Gastroenteritis Acute, Nonspecific
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Inflammatory Bowel Disease Irritable Bowel Syndrome
Inflammatory Bowel Disease and Irritable Bowel Syndrome Similarities and Differences 2 www.ccfa.org IBD Help Center: 888.MY.GUT.PAIN 888.694.8872 Important Differences Between IBD and IBS Many diseases and conditions can affect the gastrointestinal (GI) tract, which is part of the digestive system and includes the esophagus, stomach, small intestine and large intestine. These diseases and conditions include inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). IBD Help Center: 888.MY.GUT.PAIN 888.694.8872 www.ccfa.org 3 Inflammatory bowel diseases are a group of inflammatory conditions in which the body’s own immune system attacks parts of the digestive system. Inflammatory Bowel Disease Inflammatory bowel diseases are a group of inflamma- Causes tory conditions in which the body’s own immune system attacks parts of the digestive system. The two most com- The exact cause of IBD remains unknown. Researchers mon inflammatory bowel diseases are Crohn’s disease believe that a combination of four factors lead to IBD: a (CD) and ulcerative colitis (UC). IBD affects as many as 1.4 genetic component, an environmental trigger, an imbal- million Americans, most of whom are diagnosed before ance of intestinal bacteria and an inappropriate reaction age 35. There is no cure for IBD but there are treatments to from the immune system. Immune cells normally protect reduce and control the symptoms of the disease. the body from infection, but in people with IBD, the immune system mistakes harmless substances in the CD and UC cause chronic inflammation of the GI tract. CD intestine for foreign substances and launches an attack, can affect any part of the GI tract, but frequently affects the resulting in inflammation. -
Chronic Viral Hepatitis in a Cohort of Inflammatory Bowel Disease
pathogens Article Chronic Viral Hepatitis in a Cohort of Inflammatory Bowel Disease Patients from Southern Italy: A Case-Control Study Giuseppe Losurdo 1,2 , Andrea Iannone 1, Antonella Contaldo 1, Michele Barone 1 , Enzo Ierardi 1 , Alfredo Di Leo 1,* and Mariabeatrice Principi 1 1 Section of Gastroenterology, Department of Emergency and Organ Transplantation, University “Aldo Moro” of Bari, 70124 Bari, Italy; [email protected] (G.L.); [email protected] (A.I.); [email protected] (A.C.); [email protected] (M.B.); [email protected] (E.I.); [email protected] (M.P.) 2 Ph.D. Course in Organs and Tissues Transplantation and Cellular Therapies, Department of Emergency and Organ Transplantation, University “Aldo Moro” of Bari, 70124 Bari, Italy * Correspondence: [email protected]; Tel.: +39-080-559-2925 Received: 14 September 2020; Accepted: 21 October 2020; Published: 23 October 2020 Abstract: We performed an epidemiologic study to assess the prevalence of chronic viral hepatitis in inflammatory bowel disease (IBD) and to detect their possible relationships. Methods: It was a single centre cohort cross-sectional study, during October 2016 and October 2017. Consecutive IBD adult patients and a control group of non-IBD subjects were recruited. All patients underwent laboratory investigations to detect chronic hepatitis B (HBV) and C (HCV) infection. Parameters of liver function, elastography and IBD features were collected. Univariate analysis was performed by Student’s t or chi-square test. Multivariate analysis was performed by binomial logistic regression and odds ratios (ORs) were calculated. We enrolled 807 IBD patients and 189 controls. Thirty-five (4.3%) had chronic viral hepatitis: 28 HCV (3.4%, versus 5.3% in controls, p = 0.24) and 7 HBV (0.9% versus 0.5% in controls, p = 0.64). -
Ulcerative Colitis: Diagnosis and Treatment ROBERT C
Ulcerative Colitis: Diagnosis and Treatment ROBERT C. LANGAN, MD; PATRICIA B. GOTSCH, MD; MICHAEL A. KRAFCZYK, MD; and DAVID D. SKILLINGE, DO, St. Luke’s Family Medicine Residency, Bethlehem, Pennsylvania Ulcerative colitis is a chronic disease with recurrent symptoms and significant morbidity. The precise etiology is still unknown. As many as 25 percent of patients with ulcerative colitis have extraintestinal manifestations. The diagnosis is made endoscopically. Tests such as perinuclear antineutrophilic cytoplasmic antibodies and anti-Saccharomyces cerevisiae antibodies are promising, but not yet recommended for routine use. Treatment is based on the extent and severity of the disease. Rectal therapy with 5-aminosalicylic acid compounds is used for proc- titis. More extensive disease requires treatment with oral 5-aminosalicylic acid compounds and oral corticosteroids. The side effects of steroids limit their usefulness for chronic therapy. Patients who do not respond to treatment with oral corticosteroids require hospitalization and intravenous steroids. Refractory symptoms may be treated with azathioprine or infliximab. Surgical treatment of ulcerative colitis is reserved for patients who fail medical therapy or who develop severe hemorrhage, perforation, or cancer. Longstanding ulcerative colitis is associated with an increased risk of colon cancer. Patients should receive an initial screening colonos- copy eight years after the onset of pancolitis and 12 to 15 years after the onset of left-sided dis- ease; follow-up colonoscopy should be repeated every two to three years. (Am Fam Physician 2007;76:1323-30, 1331. Copyright © 2007 American Academy of Family Physicians.) This article exempli- lcerative colitis is a chronic dis- of ulcerative colitis is not well understood. -
Liver Disease in Ulcerative Colitis: an Epidemiological and Follow up Study
84 Gut 1994; 35:84-89 Liver disease in ulcerative colitis: an epidemiological and follow up study in the county of Stockholm Gut: first published as 10.1136/gut.35.1.84 on 1 January 1994. Downloaded from U Broome, H Glaumann, G Hellers, B Nilsson, J Sorstad, R Hultcrantz Abstract sclerosing cholangitis (PSC) are said to be more In an epidemiological study ofthe incidence of common in patients with UC.47 The incidence of ulcerative colitis (UC) in the county of Stock- these complications varies in different studies holm between 1955 and 1979, 1274 patients depending on selection criteria and on the with UC were discovered. Almost all these definition of hepatobiliary disease.89 The true patients had regularly been investigated with incidence of hepatobiliary dysfunction in UC, liver function tests; 142 (11%) of them showed however, can only be obtained by tests of liver signs of hepatobiliary disease. A follow up function tests such as transaminases, alkaline study on all 142 patients with abnormal liver phosphatases, and bilirubin made routinely in function and UC was made between 1989 and unselected groups of patients with UC. Because 1991 to evaluate the cause of the liver abnor- the cause of hepatic involvement in UC is mality and to find out if the liver disease had enigmatic it is important to find out if the rate affected the survival rates. At follow up, eight of this complication is increasing, because of patients were reclassified as having Crohn's factors unrelated to UC, or if it mirrors the disease, 60 had developed normal liver func- incidence ofUC in itself. -
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FOR CATS FOR DOGS DIAGNOSIS AND MANAGEMENT OF GASTROINTESTINAL DISORDERS INTRO INTRODUCTION YOUR PARTNER Hill’s is here to support you to help your patients You can visit our professional website (www.hillsvet.co.uk or www.hillsvet.ie) for a wealth of useful information: PRODUCTS – Detailed product information, nutritional profiles, indications and contra-indications of Hill’s products. QUICK RECO – Do you want to make a written (or email) recommendation You can use this booklet as a concise reference to aid in the diagnosis and management for a particular patient? You can do so in just a few clicks. of gastrointestinal (GI) problems in cats and dogs, brought to you by Hill’s Pet Nutrition, your partner in education and nutritional excellence. ENQUIRIES – Our team of dietary consultants and Hill’s Veterinary Staff Clinicians are available to answer questions from veterinary staff and pet owners: CONTENTS INCLUDE: • Hill’s Customer Services Department 0800 282 438 / 1–800 626 002 (ROI) A broad overview of the normal anatomy and function of the GI tract. • Technical enquiries 01483464641 The signalment, symptoms and clinical signs, diagnostic tests, treatment and nutritional management of commonly encountered GI disorders. HILL’S VETERINARY NUTRITION ACADEMY is a unique online educational GENERAL POINTS: experience and is available at no cost to every member of the veterinary health care team. This booklet does not attempt to cover all GI diseases and is not a full diagnostic and management overview.* For more detailed information, please refer to veterinary text books.1 GI symptoms are concerning for caring owners and are a common reason for seeking a HILL’S DIGESTIVE INDEX APP - Score the severity of the signs of chronic veterinary consultation. -
Peptic Ulceration in Crohn's Disease (Regional Gut: First Published As 10.1136/Gut.11.12.998 on 1 December 1970
Gut, 1970, 11, 998-1000 Peptic ulceration in Crohn's disease (regional Gut: first published as 10.1136/gut.11.12.998 on 1 December 1970. Downloaded from enteritis) J. F. FIELDING AND W. T. COOKE From the Nutritional and Intestinal Unit, The General Hospital, Birmingham 4 SUMMARY The incidence of peptic ulceration in a personal series of 300 patients with Crohn's disease was 8%. Resection of 60 or more centimetres of the small intestine was associated with significantly increased acid output, both basally and following pentagastrin stimulation. Only five (4 %) of the 124 patients who received steroid therapy developed peptic ulceration. It is suggested that resection of the distal small bowel may be a factor in the probable increase of peptic ulceration in Crohn's disease. Peptic ulceration was observed in 4% of 600 1944 and 1969 for a mean period of 11-7 years patients with Crohn's disease by van Patter, with a mean duration of the disorder of 13.7 Bargen, Dockerty, Feldman, Mayo, and Waugh years. Fifty-one of these patients had Crohn's http://gut.bmj.com/ in 1954. Cooke (1955) stated that 11 of 90 patients colitis. Diagnosis in this series was based on with Crohn's disease had radiological evidence of macroscopic or histological criteria in 273 peptic ulceration whilst Chapin, Scudamore, patients, on clinical and radiological data in 25 Bagenstoss, and Bargen (1956) noted duodenal patients, and on clinical data together with minor ulceration in five of 39 (12.8%) successive radiological features in two patients with colonic patients with the disease who came to necropsy. -
Diabetes Mellitus (Part One)
JOURNAL OF CHINESE MEDICINE NUMBER 58 SEPTEMBER 1998 MODERN MEDICINE AND TRADITIONAL CHINESE MEDICINE DIABETES MELLITUS (PART ONE) by Clinton J. Choate 1. Background the conventional medical approach of simply using insulin There is nothing new about diabetes; it has been a medical or oral drugs to treat diabetes is incomplete and the person problem since antiquity. The name which was originated relying on them to prevent long-term complications re- by Aretaeus (30-90 CE) came from the Greek words mean- mains at risk. ing ‘siphon’ and ‘to run through’, signifying the chronic excretion of an excessive volume of urine. About Blood Sugar Diabetes mellitus, because of its frequency, is probably Carbohydrate is the active fuel of the body and is ordinarily the single most important metabolic disease and is widely the main source of energy of the tissue cell. In the normal recognized as one of the leading causes of death and disabil- digestive process, food sugars and starches (carbohydrates) ity in the United States. It affects every cell in the body and are changed into sugar glucose. This is stored in the form of the essential biochemical processes that go on there. glycogen (animal starch) in the liver and muscles for later Diabetes has been linked to the western lifestyle, as it is use as a body fuel, at which time it is reconverted into uncommon in cultures consuming a more primitive diet. glucose. Blood sugar rises somewhat after eating, and in As cultures switch from their native diets to more commercial healthy individuals returns to normal levels in about an foods, their rate of diabetes increases, eventually reaching hour or two. -
Crohn's Disease and Ulcerative Colitis in the Same Patient
Gut: first published as 10.1136/gut.24.9.857 on 1 September 1983. Downloaded from Gut, 1983, 24, 857-862 Case report Crohn's disease and ulcerative colitis in the same patient C L WHITE III, S R HAMILTON, M P DIAMOND, AND J L CAMERON From the Departments ofPathology, Medicine, and Surgery, The Johns Hopkins University School of Medicine and Hospital, Baltimore, Maryland, USA SUMMARY A well documented case of a patient with both Crohn's disease and ulcerative colitis is presented. A 29 year old woman underwent resection of her terminal ileum and ascending colon for typical Crohn's disease with ileocolitis. Eleven years later, an ileoproctocolectomy was performed for typical ulcerative colitis involving the left colon. The resection specimen also showed evidence of colonic Crohn's disease near the anastomotic site. This unusual case shows that Crohn's disease and ulcerative colitis can occur in the same patient. The rarity of such cases supports the concept that Crohn's disease and ulcerative colitis are separate entities, rather than different manifestations of the same disease process. Crohn's disease and ulcerative colitis are the two healed with conservative measures. Four months well recognised forms of idiopathic inflammatory later she developed rectal bleeding. Proctoscopy bowel disease. As the aetiologies (or aetiology) of showed slightly inflamed rectal mucosa, but no idiopathic inflammatory bowel disease are biopsy was performed. Barium enema showed a unknown, these entities are distinguished on the stricture in the ascending colon; the caecum and basis of their pathologic and resulting clinical, and colon distal to the hepatic flexure were normal. -
Nutrition Strategies for Managing Diabetes in Healthcare 2.0
Nutrition Strategies for Managing Diabetes in Healthcare 2.0 1 Overview Part 1 The 4 Goals of the American Diabetes Association’s Nutrition Therapy Recommendations Part 2 Stages of Change Motivational Interviewing AADE7 Self-Care Behaviors™ 2 Part 1 3 Review ………… ………… Outline 4 Types of Diabetes 4 ADA Nutrition 1. Pre-diabetes Recommendations 2. Gestational Diabetes 1. Eating patterns 3. Type 1 diabetes 2. Enjoy food 4. Type 2 diabetes 3. Individual needs 4. Tools and resources Carbohydrate Counting 1. What are carbohydrate foods? 2. How much is one choice? 3. How many choices to have at each meal and snack? 4 ADA Nutrition Recommendations: Goal 1 A. Promote and support healthful eating patterns, emphasizing a variety of nutrient-dense foods in appropriate portion sizes specifically to: Attain individualized glycemic, blood pressure, and lipid goals Achieve and maintain body weight goals Delay or prevent complications of diabetes Diabetes Diagnosis Lipid Healthy Glucose Hypertension Complications Disorders Lifestyle ADA Nutrition Recommendations, Diabetes Care (2013) ADA Standards of Care, Diabetes Care (2016) 5 Medical Nutrition Therapy (MNT): Impact on A1c Hemoglobin A1c is a blood measurement that reflects the level of glucose in the blood over the past 2-3 months MNT is effective in lowering A1c Type 1: 0.3 - 1% Type 2: 0.5 - 2 % Evidence The amount of carbohydrates and available insulin may be the most important factor influencing glycemic response after eating (A) Monitoring carbohydrate intake, whether by carbohydrate -
Obesity: When to Consider Medication
Obesity: When to consider medication These 4 cases illustrate how weight loss drugs—including the 4 newest— can be integrated into a treatment plan that includes diet, exercise, and behavior modification Katherine H. Saunders, MD; Alpana P. Shukla, MD, MRCP; Leon I. Igel, MD; and Louis J. Aronne, MD odest weight loss of 5% to 10% Until recently, there were few pharma- among patients who are overweight cologic options approved by the US Food M or obese can result in a clinically and Drug Administration (FDA) for the relevant reduction in cardiovascular (CV) management of obesity. The mainstays of disease risk.1 This amount of weight loss can treatment were phentermine (Adipex-P, Ion- increase insulin sensitivity in adipose tissue, amin, Suprenza) and orlistat (Alli, Xenical). liver, and muscle, and have a positive impact Since 2012, however, 4 agents have been on blood sugar, blood pressure, triglycerides, approved as adjuncts to a reduced-calorie 1,2 and high-density lipoprotein cholesterol. diet and increased physical activity for long- IN THIS All patients who are obese or overweight term weight management.8,9 Phentermine/ ARTICLE with increased CV risk should be counseled topiramate extended-release (ER) (Qsymia) on diet, exercise, and other behavioral inter- and lorcaserin (Belviq) were approved Antiobesity 3 10,11 ventions. Weight loss secondary to lifestyle in 2012, and naltrexone sustained re- medication details modification alone, however, leads to adap- lease (SR)/bupropion SR (Contrave) and page 42 tive physiologic responses, which increase liraglutide 3 mg (Saxenda) were approved appetite and reduce energy expenditure.4–6 in 201412,13 (TABLE9,14–39). -
Acute Gastroenteritis: Adult ______Gastrointestinal
Acute Gastroenteritis: Adult _____________________________ Gastrointestinal Clinical Decision Tool for RNs with Effective Date: December 1, 2019 Authorized Practice [RN(AAP)s] Review Date: December 1, 2022 Background Gastroenteritis, also known as enteritis or gastroenterocolitis, is an inflammation of the stomach and intestines that manifests as anorexia, nausea, vomiting, and diarrhea (Thomas, 2019). Gastroenteritis can be acute or chronic and can be caused by bacteria, viruses, parasites, injury to the bowel mucosa, inorganic poisons (sodium nitrate), organic poisons (mushrooms, shellfish), and drugs (Thomas, 2019). Chronic causes include food allergies and intolerances, stress, and lactase deficiency (Thomas, 2019). Gastroenteritis caused by bacterial toxins in food is often known as food poisoning and should be suspected when groups of individuals present with the same symptoms (Thomas, 2019). Immediate Consultation Requirements The RN(AAP) should seek immediate consultation from a physician/NP when any of the following circumstances exist: ● moderate dehydration (six to 10% loss of body weight), and blood pressure and mental status do not stabilize in the normal range within one hour of initiating rehydration therapy; ● severe dehydration (>10% loss of body weight); ● high fever and appears acutely ill; ● tachycardia or palpitations; ● hypotension; ● severe headache; ● blood or pus in stool; ● severe abdominal pain; ● abdominal distention; ● absent bowel sounds; ● altered mental status; ● older and immunocompromised clients; and/or ● severe vomiting (Interprofessional Advisory Group [IPAG], personal communication, October 20, 2019). GI | Acute Gastroenteritis - Adult The RN(AAP) should initiate an intravenous fluid replacement as ordered by the physician/NP or as contained in an applicable RN Clinical Protocol within RN Specialty Practices if any of the Immediate Consultation circumstances exist. -
Gastroenteritis in Dogs
Dog Diseases & Conditions A-Z - Page 1/2 Gastroenteritis in Dogs Overview A complete blood count to evaluate Gastroenteritis is an irritation of the stomach and inflammation, infection, anemia, and other intestines; it usually results in vomiting and diarrhea blood-related conditions . There are several causes of gastroenteritis: metabolic Electrolyte tests to ensure your dog is neither disorders, dietary indiscretion (this means ingesting dehydrated nor suffering from an electrolyte inappropriate things, like garbage or the feces of other imbalance animals), inflammatory bowel disease, parasites, X-rays of the abdomen to evaluate for foreign bacteria, viruses, or allergies can all cause vomiting and material and/or obstruction of the diarrhea. gastrointestinal tract Ultrasound imaging of your dog’s digestive tract One of the leading causes of gastroenteritis is feeding a and other major abdominal organs pet “people” food or table scraps. An obstruction in the An endoscopy to evaluate the lining of the digestive tract can also trigger gastroenteritis, so a stomach and intestinal tract missing sock or favorite holiday ornament could also be Specific tests to rule out viral infections, such as the culprit. parvovirus Fecal tests to identify if fecal parasites could be Risk and Signs the cause All dogs and puppies are at risk for gastroenteritis, Special fecal tests, such as cultures and which can cause extreme vomiting and diarrhea, polymerase chain reaction (PCR) testing leading to dehydration and an electrolyte imbalance. Contact your veterinarian immediately if the vomiting Dogs with gastroenteritis, regardless of the cause, are and diarrhea persist. often dehydrated and sometimes need to be given fluids under the skin (subcutaneously) or directly into a In addition to vomiting and diarrhea, your pet may vein (intravenously).