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COVID-19 Publications - Week 05 2021 1328 Publications
Update February 1 - February 7, 2021, Dr. Peter J. Lansberg MD, PhD Weekly COVID-19 Literature Update will keep you up-to-date with all recent PubMed publications categorized by relevant topics COVID-19 publications - Week 05 2021 1328 Publications PubMed based Covid-19 weekly literature update For those interested in receiving weekly updates click here For questions and requests for topics to add send an e-mail [email protected] Reliable on-line resources for Covid 19 WHO Cochrane Daily dashbord BMJ Country Guidance The Lancet Travel restriction New England Journal of Medicine Covid Counter JAMA Covid forcasts Cell CDC Science AHA Oxford Universtiy Press ESC Cambridge Univeristy Press EMEA Springer Nature Evidence EPPI Elsevier Wikipedia Wiley Cardionerds - COVID-19 PLOS Genomic epidemiology LitCovid NIH-NLM Oxygenation Ventilation toolkit SSRN (Pre-prints) German (ICU) bed capacity COVID reference (Steinhauser Verlag) COVID-19 Projections tracker Retracted papers AAN - Neurology resources COVID-19 risk tools - Apps COVID-19 resources (Harvard) Web app for SARS-CoV2 mutations COVID-19 resources (McMasters) COVID-19 resources (NHLBI) COVID-19 resources (MEDSCAPE) COVID-19 Diabetes (JDRF) COVID-19 TELEMEDICINE (BMJ) Global Causes of death (Johns Hopkins) COVID-19 calculators (Medscap) Guidelines NICE Guidelines Covid-19 Korean CDC Covid-19 guidelines Flattening the curve - Korea IDSA COVID-19 Guidelines Airway Management Clinical Practice Guidelines (SIAARTI/EAMS, 2020) ESICM Ventilation Guidelines Performing Procedures on Patients With -
People, Plagues, and Prices in the Roman World: the Evidence from Egypt
People, Plagues, and Prices in the Roman World: The Evidence from Egypt KYLE HARPER The papyri of Roman Egypt provide some of the most important quantifiable data from a first-millennium economy. This paper builds a new dataset of wheat prices, land prices, rents, and wages over the entire period of Roman control in Egypt. Movements in both nominal and real prices over these centuries suggest periods of intensive and extensive economic growth as well as contraction. Across a timeframe that covers several severe mortality shocks, demographic changes appear to be an important, but by no means the only, force behind changes in factor prices. his article creates and analyzes a time series of wheat and factor Tprices for Egypt from AD 1 to the Muslim conquest, ~AD 641. From the time the territory was annexed by Octavian in 30 BCE until it was permanently taken around AD 641, Egypt was an important part of the Roman Empire. Famously, it supplied grain for the populations of Rome and later Constantinople, but more broadly it was integrated into the culture, society, and economy of the Roman Mediterranean. While every province of the sprawling Roman Empire was distinctive, recent work stresses that Egypt was not peculiar (Bagnall 1993; Rathbone 2007). Neither its Pharaonic legacy, nor the geography of the Nile valley, make it unrepresentative of the Roman world. In one crucial sense, however, Roman Egypt is truly unique: the rich- ness of its surviving documentation. Because of the valley’s arid climate, tens of thousands of papyri, covering the entire spectrum of public and private documents, survive from the Roman period (Bagnall 2009). -
Bibliographic Review on the Historical Memory of Previous
REVISIONES Bibliographic review on the historical memory of previous pandemics in nursing reviews on COVID-19: a secularly documented reality Revisión bibliográfica sobre la memoria histórica de pandemias anteriores en revisiones de enfermería sobre COVID-19: una realidad secularmente documentada Joaquín León Molina1 M. Fuensanta Hellín Gil1 Eva Abad Corpa2 1 Nurse Hospital Clínico Universitario Virgen de la Arrixaca de Murcia; Advanced Nursing Care Group of the Murcian Institute of Biosanitary Research Arrixaca. Murcia. Spain. 2 Associate nurse, Hospital General Universitario Reina Sofía de Murcia; Contracted Professor PhD linked University of Murcia. Advanced Nursing Care Group of the Murcian Institute of Biosanitary Research Arrixaca. Murcia. Spain. https://doi.org/10.6018/eglobal.456511 Received: 17/11/2020 Accepted: 10/01/2021 ABSTRACT: Introduction: Reviews for COVID-19 should reflect historical antecedents from previous pandemics. Objective: We plan to map the content of recent reviews in the nursing area on COVID-19 to see if it refers to health crises due to epidemics and infectious diseases. Methodology: Descriptive narrative review. The Science Web, PubMed and Lilacs were consulted to identify the reviews; The content of the documents was consulted to detect the presence of descriptors and terms related to pandemics prior to the 21st century of humanity, taking into account the inclusion criteria and objectives of the study. Results: Relevant reviews were found only in 11 documents of the 192 identified. Conclusions: There may be reluctance to use documentation published more than a century ago; However, it would be advisable not to lose the historical memory of pandemic crises that humanity has suffered for millennia Key words: Pandemics; Epidemics; History; Ancient History. -
The Politics of the Coronavirus and Its Impact on International Relations
Vol. 14(3), pp. 116-125, July-September 2020 DOI: 10.5897/AJPSIR2020.1271 Article Number: FA1630564661 ISSN: 1996-0832 Copyright ©2020 African Journal of Political Science and Author(s) retain the copyright of this article http://www.academicjournals.org/AJPSIR International Relations Full Length Research Paper The politics of the coronavirus and its impact on international relations Bheki Richard Mngomezulu Department of Political Science, Faculty of Economic and Management Sciences, University of the Western Cape, South Africa. Received 7 June, 2020; Accepted 1 July, 2020 Pandemic outbreaks are not a new phenomenon globally. There is plethora of evidence to substantiate this view. However, each epidemic has its own defining features, magnitude, and discernible impact. Societies are affected differently. The coronavirus or COVID-19 is not an incongruity. Although it is still active, thus making detailed empirical data inconclusive, it has already impacted societies in many ways - leaving indelible marks. Regarding methodology, this paper is an analytic and exploratory desktop study which draws evidence from different countries to advance certain arguments. It is mainly grounded in political science (specifically international relations) and history academic disciplines. Firstly, the paper begins by looking at how the coronavirus has affected international relations – both positively and negatively. Secondly, using examples from different countries, it argues that the virus has exposed the political leadership by bringing to bear endemic socio-economic inequalities which result in citizens responding differently to government regulations meant to flatten the curve of infection. Thirdly, in the context of Africa, the paper makes a compelling argument that some of the socio-economic situations found within the continent are remnants of colonialism and apartheid. -
Early History of Infectious Disease
© Jones and Bartlett Publishers. NOT FOR SALE OR DISTRIBUTION CHAPTER ONE EARLY HISTORY OF INFECTIOUS 1 DISEASE Kenrad E. Nelson, Carolyn F. Williams Epidemics of infectious diseases have been documented throughout history. In ancient Greece and Egypt accounts describe epidemics of smallpox, leprosy, tuberculosis, meningococcal infections, and diphtheria.1 The morbidity and mortality of infectious diseases profoundly shaped politics, commerce, and culture. In epidemics, none were spared. Smallpox likely disfigured and killed Ramses V in 1157 BCE, although his mummy has a significant head wound as well.2 At times political upheavals exasperated the spread of disease. The Spartan wars caused massive dislocation of Greeks into Athens triggering the Athens epidemic of 430–427 BCE that killed up to one half of the population of ancient Athens.3 Thucydides’ vivid descriptions of this epidemic make clear its political and cultural impact, as well as the clinical details of the epidemic.4 Several modern epidemiologists have hypothesized on the causative agent. Langmuir et al.,5 favor a combined influenza and toxin-producing staphylococcus epidemic, while Morrens and Chu suggest Rift Valley Fever.6 A third researcher, Holladay believes the agent no longer exists.7 From the earliest times, man has sought to understand the natural forces and risk factors affecting the patterns of illness and death in society. These theories have evolved as our understanding of the natural world has advanced, sometimes slowly, sometimes, when there are profound break- throughs, with incredible speed. Remarkably, advances in knowledge and changes in theory have not always proceeded in synchrony. Although wrong theories or knowledge have hindered advances in understanding, there are also examples of great creativity when scientists have successfully pursued their theories beyond the knowledge of the time. -
Design and Characterization of Inulin Conjugate for Improved Intracellular and Targeted Delivery of Pyrazinoic Acid to Monocytes
pharmaceutics Article Design and Characterization of Inulin Conjugate for Improved Intracellular and Targeted Delivery of Pyrazinoic Acid to Monocytes Franklin Afinjuomo 1, Thomas G. Barclay 1, Ankit Parikh 1, Yunmei Song 1, Rosa Chung 1, Lixin Wang 1, Liang Liu 1, John D. Hayball 1, Nikolai Petrovsky 2,3 and Sanjay Garg 1,* 1 School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, SA 5001, Australia; olumide.afi[email protected] (F.A.); [email protected] (T.G.B.); [email protected] (A.P.); [email protected] (Y.S.); [email protected] (R.C.); [email protected] (L.W.); [email protected] (L.L.); [email protected] (J.D.H.) 2 Vaxine Pty. Ltd., Adelaide, SA 5042, Australia; nikolai.petrovsky@flinders.edu.au 3 Department of Endocrinology, Flinders University, Adelaide, SA 5042, Australia * Correspondence: [email protected]; Tel.: +61-8-8302-1567 Received: 26 April 2019; Accepted: 16 May 2019; Published: 22 May 2019 Abstract: The propensity of monocytes to migrate into sites of mycobacterium tuberculosis (TB) infection and then become infected themselves makes them potential targets for delivery of drugs intracellularly to the tubercle bacilli reservoir. Conventional TB drugs are less effective because of poor intracellular delivery to this bacterial sanctuary. This study highlights the potential of using semicrystalline delta inulin particles that are readily internalised by monocytes for a monocyte-based drug delivery system. Pyrazinoic acid was successfully attached covalently to the delta inulin particles via a labile linker. -
Advances in Nanomaterials in Biomedicine
nanomaterials Editorial Advances in Nanomaterials in Biomedicine Elena Ryabchikova Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of Russian Academy of Science, 8 Lavrentiev Ave., 630090 Novosibirsk, Russia; [email protected] Keywords: nanotechnology; nanomedicine; biocompatible nanomaterials; diagnostics; nanocarriers; targeted drug delivery; tissue engineering Biomedicine is actively developing a methodological network that brings together biological research and its medical applications. Biomedicine, in fact, is at the front flank of the creation of the latest technologies for various fields in medicine, and, obviously, nanotechnologies occupy an important place at this flank. Based on the well-known breadth of the concept of “Biomedicine”, the boundaries of the Special Issue “Advances in Nanomaterials in Biomedicine” were not limited, and authors could present their work from various fields of nanotechnology, as well as new methods and nanomaterials intended for medical applications. This approach made it possible to make public not only specific developments, but also served as a kind of mirror reflecting the most active interest of researchers in a particular field of application of nanotechnology in biomedicine. The Special Issue brought together more than 110 authors from different countries, who submitted 11 original research articles and 7 reviews, and conveyed their vision of the problems of nanomaterials in biomedicine to the readers. A detailed and well-illustrated review on the main problems of nanomedicine in onco-immunotherapy was presented by Acebes-Fernández and co-authors [1]. It should be noted that the review is not limited to onco-immunotherapy, and gives a complete understanding of nanomedicine in general, which is useful for those new to this field. -
Fighting Ebola: a Strategy for Action
FIGHTING EBOLA: A STRATEGY FOR ACTION Vera Songwe, Nonresident Senior Fellow, Africa Growth Initiative THE PRIORITY Despite these overwhelming numbers, prog- ress is being made in the fight against these African populations continue to suffer under diseases. For example, malaria mortality rates in the heavy burden of disease despite overall sus- children in Africa were reduced by an estimat- tained increases in income levels over the last ed 54 percent between 2002 and 2012. Since decade. Three major diseases are among those 2000, there has been a 49 percent reduction responsible for health crises: malaria, HIV/AIDS in the overall malaria mortality rates in Africa. and tuberculosis, and, in 2014, the Ebola virus For HIV, by the end of 2012, about 68 percent emerged as a fourth virus with pandemic po- of eligible persons were receiving antiretroviral tential. treatment, an increase of more than 90 percent since 2009 (UNAIDS 2013). In 2012, for example, 80 percent of the estimat- ed 207 million malaria cases worldwide were However, 2014 in West Africa will be remem- found in Africa, and 90 percent of the estimat- bered not for progress made in combatting in- ed 627,000 global malaria deaths occurred in fectious diseases but as the year the Ebola virus Africa. On average, malaria kills a child every crippled three countries on the continent and minute, of which 90 percent occur among Afri- inflicted economic damage to many others. can children. Malaria-related anemia is estimat- The 20th Ebola outbreak globally has captured ed to cause thousands of deaths a year—and the attention of the world like none of the oth- for countries with endemic malaria, it is estimat- ers that have preceded it and like no other dis- ed that there is a 1.3 percentage point loss in ease has in recent history. -
Ebola Viral Disease Outbreak-2014: Implications and Pitfalls
View metadata, citation and similar papers at core.ac.uk brought to you by CORE OPINION ARTICLE published: 01 Decemberprovided by 2014 Frontiers - Publisher Connector PUBLIC HEALTH doi: 10.3389/fpubh.2014.00263 Ebola viral disease outbreak-2014: implications and pitfalls Mahip Acharya* Independent Researcher, Kathmandu, Nepal *Correspondence: [email protected] Edited by: Philip Arthur Mackowiak, University of Maryland School of Medicine, USA Reviewed by: Mohammad Mohseni Sajadi, Institute of Human Virology at the University of Maryland School of Medicine, USA Keywords: Ebola virus outbreak, zoonosis, pharmaceutical industries, ethics in drug approval, global health West Africa – consisting of countries hemorrhagic fever outbreak in southern numerous strains of a single virus species such as Guinea, Liberia, Sierra Leone, and Sudan and northern Zaire (5). Ebola viral and their continued mutation – as is the Nigeria – is the westernmost region of the disease, a zoonotic disease, has since been case with the current Ebola infection (8)– African continent. Afflicted by widespread observed intermittently in different regions often stymies the research for anti-viral poverty and political instability,WestAfrica of Central Africa (6), but none of those drugs. This is similar to the case with is one of the poorest regions in the world – has wreaked damage as monumental as the antibiotics, where bacterial resistance is a Liberia, Sierra Leone, and Guinea are ongoing outbreak. chief concern (9). Bacterial and viral dis- respectively ranked 174, 177, and178 out The current Ebola viral disease outbreak eases benefit from the ever-evolving genetic of 187 countries on the United Nations is turning out to be an insidious threat makeup of their agents, which are capable Development Program Human Develop- to the public health of West Africa – and of rapidly rendering a treatment ineffec- ment Index (1). -
Introducing Bionanotechnology Into Undergraduate Biomedical Engineering
AC 2009-504: INTRODUCING BIONANOTECHNOLOGY INTO UNDERGRADUATE BIOMEDICAL ENGINEERING Aura Gimm, Duke University J. Aura Gimm is Assistant Professor of the Practice and Associated Director of Undergraduate Studies in the Department of Biomedical Engineering at Duke University. She teaches courses in biomaterials, thermodynamics/kinetics, engineering design, and a new course in bionanotechnology. Dr. Gimm received her S.B. in Chemical Engineering and Biology from MIT, and her Ph.D. in Bioengineering from UC-Berkeley. Page 14.802.1 Page © American Society for Engineering Education, 2009 Introducing Bionanotechnology in Undergraduate Biomedical Engineering Abstract As a part of the NSF-funded Nanotechnology Undergraduate Education Program, we have developed and implemented a new upper division elective course in Biomedical Engineering titled “Introduction to Bionanotechnology Engineering”. The pilot course included five hands- on “Nanolab” modules that guided students through specific aspects of nanomaterials and engineering design in addition to lecture topics such as scaling effects, quantum effects, electrical/optical properties at nanoscale, self-assembly, nanostructures, nanofabrication, biomotors, biological designing, biosensors, etc. Students also interacted with researchers currently working in the areas of nanomedicine, self-assembly, tribiology, and nanobiomaterials to learn first-hand the engineering and design challenges. The course culminated with research or design proposals and oral presentations that addressed specific engineering/design issues facing nanobiotechnology and/or nanomedicine. The assessment also included an exam (only first offering), laboratory write-ups, reading of research journal articles and analysis, and an essay on ethical/societal implications of nanotechnology, and summative questionnaire. The course exposed students to cross-disciplinary intersections that occur between biomedical engineering, materials science, chemistry, physics, and biology when working at the nanoscale. -
The Antonine Plague Revisited
Arctos 52 (2018) 41–72 THE ANTONINE PLAGUE REVISITED R. P. Duncan-Jones* 1. Introduction The Roman world was no stranger to lethal epidemic. Systematic records over long periods suggest a significant disease outbreak roughly every 10 to 20 years.1 But the Antonine plague stood out for its force and virulence.2 Neverthe- less, Gilliam’s minimising account in 1961 rapidly became a standard view.3 But his interpretation no longer seems to be generally accepted.4 The writer * I am much indebted to Professors C. P. Jones and V. Nutton, together with the anonymous refer- ees, for their valuable help, although they bear no responsibility for any statement. I must also thank Dr A. M. Burnett for his kind help. 1 Paine - Storey (2012, 183) from the annalistic tradition for the years 490–292 and 212–165 BCE (also Duncan-Jones 1996, 111). An average of one epidemic outbreak every 11.6 years has been estimated for the period 541–750 CE (Stathakopoulos 2007, 105). 2 R. P. Duncan-Jones “The Impact of the Antonine Plague” JRA 9:1996, 108–36, called IAP below. The evidence for the later Cyprianic plague (Harper 2015) is also plentiful, but depends partly on contemporary Christian sources which happen to be rare in the Antonine period 3 Gilliam 1961. 4 See for example Lo Cascio 2012a, 7–9 and passim; Liebeschuetz 2001, 397; Papi 2004, 61; Jong- man 2006, 243; Sallares 2007, 37; Rathbone 2007, 700; Giardina 2007, 757; Malanima 2013, 27–8; Temin 2013, 84–5; Mattern 2013, 198–9; Harris 2016, 63, n.330; Harper 2017, 98–115; (in contrast to Bruun 2007 and 2012; cf. -
Nanotechnology in Regenerative Medicine: the Materials Side
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by UPCommons. Portal del coneixement obert de la UPC Review Nanotechnology in regenerative medicine: the materials side Elisabeth Engel, Alexandra Michiardi, Melba Navarro, Damien Lacroix and Josep A. Planell Institute for Bioengineering of Catalonia (IBEC), Department of Materials Science, Technical University of Catalonia, CIBER BBN, Barcelona, Spain Regenerative medicine is an emerging multidisciplinary structures and materials with nanoscale features that can field that aims to restore, maintain or enhance tissues mimic the natural environment of cells, to promote certain and hence organ functions. Regeneration of tissues can functions, such as cell adhesion, cell mobility and cell be achieved by the combination of living cells, which will differentiation. provide biological functionality, and materials, which act Nanomaterials used in biomedical applications include as scaffolds to support cell proliferation. Mammalian nanoparticles for molecules delivery (drugs, growth fac- cells behave in vivo in response to the biological signals tors, DNA), nanofibres for tissue scaffolds, surface modifi- they receive from the surrounding environment, which is cations of implantable materials or nanodevices, such as structured by nanometre-scaled components. Therefore, biosensors. The combination of these elements within materials used in repairing the human body have to tissue engineering (TE) is an excellent example of the reproduce the correct signals that guide the cells great potential of nanotechnology applied to regenerative towards a desirable behaviour. Nanotechnology is not medicine. The ideal goal of regenerative medicine is the in only an excellent tool to produce material structures that vivo regeneration or, alternatively, the in vitro generation mimic the biological ones but also holds the promise of of a complex functional organ consisting of a scaffold made providing efficient delivery systems.