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ORAL SESSION 1 Retinal Degeneration I

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ORAL SESSION 1 Retinal Degeneration I Contents Welcome ..................................................................................................... 1 Committees ................................................................................................ 2 Programme 2013 ....................................................................................... 6 ISCEV Course 2013 ................................................................................... 7 Program Overview................................................................................... 11 Abstracts 2013 .........................................................................................19 General Information ................................................................................91 Introduction to Invited Speakers...........................................................98 Author Index...........................................................................................104 Acknowledgement................................................................................. 112 Welcome Welcome Dear Friends, I’d like to extend a warm welcome on behalf of Southwest Eye Hospital of Third Military Medical University for the 51st ISCEV Symposium. I am honored to have the opportunity to hold this symposium and have been waiting for the time when experts on the electrophysiology meet in Chongqing and share the new ideas and new technologies on visual electrophysiology. Chongqing is the largest and youngest municipality in China and once was the country’s capital. The region has more than 3000 years of culture and offers the best of modern and traditional culture. Key tourist attractions include UNESCO World Heritage sites such as the 9th century Dazu Rock Carvings, Three Gorges in the Yangtze River, Jiuzhai valley, and the ancient village of Ci Qi Kou (Porcelain Village). Also you can enjoy the beautiful scene of Mountain Jinyun and the famous hot spring there, Mountain Fairy and so on. Chongqing is famous for its tasty food, especially the hotpot which you should not miss. You will also be impressed by the passion of the Chongqing people. Many thanks to my colleagues and the ISCEV members who have supported me in my job as chair of the local organizing committee. I sincerely wish for this symposium to be a great success and that all of you can share and acquire more knowledge about electrophysiology and enjoy your stay in Chongqing. Professor Zheng Qin YIN Chair of local organizing committee of 51st Symposium of ISCEV Vice-President of Chinese Ophthalmology Society Chair of Chinese Visual Physiology and Visual Science committee in Chinese Ophthalmology Society Professor and Director of Southwest Eye Hospital, Third Military Medical University, Chongqing, China Professor and Director of Dept. Ophthalmology, Chinese PLA General Hospital, Beijing, China Chair of the Key lab of Visual Damage and Regeneration & Restoration in Chongqing 1 Committees st Committee of 51 ISCEV symposia Program Committee A Patrizia Tormene MD Ruth Hamilton PhD Shuichi Yamamoto MD,PhD Zheng Qin Yin MD,PhD Bo Lei MD,PhD Local Organizing Committee Zheng Qin Yin MD,PhD Bo Lei MD,PhD Tao Yu MD,PhD Shi Ying Li MD,PhD Su Jun Zhou Ying Chun Miao Fu Rong Zheng Hong Wang Yang Liu Min Wang Jia Man Dai 2 Committees Chinese Visual Physiology and Visual Science committee Zheng Qi n Yin Zuo Mi ng Zhang Shi Zhou Huang Hou Bin Huang Shi Gang He Li Bin Jiang Chao Yin Wang Wei Jin Yin Bo Lei Wei Zhang Qin C hang Yan Teng Yi n S hen Qiong Zhang Lian Hong Pi Bai Hua C hen Jun Ping Yao Min Luo Rui Fang S ui Shi Ying Li 3 Committees Brief Introduction of International Society for Clinical Electrophysiology of Vision (ISCEV) President Secretary in General A PatriziaTormene, Ruth Hamilton Ophthalmic Clinic Padova Glasgow, UK University, Italy Vice President Vice President (Europe/Africa) (Asia/Australia) Richard Smith Shuichi Yamamoto Chairman of Revalidation Department of Subcommittee Ophthalmology and Visual Science, Chiba The Royal College of University Graduate Ophthalmologists, UK School of Medicine, Japan Vice President Director of (Americas) International Mitch Brigell Communications Michael Bach Director of Clinical Research, Ophthalmology Aerpio Ophthalmology, Therapeutics Cambridge, MA University of Freiburg, USA Germany 4 Committees Director of Director of Education Graham E Holder Standards Consultant Daphne L McCulloch Electrophysiologist Director of Optometrist and supervisor, Electrophysiology, GCU Infant Vision and Learning Moorfields Eye Hospital, Disability Vision Clinics, UK London,UK Treasurer Editor of Documenta Ophthalmologica Ulrich Kellner Laura Frishman Rare retinal disease center, Moores Professor, AugenZentrum Siegburg; Assoc. Dean Retina Science, Postfach, College of Optometry, Bonn, Germany University of Houston, Houston, USA Member-at-large Member-at-large Dorothy Thompson Carol Westall Great Ormond Street Hospital Professor of Ophthalmology for Children, UCL ICH London, and Vision Sciences UK University of Toronto and Hospital for Sick Children, Canada Member-at-large Member-at-large Mineo Kondo Mathias Seeliger Department of Division of Ocular Ophthalmology, Mie University Neurodegeneration, Institute for Graduate School of Medicine, Ophthalmic Research, Centre for Japan Ophthalmology,Tuebingen, Germany 5 Committees Member-at-large Member-at-large Marko Hawlina Zheng Qin Yin Ophthalmology at Medical Southwest Hospital/Southwest Faculty of University of Eye Hospital, Third Military Ljubljana, Slovenia Medical University Chongqing, China 6 Committees PROGRAM Wednesday Thursday Saturday 12th Sunday 13th Monday 14th Tuesday 15th 16th 17th 7:30 Documenta 8:00 Opening editorial board Cerem ony meeting 8:30 Invited W. Dawson Bus tour Lectures Memorial departs 9:00 Prof.Wu LZ, Lecture, Prof. OS 8 retinal Prof.Yin ZQ Yang XL degeneration II 9:30 OS 1 Retinal OS 5 Optic degeneration I nerve 10:00 Courses Poster session Courses (human & Arrive Dazu C (human & animal) 10:30 animal) coffee & coffee & Rock (coffee & Carvings, exhibition exhibition exhibition) Baoding 11:00 Grottoes OS 2 Origins of OS 9 OS 6 Animal (World 11:30 electrophysiolog Vessels and s tudies Heritage ical signals toxicology Site) 12:00 12:30 Packed Lunch & Lunch & Lunch& Lunch Lunch lunches 13:00 exhibition exhibition exhibition (½ hr bus 13:30 trip) OS 3 OS 7 14:00 Development Electrophysiology Membership & paediatrics throughout the Meeting 14:30 visual pathway Courses Courses Board Long Shui (human & (human & 15:00 meeting Lake for animal) animal) Poster session A Awards ISCEV (coffee & Poster session B 15:30 Olym pics Emiko Adachi exhibition) (coffee & lecture exhibition) 16:00 Prof.Tazawa Y lecture 16:30 OS 4 Techniques 17:00 Clinical cases Dinner at Cruise & local 17:30 farewell dinner restaurant 18:00 Buses Standards depart 18:30 Hotpot for session course Welcome Photograph 19:00 delegates (and Reception early (smart casual) Banquet with 19:30 s ym pos ium Dinner at a performance arrivers) local (form al dress) Arrive 20:00 restaurant Chongqing 20:30 7 ISCEV Courses ISCEV Courses 2013 12th-13th October Human Course Day 1 08.00-08.30 Registration and coffee 08.30-09.05 Welcome, test overview and introduction to the ERG. Graham Holder will overview the tests and describe the basics of ERG recording and generation 09.05-10.00 Clinical ERG. Ulrich Kellner will describe how the ERG can localise retinal dysfunction to cell types and layers 10.00-10.20 Lecture: The (electro-)negative ERG. Graham Holder will describe the clinical implications of this finding 10.20-10.30 Discussion 10.30-11.00 Coffee break 11.00-11.20 Lecture: mfERG basics. Michael Bach 11.20-11.45 Lecture: Clinical mfERG. Charlotte Poloschek 11.45-12.10 Lecture: Introduction to the PERG. Michael Bach will present the origin and recording of the PERG 12.10-12.35 Lecture: Clinical applications of the PERG Graham Holder 12.35-12.40 Discussion 12.40-13.40 Lunch 13.40-14.10 Lecture: Specialized ERG techniques: ON- / OFF- and S-cone ERGs. Chris Hogg will describe the recording and clinical applications of these responses 14.10-14.30 Lecture: Recording and clinical applications of the EOG. Graham Holder 8 ISCEV Courses 14.30-15.15 Lecture: Technical aspects Chris Hogg will present topics related to technical aspects of recording: amplifier and filter characteristics, sources and remedies of artefacts etc. 15.15-15.45 Lecture: A diagnostic approach to retinal dystrophies. Ulrich Kellner will discuss diagnostic issues. 15.45-end Practical demonstration: The faculty will use commercial electrophysiology systems to demonstrate visual electrophysiology techniques. Coffee will be available throughout 19.00 Evening event: dinner Day 2 08.30-09.00 Lecture: Introduction to the VEP. Michael Bach will present the origin and recording of the VEP 09.00-09.40 Lecture: Clinical VEP. Graham Holder will discuss the clinical applications of the VEP 09.40--10.30 Lecture: Paediatric techniques. Dorothy Thompson will discuss the uses of electrophysiology in a paediatric setting 10.30-10.40 Discussion 10.40-11.15 Coffee break 11.15-12.15 Lecture: Clinical correlations and making the diagnosis. Graham Holder will discuss the role of the tests in diagnosis, including the integration of information from several tests as appropriate 12.15-12.30 Discussion 12.30-13.30 Lunch 13.30-end Workshops: Opportunity to undertake hands-on recordings on volunteers, with guidance by members of the faculty and equipment manufacturers. 9 ISCEV Courses Animal Course Program Date Time Course Program Chairs
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