat # Units IT-43-25 25 micrograms KIT-43-25 25 micrograms IT-43-100 100 micrograms KIT-43-100 100 micrograms IT-43-250 250 micrograms KIT-43-250 250 micrograms related products: Goat IgG-SAp (Cat. #IT-19), Custom Conjugations

Hum-ZAP PRIMARY: human monoclonal IgG a chemical conjugate of affinity-purified goat anti-human IgG and the ribosome-inactivating protein, saporin Hum-ZAP uses your primary human monoclonal IgG antibody to target and eliminate cells that recognize your primary antibody. It can be utilized for screening human IgG antibodies for internalization and/or their suitability to make potent immunotoxins. hum-ZAP (conjugate alone) Cat # Units IT-22-25 25 micrograms IT-22-100 100 micrograms IT-22-250 250 micrograms

Kit: conjugate and control (control conjugate) Cat # Units KIT-22-25 25 micrograms KIT-22-100 100 micrograms KIT-22-250 250 micrograms pC12 cells are plated at 1000 cells/90 microliters/well and incubated overnight. OX7- SAp dilutions are made into cell media and 10 microliters is added to each well. OX7 is diluted into cell media containing 100 ng/10 microliters Hum-ZAp and 10 microliters related products: is added to each well. The plates are incubated 72 hours. pMS/MTS developing Goat IgG-SAp (Cat. #IT-19), reagent is added and the plates are incubated 1-2 hours, then read at 490 nm. Custom Conjugations Data is analyzed by prism (Graphpad).

Please visit http://www.atsbio.com/catalog/protocols/ for a comprehensive set of protocols for use with Secondary Conjugates.

Page 23 Mab-ZAP PRIMARY: mouse monoclonal IgG a chemical conjugate of affinity-purified goat anti-mouse IgG and the ribosome-inactivating protein, saporin Mab-ZAP uses your primary mouse monoclonal IgG antibody to target and eliminate cells that recognize your primary antibody. This reagent can be utilized for screening mouse IgG antibodies for internalization and/or their suitability to make potent immunotoxins. pC12 cells were plated at 5000 Mab-ZAP cells/90 µl/well and incubated overnight. Saporin and OX7-SAp (conjugate alone) dilutions were made in cell media, Cat # Units and 10 µl was added to each well. OX7 antibody (AB-N08) was diluted IT-04-25 25 micrograms in cell media containing, at a final IT-04-100 100 micrograms concentration, 100 ng/10 µl Mab- IT-04-250 250 micrograms ZAp, and 10 µl was added to each well. The plates were incubated 72 Kit: conjugate and control hours and developed with MTS/pMS. (control conjugate) Data analyzed by prism (Graphpad). Cat # Units KIT-04-25 25 micrograms KIT-04-100 100 micrograms KIT-04-250 250 micrograms related products: Goat IgG-SAp (Cat. #IT-19), Custom Conjugations

Rab-ZAP PRIMARY: rabbit polyclonal IgG a chemical conjugate of affinity-purified goat anti-rabbit IgG and the ribosome-inactivating protein, saporin Rab-ZAP uses your primary rabbit polyclonal IgG antibody to target and eliminate cells that recognize your primary antibody. This reagent can be utilized for screening rabbit IgG antibodies for internalization and/or their suitability to make potent immunotoxins.

Rab-ZAP (conjugate alone) Cat # Units IT-05-25 25 micrograms IT-05-100 100 micrograms IT-05-250 250 micrograms

Kit: conjugate and control Activity of rab-ZAp (control conjugate) complexed with primary antibody to cells expressing Cat # Units primary antibody's antigen. KIT-05-25 25 micrograms In this experiment, cells KIT-05-100 100 micrograms expressing the antigen were challenged with a primary KIT-05-250 250 micrograms immunotoxin (mu p75-SAp, Cat. #IT-16). Cells were also challenged with the primary related products: affinity-purified polyclonal antibody (AB-N01ap) at the same concentrations and pre- incubated with Rab-ZAp (Lot #69-30) at 200 ng per well. Goat IgG-SAp (Cat. #IT-19) Both primary immunotoxin and Rab-ZAp have similar cytotoxicity to the target cells. Rab- Custom Conjugations ZAp alone at 200 ng per well has no effect, nor does the antibody alone at 10 nM. Page 24 Rat-ZAP PRIMARY: rat monoclonal IgG a chemical conjugate of affinity-purified goat anti-rat IgG and the ribosome-inactivating protein, saporin Rat-ZAP uses your primary rat monoclonal IgG antibody to target and eliminate cells that recognize your primary antibody. This reagent can be utilized for screening rat IgG antibodies for internalization and/or their suitability to make potent immunotoxins. Rat-ZAP (conjugate alone) Cat # Units IT-26-25 25 micrograms IT-26-100 100 micrograms IT-26-250 250 micrograms Kit: conjugate and control (control conjugate) Cat # Units KIT-26-25 25 micrograms WEHI-274.1 cells, mouse monocytes, were plated at 1000 cells/90 µl/well in a KIT-26-100 100 micrograms 96-well plate and incubated overnight. Saporin and saporin conjugated to a rat KIT-26-250 250 micrograms monoclonal against human Mac-1 (CD11b) (Cat. #AB-N05) dilutions were made in cell media, and 10 µl was added to each well. Rat anti-Mac-1 human related products: (CD11b) was diluted in cell media containing, at a final concentration, 50 ng/10 Goat IgG-SAp (Cat. #IT-19), µl of Rat-ZAp, and 10 µl was added to each well. The plates were incubated 72 hours and developed with MTS/pMS. Data was analyzed by prism (Graphpad). Custom Conjugations

Custom Conjugates

Custom Conjugates are powerful tools that specifically destroy targeted cell types. This technique has important research applications in determining the function or contribution of the targeted cells in a biological system or for the removal of interfering cell types. Through the use of custom conjugates, you can eliminate any cell type. Requirements for Successful Targeting • A cell surface marker. • A molecule, such as an antibody or a ligand, that binds to that marker. Your targeting agent is conjugated to Saporin, a highly active and potent ribosome-inactivating protein.

Getting Started Step 1: Select your targeting agent. Step 2: Use the appropriate Secondary Conjugate to screen your targeting agent for specificity and internalization. Step 3: Call ATS toll-free (877) 889-2288 to discuss your targeting project. All discussions and services can be covered with a confidentiality agreement. Step 4: Prepare for stunning, powerful research results!

Page 25 Streptavidin-ZAP PRIMARY: biotinylated material a chemical conjugate of streptavidin and the ribosome-inactivating protein, saporin Streptavidin is isolated from Streptomyces avidinii and has a molecular weight of 53 kDa in its recombinant form. The streptavidin in Streptavidin-ZAP has no carbohydrate group and a neutral isoelectric point, therefore reducing nonspecific binding levels as compared to avidin. Streptavidin is less water soluble than avidin . Streptavidin is also a tetrameric protein, with each subunit able to bind a single biotin molecule. Biotin, a 244 dalton vitamin found in tissue and blood, binds with high affinity to streptavidin. In fact, the streptavidin- biotin interaction is the strongest known noncovalent biological interaction (Ka = 10 15 M-1 ) between protein and ligand. The bond formation between streptavidin and biotin is rapid and essentially non-reversible, unaffected by most extremes of pH, organic solvents, and denaturing reagents. Extensive chemical modification has little effect on the activity of the protein. A variety of molecules, including lectins, proteins, and antibodies, can be biotinylated and reacted with streptavidin-labeled probes or other detection reagents for use in biological assays. Streptavidin-ZAP (conjugate alone) Cat # Units IT-27-25 25 micrograms IT-27-100 100 micrograms IT-27-250 250 micrograms

Kit: conjugate and control (saporin) Cat # Units KIT-27-25 25 micrograms KIT-27-100 100 micrograms KNRK cells are plated at 2500 cells/well and incubated overnight. Streptavidin- KIT-27-250 250 micrograms ZAp is premixed with Biotinylated-IB4 in equimolar concentrations. Saporin, IB4-SAp, and the Streptavidin-ZAp + Biotinylated-IB4 mixture are then added in 10-µl volumes and the plates are incubated 72 hours. pMS/MTS developing reagent is added and the plates are incubated 15-30 minutes, then read at 490 nm in a plate reader. Data analysis was done by pRISM (Graphpad).

Biotinylation Service A variety of molecules, including lectins, proteins, and antibodies, can be biotinylated and reacted with streptavidin-labeled probes or other detection reagents for use in biological assays. Using streptavidin- ZAP and biotinylated targeting agents, specific cytotoxins can be created JUST BY MIXING! Step 1: Send ATS your targeting agent (antibody, lectin, etc.).

Step 2: ATS biotinylates your targeting agent and returns it to you with streptavidin-ZAP.

Step 3: You mix together your biotinylated targeting agent and streptavidin-ZAP to specifically eliminate cells that recognize and internalize your targeting agent.

Page 26 Control Conjugates

One of the most important features of the Advanced Targeting Systems product line is the availability of control toxins that allow the researcher to fully evaluate results of the treatment of cells or animals with targeted toxins. For instance, anti-DBH-SAP is targeted with a mouse monoclonal antibody. Its control partner is mouse IgG-SAP, that is, mouse IgG that has no targeting properties. The difference in effect between these two shows the difference between targeted toxins and non-targeted. Similarly, Blank-SAP is the appropriate control molecule for the peptide ligand-targeted toxins. Blank-SAP behaves as its name implies; you’re shooting blanks because the peptide sequence has no receptor, but the residues in the blank peptide contain the usual amino acids that are often found in ligand sequences. These materials are provided at a nominal charge in targeted toxin kits. They are a great improvement, we believe, over using just plain saporin as control, or even saporin and its targeting vehicle added together, but not conjugated.

Blank-SAP CONTROL FOR: peptide conjugates a chemical conjugate between a non-targeted peptide and the ribosome-inactivating protein, saporin This molecule is the perfect control for use with peptide conjugates such as: SSP-SAP, orexin-SAP, dermorphin-SAP (MOR-SAP), CRF-SAP, NPY-SAP, CCK-SAP, Bombesin-SAP, Oxytocin-SAP and Galanin- SAP. The sequence of the non-targeted peptide of Blank-SAP is an 11-amino acid, randomly mixed version of the sequence of melanocyte-stimulating hormone, with amino acid residues that are typical of peptides that bind to G-protein-coupled receptors. Examination of the peptide sequence using NCBI/BLAST reveals no homologous sequences. Thus, Blank-SAP can be used as control for any non-specific effects of the toxin and provides a definitive baseline for determining the effects of a targeted peptide conjugate . Blank-SAP (conjugate alone) Cat # Units IT-21-25 25 micrograms IT-21-100 100 micrograms IT-21-250 250 micrograms

KNRK cells expressing the substance p receptor (NK-1r) were plated at 2500 cells/well in a 96-well plate and incubated overnight at 37°C. The following morning, Sp-SAp, unconjugated saporin, or Blank-SAp was added. plates were incubated for 72 hours before being developed with MTS/pMS (promega). The ED 50 's show that Blank-SAp has almost no activity in the tested concentration range. Data analysis was done by Page 27 pRISM (Graphpad). Goat IgG-SAP CONTROL FOR: secondary conjugates a chemical conjugate of pre-immune goat IgG antibody and the ribosome-inactivating protein, saporin This molecule is the perfect control for use with the secondary conjugates: Mab-ZAP (goat anti- mouse IgG conjugated to saporin), Rab-ZAP (goat anti-rabbit IgG conjugated to saporin), Hum- ZAP (goat anti-human IgG conjugated to saporin), Rat-ZAP (goat anti-rat IgG conjugated to saporin), Hug-M-ZAP (goat anti-human IgM conjugated to saporin), and Anti-M-ZAP (goat anti-mouse IgM conjugated to saporin). The secondary conjugates are used with a primary antibody to determine if the primary antibody can internalize saporin and would, therefore, be suitable for conjugation as a primary immunotoxin. Goat IgG-SAP, used in place of the secondary conjugate, will give a definitive baseline for comparison of the activity of the primary antibody to internalize. The accompanying figure shows that, while the primary, in this case OX7, is able to internalize the secondary conjugate, the goat IgG-SAP is not.

Cytotoxicity of second immunotoxin and control Goat IgG-SAP (conjugate alone) immunotoxin Goat IgG-SAp to pC12 cells. Cat # Units Concentration of samples is above the bars for each. Samples are added to pC12 cells (5000 per well, put in culture the night IT-19-25 25 micrograms before). Mab-ZAp and Goat IgG-SAp are at 50 ng/well, while the primary IT-19-100 100 micrograms antibody is at 100 pM. The "primary" immunotoxin OX7-SAp (Cat. #IT-02) removes greater IT-19-250 250 micrograms than 65% of the cells at 100 pM, and the second immunotoxin Mab-ZAp incubated with the OX7 antibody (Cat. #AB-N08) removes about 50%, while the control Goat IgG-SAp incubated with the OX7 antibody is not significantly different than untreated controls.

Human IgG-SAP CONTROL FOR: human monoclonal conjugates a chemical conjugate of pre-immune human IgG antibody and the ribosome-inactivating protein, saporin This product serves as a control for the human IgG-containing immunolesioning agents. It is the same molecular weight, consists of comparable materials (saporin and a human IgG) and is synthesized with the same protocol as the targeted immunotoxins. The difference is the cell-specific antibodies are replaced with "blanks," antibodies that have no specificity, and no ability to target cells. pC12 cells were plated at 5,000 cells/90 μl/well and incubated overnight. Saporin, OX7-SAp, and Human IgG-SAp dilutions were made in cell media, and 10 μl was added to each well. OX7 antibody (AB- N08) was diluted in cell media containing, at a final concentration, 100 ng/10 μl Hum-ZAp, and 10 μl was added to each well. The plates were incubated 72 hours. The medium was dumped off human IgG-SAP of the plate, and the cells were fixed (conjugate alone) with ice-cold 10% TCA for 1 hour at 4°C. The plate was washed 3 times with tap Cat # Units water and allowed to air dry. 50 µl of IT-49-25 25 micrograms 0.4% sulfarhodamine B/1% acetic acid was added to each well and the plate was incubated for 30 minutes at room IT-49-100 100 micrograms temperature. The plate was washed 3 times with 1% acetic acid and allowed to IT-49-250 250 micrograms air dry. The dye was solubilized with 100 µl of 10 mM unbuffered tris base per well, with 5 minutes of gentle shaking. The plate was read at 564 nm, and data analysis was done with prism software (Graphpad, San Diego). Page 28 Mouse IgG-SAP CONTROL FOR: mouse monoclonal conjugates a chemical conjugate of pre-immune mouse IgG antibody and the ribosome-inactivating protein, saporin This product serves as a control for the immunotoxins that use a mouse monoclonal: 192-IgG-SAP, OX7-SAP, Anti-DBH-SAP, ME20.4-SAP, Anti-SERT-SAP, Anti-CD22-SAP, Anti-human CD25-SAP, Mac-1-SAP (rat- specific). It is the same molecular weight, consists of comparable materials (saporin and a mouse IgG) and is synthesized with the same protocol as the targeted immunotoxins. The difference is the cell-specific antibodies are replaced with "blanks," antibodies that have no specificity, and no ability to target cells.

Mouse IgG-SAP (conjugate alone) Cat # Units IT-18-25 25 micrograms IT-18-100 100 micrograms IT-18-250 250 micrograms pC12 cells, a rat tumor cell line that expresses the Thy 1 receptor, were plated at 1000 cells per well and allowed to acclimatize overnight. The cells were exposed to the various reagents at the indicated concentrations for 72 hours. MTS/pMS (promega) mixture was added and plates were read on a Molecular Diagnostics Spectramax plate reader with SoftMax software. Data was analyzed by prism 4.0 software.

Mouse IgM-SAP CONTROL FOR: mouse monoclonal conjugates a chemical conjugate of pre-immune mouse IgM antibody and the ribosome-inactivating protein, saporin This product serves as a control for mouse IgM-containing immunolesioning agents. It is the same molecular weight, consists of comparable materials (saporin and normal mouse IgM) and is synthesized with the same protocol as the targeted immunotoxins. The cell-specific antibodies are replaced with "blanks," antibodies that have no specificity, and no ability to target cells.

Mouse IgM-SAP (conjugate alone) Cat # Units IT-41-25 25 micrograms IT-41-100 100 micrograms IT-41-250 250 micrograms

Page 29 Rabbit IgG-SAP CONTROL FOR: rabbit polyclonal conjugates a chemical conjugate of pre-immune rabbit IgG antibody and the ribosome-inactivating protein, saporin This product serves as a control for the immunotoxins that use a rabbit polyclonal: mu p75-SAP, GAT1-SAP, Goat-ZAP (rabbit anti-goat IgG conjugated to saporin), and Melanopsin-SAP. It is the same molecular weight, consists of comparable materials (saporin and a rabbit IgG) and is synthesized with the same protocol as the targeted immunotoxins. The difference is the cell-specific antibodies are replaced with "blanks," antibodies that have no specificity, and no ability to target cells. NG6 cells were plated at 1000 cells per well and allowed to acclimate for 15-18 hours. Reagents were added such that the most concentrated dose was 10 nM for AB-N01-SAp, 100 nM for Rabbit IgG-SAp, and 1 µM for Saporin. 1:10 dilutions were made for a total of 8 dilutions at 6 replicates apiece. plates were incubated at 37°C for 72 hours. ED 50 was determined by evaluating the percent of live cells, developed with a MTS/pMS mixture, and comparison to cells in wells that received no treatment. Data was collected on a plate reader and evaluated with prism software (Graphpad).

Rabbit IgG-SAP (conjugate alone) Cat # Units IT-35-25 25 micrograms IT-35-100 100 micrograms IT-35-250 250 micrograms

Rat IgG-SAP CONTROL FOR: rat monoclonal conjugates a chemical conjugate of pre-immune rat IgG antibody and the ribosome-inactivating protein, saporin This product serves as a control for the immunotoxins that use a rat monoclonal: Mac-1-SAP mouse/human, Anti-CD25-SAP mouse, and Anti-DAT-SAP. It is the same molecular weight, consists of comparable materials (saporin and a rat IgG) and is synthesized with the same protocol as the targeted immunotoxins. The difference is the cell-specific antibodies are replaced with "blanks," antibodies that have no specificity, and no ability to target cells. WEHI-274.1 cells, a murine monocytic cell line, were plated at 2500 cells per well in 90 µl of medium. After allowing acclimatization overnight, the cells were exposed to the various reagents at the indicated concentrations for 72 hours. MTS/pMS (promega) was added and after two hours, plates were read at 492 nM on a plate reader. Data were analyzed by prism software (Graphpad).

Rat IgG-SAP (conjugate alone) Cat # Units IT-17-25 25 micrograms IT-17-100 100 micrograms IT-17-250 250 micrograms Page 30 Fluorescent Conjugates

192-IgG Mouse Monoclonal, Alexa488-labeled ...... 25 µg, 100 µg ...... FL-03 192-IgG Mouse Monoclonal, Cy3-labeled ...... 25 µg, 100 µg ...... FL-01 Acetylated Lysine Rabbit Polyclonal, FITC-labeled ...... 100 µg ...... AB-269 Biotin Rabbit Polyclonal, FITC-labeled ...... 100 µg ...... AB-282 CD14 Mouse Monoclonal, FITC-labeled ...... 500 µg ...... AB-411 CD2 Mouse Monoclonal, FITC-labeled ...... 500 µg ...... AB-554 CD21 Mouse Monoclonal, FITC-labeled ...... 500 µg ...... AB-557 CD28 Hamster Monoclonal, FITC-labeled ...... 500 µg ...... AB-571 CD3 Mouse Monoclonal, FITC-labeled ...... 500 µg ...... AB-419 CD4 Mouse Monoclonal, FITC-labeled ...... 500 µg ...... AB-423 CD4 Rat Monoclonal, FITC-labeled ...... 500 µg, 1 mg ...... AB-584 CD40 Mouse Monoclonal, FITC-labeled ...... 500 µg ...... AB-563 CD44 Mouse Monoclonal, FITC-labeled ...... 500 µg ...... AB-425 CD44 Rat Monoclonal, FITC-labeled ...... 500 µg ...... AB-587 CD45 Mouse Monoclonal, FITC-labeled ...... 500 µg ...... AB-560 CD58 Mouse Monoclonal, FITC-labeled ...... 500 µg ...... AB-574 CD8 Mouse Monoclonal, FITC-labeled ...... 500 µg ...... AB-430 (continued on next page) 192-IgG Alexa488-labeled Mouse Monoclonal, Cat. #FL-03 192-IgG Cy3 -labeled Mouse Monoclonal, Cat. #FL-01

C6/9 cells, a rat glioma cell line, were incubated with the fluorescent conjugate for one hour. Cells were run on a C6/9 cells, a rat glioma cell line, were labeled with 192-IgG BD FACScan and data analyzed with CellQuest software. conjugated to Cy3 dye at various concentrations, and allowed to incubate at 4°C for one hour. Unlabeled antibody was used as a Applications include flow cytometry (1 µg/10 6 cells), control. Cells were then washed, and samples analyzed on a BD fluorescence spectroscopy and anisotropy, epifluorescence FACScan. Data was processed using CellQuest software. The microscopy, radioligand competition binding assay, conjugated 192 IgG-Cy3 demonstrated a 43% positive shift qualitative probe of binding to membrane-bound IgG’s and versus the control. the cytoskeleton. Applications include flow cytometry (4 µg/10 6 cells per 200 µl), immunofluorescence, and immunocytochemistry (paraffin; Page 31 10-20 µg/ml TBS). Donkey Anti-Goat IgG FITC-labeled, Cat. #FL-11 Goat Anti-rabbit IgG FITC-labeled, Cat. #FL-04

3T3 cells were labeled with a primary goat IgG and incubated NG3 cells were incubated with an affinity-purified rabbit at 4°C for 1 hour. Cells were washed, then treated with FITC- polyclonal primary antibody for one hour. The cells were then labeled Donkey anti-Goat IgG. Samples were incubated for 30 incubated for 30 minutes with FITC-labeled goat anti-rabbit IgG minutes at 4°C. Cells were analyzed on a BD FACScan and secondary. Sample was read on a FACScan flow cytometer data analyzed with CellQuest software. and data was analyzed with Cell Quest software. Applications include flow cytometry (2 µg/10 6 cells per 200 µl). Applications include flow cytometry (1 µg/10 6 cells per 200 µl).

Goat Anti-Mouse IgG FITC-labeled, Cat. #FL-07 Goat Anti-rat IgG FITC-labeled, Cat. #FL-10

A clone of RBL-2H3 cells, rat basophilic leukemia cells, were Sorted mouse monocyte cells were labeled with Rat anti- incubated with a protein-A purified mouse monoclonal primary Mouse Mac-1 antibody (Cat. #AB-N05) and incubated at 4°C antibody for one hour. The cells were then incubated for 30 for 1 hour. Cells were washed, then treated with FITC-labeled minutes with FITC-labeled goat anti-mouse IgG secondary. Goat anti-Rat IgG. Samples were incubated for 30 minutes at Sample was read on a FACScan flow cytometer and data was 4°C. Cells were analyzed on a BD FACScan and data analyzed with Cell Quest software. analyzed with CellQuest software. Applications include flow cytometry (1 µg/10 6 cells per 200 µl). Applications include flow cytometry (1 µg/10 6 cells per 200 µl).

CD8 Rat Monoclonal, FITC-labeled ...... 500 µg ...... AB-577 CD86 Rat Monoclonal, FITC-labeled ...... 500 µg ...... AB-580 Donkey Anti-Goat IgG, FITC-labeled ...... 500 µg ...... FL-11 G CSF Mouse Monoclonal, FITC-labeled ...... 500 µg ...... AB-455 Goat Anti-Mouse IgG, FITC-labeled ...... 500 µg ...... FL-07 Goat Anti-Rabbit IgG, FITC-labeled ...... 500 µg ...... FL-04 Goat Anti-Rat IgG, FITC-labeled ...... 500 µg ...... FL-10 (continued on next page) Custom Fluorescent Labeling Do you have an antibody you would like to have labeled? Email ATS ([email protected]) or call toll-free (877) 889-2288 to discuss your project. All discussions and services can be covered with a confidentiality agreement. Page 32 NGFr Alexa488-labeled Ap rabbit polyclonal, Cat. #FL-09 NGFr Cy3 -labeled Ap rabbit polyclonal, Cat. #FL-05

NG6 cells, a clone of the Rat-Mouse hybrid cell line NG108, were treated with either affinity purified Anti-NGFr (Cat. #AB- NG3 cells, a rat-mouse hybrid neuroblastoma cell line, were N01ap), or with Alexa488-labeled Anti-NGFr, at the dosage incubated with anti-NGFr antibody or conjugate and incubated listed. Cells were incubated for one hour at 4°C, then washed at 4°C. Cells were analyzed by flow cytometry on a BD with pBS/2%FBS. FACScan, and data produced using CellQuest software. A Samples were read on a BD FACScan and data processed concentration of 4 µg of conjugate per one million cells with CellQuest software. provided a 33% shift compared to the antibody alone. 6 Applications include flow cytometry (1 µg/10 6 cells per 200 µl). Applications include flow cytometry (4 µg/10 cells per 200 µl).

Interleukin-1 beta Mouse Monoclonal, FITC-labeled ...... 500 µg ...... AB-506 Methylated Lysine Rabbit Polyclonal, FITC-labeled ...... 100 µg ...... AB-271 MHC Class I (H-2K) Mouse Monoclonal, FITC-labeled ...... 500 µg ...... AB-565 MHC Class II (I-A) Mouse Monoclonal, FITC-labeled ...... 500 µg ...... AB-568 NGFr (mu p75) Rabbit Polyclonal, Alexa488-labeled affinity-purified ...... 25 µg, 100 µg ...... FL-09 NGFr (mu p75) Rabbit Polyclonal, Cy3-labeled affinity-purified ...... 25 µg, 100 µg ...... FL-05 NGFr (mu p75) Rabbit Polyclonal, Cy5-labeled affinity-purified ...... 25 µg, 100 µg ...... FL-06 Rabbit anti-Goat IgG, FITC-labeled ...... 1 mg ...... AB-324 Rabbit anti-Human IgG, FITC-labeled ...... 1 mg ...... AB-327 Rabbit anti-Mouse IgG, FITC-labeled ...... 1 mg ...... AB-330 Saporin Goat Polyclonal, FITC-labeled affinity-purified ...... 25 µg, 100 µg ...... FL-02 Tri-methyl Lysine Rabbit Polyclonal, FITC-labeled ...... 100 µg ...... AB-272 Vimentin Mouse Monoclonal, FITC-labeled ...... 500 µg, 1 mg ...... AB-552

Saporin FITC-labeled Ap Goat polyclonal, Cat. #FL-02

Cytometry Research was established to serve the scientific community as a contract flow cytometry service. Call now or visit us online to schedule an appointment. (858) 642-1988 telephone • (877) 889-2288 tollfree www.CytometryRes.com

Ship your samples to us using an overnight service.

C6 cells were fixed and incubated with 100 nM 192-IgG- Provide a protocol for cell preparation if you want us to SAp for one hour. After washing, cells were incubated stain, fix, or otherwise process your samples. with FITC-labeled Anti-SAp at 1 µg/ml for 30 minutes. Your data will be sent to you via email within one Samples were run on a FACSCAN (Becton Dickinson). Data analysis was performed using CellQuest. business day of receipt of samples. Applications include flow cytometry (2 µg/10 6 cells per Download a Sample Shipping Checklist at: 200 µl). http://www.cytometryres.com/forms/shipping.html

Page 33 Antibodies

This is an alphabetical listing of our antibodies. More information including data sheets and references can be found on our website at www.ATSbio.com. Antibodies marked with an asterisk (*) are also available as a targeted toxin. Antibodies marked with a caret (^) also have a peptide or antigen available.

1,3 Butadiene Rabbit Polyclonal ...... 50 µl ...... AB-T102 192-IgG Mouse Monoclonal, Alexa488-labeled ...... 25 µg, 100 µg ...... FL-03 192-IgG Mouse Monoclonal, Cy3-labeled ...... 25 µg, 100 µg ...... FL-01 3-Hydroxykynurenine Rabbit Polyclonal ...... 50 µl ...... AB-T172 4,5-Dihydroxytryptamine Rabbit Polyclonal ...... 50 µl ...... AB-T081 5-Aminolevulinic Acid Rabbit Polyclonal ...... 50 µl ...... AB-T087 5-Hydroxytryptamine (Serotonin) Rabbit Polyclonal ...... 50 µl ...... AB-T03 5-Hydroxytryptophan Rabbit Polyclonal ...... 50 µl ...... AB-T09 5-Hydroxytryptophol Rabbit Polyclonal ...... 50 µl ...... AB-T082 5-Methoxytryptamine Rabbit Polyclonal ...... 50 µl ...... AB-T078 5-Methoxytryptophan Rabbit Polyclonal ...... 50 µl ...... AB-T080 5,6-Dihydroxytryptamine Rabbit Polyclonal ...... 50 µl ...... AB-T105 5,7-Dihydroxytryptamine Rabbit Polyclonal . . . . . 50 µl ...... AB-T106 6-His Mouse Monoclonal 6-His Mouse Monoclonal ...... 100 µg ...... AB-213 Cat. #AB-20 6-Hydroxydopamine Rabbit Polyclonal ...... 50 µl ...... AB-T104 Lane 1: Molecular weight standards 6-Hydroxytryptamine Rabbit Polyclonal ...... 50 µl ...... AB-T103 (SeeBlue) Abscisic acid Rabbit Polyclonal ...... 50 µl ...... AB-T131 Acetyl salicylic acid Rat Polyclonal ...... 50 µl ...... AB-T074 Lane 2: Crude bacterial Acetylated Lysine Rabbit Polyclonal ...... 100 µg ...... AB-202 extract containing a 6- His-tag expressing Acetylated Lysine Rabbit Polyclonal, Biotin-labeled 100 µg ...... AB-201 protein probed with Anti- Acetylated Lysine Rabbit Polyclonal, BSA-labeled . 100 µg ...... AB-270 6-His antibody at a Acetylated Lysine Rabbit Polyclonal, FITC-labeled . 100 µg ...... AB-269 1:5,000 dilution. Band of Acetylated Lysine Rabbit Polyclonal, HRP-labeled . 100 µg ...... AB-296 interest is visualized at Acetylcholine Mouse Monoclonal ...... 50 µl ...... AB-T029 25-28 KDa. Acetylcholine Rabbit Polyclonal ...... 50 µl ...... AB-T02 Acrolein Rabbit Polyclonal ...... 50 µl ...... AB-T091 ACTH Rabbit Polyclonal ...... 100 µl ...... AB-09 actMMP-9 Mouse Monoclonal ...... 1 ml ...... AB-28 Adiponectin Mouse Monoclonal ...... 100 µg ...... AB-401 Adrenaline Rabbit Polyclonal ...... 50 µl ...... AB-T069 Agmatine Rabbit Polyclonal ...... 50 µl ...... AB-T128 AKT1 (Phosphorylated, Ser-473) Rabbit Polyclonal ...... 100 µg ...... AB-204 AKT1 (Phosphorylated, Ser-473) Rabbit Polyclonal, HRP-labeled ...... 100 µg ...... AB-203 AKT1 Polyclonal Antibody ...... 100 µg ...... AB-305 AKT1 Polyclonal Antibody, HRP-labeled ...... 100 µg ...... AB-306 AKT2 (PKB-beta) Rabbit Polyclonal ...... 100 µg ...... AB-205 Alkalescens dispar Rabbit Polyclonal ...... 50 µl ...... AB-T166 Alpha-Tocopherol Acid Succinate Rabbit Polyclonal ...... 50 µl ...... AB-T145 Angiotensin II receptor (AT-1Ar) Rabbit Polyclonal, affinity-purified ...... 50 µg ...... AB-N25AP Angiotensin II receptor (AT-1Br) Rabbit Polyclonal, affinity-purified ...... 50 µg ...... AB-N26AP Page 34 Antibodies (continued) Angiotensin II receptor (AT-1r) Rabbit Polyclonal, affinity-purified ...... 50 µg ...... AB-N27AP Angiotensin II receptor (AT-2r) Rabbit Polyclonal, affinity-purified ...... 50 µg ...... AB-N28AP Anthranilic Acid Rabbit Polyclonal ...... 50 µl ...... AB-T155 Anthrax LF Rabbit Polyclonal ...... 200 µl ...... AB-402 Anthrax PA Rabbit Polyclonal ...... 200 µl ...... AB-403 Anti-Phospho-S6 Peptide Rabbit Polyclonal ...... 100 µg ...... AB-207 Anti-Phospho-S6 Peptide Rabbit Polyclonal, HRP-labeled ...... 100 µg ...... AB-206 Ascorbic acid Rat Polyclonal ...... 50 µl ...... AB-T151 ATP Binding Cassette A1 Protein Mouse Monoclonal ...... 100 µg ...... AB-208 Azelaic acid Rabbit Polyclonal ...... 50 µl ...... AB-T093 B-Actin Rabbit Polyclonal ...... 200 µg ...... AB-273 B-Tubulin Rabbit Polyclonal ...... 200 µg ...... AB-274 B220 (CD45R) Rat Monoclonal ...... 500 µg ...... AB-404 BAM12P Rabbit Polyclonal ...... 100 µl ...... AB-13 BAM22P Rabbit Polyclonal ...... 100 µl ...... AB-12 Basigin Mouse Monoclonal ...... 50 µg ...... AB-42 Benzo(a)pyrene (BAP) Rabbit Polyclonal ...... 50 µl ...... AB-T137 Beta-alanine Rabbit Polyclonal ...... 50 µl ...... AB-T033 Biotin Rabbit Polyclonal ...... 1 mg ...... AB-280 Biotin Rabbit Polyclonal, BSA-labeled ...... 100 µg ...... AB-283 Biotin Rabbit Polyclonal, FITC-labeled ...... 100 µg ...... AB-282 Biotin Rabbit Polyclonal, HRP-labeled ...... 100 µg ...... AB-281 Bone Morphogenetic protein-2 Mouse Monoclonal ...... 100 µg ...... AB-405 Brain-Derived Neurotrophic Factor Mouse Monoclonal ...... 500 µg, 1 mg ...... AB-406 c-Myc Mouse Monoclonal ...... 500 µg, 1 mg ...... AB-407 Capric acid Rat Polyclonal ...... 50 µl ...... AB-T085 Caproic acid Rat Polyclonal ...... 50 µl ...... AB-T083 Caprylic acid Rat Polyclonal ...... 50 µl ...... AB-T084 Carnosine Rabbit Polyclonal ...... 50 µl ...... AB-T134 CD14 Mouse Monoclonal ...... 500 µg ...... AB-412 CD14 Mouse Monoclonal, Biotin-labeled ...... 500 µg ...... AB-410 CD14 Mouse Monoclonal, FITC-labeled ...... 500 µg ...... AB-411 CD1A (T6, LEU6) Mouse Monoclonal ...... 500 µg, 1 mg ...... AB-413 CD2 (T11, LFA-2) Mouse Monoclonal ...... 500 µg, 1 mg ...... AB-414 CD2 Mouse Monoclonal, FITC-labeled ...... 500 µg ...... AB-554 CD20 Recombinant Monoclonal ...... 50 µg, 500 µg, 1 mg . .AB-415 CD21 Mouse Monoclonal ...... 500 µg ...... AB-555 CD21 Mouse Monoclonal, Biotin-labeled ...... 500 µg ...... AB-556

Choline Acetyltransferase (ChAT) , Cat. #AB-N34 A fixed section of rat spinal cord (A) and forebrain (B) was stained with our anti-ChAT (1:2000-4000 dilution). Courtesy of Dr. Ronald G. Wiley. and Robert Kline at Vanderbilt University, Nashville, TN.

A B CD21 Mouse Monoclonal, FITC-labeled ...... 500 µg ...... AB-557 CD22 Mouse Monoclonal ...... 100 µg ...... AB-36 CD25 Mouse Monoclonal ...... 100 µg ...... AB-18 CD25 Rat Monoclonal ...... 100 µg ...... AB-19 CD28 Hamster Monoclonal ...... 500 µg ...... AB-569 CD28 Hamster Monoclonal, Biotin-labeled ...... 500 µg ...... AB-570 CD28 Hamster Monoclonal, FITC-labeled ...... 500 µg ...... AB-571 CD3 Mouse Monoclonal ...... 500 µg, 1 mg ...... AB-416 CD3 Mouse Monoclonal, Biotin-labeled ...... 500 µg ...... AB-418 Page 35 Antibodies (continued) CD3 Mouse Monoclonal, FITC-labeled ...... 500 µg ...... AB-419 CD3 Rat Monoclonal ...... 500 µg ...... AB-417 CD4 Mouse Monoclonal ...... 500 µg ...... AB-420 CD4 Mouse Monoclonal, Biotin-labeled ...... 500 µg ...... AB-422 CD4 Mouse Monoclonal, FITC-labeled ...... 500 µg ...... AB-423 CD4 Rat Monoclonal ...... 500 µg, 1 mg ...... AB-421 CD4 Rat Monoclonal, Biotin-labeled ...... 500 µg, 1 mg ...... AB-583 CD4 Rat Monoclonal, FITC-labeled ...... 500 µg, 1 mg ...... AB-584 CD40 Mouse Monoclonal ...... 500 µg ...... AB-561 CD40 Mouse Monoclonal, Biotin-labeled ...... 500 µg ...... AB-562 CD40 Mouse Monoclonal, FITC-labeled ...... 500 µg ...... AB-563 CD44 Mouse Monoclonal ...... 500 µg ...... AB-426 CD44 Mouse Monoclonal, Biotin-labeled ...... 500 µg ...... AB-424 CD44 Mouse Monoclonal, FITC-labeled ...... 500 µg ...... AB-425 CD44 Rat Monoclonal ...... 500 µg ...... AB-585 CD44 Rat Monoclonal, Biotin-labeled ...... 500 µg ...... AB-586 CD44 Rat Monoclonal, FITC-labeled ...... 500 µg ...... AB-587 CD45 Mouse Monoclonal ...... 500 µg ...... AB-558 CD45 Mouse Monoclonal, Biotin-labeled ...... 500 µg ...... AB-559 CD45 Mouse Monoclonal, FITC-labeled ...... 500 µg ...... AB-560 Mac-1 (CD11b) Mouse Monoclonal, AB-N06 Mac-1, diluted 1000x in pBS + 0.5% Triton X-100 + 5% normal goat serum, incubated for 48 hours at 4ºC. A and B: Mac-1 antibody immunostaining on sections through the lumbosacral spinal cord. A) a deep portion of the ventral horn, B) superficial layers of the dorsal horn. C and D: In vivo penetration of Mac-1 antibody into rat spinal cord. C) white matter of ventral horn, D) dorsal horn. Mac-1 (CD11b) Rat Monoclonal The staining shows binding to cells with microglia-type morphology. The penetration visible Cat. #AB-N05 with immunohistochemical detection was ~350 mm deep. Provided by L.R. Watkins. CD5 Mouse Monoclonal ...... 500 µg ...... AB-427 CD58 Mouse Monoclonal ...... 500 µg ...... AB-572 CD58 Mouse Monoclonal, Biotin-labeled ...... 500 µg ...... AB-573 CD58 Mouse Monoclonal, FITC-labeled ...... 500 µg ...... AB-574 CD8 Mouse Monoclonal ...... 500 µg ...... AB-428 CD8 Mouse Monoclonal, Biotin-labeled ...... 500 µg ...... AB-429 CD8 Mouse Monoclonal, FITC-labeled ...... 500 µg ...... AB-430 CD8 Rat Monoclonal ...... 500 µg ...... AB-575 CD8 Rat Monoclonal, Biotin-labeled ...... 500 µg ...... AB-576 CD8 Rat Monoclonal, FITC-labeled ...... 500 µg ...... AB-577 CD80 Rat Monoclonal ...... 500 µg ...... AB-431 CD86 Rat Monoclonal ...... 500 µg ...... AB-578 CD86 Rat Monoclonal, Biotin-labeled ...... 500 µg ...... AB-579 CD86 Rat Monoclonal, FITC-labeled ...... 500 µg ...... AB-580 CD90 Thy-1 Rat Monoclonal ...... 500 µg ...... AB-432 CD90 Thy-1.1 Rat Monoclonal ...... 500 µg ...... AB-433 CD90 Thy-1.2 Rat Monoclonal ...... 500 µg ...... AB-434 CFP Mouse Monoclonal ...... 100 µg ...... AB-278 Chlamydia LPS Mouse Monoclonal ...... 500 µg ...... AB-435 Chloramphenicol Antibody ...... 100 µg ...... AB-290 Chloramphenicol Antibody, HRP-labeled ...... 100 µg ...... AB-291 Choline Acetyltransferase Rabbit Polyclonal ...... 100 µl ...... AB-N34 Page 36 Antibodies (continued) Choline Acetyltransferase Rabbit Polyclonal, affinity-purified ...... 50 µg ...... AB-N34AP Citrobacter koseri Rabbit Polyclonal ...... 50 µl ...... AB-T056 Citrulline Rabbit Polyclonal ...... 50 µl ...... AB-T127 Competitive inhibitor of the Anti-acetylated Lysine Antibody ...... 5 mg ...... AB-295 Competitive Inhibitor of the Methyl Lysine Antibody ...... 5 mg ...... AB-286 Competitive Inhibitor of the Tri-methyl Lysine Antibody ...... 5 mg ...... AB-287 Corticotropin Releasing Hormone Rabbit Polyclonal ...... 100 µl ...... AB-02 CTLA-4 Hamster Monoclonal ...... 500 µg ...... AB-436 CYP450 (1A2) Mouse Monoclonal ...... 1 ml ...... AB-25 CYP450 (26A1) Mouse Monoclonal ...... 1 ml ...... AB-27 CYP450 (2A6, 2A7, 2A13, and 2B6) Mouse Monoclonal ...... 1 ml ...... AB-22 CYP450 (3A5) Mouse Monoclonal ...... 1 ml ...... AB-23 CYP450 (3A7) Mouse Monoclonal ...... 1 ml ...... AB-24 CYP450 (4F11) Mouse Monoclonal ...... 1 ml ...... AB-26 D-Alanine Rabbit Polyclonal ...... 50 µl ...... AB-T049 D-Aspartic Acid Rabbit Polyclonal ...... 50 µl ...... AB-T046 D-Aspartic Acid Rat Polyclonal ...... 50 µl ...... AB-T047 D-Biotin Rabbit Polyclonal ...... 50 µl ...... AB-T146 D-Cysteine Rabbit Polyclonal ...... 50 µl ...... AB-T050 D-Glutamic Acid Rabbit Polyclonal ...... 50 µl ...... AB-T045 D-Methionine Rabbit Polyclonal ...... 50 µl ...... AB-T051 D-Pantothenic acid Rabbit Polyclonal ...... 50 µl ...... AB-T143 D-Serine Rabbit Polyclonal ...... 50 µl ...... AB-T048 D-Tryptophan Rabbit Polyclonal ...... 50 µl ...... AB-T052 D-Tyrosine Rabbit Polyclonal ...... 50 µl ...... AB-T053 DAT-ECD Rat Monoclonal ...... 100 µg ...... AB-N17 DAT-NT Rat Monoclonal ...... 100 µg ...... AB-N18 Dengue-2 Virus Envelope Mouse Monoclonal ...... 500 µg ...... AB-437 Diamino-Pentane Rabbit Polyclonal ...... 50 µl ...... AB-T135 Dimethylated Arginine Rabbit Polyclonal ...... 100 µg ...... AB-284 Dimethylbenzanthracene (DMBA) Rat Polyclonal ...... 50 µl ...... AB-T136 DL-5-hydroxytryptophan Mouse Monoclonal ...... 50 µl ...... AB-T077 Donkey Anti-Goat IgG, FITC-labeled ...... 500 µg ...... FL-11 Dopamine anti-idiotype Rabbit Polyclonal ...... 50 µl ...... AB-T019 Dopamine Mouse Monoclonal ...... 50 µl ...... AB-T11 Dopamine Rabbit Polyclonal ...... 50 µl ...... AB-T07 Dopamine Rat Polyclonal ...... 50 µl ...... AB-T068 DYKDDDDK-Tag Mouse Monoclonal ...... 100 µg ...... AB-209 E-Selectin Mouse Monoclonal ...... 500 µg, 1 mg ...... AB-438 EBV EBNA1 Mouse Monoclonal ...... 25 µg, 50 µg, 100 µg . .AB-439 Endorphin Beta Rabbit Polyclonal ...... 100 µl ...... AB-10 Enkephalin (Leu5) Rabbit Polyclonal ...... 100 µl ...... AB-03 Enterobacter Cloacae Rabbit Polyclonal ...... 50 µl ...... AB-T157 Eotaxin-1 (CCL11) Mouse Monoclonal ...... 500 µg ...... AB-440 Eotaxin-2 Mouse Monoclonal ...... 500 µg ...... AB-441 Epidermal Growth Factor Mouse Monoclonal ...... 500 µg ...... AB-442 ERK1/ERK2 Rabbit Polyclonal, HRP-labeled ...... 100 µg ...... AB-210

NK-1 Receptor (NK-1r) Affinity purified Rabbit polyclonal Cat. #AB-N33 Ap Staining of NK1r-bearing neurons in dog spinal cord. paraformaldehyde perfused sections of dog spinal cord (cervical dorsal horn) were stained with rabbit anti-dog NK1r antibody by A) enzyme-based immunohistochemistry and B) fluorescent immunohistochemistry. Photos supplied by the laboratory of T. Yaksh. Page 37 Antibodies (continued) Erythropoietin clone NYRhEPO Mouse Monoclonal ...... 500 µg ...... AB-443 Erythropoietin Mouse Monoclonal ...... 50 µg, 500 µg ...... AB-444 Escherichia coli O26:B6 Rabbit Polyclonal ...... 50 µl ...... AB-T165 Escherichia coli O26:B6:H11 Rabbit Polyclonal ...... 50 µl ...... AB-T164 Factor-IX Mouse Monoclonal ...... 500 µg ...... AB-445 FAS (CD95) Blocking Mouse Monoclonal ...... 500 µg, 1 mg ...... AB-446 FAS (CD95) Blocking/Activating Mouse Monoclonal ...... 500 µg, 1 mg ...... AB-447 Fibroblast Growth Factor Basic Mouse Monoclonal ...... 500 µg ...... AB-448 Fibroblast Growth Factor Rabbit Polyclonal, mammalian ...... 100 µl ...... AB-07 Fibroblast Growth Factor Rabbit Polyclonal, rat ...... 100 µl ...... AB-08 FLAG peptide IgG1/kappa Mouse Monoclonal ...... 500 µg ...... AB-450 FLAG peptide IgG2b Mouse Monoclonal ...... 100 µg, 200 µg, 500 µg AB-451 FLAG peptide IgG2b Mouse Monoclonal, HRP-labeled ...... 100 µl ...... AB-449

Somatostatin Receptor -1 (SSTr1) Mouse Monoclonal, Cat. #AB-N35 Immunostaining of CHO cells expressing rat SSTr1 using anti-SSTr1 monoclonal antibody. CHO-K1 cells were transfected with rat SSTr1, fixed with paraformaldehyde and immunostained with anti-SSTr1 monoclonal antibody (5 mg/ml; green) followed by propidium iodide nuclear staining (red).

Folic acid Rat Polyclonal ...... 50 µl ...... AB-T147 Formiate Rat Polyclonal ...... 50 µl ...... AB-T100 G CSF Mouse Monoclonal ...... 500 µg ...... AB-456 G CSF Mouse Monoclonal, Biotin-labeled ...... 500 µg ...... AB-454 G CSF Mouse Monoclonal, FITC-labeled ...... 500 µg ...... AB-455 GABA Rabbit Polyclonal ...... 50 µl ...... AB-T10 GABA Rat Polyclonal ...... 50 µl ...... AB-T158 GAD65 (B78) Human Monoclonal ...... 50 µg ...... AB-N12 GAD65 (B96) Human Monoclonal ...... 50 µg ...... AB-N13 GAPDH Mouse Monoclonal ...... 100 µg ...... AB-267 GAT-1 Rabbit Polyclonal ...... 50 µg ...... AB-N37 GFP Mouse Monoclonal ...... 100 µg ...... AB-268 Gibberellic acid Rat Polyclonal ...... 50 µl ...... AB-T130 Glutathione Rabbit Polyclonal ...... 50 µl ...... AB-T01 Glutathione Rat Polyclonal ...... 50 µl ...... AB-T139 Glycine Rabbit Polyclonal ...... 50 µl ...... AB-T023 GM CSF Mouse Monoclonal ...... 500 µg, 1 mg ...... AB-452 Goat anti-Mouse IgG, Biotin-labeled ...... 1 mg ...... AB-317 Goat Anti-Mouse IgG, FITC-labeled ...... 500 µg ...... FL-07 Goat Anti-Mouse IgG, HRP-labeled ...... 1 mg ...... AB-318 Goat Anti-Rabbit IgG, Biotin-labeled ...... 1 mg ...... AB-319 Goat Anti-Rabbit IgG, FITC-labeled ...... 500 µg ...... FL-04 Goat Anti-Rabbit IgG, HRP-labeled ...... 1 mg ...... AB-320 Goat Anti-Rat IgG, Biotin-labeled ...... 1 mg ...... AB-321 Goat Anti-Rat IgG, FITC-labeled ...... 500 µg ...... FL-10 Goat anti-Rat IgG, HRP-labeled ...... 1 mg ...... AB-322 Gonorrhea Mouse Monoclonal ...... 500 µg ...... AB-453 Growth Hormone IgG1 Mouse Monoclonal ...... 500 µg, 1 mg ...... AB-458 Growth Hormone IgG2b Mouse Monoclonal ...... 25 µg, 50 µg, 100 µg . .AB-457 Growth Hormone Releasing Factor Rabbit Polyclonal, human ...... 100 µl ...... AB-01 Growth Hormone Releasing Factor Rabbit Polyclonal, rat ...... 100 µl ...... AB-16 Growth Hormone Releasing Factor Rabbit Polyclonal, affinity-purified rat ...... 50 µg ...... AB-16AP Page 38 Antibodies (continued) GST (clone PPGSTSHG) Rabbit Polyclonal ...... 100 µl ...... AB-459 GST IgG1 Mouse Monoclonal ...... 500 µg ...... AB-462 GST IgG2b Mouse Monoclonal ...... 100 µg ...... AB-463 GST Mouse Monoclonal, HRP-labeled ...... 100 µl, 200 µl, 500 µl .AB-461 GST Rabbit Polyclonal ...... 250 µg ...... AB-464 GST Rabbit Polyclonal, affinity-purified ...... 100 µg ...... AB-460 GST-Tag Mouse Monoclonal ...... 100 µg ...... AB-211 GST-Tag Rabbit Polyclonal ...... 200 µg ...... AB-276 H-2K Mouse Monoclonal ...... 500 µg ...... AB-465 HA Mouse Monoclonal ...... 100 µg, 200 µg, 500 µg AB-467 HA Mouse Monoclonal, HRP-labeled ...... 100 µl, 200 µl, 500 µl .AB-466 HA Rabbit Polyclonal ...... 100 µl, 200 µl, 500 µl .AB-469 HA-tag Peptide IgG2b/kappa Mouse Monoclonal ...... 500 µg, 1 mg ...... AB-468 Hafnia Alvei Rabbit Polyclonal ...... 50 µl ...... AB-T156 HBsAg Recombinant ...... 10 µg ...... AB-470 HBsAgA Goat Polyclonal ...... 1 ml, 5 ml, 10 ml . . . .AB-471 HBV Mouse Monoclonal ...... 500 µg ...... AB-472 HCV NS3 Mouse Monoclonal ...... 100 µg ...... AB-473 HDV Mouse Monoclonal ...... 100 µg ...... AB-474 HEL Mouse Monoclonal ...... 500 µg ...... AB-475 Heparanase 1 HP130 Mouse Monoclonal ...... 850 µg ...... AB-476 Heparanase-1 3/17 Mouse Monoclonal ...... 100 µg ...... AB-477 Heparanase-1 Rabbit Polyclonal ...... 240 µg ...... AB-478 Hepatitis C Virus Core Mouse Monoclonal ...... 500 µg ...... AB-581 Nerve Growth Factor Receptor His-tag Rabbit Polyclonal ...... 200 µg ...... AB-275 Mouse Monoclonal, AB-N07 His-tag Rabbit Polyclonal, HRP-labeled ...... 1 mg ...... AB-302 Histamine Mouse Monoclonal ...... 50 µl ...... AB-T16 Histamine Rabbit Polyclonal ...... 50 µl ...... AB-T024 Histamine Rat Polyclonal ...... 50 µl ...... AB-T025 Histidine Rabbit Polyclonal ...... 50 µl ...... AB-T038 Histone Deacetylase 10 Rabbit Polyclonal ...... 100 µg ...... AB-314 Histone Deacetylase 11 Rabbit Polyclonal ...... 100 µg ...... AB-315 Histone Deacetylase 2 Rabbit Polyclonal ...... 100 µg ...... AB-307 Histone Deacetylase 4 Rabbit Polyclonal ...... 100 µg ...... AB-308 Histone Deacetylase 5 Rabbit Polyclonal ...... 100 µg ...... AB-309 Nerve Growth Factor Receptor Histone Deacetylase 6 Rabbit Polyclonal ...... 100 µg ...... AB-310 Rabbit polyclonal, AB-N01 Histone Deacetylase 7 Rabbit Polyclonal ...... 100 µg ...... AB-311 Histone Deacetylase 8 Rabbit Polyclonal ...... 100 µg ...... AB-312 Histone Deacetylase 9 Rabbit Polyclonal ...... 100 µg ...... AB-313 Histone H3 Rabbit Polyclonal ...... 100 µg ...... AB-215 Histone H3 Rabbit Polyclonal, HRP-labeled ...... 100 µg ...... AB-214 Histone H4 Rabbit Polyclonal ...... 100 µg ...... AB-216 HIV-1 gp120 Mouse Monoclonal ...... 500 µg ...... AB-479 HIV-1 gp120 Purified Rabbit Polyclonal ...... 10 µg ...... AB-480 HIV-1 gp120 Rabbit Polyclonal ...... 100 µl ...... AB-481 HIV-1 gp41 Mouse Monoclonal ...... 500 µg ...... AB-482 HIV-1 gp41 Rabbit Polyclonal ...... 1 ml ...... AB-483 HIV-1 p24 Mouse Monoclonal ...... 500 µg ...... AB-484 HIV-2 gp39 Mouse Monoclonal ...... 500 µg ...... AB-485 HIV-2 gp39 Rabbit Polyclonal ...... 1 ml ...... AB-486 Homocysteic acid Rabbit Polyclonal ...... 50 µl ...... AB-T096 Homocysteine Rabbit Polyclonal ...... 50 µl ...... AB-T035 Homovanillic acid Rat Polyclonal ...... 50 µl ...... AB-T098 HRP Rabbit Polyclonal ...... 1 mg ...... AB-279 HTLV-1 TAX Mouse Monoclonal ...... 500 µg ...... AB-582 Human IgG Rabbit Polyclonal ...... 1 g ...... AB-297 Page 39 Antibodies (continued) Human IgG Rabbit Polyclonal, HRP-labeled ...... 1 mg ...... AB-298 Human Serum Albumin Rabbit Polyclonal, affinity-purified ...... 1 mg ...... AB-40AP Human Serum Albumin Rabbit Polyclonal, HRP-labeled ...... 1 mg ...... AB-217 Ibuprofen Rabbit Polyclonal ...... 50 µl ...... AB-T162 Ig Kappa Light Chain Mouse Monoclonal ...... 500 µg ...... AB-488 Ig Lambda Light Chain Mouse Monoclonal ...... 500 µg ...... AB-489 IgA 1&2 Mouse Monoclonal ...... 500 µg ...... AB-490 IgA Sec Component Mouse Monoclonal ...... 500 µg ...... AB-491 IgG-Fc Mouse Monoclonal ...... 500 µg ...... AB-492 Indole 3 Acetic Acid Rabbit Polyclonal ...... 50 µl ...... AB-T129 Influenza A Virus H1N1 (Hemagglutinin) Mouse Monoclonal ...... 10 µg, 50 µg, 1 mg . . .AB-493 Influenza A Virus H1N1 (Hemagglutinin) Rabbit Polyclonal ...... 5 µg, 15 µg, 100 µg . . .AB-494 Influenza A Virus H3N2 (Hemagglutinin) Mouse Monoclonal 10 µg, 50 µg, 1 mg . . .AB-495 Influenza A Virus H3N2 (Hemagglutinin) Rabbit Polyclonal . 5 µg, 15 µg, 100 µg . . .AB-496 Influenza A Virus H5N1 (Hemagglutinin) Mouse Monoclonal 10 µg, 50 µg, 1 mg . . .AB-497 Influenza B Jiangsu Rabbit Polyclonal ...... 100 µg ...... AB-498 Influenza B Virus Mouse Monoclonal ...... 10 µg ...... AB-499 Insulin Mouse Monoclonal ...... 200 µg ...... AB-500 Interferon-alpha Neutralizing Mouse Monoclonal ...... 500 µg, 1 mg ...... AB-501 Interferon-alpha Western Blot Mouse Monoclonal ...... 500 µg ...... AB-502 Interferon-beta Mouse Monoclonal ...... 500 µg, 1 mg ...... AB-503 Interferon-gamma Mouse Monoclonal ...... 500 µg, 1 mg ...... AB-504 Interferon-gamma Rat Monoclonal ...... 500 µg ...... AB-487 Interleukin-1 beta Mouse Monoclonal ...... 500 µg ...... AB-507 Serotonin Transporter (SERT) Interleukin-1 beta Mouse Monoclonal, Biotin-labeled ...... 500 µg ...... AB-505 Cat. #AB-N09 Interleukin-1 beta Mouse Monoclonal, FITC-labeled ...... 500 µg ...... AB-506 Interleukin-1 Receptor Antagonist Mouse Monoclonal . . . . . 500 µg ...... AB-508 Interleukin-10 Mouse Monoclonal ...... 500 µg ...... AB-509 Interleukin-10 Rat Monoclonal ...... 500 µg ...... AB-510 Interleukin-12 p40 Rat Monoclonal ...... 500 µg ...... AB-511 Interleukin-12 p75 Rat Monoclonal ...... 500 µg ...... AB-512 Interleukin-15 Mouse Monoclonal ...... 500 µg ...... AB-513 Interleukin-2 Mouse Monoclonal ...... 500 µg ...... AB-514 Interleukin-2 Rat Monoclonal ...... 500 µg ...... AB-515 Interleukin-2 receptor Mouse Monoclonal ...... 500 µg ...... AB-516 Interleukin-2 Receptor Rat Monoclonal ...... 500 µg ...... AB-517 Interleukin-3 Mouse Monoclonal ...... 500 µg ...... AB-518 Interleukin-4 Mouse Monoclonal ...... 500 µg ...... AB-519 Interleukin-4 Rat Monoclonal ...... 500 µg ...... AB-520 Interleukin-6 Mouse Monoclonal ...... 500 µg ...... AB-521 Interleukin-7 Mouse Monoclonal ...... 500 µg ...... AB-522 Interleukin-8 Mouse Monoclonal ...... 500 µg ...... AB-523 JNK Rabbit Polyclonal ...... 100 µg ...... AB-220 JNK Rabbit Polyclonal, HRP-labeled ...... 100 µg ...... AB-219 Kainic Acid Rabbit Polyclonal ...... 50 µl ...... AB-T159 Klebsiella Pneumoniae Rabbit Polyclonal ...... 50 µl ...... AB-T169 Kynurenic acid Rabbit Polyclonal ...... 50 µl ...... AB-T094 L-Arginine Rabbit Polyclonal ...... 50 µl ...... AB-T126 L-Aspartic Acid (L-Aspartate) Rabbit Polyclonal ...... 50 µl ...... AB-T022 L-Cysteine Rabbit Polyclonal ...... 50 µl ...... AB-T034 L-DOPA anti-idiotype Rabbit Polyclonal ...... 50 µl ...... AB-T020 L-DOPA Mouse Monoclonal ...... 50 µl ...... AB-T17 L-DOPA Rabbit Polyclonal ...... 50 µl ...... AB-T067 L-Glutamate anti-idiotype Rabbit Polyclonal ...... 50 µl ...... AB-T021 L-Glutamate Mouse Monoclonal ...... 50 µl ...... AB-T12 L-Glutamate Rabbit Polyclonal ...... 50 µl ...... AB-T08 Page 40 Antibodies (continued) L-Glutamine Rat Polyclonal ...... 50 µl ...... AB-T13 L-Isoleucine Rabbit Polyclonal ...... 50 µl ...... AB-T041 L-Kynurenine Rabbit Polyclonal ...... 50 µl ...... AB-T152 L-Leucine Rabbit Polyclonal ...... 50 µl ...... AB-T040 L-Norephedrine Rabbit Polyclonal ...... 50 µl ...... AB-T167 L-Serine Rabbit Polyclonal ...... 50 µl ...... AB-T039 L-Threonine Rabbit Polyclonal ...... 50 µl ...... AB-T043 L-Valine Rabbit Polyclonal ...... 50 µl ...... AB-T042 L.Kynurenine Mouse Monoclonal ...... 50 µl ...... AB-T171 Leptin Mouse Monoclonal ...... 500 µg ...... AB-524 LPL Mouse Monoclonal ...... 100 µg ...... AB-221 Luteinizing Hormone Releasing Hormone Rabbit Polyclonal ...... 100 µl ...... AB-06 Mac-1 (CD11b) Mouse Monoclonal ...... 100 µg ...... AB-N06 Mac-1 (CD11b) Rat Monoclonal ...... 100 µg ...... AB-N05 Macrophage Inflammatory Protein-3 alpha (CCL20) Mouse Monoclonal ...... 500 µg ...... AB-526 Macrophage Inflammatory Protein-3 beta (CCL19) Mouse Monoclonal ...... 500 µg ...... AB-527 Macrophage Inflammatory Protein-3 Mouse Monoclonal ...... 500 µg ...... AB-528 Macrophage/Monocyte Chemotactic & Activating Factor Mouse Monoclonal ...... 500 µg ...... AB-529 Macrophage/Monocyte Chemotactic Protein-3/MARC Mouse Monoclonal ...... 500 µg ...... AB-530 Malondialdehyde Rabbit Polyclonal ...... 50 µl ...... AB-T090 MBP Mouse Monoclonal ...... 100 µg ...... AB-531 MBP Rabbit Polyclonal ...... 100 µg ...... AB-222 Melanopsin Rabbit Polyclonal ...... 25 µ ...... AB-N38 Melanopsin Rabbit Polyclonal, affinity-purified ...... 50 µg ...... AB-N39 Melatonin Rabbit Polyclonal ...... 50 µl ...... AB-T079 Metabotrophic Glutamate Receptor 2 (mGluR2) Mouse Monoclonal ...... 100 µg ...... AB-N32 Methionine Rabbit Polyclonal ...... 50 µl ...... AB-T036 Methionine Rat Polyclonal ...... 50 µl ...... AB-T037 Methylated Arginine Rabbit Polyclonal ...... 100 µg ...... AB-285 Methylated Lysine Rabbit Polyclonal ...... 100 µg ...... AB-225 Methylated Lysine Rabbit Polyclonal, Biotin-labeled ...... 100 µg ...... AB-223 Methylated Lysine Rabbit Polyclonal, FITC-labeled ...... 100 µg ...... AB-271 Methylated Lysine Rabbit Polyclonal, HRP-labeled ...... 100 µg ...... AB-224

A B Somatostatin Receptor-5 (SSTr5) Mouse Monoclonal, Cat. #AB-N24 Immunostaining of CHO cells expressing rat SSTr5 using anti-SSTr5 monoclonal antibody. CHO-K1 cells were transfected with rat SSTr5, fixed with paraformaldehyde and A) immunostained with anti-SSTr5 monoclonal antibody (5 mg/ml; green) followed by propidium iodide nuclear staining (red) and B) same as A except that 5 mg/ml of normal mouse IgM was used as control followed by nuclear staining. MHC Class I (H-2K) Mouse Monoclonal, Biotin-labeled ...... 500 µg ...... AB-564 MHC Class I (H-2K) Mouse Monoclonal, FITC-labeled ...... 500 µg ...... AB-565 MHC Class II (I-A) Mouse Monoclonal ...... 500 µg ...... AB-566 MHC Class II (I-A) Mouse Monoclonal, Biotin-labeled ...... 500 µg ...... AB-567 MHC Class II (I-A) Mouse Monoclonal, FITC-labeled ...... 500 µg ...... AB-568 MIP-1a (CCL3) Mouse Monoclonal ...... 500 µg, 1 mg ...... AB-525 MMP-1 Mouse Monoclonal ...... 1 ml ...... AB-29 MMP-2 Mouse Monoclonal ...... 1 ml ...... AB-30 MMP-3 Mouse Monoclonal ...... 1 ml ...... AB-31 MMP-9 Mouse Monoclonal ...... 1 ml ...... AB-32 MOG Mouse Monoclonal ...... 500 µg ...... AB-532 Morganella morganii Rabbit Polyclonal ...... 50 µl ...... AB-T055 MRSA Mouse Monoclonal ...... 500 µg, 1 mg ...... AB-533 MSH-gamma-1 Rabbit Polyclonal ...... 100 µl ...... AB-11 Myc Mouse Monoclonal ...... 100 µg, 200 µg, 500 µg AB-535 Page 41 Antibodies (continued) Myc Mouse Monoclonal, HRP-labeled ...... 100 µl ...... AB-534 Myc Rabbit Polyclonal ...... 100 µl, 200 µl, 500 µl .AB-536 Myc-tag Mouse Monoclonal ...... 100 µg ...... AB-226 Myelin Basic Protein, Biotin-labeled ...... 1 mg ...... AB-304 Myristic acid Rat Polyclonal ...... 50 µl ...... AB-T086 N-acetyl-cysteine Rat Polyclonal ...... 50 µl ...... AB-T148 Neurotrophin-4 Mouse Monoclonal ...... 500 µg, 1 mg ...... AB-537 Neutrophil Activating Protein-2 (CXCL7) Mouse Monoclonal ...... 500 µg ...... AB-538 NGFr (ME20.4, p75) Mouse Monoclonal ...... 100 µg ...... AB-N07 NGFr (mu p75) Rabbit Polyclonal ...... 100 µl ...... AB-N01 NGFr (mu p75) Rabbit Polyclonal, affinity-purified ...... 50 µg ...... AB-N01AP NGFr (mu p75) Rabbit Polyclonal, Alexa488-labeled affinity-purified ...... 25 µg, 100 µg ...... FL-09 NGFr (mu p75) Rabbit Polyclonal, Cy3-labeled affinity-purified ...... 25 µg, 100 µg ...... FL-05 NGFr (mu p75) Rabbit Polyclonal, Cy5-labeled affinity-purified ...... 25 µg, 100 µg ...... FL-06 Nicotinamide Rat Polyclonal ...... 50 µl ...... AB-T150 Nicotinic Acetylcholine Receptor alpha 1 (mAb 35) Rat Monoclonal ...... 100 µg ...... AB-N36 Nitrendipine Rabbit Polyclonal ...... 50 µl ...... AB-T076 NK-1 Receptor Rabbit Polyclonal, affinity-purified ...... 50 µg ...... AB-N33AP NO-Acetyl Salicylic AcidRat Polyclonal ...... 50 µl ...... AB-T075 NO-Dopamine Rat Polyclonal ...... 50 µl ...... AB-T122 NO-Glutathione Rat Polyclonal ...... 50 µl ...... AB-T124 NO-Histidine Rat Polyclonal ...... 50 µl ...... AB-T117 NO-L-Asparagine Rat Polyclonal ...... 50 µl ...... AB-T120 NO-L-Cystein Mouse Monoclonal ...... 50 µl ...... AB-T125 NO-L-Cystein Rat Polyclonal ...... 50 µl ...... AB-T113 NO-L-DOPA Rat Polyclonal ...... 50 µl ...... AB-T121 NO-L-Glutamine Rat Polyclonal ...... 50 µl ...... AB-T14 NO-Lysine Rabbit Polyclonal ...... 50 µl ...... AB-T118 NO-Methionine Rat Polyclonal ...... 50 µl ...... AB-T119 NO-Tryptophan Rabbit Polyclonal ...... 50 µl ...... AB-T116 NO-Tryptophan Rat Polyclonal ...... 50 µl ...... AB-T115 NO-Tyramine Rat Polyclonal ...... 50 µl ...... AB-T123 NO-Tyrosine Rabbit Polyclonal ...... 50 µl ...... AB-T114 NO2-Serotonin Rabbit Polyclonal ...... 50 µl ...... AB-T110 NO2-Serotonin Rat Polyclonal ...... 50 µl ...... AB-T111 NO2-Tyrosine Rabbit Polyclonal ...... 50 µl ...... AB-T108 NO2-Tyrosine Rat Polyclonal ...... 50 µl ...... AB-T109 NO2-Tyrosine-Diaminopentane Rat Polyclonal ...... 50 µl ...... AB-T112 Noradrenaline Rabbit Polyclonal ...... 50 µl ...... AB-T06 NSE Mouse Monoclonal ...... 1 ml ...... AB-33 Ochratoxin A Rabbit Polyclonal ...... 100 µg ...... AB-227 Ochratoxin A Rabbit Polyclonal, HRP-labeled ...... 100 µg ...... AB-294 Octopamine Rabbit Polyclonal ...... 50 µl ...... AB-T070 Ornithine Rabbit Polyclonal ...... 50 µl ...... AB-T132 OX7 (Anti-Thy 1) Mouse Monoclonal ...... 100 µg ...... AB-N08 p33 ING1 Rabbit Polyclonal ...... 100 µg ...... AB-230 p33 ING1 Rabbit Polyclonal, Biotin-labeled ...... 100 µg ...... AB-228 p33 ING1 Rabbit Polyclonal, HRP-labeled ...... 100 µg ...... AB-229 p38 Hog Rabbit Polyclonal ...... 100 µg ...... AB-288 p42 ERK2 (p42 MAPK) Rabbit Polyclonal ...... 100 µg ...... AB-232 p42 ERK2 Rabbit Polyclonal, HRP-labeled ...... 100 µg ...... AB-231 p44 ERK1 (p44 MAPK) Rabbit Polyclonal ...... 100 µg ...... AB-235 p44 ERK1 Rabbit Polyclonal, Biotin-labeled ...... 100 µg ...... AB-233 p44 ERK1 Rabbit Polyclonal, HRP-labeled ...... 100 µg ...... AB-234 p53 (ser-37) Rabbit Polyclonal ...... 100 µg ...... AB-238 p53 Mouse Monoclonal ...... 100 µg ...... AB-539 Page 42 Antibodies (continued) p53 Rabbit Polyclonal ...... 100 µg ...... AB-237 p53 Rabbit Polyclonal, HRP-labeled ...... 100 µg ...... AB-236 p53 scFv Recombinant Mouse Monoclonal ...... 2 µg, 10 µg ...... AB-301 p70 S6K Rabbit Polyclonal ...... 100 µg ...... AB-241 p70 S6K Rabbit Polyclonal, Biotin-labeled ...... 100 µg ...... AB-239 p70 S6K Rabbit Polyclonal, HRP-labeled ...... 100 µg ...... AB-240 p90 RSK1 Rabbit Polyclonal ...... 100 µg ...... AB-244 p90 RSK1 Rabbit Polyclonal, Biotin-labeled ...... 100 µg ...... AB-242 p90 RSK1 Rabbit Polyclonal, HRP-labeled ...... 100 µg ...... AB-243 Pantoea agglomerans (Erwinia herbicola) Rabbit Polyclonal ...... 50 µl ...... AB-T064 PAP-1 Rabbit Polyclonal ...... 10 µg ...... AB-540 Phenyl acetic acid Rabbit Polyclonal ...... 50 µl ...... AB-T097 Phenyl-acetic acid Rat Polyclonal ...... 50 µl ...... AB-T099 Phenylalanine Rabbit Polyclonal ...... 50 µl ...... AB-T032 Phenylethylamine Rabbit Polyclonal ...... 50 µl ...... AB-T073 Phospho-Crebtide Rabbit Polyclonal ...... 100 µg ...... AB-247 Phospho-Crebtide Rabbit Polyclonal, Biotin-labeled ...... 100 µg ...... AB-245 Phospho-Crebtide Rabbit Polyclonal, HRP-labeled ...... 100 µg ...... AB-246 Phospho-Crosstide Rabbit Polyclonal ...... 100 µg ...... AB-249 Phospho-Crosstide Rabbit Polyclonal, Biotin-labeled ...... 100 µg ...... AB-289 Phospho-Crosstide Rabbit Polyclonal, HRP-labeled ...... 100 µg ...... AB-248 Phospho-Serine Rabbit Polyclonal ...... 100 µg ...... AB-252

n Phospho-Serine Rabbit Polyclonal, Biotin-labeled . . . 100 µg ...... AB-250 i s

n Phospho-Serine Rabbit Polyclonal, HRP-labeled . . . . 100 µg ...... AB-251 o c s i Phospho-Threonine Rabbit Polyclonal ...... 100 µg ...... AB-255 W

v Phospho-Threonine Rabbit Polyclonal, Biotin-labeled 100 µg ...... AB-253 i n U :

Phospho-Threonine Rabbit Polyclonal, HRP-labeled . 100 µg ...... AB-254 y , b d l

e Phospho-Tyrosine Rabbit Polyclonal ...... 100 µg ...... AB-258 d i f e i n l

p Phospho-Tyrosine Rabbit Polyclonal, Biotin-labeled . 100 µg ...... AB-256 w p o r u

s Phospho-Tyrosine Rabbit Polyclonal, HRP-labeled . . 100 µg ...... AB-257 B

o k t r Phytanic Acid Rabbit Polyclonal ...... 50 µl ...... AB-T163 o a h

M Angiotensin II receptor (AT-1Ar) P Picolinic Acid Rabbit Polyclonal ...... 50 µl ...... AB-T154 Cat. #AB-N25 Ap PLP Mouse Monoclonal ...... 500 µg ...... AB-541 PRAPDX-1 Rabbit Polyclonal ...... 10 µl ...... AB-542 n

i Progesterone Rabbit Polyclonal ...... 100 µg ...... AB-292 s n

o Progesterone Rabbit Polyclonal, HRP-labeled ...... 100 µg ...... AB-293 c s i Proteus mirabilis Rabbit Polyclonal ...... 50 µl ...... AB-T054 W

v i Pseudomonas aeruginosa Rabbit Polyclonal ...... 50 µl ...... AB-T057 n U :

y Pseudomonas aeruginosa Rat Polyclonal ...... 50 µl ...... AB-T058 , b d l

e d

i Pseudomonas aureofasciens Rat Polyclonal ...... 50 µl ...... AB-T060 f e i n l p

w Pseudomonas blatchfordae Rat Polyclonal ...... 50 µl ...... AB-T061 p o r u s B Pseudomonas fluorescens Rabbit Polyclonal ...... 50 µl ...... AB-T063

o k t r o a Pseudomonas marginalis Rat Polyclonal ...... 50 µl ...... AB-T059

h Angiotensin II receptor (AT-1Br) M P Cat. #AB-N26 Ap Pseudomonas putida Rabbit Polyclonal ...... 50 µl ...... AB-T138 Pseudomonas stutzeri Rabbit Polyclonal ...... 50 µl ...... AB-T066 Pyridoxal Rabbit Polyclonal ...... 50 µl ...... AB-T149 n

i Pyridoxine Rat Polyclonal ...... 50 µl ...... AB-T144 s n

o Quinaldic Acid Rabbit Polyclonal ...... 50 µl ...... AB-T153 c s i Quinolinic Acid Mouse Monoclonal ...... 50 µl ...... AB-T170 W

v

i Quinolinic acid Rabbit Polyclonal ...... 50 µl ...... AB-T095 n U :

Rabbit Anti-Goat IgG, Biotin-labeled ...... 1 mg ...... AB-323 y , b d l

e

d Rabbit Anti-Goat IgG, FITC-labeled ...... 1 mg ...... AB-324 i f e i n l

p Rabbit Anti-Goat IgG, HRP-labeled ...... 1 mg ...... AB-325 w p o r u s

B Rabbit Anti-Human IgG, Biotin-labeled ...... 1 mg ...... AB-326

o k t r o

a Rabbit Anti-Human IgG, FITC-labeled ...... 1 mg ...... AB-327

h Angiotensin II receptor (AT-2r) M P Cat. #AB-N28 Ap Rabbit Anti-Human IgG, HRP-labeled ...... 1 mg ...... AB-328 Antibodies (continued) Rabbit anti-Human Serum Albumin, HRP-labeled ...... 1 mg ...... AB-303 Rabbit Anti-Mouse IgG, Biotin-labeled ...... 1 mg ...... AB-329 Rabbit Anti-Mouse IgG, FITC-labeled ...... 1 mg ...... AB-330 Rabbit Anti-Mouse IgG, HRP-labeled ...... 1 mg ...... AB-331 Rabbit IgG Goat Polyclonal ...... 1 g ...... AB-299 Rabbit IgG Goat Polyclonal, HRP-labeled ...... 1 mg ...... AB-300 Retinoic acid Rabbit Polyclonal ...... 50 µl ...... AB-T140 Riboflavin Rat Polyclonal ...... 50 µl ...... AB-T142 Rotenone Rat Polyclonal ...... 50 µl ...... AB-T107 Saporin Chicken Polyclonal, affinity-purified ...... 50 µg ...... AB-17AP Saporin Goat Polyclonal ...... 100 µl ...... AB-15 Saporin Goat Polyclonal, affinity-purified ...... 50 µg ...... AB-15AP Saporin Goat Polyclonal, FITC-labeled affinity-purified ...... 25 µg, 100 µg ...... FL-02 Saporin Goat Polyclonal, HRP-labeled ...... 200 µg ...... AB-15HRP Saporin Rabbit Polyclonal, affinity-purified ...... 50 µg ...... AB-41AP Sarcosine Rabbit Polyclonal ...... 50 µl ...... AB-T173 SARS Nucleocapsid Mouse Monoclonal ...... 100 µg ...... AB-543 SARS Nucleocapsid Rabbit Polyclonal ...... 100 µg ...... AB-544 SARS Spike Mouse Monoclonal ...... 100 µg ...... AB-545 SARS Spike Rabbit Polyclonal ...... 100 µg ...... AB-546 Sauvagine Rabbit Polyclonal ...... 100 µl ...... AB-14 SCD-1 Mouse Monoclonal ...... 100 µg ...... AB-259 Serotonin anti-idiotype Mouse Monoclonal ...... 50 µl ...... AB-T018 SERT Mouse Monoclonal ...... 100 µg ...... AB-N09 Somatostatin Receptor-1 (SSTr1) Mouse Monoclonal ...... 50 µg ...... AB-N35 Somatostatin Receptor-1 (SSTr1) Rabbit Polyclonal ...... 100 µl ...... AB-N19 Somatostatin Receptor-1 (SSTr1) Rabbit Polyclonal, affinity-purified ...... 50 µg ...... AB-N20AP Somatostatin Receptor-2 (SSTr2) Rabbit Polyclonal ...... 100 µl ...... AB-N22 Somatostatin Receptor-4 (SSTr4) Rabbit Polyclonal, affinity-purified ...... 50 µg ...... AB-N21AP Somatostatin Receptor-5 (SSTr5) Mouse Monoclonal ...... 50 µg ...... AB-N24 Somatostatin-14 Rabbit Polyclonal ...... 100 µl ...... AB-04 Somatostatin-28 Rabbit Polyclonal ...... 100 µl ...... AB-05 Spermine Rabbit Polyclonal ...... 50 µl ...... AB-T133 Staphylococcus Aureus Rabbit Polyclonal ...... 50 µl ...... AB-T161 Stat1 Rabbit Polyclonal ...... 100 µg ...... AB-260 Stat3 Rabbit Polyclonal ...... 100 µg ...... AB-261 Stat5 Rabbit Polyclonal ...... 100 µg ...... AB-262 Stenotrophomonas maltophilia Rabbit Polyclonal ...... 50 µl ...... AB-T065 Stenotrophomonas maltophilia Rat Polyclonal ...... 50 µl ...... AB-T062 Substance P Rabbit Polyclonal ...... 100 µl ...... AB-N10 Succinate Rat Polyclonal ...... 50 µl ...... AB-T101 Taurine Rabbit Polyclonal ...... 50 µl ...... AB-T026 Taurine Rat Polyclonal ...... 50 µl ...... AB-T028 Taurine-GA-Diaminopentane Rabbit Polyclonal ...... 50 µl ...... AB-T027 Tetanus Recombinant Monoclonal ...... 10 µg ...... AB-547 Tetrodotoxin Rabbit Polyclonal ...... 50 µl ...... AB-T15 Thiamine Rat Polyclonal ...... 50 µl ...... AB-T141 Thioctic acid Rat Polyclonal ...... 50 µl ...... AB-T088 TIMP-1 Mouse Monoclonal ...... 1 ml ...... AB-34 TIMP-2 Mouse Monoclonal ...... 1 ml ...... AB-35 Trans-hydroxyproline Rabbit Polyclonal ...... 50 µl ...... AB-T044 Transforming Growth Factor-beta Mouse Monoclonal ...... 500 µg ...... AB-548 TRF1 Mouse Monoclonal ...... 1 ml ...... AB-37 Tri-methyl Lysine Rabbit Polyclonal ...... 100 µg ...... AB-265 Tri-methyl Lysine Rabbit Polyclonal, Biotin-labeled ...... 100 µg ...... AB-263 Tri-methyl Lysine Rabbit Polyclonal, FITC-labeled ...... 100 µg ...... AB-272 Page 44 Antibodies (continued) Tri-methyl Lysine Rabbit Polyclonal, HRP-labeled ...... 100 µg ...... AB-264 trkA Rabbit Polyclonal ...... 100 µg ...... AB-N03 Tryptamine Rabbit Polyclonal ...... 50 µl ...... AB-T04 Tryptophan Rabbit Polyclonal ...... 50 µl ...... AB-T05 TSH Receptor (A10) Mouse Monoclonal ...... 100 µg ...... AB-N16 TSH Receptor (A7) Mouse Monoclonal ...... 100 µg ...... AB-N14 TSH Receptor (A9) Mouse Monoclonal ...... 100 µg ...... AB-N15 Tumor Necrosis Factor-alpha Mouse Monoclonal ...... 500 µg ...... AB-549 Tyramine Rabbit Polyclonal ...... 50 µl ...... AB-T071 Tyramine Rat Polyclonal ...... 50 µl ...... AB-T072 Tyrosine Rabbit Polyclonal ...... 50 µl ...... AB-T030 Tyrosine Rat Polyclonal ...... 50 µl ...... AB-T031 Uric Acid Rabbit Polyclonal ...... 50 µl ...... AB-T168 V5-Tag Mouse Monoclonal ...... 100 µg ...... AB-266 Valeric acid Rabbit Polyclonal ...... 50 µl ...... AB-T089 Valproic Acid Rabbit Polyclonal ...... 50 µl ...... AB-T160 Vascular Endothelial Growth Factor Mouse Monoclonal ...... 500 µg ...... AB-550 Vimentin Mouse Monoclonal ...... 500 µg, 1 mg ...... AB-553 Vimentin Mouse Monoclonal, Biotin-labeled ...... 500 µg, 1 mg ...... AB-551 Vimentin Mouse Monoclonal, FITC-labeled ...... 500 µg, 1 mg ...... AB-552 YFP Mouse Monoclonal ...... 100 µg ...... AB-277

Do you have an idea for a new target? Contact us with your suggestion. If your target is chosen for development of a targeted toxin, we will provide the conjugate to you at no charge. Just send an email to Denise Higgins, Vice President of Business Development at: [email protected].

Page 45 Proteins, Peptides & Antigens

This is an alphabetical listing of our proteins, peptides, and antigens. More information including data sheets can be found on our website at www.ATSbio.com.

1,3-Butadiene, Conjugated (Cat. #AG-114) Alpha-1 Proteinase Inhibitor 3-Indolacetic Acid, Conjugated (Cat. #AG-107) Alpha-2 Macroglobulin Protein 4-1BB Ligand Human Recombinant Alpha-Internexin Human Recombinant 4-1BB Receptor Human Recombinant Alpha-Synuclein Human Recombinant 4,5-Dihydroxytryptamine, Conjugated (Cat. #AG-011) Alpha-Tocopherol, Conjugated (Cat. #AG-066) 5-Hydroxytryptamine, Conjugated (Cat. #AG-012) Amino-levulinic Acid, Conjugated (Cat. #AG-101) 5-Hydroxytryptophan, Conjugated (Cat. #AG-014) AminoAcylase-1 Human Recombinant 5-Hydroxytryptophol, Conjugated (Cat. #AG-015) Aminopeptidase Aeromonas Recombinant 5-Methoxytryptamine, Conjugated (Cat. #AG-017) Amyloid P Component Human Recombinant 5-Methoxytryptophan, Conjugated (Cat. #AG-016) Angiopoietin-1 Human Recombinant 5,6-Dihydroxytryptamine, Conjugated (Cat. #AG-035) Angiopoietin-2 Human Recombinant 5,7-Dihydroxytryptamine, Conjugated (Cat. #AG-037) Angiopoietin-like Protein 3 Human Recombinant 6-Hydroxydopamine, Conjugated (Cat. #AG-003) Angiopoietin-like Protein 4 Human Recombinant 6-Hydroxytryptamine, Conjugated (Cat. #AG-013) Angiostatin Kringles 1-3 Human Recombinant Abscissic Acid, Conjugated (Cat. #AG-109) Angiostatin Kringles 1-4 Acetyl Salicylic Acid, Conjugated (Cat. #AG-068) Angiotensin Acetyl-Coenzyme A acetyltransferase 2 Human Recombinant Angiotensin II receptor (AT-1Ar) Peptide (Cat. #PR-25) Acetylcholine, Conjugated (Cat. #AG-030) Angiotensin II receptor (AT-1Br) Peptide (Cat. #PR-26) Acid Phosphatase-1 Human Recombinant Angiotensin II receptor (AT-2r) Peptide (Cat. #PR-28) Acrolein, Conjugated (Cat. #AG-059) Annexin 1 Human Recombinant Actin Annexin 7 Human Recombinant Actin Gamma 1 Human Recombinant Annexin 9 Human Recombinant Actin-Like 6A Human Recombinant Anterior Gradient Protein 2 Homolog Human Recombinant Activated Protein C Human Recombinant Anthranilic Acid, Conjugated (Cat. #AG-121) Activating Transcription Factor-2 Human Recombinant Antide Hormone Activin-A Human Recombinant Apo Transferrin Acyl-Coenzyme A Dehydrogenase 8 Human Recombinant APO-D GST Tag Human Recombinant ADAM 12 S Isoform Human Recombinant Apoliprotein-D Human Recombinant Adenosine 5" Triphosphate Sulfurylase Yeast Recombinant Apoliprotein-J Adenosine Deaminase tRNA-Specific 1 Human Recombinant Apoliprotein-J Canine Recombinant Adenylate Kinase 2 Human Recombinant Apoliprotein-J Canine Recombinant, HEK Adenylate Kinase 3 Human Recombinant Apoliprotein-J Human Recombinant Adiponectin Globular Human Recombinant Apoliprotein-J Mouse Recombinant Adiponectin Globular Human Recombinant, His tag Apoliprotein-J Rat Recombinant Adiponectin Globular Mouse Recombinant Aprotinin Adiponectin Human Recombinant Aprotinin Bovine Recombinant Adiponectin Human Recombinant, HEK Argipressin Hormone Adiponectin Human Recombinant, His tag Artemin Human Recombinant Adiponectin Human Recombinant, Trimeric Ascorbic Acid, Conjugated (Cat. #AG-113) Adiponectin Mouse Recombinant, HEK ASF1 Anti-Silencing Function 1 Homolog A Human Recombinant Adiponectin Mouse Recombinant, His tag Assembly Protein Complex 2 Human Recombinant Adiponectin Mouse Recombinant, Trimeric Assembly Protein Complex 3 Human Recombinant Adipose Differentiation-Related Protein Human Recombinant Atosiban Hormone Adrenaline, Conjugated (Cat. #AG-005) Autophagy Related 5 Human Recombinant Adrenocorticotropic Hormone Avidin Agmatine, Conjugated (Cat. #AG-111) Avidin HRP-labeled (Cat. #PR-10) Agouti–Related Protein Human Recombinant Azelaic Acid, Conjugated (Cat. #AG-067) AITRL Human Recombinant B-Cell Leukemia/Lymphoma 2 -BH1 Human Recombinant AKT1 Human Recombinant B-Cell Leukemia/Lymphoma 2 -BH2 Human Recombinant Alanine Aminotransferase Human Recombinant B-Cell Leukemia/Lymphoma 2 -BH3 Human Recombinant Aldehyde Dehydrogenase 2 Human Recombinant B-Cell Leukemia/Lymphoma 2 -BH4 Human Recombinant Aldo-Keto Reductase Family 1 Member B10 Human Recombinant B-Cell Leukemia/Lymphoma 2 -NWGR Human Recombinant Aldo-Keto Reductase Family 1 Member C3 Human Recombinant B-Cell Leukemia/Lymphoma 2 Human Recombinant Aldose Reductase Human Recombinant B-Cell Leukemia/Lymphoma 2 Human Recombinant, His tag ALK-P80 Human Recombinant B-Cell Leukemia/Lymphoma 2 XL Human Recombinant Alkaline Phosphatase B-Cell Leukemia/Lymphoma 2 XL Human Recombinant, GST Tag Alpha Actinin B-Cell Leukemia/Lymphoma 6 Human Recombinant Alpha Fetaprotein B-Cell Lymphoma Protein 2 Alpha Human Recombinant, His tag Alpha-1 AntiChymotrypsin B-Cell Maturation Antigen Human Recombinant Alpha-1 Antitrypsin Human Recombinant B-type Natriuretic Protein Alpha-1 Microglobulin Protein B-type Natriuretic Protein Human Recombinant Page 46 Proteins, Peptides & Antigens (continued) B-type Natriuretic Protein Human Recombinant, His tag C3c Human Complement Component (Cat. #PRP-555) b2 Glycoprotein-I C4c Human Complement Component b2 Glycoprotein-I Human Recombinant Cadherin-E Human Recombinant B2 Microglobin Cadherin-N Human Recombinant B2 Microglobin Human Recombinant Calbindin D-28K Rat Recombinant Baculoviral IAP Repeat-Containing 7 Human Recombinant Calbindin D-29K Human Recombinant BAD Human Recombinant Calbindin D-9K Rat Recombinant BAFF (BLyS) Human Recombinant Calcium and Integrin Binding 1 Human Recombinant BAFF (BLyS) Human Recombinant, His tag Calmodulin Human Recombinant BAFF (BLyS) Receptor Human Recombinant Calmodulin-2 Human Recombinant Batroxobin Recombinant Calretinin Mouse Recombinant Bax Mouse Recombinant Calsequestrin Bax Mouse Recombinant, GST Tag Calumenin Human Recombinant BCA-1/ BLC (CXCL13) Human Recombinant Camp Responsive Element Binding Protein Human Recombinant Bcl2 Modifying Factor, Isoform 3 Human Recombinant Capric Acid, Conjugated (Cat. #AG-092) Beta Defensin -1 Human Recombinant Caproic Acid, Conjugated (Cat. #AG-090) Beta Defensin -2 Human Recombinant Caprylic Acid, Conjugated (Cat. #AG-091) Beta Defensin -3 Human Recombinant Carbonic Anhydrase 2 Human Recombinant Beta Defensin -4 Human Recombinant Carbonic Anhydrase II E.Coli Recombinant Beta Lactamase Recombinant Carbonic Anhydrase III Human Recombinant beta Nerve Growth Factor Human Recombinant Carbonyl Reductase-1 Human Recombinant beta Nerve Growth Factor Human Recombinant, CHO Carcinoembryonic Antigen Human Recombinant beta Nerve Growth Factor Mouse Cardiac Actin beta Nerve Growth Factor Mouse Recombinant Cardiotrophin-1 Human Recombinant Beta-Alanine, Conjugated (Cat. #AG-020) Carnosine, Conjugated (Cat. #AG-063) Beta-Site APP-Cleaving Enzyme 1 Human Recombinant Casein Kinase 2 alpha Human Recombinant Beta-Synuclein Human Recombinant Casein Kinase 2 beta Human Recombinant Beta-Trace Human Recombinant Casein Kinase 2 beta Human Recombinant, Active Betacellulin Bovine Recombinant Casein Kinase 2 Holoenzyme Human Recombinant Betacellulin Human Recombinant Caspase and RIP Adapter with Death Domain Human Recombinant Betaine-Homocysteine Methyltransferase Human Recombinant Caspase-3 Human Recombinant BH3 Interacting Domain Death Agonist Human Recombinant Catechol-O-Methyltransferase Human Recombinant BH3 Interacting Domain Death Agonist Mouse Recombinant Cathepsin-D Human Recombinant BH3 Interacting Domain Death Agonist Mouse Recombinant, GST Cathepsin-L Human Recombinant BH3 Interacting Domain Death Agonist Mouse Recombinant, p15 Caveolin-3 Human Recombinant Biliverdin Reductase B Human Recombinant Cbp/p300-Interacting Transactivator 2 Human Recombinant Bivalirudin Cbp/p300-Interacting Transactivator/MSP-1 Human Recombinant Bone Morphogenetic protein Receptor-1A Human Recombinant CCAAT/enhancer binding protein (C/EBP) Alpha Human Recombinant Bone Morphogenetic protein-2 Human Recombinant CCAAT/enhancer binding protein (C/EBP) Gamma Human Recombinant Bone Morphogenetic protein-2 Human Recombinant, CHO CCL16 Human Recombinant Bone Morphogenetic protein-2 Human Recombinant, Monomer CD11b Human Recombinant Bone Morphogenetic protein-4 Human Recombinant CD14 CHO-derived Human Recombinant Bone Morphogenetic protein-6 Human Recombinant CD14 Mouse Recombinant Bone Morphogenetic protein-7 Human Recombinant CD146 Human Recombinant Bone Morphogenetic protein-7 Human Recombinant, CHO CD147 Human Recombinant Bone Morphogenetic protein-7 Human Recombinant, His tag CD1A Human Recombinant Borrelia p41 Recombinant CD2 Human Recombinant Bovine Apo Transferrin CD23 Human Recombinant Bovine Deoxyribonuclease I CD29 Human Recombinant Bovine Endothelial Mitogen CD31 Human Recombinant Bovine Fibroblast Growth Factor-acidic CD34 Human Recombinant Bovine Holo Transferrin CD38 Human Recombinant Bovine Thrombin CD4 (125-202) Human Recombinant Bovine Vimentin CD4 (203-317) Human Recombinant BP-1 Human Recombinant CD4 (26-226) Human Recombinant Brain-Derived Neurotrophic Factor Human Recombinant CD4 (411-459) Human Recombinant BRAK (CXCL14) Human Recombinant CD4 Human Recombinant, soluble Buserelin Hormone CD40 Ligand/TRAP Human Recombinant, soluble C-10 (CCL6) Mouse Recombinant CD40 Ligand/TRAP Mouse Recombinant, soluble c-erbB2 Human Recombinant CD43 Human Recombinant C-JUN Recombinant CD45 Human Recombinant C-Reactive Protein Human CD52 Human Recombinant C-Reactive Protein Human Recombinant CD56 Human Recombinant C-SRC Human Recombinant CD68 Human Recombinant C1 Human Complement Component CD72 Human Recombinant C1q Human Complement Component (Cat. #PRP-554) CD9 Human Recombinant C1q TNF1 Human Recombinant Complement CD95 Human Recombinant, His tag C1q TNF3 Human Recombinant Complement CD99 Human Recombinant C1q TNF6 Human Recombinant Complement CDC28 protein kinase 2 Human Recombinant C1q TNF7 Human Recombinant Complement Cell Division Cycle 34 Recombinant Page 47 Proteins, Peptides & Antigens (continued) Cell Division Cycle 37 Human Recombinant Cytokeratin 8 Human Recombinant Cell Division Cycle 6 Human Recombinant Cytotoxic T-Lymphocyte Associated Antigen-4 Human Recombinant Cellular Retinoic Acid binding Protein 2 Human Recombinant D-Alanine, Conjugated (Cat. #AG-034) Centromere Protein-A Human Recombinant D-Aspartate, Conjugated (Cat. #AG-021) Centromere Protein-B Human Recombinant D-Biotin, Conjugated (Cat. #AG-088) Cetrorelix Hormone D-Cysteine, Conjugated (Cat. #AG-036) Chimeric Chagas Multiantigen Recombinant (Cat. #PRP-001) D-Glutamate, Conjugated (Cat. #AG-026) Chlamydia Trachomatis HSP70 (462-503) Recombinant D-Methionine, Conjugated (Cat. #AG-093) Chlamydia Trachomatis HSP70 (549-660) Recombinant D-Pantothenic Acid, Conjugated (Cat. #AG-089) Chlamydia Trachomatis PGP3-D Recombinant D-Serine, Conjugated (Cat. #AG-052) Chlamydia Trachomatis W2 Recombinant D-Tryptophan, Conjugated (Cat. #AG-097) Chlamydia Trachomatis W3-W6 Recombinant D-Tyrosine, Conjugated (Cat. #AG-103) Chlamydia Trachomatis W4 Recombinant D4-GDI Human Recombinant Chlamydia Trachomatis W4-W5 Recombinant DDIT3 GST tag Human Recombinant Chlamydia Trachomatis W5 Recombinant DDIT3 Human Recombinant Chlamydia Trachomatis W5-W6 Recombinant Dengue Envelope C-Terminal Peptide Recombinant (Cat. #PRP-006) Chromagranin A Human Recombinant Dengue Envelope ST1 Recombinant (Cat. #PRP-005) Chromogranin A Human Recombinant Dengue Envelope ST2 Recombinant (Cat. #PRP-007) Chromogranin A Human Recombinant, His tag Dengue Envelope ST3 Recombinant (Cat. #PRP-008) Chromosome 19 Open Reading Frame 10 Human Recombinant Dengue Envelope ST4 Recombinant (Cat. #PRP-009) Ciliary Neurotrophic Factor Human Recombinant Dengue NS1 Recombinant (Cat. #PRP-404) Ciliary Neurotrophic Factor Human Recombinant, His tag Dengue NS1c Recombinant Ciliary Neurotrophic Factor Rat Recombinant Dengue NS1n Recombinant CMV gB Recombinant Dengue NS3 Recombinant CMV Mosaic Recombinant Dengue Polyvalent Recombinant (Cat. #PRP-410) CMV Pp150 Recombinant Deoxyribonuclease I Human Recombinant CMV Pp28 Recombinant Der F1 Protein Recombinant CMV Pp38 Recombinant Der P1 Protein Recombinant CMV Pp52 Recombinant Desert HedgeHog Human Recombinant CMV Pp65 Recombinant Deslorelin Cofilin-1 Human Recombinant Desmin Human Recombinant Collagen Human Recombinant Desmopressin Hormone Collagen-1 Human Recombinant Diamino-Pentane, Conjugated (Cat. #AG-064) Collagen-3 Human Recombinant Dickkopf-Related Protein 1 Human Recombinant Collagen-VI Human Recombinant Dimethylglycine oxidase Recombinant Collapsin Response Mediator Protein-1 Human Recombinant Dipeptidyl-Peptidase 4 Human Recombinant Connective Tissue Growth Factor Human Recombinant Dipeptidyl-Peptidase 4, Human Connective Tissue Growth Factor Human Recombinant, (182-250aa) DJ-1 Human Recombinant Connective Tissue Growth Factor Human Recombinant, His tag DL-Citrulline, Conjugated (Cat. #AG-070) Creatine Kinase BB Isoenzyme Human Recombinant DnaJ (HSP40) Human Recombinant Creatine Kinase MB Isoenzyme Type-1 Human Recombinant DnaJ Recombinant Creatine Kinase MB Isoenzyme Type-2 Human Recombinant Dnak (HSP70) E.Coli Recombinant Creatine Kinase MM Dnak (HSP70) Human Recombinant Creatine Kinase MM Isoenzyme Type-1 Human Recombinant Dnak (HSP70) Human Recombinant, His tag Creatine Kinase MM Isoenzyme Type-3 Human Recombinant Dnak ATPase Binding Domain E.Coli Recombinant Crystallin Alpha A Human Recombinant Dnak Lid Covering Substrate E.Coli Recombinant Crystallin Alpha B Human Recombinant Dnak Substrate Binding Domain E.Coli Recombinant Crystallin Alpha B Mouse Recombinant Dnak Substrate Binding Domain E.Coli Recombinant, C-terminal Cyclin-C Human Recombinant Dopa Decarboxylase Human Recombinant Cyclin-Dependent Kinase 4 Human Recombinant Dopamine, Conjugated (Cat. #AG-001) Cyclin-Dependent Kinase 8 Human Recombinant Down Syndrome Critical Region 1 Human Recombinant Cyclin-Dependent Kinase Inhibitor 2A Human Recombinant Drosophila melanogaster GAGA-POZ Recombinant Cyclophilin-A Human Recombinant DsbA (Disulfide Oxidoreductase) Recombinant Cyclophilin-B Human Recombinant DsbC (Disulfide Bond Isomerase) Recombinant Cyclophilin-D Human Recombinant DsbE (Thiol Disulfide Interchange Protein) E.Coli Recombinant Cyclophilin-E Human Recombinant DsbG (Thiol Disulfide Interchange Protein) E.Coli Recombinant Cyclophilin-F Human Recombinant dUTPase Thermostable Recombinant Cyclophilin-H Human Recombinant Dystrobrevin-Binding Protein 1 Isoform C Human Recombinant Cyclosporine-A E-Selectin Human Recombinant Cystatin C Human EBAG9 Human Recombinant Cystatin C Human Recombinant EBV (HHV-4) EA Recombinant Cystatin C Rat Recombinant (Cat. #PRP-438) EBV (HHV-4) EBNA1 Recombinant, His tag Cystatin-B Human Recombinant EBV (HHV-4) Mosaic EBNA1 Recombinant Cystatin-C Mouse Recombinant EBV (HHV-4) Mosaic p18 Recombinant Cytochrome P450 2D6 Human Recombinant EBV (HHV-4) p18 GST Recombinant Cytokeratin 14 Human Recombinant EBV (HHV-4) p18 Recombinant Cytokeratin 18 Human Recombinant EBV (HHV-4) p23 Recombinant Cytokeratin 18 Human Recombinant, His tag EBV (HHV-4) p23 Recombinant, His Cytokeratin 19 Human Recombinant Elcatonin Hormone Cytokeratin 20 Human Recombinant Eledoisin Page 48 Proteins, Peptides & Antigens (continued) ELK-1 Human Recombinant Fatty Acid Binding Protein-5 Human Recombinant, His tag Encephalitis Virus, Japanese Recombinant Fatty Acid Binding Protein-6 Human Recombinant Encephalitis Virus, Tick-Borne CE/gE Recombinant Fatty Acid Binding Protein-6 Human Recombinant, His tag Encephalitis Virus, Tick-Borne Core Recombinant Fatty Acid Binding Protein-7 Human Recombinant Encephalitis Virus, Tick-Borne gE C-end Recombinant Fatty Acid Binding Protein-7 Human Recombinant, His tag Encephalitis Virus, Tick-Borne gE middle Recombinant Ferric Uptake Regulator E.Coli Recombinant Encephalitis Virus, Tick-Borne gE Recombinant Ferritin Encephalitis Virus, Tick-Borne NE/gE Recombinant Ferritin Heavy Chain Human Recombinant Encephalitis Virus, Tick-Borne NE/GE/CE/gE Recombinant Ferritin Light Chain Human Recombinant Encephalitis Virus, Tick-Borne NS3 Recombinant Fetuin Encephalitis Virus, Tick-Borne PreM Recombinant Fibroblast Growth Factor 12 Human Recombinant Endoglin Human Recombinant Fibroblast Growth Factor Receptor-1 Human Recombinant Endoglin Mouse Recombinant Fibroblast Growth Factor Receptor-2 Human Recombinant Endoglin, Sf9 Human Recombinant Fibroblast Growth Factor Receptor-3 Human Recombinant Endostatin Human Recombinant Fibroblast Growth Factor Receptor-4 Human Recombinant Endothelial-Monocyte Activating Polypeptide II Human Recombinant Fibroblast Growth Factor-19 Human Recombinant Enfuvirtide T-20 Fibroblast Growth Factor-21 Bovine Recombinant Enolase Human Recombinant, Neuronal-specific Fibroblast Growth Factor-21 Human Recombinant Enolase Human Recombinant, Neuronal-specific His tag Fibroblast Growth Factor-21 Human Recombinant, His tag Enolase, Neurone-specific Fibroblast Growth Factor-21 Mouse Recombinant Enteropeptidase/Enterokinase Fibroblast Growth Factor-21 Mouse Recombinant, His tag Enteropeptidase/Enterokinase Bovine Recombinant Fibroblast Growth Factor-22 Human Recombinant Enteropeptidase/Enterokinase, Light Chain Human Recombinant Fibroblast Growth Factor-23 Human Recombinant Eotaxin (CCL11) Human Recombinant Fibroblast Growth Factor-9 Human Recombinant Eotaxin (CCL11) Human Recombinant, His tag Fibroblast Growth Factor-9 Mouse Recombinant Eotaxin (CCL11) Mouse Recombinant Fibroblast Growth Factor-9 Rat Recombinant Eotaxin-2 (CCL24) Human Recombinant Fibroblast Growth Factor-acidic Human Recombinant Ephrin A1 Human Recombinant Fibroblast Growth Factor-acidic Human Recombinant, Sf9 Ephrin A4 Human Recombinant Fibroblast Growth Factor-acidic Mouse Recombinant Ephrin B1 Human Recombinant Fibroblast Growth Factor-basic Bovine Ephrin B3 Human Recombinant Fibroblast Growth Factor-basic Bovine Recombinant Epidermal Growth Factor (Leu 21) Human Recombinant Fibroblast Growth Factor-basic Human Recombinant Epidermal Growth Factor Human Recombinant Fibroblast Growth Factor-basic Human Recombinant (147) Epidermal Growth Factor Mouse Fibroblast Growth Factor-basic Human Recombinant, Sf9 Epidermal Growth Factor Mouse Recombinant Fibroblast Growth Factor-basic Mouse Recombinant Epidermal Growth Factor Rat Fibroblast Growth Factor-basic Rat Recombinant Epidermal Growth Factor Receptor Human Recombinant, Sf9 Fibronectin Epidermal Growth Factor Receptor-Sf9 Human Recombinant Filaggrin Human Recombinant Epidermal Growth Factor, Pichia Human Recombinant Filamin Epigen Human Recombinant FK506 Binding Protein 1A Human Recombinant Epiregulin Human Recombinant FK506 Binding Protein 4 Human Recombinant Epithelial Neutrophil-Activating Protein 78 (CXCL5) Human Recombinant Flt3-Ligand Human Recombinant Epstein Barr Virus Induced 3 Mouse Recombinant Flt3-Ligand Mouse Recombinant Eptifibatide Flt3-Ligand Sf9 Human Recombinant ERK1/MAPK3 Active Enzyme Human Recombinant Focal Adhesion Kinase 1 Human Recombinant ERK1/MAPK3 Inactive Enzyme Human Recombinant Folic acid, Conjugated (Cat. #AG-094) ERK2/MAPK1 Active Enzyme Human Recombinant Follicle Stimulating Hormone ERK2/MAPK1 Inactive Enzyme Human Recombinant Follicle Stimulating Hormone Human Recombinant Erythropoietin-alpha Fc/Chimera Human Recombinant Follistatin Human Recombinant Erythropoietin-alpha Human Recombinant Formaldehyde, Conjugated (Cat. #AG-060) Estrogen Receptor Alpha Human Recombinant Formic Acid, Conjugated (Cat. #AG-040) Estrogen Sulfotransferase Human Recombinant Formiminotransferase Cyclodeaminase Human Recombinant Ets-1 Human Recombinant (Cat. #PRP-501) FOS-B Human Recombinant Eukaryotic Initiation Factor 2-alpha Human Recombinant Fractalkine (CX3CL1 Human Recombinant Exenatide Hormone Fragile Histidine Triad Human Recombinant Exendin-4 Recombinant Fumarate Hydratase Human Recombinant Exodus-2 (CCL21) Human Recombinant Fyn-p59 Human Recombinant Factor IX G CSF Human Recombinant Factor VIIa Human Recombinant G CSF Human Recombinant, CHO Factor VIII G CSF Human Recombinant, His tag Factor VIII Human Recombinant G CSF Mouse Recombinant Factor VIII Human Recombinant, Related Antigen GABA (Gamma-Aminobutyric acid), Conjugated (Cat. #AG-023) Fatty Acid Binding Protein-1 Human Recombinant Galectin-1 Human Recombinant Fatty Acid Binding Protein-1 Human Recombinant, His tag Galectin-3 Human Recombinant Fatty Acid Binding Protein-2 Human Recombinant Gamma-Synuclein Human Recombinant Fatty Acid Binding Protein-3 Human Recombinant Ganciclovir Fatty Acid Binding Protein-3 Human Recombinant, His tag Ganirelix Fatty Acid Binding Protein-4 Human Recombinant Gankyrin Human Recombinant Fatty Acid Binding Protein-4 Human Recombinant, His tag Gelatin Human Recombinant Fatty Acid Binding Protein-5 Human Recombinant Geminin Human Recombinant Page 49 Proteins, Peptides & Antigens (continued) GHRL Hormone Growth Hormone Human Recombinant GHRP-2 Hormone Growth Hormone Mai Mai Recombinant GHRP-6 Hormone Growth Hormone Mouse Recombinant Gibberellic Acid, Conjugated (Cat. #AG-108) Growth Hormone Ovine Recombinant GLC8 Yeast Recombinant Growth Hormone Ovine Recombinant, Antagonist Glia Maturation Factor Human Recombinant, beta Growth Hormone Ovine Recombinant, Placental Glia Maturation Factor Human Recombinant, gamma Growth Hormone Porcine Recombinant Glial Filament Protein Growth Hormone Rabbit Recombinant Glial-Derived Neurotrophic Factor Human Recombinant Growth Hormone Rat Recombinant Glomerular Basement Membrane Human Recombinant Growth Hormone-Releasing Hormone Glucagon Haptoglobin Glucagon Human Recombinant Haptoglobin Human Recombinant Glucagon Like Peptide-1 (7-36) Human HAV P2C Recombinant (Cat. #PRP-229) Glucagon Like Peptide-1 (7-36) Human Recombinant HAV P2C-P3A Recombinant (Cat. #PRP-266) Glucose-6-Phosphate Dehydrogenase Human Recombinant HAV P2C-P3B Recombinant (Cat. #PRP-230) Glutaredoxin 1 Human Recombinant HAV P3C Recombinant (Cat. #PRP-231) Glutaredoxin 1 Yeast Recombinant HAV VP1 Recombinant (Cat. #PRP-227) Glutaredoxin 2 Yeast Recombinant HAV VP1-P2A (669-782aa) Recombinant (Cat. #PRP-265) Glutathione S-Transferase M1 Mouse Recombinant HAV VP1-P2A (722-830aa) Recombinant (Cat. #PRP-228) Glutathione S-Transferase Recombinant HAV VP3 Recombinant (Cat. #PRP-226) Glutathione, Conjugated (Cat. #AG-058) HAV VP4-VP2 Recombinant (Cat. #PRP-225) Glyceraldehyde-3-Phosphate Dehydrogenase Human Recombinant HBcAg Delta Recombinant Glycine N-Methyltransferase Human Recombinant HBcAg Recombinant (183) Glycine, Conjugated (Cat. #AG-024) HBcAg Recombinant (186) Glycogen Phosphorylase Human Recombinant HBeAg Recombinant Glyoxalase-I Human Recombinant HBsAg adr Recombinant GM CSF Human Recombinant HBsAg adr Recombinant, CHO GM CSF Human Recombinant, His tag HBsAg adw Recombinant GM CSF Human Recombinant, Pichia HBsAg adw Saccharomyces Recombinant GM CSF Human Recombinant, Sf9 HBsAg ayw Recombinant GM CSF Mouse Recombinant HBsAg ayw Recombinant, Pichia GM CSF Porcine Recombinant HBsAg preS1 Recombinant GM CSF Rat Recombinant HBsAg preS2 Recombinant GM CSF/IL-3 Fusion Protein (PIXY321) Human Recombinant HBV HBe Recombinant Goserelin Hormone HBV X Recombinant Green Fluorescent Protein Recombinant HCC-1 (CCL14) Human Recombinant GRO-alpha (CXCL1) Human Recombinant HCG Hormone GRO-alpha (CXCL1) Human Recombinant, His tag HCV Combined Recombinant GRO-beta/MIP-2 (CXCL2) His Human Recombinant HCV Core 22kDa Recombinant GRO-beta/MIP-2 (CXCL2) Human Recombinant HCV Core 22kDa Recombinant, Biotin GRO-beta/MIP-2 Mouse Recombinant HCV Core 22kDa Recombinant, Fluorescein GRO-beta/MIP-2 Rat Recombinant HCV Core 22kDa Recombinant, Rhodamine GRO-gamma (CXCL3) Human Recombinant HCV Core Genotype-1 Recombinant GRO-gamma (CXCL3) Human Recombinant, His tag HCV Core Genotype-1a Recombinant GRO/KC Mouse Recombinant HCV Core Genotype-1b Recombinant GroEL (HSP60) Human Recombinant HCV Core Genotype-2a Recombinant (Cat. #PRP-214) GroEL (HSP60) Recombinant, E. Coli HCV Core Genotype-2b Recombinant (Cat. #PRP-237) GroES (HSP10) Human Recombinant HCV Core Genotype-3/10 Recombinant GroES (HSP10) Recombinant, E. Coli HCV Core Genotype-3a Recombinant Gross Cystic Disease Fluid Protein-15 Human Recombinant HCV Core Genotype-3b Recombinant Growth and Differentiation factor 10 Human Recombinant HCV Core Genotype-4 Recombinant (Cat. #PRP-216) Growth and Differentiation factor 5 Human Recombinant HCV Core Genotype-5 Recombinant Growth and Differentiation factor 5 Human Recombinant, His tag HCV Core Genotype-6a Recombinant Growth Arrest and DNA-Damage-Inducible Beta Human Recombinant HCV Core Recombinant (105-302) Growth Arrest and DNA-Damage-Inducible Gamma Human Recombinant HCV Core Recombinant, Biotin Growth Arrest-Specific 7, Isoform b Human Recombinant HCV Core Recombinant, HRP Growth Factor Receptor-Bound Protein 2 Human Recombinant HCV Core-24 Recombinant Growth Hormone 20kDa Human Recombinant, Pituitary HCV NS3 Genotype-1a Recombinant (1192-1459) (Cat. #PRP-246) Growth Hormone 20kDa Human Recombinant, Placental HCV NS3 Genotype-1a Recombinant (1356-1459) Growth Hormone 22kDa Human Recombinant, Placental HCV NS3 Genotype-1b Recombinant Growth Hormone Binding Protein Bovine Recombinant HCV NS3 Genotype-1b Recombinant (1192-1459) Growth Hormone Binding Protein Human Recombinant HCV NS3 Genotype-1b Recombinant (1356-1459) Growth Hormone Binding Protein Ovine Recombinant HCV NS3 Genotype-1c Recombinant Growth Hormone Binding Protein Rabbit Recombinant HCV NS3 Genotype-2b Recombinant (1192-1459) Growth Hormone Bovine Recombinant HCV NS3 Genotype-2b Recombinant (1356-1459) Growth Hormone Carp Recombinant HCV NS3 Genotype-2c Recombinant (1192-1459) Growth Hormone Chicken Recombinant HCV NS3 Genotype-2c Recombinant (1356-1459) Growth Hormone Chicken Recombinant, Anatagonist HCV NS3 Genotype-3 Recombinant Growth Hormone Denis Recombinant HCV NS3 Genotype-4 Recombinant Growth Hormone Gilthead Seabream Recombinant HCV NS3 Genotype-5 Recombinant (1192-1459) Page 50 Proteins, Peptides & Antigens (continued) HCV NS3 Genotype-5 Recombinant (1356-1459) Histamine N-Methyltransferase Human Recombinant HCV NS3 Genotype-5a Recombinant Histamine, Conjugated (Cat. #AG-027) HCV NS3 Genotype-6 Recombinant Histidine NADH Dehydrogenase Fe-S Protein 4 Human Recombinant HCV NS3 Genotype-6a Recombinant Histidine Triad Nucleotide Binding Protein 1 Human Recombinant HCV NS3 Recombinant Histidyl-tRNA Synthetase Human Recombinant (Cat. #PRP-268) HCV NS3 Recombinant, Biotin Histidyl-tRNA Synthetase Human Recombinant, Sf9 HCV NS3 Recombinant, HRP Histone Deacetylase 1 Human Recombinant HCV NS4 a+b Recombinant Histrelin Hormone HCV NS4 a+b Recombinant, Biotin HIV Type O Envelope Recombinant HCV NS4 a+b Recombinant, Fluorescein HIV Type O gp41 Recombinant HCV NS4 a+b Recombinant, Rhodamine HIV Type O gp41 Recombinant, MBP tag HCV NS4 Genotype-1 Recombinant HIV-1 Envelope Recombinant (233) HCV NS4 Genotype-2 Recombinant HIV-1 Envelope Recombinant, His tag HCV NS4 Genotype-3 Recombinant HIV-1 gag p17-p24, gp41-gp120 Recombinant (Cat. #PRP-110) HCV NS4 Genotype-5 Recombinant HIV-1 gag p17, p24 Recombinant (Cat. #PRP-121) HCV NS4 Mosaic Recombinant HIV-1 gag p17, p24, gp120 Recombinant (Cat. #PRP-111) HCV NS4 Recombinant HIV-1 gag p24 Recombinant (Cat. #PRP-123) HCV NS4 Recombinant, HRP HIV-1 gag p24 Recombinant, His Tag (Cat. #PRP-149) HCV NS5 Genotype-1 Recombinant HIV-1 gag p55 Recombinant HCV NS5 Genotype-1a Recombinant HIV-1 gp120 CM Recombinant HCV NS5 Genotype-1a Recombinant (2322-2423) HIV-1 gp120 LAV Recombinant HCV NS5 Genotype-1b Recombinant HIV-1 gp120 MN Recombinant HCV NS5 Genotype-2 Recombinant HIV-1 gp120 Recombinant HCV NS5 Genotype-2a Recombinant HIV-1 gp160 LAV Recombinant HCV NS5 Genotype-2b Recombinant HIV-1 gp160 MN Recombinant HCV NS5 Genotype-3 Recombinant HIV-1 gp41 Long Recombinant HCV NS5 Genotype-3a Recombinant HIV-1 gp41 Long Recombinant, Biotin HCV NS5 Genotype-3b Recombinant HIV-1 gp41 Long Recombinant, HRP HCV NS5 Genotype-4 Recombinant HIV-1 gp41 Recombinant HCV NS5 Genotype-5 Recombinant HIV-1 gp41 Recombinant, Biotin HCV NS5 Genotype-6 Recombinant HIV-1 gp41 Recombinant, His tag HCV NS5 Genotype-6a Recombinant HIV-1 gp41 Recombinant, HRP HCV NS5 Recombinant HIV-1 gp41 Recombinant, MBP tag HCV NS5 Recombinant, Biotin HIV-1 Integrase Recombinant, p31 HCV NS5 Recombinant, HRP HIV-1 Integrase Recombinant, pol HDV Recombinant HIV-1 Nef Recombinant Heat Shock Factor Binding Protein- 1 Human Recombinant HIV-1 Nef Recombinant, Clade B Heat Shock Protein 104 Human Recombinant HIV-1 p24 Biotin Recombinant Heat Shock Protein 105 Human Recombinant HIV-1 p24 Recombinant Heat Shock Protein 20 Human Recombinant HIV-1 p24 Recombinant, 24kDa Heat Shock Protein 22 Human Recombinant HIV-1 p24 Recombinant, Biotin-labeled (Cat. #PRP-106) Heat Shock Protein 27 Human Recombinant HIV-1 p24c Recombinant Heat Shock Protein 47 Human Recombinant HIV-1 p24c Recombinant, Sf9 Heat Shock Protein 5 Human Recombinant HIV-1 p66 Recombinant, pol Heat Shock Protein 65 Human Recombinant HIV-1 TAT Cys22 Recombinant Heat Shock Protein 9 Human Recombinant HIV-1 TAT Recombinant, Biotin Heat Shock Protein 90 Alpha Human Recombinant HIV-1 TAT Recombinant, Clade A Heat Shock Protein 90kDa Beta (GRP94) Member 1 Human Recombinant HIV-1 TAT Recombinant, Clade B Heat Shock Protein Cofactor 70 (HSP24) Recombinant, E. Coli HIV-1 TAT Recombinant, Clade C Heat Shock Transcription Factor-1 Human Recombinant HIV-1 TAT Recombinant, Clade D Heme Oxygenase 1 Human Recombinant HIV-1,2 Recombinant Hemoglobin A1c HIV-2 Envelope Recombinant Hemopexin HIV-2 gp32 Recombinant Heparanase-1 Human Recombinant HIV-2 gp32 Recombinant, Biotin Hepatocyte Growth Factor, CHO Human Recombinant HIV-2 gp32 Recombinant, HRP Hepatocyte Growth Factor, Sf9 Human Recombinant HIV-2 gp36 Recombinant Hepatocyte-Promoting Growth Factor Porcine HIV-2 gp36 Recombinant (390-702) HEV ORF2 Recombinant (403-461) HIV-2 gp36 Recombinant, His tag HEV ORF2 Recombinant (452-617) HIV-2 gp36 Recombinant, MBP tag HEV ORF2 Recombinant (633-659) HMGB1 Human Recombinant (Cat. #PRP-581) HEV ORF2/ORF3 Recombinant, 33 kDa HMGB1 Human Recombinant, Sf9 (Cat. #PRP-610) HEV ORF2/ORF3 Recombinant, 38.5 kDa HMTase Human Recombinant HEV ORF3 Recombinant Holo Transferrin Hexarelin Hormone Homer Homolog-1 Human Recombinant Hexokinase-1 Human Recombinant Homocysteic Acid, Conjugated (Cat. #AG-029) Hexokinase-2 Human Recombinant Homocysteine, Conjugated (Cat. #AG-028) Hexokinase-3 Human Recombinant Homovanillic Acid, Conjugated (Cat. #AG-039) Hexokinase-4 Human Recombinant Horseradish Peroxidase High Density Lipoprotein HRAS-Like Suppressor 3 Human Recombinant Hirudin Recombinant HSA Mammalian-Derived Recombinant Page 51 Proteins, Peptides & Antigens (continued) HSA Recombinant Insulin, Porcine HSA, Plant Recombinant Intercellular Adhesion Molecule-1 Human Recombinant HSP70 Interacting Protein Human Recombinant Interferon Regulatory Factor-1 Human Recombinant HSP90 ATPase-1 Human Recombinant Activator Interferon Regulatory Factor-2 Human Recombinant HSV-1 gD Recombinant Interferon Regulatory Factor-3 Human Recombinant HSV-1 gG Recombinant Interferon Regulatory Factor-4 / MUM-1 Human Recombinant HSV-2 gD Recombinant Interferon Stimulated Gene 15 Human Recombinant HSV-2 gG Recombinant Interferon-alpha 1 Human Recombinant HSV-8 Mosaic Recombinant Interferon-alpha 1a Human Recombinant HTLV 1+2 Recombinant Interferon-alpha 1b Human Recombinant HTLV-1 Envelope Recombinant Interferon-alpha 2a Human Recombinant HTLV-1 gp21 Recombinant Interferon-alpha 2a Human Recombinant, Tobacco HTLV-1 gp46 Recombinant Interferon-alpha 2b Human Recombinant HTLV-1 Mosaic Recombinant Interferon-alpha 2b Human Recombinant, Saccharomyces HTLV-1 p24c Recombinant Interferon-beta 1a Human Recombinant HTRA2 Human Recombinant Interferon-beta 1b Human Recombinant Human Prostate Specific Gene-1 Recombinant Interferon-beta Mouse Recombinant Human Serum Albumin Interferon-beta Mouse Recombinant, His tag Hyaluronidase Interferon-gamma Human Recombinant Hypoxia-Inducible Factor-1 Alpha Human Recombinant Interferon-gamma Human Recombinant, His tag Hypoxia-Inducible Factor-1 Alpha Inhibitor Human Recombinant Interferon-gamma Mouse Recombinant I-309 (CCL1) Human Recombinant Interferon-gamma Porcine Recombinant I-TAC (CXCL11) Human Recombinant Interferon-gamma Rat Recombinant I-TAC (CXCL11) Human Recombinant, His tag Interferon-Tau Ovine Recombinant IB4 (Cat. #PR-02) Interleukin-1 alpha Human Recombinant Ibuprofen, Conjugated (Cat. #AG-123) Interleukin-1 alpha Human Recombinant, His tag Influenza A Virus H1N1 Beijing (Cat. #PRP-002) Interleukin-1 alpha Mouse Recombinant Influenza A Virus H1N1 California (Cat. #PRP-014) Interleukin-1 alpha Porcine Recombinant Influenza A Virus H1N1 New Caledonia (Cat. #PRP-003) Interleukin-1 alpha Rat Recombinant Influenza A Virus H1N1 New Caledonia Recombinant (Cat. #PRP-030) Interleukin-1 beta Human Recombinant Influenza A Virus H1N1 Solomon Islands (Cat. #PRP-022) Interleukin-1 beta Human Recombinant, His tag Influenza A Virus H1N1 Solomon Islands Recombinant (Cat. #PRP-031) Interleukin-1 beta Mouse Recombinant Influenza A Virus H1N1 Taiwan (Cat. #PRP-037) Interleukin-1 beta Mouse Recombinant, His tag Influenza A Virus H3N2 Brisbane (Cat. #PRP-024) Interleukin-1 beta Porcine Recombinant Influenza A Virus H3N2 Kiev (Cat. #PRP-026) Interleukin-1 beta Rat Recombinant (Cat. #PRP-301) Influenza A Virus H3N2 New York (Cat. #PRP-011) Interleukin-1 Receptor Human Recombinant, Antagonist Influenza A Virus H3N2 Panama (Cat. #PRP-025) Interleukin-1 Receptor Human Recombinant, Antagonist His tag Influenza A Virus H3N2 Shandong (Cat. #PRP-004) Interleukin-1 Receptor Mouse Recombinant, Antagonist Influenza A Virus H3N2 Wisconsin (Cat. #PRP-023) Interleukin-10 Human Recombinant Influenza A Virus H3N2 Wisconsin Recombinant (Cat. #PRP-020) Interleukin-10 Human Recombinant, CHO Influenza A Virus H3N2 Wyoming (Cat. #PRP-012) Interleukin-10 Human Recombinant, His tag Influenza A Virus H5N1 Indonesia (Cat. #PRP-032) Interleukin-10 Mouse Recombinant Influenza A Virus H5N1 Vietnam (Cat. #PRP-010) Interleukin-10 Porcine Recombinant Influenza A Virus H7N7 Netherlands Recombinant Interleukin-10 Rat Recombinant Influenza A Virus H9N2 Hong Kong Recombinant Interleukin-11 Human Recombinant Influenza B Virus Florida 04/06 (Cat. #PRP-027) Interleukin-11 Mouse Recombinant Influenza B Virus Florida 07/04 (Cat. #PRP-029) Interleukin-12 Human Recombinant Influenza B Virus Jilin Recombinant (Cat. #PRP-021) Interleukin-12 p35 Human Recombinant, His tag Influenza B Virus Malaysia (Cat. #PRP-028) Interleukin-12 p40 Human Recombinant, His tag Influenza B Virus Malaysia Recombinant (Cat. #PRP-033) Interleukin-12 Rat Recombinant Influenza B Virus Ohio Recombinant (Cat. #PRP-015) Interleukin-13 Human Recombinant Influenza B Virus Qingdao (Cat. #PRP-016) Interleukin-13 Human Recombinant, His tag Influenza B Virus Tokyo (Cat. #PRP-017) Interleukin-13 Mouse Recombinant Influenza B Virus Victoria (Cat. #PRP-018) Interleukin-13 Rat Recombinant Inhibin-Alpha Human Recombinant Interleukin-15 Human Recombinant Inhibin-Alpha Human Recombinant, A Chain Interleukin-15 Human Recombinant, His tag Insulin Human Recombinant Interleukin-15 Mouse Recombinant Insulin Human Recombinant, Degrading Enzyme Interleukin-15 Mouse Recombinant, His tag Insulin Human Recombinant, Yeast Interleukin-15 Porcine Recombinant Insulin Like Growth Factor Binding Protein-1 Human Recombinant Interleukin-15 Rat Recombinant Insulin Like Growth Factor Binding Protein-3 Human Recombinant Interleukin-16 Human Recombinant Insulin Like Growth Factor Binding Protein-5 Human Recombinant Interleukin-16 Human Recombinant, His tag Insulin Like Growth Factor Binding Protein-6 Human Recombinant Interleukin-16 Mouse Recombinant Insulin Like Growth Factor-1 Gilthead Seabream Recombinant Interleukin-17 Mouse Recombinant Insulin Like Growth Factor-1 Human Recombinant Interleukin-17A Human Recombinant Insulin Like Growth Factor-1 Human Recombinant, Des (1-3) Interleukin-17A Rat Recombinant Insulin Like Growth Factor-1 Mouse Recombinant Interleukin-17A/F Heterodimer Human Recombinant Insulin Like Growth Factor-1 Rat Recombinant Interleukin-17A/F Heterodimer Mouse Recombinant Insulin Like Growth Factor-2 Human Recombinant Interleukin-17E Human Recombinant Insulin Like Growth Factor-I Receptor Human Recombinant Interleukin-17E Mouse Recombinant Page 52 Proteins, Peptides & Antigens (continued) Interleukin-17E Rat Recombinant JNK2 alpha 1 Human Recombinant Interleukin-17F Human Recombinant JNK2 alpha 2 Human Recombinant Interleukin-17F Mouse Recombinant JNK2/SAPK1 Human Recombinant Interleukin-17F Rat Recombinant Kainic Acid, Conjugated (Cat. #AG-116) Interleukin-18 Human Recombinant Kallikrein-1 Human Recombinant Interleukin-18 Mouse Recombinant KBP-Type Peptidyl-Prolyl Cis-Trans Isomerase E.Coli Recombinant Interleukin-18 Rat Recombinant Keratin-8 Human Recombinant Interleukin-19 Human Recombinant Keratinocye Growth Factor Human Recombinant Interleukin-19 Mouse Recombinant Keratinocye Growth Factor-2 Human Recombinant Interleukin-2 Human Recombinant KIR2DL1 Human Recombinant Interleukin-2 Mouse Recombinant KIR2DL3 Human Recombinant Interleukin-2 Mouse Recombinant, His tag KIR2DS4 Human Recombinant Interleukin-2 Porcine Recombinant KIR3DL1 Human Recombinant Interleukin-2 Rat Recombinant KISS-1 Metastasis-Suppressor Human Recombinant Interleukin-2 Receptor alpha Human Recombinant, soluble Ku P70/P80 Human Recombinant Interleukin-2 Receptor alpha, GST tag Human Recombinant, soluble Kynurenic Acid, Conjugated (Cat. #AG-032) Interleukin-2 Yeast Human Recombinant L-Arginine, Conjugated (Cat. #AG-019) Interleukin-20 Human Recombinant L-Asparaginase Interleukin-20 Mouse Recombinant L-Aspartate, Conjugated (Cat. #AG-043) Interleukin-21 Human Recombinant L-Cysteine, Conjugated (Cat. #AG-022) Interleukin-22 Human Recombinant L-Dihydroxyphenylalanine (L-DOPA), Conjugated (Cat. #AG-004) Interleukin-22 Mouse Recombinant L-Glutamate, Conjugated (Cat. #AG-025) Interleukin-24 Human Recombinant L-Glutamine, Conjugated (Cat. #AG-047) Interleukin-27 Mouse Recombinant L-Histidine, Conjugated (Cat. #AG-048) Interleukin-28 Human Recombinant L-Isoleucine, Conjugated (Cat. #AG-056) Interleukin-29 Human Recombinant L-Kynurenine, Conjugated (Cat. #AG-118) Interleukin-3 Human Recombinant L-Leucine, Conjugated (Cat. #AG-055) Interleukin-3 Human Recombinant, His tag L-Methionine, Conjugated (Cat. #AG-049) Interleukin-3 Human Recombinant, Sf9 L-Norephedrine, Conjugated (Cat. #AG-087) Interleukin-3 Human Recombinant, Yeast L-Phenylalanine, Conjugated (Cat. #AG-050) Interleukin-3 Mouse Recombinant L-Selectin Human Recombinant Interleukin-3 Rat Recombinant L-Serine, Conjugated (Cat. #AG-051) Interleukin-31 Human Recombinant L-Threonine, Conjugated (Cat. #AG-085) Interleukin-32 alpha Human Recombinant L-Tryptophan, Conjugated (Cat. #AG-046) Interleukin-32 alpha Human Recombinant, His tag L-Tyrosine, Conjugated (Cat. #AG-009) Interleukin-33 Human Recombinant L-Valine, Conjugated (Cat. #AG-057) Interleukin-33 Mouse Recombinant LA / SS-B Human Recombinant Interleukin-4 Human Recombinant Lactate Dehydrogenase Recombinant Interleukin-4 Human Recombinant, CHO Lactoferrin Apo Human Recombinant Interleukin-4 Human Recombinant, His tag Lactoferrin Holo Human Recombinant Interleukin-4 Mouse Recombinant (Cat. #PRP-302) Lactogen Bovine Recombinant, Placental Interleukin-4 Porcine Recombinant Lactogen Caprine Recombinant, Placental Interleukin-4 Rat Recombinant Lactogen Human Recombinant, Placental Interleukin-5 Human Recombinant Lactogen Ovine Recombinant, Placental Interleukin-5 Rat Recombinant Lambda Light Chain Interleukin-6 Human Recombinant Lamin-A Recombinant Interleukin-6 Human Recombinant, CHO Lanreotide Hormone Interleukin-6 Human Recombinant, His tag Latexin Human Recombinant Interleukin-6 Mouse Recombinant Lecithin-Cholesterol Acyltransferase Human Recombinant Interleukin-6 Porcine Recombinant Lectin Interleukin-6 Rat Recombinant Leptin Binding Domain Chicken Recombinant Interleukin-6 Receptor alpha Human Recombinant, soluble Leptin Binding Domain Human Recombinant Interleukin-7 Human Recombinant Leptin Bovine Recombinant Interleukin-7 Human Recombinant, His tag Leptin Chicken Recombinant Interleukin-7 Human Recombinant, Saccharomyces Leptin Dog Recombinant Interleukin-7 Mouse Recombinant Leptin Horse Recombinant Interleukin-8 (1-72) Porcine Recombinant Leptin Human Recombinant Interleukin-8 Human Recombinant (1-72) Leptin Human Recombinant, His tag Interleukin-8 Human Recombinant (1-77) Leptin Human Recombinant, Quadruple Antagonist Interleukin-8 Human Recombinant (1-77), His tag Leptin Human Recombinant, Triple Antagonist Interleukin-8 Human Recombinant (1-77), Pichia Leptin Mouse Recombinant Interleukin-9 Human Recombinant Leptin Mouse Recombinant, Pegylated Interleukin-9 Mouse Recombinant Leptin Mouse Recombinant, Triple Antagonist Intrinsic Factor Human Recombinant Leptin Mouse Recombinant, Triple Antagonist Pegylated Involucrin Human Recombinant Leptin Ovine Recombinant IP-10 Human Recombinant Leptin Ovine Recombinant, MTS tag IP-10 Human Recombinant, His tag Leptin Ovine Recombinant, Quadruple Antagonist IP-10 Mouse Recombinant Leptin Ovine Recombinant, Triple Antagonist IPP-POZ Human Recombinant Leptin Porcine Recombinant Isocitrate Dehydrogenase Recombinant Leptin Pufferfish Recombinant Page 53 Proteins, Peptides & Antigens (continued) Leptin Rabbit Recombinant MIF Human Recombinant Leptin Rat Recombinant MIF Human Recombinant (Active) Leptin Rat Recombinant, Pegylated MIF Human Recombinant, His C (Cat. #PRP-521) Leptin Rat Recombinant, Triple Antagonist MIF Human Recombinant, His N Leptin Rat Recombinant, Triple Antagonist Pegylated MIG (CXCL9) Human Recombinant Leukemia Inhibitory Factor Human Recombinant MIG Mouse Recombinant Leukemia Inhibitory Factor Mouse Recombinant MIP-1a (CCL3) Human Recombinant (Cat. #PRP-233) LeukinFeron MIP-1a (CCL3) Human Recombinant, His Tag (Cat. #PRP-347) Leukocyte Function Associated Antigen-3 Fusion Protein Human Recombinant MIP-1a Mouse Recombinant Leukocyte-Associated Ig-Like Receptor 1 Human Recombinant MIP-1a Rat Recombinant Leuprolide Hormone MIP-1b (CCL4) Human Recombinant Leutenizing Hormone Releasing Hormone Human Recombinant MIP-1b Mouse Recombinant Leutenizing Hormone-Releasing Hormone MIP-3a (CCL20 Human Recombinant Limulus Antilipopolysaccharide Factor Recombinant MIP-3a Mouse Recombinant Lipopolysaccarid Binding Protein Mouse Recombinant MIP-3b (CCL19 Human Recombinant Lipopolysaccarid-Binding Protein Human Recombinant MIP-3b Mouse Recombinant Listeriolysin-O PEST-free Recombinant MIP-4 (CCL18) Human Recombinant Listeriolysin-O Recombinant MIP-5 (CCL15) Human Recombinant Low Density Lipoprotein Mitogen Activated Kinase Kinase 1 Human Recombinant Lymphotactin (XCL1) Human Recombinant Modified Affinity Purified Avidin Lymphotactin (XCL1) Human Recombinant, His tag Mouse Leukemia Virus Reverse Trancscriptase Molony Recombinant Lypressin Hormone Mucosae-Associated Epithelial Chemokine (CCL28) Human Recombinant Lysostaphin Recombinant MutL Homolog-1 Human Recombinant Lysozyme Human Recombinant Mycobacterium Tuberculosis major secretory protein Antigen 85B Recombinant LYVE1 Human Recombinant Myelin Oligodendrocyte Glycoprotein LYVE1 Human Recombinant (25-235aa) Myelin Oligodendrocyte Glycoprotein Human Recombinant LYVE1 Human Recombinant, Sf9 Myeloperoxidase Human Recombinant LYVE1 Mouse Recombinant, Sf9 Myoblast Determination Protein 1 Human Recombinant M CSF Human Recombinant Myogenic Factor-4 Human Recombinant M CSF Mouse Recombinant Myoglobin M CSF Mouse Recombinant, Baculovirus Myoglobin Human Recombinant m-Calpain Myoglobin Human Recombinant, Heme free MAGE-1 Human Recombinant Myosin Light Chain 2 Human Recombinant Malaria Cs Mosaic Recombinant Myostatin Human Recombinant Malaria Protein HSP Recombinant Myostatin Human Recombinant, His tag Malate Dehydrogenase Recombinant Myostatin Propeptide Human Recombinant Malondialdehyde, Conjugated (Cat. #AG-031) Myristic Acid, Conjugated (Cat. #AG-099) Mammaglobin Human Recombinant N-Acetyl-Cysteine, Conjugated (Cat. #AG-054) Matlose Binding Protein Human Recombinant N-Acetyltransferase 6 Human Recombinant Matrix Metalloproteinase-13 Human Recombinant Nafarelin Hormone Matrix Metalloproteinase-3 Human Recombinant NAP-2 (CXCL7) Human Recombinant Matrix Metalloproteinase-7 Human Recombinant Natural Cytotoxicity Receptor NKp46 Human Recombinant Matrix Metalloproteinase-8 Human Recombinant NCK2 Human Recombinant MCP-1 Human Recombinant (CCL2), His Tag (Cat. #PRP-270) NEDD8 Human Recombinant MCP-1 Mouse Recombinant Neuregulin-1/Heregulin-b2 Human Recombinant MCP-1 Rat Recombinant Neurofilament-160kDa, Bovine MCP-1/MCAF (CCL2) Human Recombinant Neuroglobin Human Recombinant MCP-2 (CCL8) Human Recombinant Neurotrophin-3 Human Recombinant MCP-2 (CCL8) Mouse Recombinant Neurotrophin-4 Human Recombinant MCP-3 (CCL7) Human Recombinant Neutrophil Gelatinase Associated Lipocalin/Lipocalin-2 Human Recombinant MCP-3 (CCL7) Mouse Recombinant New York Esophageal Squamous Cell Carcinoma Human Recombinant MCP-4 (CCL13) Human Recombinant Nicotinamide, Conjugated (Cat. #AG-110) Measles (1-51) Recombinant Nicotineamide N-methyltransferase Human Recombinant Measles (399-525) Recombinant NO-Acetyl Salicylic Acid, Conjugated (Cat. #AG-084) Measles Mosaic (1-30,115-150,379-410) Recombinant NO-Cysteine, Conjugated (Cat. #AG-002) Measles Mosaic (106-114,519-550) Recombinant NO-Dopamine, Conjugated (Cat. #AG-081) Measles Nucleocapsid Recombinant NO-Glutathione, Conjugated (Cat. #AG-076) Measles Polymerase (2056-2183) Recombinant NO-Histidine, Conjugated (Cat. #AG-074) Measles Polymerase (58-149) Recombinant NO-L-Asparagine, Conjugated (Cat. #AG-083) Melanoma (gp100) Human Recombinant NO-L-DOPA, Conjugated (Cat. #AG-082) Melanoma Inhibitory Activity Protein 2 Human Recombinant NO-L-Glutamine, Conjugated (Cat. #AG-077) Melanoma Inhibitory Activity Protein Human Recombinant NO-L-Methionine, Conjugated (Cat. #AG-079) Melanotan-II Hormone NO-L-Tryptophan, Conjugated (Cat. #AG-075) Melatonin, Conjugated (Cat. #AG-038) NO-Lysine, Conjugated (Cat. #AG-073) Menopausal Gonadotropin, Human NO-Tyramine, Conjugated (Cat. #AG-080) Methionine Adenosyltransferase II Alpha Human Recombinant NO-Tyrosine, Conjugated (Cat. #AG-078) MHC class I chain-related gene A Human Recombinant NO2-Tyrosine, Conjugated (Cat. #AG-044) MHC class I chain-related gene B Human Recombinant Noggin Human Recombinant (Cat. #PRP-475) Microphtalmia Human Recombinant Noggin Mouse Recombinant Midkine Human Recombinant Non-Muscle Myosin-II Regulatory Light Chain Human Recombinant Page 54 Proteins, Peptides & Antigens (continued) Noradrenaline, Conjugated (Cat. #AG-006) PIN2-Interacting Protein 1 Human Recombinant Nucleobindin-2 Mouse Recombinant PKM2 Human Recombinant O-6-Methylguanine-DNA Methyltransferase Human Recombinant PL-12 Human Recombinant Octopamine, Conjugated (Cat. #AG-007) Placenta Growth Factor-1 Human Recombinant Octreotide Hormone Placenta Growth Factor-2 Human Recombinant Omentin Human Recombinant Placental Alkaline Phosphatase Human Recombinant Omentin Human Recombinant, His tag Plasminogen Activator Inhibitor-1 Oncostatin-M (209 a.a.) Human Recombinant Plasminogen Activator Inhibitor-1 Human Recombinant Oncostatin-M Human Recombinant Platelet Derived Growth Factor-A Human Recombinant Ornithine, Conjugated (Cat. #AG-061) Platelet Derived Growth Factor-AA Human Recombinant Osteoclast Stimulating Factor-1 Human Recombinant Platelet Derived Growth Factor-AA Human Recombinant, Yeast Osteocrin Human Recombinant Platelet Derived Growth Factor-AA Mouse Recombinant Osteopontin Human Recombinant Platelet Derived Growth Factor-AB Human Recombinant Osteoprotegerin Hi-5 Human Recombinant Platelet Derived Growth Factor-B Human Recombinant Osteoprotegerin Human Recombinant Platelet Derived Growth Factor-BB Human Recombinant Osteoprotegerin Human Recombinant, His tag Platelet Derived Growth Factor-BB Human Recombinant, Yeast Otoraplin Human Recombinant Platelet Derived Growth Factor-BB Mouse Recombinant Outer Membrane Protein-A Bacterial Recombinant Platelet Factor-4 Oxyntomodulin Human Recombinant Platelet Factor-4 (CXCL4) Human Recombinant Oxytocin Hormone Platelet Factor-4 (CXCL4) Mouse Recombinant P-Selectin Human Recombinant Platelet Factor-4 (CXCL4) Variant-1 Human Recombinant p21 Activated Kinase 4 Human Recombinant Pleiotrophin Human Recombinant p21-WAF1 Human Recombinant PM/Scl 100 Human Recombinant p38 alpha/SAPK2 alpha Human Recombinant Podoplanin Human Recombinant p504/alpha Methylacyl CoA Racemase Human Recombinant Polyphospate Kinase Recombinant p53 Human Recombinant Porcine Thrombin p53 Human Recombinant, Mutant PPARG (1-477) Human Recombinant p63 Human Recombinant PPARG Human Recombinant Pancreas S Duodenum Homeobox-1 Human Recombinant Pramlintide Hormone Pancreatitis-Associated Protein-1 Human Recombinant Pregnant Mare Serum Gonadotropin Parainfluenza Virus Type-1 Prelamin-A Recombinant Parainfluenza Virus Type-2 Pro Bone Morphogenetic protein-2 Human Recombinant Parainfluenza Virus Type-3 Pro-Nerve Growth Factor Human Recombinant Paraoxonase-1 Human Recombinant Procalcitonin Human Recombinant Paraoxonase-2 Human Recombinant Procalcitonin Human Recombinant, His tag Parathyroid Hormone Procathepsin K Human Recombinant Parathyroid Hormone (1-34) Human Recombinant Programmed Cell Death 4 Human Recombinant Parathyroid Hormone (1-84) Human Recombinant Programmed Cell Death 5 Human Recombinant Parathyroid Hormone (7-34) Human Recombinant Progranulin Human Recombinant Parvalbumin Rat Recombinant Proguanylin Human Recombinant Pentraxin-3 Human Recombinant Prolactin Human Recombinant Peptidyl-Prolyl Cis/Trans Isomerase Human Recombinant Prolactin Human Recombinant, His tag Peptidylprolyl Isomerase (Cyclophilin)-Like 1 Human Recombinant Prolactin Mouse Recombinant Periostin Human Recombinant Prolactin Ovine Recombinant Peripheral Myelin Protein-2 Human Recombinant Prolactin Ovine Recombinant, Antagonist Peripheral Myelin Protein-2 Human Recombinant, His tag Prolactin Rabbit Recombinant Peripherin Human Recombinant Prolactin Rat Recombinant Peroxiredoxin-1 Human Recombinant Prolactin Receptor Bovine Recombinant, soluble Peroxiredoxin-2 Human Recombinant Prolactin Receptor Human Recombinant Peroxiredoxin-3 Human Recombinant Prolactin Receptor Human Recombinant, GST Tag PEX Human Recombinant Prolactin Receptor Ovine Recombinant, soluble Pfu DNA Polymerase Recombinant Prolactin Receptor Rabbit Recombinant, soluble PGR Human Recombinant Prolactin Receptor Rainbow Trout Recombinant, soluble Phenyl Acetic Acid, Conjugated (Cat. #AG-010) Prolactin Receptor Rat Recombinant, soluble Phenylethylamine, Conjugated (Cat. #AG-098) Proliferating Cell Antigen Human Recombinant Phosphoethanolamine/Phosphocholine Phosphatase Human Recombinant Proliferating Cell Antigen Human Recombinant, S9 Phosphoinositide 3-kinase a, regulatory subunit Bovine Recombinant ProMatrix Metalloproteinase-7 Recombinant Phosphoinositide 3-kinase alpha p110a/p85a Bovine Recombinant Protease Recombinant Phosphoinositide 3-kinase beta P110 /p85a Human Recombinant Proteasome Subunit Alpha Type 7 Human Recombinant Phosphoinositide 3-kinase p110d/p85a Human Recombinant Proteasome Subunit Beta Type 1 Human Recombinant Phosphoinositide 3-kinase p110g Human Recombinant Protein A/G Recombinant Phosphoinositide 3-kinase p110g inactive mutant Human Recombinant Protein Arginine Methyltransferase 1 Human Recombinant Phosphoinositide 3-kinase p110gHis/p101GST Human Recombinant Protein Arginine Methyltransferase 1 Mouse Recombinant Phospholipase A2 P00630 Bee Venom Protein Recombinant Protein Disulfide Isomerase Human Recombinant Phosphoserine Phosphatase Human Recombinant Protein Export Protein SecB Recombinant Phytanic acid, Conjugated (Cat. #AG-122) Protein G 32 kDa Recombinant Picolinic Acid, Conjugated (Cat. #AG-120) Protein G Recombinant Pigment Epithelium-Derived Factor Human Recombinant Protein Kinase A catalytic subunit alpha c-AMP dependent Recombinant Pigment Epithelium-Derived Factor Human Recombinant, HEK Protein Kinase A Inactive holoenzyme type 1 alpha Recombinant Pigment Epithelium-Derived Factor Human Recombinant, His tag Protein Kinase A Inactive holoenzyme type 2 alpha Recombinant Page 55 Proteins, Peptides & Antigens (continued) Protein Kinase A regulatory subunit 2 alpha c-AMP dependent Recombinant S100A4 Human Recombinant Protein Kinase A regulatory subunit-1 alpha c-AMP dependent Recombinant S100A4 Human Recombinant, His tag Protein Kinase A regulatory subunit-1 alpha Recombinant S100A6 Protein Kinase Akt1/PKB alpha Active Enzyme Human Recombinant S100b Human Recombinant Protein Kinase Akt1/PKB alpha Inactive Enzyme Human Recombinant S100P Human Recombinant Protein Kinase C alpha Human Recombinant S100Z Human Recombinant Protein Kinase C beta 2 Human Recombinant Salmon Calcitonin Acetate Hormone Protein Kinase C beta I Human Recombinant (Cat. #PRP-318) SARS Envelope Recombinant Protein Kinase C delta Human Recombinant SARS Matrix Recombinant Protein Kinase C e Human Recombinant SARS Nucleocapsid (1-422) Recombinant Protein Kinase C gamma Human Recombinant SARS Nucleocapsid (1-49,192-220) Recombinant Protein Kinase C Inhibitor Protein-1 Human Recombinant SARS Nucleocapsid (1-49) Recombinant Protein Kinase C q Human Recombinant SARS Nucleocapsid (340-390) Recombinant Protein Kinase Casein Kinase 2 alpha Human Recombinant, His tag SARS S(C) Recombinant Protein Phosphatase 1, Regulatory Subunit-14A Human Recombinant SARS S(M) Recombinant Protein Phosphatase 1A alpha Human Recombinant SARS S(N) Recombinant Protein Phosphatase 1G Human Recombinant Schmidt-Ruppin A-2 Domain Mouse Recombinant Protein Phosphatase Inhibitor-1 Human Recombinant Secretagogin Human Recombinant Protein Tyrosine Phosphatase 1B Human Recombinant Secretagogin Rat Recombinant Prothrombin Complex Secreted Phospholipase A2-IB Human Recombinant Prouroguanylin Human Recombinant Secreted Phospholipase A2-IIA Human Recombinant PSP94 Human Recombinant Secreted Phospholipase A2-IID Human Recombinant PTEN Human Recombinant Secreted Phospholipase A2-IIE Human Recombinant Pyridoxal, Conjugated (Cat. #AG-102) Secreted Phospholipase A2-V Human Recombinant Pyridoxine, Conjugated (Cat. #AG-106) Secreted Phospholipase A2-X Human Recombinant Pyruvate Dehydrogenase Kinase Isozyme 1 Human Recombinant Secreted Phospholipase A2-XII Human Recombinant Quinaldinic Acid, Conjugated (Cat. #AG-119) Secreted Protein Acidic & Rich in Cysteine Human Recombinant Quinolinic Acid, Conjugated (Cat. #AG-033) Secretin Hormone RAB5A Human Recombinant (Cat. #PRP-590) Sepiapterin Reductase Human Recombinant Rabbit Skeletal Muscle Troponin-C Serpin Peptidase Inhibitor, Clade B Member 5 Human Recombinant RANK Ligand Human Recombinant, soluble SERT peptide (Cat. #PR-03) RANK Ligand Mouse Recombinant, soluble Sertuin-6 Human Recombinant RANK Ligand, GST Tag Human Recombinant, soluble Sf9 Cell Lysate (Cat. #PRT-258) Rantes (CCL5 Human Recombinant SHP-1 Human Recombinant Rantes Mouse Recombinant Sincalide Hormone Rantes Rat Recombinant SIV p55 Recombinant Ras Homolog Enriched in Brain Human Recombinant SLC4A4 Human Recombinant Ras-Related C3 Botulinum Toxin substrate 1 Human Recombinant SMAC/DIABLO Human Recombinant Ras-Related C3 Botulinum Toxin Substrate 2 Human Recombinant SMAD2 Human Recombinant Receptor Associated Protein Rat Recombinant SMAD4 Human Recombinant Recoverin Human Recombinant Small Ubiquitin-Related Modifier 1 Human Recombinant Regenerating Protein 1 alpha Human Recombinant Small Ubiquitin-Related Modifier 2 Human Recombinant Regenerating Protein 1 beta Human Recombinant Small Ubiquitin-Related Modifier 2 Human Recombinant, GST Regenerating Protein IV Human Recombinant SNAP Associated Protein Human Recombinant RELM-alpha Mouse Recombinant SNAP25 Human Recombinant (Cat. #PRP-573) RELM-alpha Mouse Recombinant, His tag SNAP25, C.elegans Recombinant RELM-beta Human Recombinant SNAP25B Human Recombinant RELM-Gamma Mouse Recombinant Somatostatin Hormone Resistin Human Recombinant Somatostatin Receptor-1 (SSTr1) Peptide (Cat. #PR-04) Resistin Human Recombinant, His tag Somatostatin Receptor-2 (SSTr2) Peptide (Cat. #PR-05) Resistin Mouse Recombinant Somatostatin Receptor-3 (SSTr3) Peptide (Cat. #PR-06) Resistin Mutant Human Recombinant Somatostatin Receptor-4 (SSTr4) Peptide (Cat. #PR-07) Resistin Rat Recombinant Somatostatin Receptor-5 (SSTr5) Peptide (Cat. #PR-08) Retinoblastoma Associated Protein Human Recombinant Sonic HedgeHog Mouse Recombinant Retinoic Acid, Conjugated (Cat. #AG-065) Soy Bean P34 Protein Recombinant Retinoid X Receptor Alpha Human Recombinant Soy Bean P34 Protein Recombinant, His tag Retinol Binding Protein-4 Human Recombinant (Cat. #PRP-535) Spastic Paraplegia 21 Human Recombinant Retinol Binding Protein-4 Human Recombinant, His tag (Cat. #PRP-536) Spectrin-alpha Recombinant Retnoid Acid Receptor Alpha Recombinant Spermine, Conjugated (Cat. #AG-062) Riboflavin, Conjugated (Cat. #AG-096) sRAGE Human Recombinant Ribosomal Phosphoprotein P0 Human Recombinant sRAGE, HEK Human Recombinant RO-52/SS-A Human Recombinant Stanniocalcin-1 Human Recombinant RO-60/SS-A Human Recombinant Stanniocalcin-2 Human Recombinant Rotenone, Conjugated (Cat. #AG-105) Staphylococcal Protein A 434aa Recombinant Rubella Virus Capsid C Recombinant Staphylococcal Protein-A Recombinant Rubella Virus E1 Mosaic Recombinant Staphylokinase Recombinant Rubella Virus E2 Recombinant STAT1 Human Recombinant S100A1 Human Recombinant STAT3 Human Recombinant S100A10 Human Recombinant Stathmin-1 Human Recombinant S100A11 Human Recombinant Stefin A Human Recombinant Page 56 Proteins, Peptides & Antigens (continued) Stem Cell Factor Human Recombinant Toxoplasma Gondii P30 (SAG 1) Recombinant Stem Cell Factor Mouse Recombinant Toxoplasma Gondii ROP4 RH2 Recombinant Stem Cell Factor Rat Recombinant TRAF Family Member-Associated NFKB Activator Human Recombinant Stem Cell Factor, Sf9 Human Recombinant Trans-4-Hydroxyproline, Conjugated (Cat. #AG-086) Streptavidin Transcription Elongation Factor B Polypeptide 2 Human Recombinant Streptavidin Recombinant, His tag Transcription Factor Binding to ighm Enhancer 3 Human Recombinant Streptavidin-NC Recombinant Transcription Termination/Antitermination L Factor E.Coli Recombinant Streptokinase Recombinant Transforming Growth Factor Beta Induced (182aa) Human Recombinant Stromal Cell-Derived Factor-1 alpha (CXCL12) Human Recombinant Transforming Growth Factor Beta Induced protein Human Recombinant Stromal Cell-Derived Factor-1 alpha (CXCL12) Human Recombinant, His tag Transforming Growth Factor Beta Receptor II Human Recombinant Stromal Cell-Derived Factor-1 alpha (CXCL12) Rat Recombinant Transforming Growth Factor-Beta 1 Stromal Cell-Derived Factor-1 alpha Mouse Recombinant Transforming Growth Factor-Beta 1 Human Recombinant Stromal Cell-Derived Factor-1 beta (CXCL12) Feline Recombinant Transforming Growth Factor-Beta 3 (644-850) Human Recombinant Stromal Cell-Derived Factor-1 beta (CXCL12) Human Recombinant Transforming Growth Factor-Beta 3 Human Recombinant Stromal Cell-Derived Factor-1 beta (CXCL12) Human Recombinant, His tag Trefoil Factor-1 Human Recombinant Stromal Cell-Derived Factor-1 beta (CXCL12) Rat Recombinant Trefoil Factor-1 Human Recombinant, His tag Stromal Cell-Derived Factor-1 beta Mouse Recombinant Trefoil Factor-2 Human Recombinant Stromal Interaction Molecule 1 Human Recombinant Trefoil Factor-2 Human Recombinant, His tag STUB1 Human Recombinant Trefoil Factor-3 Human Recombinant Succinic Acid, Conjugated (Cat. #AG-041) Treponema pallidum p15 Recombinant Superoxide Dismutase Human Recombinant Treponema pallidum p15 Recombinant (partial) Survivin Human Recombinant Treponema pallidum p15 Recombinant, His tag (partial) Synaptosomal-associated protein 25kDa Human Recombinant Treponema pallidum p17 Recombinant Syndecan-4 Human Recombinant (Cat. #PRP-583) Treponema pallidum p17 Recombinant (partial) Syntaxin-1A Human Recombinant Treponema pallidum p41 Mosaic Recombinant T4 DNA Ligase Recombinant Treponema pallidum p41 Recombinant Taq DNA Polymerase Recombinant Treponema pallidum p47 Recombinant Taq Plus DNA Polymerase Recombinant Treponema pallidum p47 Recombinant (partial) Taurine, Conjugated (Cat. #AG-042) Treponema pallidum TmpA Recombinant Terlipressin Hormone Treponema pallidum TmpA Recombinant (partial) Thiamine, Conjugated (Cat. #AG-095) Triptorelin Hormone Thioctic Acid, Conjugated (Cat. #AG-104) Tropic 1808 Rat Recombinant Thiopurine S-methyltransferase Human Recombinant Troponin 1 Human Recombinant Thioredoxin Human Recombinant Troponin I-C 2nd generation Recombinant, Single Chain Cardiac Thioredoxin Recombinant Troponin I-C Complex Human Recombinant Thioredoxin-2 Human Recombinant Troponin I-C Recombinant, Single Chain Cardiac Thioreduxin Reductase Yeast Recombinant Troponin T Type 2, Cardiac Isoform 3 Human Recombinant Threonyl t-RNA Synthetase Human Recombinant Troponin-C Human Recombinant Thrombin Troponin-I Human Recombinant Thrombopoietin Human Recombinant Troponin-T, Cardiac Thrombopoietin Mouse Recombinant Trypsin Bovine Recombinant Thrombopoietin, CHO Human Recombinant Tryptamine, Conjugated (Cat. #AG-018) Thrombospondin Human Recombinant Tubulin Folding Cofactor A Human Recombinant Thymic Stromal Lymphopoietin Human Recombinant Tumor Necrosis Factor Receptor Fusion Protein Human Recombinant Thymopentin Hormone Tumor Necrosis Factor-alpha Human Recombinant Thymosin-a1 Hormone Tumor Necrosis Factor-alpha Human Recombinant, His tag Thymosin-b4 Hormone Tumor Necrosis Factor-alpha Human Recombinant, Mutant Thymus and Activation Regulated Chemokine (CCL17) Human Recombinant Tumor Necrosis Factor-alpha Mouse Recombinant Thyroglobulin Tumor Necrosis Factor-alpha Porcine Recombinant Thyroid Peroxidase Human Recombinant Tumor Necrosis Factor-alpha Rat Recombinant Thyroid Stimulating Hormone Tumor Necrosis Factor-beta Human Recombinant Thyroid Transcription Factor-1 Human Recombinant Tumor Necrosis Factor-beta Human Recombinant, His tag Thyrostimulin Alpha Human Recombinant Tumor Protein D52 L1 Human Recombinant Thyrostimulin Beta Human Recombinant Tyramine, Conjugated (Cat. #AG-008) Thyrotropin Releasing Hormone Tyrosine Kinase ErbB-2 Human Recombinant TIE-1 Fc Chimera Human Recombinant Tyrosine Kinase ErbB-3 Human Recombinant TIE-1 Fc Chimera Mouse Recombinant U1-snRNP 68kDa Human Recombinant TIE-2 Fc Chimera Human Recombinant Ubiquitin Carboxyl-Terminal Hydrolase L1 GST tag Human Recombinant TIE-2 Fc Chimera Mouse Recombinant Ubiquitin Carboxyl-Terminal Hydrolase L1 Human Recombinant Tissue Plasminogen Activator Human Recombinant Ubiquitin Conjugating Enzyme 10 Human Recombinant Tissue Transglutaminase Human Recombinant Ubiquitin Conjugating Enzyme 12 Human Recombinant Tissue Transglutaminase Human Recombinant, Sf9 Ubiquitin Conjugating Enzyme 3 Human Recombinant TNF-Related Apoptosis Inducing Ligand/Apo2L (114-281) Human Recombinant Ubiquitin Conjugating Enzyme 7 Human Recombinant TNF-Related Apoptosis Inducing Ligand/Apo2L Human Recombinant Ubiquitin Conjugating Enzyme 7 Human Recombinant, His tag Tobacco Etch Virus Protease Recombinant Ubiquitin Conjugating Enzyme 9 Human Recombinant Topo-I Human DNA Recombinant Ubiquitin Conjugating Enzyme 9 Human Recombinant, His tag Topo-II Beta Human Recombinant (Cat. #PRP-303) Ubiquitin Conjugating Enzyme E2B Human Recombinant Toxoplasma Gondii MIC3 Recombinant Ubiquitin Conjugating Enzyme E2D3 Human Recombinant Toxoplasma Gondii P24 (GRA 1) Recombinant Ubiquitin Gly76 to Ala76 mutation Human Recombinant Toxoplasma Gondii P29 (GRA 7) Recombinant Ubiquitin Human Recombinant Page 57 Proteins, Peptides & Antigens (continued) Ubiquitin Human Recombinant, Biotin YWHA Human Recombinant, Beta Ubiquitin Lys 48 to Arg 48 mutation Human Recombinant YWHA Human Recombinant, Epsilon Ubiquitin-Conjugating Enzyme E2K Human Recombinant YWHA Human Recombinant, Gamma His tag Uracil DNA Glycosilase YWHA Human Recombinant, Tau Urate Oxidase Recombinant YWHA Human Recombinant, Zeta Urease Recombinant Zea Mays Casein Kinase 2 alpha Recombinant Uric Acid, Conjugated (Cat. #AG-115) Zeta Chain Associated Protein kinase 70 Human Recombinant Uridine phosphorylase Salmonella typhimurium Recombinant Zinc-Alpha 2 Glycoprotein Human Recombinant Urinary Trypsin Inhibitor (UTI) Zona Occludens 1 Human Recombinant Urinary Trypsin Inhibitor (UTI) Human Recombinant µ-Calpain Urokinase Urokplakin-3 Human Recombinant Uromodulin, Human Usher Syndrome 1C Human Recombinant Valeric Acid, Conjugated (Cat. #AG-112) Valproic Acid, Conjugated (Cat. #AG-117) VAMP1 Human Recombinant Protein VAMP2 Human Recombinant Protein (Cat. #PRP-578) VAMP3 Human Recombinant Protein VAMP5 Human Recombinant Protein VAMP8 Human Recombinant Protein Vascular Cell Adhesion Molecule 1 Human Recombinant Vasopressin Vaspin Human Recombinant VEGF B Human Recombinant VEGF C Human Recombinant VEGF C Rat Recombinant VEGF C Rat Recombinant (152) VEGF Human Recombinant VEGF Human Recombinant (121) VEGF Human Recombinant (121), His tag VEGF Human Recombinant (121), Sf9 VEGF Human Recombinant, CHO VEGF Human Recombinant, Endocrine Gland VEGF Human Recombinant, His tag VEGF Human Recombinant, Sf9 VEGF Human Recombinant, Yeast VEGF Mouse Recombinant VEGF Mouse Recombinant (121) VEGF Mouse Recombinant, Sf9 VEGF Rat Recombinant VEGF receptor-1 D1-3 Human Recombinant VEGF receptor-1 D1-3 Human Recombinant, His tag VEGF receptor-1 D1-4 Human Recombinant VEGF receptor-1 D1-5 Human Recombinant VEGF receptor-1 D1-7 Human Recombinant VEGF receptor-1 Human Recombinant VEGF receptor-2 Human Recombinant VEGF receptor-2 Human Recombinant, Fc Chimera VEGF receptor-3 Fc Chimera Human Recombinant VEGF receptor-3 Human Recombinant VEGF-E (Orf Virus) Recombinant VEGI Human Recombinant Ventricular Myosin Light Chain LCII Human Recombinant Vimentin Human Recombinant Visfatin Human Recombinant Visfatin Human Recombinant, His tag Visfatin Mouse Recombinant Visinin-Like Protein-1 Human Recombinant Von Hippel-Lindau Protein Human Recombinant VZV gE Recombinant VZV ORF26 Recombinant VZV ORF9 Recombinant WNT Inhibitory Factor 1 Human Recombinant WNV Envelope Recombinant WNV Pre-M Recombinant WW Domain Containing Oxidoreductase Human Recombinant Yamaguchi Sarcoma Virus Oncogene Homolog 1 Human Recombinant Yeast Thioredoxin Recombinant YWHA Human Recombinant Page 58 Index 192-IgG-SAP: 6 G N GABA: 14 Nerve Growth Factor Receptor. See NGFr A galanin-1 receptor: 14 neuropeptide Y (NPY): 18 Acetylated LDL-SAP: 7 Galanin-SAP: 13 NGFr: 5, 6, 17 , 18, 39 alpha-D-Galactopyranoside: 15 Ganglioside GM1 receptor: 12 NK-1 receptor: 20, 37 Anti-CD103-SAP: 9 GAT: 14 NPY-SAP: 18 Anti-CD22-SAP: 7 GAT1-SAP: 14 Anti-CD25-SAP: 8 Goat IgG-SAP: 28 O Goat-ZAP: 22 Anti-DAT-SAP: 9 OX7-SAP: 19 Griffonia (Bandeiraea) simplicifolia : 15 Anti-DBH-SAP: 10 oxytocin: 19 GRP receptor: 11 Anti-M-ZAP: 21 Oxytocin-SAP: 19 Anti-SERT-SAP: 11 avidin: 26 h P Hug-M-ZAP: 23 p75: 5, 6, 17, 18 Hum-ZAP: 23 B peptide conjugate: 27 biotinylated: 26 Human IgG-SAP: 28 Biotinylation Service: 26 R Blank-SAP: 27 I Rab-ZAP: 24 Bombesin-SAP: 10 IB4-SAP: 15 Rabbit IgG-SAP: 30 IgG goat monoclonal: 22 Rat IgG-SAP: 30 IgG human monoclonal: 23 C Rat-ZAP: 25 CCK. See Cholecystokinin IgG mouse monoclonal: 24 CCK-SAP: 12 IgG rabbit polyclonal: 24 CD103: 9 IgG rat monoclonal: 25 S CD11b. See Mac-1 (CD11b) receptor IgM mouse monoclonal: 21, 23 Saporin, Saponaria officinalis : 5 CD22: 7 integrin, alpha-E. See CD103 serotonin re-uptake transporter: 11 CD25: 8 Interleukin-2. See CD25 Somatostatin Receptor: 38 Cholecystokinin: 12 ipRGCs: 17 SP-CTA: 20 Cholera toxin B: 12 SSP-SAP: 20 Choline Acetyltransferase (ChAT): 36 L Streptavidin-ZAP: 26 Substance P: 20 Corticotropin-Releasing Factor: 12 leptin: 15 CRF. See Corticotropin-Releasing Factor Leptin-SAP: 15 CRF-SAP: 12 lipoprotein: 7 T CTB. See Cholera toxin B Tac. See CD25 CTB-SAP: 12 Thy-1.1: 19 Custom Conjugates: 25 M Mab-ZAP: 24 Mac-1: 16 D mac-1 (CD11b) receptor: 16 Antibodies are listed in DAT. See dopamine transporter Mac-1-SAP: 16 alphabetical order beginning on Dermorphin-SAP: 13 ME20.4-SAP: 17 page 31. dopamine: 9 melanopsin: 17 dopamine beta-hydroxylase (DBH): 10 Melanopsin-SAP: 17 Proteins, Peptides & Antigens are dopamine transporter: 9 microglia: 7 listed in alphabetical order MOR. See mu-opioid receptor beginning on page 42. F MOR-SAP: 13 Fab-ZAP: 22 Mouse IgG-SAP: 29 FGF-SAP: 13 Mouse IgM-SAP: 29 fibroblast growth factor: 13 mu p75-SAP: 18 mu-opioid receptor: 13

Page 59 Authorized Distributors

You may place your order with our local distributor in the countries listed below. For orders in the United States and Europe, please contact ATS directly. Australia Korea Beijing 4A Biotech Co.Ltd. Biocore Pty Limited JYSCO Guanglian Industrial Park, 204 Henderson Road #302 Jeonglim Bd. Ciqu Zheng,Tongzhou, Alexandria 207 Poi-dong, Gangnam-gu Beijing, 101111 China Sydney NSW 2015 AUSTRALIA Seoul, Korea 8610-52116834 phone 612-9565-1281 phone 82 (0)2 571 3444 phone 400-7060-959 toll-free 612-9565-5965 fax 82 (0)2 571 4877 fax 8610-52116831 fax [email protected] email [email protected] email [email protected] email Brazil India Sungwoo Life Science Co, Ltd 560-5, Uijeongbu 2 Dong Sellex, Inc Biogenuix 5225 Wisconsin Avenue Uijeongbu City, Kyungki Do B-413, 4th Floor, Ansal Chamber I 480-849 Korea Suite 306 Bhikaji Cama Place Washington DC 20015 +82-2-985-7471 phone New Delhi-66, India 202-686-3044 phone +82-31-876-9149 fax 9+91-11-41658590 phone/fax [email protected] 202-686-3177 fax [email protected] email [email protected] email Singapore Canada Aquin Technologies Pvt Ltd No 8. -1st floor, Akashya Nagar i-DNA Biotechnology Pte Ltd Cedarlane Laboratories T.C. Palya Main Road 41 Science Park Road, #04-03A 4410 Paletta Court Bangalore -560016. India Gemini Burlington, ON L7L5R2 91-80 4344 3005 phone Singapore Science Park II CANADA [email protected] email SINGAPORE 117610 289-288-0001 phone +(65) 9622 1086 phone 289-288-0020 fax Japan +(65) 6776 0368 fax [email protected] email Funakoshi Co, Ltd [email protected] email China 9-7 Hongo 2-chome, Bunkyho-ku Tokyo 113-0033 JAPAN Switzerland Advanced Technol & Ind Co, Ltd 03-5684-1620 phone LuBioScience GmbH Unit B, 1/F, Cheong Shing Ind Bldg 03-5684-1775 fax Topferstrasse 5 17 Walnut St, Tai Kok Tsui, [email protected] email P.O. Box KLN, HONG KONG 6000 Lucerne 6 852 23902293/23945546 phone Switzerland 852 27898314 fax 0041 41 417 02 80 phone [email protected] email 0041 41 417 02 89 fax www.lubio.ch

10451 Roselle Street, #300 PO Box 4 San Diego, CA 92121 USA 6680 AA Bemmel (877) 889-2288 toll-free The Netherlands (European Sales Office) (858) 642-1988 tel • (858) 642-1989 fax +31(0)13-7504532 tel • +31(0)13-7504533 fax [email protected] email [email protected] email