Anti-TAB1 (aa 1-288) polyclonal antibody (DPABH- 03372) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Antigen Description May be an important signaling intermediate between TGFB receptors and MAP3K7/TAK1. May play an important role in mammalian embryogenesis.

Immunogen Recombinant fragment corresponding to a region within amino acids 1-288 of Human TAB1.

Isotype IgG

Source/Host Rabbit

Species Reactivity Human

Purification Immunogen affinity purified

Conjugate Unconjugated

Applications WB, ICC/IF

Format Liquid

Size 100 μl

Buffer pH: 7.00; Constituents: 0.75% Glycine, 1.21% Tris, 10% Glycerol

Preservative None

Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

GENE INFORMATION

Gene Name TAB1 TGF-beta activated 1/MAP3K7 binding protein 1 [ Homo sapiens ]

Official Symbol TAB1

Synonyms TAB1; TGF-beta activated kinase 1/MAP3K7 binding protein 1; MAP3K7IP1, activated protein kinase kinase kinase 7 interacting protein 1; TGF-beta-activated kinase 1 and MAP3K7- binding protein 1; mitogen activated protein kinase kinase kinase 7 interacting protein 1; TAK1 binding protein 1; TAK1-binding protein 1; transforming growth factor beta-activated kinase- binding protein 1; mitogen-activated protein kinase kinase kinase 7-interacting protein 1; 3-Tab1;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved MAP3K7IP1; MGC57664;

Entrez Gene ID 10454

Protein Refseq NP_006107

UniProt ID A8K6K3

Chromosome Location 22q13.1

Pathway Activated TLR4 signalling; Cytokine Signaling in Immune system; Herpes simplex infection; IL1- mediated signaling events; IRAK2 mediated activation of TAK1 complex; IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation;

Function catalytic activity; activator activity; kinase activator activity; protein binding;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved