This is a repository copy of Advanced kinetic modelling strategies: Towards adoption in clinical PET imaging. White Rose Research Online URL for this paper: http://eprints.whiterose.ac.uk/93618/ Version: Accepted Version Article: Kotasidis, FA, Tsoumpas, C and Rahmim, A (2014) Advanced kinetic modelling strategies: Towards adoption in clinical PET imaging. Clinical and Translational Imaging, 2 (3). pp. 219-237. ISSN 2281-5872 https://doi.org/10.1007/s40336-014-0069-8 Reuse Unless indicated otherwise, fulltext items are protected by copyright with all rights reserved. The copyright exception in section 29 of the Copyright, Designs and Patents Act 1988 allows the making of a single copy solely for the purpose of non-commercial research or private study within the limits of fair dealing. The publisher or other rights-holder may allow further reproduction and re-use of this version - refer to the White Rose Research Online record for this item. Where records identify the publisher as the copyright holder, users can verify any specific terms of use on the publisher’s website. Takedown If you consider content in White Rose Research Online to be in breach of UK law, please notify us by emailing
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[email protected] https://eprints.whiterose.ac.uk/ Advanced kinetic modeling strategies: towards adoption in clinical PET imaging Fotis A. Kotasidis1,2†, Charalampos Tsoumpas3, Arman Rahmim4 1Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospital, Geneva, Switzerland 2 Wolfson Molecular Imaging Centre, MAHSC, University of Manchester, Manchester, UK 3 Division of Medical Physics, University of Leeds, Leeds, UK 4 Department of Radiology, Johns Hopkins University, Baltimore, MD 21287, USA Abstract Positron emission tomography (PET) is a highly quantitative imaging modality and can probe a number of functional and biologic processes depending on the radio-labeled tracer.