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Deutsches Institut Für Ernährungsforschung Potsdam-Rehbrücke German Institute of Human Nutrition

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Deutsches Institut Für Ernährungsforschung Potsdam-Rehbrücke German Institute of Human Nutrition Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke German Institute of Human Nutrition Jahresbericht 2007–2008 www.dife.de Jahresbericht Annual Report 2007–2008 Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke für Ernährungsforschung Mitglied der Leibniz-Gemeinschaft Member of the Leibniz Association Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke German Institute of Human Nutrition Jahresbericht Annual Report 2007–2008 Mitglied der Leibniz-Gemeinschaft Member of the Leibniz Association Impressum/Imprint: Herausgeber/Publisher: Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke Institut der Leibniz-Gemeinschaft (WGL) Arthur-Scheunert-Allee 114-116 14558 Nuthetal http://www.dife.de Redaktion/Editors: Prof. Dr. Dr. Hans-Georg Joost Dr. Gisela Olias Dr. Lynne Rogers Redaktionsassistenz/ Editorial assistant: Susann-Cathérine Ruprecht Stephanie Wirth Autoren/Authors: Autoren der Abteilungsbeiträge sind die jeweiligen Abteilungs- oder Arbeitsgruppenleiter/innen. Gesamtherstellung: Schröders Agentur für Design · Druck · Verlag Vopeliuspfad 6 14169 Berlin www.schroeders-agentur.de Bildnachweis/Photocredits: Cover: DIfE; 2. Bild von links oben Stefan Günther Innenteil: DIfE; S. 7 Axel Scheidig; S. 66 Ingeborg van Leeuwen-Bol; S. 67+68 Ralf Günther; S. 73 HU Berlin DIfE-Hauptgebäude / DIfE main entrance DIfE kurzgefasst DIfE in brief Das Deutsche Institut für Ernährungsfor - The mission of the German Institute of schung Potsdam-Rehbrücke (DIfE) hat die Human Nutrition (DIfE) is to carry out Aufgabe, experimentelle und angewand - experimental and clinical research in the te Forschung auf dem Gebiet Er näh rung field of nutrition and health. Its aim is und Gesundheit zu betreiben. Das Ziel ist, to understand the molecular basis of die molekularen Ursachen ernährungsbe- nutrition-dependent diseases, and to dingter Erkrankungen zu erforschen und develop new strategies for prevention, neue Stra tegien für Prä ven tion, Therapie treatment, and nutritional recommen- und Ernäh rungs empfeh lungen zu ent wi- dations. Scientists at DIfE pursue these ckeln. Die Grund lagen dafür werden von scientific goals by interdisciplinary co op- den am DIfE tätigen Wissen schaftlern in eration comprising a broad spectrum of interdisziplinärer Zusam men arbeit mit experimental and epidemiological einem breiten natur wissen schaft lichen, methods. A particular focus of the insti- medizinischen und epidemiologischen tute is research on the most important Methoden spek trum er arbeitet. Dabei diseases at present, i.e., obesity, dia- konzentriert sich das Institut be son ders betes, and cancer, whose development auf die zurzeit wichtigsten Er kran kun gen, may involve nutrition-dependent fac- an deren Ent stehung ernährungs be - tors. dingte Faktoren beteiligt sein können: DIfE was established in 1992 by the Adipositas, Dia betes und Krebs. Federal Republic of Germany and the Das DIfE wurde 1992 von der Bundes repu - State of Brandenburg as an independ- blik Deutschland und dem Land Branden - ent foundation. It is a member of the burg als selbst stän dige Stiftung des öf - Leibniz Association, an alliance of fent lichen Rechts gegründet und ist scientific institutions. DIfE originated Mit glied der Leibniz-Gemeinschaft. Her - from the Zentralinstitut für Ernährung vor gegangen ist das DIfE aus dem Zen - der Akademie der Wissenschaften of the tralinstitut für Ernäh rung der Aka demie German Democratic Republic, which was der Wissenschaften der DDR, das seinen derived from the Institut für Ernäh rung Ursprung in dem 1946 in Rehbrücke ge - und Verpflegungswissen schaft, where gründeten Institut für Ernäh rung und nutrition research had started in 1946. Verpflegungswissenschaft hat. The academic members of the DIfE have Mitarbeiter des DIfE übernehmen Lehr - teaching obligations in nutritional sci- verpflich tungen im Studiengang Ernäh - ence at the Universität Potsdam and in rungs wissenschaft an der Universität medicine at the Freie Universität Berlin. Potsdam und im Studiengang Medizin an der Freien Universität Berlin. Vorwort 4 Preface The German Institute of Human Nutri - Gemäß seinem Gründungsauftrag unter- tion (DIfE) investigates the associations sucht das Deutsche Institut für Ernäh rungs- between nutrition and diseases with a forschung Potsdam-Rehbrücke (DIfE) die unique combination of experimental, Zusammenhänge zwischen Ernährung clinical, and epidemiological research. und Krankheitsentstehung in einer für Its work has laid the groundwork for sci- Deutschland einzigartigen Kombination entifically based nutritional recom- von molekularer, klinischer und epidemio - mendations, and has put DIfE into the logischer Ernährungsforschung. Durch position of a national center of compe- seine Arbeiten schafft es nicht nur Grund - tence in nutritional research. lagen für wissenschaftlich basierte Er - In the past seven years, DIfE further nährungsempfehlungen, sondern es hat Prof. Dr. Dr. Dr. developed its research profile, prioritiz- sich in den 17 Jahren seines Bestehens Hans-Georg Joost Hartmut Schulz ing the programs (1) role of nutrition in auch als nationales Kompetenzzentrum cancer development and, (2) cause and auf dem Gebiet der Ernährungsforschung consequences of the metabolic syn- etabliert. DIfE seine Aktivitäten mit denen anderer drome. Both research programs are In den letzten sieben Jahren hat das DIfE Forschungsinstitute vernetzt. Auf euro- major challenges for modern nutri- sein aktuelles Forschungsprofil ausgebil- päischer Ebene hat es sich verschiedenen tional medicine. The metabolic syn- det. Es untersucht vorrangig die Rolle der von der Europäischen Union geförderten drome includes visceral obesity, ele- Ernährung in der Krebsentstehung sowie Kompetenz-Netzwerken angeschlossen. vated blood pressure, abnormal blood die Ursachen und Folgen des Meta boli - Auf nationaler Ebene ist es unter anderem lipids, and a high risk of type 2 diabetes schen Syndroms, das durch Übergewicht, Mitglied des nationalen Genomfor schungs- which is one of the most prevalent and Bluthochdruck, einen gestörten Fettstoff- netzes. Ebenso ist das DIfE an mehreren costly diseases. Its prevalence is cur- wechsel und ein hohes Diabetesrisiko vom Bundesministerium für Bildung und rently rising continuously, and thereby charakterisiert ist. Beide Forschungs - Forschung (BMBF) geförderten Verbund - requires a massive research effort to schwerpunkte können als wesentliche projekten beteiligt. Diese Projekte zielen counteract this trend. On July 1 2008, Herausforderungen der modernen Er- darauf ab, den Einfluss von Nahrungs - the Leibniz Association established a nährungsmedizin betrachtet werden. komponenten auf den Stoff wechsel zu research center for diabetes and meta- Besonders der Typ-2-Diabetes ist mit untersuchen oder Zusam men hänge zwi- bolic disease. Participating institutions rund sechs Millionen Fällen in Deutsch - schen Ernährungs verhal ten und Krank - are DIfE, the German Diabetes Center in land eine der häufigsten Erkrankungen heitsentstehung aufzu klären. Die For - Düsseldorf, and the University Hospital und zählt aus volkswirtschaftlicher Sicht schungsergebnisse dieser Studien sollen of Tübingen. The intense cooperation of zu den teuersten chronischen Leiden. Da Wirtschaft und Wissenschaft gleicher- these research centers will expedite die Zahl der Diabetiker stetig steigt, ist die maßen zugänglich gemacht werden. progress in risk assessment, prevention, Wissenschaft mehr denn je gefordert, Zur besonderen Förderung des wissen- and treatment of diabetes. neue Wege zu finden, diesem Trend ent- schaftlichen Nachwuchs hat das DIfE ein Nutritional research questions cannot gegenzuwirken. Aus diesem Grund hat die internationales Leibniz-Graduierten kol - be answered by a single institution, so Leibniz-Gemeinschaft am 1. Juli 2008 ein leg etabliert, an dem begabte Jung - DIfE has joined forces with other Forschungszentrum für Diabetes und wissenschaftler ein Promotionsstudium research facilities and with European Stoffwechselerkrankungen gegründet, absolvieren. Mit seinem Thema „Senso - networks of competence. At a national an dem das DIfE, das Deutsche Diabetes- rische, endokrine und metabolische Kon - level, DIfE is involved in the National Zentrum in Düsseldorf und das Uni ver - trolle der Nahrungsauswahl“ bearbeitet Genome Research Network and con- sitätsklinikum Tübingen beteiligt sind. das Kolleg eine aktuelle Fragestellung der ducts several coordinated projects that Die intensive Kooperation der drei Ein - Ernährungsforschung. are sponsored by the Federal Ministry of richtungen wird dazu beitragen, schneller Der Vorstand möchte allen Mitarbeite - Education and Research (BMBF). Fortschritte in der Vorhersage, Vor beu - rinnen und Mitarbeitern des DIfE herzlich For the advancement of junior scien- gung und Therapie der Erkrankung zu für ihre Arbeit danken. Ebenso gilt unser tists, DIfE established an international erzielen. herzlicher Dank allen Freunden und postgraduate program where out- Da auch andere Fragestellungen auf Förderern aus Wissenschaft, Politik und standing young researchers complete dem Gebiet der Ernährungsforschung Wirtschaft. Mit Ihrer Unterstützung wer- their doctorate. The topic of this pro- nicht mehr von einem einzelnen Institut den wir das Institut auch in Zukunft gram is “Sensory, endocrine, and meta- allein bearbeitet werden können, hat das erfolgreich weiterentwickeln! bolic control of food selection”. The Board of Directors wishes to thank all staff members of the Institute for their excellent
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